{
	"name":"cit03400",
	"children":[
	{
		"name":"Eukaryotic type",
		"children":[
		{
			"name":"SSBR (single strand breaks repair)",
			"children":[
			{
				"name":"Direct repair",
				"children":[
				{
					"name":"102608758 DNA oxidative demethylase ALKBH2 isoform X1\tK10859 ALKBH2; DNA oxidative demethylase [EC:1.14.11.33]"
				},
				{
					"name":"102616786 DExH-box ATP-dependent RNA helicase DExH14\tK18663 ASCC3; activating signal cointegrator complex subunit 3 [EC:5.6.2.4]"
				},
				{
					"name":"102607644 deoxyribodipyrimidine photo-lyase isoform X1\tK01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]"
				}
				]
			},
			{
				"name":"BER (base exicision repair)",
				"children":[
				{
					"name":"DNA glycosylases",
					"children":[
					{
						"name":"102619856 uracil-DNA glycosylase, mitochondrial isoform X1\tK03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]"
					},
					{
						"name":"102620793 DNA-3-methyladenine glycosylase isoform X1\tK03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]"
					},
					{
						"name":"102622215 adenine DNA glycosylase\tK03575 mutY; A\/G-specific adenine glycosylase [EC:3.2.2.31]"
					},
					{
						"name":"102607342 methyl-CpG-binding domain protein 4-like protein isoform X2\tK10801 MBD4; methyl-CpG-binding domain protein 4 [EC:3.2.2.-]"
					},
					{
						"name":"102614909 N-glycosylase\/DNA lyase OGG1\tK03660 OGG1; N-glycosylase\/DNA lyase [EC:3.2.2.- 4.2.99.18]"
					},
					{
						"name":"102616863 endonuclease III homolog 1, chloroplastic-like isoform X1\tK10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]"
					},
					{
						"name":"102617365 endonuclease III homolog 1, chloroplastic-like isoform X1\tK10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]"
					},
					{
						"name":"102627550 putative DNA glycosylase At3g47830 isoform X1\tK10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]"
					}
					]
				},
				{
					"name":"AP endonucleases",
					"children":[
					{
						"name":"102619750 DNA-(apurinic or apyrimidinic site) endonuclease 2 isoform X1\tK10772 APEX2; AP endonuclease 2 [EC:3.1.11.2]"
					}
					]
				},
				{
					"name":"Long Patch-BER factors",
					"children":[
					{
						"name":"DNA polymerase delta complex",
						"children":[
						{
							"name":"102612202 DNA polymerase delta catalytic subunit\tK02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]"
						},
						{
							"name":"102626465 DNA polymerase delta small subunit isoform X3\tK02328 POLD2; DNA polymerase delta subunit 2"
						},
						{
							"name":"102608043 uncharacterized protein LOC102608043\tK03504 POLD3; DNA polymerase delta subunit 3"
						},
						{
							"name":"102608934 uncharacterized protein LOC102608934\tK03505 POLD4; DNA polymerase delta subunit 4"
						}
						]
					},
					{
						"name":"DNA polymerase epsilon complex",
						"children":[
						{
							"name":"102608212 DNA polymerase epsilon catalytic subunit A-like isoform X1\tK02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]"
						},
						{
							"name":"102610782 DNA polymerase epsilon subunit B\tK02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]"
						},
						{
							"name":"102618948 DNA polymerase II subunit B4 isoform X1\tK02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]"
						}
						]
					},
					{
						"name":"102627400 proliferating cell nuclear antigen\tK04802 PCNA; proliferating cell nuclear antigen"
					},
					{
						"name":"102618340 flap endonuclease 1 isoform X3\tK04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]"
					},
					{
						"name":"102628869 DNA ligase 1\tK10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]"
					}
					]
				},
				{
					"name":"Short Patch-BER factors",
