{
	"name":"cgi03400",
	"children":[
	{
		"name":"Eukaryotic type",
		"children":[
		{
			"name":"SSBR (single strand breaks repair)",
			"children":[
			{
				"name":"Direct repair"
			},
			{
				"name":"BER (base exicision repair)",
				"children":[
				{
					"name":"DNA glycosylases",
					"children":[
					{
						"name":"CGB_A7690W uracil DNA N-glycosylase\tK03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]"
					},
					{
						"name":"CGB_F5460C hypothetical protein\tK20813 TDG; thymine-DNA glycosylase [EC:3.2.2.29]"
					},
					{
						"name":"CGB_B0690W A\/G-specific adenine DNA glycosylase\tK03575 mutY; A\/G-specific adenine glycosylase [EC:3.2.2.31]"
					},
					{
						"name":"CGB_B4250W purine-specific oxidized base lesion DNA N-glycosylase\tK03660 OGG1; N-glycosylase\/DNA lyase [EC:3.2.2.- 4.2.99.18]"
					},
					{
						"name":"CGB_G1430W DNA-(apurinic or apyrimidinic site) lyase\tK10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]"
					}
					]
				},
				{
					"name":"AP endonucleases",
					"children":[
					{
						"name":"CGB_L1330C DNA-(apurinic or apyrimidinic site) lyase\tK10771 APEX1; AP endonuclease 1 [EC:3.1.11.2]"
					},
					{
						"name":"CGB_H3800W DNA-(apurinic or apyrimidinic site) lyase\tK10772 APEX2; AP endonuclease 2 [EC:3.1.11.2]"
					}
					]
				},
				{
					"name":"Long Patch-BER factors",
					"children":[
					{
						"name":"DNA polymerase delta complex",
						"children":[
						{
							"name":"CGB_K3720C delta DNA polymerase\tK02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]"
						},
						{
							"name":"CGB_B8190W DNA polymerase delta, small subunit\tK02328 POLD2; DNA polymerase delta subunit 2"
						},
						{
							"name":"CGB_C9570W hypothetical protein\tK03504 POLD3; DNA polymerase delta subunit 3"
						},
						{
							"name":"CGB_L3530C hypothetical protein\tK03505 POLD4; DNA polymerase delta subunit 4"
						}
						]
					},
					{
						"name":"DNA polymerase epsilon complex",
						"children":[
						{
							"name":"CGB_K2570C DNA polymerase epsilon, catalytic subunit A\tK02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]"
						},
						{
							"name":"CGB_F1400C epsilon DNA polymerase\tK02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]"
						},
						{
							"name":"CGB_G1400W DNA polymerase epsilon p12 subunit (dna polymerase epsilon subunit 4)\tK03506 POLE4; DNA polymerase epsilon subunit 4 [EC:2.7.7.7]"
						}
						]
					},
					{
						"name":"CGB_M1090C DNA processivity factor; Pol30p\tK04802 PCNA; proliferating cell nuclear antigen"
					},
					{
						"name":"CGB_D3420W flap endonuclease\tK04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]"
					},
					{
						"name":"CGB_H3700W DNA ligase\tK10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]"
					}
					]
				},
				{
					"name":"Short Patch-BER factors"
				},
				{
					"name":"Other BER factors",
					"children":[
					{
						"name":"CGB_D5760W hypothetical protein\tK10862 TDP1; tyrosyl-DNA phosphodiesterase 1 [EC:3.1.4.-]"
					},
					{
						"name":"CGB_C7100C hypothetical protein\tK10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]"
					},
					{
						"name":"CGB_A9280C hypothetical protein\tK08073 PNKP; bifunctional polynucleotide phosphatase\/kinase [EC:3.1.3.32 2.7.1.78]"
					},
					{
						"name":"CGB_H2300W hypothetical protein\tK03512 POLL; DNA polymerase lambda [EC:2.7.7.7 4.2.99.-]"
					}
					]
				}
				]
			},
			{
				"name":"NER (nucleotide excision repair)",
				"children":[
				{
					"name":"GGR (global genome repair) factors",
					"children":[
					{
						"name":"XPC-HR23B-CETN2 complex",
						"children":[
						{
							"name":"CGB_D7540C hypothetical protein\tK10838 XPC; xeroderma pigmentosum group C-complementing protein"
						},
						{
							"name":"CGB_A8600W uv excision repair protein rhp23\tK10839 RAD23; UV excision repair protein RAD23"
						}
						]
					},
					{
						"name":"Cul4-DDB2 complex",
						"children":[
						{
							"name":"CGB_A3220W ubiquitin-protein ligase\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
						},
						{
							"name":"CGB_G0470C ubiquitin-protein ligase\tK10609 CUL4; cullin 4"
						},
						{
							"name":"CGB_G1120W hypothetical protein\tK10610 DDB1; DNA damage-binding protein 1"
						}
						]
					},
					{
