{
	"name":"cir03400",
	"children":[
	{
		"name":"Eukaryotic type",
		"children":[
		{
			"name":"SSBR (single strand breaks repair)",
			"children":[
			{
				"name":"Direct repair",
				"children":[
				{
					"name":"C2U53_22825 methylated-DNA--[protein]-cysteine S-methyltransferase\tK00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]"
				},
				{
					"name":"C2U53_17040 deoxyribodipyrimidine photo-lyase\tK01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]"
				}
				]
			},
			{
				"name":"BER (base exicision repair)",
				"children":[
				{
					"name":"DNA glycosylases",
					"children":[
					{
						"name":"C2U53_29235 uracil-DNA glycosylase\tK03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]"
					},
					{
						"name":"C2U53_05195 adenine DNA glycosylase\tK03575 mutY; A\/G-specific adenine glycosylase [EC:3.2.2.31]"
					},
					{
						"name":"C2U53_21650 endonuclease III\tK10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]"
					}
					]
				},
				{
					"name":"AP endonucleases"
				},
				{
					"name":"Long Patch-BER factors",
					"children":[
					{
						"name":"DNA polymerase delta complex"
					},
					{
						"name":"DNA polymerase epsilon complex"
					}
					]
				},
				{
					"name":"Short Patch-BER factors"
				},
				{
					"name":"Other BER factors"
				}
				]
			},
			{
				"name":"NER (nucleotide excision repair)",
				"children":[
				{
					"name":"GGR (global genome repair) factors",
					"children":[
					{
						"name":"XPC-HR23B-CETN2 complex"
					},
					{
						"name":"Cul4-DDB2 complex"
					},
					{
						"name":"NER4 complex"
					}
					]
				},
				{
					"name":"TCR (transcription coupled repair) factors",
					"children":[
					{
						"name":"DNA-directed RNA polymerase II complex"
					},
					{
						"name":"Cul4-CSA complex"
					},
					{
						"name":"Other TCR factor"
					}
					]
				},
				{
					"name":"TFIIH complex"
				},
				{
					"name":"RPA (replication factor A)"
				},
				{
					"name":"Other NER factors"
				}
				]
			},
			{
				"name":"MMR (mismatch excision repair)",
				"children":[
				{
					"name":"Mismatch and loop recognition factors"
				},
				{
					"name":"MutL homologs"
				},
				{
					"name":"DNA polymerase delta complex"
				},
				{
					"name":"RPA (replication factor A)"
				},
				{
					"name":"RFC (replication factor C)"
				},
				{
					"name":"Other MMR factors"
				}
				]
			}
			]
		},
		{
			"name":"DSBR (double strand breaks repair)",
			"children":[
			{
				"name":"HR (homologous recombination)",
				"children":[
				{
					"name":"MRN(MRX) complex"
				},
				{
					"name":"BRCA1-core complex"
				},
				{
					"name":"BRCA1-A complex"
				},
				{
					"name":"BRCA1-B complex"
				},
				{
					"name":"BRCA1-C complex"
				},
				{
					"name":"BRCA complex"
				},
				{
					"name":"RecA family proteins"
				},
				{
					"name":"Rad52 family proteins"
				},
				{
					"name":"Rad54 family proteins"
				},
				{
					"name":"RecQ family DNA helicases"
				},
				{
					"name":"Bloom's syndrome complex (BTR)"
				},
				{
					"name":"RPA (replication factor A)"
				},
				{
					"name":"Protein phosphatase 4"
				},
				{
					"name":"AP-5 complex"
				},
				{
					"name":"SMC5-SMC6 complex"
				},
				{
					"name":"Other HR factors"
				}
				]
			},
			{
				"name":"NHEJ (non-homologous end-joining)",
				"children":[
				{
					"name":"DNA-PK complex"
				},
				{
					"name":"MRX complex"
				},
				{
					"name":"DNA Ligase 4 complex"
				},
				{
					"name":"X-family DNA polymerases"
				},
				{
					"name":"Other NHEJ factors"
				}
				]