					"children":[
					{
						"name":"102609129 DNA-repair protein XRCC1 isoform X1\tK10803 XRCC1; DNA-repair protein XRCC1"
					}
					]
				},
				{
					"name":"Other BER factors",
					"children":[
					{
						"name":"102627995 tyrosyl-DNA phosphodiesterase 1\tK10862 TDP1; tyrosyl-DNA phosphodiesterase 1 [EC:3.1.4.-]"
					},
					{
						"name":"102619121 transcription factor bHLH140 isoform X1\tK10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]"
					},
					{
						"name":"102622568 polynucleotide 3'-phosphatase ZDP isoform X2\tK08073 PNKP; bifunctional polynucleotide phosphatase\/kinase [EC:3.1.3.32 2.7.1.78]"
					},
					{
						"name":"102620577 DNA polymerase lambda isoform X1\tK03512 POLL; DNA polymerase lambda [EC:2.7.7.7 4.2.99.-]"
					},
					{
						"name":"102621976 poly [ADP-ribose] polymerase 1\tK24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30]"
					},
					{
						"name":"102609012 poly [ADP-ribose] polymerase 2-like isoform X1\tK28005 PARP2; poly [ADP-ribose] polymerase 2 [EC:2.4.2.30]"
					},
					{
						"name":"102625457 LOW QUALITY PROTEIN: poly [ADP-ribose] polymerase 2-like\tK28005 PARP2; poly [ADP-ribose] polymerase 2 [EC:2.4.2.30]"
					},
					{
						"name":"102620309 LOW QUALITY PROTEIN: protein ADP-ribosyltransferase PARP3\tK10798 PARP3_4; protein mono-ADP-ribosyltransferase 3\/4 [EC:2.4.2.-]"
					}
					]
				}
				]
			},
			{
				"name":"NER (nucleotide excision repair)",
				"children":[
				{
					"name":"GGR (global genome repair) factors",
					"children":[
					{
						"name":"XPC-HR23B-CETN2 complex",
						"children":[
						{
							"name":"102619998 DNA repair protein RAD4 isoform X1\tK10838 XPC; xeroderma pigmentosum group C-complementing protein"
						},
						{
							"name":"102610300 ubiquitin receptor RAD23d-like\tK10839 RAD23; UV excision repair protein RAD23"
						},
						{
							"name":"102614644 ubiquitin receptor RAD23c-like isoform X1\tK10839 RAD23; UV excision repair protein RAD23"
						},
						{
							"name":"102620700 ubiquitin receptor RAD23b\tK10839 RAD23; UV excision repair protein RAD23"
						}
						]
					},
					{
						"name":"Cul4-DDB2 complex",
						"children":[
						{
							"name":"102613162 RING-box protein 1A\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
						},
						{
							"name":"102622192 uncharacterized protein LOC102622192\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
						},
						{
							"name":"102612108 cullin-4 isoform X1\tK10609 CUL4; cullin 4"
						},
						{
							"name":"102623596 DNA damage-binding protein 1a isoform X1\tK10610 DDB1; DNA damage-binding protein 1"
						},
						{
							"name":"102616830 protein DAMAGED DNA-BINDING 2\tK10140 DDB2; DNA damage-binding protein 2"
						}
						]
					},
					{
						"name":"NER4 complex",
						"children":[
						{
							"name":"102618421 uncharacterized protein LOC102618421\tK15082 RAD7; DNA repair protein RAD7"
						},
						{
							"name":"102618698 uncharacterized protein LOC102618698\tK15082 RAD7; DNA repair protein RAD7"
						},
						{
							"name":"102630106 ATP-dependent helicase rhp16 isoform X1\tK15083 RAD16; DNA repair protein RAD16"
						}
						]
					}
					]
				},
				{
					"name":"TCR (transcription coupled repair) factors",
					"children":[
					{
						"name":"DNA-directed RNA polymerase II complex",
						"children":[
						{
							"name":"102617026 DNA-directed RNA polymerase II subunit RPB1\tK03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]"
						},
						{
							"name":"102617803 DNA-directed RNA polymerase II subunit RPB2\tK03010 RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]"
						},
						{
							"name":"102612811 DNA-directed RNA polymerases II, IV and V subunit 3\tK03011 RPB3; DNA-directed RNA polymerase II subunit RPB3"