						"name":"NER4 complex",
						"children":[
						{
							"name":"CGB_D3060W DNA dependent ATPase\tK15082 RAD7; DNA repair protein RAD7"
						},
						{
							"name":"CGB_E0440W DNA repair protein rad16\tK15083 RAD16; DNA repair protein RAD16"
						}
						]
					}
					]
				},
				{
					"name":"TCR (transcription coupled repair) factors",
					"children":[
					{
						"name":"DNA-directed RNA polymerase II complex",
						"children":[
						{
							"name":"CGB_E5020W DNA-directed RNA polymerase II largest subunit\tK03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]"
						},
						{
							"name":"CGB_D6240C DNA-dependent RNA polymerase II RPB140\tK03010 RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]"
						},
						{
							"name":"CGB_E6710C RNA polymerase II subunit 3\tK03011 RPB3; DNA-directed RNA polymerase II subunit RPB3"
						},
						{
							"name":"CGB_I1280W hypothetical protein\tK03012 RPB4; DNA-directed RNA polymerase II subunit RPB4"
						},
						{
							"name":"CGB_H2540C DNA-directed RNA polymerases I, II and III polypeptide\tK03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2"
						},
						{
							"name":"CGB_D7770C hypothetical protein\tK03015 RPB7; DNA-directed RNA polymerase II subunit RPB7"
						},
						{
							"name":"CGB_H3630W DNA-directed RNA polymerases I, II and III 17.1 kDapolypeptide\tK03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3"
						},
						{
							"name":"CGB_B5180W DNA-directed RNA polymerase II 13.3 kDa polypeptide\tK03008 RPB11; DNA-directed RNA polymerase II subunit RPB11"
						}
						]
					},
					{
						"name":"Cul4-CSA complex",
						"children":[
						{
							"name":"CGB_A3220W ubiquitin-protein ligase\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
						},
						{
							"name":"CGB_G0470C ubiquitin-protein ligase\tK10609 CUL4; cullin 4"
						},
						{
							"name":"CGB_G1120W hypothetical protein\tK10610 DDB1; DNA damage-binding protein 1"
						}
						]
					},
					{
						"name":"Other TCR factor",
						"children":[
						{
							"name":"CGB_A2190C cell growth-related protein\tK25829 ELOF1; transcription elongation factor 1"
						}
						]
					}
					]
				},
				{
					"name":"TFIIH complex",
					"children":[
					{
						"name":"CGB_A6410W general RNA polymerase II transcription factor\tK10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]"
					},
					{
						"name":"CGB_A6060C general RNA polymerase II transcription factor\tK10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]"
					},
					{
						"name":"CGB_C4580C hypothetical protein\tK03141 TFIIH1; transcription initiation factor TFIIH subunit 1"
					},
					{
						"name":"CGB_H2410W component of RNA polymerase transcription factor TFIIH; Ssl1p\tK03142 TFIIH2; transcription initiation factor TFIIH subunit 2"
					},
					{
						"name":"CGB_M0140C hypothetical protein\tK03143 TFIIH3; transcription initiation factor TFIIH subunit 3"
					},
					{
						"name":"CGB_N1600W subunit of TFIIH and nucleotide excision repair factor 3 complexes\tK03144 TFIIH4; transcription initiation factor TFIIH subunit 4"
					},
					{
						"name":"CGB_N2440W cyclin-dependent protein kinase\tK02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]"
					},
					{
						"name":"CGB_H2140W cyclin-dependent protein kinase regulator\tK06634 CCNH; cyclin H"
					},
					{
						"name":"CGB_F5340C transcription\/repair factor TFIIH subunit Tfb3\tK10842 MNAT1; CDK-activating kinase assembly factor MAT1"
					}
					]
				},
				{
					"name":"RPA (replication factor A)",
					"children":[
					{
						"name":"CGB_D5240W damaged DNA binding protein\tK07466 RFA1; replication factor A1"
					},
					{
						"name":"CGB_D7370C hypothetical protein\tK10739 RFA2; replication factor A2"
					},
					{
						"name":"CGB_A3320C single-stranded DNA binding protein 12k chain\tK10740 RPA3; replication factor A3"
					}
					]
				},
				{
					"name":"Other NER factors",
					"children":[
					{
						"name":"CGB_G4750W DNA repair protein RAD14\tK10847 XPA; DNA-repair protein complementing XP-A cells"
					},
					{
						"name":"CGB_F5210C mating-type switching protein swi10\tK10849 ERCC1; DNA excision repair protein ERCC-1"
					},
					{
						"name":"CGB_L2190W single-stranded DNA endonuclease; Rad1p\tK10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]"