			},
			{
				"name":"FA (Fanconi anemia) pathway",
				"children":[
				{
					"name":"FA core complex"
				},
				{
					"name":"FA core complex binding factors"
				},
				{
					"name":"Bloom's syndrome complex (BTR)"
				},
				{
					"name":"FANCD2-I complex"
				},
				{
					"name":"Downstream FA components"
				},
				{
					"name":"Other FA pathway factors"
				}
				]
			},
			{
				"name":"Other DSBR factors",
				"children":[
				{
					"name":"Protein phosphatase 6"
				},
				{
					"name":"Ubiquitin ligases"
				},
				{
					"name":"Others"
				}
				]
			}
			]
		},
		{
			"name":"TLS (translesion DNA synthesis) factors",
			"children":[
			{
				"name":"Y-family DNA polymerases"
			},
			{
				"name":"B-family DNA polymerases"
			},
			{
				"name":"A-family DNA polymerase"
			},
			{
				"name":"Rad6 epistasis group"
			},
			{
				"name":"Other TLS factors"
			}
			]
		},
		{
			"name":"Check point factors",
			"children":[
			{
				"name":"Rad9-Hus1-Rad1 complex"
			},
			{
				"name":"HRAD17(Rad24)-RFC complex"
			},
			{
				"name":"Rad17-Mec3-Ddc1 complex"
			},
			{
				"name":"FPC (fork protection complex)"
			},
			{
				"name":"Triple T complex"
			},
			{
				"name":"BAG6-UBL4A-GET4 complex"
			},
			{
				"name":"SOSS complex"
			},
			{
				"name":"Other check point factors"
			}
			]
		},
		{
			"name":"Other factors with a suspected DNA repair function",
			"children":[
			{
				"name":"DNA polymerases"
			},
			{
				"name":"Nucleases"
			},
			{
				"name":"Helicases"
			},
			{
				"name":"PSO4 complex"
			},
			{
				"name":"Modulation of nucleotide pools",
				"children":[
				{
					"name":"C2U53_04385 8-oxo-dGTP diphosphatase MutT\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]"
				},
				{
					"name":"C2U53_09055 dUTP diphosphatase\tK01520 dut; dUTP diphosphatase [EC:3.6.1.23]"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic type",
		"children":[
		{
			"name":"SSBR (single strand breaks repair)",
			"children":[
			{
				"name":"Direct repair",
				"children":[
				{
					"name":"C2U53_22825 methylated-DNA--[protein]-cysteine S-methyltransferase\tK00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]"
				},
				{
					"name":"C2U53_27065 bifunctional DNA-binding transcriptional regulator\/O6-methylguanine-DNA methyltransferase Ada\tK10778 ada; AraC family transcriptional regulator, regulatory protein of adaptative response \/ methylated-DNA-[protein]-cysteine methyltransferase [EC:2.1.1.63]"
				},
				{
					"name":"C2U53_17040 deoxyribodipyrimidine photo-lyase\tK01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]"
				},
				{
					"name":"C2U53_27060 DNA oxidative demethylase AlkB\tK03919 alkB; DNA oxidative demethylase [EC:1.14.11.33]"
				}
				]
			},
			{
				"name":"BER (base exicision repair)",
				"children":[
				{
					"name":"DNA glycosylases",
					"children":[
					{
						"name":"C2U53_29235 uracil-DNA glycosylase\tK03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]"
					},
					{
						"name":"C2U53_06015 G\/U mismatch-specific DNA glycosylase\tK03649 mug; double-stranded uracil-DNA glycosylase [EC:3.2.2.28]"
					},
					{
						"name":"C2U53_26380 DNA-3-methyladenine glycosylase 2\tK01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]"
					},
					{
						"name":"C2U53_05195 adenine DNA glycosylase\tK03575 mutY; A\/G-specific adenine glycosylase [EC:3.2.2.31]"
					},
					{
						"name":"C2U53_08630 DNA-3-methyladenine glycosylase I\tK01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]"
					},
					{