						},
						{
							"name":"102621370 DNA-directed RNA polymerase II subunit 4\tK03012 RPB4; DNA-directed RNA polymerase II subunit RPB4"
						},
						{
							"name":"102623007 DNA-directed RNA polymerases IV and V subunit 4 isoform X1\tK03012 RPB4; DNA-directed RNA polymerase II subunit RPB4"
						},
						{
							"name":"102611161 DNA-directed RNA polymerase V subunit 5A isoform X1\tK03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1"
						},
						{
							"name":"102612864 DNA-directed RNA polymerase V subunit 5C isoform X1\tK03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1"
						},
						{
							"name":"102629940 DNA-directed RNA polymerases II and IV subunit 5A\tK03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1"
						},
						{
							"name":"102623212 DNA-directed RNA polymerases II, IV and V subunit 6A\tK03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2"
						},
						{
							"name":"102612216 DNA-directed RNA polymerase II subunit RPB7\tK03015 RPB7; DNA-directed RNA polymerase II subunit RPB7"
						},
						{
							"name":"102613961 DNA-directed RNA polymerases II, IV and V subunit 8B-like\tK03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3"
						},
						{
							"name":"102625354 DNA-directed RNA polymerases II and V subunit 8A\tK03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3"
						},
						{
							"name":"102623490 DNA-directed RNA polymerases II, IV and V subunit 9A\tK03017 RPB9; DNA-directed RNA polymerase II subunit RPB9"
						},
						{
							"name":"102624903 DNA-directed RNA polymerase subunit 10-like protein\tK03007 RPABC5; DNA-directed RNA polymerases I, II, and III subunit RPABC5"
						},
						{
							"name":"102612486 DNA-directed RNA polymerases II, IV and V subunit 11 isoform X1\tK03008 RPB11; DNA-directed RNA polymerase II subunit RPB11"
						},
						{
							"name":"102608086 DNA-directed RNA polymerases II, IV and V subunit 12\tK03009 RPABC4; DNA-directed RNA polymerases I, II, and III subunit RPABC4"
						}
						]
					},
					{
						"name":"Cul4-CSA complex",
						"children":[
						{
							"name":"102613162 RING-box protein 1A\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
						},
						{
							"name":"102622192 uncharacterized protein LOC102622192\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
						},
						{
							"name":"102612108 cullin-4 isoform X1\tK10609 CUL4; cullin 4"
						},
						{
							"name":"102623596 DNA damage-binding protein 1a isoform X1\tK10610 DDB1; DNA damage-binding protein 1"
						},
						{
							"name":"102614817 WD repeat-containing protein ATCSA-1-like isoform X1\tK10570 ERCC8; DNA excision repair protein ERCC-8"
						}
						]
					},
					{
						"name":"Other TCR factor",
						"children":[
						{
							"name":"102607652 protein CHROMATIN REMODELING 8 isoform X1\tK10841 ERCC6; DNA excision repair protein ERCC-6"
						},
						{
							"name":"102624271 UV-stimulated scaffold protein A homolog\tK23720 UVSSA; UV-stimulated scaffold protein A"
						},
						{
							"name":"127901204 UV-stimulated scaffold protein A homolog\tK23720 UVSSA; UV-stimulated scaffold protein A"
						},
						{
							"name":"102628584 transcription elongation factor 1 homolog\tK25829 ELOF1; transcription elongation factor 1"
						}
						]
					}
					]
				},
				{
					"name":"TFIIH complex",
					"children":[
					{
						"name":"102621673 general transcription and DNA repair factor IIH helicase subunit XPB1\tK10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]"
					},
					{
						"name":"102618714 general transcription and DNA repair factor IIH helicase subunit XPD\tK10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]"