					},
					{
						"name":"CGB_B3600W single-stranded DNA specific endodeoxyribonuclease\tK10846 ERCC5; DNA excision repair protein ERCC-5"
					},
					{
						"name":"CGB_H3700W DNA ligase\tK10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]"
					},
					{
						"name":"CGB_E1180W hypothetical protein\tK15075 MET18; DNA repair\/transcription protein MET18\/MMS19"
					},
					{
						"name":"CGB_F5010W transcription-related protein\tK26403 CIAO2; cytosolic iron-sulfur assembly component 2"
					},
					{
						"name":"CGB_G0120W ubiquitin-protein ligase\tK03869 CUL3; cullin 3"
					},
					{
						"name":"CGB_B3080W transcriptional elongation regulator\tK03872 ELOC; elongin-C"
					},
					{
						"name":"CGB_L1180W pof4 protein\tK15077 ELA1; elongin-A"
					}
					]
				}
				]
			},
			{
				"name":"MMR (mismatch excision repair)",
				"children":[
				{
					"name":"Mismatch and loop recognition factors",
					"children":[
					{
						"name":"CGB_A8580C DNA mismatch repair protein MSH2\tK08735 MSH2; DNA mismatch repair protein MSH2"
					},
					{
						"name":"CGB_C2370C hypothetical protein\tK08736 MSH3; DNA mismatch repair protein MSH3"
					},
					{
						"name":"CGB_K1250C DNA mismatch repair-related protein\tK08737 MSH6; DNA mismatch repair protein MSH6"
					}
					]
				},
				{
					"name":"MutL homologs",
					"children":[
					{
						"name":"CGB_E6200C MUTL-like protein 1\tK08734 MLH1; DNA mismatch repair protein MLH1"
					},
					{
						"name":"CGB_C3590W ATPase\tK10858 PMS2; DNA mismatch repair protein PMS2"
					},
					{
						"name":"CGB_D4110W mismatch repair-related protein\tK08739 MLH3; DNA mismatch repair protein MLH3"
					}
					]
				},
				{
					"name":"DNA polymerase delta complex",
					"children":[
					{
						"name":"CGB_K3720C delta DNA polymerase\tK02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]"
					},
					{
						"name":"CGB_B8190W DNA polymerase delta, small subunit\tK02328 POLD2; DNA polymerase delta subunit 2"
					},
					{
						"name":"CGB_C9570W hypothetical protein\tK03504 POLD3; DNA polymerase delta subunit 3"
					},
					{
						"name":"CGB_L3530C hypothetical protein\tK03505 POLD4; DNA polymerase delta subunit 4"
					}
					]
				},
				{
					"name":"RPA (replication factor A)",
					"children":[
					{
						"name":"CGB_D5240W damaged DNA binding protein\tK07466 RFA1; replication factor A1"
					},
					{
						"name":"CGB_D7370C hypothetical protein\tK10739 RFA2; replication factor A2"
					},
					{
						"name":"CGB_A3320C single-stranded DNA binding protein 12k chain\tK10740 RPA3; replication factor A3"
					}
					]
				},
				{
					"name":"RFC (replication factor C)",
					"children":[
					{
						"name":"CGB_K2700C DNA replication activator 1 subunit1 (Replication factor C subunit 1)\tK10754 RFC1; replication factor C subunit 1"
					},
					{
						"name":"CGB_G3360C subunit of heteropentameric Replication factor C (RF-C); Rfc3p\tK10755 RFC2_4; replication factor C subunit 2\/4"
					},
					{
						"name":"CGB_L0470C DNA replication factor (activator 1 subunit)\tK10755 RFC2_4; replication factor C subunit 2\/4"
					},
					{
						"name":"CGB_A1550C subunit of DNA Replication factor C (RF-C); Rfc5p\tK10756 RFC3_5; replication factor C subunit 3\/5"
					},
					{
						"name":"CGB_N0500W DNA replication factor\tK10756 RFC3_5; replication factor C subunit 3\/5"
					}
					]
				},
				{
					"name":"Other MMR factors",
					"children":[
					{
						"name":"CGB_M1090C DNA processivity factor; Pol30p\tK04802 PCNA; proliferating cell nuclear antigen"
					},
					{
						"name":"CGB_B9610W exonuclease\tK10746 EXO1; exonuclease 1 [EC:3.1.-.-]"
					},
					{
						"name":"CGB_H3700W DNA ligase\tK10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]"
					},
					{
						"name":"CGB_H5160C hypothetical protein\tK24755 WDR76; WD repeat-containing protein 76"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"DSBR (double strand breaks repair)",
			"children":[
			{
				"name":"HR (homologous recombination)",
				"children":[
				{
					"name":"MRN(MRX) complex",
					"children":[
					{
						"name":"CGB_E0670W meiotic DNA double-strand break processing-related protein\tK10865 MRE11; double-strand break repair protein MRE11"
					},
					{
						"name":"CGB_N1500W DNA repair protein Rad50\tK10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]"
