{
	"name":"cfa03400",
	"children":[
	{
		"name":"Eukaryotic type",
		"children":[
		{
			"name":"SSBR (single strand breaks repair)",
			"children":[
			{
				"name":"Direct repair",
				"children":[
				{
					"name":"442978 MGMT; methylated-DNA--protein-cysteine methyltransferase\tK00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]"
				},
				{
					"name":"477524 ALKBH2; DNA oxidative demethylase ALKBH2\tK10859 ALKBH2; DNA oxidative demethylase [EC:1.14.11.33]"
				},
				{
					"name":"475938 ALKBH3; alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 isoform X2\tK10860 ALKBH3; mRNA N1-methyladenine demethylase [EC:1.14.11.54]"
				},
				{
					"name":"475008 ASCC3; activating signal cointegrator 1 complex subunit 3 isoform X1\tK18663 ASCC3; activating signal cointegrator complex subunit 3 [EC:5.6.2.4]"
				}
				]
			},
			{
				"name":"BER (base exicision repair)",
				"children":[
				{
					"name":"DNA glycosylases",
					"children":[
					{
						"name":"486315 UNG; uracil-DNA glycosylase\tK03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]"
					},
					{
						"name":"487208 CCNO; cyclin-O\tK10861 UDG2; uracil-DNA glycosylase 2 [EC:3.2.2.-]"
					},
					{
						"name":"475448 TDG; G\/T mismatch-specific thymine DNA glycosylase isoform X1\tK20813 TDG; thymine-DNA glycosylase [EC:3.2.2.29]"
					},
					{
						"name":"611597 MPG; DNA-3-methyladenine glycosylase isoform X1\tK03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]"
					},
					{
						"name":"486497 SMUG1; single-strand selective monofunctional uracil DNA glycosylase isoform X1\tK10800 SMUG1; single-strand selective monofunctional uracil DNA glycosylase [EC:3.2.2.-]"
					},
					{
						"name":"100856592 MUTYH; adenine DNA glycosylase isoform X7\tK03575 mutY; A\/G-specific adenine glycosylase [EC:3.2.2.31]"
					},
					{
						"name":"100684130 MBD4; methyl-CpG-binding domain protein 4 isoform X3\tK10801 MBD4; methyl-CpG-binding domain protein 4 [EC:3.2.2.-]"
					},
					{
						"name":"484666 OGG1; N-glycosylase\/DNA lyase isoform X2\tK03660 OGG1; N-glycosylase\/DNA lyase [EC:3.2.2.- 4.2.99.18]"
					},
					{
						"name":"611615 NEIL1; endonuclease 8-like 1 isoform X1\tK10567 NEIL1; endonuclease VIII-like 1 [EC:3.2.2.- 4.2.99.18]"
					},
					{
						"name":"486078 NEIL2; endonuclease 8-like 2\tK10568 NEIL2; endonuclease VIII-like 2 [EC:3.2.2.- 4.2.99.18]"
					},
					{
						"name":"475639 NEIL3; endonuclease 8-like 3 isoform X7\tK10569 NEIL3; endonuclease VIII-like 3 [EC:3.2.2.- 4.2.99.18]"
					},
					{
						"name":"610981 NTHL1; endonuclease III-like protein 1 isoform X3\tK10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]"
					}
					]
				},
				{
					"name":"AP endonucleases",
					"children":[
					{
						"name":"482558 APEX1; DNA-(apurinic or apyrimidinic site) endonuclease\tK10771 APEX1; AP endonuclease 1 [EC:3.1.11.2]"
					},
					{
						"name":"100855516 APEX2; DNA-(apurinic or apyrimidinic site) endonuclease 2\tK10772 APEX2; AP endonuclease 2 [EC:3.1.11.2]"
					}
					]
				},
				{
					"name":"Long Patch-BER factors",
					"children":[
					{
						"name":"DNA polymerase delta complex",
						"children":[
						{
							"name":"610047 POLD1; DNA polymerase delta catalytic subunit isoform X1\tK02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]"
						},
						{
							"name":"482686 POLD2; DNA polymerase delta subunit 2 isoform X3\tK02328 POLD2; DNA polymerase delta subunit 2"
						},
						{
							"name":"476806 POLD3; DNA polymerase delta subunit 3 isoform X3\tK03504 POLD3; DNA polymerase delta subunit 3"
						},
						{
							"name":"611847 DNA polymerase delta subunit 4 isoform X4\tK03505 POLD4; DNA polymerase delta subunit 4"
						}
						]
					},
					{
						"name":"DNA polymerase epsilon complex",
						"children":[
						{
							"name":"486223 POLE; DNA polymerase epsilon catalytic subunit A isoform X2\tK02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]"
						},
						{
							"name":"608973 POLE2; DNA polymerase epsilon subunit 2 isoform X8\tK02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]"
						},
						{
							"name":"612550 POLE3; DNA polymerase epsilon subunit 3\tK02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]"
						},
						{
							"name":"483096 POLE4; DNA polymerase epsilon subunit 4 isoform X3\tK03506 POLE4; DNA polymerase epsilon subunit 4 [EC:2.7.7.7]"
						}
						]
					},
					{
						"name":"477166 PCNA; proliferating cell nuclear antigen\tK04802 PCNA; proliferating cell nuclear antigen"
					},
					{
						"name":"476063 FEN1; flap endonuclease 1\tK04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]"
					},
					{
						"name":"100686967 LIG1; DNA ligase 1 isoform X1\tK10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]"
					}
					]
				},
				{
					"name":"Short Patch-BER factors",
					"children":[
					{
						"name":"494001 POLB; DNA polymerase beta isoform X2\tK02330 POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-]"
					},
					{
						"name":"476447 XRCC1; DNA repair protein XRCC1\tK10803 XRCC1; DNA-repair protein XRCC1"
					},
					{
						"name":"491145 LIG3; DNA ligase 3 isoform X1\tK10776 LIG3; DNA ligase 3 [EC:6.5.1.1]"
					}
					]
				},
				{
					"name":"Other BER factors",
					"children":[
					{
						"name":"490828 TDP1; tyrosyl-DNA phosphodiesterase 1 isoform X1\tK10862 TDP1; tyrosyl-DNA phosphodiesterase 1 [EC:3.1.4.-]"
					},
					{
						"name":"442943 APTX; aprataxin\tK10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]"
					},
					{
						"name":"481405 APLF; aprataxin and PNK-like factor isoform X3\tK13295 APLF; aprataxin and PNK-like factor [EC:3.1.-.-]"
					},
					{
						"name":"484373 PNKP; bifunctional polynucleotide phosphatase\/kinase isoform X1\tK08073 PNKP; bifunctional polynucleotide phosphatase\/kinase [EC:3.1.3.32 2.7.1.78]"
					},
					{
						"name":"100682891 LOW QUALITY PROTEIN: high mobility group protein B1-like\tK10802 HMGB1; high mobility group protein B1"
					},
					{
						"name":"403170 HMGB1; high mobility group protein B1\tK10802 HMGB1; high mobility group protein B1"
					},
					{
						"name":"608341 POLL; DNA polymerase lambda isoform X2\tK03512 POLL; DNA polymerase lambda [EC:2.7.7.7 4.2.99.-]"
					},
					{
						"name":"490385 PARP1; poly [ADP-ribose] polymerase 1\tK24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30]"
					},
					{
						"name":"475392 PARP2; poly [ADP-ribose] polymerase 2\tK28005 PARP2; poly [ADP-ribose] polymerase 2 [EC:2.4.2.30]"
					},
					{
						"name":"477348 PARP4; protein mono-ADP-ribosyltransferase PARP4\tK10798 PARP3_4; protein mono-ADP-ribosyltransferase 3\/4 [EC:2.4.2.-]"
					},
					{
						"name":"484745 PARP3; protein mono-ADP-ribosyltransferase PARP3\tK10798 PARP3_4; protein mono-ADP-ribosyltransferase 3\/4 [EC:2.4.2.-]"
					}
					]
				}
				]
			},
			{
				"name":"NER (nucleotide excision repair)",
				"children":[
				{
					"name":"GGR (global genome repair) factors",
					"children":[
					{
						"name":"XPC-HR23B-CETN2 complex",
						"children":[
						{
							"name":"476521 XPC; DNA repair protein complementing XP-C cells isoform X1\tK10838 XPC; xeroderma pigmentosum group C-complementing protein"
						},
						{
							"name":"481656 RAD23B; UV excision repair protein RAD23 homolog B isoform X2\tK10839 RAD23; UV excision repair protein RAD23"
						},
						{
							"name":"484922 RAD23A; UV excision repair protein RAD23 homolog A isoform X1\tK10839 RAD23; UV excision repair protein RAD23"
						},
						{
							"name":"481078 CETN2; centrin-2\tK10840 CETN2; centrin-2"
						},
						{
							"name":"482008 LOW QUALITY PROTEIN: centrin-2-like isoform X1\tK10840 CETN2; centrin-2"
						}
						]
					},
					{
						"name":"Cul4-DDB2 complex",
						"children":[
						{
							"name":"474494 RBX1; E3 ubiquitin-protein ligase RBX1 isoform X2\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
						},
						{
							"name":"492102 CUL4B; cullin-4B isoform X3\tK10609 CUL4; cullin 4"
						},
						{
							"name":"607683 CUL4A; cullin-4A isoform X5\tK10609 CUL4; cullin 4"
						},
						{
							"name":"476067 DDB1; DNA damage-binding protein 1\tK10610 DDB1; DNA damage-binding protein 1"
						},
						{
							"name":"483626 DDB2; DNA damage-binding protein 2 isoform X1\tK10140 DDB2; DNA damage-binding protein 2"
						}
						]
					},
					{
						"name":"NER4 complex"
					}
					]
				},
				{
					"name":"TCR (transcription coupled repair) factors",
					"children":[
					{
						"name":"DNA-directed RNA polymerase II complex",
						"children":[
						{
							"name":"479483 POLR2A; DNA-directed RNA polymerase II subunit RPB1\tK03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]"
						},
						{
							"name":"475152 POLR2B; DNA-directed RNA polymerase II subunit RPB2\tK03010 RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]"
						},
						{
							"name":"478109 POLR2C; DNA-directed RNA polymerase II subunit RPB3\tK03011 RPB3; DNA-directed RNA polymerase II subunit RPB3"
						},