					},
					{
						"name":"102606944 general transcription and DNA repair factor IIH subunit TFB1-1\tK03141 TFIIH1; transcription initiation factor TFIIH subunit 1"
					},
					{
						"name":"102608574 general transcription factor IIH subunit 2\tK03142 TFIIH2; transcription initiation factor TFIIH subunit 2"
					},
					{
						"name":"102629138 general transcription factor IIH subunit 2-like\tK03142 TFIIH2; transcription initiation factor TFIIH subunit 2"
					},
					{
						"name":"102625253 general transcription and DNA repair factor IIH subunit TFB4 isoform X1\tK03143 TFIIH3; transcription initiation factor TFIIH subunit 3"
					},
					{
						"name":"102607298 general transcription and DNA repair factor IIH subunit TFB2 isoform X1\tK03144 TFIIH4; transcription initiation factor TFIIH subunit 4"
					},
					{
						"name":"102608810 general transcription and DNA repair factor IIH subunit TFB2-like\tK03144 TFIIH4; transcription initiation factor TFIIH subunit 4"
					},
					{
						"name":"102612060 general transcription and DNA repair factor IIH subunit TFB5\tK10845 TTDA; TFIIH basal transcription factor complex TTD-A subunit"
					},
					{
						"name":"102629347 cyclin-dependent kinase D-3\tK02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]"
					},
					{
						"name":"102628605 cyclin-H1-1 isoform X1\tK06634 CCNH; cyclin H"
					},
					{
						"name":"102617561 uncharacterized protein LOC102617561\tK10842 MNAT1; CDK-activating kinase assembly factor MAT1"
					}
					]
				},
				{
					"name":"RPA (replication factor A)",
					"children":[
					{
						"name":"102611437 replication protein A 70 kDa DNA-binding subunit A isoform X1\tK07466 RFA1; replication factor A1"
					},
					{
						"name":"102626079 replication protein A 70 kDa DNA-binding subunit A\tK07466 RFA1; replication factor A1"
					},
					{
						"name":"102626798 replication protein A 70 kDa DNA-binding subunit B\tK07466 RFA1; replication factor A1"
					},
					{
						"name":"102610567 replication protein A 32 kDa subunit B isoform X1\tK10739 RFA2; replication factor A2"
					},
					{
						"name":"102610707 replication protein A 32 kDa subunit A\tK10739 RFA2; replication factor A2"
					},
					{
						"name":"102619411 replication protein A 14 kDa subunit B\tK10740 RPA3; replication factor A3"
					}
					]
				},
				{
					"name":"Other NER factors",
					"children":[
					{
						"name":"102623615 DNA excision repair protein ERCC-1 isoform X1\tK10849 ERCC1; DNA excision repair protein ERCC-1"
					},
					{
						"name":"102624221 DNA repair endonuclease UVH1 isoform X1\tK10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]"
					},
					{
						"name":"102606724 DNA repair protein UVH3 isoform X1\tK10846 ERCC5; DNA excision repair protein ERCC-5"
					},
					{
						"name":"102628869 DNA ligase 1\tK10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]"
					},
					{
						"name":"102610725 MMS19 nucleotide excision repair protein homolog isoform X2\tK15075 MET18; DNA repair\/transcription protein MET18\/MMS19"
					},
					{
						"name":"102625463 protein CIA1\tK24730 CIAO1; cytosolic iron-sulfur protein assembly protein CIAO1"
					},
					{
						"name":"102621935 protein AE7\tK26403 CIAO2; cytosolic iron-sulfur assembly component 2"
					},
					{
						"name":"102625666 protein AE7-like 1\tK26403 CIAO2; cytosolic iron-sulfur assembly component 2"
					},
					{
						"name":"102622384 cullin-3A\tK03869 CUL3; cullin 3"
					},
					{
						"name":"102630361 cullin-3B-like\tK03869 CUL3; cullin 3"
					},
					{
						"name":"102614386 uncharacterized protein LOC102614386\tK03872 ELOC; elongin-C"
					},
					{
						"name":"102618508 uncharacterized protein LOC102618508\tK03873 ELOB; elongin-B"