					}
					]
				},
				{
					"name":"BRCA1-core complex"
				},
				{
					"name":"BRCA1-A complex"
				},
				{
					"name":"BRCA1-B complex"
				},
				{
					"name":"BRCA1-C complex",
					"children":[
					{
						"name":"CGB_E0670W meiotic DNA double-strand break processing-related protein\tK10865 MRE11; double-strand break repair protein MRE11"
					},
					{
						"name":"CGB_N1500W DNA repair protein Rad50\tK10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]"
					}
					]
				},
				{
					"name":"BRCA complex",
					"children":[
					{
						"name":"CGB_G2270W hypothetical protein\tK08775 BRCA2; breast cancer 2 susceptibility protein"
					},
					{
						"name":"CGB_A8080W recombinase\tK04482 RAD51; DNA repair protein RAD51"
					},
					{
						"name":"CGB_C7740W hypothetical protein\tK04482 RAD51; DNA repair protein RAD51"
					}
					]
				},
				{
					"name":"RecA family proteins",
					"children":[
					{
						"name":"CGB_A8080W recombinase\tK04482 RAD51; DNA repair protein RAD51"
					},
					{
						"name":"CGB_C7740W hypothetical protein\tK04482 RAD51; DNA repair protein RAD51"
					},
					{
						"name":"CGB_A3450C DNA repair protein Rad51\tK10870 RAD51L2; RAD51-like protein 2"
					},
					{
						"name":"CGB_K1500C RAD57 protein\tK10958 RAD57; DNA repair protein RAD57"
					}
					]
				},
				{
					"name":"Rad52 family proteins",
					"children":[
					{
						"name":"CGB_B8180C DNA strand annealing protein\tK10873 RAD52; DNA repair and recombination protein RAD52"
					}
					]
				},
				{
					"name":"Rad54 family proteins",
					"children":[
					{
						"name":"CGB_D5430C DNA recombination and repair protein Rad54B\tK10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]"
					},
					{
						"name":"CGB_C6020W DNA repair protein\tK10877 RAD54B; DNA repair and recombination protein RAD54B [EC:5.6.2.-]"
					}
					]
				},
				{
					"name":"RecQ family DNA helicases",
					"children":[
					{
						"name":"CGB_J2440C ATP-dependent DNA helicase\tK10899 RECQL; ATP-dependent DNA helicase Q1 [EC:5.6.2.4]"
					},
					{
						"name":"CGB_B6150W ATP dependent DNA helicase\tK10901 BLM; bloom syndrome protein [EC:5.6.2.4]"
					},
					{
						"name":"CGB_C6500C ATP-dependent DNA helicase hus2\/rqh1\tK10901 BLM; bloom syndrome protein [EC:5.6.2.4]"
					}
					]
				},
				{
					"name":"Bloom's syndrome complex (BTR)",
					"children":[
					{
						"name":"CGB_B6150W ATP dependent DNA helicase\tK10901 BLM; bloom syndrome protein [EC:5.6.2.4]"
					},
					{
						"name":"CGB_C6500C ATP-dependent DNA helicase hus2\/rqh1\tK10901 BLM; bloom syndrome protein [EC:5.6.2.4]"
					},
					{
						"name":"CGB_D9400W DNA topoisomerase type I\tK03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]"
					},
					{
						"name":"CGB_G3340C hypothetical protein\tK10990 RMI1; RecQ-mediated genome instability protein 1"
					}
					]
				},
				{
					"name":"RPA (replication factor A)",
					"children":[
					{
						"name":"CGB_D5240W damaged DNA binding protein\tK07466 RFA1; replication factor A1"
					},
					{
						"name":"CGB_D7370C hypothetical protein\tK10739 RFA2; replication factor A2"
					},
					{
						"name":"CGB_A3320C single-stranded DNA binding protein 12k chain\tK10740 RPA3; replication factor A3"
					}
					]
				},
				{
					"name":"Protein phosphatase 4",
					"children":[
					{
						"name":"CGB_A4040C hypothetical protein\tK15423 PPP4C; serine\/threonine-protein phosphatase 4 catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"CGB_C7540W protein serine\/threonine phosphatase 4 regulatory subunit 1\tK15424 PPP4R1; serine\/threonine-protein phosphatase 4 regulatory subunit 1"
					},
					{
						"name":"CGB_J1260C nucleus protein\tK17491 SMEK; protein phosphatase 4 regulatory subunit 3"
					}
					]
				},
				{
					"name":"AP-5 complex"
				},
				{
					"name":"SMC5-SMC6 complex",
					"children":[
					{
						"name":"CGB_I0100W nucleus protein\tK22803 SMC5; structural maintenance of chromosomes protein 5"
					},
					{
						"name":"CGB_D6670C DNA repair-related protein\tK22804 SMC6; structural maintenance of chromosomes protein 6"
					},
					{
						"name":"CGB_H0320C DNA repair-related protein\tK22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27]"
					},
					{