						{
							"name":"483863 POLR2D; DNA-directed RNA polymerase II subunit RPB4\tK03012 RPB4; DNA-directed RNA polymerase II subunit RPB4"
						},
						{
							"name":"611859 POLR2E; DNA-directed RNA polymerases I, II, and III subunit RPABC1 isoform X1\tK03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1"
						},
						{
							"name":"474512 POLR2F; DNA-directed RNA polymerases I, II, and III subunit RPABC2 isoform X1\tK03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2"
						},
						{
							"name":"476052 POLR2G; DNA-directed RNA polymerase II subunit RPB7 isoform X2\tK03015 RPB7; DNA-directed RNA polymerase II subunit RPB7"
						},
						{
							"name":"478656 POLR2H; DNA-directed RNA polymerases I, II, and III subunit RPABC3\tK03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3"
						},
						{
							"name":"476476 POLR2I; DNA-directed RNA polymerase II subunit RPB9\tK03017 RPB9; DNA-directed RNA polymerase II subunit RPB9"
						},
						{
							"name":"111090847 POLR2L; DNA-directed RNA polymerases I, II, and III subunit RPABC5\tK03007 RPABC5; DNA-directed RNA polymerases I, II, and III subunit RPABC5"
						},
						{
							"name":"100686835 POLR2J; DNA-directed RNA polymerase II subunit RPB11-a isoform X1\tK03008 RPB11; DNA-directed RNA polymerase II subunit RPB11"
						},
						{
							"name":"100688583 POLR2K; DNA-directed RNA polymerases I, II, and III subunit RPABC4\tK03009 RPABC4; DNA-directed RNA polymerases I, II, and III subunit RPABC4"
						},
						{
							"name":"119870926 DNA-directed RNA polymerases I, II, and III subunit RPABC4-like\tK03009 RPABC4; DNA-directed RNA polymerases I, II, and III subunit RPABC4"
						}
						]
					},
					{
						"name":"Cul4-CSA complex",
						"children":[
						{
							"name":"474494 RBX1; E3 ubiquitin-protein ligase RBX1 isoform X2\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
						},
						{
							"name":"492102 CUL4B; cullin-4B isoform X3\tK10609 CUL4; cullin 4"
						},
						{
							"name":"607683 CUL4A; cullin-4A isoform X5\tK10609 CUL4; cullin 4"
						},
						{
							"name":"476067 DDB1; DNA damage-binding protein 1\tK10610 DDB1; DNA damage-binding protein 1"
						},
						{
							"name":"487225 ERCC8; DNA excision repair protein ERCC-8 isoform X3\tK10570 ERCC8; DNA excision repair protein ERCC-8"
						}
						]
					},
					{
						"name":"Other TCR factor",
						"children":[
						{
							"name":"477747 ERCC6; DNA excision repair protein ERCC-6\tK10841 ERCC6; DNA excision repair protein ERCC-6"
						},
						{
							"name":"488812 UVSSA; UV-stimulated scaffold protein A isoform X1\tK23720 UVSSA; UV-stimulated scaffold protein A"
						},
						{
							"name":"100687887 ELOF1; transcription elongation factor 1 homolog isoform X1\tK25829 ELOF1; transcription elongation factor 1"
						}
						]
					}
					]
				},
				{
					"name":"TFIIH complex",
					"children":[
					{
						"name":"476105 ERCC3; general transcription and DNA repair factor IIH helicase subunit XPB\tK10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]"
					},
					{
						"name":"493995 ERCC2; general transcription and DNA repair factor IIH helicase subunit XPD isoform X1\tK10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]"
					},
					{
						"name":"476881 GTF2H1; general transcription factor IIH subunit 1\tK03141 TFIIH1; transcription initiation factor TFIIH subunit 1"
					},
					{
						"name":"478089 general transcription factor IIH subunit 2\tK03142 TFIIH2; transcription initiation factor TFIIH subunit 2"
					},
					{
						"name":"100685309 LOW QUALITY PROTEIN: general transcription factor IIH subunit 3-like\tK03143 TFIIH3; transcription initiation factor TFIIH subunit 3"
					},
					{
						"name":"477446 GTF2H3; general transcription factor IIH subunit 3 isoform X2\tK03143 TFIIH3; transcription initiation factor TFIIH subunit 3"
					},
					{
						"name":"612182 GTF2H5; general transcription factor IIH subunit 5\tK10845 TTDA; TFIIH basal transcription factor complex TTD-A subunit"
					},
					{
						"name":"608441 CDK7; cyclin-dependent kinase 7 isoform X1\tK02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]"
					},
					{
						"name":"479156 CCNH; cyclin-H isoform X1\tK06634 CCNH; cyclin H"
					},
					{
						"name":"480346 MNAT1; CDK-activating kinase assembly factor MAT1 isoform X3\tK10842 MNAT1; CDK-activating kinase assembly factor MAT1"
					}
					]
				},
				{
					"name":"RPA (replication factor A)",
					"children":[
					{
						"name":"100855690 RPA1; replication protein A 70 kDa DNA-binding subunit\tK07466 RFA1; replication factor A1"
					},
					{
						"name":"100856421 RPA2; replication protein A 32 kDa subunit\tK10739 RFA2; replication factor A2"
					},
					{
						"name":"481449 RPA3; replication protein A 14 kDa subunit\tK10740 RPA3; replication factor A3"
					}
					]
				},
				{
					"name":"Other NER factors",
					"children":[
					{
						"name":"481623 XPA; DNA repair protein complementing XP-A cells\tK10847 XPA; DNA-repair protein complementing XP-A cells"
					},
					{
						"name":"612282 ERCC1; DNA excision repair protein ERCC-1 isoform X1\tK10849 ERCC1; DNA excision repair protein ERCC-1"
					},
					{
						"name":"479842 ERCC4; DNA repair endonuclease XPF isoform X1\tK10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]"
					},
					{
						"name":"100855935 ERCC5; DNA repair protein complementing XP-G cells isoform X1\tK10846 ERCC5; DNA excision repair protein ERCC-5"
					},
					{
						"name":"100686967 LIG1; DNA ligase 1 isoform X1\tK10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]"
					},
					{
						"name":"477788 MMS19; MMS19 nucleotide excision repair protein homolog isoform X1\tK15075 MET18; DNA repair\/transcription protein MET18\/MMS19"
					},
					{
						"name":"611823 CCDC117; coiled-coil domain-containing protein 117 isoform X2\tK27967 CCDC117; coiled-coil domain-containing protein 117"
					},
					{
						"name":"475743 CIAO1; probable cytosolic iron-sulfur protein assembly protein CIAO1\tK24730 CIAO1; cytosolic iron-sulfur protein assembly protein CIAO1"
					},
					{
						"name":"478335 CIAO2A; cytosolic iron-sulfur assembly component 2A\tK26403 CIAO2; cytosolic iron-sulfur assembly component 2"
					},
					{
						"name":"611301 CIAO2B; cytosolic iron-sulfur assembly component 2B\tK26403 CIAO2; cytosolic iron-sulfur assembly component 2"
					},
					{
						"name":"477392 CUL3; cullin-3 isoform X5\tK03869 CUL3; cullin 3"
					},
					{
						"name":"489422 CUL5; LOW QUALITY PROTEIN: cullin-5\tK10612 CUL5; cullin 5"
					},
					{
						"name":"119866339 elongin-C-like\tK03872 ELOC; elongin-C"
					},
					{
						"name":"119870849 elongin-C-like\tK03872 ELOC; elongin-C"
					},
					{
						"name":"477914 ELOC; elongin-C\tK03872 ELOC; elongin-C"
					},
					{
						"name":"479873 ELOB; elongin-B isoform X1\tK03873 ELOB; elongin-B"
					},
					{
						"name":"478188 ELOA; elongin-A\tK15076 ELOA; elongin-A"
					},
					{
						"name":"480135 UBAP2L; ubiquitin-associated protein 2-like isoform X62\tK26545 UBAP2; ubiquitin-associated protein 2"
					},
					{
						"name":"481583 UBAP2; ubiquitin-associated protein 2 isoform X2\tK26545 UBAP2; ubiquitin-associated protein 2"
					}
					]
				}
				]
			},
			{
				"name":"MMR (mismatch excision repair)",
				"children":[
				{
					"name":"Mismatch and loop recognition factors",
					"children":[
					{
						"name":"494002 MSH2; DNA mismatch repair protein Msh2\tK08735 MSH2; DNA mismatch repair protein MSH2"
					},
					{
						"name":"479164 MSH3; DNA mismatch repair protein Msh3 isoform X1\tK08736 MSH3; DNA mismatch repair protein MSH3"
					},
					{
						"name":"474585 MSH6; DNA mismatch repair protein Msh6\tK08737 MSH6; DNA mismatch repair protein MSH6"
					}
					]
				},
				{
					"name":"MutL homologs",
					"children":[
					{
						"name":"478840 PMS1; PMS1 protein homolog 1 isoform X1\tK10864 PMS1; DNA mismatch repair protein PMS1"
					},
					{
						"name":"477019 MLH1; DNA mismatch repair protein Mlh1 isoform X2\tK08734 MLH1; DNA mismatch repair protein MLH1"
					},
					{
						"name":"479751 PMS2; mismatch repair endonuclease PMS2 isoform X1\tK10858 PMS2; DNA mismatch repair protein PMS2"
					},
					{
						"name":"480389 MLH3; DNA mismatch repair protein Mlh3 isoform X3\tK08739 MLH3; DNA mismatch repair protein MLH3"
					}
					]
				},
				{
					"name":"DNA polymerase delta complex",
					"children":[
					{
						"name":"610047 POLD1; DNA polymerase delta catalytic subunit isoform X1\tK02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]"
					},
					{
						"name":"482686 POLD2; DNA polymerase delta subunit 2 isoform X3\tK02328 POLD2; DNA polymerase delta subunit 2"
					},
					{
						"name":"476806 POLD3; DNA polymerase delta subunit 3 isoform X3\tK03504 POLD3; DNA polymerase delta subunit 3"
					},
					{
						"name":"611847 DNA polymerase delta subunit 4 isoform X4\tK03505 POLD4; DNA polymerase delta subunit 4"
					}
					]
				},
				{