					},
					{
						"name":"102629354 uncharacterized protein LOC102629354\tK15077 ELA1; elongin-A"
					}
					]
				}
				]
			},
			{
				"name":"MMR (mismatch excision repair)",
				"children":[
				{
					"name":"Mismatch and loop recognition factors",
					"children":[
					{
						"name":"102614656 DNA mismatch repair protein MSH2\tK08735 MSH2; DNA mismatch repair protein MSH2"
					},
					{
						"name":"102630910 DNA mismatch repair protein MSH3\tK08736 MSH3; DNA mismatch repair protein MSH3"
					},
					{
						"name":"102617856 DNA mismatch repair protein MSH7\tK08737 MSH6; DNA mismatch repair protein MSH6"
					},
					{
						"name":"102627728 DNA mismatch repair protein MSH6\tK08737 MSH6; DNA mismatch repair protein MSH6"
					}
					]
				},
				{
					"name":"MutL homologs",
					"children":[
					{
						"name":"102610589 DNA mismatch repair protein MLH1\tK08734 MLH1; DNA mismatch repair protein MLH1"
					},
					{
						"name":"102625172 DNA mismatch repair protein PMS1 isoform X1\tK10858 PMS2; DNA mismatch repair protein PMS2"
					},
					{
						"name":"102608669 DNA mismatch repair protein MLH3 isoform X2\tK08739 MLH3; DNA mismatch repair protein MLH3"
					}
					]
				},
				{
					"name":"DNA polymerase delta complex",
					"children":[
					{
						"name":"102612202 DNA polymerase delta catalytic subunit\tK02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]"
					},
					{
						"name":"102626465 DNA polymerase delta small subunit isoform X3\tK02328 POLD2; DNA polymerase delta subunit 2"
					},
					{
						"name":"102608043 uncharacterized protein LOC102608043\tK03504 POLD3; DNA polymerase delta subunit 3"
					},
					{
						"name":"102608934 uncharacterized protein LOC102608934\tK03505 POLD4; DNA polymerase delta subunit 4"
					}
					]
				},
				{
					"name":"RPA (replication factor A)",
					"children":[
					{
						"name":"102611437 replication protein A 70 kDa DNA-binding subunit A isoform X1\tK07466 RFA1; replication factor A1"
					},
					{
						"name":"102626079 replication protein A 70 kDa DNA-binding subunit A\tK07466 RFA1; replication factor A1"
					},
					{
						"name":"102626798 replication protein A 70 kDa DNA-binding subunit B\tK07466 RFA1; replication factor A1"
					},
					{
						"name":"102610567 replication protein A 32 kDa subunit B isoform X1\tK10739 RFA2; replication factor A2"
					},
					{
						"name":"102610707 replication protein A 32 kDa subunit A\tK10739 RFA2; replication factor A2"
					},
					{
						"name":"102619411 replication protein A 14 kDa subunit B\tK10740 RPA3; replication factor A3"
					}
					]
				},
				{
					"name":"RFC (replication factor C)",
					"children":[
					{
						"name":"102623585 replication factor C subunit 1\tK10754 RFC1; replication factor C subunit 1"
					},
					{
						"name":"102616275 replication factor C subunit 4 isoform X1\tK10755 RFC2_4; replication factor C subunit 2\/4"
					},
					{
						"name":"102617383 replication factor C subunit 2\tK10755 RFC2_4; replication factor C subunit 2\/4"
					},
					{
						"name":"102609520 uncharacterized protein LOC102609520\tK10756 RFC3_5; replication factor C subunit 3\/5"
					},
					{
						"name":"102612743 replication factor C subunit 3\tK10756 RFC3_5; replication factor C subunit 3\/5"
					},
					{
						"name":"102615422 replication factor C subunit 3\tK10756 RFC3_5; replication factor C subunit 3\/5"
					},
					{
						"name":"102625196 replication factor C subunit 3-like\tK10756 RFC3_5; replication factor C subunit 3\/5"
					}
					]
				},
				{
					"name":"Other MMR factors",
					"children":[
					{
						"name":"102627400 proliferating cell nuclear antigen\tK04802 PCNA; proliferating cell nuclear antigen"
					},
					{