						"name":"C2U53_09030 bifunctional DNA-formamidopyrimidine glycosylase\/DNA-(apurinic or apyrimidinic site) lyase\tK10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]"
					},
					{
						"name":"C2U53_17080 endonuclease VIII\tK05522 nei; endonuclease VIII [EC:3.2.2.- 4.2.99.18]"
					},
					{
						"name":"C2U53_21650 endonuclease III\tK10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]"
					}
					]
				},
				{
					"name":"AP endonucleases",
					"children":[
					{
						"name":"C2U53_20980 exodeoxyribonuclease III\tK01142 xthA; exodeoxyribonuclease III [EC:3.1.11.2]"
					},
					{
						"name":"C2U53_26775 deoxyribonuclease IV\tK01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]"
					},
					{
						"name":"C2U53_11360 deoxyribonuclease V\tK05982 nfi; deoxyribonuclease V [EC:3.1.21.7]"
					}
					]
				},
				{
					"name":"RecJ",
					"children":[
					{
						"name":"C2U53_14005 single-stranded-DNA-specific exonuclease RecJ\tK07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]"
					}
					]
				},
				{
					"name":"DNA ligase",
					"children":[
					{
						"name":"C2U53_09215 NAD-dependent DNA ligase LigB\tK01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]"
					},
					{
						"name":"C2U53_28410 ligA; NAD-dependent DNA ligase LigA\tK01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]"
					}
					]
				},
				{
					"name":"DNA polymerase I",
					"children":[
					{
						"name":"C2U53_10490 DNA polymerase I\tK02335 polA; DNA polymerase I [EC:2.7.7.7]"
					}
					]
				}
				]
			},
			{
				"name":"NER (nucleotide excision repair)",
				"children":[
				{
					"name":"GGR (global genome repair) factors",
					"children":[
					{
						"name":"C2U53_11850 excinuclease ABC subunit UvrA\tK03701 uvrA; excinuclease ABC subunit A"
					},
					{
						"name":"C2U53_17535 excinuclease ABC subunit B\tK03702 uvrB; excinuclease ABC subunit B"
					},
					{
						"name":"C2U53_25020 uvrC; excinuclease ABC subunit C\tK03703 uvrC; excinuclease ABC subunit C"
					},
					{
						"name":"C2U53_21020 excinuclease Cho\tK05984 cho; excinuclease Cho [EC:3.1.25.-]"
					},
					{
						"name":"C2U53_05975 RNA helicase\tK03657 uvrD; ATP-dependent DNA helicase UvrD\/PcrA [EC:5.6.2.4]"
					},
					{
						"name":"C2U53_10275 DNA helicase II\tK03657 uvrD; ATP-dependent DNA helicase UvrD\/PcrA [EC:5.6.2.4]"
					},
					{
						"name":"C2U53_10490 DNA polymerase I\tK02335 polA; DNA polymerase I [EC:2.7.7.7]"
					},
					{
						"name":"C2U53_09215 NAD-dependent DNA ligase LigB\tK01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]"
					},
					{
						"name":"C2U53_28410 ligA; NAD-dependent DNA ligase LigA\tK01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]"
					}
					]
				},
				{
					"name":"TCR (transcription coupled repair) factors",
					"children":[
					{
						"name":"DNA-directed RNA polymerase complex (RNAP)",
						"children":[
						{
							"name":"C2U53_11290 rpoB; DNA-directed RNA polymerase subunit beta\tK03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]"
						},
						{
							"name":"C2U53_11295 rpoC; DNA-directed RNA polymerase subunit beta'\tK03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]"
						},
						{
							"name":"C2U53_07185 DNA-directed RNA polymerase subunit alpha\tK03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]"
						},
						{
							"name":"C2U53_09225 DNA-directed RNA polymerase subunit omega\tK03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]"
						}
						]
					},
					{
						"name":"TRCF (transcription-repair coupling factor)",
						"children":[
						{
							"name":"C2U53_20605 transcription-repair coupling factor\tK03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]"