					"name":"RPA (replication factor A)",
					"children":[
					{
						"name":"100855690 RPA1; replication protein A 70 kDa DNA-binding subunit\tK07466 RFA1; replication factor A1"
					},
					{
						"name":"100856421 RPA2; replication protein A 32 kDa subunit\tK10739 RFA2; replication factor A2"
					},
					{
						"name":"481449 RPA3; replication protein A 14 kDa subunit\tK10740 RPA3; replication factor A3"
					}
					]
				},
				{
					"name":"RFC (replication factor C)",
					"children":[
					{
						"name":"479112 RFC1; replication factor C subunit 1 isoform X3\tK10754 RFC1; replication factor C subunit 1"
					},
					{
						"name":"478667 RFC4; replication factor C subunit 4 isoform X1\tK10755 RFC2_4; replication factor C subunit 2\/4"
					},
					{
						"name":"489798 RFC2; replication factor C subunit 2 isoform X1\tK10755 RFC2_4; replication factor C subunit 2\/4"
					},
					{
						"name":"477308 RFC3; replication factor C subunit 3 isoform X2\tK10756 RFC3_5; replication factor C subunit 3\/5"
					},
					{
						"name":"477499 RFC5; replication factor C subunit 5 isoform X2\tK10756 RFC3_5; replication factor C subunit 3\/5"
					}
					]
				},
				{
					"name":"Other MMR factors",
					"children":[
					{
						"name":"477166 PCNA; proliferating cell nuclear antigen\tK04802 PCNA; proliferating cell nuclear antigen"
					},
					{
						"name":"100855525 EXO1; exonuclease 1 isoform X1\tK10746 EXO1; exonuclease 1 [EC:3.1.-.-]"
					},
					{
						"name":"100682891 LOW QUALITY PROTEIN: high mobility group protein B1-like\tK10802 HMGB1; high mobility group protein B1"
					},
					{
						"name":"403170 HMGB1; high mobility group protein B1\tK10802 HMGB1; high mobility group protein B1"
					},
					{
						"name":"100686967 LIG1; DNA ligase 1 isoform X1\tK10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]"
					},
					{
						"name":"487529 WDR76; WD repeat-containing protein 76 isoform X3\tK24755 WDR76; WD repeat-containing protein 76"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"DSBR (double strand breaks repair)",
			"children":[
			{
				"name":"HR (homologous recombination)",
				"children":[
				{
					"name":"MRN(MRX) complex",
					"children":[
					{
						"name":"494006 MRE11; double-strand break repair protein MRE11 isoform X1\tK10865 MRE11; double-strand break repair protein MRE11"
					},
					{
						"name":"474674 RAD50; DNA repair protein RAD50 isoform X2\tK10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]"
					},
					{
						"name":"611315 NBN; nibrin isoform X2\tK10867 NBN; nibrin"
					}
					]
				},
				{
					"name":"BRCA1-core complex",
					"children":[
					{
						"name":"403437 BRCA1; breast cancer type 1 susceptibility protein homolog\tK10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]"
					},
					{
						"name":"102156002 LOW QUALITY PROTEIN: BRCA1-associated RING domain protein 1-like isoform X3\tK10683 BARD1; BRCA1-associated RING domain protein 1"
					},
					{
						"name":"610190 BARD1; BRCA1-associated RING domain protein 1 isoform X1\tK10683 BARD1; BRCA1-associated RING domain protein 1"
					}
					]
				},
				{
					"name":"BRCA1-A complex",
					"children":[
					{
						"name":"403437 BRCA1; breast cancer type 1 susceptibility protein homolog\tK10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]"
					},
					{
						"name":"478459 ABRAXAS1; BRCA1-A complex subunit Abraxas 1 isoform X1\tK20774 FAM175A; BRCA1-A complex subunit Abraxas"
					},
					{
						"name":"611298 UIMC1; BRCA1-A complex subunit RAP80 isoform X2\tK20775 UIMC1; BRCA1-A complex subunit RAP80"
					},
					{
						"name":"476676 BABAM1; BRISC and BRCA1-A complex member 1\tK20776 BABAM; BRISC and BRCA1-A complex member 1"
					},
					{
						"name":"475711 BABAM2; BRISC and BRCA1-A complex member 2 isoform X2\tK12173 BRE; BRCA1-A complex subunit BRE"
					},
					{
						"name":"610150 LOW QUALITY PROTEIN: lys-63-specific deubiquitinase BRCC36-like\tK11864 BRCC3; BRCA1\/BRCA2-containing complex subunit 3 [EC:3.4.19.-]"
					},
					{
						"name":"612642 BRCC3; lys-63-specific deubiquitinase BRCC36 isoform X4\tK11864 BRCC3; BRCA1\/BRCA2-containing complex subunit 3 [EC:3.4.19.-]"
					}
					]
				},
				{
					"name":"BRCA1-B complex",
					"children":[
					{
						"name":"403437 BRCA1; breast cancer type 1 susceptibility protein homolog\tK10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]"
					},
					{
						"name":"491122 BRIP1; Fanconi anemia group J protein\tK15362 BRIP1; fanconi anemia group J protein [EC:5.6.2.3]"
					},
					{
						"name":"477070 TOPBP1; DNA topoisomerase 2-binding protein 1 isoform X2\tK10728 TOPBP1; topoisomerase (DNA) II binding protein 1"
					}
					]
				},
				{
					"name":"BRCA1-C complex",
					"children":[
					{
						"name":"403437 BRCA1; breast cancer type 1 susceptibility protein homolog\tK10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]"
					},
					{
						"name":"111094686 DNA endonuclease RBBP8-like\tK20773 RBBP8; DNA endonuclease RBBP8 [EC:3.1.-.-]"
					},
					{
						"name":"480175 RBBP8; DNA endonuclease RBBP8\tK20773 RBBP8; DNA endonuclease RBBP8 [EC:3.1.-.-]"
					},
					{
						"name":"494006 MRE11; double-strand break repair protein MRE11 isoform X1\tK10865 MRE11; double-strand break repair protein MRE11"
					},
					{
						"name":"474674 RAD50; DNA repair protein RAD50 isoform X2\tK10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]"
					},
					{
						"name":"611315 NBN; nibrin isoform X2\tK10867 NBN; nibrin"
					}
					]
				},
				{
					"name":"BRCA complex",
					"children":[
					{
						"name":"403437 BRCA1; breast cancer type 1 susceptibility protein homolog\tK10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]"
					},
					{
						"name":"474180 BRCA2; breast cancer type 2 susceptibility protein\tK08775 BRCA2; breast cancer 2 susceptibility protein"
					},
					{
						"name":"608527 PALB2; partner and localizer of BRCA2\tK10897 PALB2; partner and localizer of BRCA2"
					},
					{
						"name":"403568 RAD51; DNA repair protein RAD51 homolog 1\tK04482 RAD51; DNA repair protein RAD51"
					}
					]
				},
				{
					"name":"RecA family proteins",
					"children":[
					{
						"name":"403568 RAD51; DNA repair protein RAD51 homolog 1\tK04482 RAD51; DNA repair protein RAD51"
					},
					{
						"name":"490746 RAD51B; DNA repair protein RAD51 homolog 2 isoform X2\tK10869 RAD51L1; RAD51-like protein 1"
					},
					{
						"name":"480573 RAD51C; DNA repair protein RAD51 homolog 3 isoform X1\tK10870 RAD51L2; RAD51-like protein 2"
					},
					{
						"name":"491143 RAD51D; DNA repair protein RAD51 homolog 4 isoform X2\tK10871 RAD51L3; RAD51-like protein 3"
					},
					{
						"name":"475548 XRCC2; DNA repair protein XRCC2\tK10879 XRCC2; DNA-repair protein XRCC2"
					},
					{
						"name":"100687200 XRCC3; DNA repair protein XRCC3\tK10880 XRCC3; DNA-repair protein XRCC3"
					}
					]
				},
				{
					"name":"Rad52 family proteins",
					"children":[
					{
						"name":"477729 RAD52; DNA repair protein RAD52 homolog isoform X1\tK10873 RAD52; DNA repair and recombination protein RAD52"
					},
					{
						"name":"100683711 LOW QUALITY PROTEIN: uncharacterized protein LOC100683711\tK10874 RDM1; RAD52 motif-containing protein 1"
					}
					]
				},
				{
					"name":"Rad54 family proteins",
					"children":[
					{
						"name":"475368 RAD54L; DNA repair and recombination protein RAD54-like isoform X3\tK10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]"
					},
					{
						"name":"476608 RAD54L2; helicase ARIP4 isoform X1\tK10876 RAD54L2; RAD54-like protein 2 [EC:5.6.2.-]"
					},
					{
						"name":"487053 RAD54B; DNA repair and recombination protein RAD54B isoform X3\tK10877 RAD54B; DNA repair and recombination protein RAD54B [EC:5.6.2.-]"
					}
					]
				},
				{
					"name":"RecQ family DNA helicases",
					"children":[
					{
						"name":"486641 RECQL; ATP-dependent DNA helicase Q1\tK10899 RECQL; ATP-dependent DNA helicase Q1 [EC:5.6.2.4]"
					},
					{
						"name":"493997 WRN; Werner syndrome ATP-dependent helicase isoform X5\tK10900 WRN; werner syndrome ATP-dependent helicase [EC:5.6.2.4]"
					},
					{
						"name":"100685609 BLM; Bloom syndrome protein isoform X2\tK10901 BLM; bloom syndrome protein [EC:5.6.2.4]"
					},
					{
						"name":"482101 RECQL4; ATP-dependent DNA helicase Q4 isoform X1\tK10730 RECQL4; ATP-dependent DNA helicase Q4 [EC:5.6.2.4]"
					},
					{
						"name":"483317 RECQL5; ATP-dependent DNA helicase Q5 isoform X1\tK10902 RECQL5; ATP-dependent DNA helicase Q5 [EC:5.6.2.4]"
					}
					]
				},
				{
					"name":"Bloom's syndrome complex (BTR)",
					"children":[
					{
						"name":"100685609 BLM; Bloom syndrome protein isoform X2\tK10901 BLM; bloom syndrome protein [EC:5.6.2.4]"
					},
					{
						"name":"477576 TOP3B; DNA topoisomerase 3-beta-1 isoform X1\tK03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]"
					},
					{
						"name":"489537 TOP3A; DNA topoisomerase 3-alpha\tK03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]"