						"name":"102615179 exonuclease 1\tK10746 EXO1; exonuclease 1 [EC:3.1.-.-]"
					},
					{
						"name":"102616157 exonuclease 1\tK10746 EXO1; exonuclease 1 [EC:3.1.-.-]"
					},
					{
						"name":"102628869 DNA ligase 1\tK10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]"
					},
					{
						"name":"102622839 DNA damage-binding protein cmr1\tK24755 WDR76; WD repeat-containing protein 76"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"DSBR (double strand breaks repair)",
			"children":[
			{
				"name":"HR (homologous recombination)",
				"children":[
				{
					"name":"MRN(MRX) complex",
					"children":[
					{
						"name":"102624634 double-strand break repair protein MRE11 isoform X2\tK10865 MRE11; double-strand break repair protein MRE11"
					},
					{
						"name":"102616752 DNA repair protein RAD50 isoform X1\tK10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]"
					},
					{
						"name":"102614559 nibrin homolog\tK10867 NBN; nibrin"
					}
					]
				},
				{
					"name":"BRCA1-core complex",
					"children":[
					{
						"name":"102622461 BRCA1-associated RING domain protein 1 isoform X2\tK10683 BARD1; BRCA1-associated RING domain protein 1"
					},
					{
						"name":"102626843 protein BREAST CANCER SUSCEPTIBILITY 1 homolog isoform X1\tK10683 BARD1; BRCA1-associated RING domain protein 1"
					}
					]
				},
				{
					"name":"BRCA1-A complex",
					"children":[
					{
						"name":"102611871 uncharacterized protein LOC102611871\tK20776 BABAM; BRISC and BRCA1-A complex member 1"
					},
					{
						"name":"102631455 uncharacterized protein LOC102631455\tK12173 BRE; BRCA1-A complex subunit BRE"
					},
					{
						"name":"102613692 uncharacterized protein LOC102613692 isoform X1\tK11864 BRCC3; BRCA1\/BRCA2-containing complex subunit 3 [EC:3.4.19.-]"
					}
					]
				},
				{
					"name":"BRCA1-B complex",
					"children":[
					{
						"name":"102620438 uncharacterized protein LOC102620438 isoform X1\tK15362 BRIP1; fanconi anemia group J protein [EC:5.6.2.3]"
					},
					{
						"name":"102622944 uncharacterized protein LOC102622944 isoform X1\tK10728 TOPBP1; topoisomerase (DNA) II binding protein 1"
					},
					{
						"name":"102624568 BRCT domain-containing protein At4g02110 isoform X1\tK10728 TOPBP1; topoisomerase (DNA) II binding protein 1"
					}
					]
				},
				{
					"name":"BRCA1-C complex",
					"children":[
					{
						"name":"102624634 double-strand break repair protein MRE11 isoform X2\tK10865 MRE11; double-strand break repair protein MRE11"
					},
					{
						"name":"102616752 DNA repair protein RAD50 isoform X1\tK10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]"
					},
					{
						"name":"102614559 nibrin homolog\tK10867 NBN; nibrin"
					}
					]
				},
				{
					"name":"BRCA complex",
					"children":[
					{
						"name":"102628548 protein BREAST CANCER SUSCEPTIBILITY 2 homolog B-like\tK08775 BRCA2; breast cancer 2 susceptibility protein"
					},
					{
						"name":"102610570 DNA repair protein RAD51 homolog\tK04482 RAD51; DNA repair protein RAD51"
					}
					]
				},
				{
					"name":"RecA family proteins",
					"children":[
					{
						"name":"102610570 DNA repair protein RAD51 homolog\tK04482 RAD51; DNA repair protein RAD51"
					},
					{
						"name":"102610213 DNA repair protein RAD51 homolog 2 isoform X1\tK10869 RAD51L1; RAD51-like protein 1"
					},
					{
						"name":"102619562 DNA repair protein RAD51 homolog 3 isoform X1\tK10870 RAD51L2; RAD51-like protein 2"
					},
					{
						"name":"102607526 DNA repair protein XRCC3 homolog\tK10880 XRCC3; DNA-repair protein XRCC3"
					}
					]
				},
				{
					"name":"Rad52 family proteins",
					"children":[
					{