						}
						]
					}
					]
				}
				]
			},
			{
				"name":"MMR (mismatch excision repair)",
				"children":[
				{
					"name":"Mismatch and loop recognition factors",
					"children":[
					{
						"name":"C2U53_03530 mutS; DNA mismatch repair protein MutS\tK03555 mutS; DNA mismatch repair protein MutS"
					}
					]
				},
				{
					"name":"Molecular matchmaker",
					"children":[
					{
						"name":"C2U53_12650 DNA mismatch repair endonuclease MutL\tK03572 mutL; DNA mismatch repair protein MutL"
					}
					]
				},
				{
					"name":"Strand discrimination factor",
					"children":[
					{
						"name":"C2U53_14605 DNA mismatch repair endonuclease MutH\tK03573 mutH; DNA mismatch repair protein MutH"
					}
					]
				},
				{
					"name":"DNA exonucleases",
					"children":[
					{
						"name":"C2U53_26120 exodeoxyribonuclease I\tK01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]"
					},
					{
						"name":"C2U53_28845 exodeoxyribonuclease VII large subunit\tK03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]"
					},
					{
						"name":"C2U53_15700 exodeoxyribonuclease VII small subunit\tK03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]"
					},
					{
						"name":"C2U53_24295 exodeoxyribonuclease X\tK10857 exoX; exodeoxyribonuclease X [EC:3.1.11.-]"
					}
					]
				},
				{
					"name":"DNA polymerase III holoenzyme",
					"children":[
					{
						"name":"C2U53_03965 DNA polymerase III subunit alpha\tK02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]"
					},
					{
						"name":"C2U53_01945 DNA polymerase III subunit beta\tK02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]"
					},
					{
						"name":"C2U53_09675 DNA polymerase III subunit beta\tK02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]"
					},
					{
						"name":"C2U53_13180 DNA polymerase III subunit chi\tK02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7]"
					},
					{
						"name":"C2U53_16770 DNA polymerase III subunit delta\tK02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]"
					},
					{
						"name":"C2U53_20520 holB; DNA polymerase III subunit delta'\tK02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]"
					},
					{
						"name":"C2U53_00220 3'-5' exonuclease\tK02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]"
					},
					{
						"name":"C2U53_03795 DNA polymerase III subunit epsilon\tK02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]"
					},
					{
						"name":"C2U53_16000 DNA polymerase III subunit gamma\/tau\tK02343 dnaX; DNA polymerase III subunit gamma\/tau [EC:2.7.7.7]"
					},
					{
						"name":"C2U53_13775 DNA polymerase III subunit psi\tK02344 holD; DNA polymerase III subunit psi [EC:2.7.7.7]"
					},
					{
						"name":"C2U53_01165 DNA polymerase III subunit theta\tK02345 holE; DNA polymerase III subunit theta [EC:2.7.7.7]"
					},
					{
						"name":"C2U53_24285 DNA polymerase III subunit theta\tK02345 holE; DNA polymerase III subunit theta [EC:2.7.7.7]"
					},
					{
						"name":"C2U53_25335 DNA polymerase III subunit theta\tK02345 holE; DNA polymerase III subunit theta [EC:2.7.7.7]"
					}
					]
				},
				{
					"name":"DNA ligase",
					"children":[
					{
						"name":"C2U53_09215 NAD-dependent DNA ligase LigB\tK01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]"
					},
					{
						"name":"C2U53_28410 ligA; NAD-dependent DNA ligase LigA\tK01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]"
					}
					]
				},
				{
					"name":"Other MMR factors",
					"children":[
					{
						"name":"C2U53_05975 RNA helicase\tK03657 uvrD; ATP-dependent DNA helicase UvrD\/PcrA [EC:5.6.2.4]"