						"name":"CGB_D5230C hypothetical protein\tK22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]"
					},
					{
						"name":"CGB_E0660C nucleus protein\tK22825 NSMCE4; non-structural maintenance of chromosomes element 4"
					}
					]
				},
				{
					"name":"Other HR factors",
					"children":[
					{
						"name":"CGB_K3270C hypothetical protein\tK10882 EME1; crossover junction endonuclease EME1 [EC:3.1.22.-]"
					},
					{
						"name":"CGB_A2010C endonuclease\tK08991 MUS81; crossover junction endonuclease MUS81 [EC:3.1.22.-]"
					},
					{
						"name":"CGB_N2050C hypothetical protein\tK10881 SHFM1; 26 proteasome complex subunit DSS1"
					},
					{
						"name":"CGB_E0150C hypothetical protein\tK10991 SWI5; DNA repair protein Swi5\/Sae3"
					},
					{
						"name":"CGB_A3570C GIY-YIG type nuclease catalytic domain containing protein\tK15078 SLX1; structure-specific endonuclease subunit SLX1 [EC:3.6.1.-]"
					},
					{
						"name":"CGB_B6350W hypothetical protein\tK15338 GEN1; holliday junction resolvase GEN1\/YEN1 [EC:3.1.-.-]"
					},
					{
						"name":"CGB_F4100C hypothetical protein\tK11339 MORF4L1; mortality factor 4-like protein 1"
					},
					{
						"name":"CGB_C3320W hypothetical protein\tK22685 WSS1; DNA-dependent metalloprotease WSS1 [EC:3.4.24.-]"
					},
					{
						"name":"CGB_M2260C member of the DEAH family of helicases; Mph1p\tK14635 MPH1; ATP-dependent DNA helicase MPH1 [EC:5.6.2.4]"
					}
					]
				}
				]
			},
			{
				"name":"NHEJ (non-homologous end-joining)",
				"children":[
				{
					"name":"DNA-PK complex",
					"children":[
					{
						"name":"CGB_H4420W hypothetical protein\tK10884 XRCC6; ATP-dependent DNA helicase 2 subunit 1"
					},
					{
						"name":"CGB_B6310W damaged DNA binding protein\tK10885 XRCC5; ATP-dependent DNA helicase 2 subunit 2"
					}
					]
				},
				{
					"name":"MRX complex",
					"children":[
					{
						"name":"CGB_E0670W meiotic DNA double-strand break processing-related protein\tK10865 MRE11; double-strand break repair protein MRE11"
					},
					{
						"name":"CGB_N1500W DNA repair protein Rad50\tK10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]"
					}
					]
				},
				{
					"name":"DNA Ligase 4 complex",
					"children":[
					{
						"name":"CGB_E3020C hypothetical protein\tK10777 LIG4; DNA ligase 4 [EC:6.5.1.1]"
					},
					{
						"name":"CGB_K3320W DNA ligase (ATP)\tK10777 LIG4; DNA ligase 4 [EC:6.5.1.1]"
					}
					]
				},
				{
					"name":"X-family DNA polymerases",
					"children":[
					{
						"name":"CGB_H2300W hypothetical protein\tK03512 POLL; DNA polymerase lambda [EC:2.7.7.7 4.2.99.-]"
					},
					{
						"name":"CGB_D2020C beta DNA polymerase\tK03513 POLM; DNA polymerase mu [EC:2.7.7.7]"
					}
					]
				},
				{
					"name":"Other NHEJ factors",
					"children":[
					{
						"name":"CGB_C7100C hypothetical protein\tK10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]"
					},
					{
						"name":"CGB_K3070W hypothetical protein\tK10887 DCLRE1C; DNA cross-link repair 1C protein [EC:3.1.-.-]"
					}
					]
				}
				]
			},
			{
				"name":"FA (Fanconi anemia) pathway",
				"children":[
				{
					"name":"FA core complex"
				},
				{
					"name":"FA core complex binding factors"
				},
				{
					"name":"Bloom's syndrome complex (BTR)",
					"children":[
					{
						"name":"CGB_B6150W ATP dependent DNA helicase\tK10901 BLM; bloom syndrome protein [EC:5.6.2.4]"
					},
					{
						"name":"CGB_C6500C ATP-dependent DNA helicase hus2\/rqh1\tK10901 BLM; bloom syndrome protein [EC:5.6.2.4]"
					},
					{
						"name":"CGB_D9400W DNA topoisomerase type I\tK03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]"
					},
					{
						"name":"CGB_G3340C hypothetical protein\tK10990 RMI1; RecQ-mediated genome instability protein 1"
					}
					]
				},
				{
					"name":"FANCD2-I complex"
				},
				{
					"name":"Downstream FA components",
					"children":[
					{
						"name":"CGB_G2270W hypothetical protein\tK08775 BRCA2; breast cancer 2 susceptibility protein"
					}
					]
				},
				{
					"name":"Other FA pathway factors",
					"children":[
					{
						"name":"CGB_M3340W hypothetical protein\tK15363 FAN1; fanconi-associated nuclease 1 [EC:3.1.21.- 3.1.4.1]"
					},
					{
						"name":"CGB_A8080W recombinase\tK04482 RAD51; DNA repair protein RAD51"
					},
					{