						"name":"102615229 DNA repair RAD52-like protein 1, mitochondrial\tK26556 RAD52-1; DNA repair RAD52-like protein 1, mitochondrial"
					},
					{
						"name":"102625430 DNA repair RAD52-like protein 2, chloroplastic\tK26558 RAD52-2; DNA repair RAD52-like protein 2, chloroplastic"
					}
					]
				},
				{
					"name":"Rad54 family proteins",
					"children":[
					{
						"name":"102610506 SNF2 domain-containing protein CLASSY 1-like\tK10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]"
					},
					{
						"name":"102611707 SNF2 domain-containing protein CLASSY 1-like\tK10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]"
					},
					{
						"name":"102613667 SNF2 domain-containing protein CLASSY 3-like\tK10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]"
					},
					{
						"name":"102614093 protein CHROMATIN REMODELING 25 isoform X2\tK10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]"
					},
					{
						"name":"102625289 protein CHROMATIN REMODELING 35\tK10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]"
					}
					]
				},
				{
					"name":"RecQ family DNA helicases",
					"children":[
					{
						"name":"102615882 ATP-dependent DNA helicase Q-like 1 isoform X1\tK10899 RECQL; ATP-dependent DNA helicase Q1 [EC:5.6.2.4]"
					},
					{
						"name":"102630216 ATP-dependent DNA helicase Q-like 2 isoform X1\tK10899 RECQL; ATP-dependent DNA helicase Q1 [EC:5.6.2.4]"
					},
					{
						"name":"102608985 ATP-dependent DNA helicase Q-like SIM isoform X4\tK10900 WRN; werner syndrome ATP-dependent helicase [EC:5.6.2.4]"
					},
					{
						"name":"102610752 ATP-dependent DNA helicase Q-like 4A isoform X1\tK10901 BLM; bloom syndrome protein [EC:5.6.2.4]"
					},
					{
						"name":"102620027 ATP-dependent DNA helicase Q-like 3\tK10901 BLM; bloom syndrome protein [EC:5.6.2.4]"
					},
					{
						"name":"102618543 ATP-dependent DNA helicase Q-like 5\tK10730 RECQL4; ATP-dependent DNA helicase Q4 [EC:5.6.2.4]"
					}
					]
				},
				{
					"name":"Bloom's syndrome complex (BTR)",
					"children":[
					{
						"name":"102610752 ATP-dependent DNA helicase Q-like 4A isoform X1\tK10901 BLM; bloom syndrome protein [EC:5.6.2.4]"
					},
					{
						"name":"102620027 ATP-dependent DNA helicase Q-like 3\tK10901 BLM; bloom syndrome protein [EC:5.6.2.4]"
					},
					{
						"name":"102617834 DNA topoisomerase 3-beta\tK03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]"
					},
					{
						"name":"102618169 DNA topoisomerase 3-alpha\tK03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]"
					},
					{
						"name":"102624575 RecQ-mediated genome instability protein 1\tK10990 RMI1; RecQ-mediated genome instability protein 1"
					},
					{
						"name":"102607469 uncharacterized protein LOC102607469\tK15365 RMI2; RecQ-mediated genome instability protein 2"
					}
					]
				},
				{
					"name":"RPA (replication factor A)",
					"children":[
					{
						"name":"102611437 replication protein A 70 kDa DNA-binding subunit A isoform X1\tK07466 RFA1; replication factor A1"
					},
					{
						"name":"102626079 replication protein A 70 kDa DNA-binding subunit A\tK07466 RFA1; replication factor A1"
					},
					{
						"name":"102626798 replication protein A 70 kDa DNA-binding subunit B\tK07466 RFA1; replication factor A1"
					},
					{
						"name":"102610567 replication protein A 32 kDa subunit B isoform X1\tK10739 RFA2; replication factor A2"
					},
					{
						"name":"102610707 replication protein A 32 kDa subunit A\tK10739 RFA2; replication factor A2"
					},
					{
						"name":"102619411 replication protein A 14 kDa subunit B\tK10740 RPA3; replication factor A3"
					}
					]
				},
				{
					"name":"Protein phosphatase 4",
					"children":[
					{