					},
					{
						"name":"C2U53_10275 DNA helicase II\tK03657 uvrD; ATP-dependent DNA helicase UvrD\/PcrA [EC:5.6.2.4]"
					},
					{
						"name":"C2U53_00030 single-stranded DNA-binding protein\tK03111 ssb; single-strand DNA-binding protein"
					},
					{
						"name":"C2U53_01155 single-stranded DNA-binding protein\tK03111 ssb; single-strand DNA-binding protein"
					},
					{
						"name":"C2U53_01905 single-stranded DNA-binding protein\tK03111 ssb; single-strand DNA-binding protein"
					},
					{
						"name":"C2U53_11855 single-stranded DNA-binding protein SSB1\tK03111 ssb; single-strand DNA-binding protein"
					},
					{
						"name":"C2U53_01950 DNA adenine methylase\tK06223 dam; DNA adenine methylase [EC:2.1.1.72]"
					},
					{
						"name":"C2U53_07540 adenine-specific DNA-methyltransferase\tK06223 dam; DNA adenine methylase [EC:2.1.1.72]"
					},
					{
						"name":"C2U53_17790 adenine methylase\tK06223 dam; DNA adenine methylase [EC:2.1.1.72]"
					},
					{
						"name":"C2U53_18435 adenine methylase\tK06223 dam; DNA adenine methylase [EC:2.1.1.72]"
					},
					{
						"name":"C2U53_25620 very short patch repair endonuclease\tK07458 vsr; DNA mismatch endonuclease, patch repair protein [EC:3.1.-.-]"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"DSBR (double strand breaks repair)",
			"children":[
			{
				"name":"HR (homologous recombination)",
				"children":[
				{
					"name":"RecBC pathway proteins",
					"children":[
					{
						"name":"C2U53_14665 exodeoxyribonuclease V subunit beta\tK03582 recB; exodeoxyribonuclease V beta subunit [EC:3.1.11.5]"
					},
					{
						"name":"C2U53_14655 exodeoxyribonuclease V subunit gamma\tK03583 recC; exodeoxyribonuclease V gamma subunit [EC:3.1.11.5]"
					},
					{
						"name":"C2U53_14670 exodeoxyribonuclease V subunit alpha\tK03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]"
					},
					{
						"name":"C2U53_03335 recA; recombinase RecA\tK03553 recA; recombination protein RecA"
					},
					{
						"name":"C2U53_24385 Holliday junction branch migration protein RuvA\tK03550 ruvA; holliday junction DNA helicase RuvA"
					},
					{
						"name":"C2U53_24380 Holliday junction branch migration DNA helicase RuvB\tK03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]"
					},
					{
						"name":"C2U53_24390 crossover junction endodeoxyribonuclease RuvC\tK01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]"
					},
					{
						"name":"C2U53_27980 RusA family crossover junction endodeoxyribonuclease\tK01160 rusA; crossover junction endodeoxyribonuclease RusA [EC:3.1.21.10]"
					},
					{
						"name":"C2U53_10975 primosomal protein N'\tK04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]"
					},
					{
						"name":"C2U53_12740 primosomal replication protein N\tK02686 priB; primosomal replication protein N"
					},
					{
						"name":"C2U53_15985 primosomal replication protein N''\tK04067 priC; primosomal replication protein N''"
					},
					{
						"name":"C2U53_13685 primosomal protein DnaT\tK02317 dnaT; DNA replication protein DnaT"
					},
					{
						"name":"C2U53_26120 exodeoxyribonuclease I\tK01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]"
					},
					{
						"name":"C2U53_15510 exonuclease subunit SbcC\tK03546 sbcC; DNA repair protein SbcC\/Rad50"
					},
					{
						"name":"C2U53_15515 exonuclease subunit SbcD\tK03547 sbcD; DNA repair protein SbcD\/Mre11"
					}
					]
				},
				{
					"name":"RecFOR pathway proteins",
					"children":[
					{
						"name":"C2U53_03335 recA; recombinase RecA\tK03553 recA; recombination protein RecA"