					},
					{
						"name":"100684392 RMI1; recQ-mediated genome instability protein 1 isoform X1\tK10990 RMI1; RecQ-mediated genome instability protein 1"
					},
					{
						"name":"609907 RMI2; recQ-mediated genome instability protein 2\tK15365 RMI2; RecQ-mediated genome instability protein 2"
					}
					]
				},
				{
					"name":"RPA (replication factor A)",
					"children":[
					{
						"name":"100855690 RPA1; replication protein A 70 kDa DNA-binding subunit\tK07466 RFA1; replication factor A1"
					},
					{
						"name":"100856421 RPA2; replication protein A 32 kDa subunit\tK10739 RFA2; replication factor A2"
					},
					{
						"name":"481449 RPA3; replication protein A 14 kDa subunit\tK10740 RPA3; replication factor A3"
					}
					]
				},
				{
					"name":"Protein phosphatase 4",
					"children":[
					{
						"name":"489947 PPP4C; serine\/threonine-protein phosphatase 4 catalytic subunit isoform X2\tK15423 PPP4C; serine\/threonine-protein phosphatase 4 catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"477273 serine\/threonine-protein phosphatase 4 regulatory subunit 1-like isoform X3\tK15424 PPP4R1; serine\/threonine-protein phosphatase 4 regulatory subunit 1"
					},
					{
						"name":"480207 PPP4R1; serine\/threonine-protein phosphatase 4 regulatory subunit 1 isoform X3\tK15424 PPP4R1; serine\/threonine-protein phosphatase 4 regulatory subunit 1"
					},
					{
						"name":"476556 PPP4R2; serine\/threonine-protein phosphatase 4 regulatory subunit 2 isoform X1\tK15425 PPP4R2; serine\/threonine-protein phosphatase 4 regulatory subunit 2"
					},
					{
						"name":"474603 PPP4R3B; serine\/threonine-protein phosphatase 4 regulatory subunit 3B isoform X2\tK17491 SMEK; protein phosphatase 4 regulatory subunit 3"
					},
					{
						"name":"491791 serine\/threonine-protein phosphatase 4 regulatory subunit 3B-like\tK17491 SMEK; protein phosphatase 4 regulatory subunit 3"
					},
					{
						"name":"612974 PPP4R3A; serine\/threonine-protein phosphatase 4 regulatory subunit 3A isoform X1\tK17491 SMEK; protein phosphatase 4 regulatory subunit 3"
					},
					{
						"name":"490837 PPP4R4; serine\/threonine-protein phosphatase 4 regulatory subunit 4 isoform X5\tK15426 PPP4R4; serine\/threonine-protein phosphatase 4 regulatory subunit 4"
					}
					]
				},
				{
					"name":"AP-5 complex",
					"children":[
					{
						"name":"476023 AP5B1; AP-5 complex subunit beta-1\tK19022 AP5B1; AP-5 complex subunit beta-1"
					},
					{
						"name":"100685159 LOW QUALITY PROTEIN: AP-5 complex subunit mu-1 isoform X2\tK19023 AP5M1; AP-5 complex subunit mu-1"
					},
					{
						"name":"609098 AP5S1; AP-5 complex subunit sigma-1\tK19024 AP5S1; AP-5 complex subunit sigma-1"
					},
					{
						"name":"609375 AP5Z1; AP-5 complex subunit zeta-1 isoform X1\tK19025 AP5Z1; AP-5 complex subunit zeta-1"
					}
					]
				},
				{
					"name":"SMC5-SMC6 complex",
					"children":[
					{
						"name":"476327 SMC5; structural maintenance of chromosomes protein 5 isoform X2\tK22803 SMC5; structural maintenance of chromosomes protein 5"
					},
					{
						"name":"475675 SMC6; structural maintenance of chromosomes protein 6\tK22804 SMC6; structural maintenance of chromosomes protein 6"
					},
					{
						"name":"610235 LRATD1; protein LRATD1\tK22805 FAM84A; protein FAM84A"
					},
					{
						"name":"479800 NSMCE1; non-structural maintenance of chromosomes element 1 homolog\tK22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27]"
					},
					{
						"name":"475096 NSMCE2; E3 SUMO-protein ligase NSE2 isoform X1\tK22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]"
					},
					{
						"name":"102153224 LOW QUALITY PROTEIN: non-structural maintenance of chromosomes element 4 homolog A-like\tK22825 NSMCE4; non-structural maintenance of chromosomes element 4"
					},
					{
						"name":"100687031 EID3; EP300-interacting inhibitor of differentiation 3\tK22826 EID3; EP300-interacting inhibitor of differentiation 3"
					},
					{
						"name":"488907 SLF1; SMC5-SMC6 complex localization factor protein 1 isoform X2\tK26126 SLF1; SMC5-SMC6 complex localization factor protein 1"
					},
					{
						"name":"612816 SLF2; SMC5-SMC6 complex localization factor protein 2 isoform X2\tK26127 SLF2; SMC5-SMC6 complex localization factor protein 2"
					},
					{
						"name":"489106 SIMC1; SUMO-interacting motif-containing protein 1\tK28408 SIMC1; SUMO-interacting motif-containing protein 1"
					}
					]
				},
				{
					"name":"Other HR factors",
					"children":[
					{
						"name":"491079 EME1; crossover junction endonuclease EME1 isoform X1\tK10882 EME1; crossover junction endonuclease EME1 [EC:3.1.22.-]"
					},
					{
						"name":"490072 EME2; LOW QUALITY PROTEIN: probable crossover junction endonuclease EME2 isoform X4\tK10883 EME2; crossover junction endonuclease EME2"
					},
					{
						"name":"490750 EXD2; exonuclease 3'-5' domain-containing protein 2 isoform X2\tK20777 EXD2; exonuclease 3'-5' domain-containing protein 2 [EC:3.1.11.1]"
					},
					{
						"name":"476021 MUS81; crossover junction endonuclease MUS81 isoform X4\tK08991 MUS81; crossover junction endonuclease MUS81 [EC:3.1.22.-]"
					},
					{
						"name":"608719 SEM1; 26S proteasome complex subunit SEM1\tK10881 SHFM1; 26 proteasome complex subunit DSS1"
					},
					{
						"name":"102152833 SWI5; DNA repair protein SWI5 homolog\tK10991 SWI5; DNA repair protein Swi5\/Sae3"
					},
					{
						"name":"609700 SFR1; swi5-dependent recombination DNA repair protein 1 homolog isoform X2\tK10992 SFR1; Swi5-dependent recombination DNA repair protein 1"
					},
					{
						"name":"607780 SLX1A; structure-specific endonuclease subunit SLX1 isoform X2\tK15078 SLX1; structure-specific endonuclease subunit SLX1 [EC:3.6.1.-]"
					},
					{
						"name":"479867 SLX4; structure-specific endonuclease subunit SLX4\tK10484 BTBD12; structure-specific endonuclease subunit SLX4 (BTB\/POZ domain-containing protein 12)"
					},
					{
						"name":"482980 GEN1; flap endonuclease GEN homolog 1 isoform X2\tK15338 GEN1; holliday junction resolvase GEN1\/YEN1 [EC:3.1.-.-]"
					},
					{
						"name":"100856719 SPG11; spatacsin isoform X1\tK19026 SPG11; spatacsin"
					},
					{
						"name":"490745 ZFYVE26; zinc finger FYVE domain-containing protein 26 isoform X2\tK19027 ZFYVE26; zinc finger FYVE domain-containing protein 26"
					},
					{
						"name":"611768 RAD51AP1; RAD51-associated protein 1 isoform X1\tK20778 RAD51AP1; RAD51-associated protein 1"
					},
					{
						"name":"478944 NUCKS1; nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 isoform X1\tK28888 NUCKS1; nuclear ubiquitous casein and cyclin-dependent kinase substrate 1"
					},
					{
						"name":"610223 MORF4L1; mortality factor 4-like protein 1 isoform X1\tK11339 MORF4L1; mortality factor 4-like protein 1"
					},
					{
						"name":"485862 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 isoform X2\tK22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-]"
					},
					{
						"name":"483232 FIGNL1; fidgetin-like protein 1\tK22766 FIGNL1; fidgetin-like protein 1 [EC:5.6.2.-]"
					},
					{
						"name":"478694 SPIDR; DNA repair-scaffolding protein isoform X9\tK22806 SPIDR; DNA repair-scaffolding protein"
					},
					{
						"name":"102157178 LRATD2; protein LRATD2\tK22810 FAM84B; protein FAM84B"
					},
					{
						"name":"611424 CFAP410; cilia- and flagella-associated protein 410 isoform X1\tK23456 CFAP410; cilla- and flagella-associated protein"
					},
					{
						"name":"485036 HDGFL2; hepatoma-derived growth factor-related protein 2 isoform X1\tK25065 HDGFL2; hepatoma-derived growth factor-related protein 2"
					},
					{
						"name":"611130 SWSAP1; ATPase SWSAP1\tK25771 SWSAP1; ATPase SWSAP1"
					},
					{
						"name":"476800 EMSY; BRCA2-interacting transcriptional repressor EMSY isoform X41\tK25790 EMSY; BRCA2-interacting transcriptional repressor EMSY"
					},
					{
						"name":"611230 HSF2BP; heat shock factor 2-binding protein isoform X5\tK25791 HSF2BP; heat shock factor 2-binding protein"
					},
					{
						"name":"481930 MMS22L; protein MMS22-like isoform X1\tK26125 MMS22L; protein MMS22-like"
					},
					{
						"name":"475127 TONSL; tonsoku-like protein isoform X2\tK09257 NFKBIL2; NF-kappa-B inhibitor-like protein 2"
					},
					{
						"name":"479089 BOD1L1; biorientation of chromosomes in cell division protein 1-like 1 isoform X3\tK27262 BOD1L1; biorientation of chromosomes in cell division protein 1-like 1"
					},
					{
						"name":"612196 PARPBP; PCNA-interacting partner isoform X2\tK27412 PARPBP; PCNA-interacting partner"
					},
					{
						"name":"607087 HROB; homologous recombination OB-fold protein isoform X1\tK27803 HROB; homologous recombination OB-fold protein"
					},
					{
						"name":"477163 MCM8; DNA helicase MCM8\tK10737 MCM8; DNA helicase MCM8 [EC:5.6.2.4]"
					},
					{
						"name":"484104 MCM9; DNA helicase MCM9 isoform X3\tK10738 MCM9; DNA helicase MCM9 [EC:5.6.2.4]"
					},
					{