						"name":"CGB_C7740W hypothetical protein\tK04482 RAD51; DNA repair protein RAD51"
					},
					{
						"name":"CGB_A3450C DNA repair protein Rad51\tK10870 RAD51L2; RAD51-like protein 2"
					},
					{
						"name":"CGB_H3330W telomeric DNA binding protein\tK11137 TELO2; telomere length regulation protein"
					},
					{
						"name":"CGB_N0150C hypothetical protein\tK15361 WDR48; WD repeat-containing protein 48"
					}
					]
				}
				]
			},
			{
				"name":"Other DSBR factors",
				"children":[
				{
					"name":"Protein phosphatase 6",
					"children":[
					{
						"name":"CGB_I1360C serine\/threonine protein phosphatase 6, (PP6) (Protein phosphatase V) (PP-V)\tK15498 PPP6C; serine\/threonine-protein phosphatase 6 catalytic subunit [EC:3.1.3.16]"
					}
					]
				},
				{
					"name":"Ubiquitin ligases"
				},
				{
					"name":"Others",
					"children":[
					{
						"name":"CGB_J1610W guanyl nucleotide binding protein\tK23314 WRAP53; telomerase Cajal body protein 1"
					},
					{
						"name":"CGB_J2040W transcription factor\tK24752 WDR70; WD repeat-containing protein 70"
					},
					{
						"name":"CGB_H5160C hypothetical protein\tK24755 WDR76; WD repeat-containing protein 76"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"TLS (translesion DNA synthesis) factors",
			"children":[
			{
				"name":"Y-family DNA polymerases",
				"children":[
				{
					"name":"CGB_E4710W eta DNA polymerase\tK03509 POLH; DNA polymerase eta [EC:2.7.7.7]"
				},
				{
					"name":"CGB_D2570C hypothetical protein\tK03511 POLK; DNA polymerase kappa [EC:2.7.7.7]"
				},
				{
					"name":"CGB_B2050C hypothetical protein\tK03515 REV1; DNA repair protein REV1 [EC:2.7.7.-]"
				}
				]
			},
			{
				"name":"B-family DNA polymerases",
				"children":[
				{
					"name":"CGB_A2410C zeta DNA polymerase\tK02350 REV3L; DNA polymerase zeta [EC:2.7.7.7]"
				}
				]
			},
			{
				"name":"A-family DNA polymerase"
			},
			{
				"name":"Rad6 epistasis group",
				"children":[
				{
					"name":"CGB_A9410W ubiquitin-conjugating enzyme E2-17 kDa\tK10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]"
				},
				{
					"name":"CGB_L2250C hypothetical protein\tK10627 RAD18; E3 ubiquitin-protein ligase RAD18 [EC:2.3.2.27]"
				},
				{
					"name":"CGB_B3320W DNA repair protein RAD16; Rad16p\tK15505 RAD5; DNA repair protein RAD5 [EC:5.6.2.-]"
				},
				{
					"name":"CGB_D1820C SWI\/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 3\tK15711 SMARCA3; SWI\/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A3 [EC:5.6.2. 2.3.2.27]"
				},
				{
					"name":"CGB_I2280C DNA repair protein RAD5\tK15711 SMARCA3; SWI\/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A3 [EC:5.6.2. 2.3.2.27]"
				},
				{
					"name":"CGB_F5420C hypothetical protein\tK10704 UBE2V; ubiquitin-conjugating enzyme E2 variant"
				},
				{
					"name":"CGB_E5170C hypothetical protein\tK10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]"
				}
				]
			},
			{
				"name":"Other TLS factors",
				"children":[
				{
					"name":"CGB_M1090C DNA processivity factor; Pol30p\tK04802 PCNA; proliferating cell nuclear antigen"
				},
				{
					"name":"CGB_G6140W hypothetical protein\tK26957 GCNA; germ cell nuclear acidic protein"
				}
				]
			}
			]
		},
		{
			"name":"Check point factors",
			"children":[
			{
				"name":"Rad9-Hus1-Rad1 complex",
				"children":[
				{
					"name":"CGB_E1050W hypothetical protein\tK10994 RAD9A; cell cycle checkpoint control protein RAD9A [EC:3.1.11.2]"
				},
				{
					"name":"CGB_I4290C hypothetical protein\tK10903 HUS1; HUS1 checkpoint protein"
				},
				{
					"name":"CGB_A0400W DNA repair protein Rad1\tK02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]"
				}
				]
			},
			{
				"name":"HRAD17(Rad24)-RFC complex",
				"children":[
				{
					"name":"CGB_A1780W RAD17 isoform 4\tK06662 HRAD17; cell cycle checkpoint protein"
				},
				{
					"name":"CGB_G3360C subunit of heteropentameric Replication factor C (RF-C); Rfc3p\tK10755 RFC2_4; replication factor C subunit 2\/4"
				},
				{
					"name":"CGB_L0470C DNA replication factor (activator 1 subunit)\tK10755 RFC2_4; replication factor C subunit 2\/4"
				},
				{
					"name":"CGB_A1550C subunit of DNA Replication factor C (RF-C); Rfc5p\tK10756 RFC3_5; replication factor C subunit 3\/5"
				},
				{
					"name":"CGB_N0500W DNA replication factor\tK10756 RFC3_5; replication factor C subunit 3\/5"