					},
					{
						"name":"C2U53_13860 DNA repair protein RadA\tK04485 radA; DNA repair protein RadA\/Sms"
					},
					{
						"name":"C2U53_09670 DNA replication and repair protein RecF\tK03629 recF; DNA replication and repair protein RecF"
					},
					{
						"name":"C2U53_09240 DNA helicase RecG\tK03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]"
					},
					{
						"name":"C2U53_15130 IS66 family insertion sequence hypothetical protein\tK03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]"
					},
					{
						"name":"C2U53_14005 single-stranded-DNA-specific exonuclease RecJ\tK07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]"
					},
					{
						"name":"C2U53_29165 DNA repair protein RecO\tK03584 recO; DNA repair protein RecO (recombination protein O)"
					},
					{
						"name":"C2U53_16010 recombination protein RecR\tK06187 recR; recombination protein RecR"
					},
					{
						"name":"C2U53_29425 DNA repair protein RecN\tK03631 recN; DNA repair protein RecN (Recombination protein N)"
					},
					{
						"name":"C2U53_01960 recombination-associated protein RdgC\tK03554 rdgC; recombination associated protein RdgC"
					},
					{
						"name":"C2U53_15500 recombination-associated protein RdgC\tK03554 rdgC; recombination associated protein RdgC"
					},
					{
						"name":"C2U53_24385 Holliday junction branch migration protein RuvA\tK03550 ruvA; holliday junction DNA helicase RuvA"
					},
					{
						"name":"C2U53_24380 Holliday junction branch migration DNA helicase RuvB\tK03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]"
					},
					{
						"name":"C2U53_24390 crossover junction endodeoxyribonuclease RuvC\tK01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]"
					}
					]
				},
				{
					"name":"AddAB pathway proteins"
				},
				{
					"name":"Other HR factor",
					"children":[
					{
						"name":"C2U53_26915 ATP-dependent helicase\tK19789 radD; DNA repair protein RadD"
					}
					]
				},
				{
					"name":"Archaeal homologous recombinant proteins",
					"children":[
					{
						"name":"C2U53_15510 exonuclease subunit SbcC\tK03546 sbcC; DNA repair protein SbcC\/Rad50"
					},
					{
						"name":"C2U53_15515 exonuclease subunit SbcD\tK03547 sbcD; DNA repair protein SbcD\/Mre11"
					},
					{
						"name":"C2U53_13205 DUF853 domain-containing protein\tK06915 herA; DNA double-strand break repair helicase HerA and related ATPase"
					}
					]
				}
				]
			},
			{
				"name":"NHEJ (non-homologous end-joining)",
				"children":[
				{
					"name":"Two-component NHEJ DNA repair complex"
				},
				{
					"name":"SHIIR (short-homology-independent illegitimate recombination)",
					"children":[
					{
						"name":"Facilitator",
						"children":[
						{
							"name":"C2U53_27150 DNA gyrase subunit A\tK02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]"
						},
						{
							"name":"C2U53_09665 gyrB; DNA topoisomerase (ATP-hydrolyzing) subunit B\tK02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]"
						},
						{
							"name":"C2U53_23125 topA; type I DNA topoisomerase\tK03168 topA; DNA topoisomerase I [EC:5.6.2.1]"
						}
						]
					},
					{
						"name":"Supressor",
						"children":[
						{
							"name":"C2U53_11370 DNA-binding protein HU-alpha\tK05787 hupA; DNA-binding protein HU-alpha"
						},
						{
							"name":"C2U53_15815 DNA-binding protein HU-beta\tK03530 hupB; DNA-binding protein HU-beta"
						}
						]
					}
					]
				},
				{
					"name":"SHDIR (short-homology-dependent illegitimate recombination)",
					"children":[
					{
						"name":"RecET pathway",
						"children":[