						"name":"476452 HNRNPUL1; heterogeneous nuclear ribonucleoprotein U-like protein 1 isoform X2\tK15047 HNRNPUL1; heterogeneous nuclear ribonucleoprotein U-like protein 1"
					},
					{
						"name":"476053 HNRNPUL2; heterogeneous nuclear ribonucleoprotein U-like protein 2\tK28611 HNRNPUL2; heterogeneous nuclear ribonucleoprotein U-like protein 2"
					},
					{
						"name":"607250 MRNIP; MRN complex-interacting protein isoform X1\tK28623 MRNIP; MRN complex-interacting protein"
					},
					{
						"name":"610266 RADX; RPA-related protein RADX isoform X1\tK29002 RADX; RPA-related protein RADX"
					},
					{
						"name":"608064 RBM6; RNA-binding protein 6 isoform X3\tK29038 RBM6; RNA-binding protein 6"
					}
					]
				}
				]
			},
			{
				"name":"NHEJ (non-homologous end-joining)",
				"children":[
				{
					"name":"DNA-PK complex",
					"children":[
					{
						"name":"474485 XRCC6; X-ray repair cross-complementing protein 6\tK10884 XRCC6; ATP-dependent DNA helicase 2 subunit 1"
					},
					{
						"name":"478902 XRCC5; X-ray repair cross-complementing protein 5\tK10885 XRCC5; ATP-dependent DNA helicase 2 subunit 2"
					},
					{
						"name":"474176 PRKDC; DNA-dependent protein kinase catalytic subunit\tK06642 PRKDC; DNA-dependent protein kinase catalytic subunit [EC:2.7.11.1]"
					}
					]
				},
				{
					"name":"MRX complex",
					"children":[
					{
						"name":"494006 MRE11; double-strand break repair protein MRE11 isoform X1\tK10865 MRE11; double-strand break repair protein MRE11"
					},
					{
						"name":"474674 RAD50; DNA repair protein RAD50 isoform X2\tK10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]"
					}
					]
				},
				{
					"name":"DNA Ligase 4 complex",
					"children":[
					{
						"name":"485544 LIG4; DNA ligase 4 isoform X2\tK10777 LIG4; DNA ligase 4 [EC:6.5.1.1]"
					},
					{
						"name":"488923 XRCC4; DNA repair protein XRCC4 isoform X1\tK10886 XRCC4; DNA-repair protein XRCC4"
					},
					{
						"name":"610570 NHEJ1; non-homologous end-joining factor 1\tK10980 NHEJ1; non-homologous end-joining factor 1"
					}
					]
				},
				{
					"name":"X-family DNA polymerases",
					"children":[
					{
						"name":"608341 POLL; DNA polymerase lambda isoform X2\tK03512 POLL; DNA polymerase lambda [EC:2.7.7.7 4.2.99.-]"
					},
					{
						"name":"100685589 POLM; DNA-directed DNA\/RNA polymerase mu isoform X1\tK03513 POLM; DNA polymerase mu [EC:2.7.7.7]"
					},
					{
						"name":"486815 DNTT; DNA nucleotidylexotransferase isoform X1\tK00977 DNTT; DNA nucleotidylexotransferase [EC:2.7.7.31]"
					},
					{
						"name":"494001 POLB; DNA polymerase beta isoform X2\tK02330 POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-]"
					}
					]
				},
				{
					"name":"Other NHEJ factors",
					"children":[
					{
						"name":"442943 APTX; aprataxin\tK10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]"
					},
					{
						"name":"481405 APLF; aprataxin and PNK-like factor isoform X3\tK13295 APLF; aprataxin and PNK-like factor [EC:3.1.-.-]"
					},
					{
						"name":"487123 DCLRE1C; protein artemis isoform X1\tK10887 DCLRE1C; DNA cross-link repair 1C protein [EC:3.1.-.-]"
					},
					{
						"name":"478737 TDP2; tyrosyl-DNA phosphodiesterase 2\tK19619 TDP2; tyrosyl-DNA phosphodiesterase 2 [EC:3.1.4.-]"
					},
					{
						"name":"490535 SMCHD1; structural maintenance of chromosomes flexible hinge domain-containing protein 1 isoform X1\tK23113 SMCHD1; structural maintenance of chromosomes flexible hinge domain-containing protein 1"
					},
					{
						"name":"102152370 PWWP domain-containing DNA repair factor 3B-like\tK23386 PWWP3; PWWP domain-containing DNA repair factor 3"
					},
					{
						"name":"610246 PWWP3B; PWWP domain-containing DNA repair factor 3B\tK23386 PWWP3; PWWP domain-containing DNA repair factor 3"
					},
					{
						"name":"612320 PWWP3A; PWWP domain-containing DNA repair factor 3A isoform X1\tK23386 PWWP3; PWWP domain-containing DNA repair factor 3"
					},
					{
						"name":"480670 PAXX; protein PAXX\tK25772 PAXX; protein PAXX"
					},
					{
						"name":"610293 CYREN; cell cycle regulator of non-homologous end joining isoform X1\tK26155 CYREN; cell cycle regulator of non-homologous end joining"
					},
					{
						"name":"490091 JMJD8; jmjC domain-containing protein 8 isoform X1\tK25792 JMJD8; jumonji domain-containing protein 8"
					},
					{
						"name":"100855997 SHLD1; shieldin complex subunit 1 isoform X1\tK26128 SHLD1; shieldin complex subunit 1"
					},
					{
						"name":"100683609 SHLD2; LOW QUALITY PROTEIN: shieldin complex subunit 2 isoform X3\tK26129 SHLD2; shieldin complex subunit 2"
					},
					{
						"name":"119870270 SHLD3; shieldin complex subunit 3\tK26130 SHLD3; shieldin complex subunit 3"
					},
					{
						"name":"482119 BEND4; BEN domain-containing protein 4 isoform X1\tK27845 BEND4; BEN domain-containing protein 4"
					},
					{
						"name":"100688342 IFFO2; intermediate filament family orphan 2\tK28738 IFFO; non-homologous end joining factor IFFO"
					},
					{
						"name":"486725 IFFO1; intermediate filament family orphan 1 isoform X2\tK28738 IFFO; non-homologous end joining factor IFFO"
					}
					]
				}
				]
			},
			{
				"name":"FA (Fanconi anemia) pathway",
				"children":[
				{
					"name":"FA core complex",
					"children":[
					{
						"name":"608713 FANCA; Fanconi anemia group A protein isoform X7\tK10888 FANCA; fanconi anemia group A protein"
					},
					{
						"name":"100687493 FANCB; Fanconi anemia group B protein\tK10889 FANCB; fanconi anemia group B protein"
					},
					{
						"name":"607277 FANCC; Fanconi anemia group C protein isoform X3\tK10890 FANCC; fanconi anemia group C protein"
					},
					{
						"name":"100856274 FANCE; Fanconi anemia group E protein isoform X1\tK10892 FANCE; fanconi anemia group E protein"
					},
					{
						"name":"102152851 FANCF; Fanconi anemia group F protein isoform X3\tK10893 FANCF; fanconi anemia group F protein"
					},
					{
						"name":"611887 FANCG; Fanconi anemia group G protein\tK10894 FANCG; fanconi anemia group G protein"
					},
					{
						"name":"612161 FANCL; E3 ubiquitin-protein ligase FANCL isoform X5\tK10606 FANCL; E3 ubiquitin-protein ligase FANCL [EC:2.3.2.27]"
					},
					{
						"name":"480307 FANCM; Fanconi anemia group M protein\tK10896 FANCM; fanconi anemia group M protein"
					},
					{
						"name":"476496 FAAP24; Fanconi anemia core complex-associated protein 24 isoform X3\tK10898 FAAP24; fanconi anemia-associated protein"
					},
					{
						"name":"608134 FAAP100; Fanconi anemia core complex-associated protein 100 isoform X1\tK10993 FAAP100; fanconi anemia core complex 100 kDa subunit"
					}
					]
				},
				{
					"name":"FA core complex binding factors",
					"children":[
					{
						"name":"119865321 HES1; transcription factor HES-1\tK06054 HES1; hairy and enhancer of split 1"
					},
					{
						"name":"487450 CENPS; centromere protein S\tK11511 APITD1; centromere protein S"
					},
					{
						"name":"119873204 CENPX; centromere protein X isoform X1\tK15360 STRA13; centromere protein X"
					},
					{
						"name":"607154 UBE2T; ubiquitin-conjugating enzyme E2 T\tK13960 UBE2T; ubiquitin-conjugating enzyme E2 T [EC:2.3.2.23]"
					}
					]
				},
				{
					"name":"Bloom's syndrome complex (BTR)",
					"children":[
					{
						"name":"100685609 BLM; Bloom syndrome protein isoform X2\tK10901 BLM; bloom syndrome protein [EC:5.6.2.4]"
					},
					{
						"name":"477576 TOP3B; DNA topoisomerase 3-beta-1 isoform X1\tK03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]"
					},
					{
						"name":"489537 TOP3A; DNA topoisomerase 3-alpha\tK03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]"
					},
					{
						"name":"100684392 RMI1; recQ-mediated genome instability protein 1 isoform X1\tK10990 RMI1; RecQ-mediated genome instability protein 1"
					},
					{
						"name":"609907 RMI2; recQ-mediated genome instability protein 2\tK15365 RMI2; RecQ-mediated genome instability protein 2"
					}
					]
				},
				{
					"name":"FANCD2-I complex",
					"children":[
					{
						"name":"484659 FANCD2; Fanconi anemia group D2 protein isoform X1\tK10891 FANCD2; fanconi anemia group D2 protein"
					},
					{
						"name":"100856370 FANCI; Fanconi anemia group I protein isoform X1\tK10895 FANCI; fanconi anemia group I protein"
					}
					]
				},
				{
					"name":"Downstream FA components",
					"children":[
					{
						"name":"403437 BRCA1; breast cancer type 1 susceptibility protein homolog\tK10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]"
					},
					{
						"name":"474180 BRCA2; breast cancer type 2 susceptibility protein\tK08775 BRCA2; breast cancer 2 susceptibility protein"
					},
					{
						"name":"491122 BRIP1; Fanconi anemia group J protein\tK15362 BRIP1; fanconi anemia group J protein [EC:5.6.2.3]"
					},
					{
						"name":"608527 PALB2; partner and localizer of BRCA2\tK10897 PALB2; partner and localizer of BRCA2"
					}
					]
				},
				{
					"name":"Other FA pathway factors",
					"children":[
					{