				}
				]
			},
			{
				"name":"Rad17-Mec3-Ddc1 complex",
				"children":[
				{
					"name":"CGB_A0400W DNA repair protein Rad1\tK02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]"
				}
				]
			},
			{
				"name":"FPC (fork protection complex)",
				"children":[
				{
					"name":"CGB_F6260W hypothetical protein\tK10997 TIMELESS; replication fork protection complex subunit TIMELESS\/Tof1\/Swi1"
				},
				{
					"name":"CGB_D9370W hypothetical protein\tK10998 TIPIN; replication fork protection complex subunit TIPIN\/Csm3\/Swi3"
				},
				{
					"name":"CGB_C9130W hypothetical protein\tK11272 MRC1; mediator of replication checkpoint protein 1"
				}
				]
			},
			{
				"name":"Triple T complex",
				"children":[
				{
					"name":"CGB_H3330W telomeric DNA binding protein\tK11137 TELO2; telomere length regulation protein"
				},
				{
					"name":"CGB_B8020C hypothetical protein\tK20403 TTI1; TELO2-interacting protein 1"
				}
				]
			},
			{
				"name":"BAG6-UBL4A-GET4 complex",
				"children":[
				{
					"name":"CGB_L2580C hypothetical protein\tK23388 UBL4; ubiquitin-like protein 4"
				},
				{
					"name":"CGB_A7310W cytoplasm protein\tK23387 GET4; golgi to ER traffic protein 4"
				}
				]
			},
			{
				"name":"SOSS complex"
			},
			{
				"name":"Other check point factors",
				"children":[
				{
					"name":"CGB_E4070C DNA-repair protein rad3\tK06640 ATR; serine\/threonine-protein kinase ATR [EC:2.7.11.1]"
				},
				{
					"name":"CGB_F3720C telomere length control protein\tK04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]"
				},
				{
					"name":"CGB_G1060W hypothetical protein\tK02216 CHEK1; serine\/threonine-protein kinase CHEK1 [EC:2.7.11.1]"
				},
				{
					"name":"CGB_C1390W mih1p\tK02555 MIH1; M-phase inducer tyrosine phosphatase [EC:3.1.3.48]"
				},
				{
					"name":"CGB_J1220W 14-3-3 protein\tK06630 YWHAE; 14-3-3 protein epsilon"
				},
				{
					"name":"CGB_J1410C protein threonine\/tyrosine kinase\tK02831 RAD53; ser\/thr\/tyr protein kinase RAD53 [EC:2.7.11.-]"
				},
				{
					"name":"CGB_G1100C MYT1 kinase\tK03114 SWE1; mitosis inhibitor protein kinase SWE1 [EC:2.7.11.1]"
				},
				{
					"name":"CGB_G3640W hypothetical protein\tK03114 SWE1; mitosis inhibitor protein kinase SWE1 [EC:2.7.11.1]"
				},
				{
					"name":"CGB_H1070W ATPase\tK12196 VPS4; vacuolar protein-sorting-associated protein 4"
				},
				{
					"name":"CGB_F1170C hypothetical protein\tK25059 SDE2; replication stress response regulator SDE2"
				}
				]
			}
			]
		},
		{
			"name":"Other factors with a suspected DNA repair function",
			"children":[
			{
				"name":"DNA polymerases",
				"children":[
				{
					"name":"CGB_C2360W DNA-directed DNA polymerase\tK02331 POL5; DNA polymerase phi [EC:2.7.7.7]"
				}
				]
			},
			{
				"name":"Nucleases",
				"children":[
				{
					"name":"CGB_G0680W hypothetical protein\tK15340 DCLRE1A; DNA cross-link repair 1A protein"
				},
				{
					"name":"CGB_M1270C hypothetical protein\tK17815 EXO5; exonuclease V [EC:3.1.-.-]"
				},
				{
					"name":"CGB_B2870W hypothetical protein\tK05986 NUCS; nuclease S1 [EC:3.1.30.1]"
				}
				]
			},
			{
				"name":"Helicases",
				"children":[
				{
					"name":"CGB_N2390C helicase domain DNA excision repair protein (Rad26L)\tK20098 ERCC6L2; DNA excision repair protein ERCC-6-like 2 [EC:5.6.2.-]"
				}
				]
			},
			{
				"name":"PSO4 complex",
				"children":[
				{
					"name":"CGB_C3450C nuclear matrix protein NMP200\tK10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]"
				},
				{
					"name":"CGB_K2410C pre-mRNA splicing factor CEF1 (PRP19-associated complex protein 85)\tK12860 CDC5L; pre-mRNA-splicing factor CDC5\/CEF1"
				},
				{
					"name":"CGB_F2480C hypothetical protein\tK12861 BCAS2; pre-mRNA-splicing factor SPF27"
				},
				{
					"name":"CGB_G2330C nuclear mRNA splicing, via spliceosome-related protein\tK12862 PLRG1; pleiotropic regulator 1"
				}
				]
			},
			{
				"name":"Modulation of nucleotide pools",
				"children":[
				{
					"name":"CGB_I3680C hypothetical protein\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]"
				},
				{
					"name":"CGB_I4405C dUTPase; Dut1p\tK01520 dut; dUTP diphosphatase [EC:3.6.1.23]"
				},
				{
					"name":"CGB_M2010W dUTP diphosphatase\tK01520 dut; dUTP diphosphatase [EC:3.6.1.23]"
				},
				{