						{
							"name":"C2U53_14005 single-stranded-DNA-specific exonuclease RecJ\tK07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]"
						},
						{
							"name":"C2U53_29165 DNA repair protein RecO\tK03584 recO; DNA repair protein RecO (recombination protein O)"
						},
						{
							"name":"C2U53_16010 recombination protein RecR\tK06187 recR; recombination protein RecR"
						},
						{
							"name":"C2U53_09215 NAD-dependent DNA ligase LigB\tK01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]"
						},
						{
							"name":"C2U53_28410 ligA; NAD-dependent DNA ligase LigA\tK01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]"
						}
						]
					},
					{
						"name":"Facilitator",
						"children":[
						{
							"name":"C2U53_07010 Fis family transcriptional regulator\tK03557 fis; Fis family transcriptional regulator, factor for inversion stimulation protein"
						},
						{
							"name":"C2U53_21160 ihfA; integration host factor subunit alpha\tK04764 ihfA; integration host factor subunit alpha"
						},
						{
							"name":"C2U53_18945 ihfB; integration host factor subunit beta\tK05788 ihfB; integration host factor subunit beta"
						}
						]
					},
					{
						"name":"Supressor",
						"children":[
						{
							"name":"C2U53_26120 exodeoxyribonuclease I\tK01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]"
						},
						{
							"name":"C2U53_10300 DNA helicase RecQ\tK03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]"
						},
						{
							"name":"C2U53_11850 excinuclease ABC subunit UvrA\tK03701 uvrA; excinuclease ABC subunit A"
						},
						{
							"name":"C2U53_17535 excinuclease ABC subunit B\tK03702 uvrB; excinuclease ABC subunit B"
						},
						{
							"name":"C2U53_00455 hypothetical protein\tK03746 hns; DNA-binding protein H-NS"
						},
						{
							"name":"C2U53_02675 KorB\tK03746 hns; DNA-binding protein H-NS"
						},
						{
							"name":"C2U53_23315 DNA-binding transcriptional regulator H-NS\tK03746 hns; DNA-binding protein H-NS"
						}
						]
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"TLS (translesion DNA synthesis) factors",
			"children":[
			{
				"name":"Y-family DNA polymerases",
				"children":[
				{
					"name":"C2U53_03740 DNA polymerase IV\tK02346 dinB; DNA polymerase IV [EC:2.7.7.7]"
				},
				{
					"name":"C2U53_00225 translesion error-prone DNA polymerase V subunit UmuC\tK03502 umuC; DNA polymerase V"
				},
				{
					"name":"C2U53_00800 translesion error-prone DNA polymerase V subunit UmuC\tK03502 umuC; DNA polymerase V"
				},
				{
					"name":"C2U53_01230 translesion error-prone DNA polymerase V subunit UmuC\tK03502 umuC; DNA polymerase V"
				},
				{
					"name":"C2U53_01825 translesion error-prone DNA polymerase V subunit UmuC\tK03502 umuC; DNA polymerase V"
				},
				{
					"name":"C2U53_23790 translesion error-prone DNA polymerase V subunit UmuC\tK03502 umuC; DNA polymerase V"
				},
				{
					"name":"C2U53_00230 peptidase\tK03503 umuD; DNA polymerase V [EC:3.4.21.-]"
				},
				{
					"name":"C2U53_00805 peptidase\tK03503 umuD; DNA polymerase V [EC:3.4.21.-]"
				},
				{
					"name":"C2U53_01225 peptidase\tK03503 umuD; DNA polymerase V [EC:3.4.21.-]"
				},
				{
					"name":"C2U53_01820 translesion error-prone DNA polymerase V subunit UmuD\tK03503 umuD; DNA polymerase V [EC:3.4.21.-]"
				},
				{
					"name":"C2U53_23795 translesion error-prone DNA polymerase V subunit UmuD\tK03503 umuD; DNA polymerase V [EC:3.4.21.-]"
				},
				{
					"name":"C2U53_25665 DNA polymerase V\tK03503 umuD; DNA polymerase V [EC:3.4.21.-]"
				},
				{