						"name":"479017 FAN1; fanconi-associated nuclease 1 isoform X1\tK15363 FAN1; fanconi-associated nuclease 1 [EC:3.1.21.- 3.1.4.1]"
					},
					{
						"name":"403568 RAD51; DNA repair protein RAD51 homolog 1\tK04482 RAD51; DNA repair protein RAD51"
					},
					{
						"name":"480573 RAD51C; DNA repair protein RAD51 homolog 3 isoform X1\tK10870 RAD51L2; RAD51-like protein 2"
					},
					{
						"name":"490076 TELO2; telomere length regulation protein TEL2 homolog isoform X1\tK11137 TELO2; telomere length regulation protein"
					},
					{
						"name":"479549 USP1; ubiquitin carboxyl-terminal hydrolase 1 isoform X1\tK11832 USP1; ubiquitin carboxyl-terminal hydrolase 1 [EC:3.4.19.12]"
					},
					{
						"name":"477027 WDR48; WD repeat-containing protein 48\tK15361 WDR48; WD repeat-containing protein 48"
					}
					]
				}
				]
			},
			{
				"name":"Other DSBR factors",
				"children":[
				{
					"name":"Protein phosphatase 6",
					"children":[
					{
						"name":"608922 PPP6C; serine\/threonine-protein phosphatase 6 catalytic subunit\tK15498 PPP6C; serine\/threonine-protein phosphatase 6 catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"484298 PPP6R1; serine\/threonine-protein phosphatase 6 regulatory subunit 1 isoform X8\tK15499 PPP6R1; serine\/threonine-protein phosphatase 6 regulatory subunit 1"
					},
					{
						"name":"481191 PPP6R2; serine\/threonine-protein phosphatase 6 regulatory subunit 2 isoform X2\tK15500 PPP6R2; serine\/threonine-protein phosphatase 6 regulatory subunit 2"
					},
					{
						"name":"483688 PPP6R3; serine\/threonine-protein phosphatase 6 regulatory subunit 3 isoform X1\tK15501 PPP6R3; serine\/threonine-protein phosphatase 6 regulatory subunit 3"
					},
					{
						"name":"477058 ANKRD28; serine\/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X5\tK15502 ANKRD28; serine\/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A"
					},
					{
						"name":"478852 ANKRD44; serine\/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B isoform X4\tK15503 ANKRD44; serine\/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B"
					},
					{
						"name":"481109 ANKRD52; serine\/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C isoform X1\tK15504 ANKRD52; serine\/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C"
					}
					]
				},
				{
					"name":"Ubiquitin ligases",
					"children":[
					{
						"name":"481775 RNF8; E3 ubiquitin-protein ligase RNF8\tK10667 RNF8; E3 ubiquitin-protein ligase RNF8 [EC:2.3.2.27]"
					},
					{
						"name":"488029 RNF168; E3 ubiquitin-protein ligase RNF168\tK20779 RNF168; E3 ubiquitin-protein ligase RNF168 [EC:2.3.2.31]"
					},
					{
						"name":"609300 RNF169; E3 ubiquitin-protein ligase RNF169\tK20805 RNF169; E3 ubiquitin-protein ligase RNF169 [EC:2.3.2.31]"
					},
					{
						"name":"479005 HERC2; E3 ubiquitin-protein ligase HERC2 isoform X2\tK10595 HERC2; E3 ubiquitin-protein ligase HERC2 [EC:2.3.2.26]"
					}
					]
				},
				{
					"name":"Others",
					"children":[
					{
						"name":"607892 WRAP53; LOW QUALITY PROTEIN: telomerase Cajal body protein 1\tK23314 WRAP53; telomerase Cajal body protein 1"
					},
					{
						"name":"119873341 TPRN; taperin\tK24164 TPRN; taperin"
					},
					{
						"name":"489840 ZCWPW1; zinc finger CW-type PWWP domain protein 1 isoform X8\tK24688 ZCWPW1; zinc finger CW-type PWWP domain protein 1"
					},
					{
						"name":"489225 WDR70; WD repeat-containing protein 70 isoform X3\tK24752 WDR70; WD repeat-containing protein 70"
					},
					{
						"name":"487529 WDR76; WD repeat-containing protein 76 isoform X3\tK24755 WDR76; WD repeat-containing protein 76"
					},
					{
						"name":"484628 HMCES; abasic site processing protein HMCES\tK28434 HMCES; abasic site processing protein HMCES"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"TLS (translesion DNA synthesis) factors",
			"children":[
			{
				"name":"Y-family DNA polymerases",
				"children":[
				{
					"name":"474915 POLH; DNA polymerase eta isoform X3\tK03509 POLH; DNA polymerase eta [EC:2.7.7.7]"
				},
				{
					"name":"100683243 POLI; DNA polymerase iota isoform X3\tK03510 POLI; DNA polymerase iota [EC:2.7.7.7]"
				},
				{
					"name":"479180 POLK; DNA polymerase kappa isoform X1\tK03511 POLK; DNA polymerase kappa [EC:2.7.7.7]"
				},
				{
					"name":"481337 REV1; DNA repair protein REV1 isoform X4\tK03515 REV1; DNA repair protein REV1 [EC:2.7.7.-]"
				}
				]
			},
			{
				"name":"B-family DNA polymerases",
				"children":[
				{
					"name":"481963 REV3L; DNA polymerase zeta catalytic subunit isoform X1\tK02350 REV3L; DNA polymerase zeta [EC:2.7.7.7]"
				}
				]
			},
			{
				"name":"A-family DNA polymerase",
				"children":[
				{
					"name":"488804 POLN; DNA polymerase nu isoform X1\tK16618 POLN; DNA polymerase nu [EC:2.7.7.7]"
				}
				]
			},
			{
				"name":"Rad6 epistasis group",
				"children":[
				{
					"name":"119870395 ubiquitin-conjugating enzyme E2 A-like\tK10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]"
				},
				{
					"name":"492095 UBE2A; ubiquitin-conjugating enzyme E2 A\tK10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]"
				},
				{
					"name":"100856010 ubiquitin-conjugating enzyme E2 B-like isoform X2\tK10574 UBE2B; ubiquitin-conjugating enzyme E2 B [EC:2.3.2.23]"
				},
				{
					"name":"474683 UBE2B; ubiquitin-conjugating enzyme E2 B\tK10574 UBE2B; ubiquitin-conjugating enzyme E2 B [EC:2.3.2.23]"
				},
				{
					"name":"476544 RAD18; LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase RAD18 isoform X1\tK10627 RAD18; E3 ubiquitin-protein ligase RAD18 [EC:2.3.2.27]"
				},
				{
					"name":"477106 HLTF; helicase-like transcription factor isoform X4\tK15711 SMARCA3; SWI\/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A3 [EC:5.6.2. 2.3.2.27]"
				},
				{
					"name":"100538347 UBE2V1; ubiquitin-conjugating enzyme E2 variant 1\tK10704 UBE2V; ubiquitin-conjugating enzyme E2 variant"
				},
				{
					"name":"119868036 ubiquitin-conjugating enzyme E2 variant 2\tK10704 UBE2V; ubiquitin-conjugating enzyme E2 variant"
				},
				{
					"name":"608470 UBE2V2; ubiquitin-conjugating enzyme E2 variant 2\tK10704 UBE2V; ubiquitin-conjugating enzyme E2 variant"
				},
				{
					"name":"100684029 ubiquitin-conjugating enzyme E2 N-like isoform X4\tK10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]"
				},
				{
					"name":"106558148 LOW QUALITY PROTEIN: ubiquitin-conjugating enzyme E2 N-like\tK10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]"
				},
				{
					"name":"111094434 LOW QUALITY PROTEIN: ubiquitin-conjugating enzyme E2 N-like\tK10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]"
				},
				{
					"name":"119863875 ubiquitin-conjugating enzyme E2 N-like\tK10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]"
				},
				{
					"name":"476784 ubiquitin-conjugating enzyme E2 N-like\tK10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]"
				},
				{
					"name":"479932 ubiquitin-conjugating enzyme E2 N-like isoform X2\tK10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]"
				},
				{
					"name":"607817 ubiquitin-conjugating enzyme E2 N-like\tK10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]"
				},
				{
					"name":"607889 ubiquitin-conjugating enzyme E2 N-like\tK10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]"
				},
				{
					"name":"608680 ubiquitin-conjugating enzyme E2 N-like isoform X2\tK10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]"
				},
				{
					"name":"609108 ubiquitin-conjugating enzyme E2 N-like\tK10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]"
				},
				{
					"name":"609637 ubiquitin-conjugating enzyme E2 N-like\tK10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]"
				},
				{
					"name":"610206 ubiquitin-conjugating enzyme E2 N\tK10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]"
				},
				{
					"name":"611801 ubiquitin-conjugating enzyme E2 N-like\tK10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]"
				},
				{
					"name":"611865 UBE2N; ubiquitin-conjugating enzyme E2 N\tK10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]"
				}
				]
			},
			{
				"name":"Other TLS factors",
				"children":[
				{
					"name":"477166 PCNA; proliferating cell nuclear antigen\tK04802 PCNA; proliferating cell nuclear antigen"
				},
				{
					"name":"106557458 PCLAF; PCNA-associated factor isoform X3\tK28763 PCLAF; PCNA-associated factor"
				},
				{
					"name":"612196 PARPBP; PCNA-interacting partner isoform X2\tK27412 PARPBP; PCNA-interacting partner"
				},
				{
					"name":"488972 SPRTN; DNA-dependent metalloprotease SPRTN isoform X2\tK24051 SPRTN; SprT-like domain-contaning protein Spartan"
				},
				{
					"name":"102154564 GCNA; acidic repeat-containing protein isoform X1\tK26957 GCNA; germ cell nuclear acidic protein"
				},
				{
					"name":"100856772 DPPA5; developmental pluripotency-associated 5 protein isoform X2\tK28975 DPPA5; developmental pluripotency-associated protein 5"
				}
				]
			}
			]
		},
		{
			"name":"Check point factors",
			"children":[
			{
				"name":"Rad9-Hus1-Rad1 complex",
				"children":[