					"name":"CGB_E4330W ribonucleoside-diphosphate reductase large chain\tK10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]"
				},
				{
					"name":"CGB_K1260W ribonucleoside-diphosphate reductase\tK10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]"
				},
				{
					"name":"CGB_K2480W ribonucleotide reductase small subunit\tK10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic type",
		"children":[
		{
			"name":"SSBR (single strand breaks repair)",
			"children":[
			{
				"name":"Direct repair"
			},
			{
				"name":"BER (base exicision repair)",
				"children":[
				{
					"name":"DNA glycosylases",
					"children":[
					{
						"name":"CGB_A7690W uracil DNA N-glycosylase\tK03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]"
					},
					{
						"name":"CGB_D2530C DNA-3-methyladenine glycosidase\tK01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]"
					},
					{
						"name":"CGB_B0690W A\/G-specific adenine DNA glycosylase\tK03575 mutY; A\/G-specific adenine glycosylase [EC:3.2.2.31]"
					},
					{
						"name":"CGB_L0290C hypothetical protein\tK10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]"
					},
					{
						"name":"CGB_G1430W DNA-(apurinic or apyrimidinic site) lyase\tK10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]"
					}
					]
				},
				{
					"name":"AP endonucleases"
				},
				{
					"name":"RecJ"
				},
				{
					"name":"DNA ligase"
				},
				{
					"name":"DNA polymerase I"
				}
				]
			},
			{
				"name":"NER (nucleotide excision repair)",
				"children":[
				{
					"name":"GGR (global genome repair) factors",
					"children":[
					{
						"name":"CGB_C0700C ATP-dependent DNA helicase\tK03657 uvrD; ATP-dependent DNA helicase UvrD\/PcrA [EC:5.6.2.4]"
					}
					]
				},
				{
					"name":"TCR (transcription coupled repair) factors",
					"children":[
					{
						"name":"DNA-directed RNA polymerase complex (RNAP)"
					},
					{
						"name":"TRCF (transcription-repair coupling factor)"
					}
					]
				}
				]
			},
			{
				"name":"MMR (mismatch excision repair)",
				"children":[
				{
					"name":"Mismatch and loop recognition factors"
				},
				{
					"name":"Molecular matchmaker"
				},
				{
					"name":"Strand discrimination factor"
				},
				{
					"name":"DNA exonucleases"
				},
				{
					"name":"DNA polymerase III holoenzyme"
				},
				{
					"name":"DNA ligase"
				},
				{
					"name":"Other MMR factors",
					"children":[
					{
						"name":"CGB_C0700C ATP-dependent DNA helicase\tK03657 uvrD; ATP-dependent DNA helicase UvrD\/PcrA [EC:5.6.2.4]"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"DSBR (double strand breaks repair)",
			"children":[
			{
				"name":"HR (homologous recombination)",
				"children":[
				{
					"name":"RecBC pathway proteins"
				},
				{
					"name":"RecFOR pathway proteins"
				},
				{
					"name":"AddAB pathway proteins"
				},
				{
					"name":"Other HR factor"
				},
				{
					"name":"Archaeal homologous recombinant proteins"
				}
				]
			},
			{
				"name":"NHEJ (non-homologous end-joining)",
				"children":[
				{
					"name":"Two-component NHEJ DNA repair complex"
				},
				{
					"name":"SHIIR (short-homology-independent illegitimate recombination)",
					"children":[
					{
						"name":"Facilitator"
					},
					{
						"name":"Supressor"
					}
					]
				},
				{
					"name":"SHDIR (short-homology-dependent illegitimate recombination)",
					"children":[
					{
						"name":"RecET pathway"
					},
					{
						"name":"Facilitator"
					},
					{
						"name":"Supressor"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"TLS (translesion DNA synthesis) factors",
			"children":[
			{
				"name":"Y-family DNA polymerases"
			},
			{
				"name":"Other SOS response factors"
			}
			]
		},
		{
			"name":"Other factors with a suspected DNA repair function",
			"children":[
			{
				"name":"DNA polymerase"
			},
			{
				"name":"DNA helicases"
			},
			{
				"name":"Modulation of nucleotide pools",
				"children":[
				{
					"name":"CGB_I3680C hypothetical protein\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]"
				},
				{
					"name":"CGB_I4405C dUTPase; Dut1p\tK01520 dut; dUTP diphosphatase [EC:3.6.1.23]"
				},
				{
					"name":"CGB_M2010W dUTP diphosphatase\tK01520 dut; dUTP diphosphatase [EC:3.6.1.23]"
				}
				]
			},
			{
				"name":"Others"
			}
			]
		}
		]
	}
	]
}