					"name":"C2U53_27780 DNA polymerase V\tK03503 umuD; DNA polymerase V [EC:3.4.21.-]"
				}
				]
			},
			{
				"name":"Other SOS response factors",
				"children":[
				{
					"name":"C2U53_03335 recA; recombinase RecA\tK03553 recA; recombination protein RecA"
				},
				{
					"name":"C2U53_11680 repressor LexA\tK01356 lexA; repressor LexA [EC:3.4.21.88]"
				},
				{
					"name":"C2U53_27985 LexA family transcriptional regulator\tK01356 lexA; repressor LexA [EC:3.4.21.88]"
				},
				{
					"name":"C2U53_29425 DNA repair protein RecN\tK03631 recN; DNA repair protein RecN (Recombination protein N)"
				},
				{
					"name":"C2U53_04580 DNA polymerase II\tK02336 polB; DNA polymerase II [EC:2.7.7.7]"
				},
				{
					"name":"C2U53_00030 single-stranded DNA-binding protein\tK03111 ssb; single-strand DNA-binding protein"
				},
				{
					"name":"C2U53_01155 single-stranded DNA-binding protein\tK03111 ssb; single-strand DNA-binding protein"
				},
				{
					"name":"C2U53_01905 single-stranded DNA-binding protein\tK03111 ssb; single-strand DNA-binding protein"
				},
				{
					"name":"C2U53_11855 single-stranded DNA-binding protein SSB1\tK03111 ssb; single-strand DNA-binding protein"
				},
				{
					"name":"C2U53_20315 DNA damage-inducible protein I\tK12149 dinI; DNA-damage-inducible protein I"
				},
				{
					"name":"C2U53_03330 recombination regulator RecX\tK03565 recX; regulatory protein"
				},
				{
					"name":"C2U53_27490 ISNCY family transposase\tK24087 rpnB; recombination-promoting nuclease RpnB [EC:3.1.21.-]"
				},
				{
					"name":"C2U53_27205 ISNCY family transposase\tK24090 rpnE; recombination-promoting nuclease RpnE"
				}
				]
			}
			]
		},
		{
			"name":"Other factors with a suspected DNA repair function",
			"children":[
			{
				"name":"DNA polymerase"
			},
			{
				"name":"DNA helicases",
				"children":[
				{
					"name":"C2U53_10090 DNA helicase Rep\tK03656 rep; ATP-dependent DNA helicase Rep [EC:5.6.2.4]"
				},
				{
					"name":"C2U53_19485 DNA helicase IV\tK03658 helD; DNA helicase IV [EC:5.6.2.4]"
				},
				{
					"name":"C2U53_17665 ATP-dependent DNA helicase DinG\tK03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]"
				},
				{
					"name":"C2U53_18120 ATP-dependent DNA helicase DinG\tK03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]"
				},
				{
					"name":"C2U53_24095 ATP-dependent helicase\tK03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]"
				},
				{
					"name":"C2U53_05330 DEAD\/DEAH box helicase\tK03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]"
				},
				{
					"name":"C2U53_21550 ATP-dependent helicase\tK03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]"
				}
				]
			},
			{
				"name":"Modulation of nucleotide pools",
				"children":[
				{
					"name":"C2U53_04385 8-oxo-dGTP diphosphatase MutT\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]"
				},
				{
					"name":"C2U53_09055 dUTP diphosphatase\tK01520 dut; dUTP diphosphatase [EC:3.6.1.23]"
				},
				{
					"name":"C2U53_27160 ribonucleoside-diphosphate reductase subunit alpha\tK00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]"
				},
				{
					"name":"C2U53_29650 ribonucleotide-diphosphate reductase subunit alpha\tK00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]"
				},
				{
					"name":"C2U53_27165 ribonucleotide-diphosphate reductase subunit beta\tK00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]"
				},
				{
					"name":"C2U53_29655 nrdF; class 1b ribonucleoside-diphosphate reductase subunit beta\tK00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]"
				}
				]
			},
			{
				"name":"Others"
			}
			]
		}
		]
	}
	]
}