				{
					"name":"483696 RAD9A; cell cycle checkpoint control protein RAD9A isoform X1\tK10994 RAD9A; cell cycle checkpoint control protein RAD9A [EC:3.1.11.2]"
				},
				{
					"name":"100855506 RAD9B; cell cycle checkpoint control protein RAD9B isoform X1\tK10995 RAD9B; cell cycle checkpoint control protein RAD9B"
				},
				{
					"name":"606789 HUS1; checkpoint protein HUS1 isoform X10\tK10903 HUS1; HUS1 checkpoint protein"
				},
				{
					"name":"479366 RAD1; cell cycle checkpoint protein RAD1 isoform X4\tK02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]"
				}
				]
			},
			{
				"name":"HRAD17(Rad24)-RFC complex",
				"children":[
				{
					"name":"478088 RAD17; cell cycle checkpoint protein RAD17\tK06662 HRAD17; cell cycle checkpoint protein"
				},
				{
					"name":"478667 RFC4; replication factor C subunit 4 isoform X1\tK10755 RFC2_4; replication factor C subunit 2\/4"
				},
				{
					"name":"489798 RFC2; replication factor C subunit 2 isoform X1\tK10755 RFC2_4; replication factor C subunit 2\/4"
				},
				{
					"name":"477308 RFC3; replication factor C subunit 3 isoform X2\tK10756 RFC3_5; replication factor C subunit 3\/5"
				},
				{
					"name":"477499 RFC5; replication factor C subunit 5 isoform X2\tK10756 RFC3_5; replication factor C subunit 3\/5"
				}
				]
			},
			{
				"name":"Rad17-Mec3-Ddc1 complex",
				"children":[
				{
					"name":"479366 RAD1; cell cycle checkpoint protein RAD1 isoform X4\tK02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]"
				}
				]
			},
			{
				"name":"FPC (fork protection complex)",
				"children":[
				{
					"name":"481112 TIMELESS; protein timeless homolog isoform X1\tK10997 TIMELESS; replication fork protection complex subunit TIMELESS\/Tof1\/Swi1"
				},
				{
					"name":"100683743 TIPIN; TIMELESS-interacting protein\tK10998 TIPIN; replication fork protection complex subunit TIPIN\/Csm3\/Swi3"
				},
				{
					"name":"482481 CLSPN; claspin\tK25773 CLSPN; claspin"
				}
				]
			},
			{
				"name":"Triple T complex",
				"children":[
				{
					"name":"490076 TELO2; telomere length regulation protein TEL2 homolog isoform X1\tK11137 TELO2; telomere length regulation protein"
				},
				{
					"name":"477225 TTI1; TELO2-interacting protein 1 homolog isoform X2\tK20403 TTI1; TELO2-interacting protein 1"
				},
				{
					"name":"608405 TTI2; LOW QUALITY PROTEIN: TELO2-interacting protein 2 isoform X1\tK23115 TTI2; TELO2-interacting protein 2"
				}
				]
			},
			{
				"name":"BAG6-UBL4A-GET4 complex",
				"children":[
				{
					"name":"474842 BAG6; large proline-rich protein BAG6 isoform X17\tK23390 BAG6; large proline-rich protein BAG6"
				},
				{
					"name":"100856125 UBL4B; ubiquitin-like protein 4B\tK23388 UBL4; ubiquitin-like protein 4"
				},
				{
					"name":"491599 GET4; Golgi to ER traffic protein 4 homolog isoform X3\tK23387 GET4; golgi to ER traffic protein 4"
				}
				]
			},
			{
				"name":"SOSS complex",
				"children":[
				{
					"name":"100855813 INTS3; integrator complex subunit 3 isoform X2\tK13140 INTS3; integrator complex subunit 3 (SOSS complex subunit A)"
				},
				{
					"name":"474400 NABP2; SOSS complex subunit B1\tK28889 NABP; SOSS complex subunit B"
				},
				{
					"name":"478847 NABP1; SOSS complex subunit B2 isoform X1\tK28889 NABP; SOSS complex subunit B"
				},
				{
					"name":"481671 INIP; SOSS complex subunit C isoform X1\tK28890 INIP; SOSS complex subunit C"
				}
				]
			},
			{
				"name":"Other check point factors",
				"children":[
				{
					"name":"100856315 ATR; serine\/threonine-protein kinase ATR isoform X1\tK06640 ATR; serine\/threonine-protein kinase ATR [EC:2.7.11.1]"
				},
				{
					"name":"608504 ATRIP; ATR-interacting protein isoform X1\tK10905 ATRIP; ATR interacting protein"
				},
				{
					"name":"474621 ETAA1; ewing's tumor-associated antigen 1 isoform X3\tK28856 ETAA1; Ewing's tumor-associated antigen 1"
				},
				{
					"name":"479450 ATM; serine-protein kinase ATM\tK04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]"
				},
				{
					"name":"403869 TP53; cellular tumor antigen p53\tK04451 TP53; tumor protein p53"
				},
				{
					"name":"609767 CHEK1; serine\/threonine-protein kinase Chk1 isoform X8\tK02216 CHEK1; serine\/threonine-protein kinase CHEK1 [EC:2.7.11.1]"
				},
				{
					"name":"486338 CHEK2; serine\/threonine-protein kinase Chk2 isoform X3\tK06641 CHEK2; serine\/threonine-protein kinase CHEK2 [EC:2.7.11.1]"
				},
				{
					"name":"484780 CDC25A; M-phase inducer phosphatase 1\tK06645 CDC25A; M-phase inducer phosphatase 1 [EC:3.1.3.48]"
				},
				{
					"name":"485790 CDC25B; M-phase inducer phosphatase 2 isoform X1\tK05866 CDC25B; M-phase inducer phosphatase 2 [EC:3.1.3.48]"
				},
				{
					"name":"610456 CDC25C; M-phase inducer phosphatase 3 isoform X3\tK05867 CDC25C; M-phase inducer phosphatase 3 [EC:3.1.3.48]"
				},
				{
					"name":"100855903 14-3-3 protein zeta\/delta-like isoform X3\tK16197 YWHAB_Q_Z; 14-3-3 protein beta\/theta\/zeta"
				},
				{
					"name":"475864 YWHAZ; 14-3-3 protein zeta\/delta\tK16197 YWHAB_Q_Z; 14-3-3 protein beta\/theta\/zeta"
				},
				{
					"name":"477237 YWHAB; 14-3-3 protein beta\/alpha\tK16197 YWHAB_Q_Z; 14-3-3 protein beta\/theta\/zeta"
				},
				{
					"name":"479459 LOW QUALITY PROTEIN: 14-3-3 protein theta-like\tK16197 YWHAB_Q_Z; 14-3-3 protein beta\/theta\/zeta"
				},
				{
					"name":"607060 YWHAQ; 14-3-3 protein theta\tK16197 YWHAB_Q_Z; 14-3-3 protein beta\/theta\/zeta"
				},
				{
					"name":"609669 LOW QUALITY PROTEIN: 14-3-3 protein zeta\/delta-like\tK16197 YWHAB_Q_Z; 14-3-3 protein beta\/theta\/zeta"
				},
				{
					"name":"100687866 YWHAH; 14-3-3 protein eta\tK16198 YWHAG_H; 14-3-3 protein gamma\/eta"
				},
				{
					"name":"489818 YWHAG; 14-3-3 protein gamma\tK16198 YWHAG_H; 14-3-3 protein gamma\/eta"
				},
				{
					"name":"480645 YWHAE; 14-3-3 protein epsilon isoform X2\tK06630 YWHAE; 14-3-3 protein epsilon"
				},
				{
					"name":"608573 LOW QUALITY PROTEIN: 14-3-3 protein epsilon-like\tK06630 YWHAE; 14-3-3 protein epsilon"
				},
				{
					"name":"485411 NAV2; neuron navigator 2 isoform X6\tK19483 NAV2; neuron navigator 2 [EC:5.6.2.4]"
				},
				{
					"name":"475525 WEE2; wee1-like protein kinase 2\tK06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]"
				},
				{
					"name":"476847 WEE1; wee1-like protein kinase isoform X1\tK06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]"
				},
				{
					"name":"489488 PER1; period circadian protein homolog 1\tK21944 PER1; period circadian protein 1"
				},
				{
					"name":"486180 PER2; period circadian protein homolog 2\tK02633 PER2; period circadian protein 2"
				},
				{
					"name":"608256 PER3; period circadian protein homolog 3 isoform X1\tK21945 PER3; period circadian protein 3"
				},
				{
					"name":"100855462 MDC1; mediator of DNA damage checkpoint protein 1 isoform X2\tK20780 MDC1; mediator of DNA damage checkpoint protein 1"
				},
				{
					"name":"481025 PLS3; plastin-3\tK17336 PLS3; plastin-3"
				},
				{
					"name":"488728 AEN; apoptosis-enhancing nuclease isoform X1\tK18340 AEN; apoptosis-enhancing nuclease [EC:3.1.-.-]"
				},
				{
					"name":"475380 PLK3; serine\/threonine-protein kinase PLK3\tK08862 PLK3; polo-like kinase 3 [EC:2.7.11.21]"
				},
				{
					"name":"485081 PLK5; LOW QUALITY PROTEIN: inactive serine\/threonine-protein kinase PLK5 isoform X5\tK19596 PLK5; inactive serine\/threonine-protein kinase PLK5"
				},
				{
					"name":"100683905 NEK5; LOW QUALITY PROTEIN: serine\/threonine-protein kinase Nek5 isoform X5\tK08857 NEK1_4_5; serine\/threonine-protein kinase Nek1\/4\/5 [EC:2.7.11.1]"
				},
				{
					"name":"476591 NEK4; serine\/threonine-protein kinase Nek4 isoform X4\tK08857 NEK1_4_5; serine\/threonine-protein kinase Nek1\/4\/5 [EC:2.7.11.1]"
				},
				{
					"name":"486058 NEK1; LOW QUALITY PROTEIN: serine\/threonine-protein kinase Nek1 isoform X1\tK08857 NEK1_4_5; serine\/threonine-protein kinase Nek1\/4\/5 [EC:2.7.11.1]"
				},
				{
					"name":"485638 NEK10; serine\/threonine-protein kinase Nek10 isoform X1\tK20879 NEK10; serine\/threonine-protein kinase Nek10 [EC:2.7.11.1]"
				},
				{
					"name":"485660 NEK11; serine\/threonine-protein kinase Nek11 isoform X1\tK20880 NEK11; serine\/threonine-protein kinase Nek11 [EC:2.7.11.1]"
				},
				{
					"name":"100856622 DONSON; protein downstream neighbor of Son isoform X1\tK22422 DONSON; protein downstream neighbor of Son"
				},
				{
					"name":"100682578 KANK2; KN motif and ankyrin repeat domain-containing protein 2\tK22808 KANK; KN motif and ankyrin repeat domain-containing protein"
				},
				{
					"name":"100684819 KANK4; KN motif and ankyrin repeat domain-containing protein 4\tK22808 KANK; KN motif and ankyrin repeat domain-containing protein"
				},
				{
					"name":"100687276 KANK1; KN motif and ankyrin repeat domain-containing protein 1 isoform X1\tK22808 KANK; KN motif and ankyrin repeat domain-containing protein"
				},
				{
					"name":"476723 KANK3; KN motif and ankyrin repeat domain-containing protein 3 isoform X5\tK22808 KANK; KN motif and ankyrin repeat domain-containing protein"
				},
				{
					"name":"477926 CHMP4C; charged multivesicular body protein 4c\tK24782 CHMP4C; charged multivesicular body protein 4C"
				},
				{
					"name":"479674 VPS4A; vacuolar protein sorting-associated protein 4A isoform X2\tK12196 VPS4; vacuolar protein-sorting-associated protein 4"
				},
				{
					"name":"607306 VPS4B; vacuolar protein sorting-associated protein 4B\tK12196 VPS4; vacuolar protein-sorting-associated protein 4"
				},
				{
					"name":"100855483 ZFYVE19; abscission\/NoCut checkpoint regulator\tK24778 ZFYVE19; abscission\/NoCut checkpoint regulator"
				},
				{
					"name":"480111 SDE2; replication stress response regulator SDE2 isoform X2\tK25059 SDE2; replication stress response regulator SDE2"
				},
				{
					"name":"475759 KRCC1; lysine-rich coiled-coil protein 1\tK29003 KRCC1; lysine-rich coiled-coil protein 1"
				},
				{
					"name":"100685444 BLCAP; bladder cancer-associated protein\tK29062 BLCAP; apoptosis inducing factor BLCAP"
				}
				]
			}
			]
		},
		{
			"name":"Other factors with a suspected DNA repair function",
			"children":[
			{
				"name":"DNA polymerases",
				"children":[
				{
					"name":"488003 POLQ; DNA polymerase theta isoform X2\tK02349 POLQ; DNA polymerase theta [EC:2.7.7.7]"
				},
				{
					"name":"489442 MYBBP1A; myb-binding protein 1A isoform X1\tK02331 POL5; DNA polymerase phi [EC:2.7.7.7]"
				},
				{
					"name":"475632 PRIMPOL; DNA-directed primase\/polymerase protein isoform X1\tK22761 PRIMPOL; DNA-directed primase\/polymerase protein [EC:2.7.7.102 2.7.7.7]"
				}
				]
			},
			{
				"name":"Nucleases",
				"children":[
				{
					"name":"102155466 TREX1; three-prime repair exonuclease 1 isoform X1\tK10790 TREX1; three prime repair exonuclease 1 [EC:3.1.11.2]"
				},
				{
					"name":"492236 TREX2; three prime repair exonuclease 2\tK10791 TREX2; three prime repair exonuclease 2 [EC:3.1.11.2]"
				},
				{
					"name":"477824 DCLRE1A; DNA cross-link repair 1A protein\tK15340 DCLRE1A; DNA cross-link repair 1A protein"
				},
				{
					"name":"606778 DCLRE1B; 5' exonuclease Apollo isoform X2\tK15341 DCLRE1B; DNA cross-link repair 1B protein [EC:3.1.-.-]"
				},
				{
					"name":"475314 EXO5; exonuclease V isoform X3\tK17815 EXO5; exonuclease V [EC:3.1.-.-]"
				},
				{
					"name":"608430 ENDOV; endonuclease V isoform X1\tK21813 ENDOV; endonuclease V [EC:3.1.26.-]"
				},
				{
					"name":"476128 ZRANB3; DNA annealing helicase and endonuclease ZRANB3 isoform X1\tK25861 ZRANB3; DNA annealing helicase and endonuclease ZRANB3 [EC:5.6.2.- 3.1.-.-]"
				},
				{
					"name":"610155 ANKLE1; ankyrin repeat and LEM domain-containing protein 1\tK21411 ANKLE1; ankyrin repeat and LEM domain-containing protein 1"
				}
				]
			},
			{
				"name":"Helicases",
				"children":[
				{
					"name":"487837 HELQ; helicase POLQ-like isoform X2\tK19178 HELQ; POLQ-like helicase [EC:5.6.2.4]"
				},
				{
					"name":"476297 ERCC6L2; DNA excision repair protein ERCC-6-like 2 isoform X1\tK20098 ERCC6L2; DNA excision repair protein ERCC-6-like 2 [EC:5.6.2.-]"
				}
				]
			},
			{
				"name":"PSO4 complex",
				"children":[
				{
					"name":"611552 PRPF19; pre-mRNA-processing factor 19 isoform X1\tK10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]"
				},
				{
					"name":"474921 CDC5L; cell division cycle 5-like protein\tK12860 CDC5L; pre-mRNA-splicing factor CDC5\/CEF1"
				},
				{
					"name":"475805 BCAS2; pre-mRNA-splicing factor SPF27 isoform X2\tK12861 BCAS2; pre-mRNA-splicing factor SPF27"
				},
				{
					"name":"612490 PLRG1; pleiotropic regulator 1 isoform X1\tK12862 PLRG1; pleiotropic regulator 1"
				}
				]
			},
			{
				"name":"Modulation of nucleotide pools",
				"children":[
				{
					"name":"100685818 NUDT15; nucleotide triphosphate diphosphatase NUDT15\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]"
				},
				{
					"name":"489894 NUDT1; 7,8-dihydro-8-oxoguanine triphosphatase\tK17816 NUDT1; 8-oxo-dGTP diphosphatase \/ 2-hydroxy-dATP diphosphatase [EC:3.6.1.55 3.6.1.56]"
				},
				{
					"name":"609139 NUDT18; 8-oxo-dGDP phosphatase NUDT18 isoform X2\tK17817 NUDT18; 8-oxo-dGDP phosphatase [EC:3.6.1.58]"
				},
				{
					"name":"609526 DUT; deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial\tK01520 dut; dUTP diphosphatase [EC:3.6.1.23]"
				},
				{
					"name":"476823 RRM1; ribonucleoside-diphosphate reductase large subunit isoform X2\tK10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]"
				},
				{
					"name":"481988 RRM2B; ribonucleoside-diphosphate reductase subunit M2 B isoform X4\tK10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]"
				},
				{
					"name":"482963 RRM2; ribonucleoside-diphosphate reductase subunit M2\tK10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic type",
		"children":[
		{
			"name":"SSBR (single strand breaks repair)",
			"children":[
			{
				"name":"Direct repair",
				"children":[
				{
					"name":"442978 MGMT; methylated-DNA--protein-cysteine methyltransferase\tK00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]"
				}
				]
			},
			{
				"name":"BER (base exicision repair)",
				"children":[
				{
					"name":"DNA glycosylases",
					"children":[
					{
						"name":"486315 UNG; uracil-DNA glycosylase\tK03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]"
					},
					{
						"name":"486497 SMUG1; single-strand selective monofunctional uracil DNA glycosylase isoform X1\tK10800 SMUG1; single-strand selective monofunctional uracil DNA glycosylase [EC:3.2.2.-]"
					},
					{
						"name":"611597 MPG; DNA-3-methyladenine glycosylase isoform X1\tK03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]"
					},
					{
						"name":"100856592 MUTYH; adenine DNA glycosylase isoform X7\tK03575 mutY; A\/G-specific adenine glycosylase [EC:3.2.2.31]"
					},
					{
						"name":"610981 NTHL1; endonuclease III-like protein 1 isoform X3\tK10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]"
					}
					]
				},
				{
					"name":"AP endonucleases"
				},
				{
					"name":"RecJ"
				},
				{
					"name":"DNA ligase"
				},
				{
					"name":"DNA polymerase I"
				}
				]
			},
			{
				"name":"NER (nucleotide excision repair)",
				"children":[
				{
					"name":"GGR (global genome repair) factors"
				},
				{
					"name":"TCR (transcription coupled repair) factors",
					"children":[
					{
						"name":"DNA-directed RNA polymerase complex (RNAP)"
					},
					{
						"name":"TRCF (transcription-repair coupling factor)"
					}
					]
				}
				]
			},
			{
				"name":"MMR (mismatch excision repair)",
				"children":[
				{
					"name":"Mismatch and loop recognition factors"
				},
				{
					"name":"Molecular matchmaker"
				},
				{
					"name":"Strand discrimination factor"
				},
				{
					"name":"DNA exonucleases"
				},
				{
					"name":"DNA polymerase III holoenzyme"
				},
				{
					"name":"DNA ligase"
				},
				{
					"name":"Other MMR factors",
					"children":[
					{
						"name":"475524 SSBP1; single-stranded DNA-binding protein, mitochondrial\tK03111 ssb; single-strand DNA-binding protein"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"DSBR (double strand breaks repair)",
			"children":[
			{
				"name":"HR (homologous recombination)",
				"children":[
				{
					"name":"RecBC pathway proteins"
				},
				{
					"name":"RecFOR pathway proteins"
				},
				{
					"name":"AddAB pathway proteins"
				},
				{
					"name":"Other HR factor"
				},
				{
					"name":"Archaeal homologous recombinant proteins"
				}
				]
			},
			{
				"name":"NHEJ (non-homologous end-joining)",
				"children":[
				{
					"name":"Two-component NHEJ DNA repair complex"
				},
				{
					"name":"SHIIR (short-homology-independent illegitimate recombination)",
					"children":[
					{
						"name":"Facilitator"
					},
					{
						"name":"Supressor"
					}
					]
				},
				{
					"name":"SHDIR (short-homology-dependent illegitimate recombination)",
					"children":[
					{
						"name":"RecET pathway"
					},
					{
						"name":"Facilitator"
					},
					{
						"name":"Supressor"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"TLS (translesion DNA synthesis) factors",
			"children":[
			{
				"name":"Y-family DNA polymerases"
			},
			{
				"name":"Other SOS response factors",
				"children":[
				{
					"name":"475524 SSBP1; single-stranded DNA-binding protein, mitochondrial\tK03111 ssb; single-strand DNA-binding protein"
				}
				]
			}
			]
		},
		{
			"name":"Other factors with a suspected DNA repair function",
			"children":[
			{
				"name":"DNA polymerase"
			},
			{
				"name":"DNA helicases"
			},
			{
				"name":"Modulation of nucleotide pools",
				"children":[
				{
					"name":"100685818 NUDT15; nucleotide triphosphate diphosphatase NUDT15\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]"
				},
				{
					"name":"609526 DUT; deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial\tK01520 dut; dUTP diphosphatase [EC:3.6.1.23]"
				}
				]
			},
			{
				"name":"Others"
			}
			]
		}
		]
	}
	]
}