						"name":"102608319 serine\/threonine-protein phosphatase PP-X isozyme 2\tK15423 PPP4C; serine\/threonine-protein phosphatase 4 catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"102608047 uncharacterized protein LOC102608047 isoform X1\tK15425 PPP4R2; serine\/threonine-protein phosphatase 4 regulatory subunit 2"
					},
					{
						"name":"102624367 uncharacterized protein LOC102624367 isoform X1\tK17491 SMEK; protein phosphatase 4 regulatory subunit 3"
					}
					]
				},
				{
					"name":"AP-5 complex",
					"children":[
					{
						"name":"102614078 uncharacterized protein LOC102614078 isoform X1\tK19022 AP5B1; AP-5 complex subunit beta-1"
					},
					{
						"name":"102630193 AP-5 complex subunit mu\tK19023 AP5M1; AP-5 complex subunit mu-1"
					},
					{
						"name":"102611754 uncharacterized protein LOC102611754 isoform X1\tK19025 AP5Z1; AP-5 complex subunit zeta-1"
					}
					]
				},
				{
					"name":"SMC5-SMC6 complex",
					"children":[
					{
						"name":"102630865 structural maintenance of chromosomes protein 5 isoform X1\tK22803 SMC5; structural maintenance of chromosomes protein 5"
					},
					{
						"name":"102612928 structural maintenance of chromosomes protein 6B-like\tK22804 SMC6; structural maintenance of chromosomes protein 6"
					},
					{
						"name":"102625235 uncharacterized protein LOC102625235\tK22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27]"
					},
					{
						"name":"102618942 E3 SUMO-protein ligase MMS21\tK22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]"
					},
					{
						"name":"102609635 non-structural maintenance of chromosomes element 4 homolog A\tK22825 NSMCE4; non-structural maintenance of chromosomes element 4"
					},
					{
						"name":"102620982 non-structural maintenance of chromosomes element 4 homolog A-like isoform X1\tK22825 NSMCE4; non-structural maintenance of chromosomes element 4"
					}
					]
				},
				{
					"name":"Other HR factors",
					"children":[
					{
						"name":"102608362 crossover junction endonuclease EME1B-like\tK10882 EME1; crossover junction endonuclease EME1 [EC:3.1.22.-]"
					},
					{
						"name":"102619228 crossover junction endonuclease MUS81 isoform X1\tK08991 MUS81; crossover junction endonuclease MUS81 [EC:3.1.22.-]"
					},
					{
						"name":"102613664 protein DSS1 HOMOLOG ON CHROMOSOME V\tK10881 SHFM1; 26 proteasome complex subunit DSS1"
					},
					{
						"name":"102626954 protein DSS1 HOMOLOG ON CHROMOSOME V-like\tK10881 SHFM1; 26 proteasome complex subunit DSS1"
					},
					{
						"name":"102609773 structure-specific endonuclease subunit slx1\tK15078 SLX1; structure-specific endonuclease subunit SLX1 [EC:3.6.1.-]"
					},
					{
						"name":"102631105 uncharacterized protein LOC102631105\tK15078 SLX1; structure-specific endonuclease subunit SLX1 [EC:3.6.1.-]"
					},
					{
						"name":"102621447 flap endonuclease GEN-like 1 isoform X1\tK15338 GEN1; holliday junction resolvase GEN1\/YEN1 [EC:3.1.-.-]"
					},
					{
						"name":"102631209 single-strand DNA endonuclease 1 isoform X1\tK15338 GEN1; holliday junction resolvase GEN1\/YEN1 [EC:3.1.-.-]"
					},
					{
						"name":"127898610 flap endonuclease GEN-like 1 isoform X1\tK15338 GEN1; holliday junction resolvase GEN1\/YEN1 [EC:3.1.-.-]"
					},
					{
						"name":"102626916 uncharacterized protein LOC102626916 isoform X1\tK19026 SPG11; spatacsin"
					},
					{
						"name":"102622154 uncharacterized protein LOC102622154 isoform X1\tK19027 ZFYVE26; zinc finger FYVE domain-containing protein 26"
					},
					{
						"name":"102619381 protein MRG2-like isoform X1\tK11339 MORF4L1; mortality factor 4-like protein 1"
					},
					{
						"name":"102625664 protein MRG1 isoform X1\tK11339 MORF4L1; mortality factor 4-like protein 1"
					},
					{
						"name":"102611224 uncharacterized protein LOC102611224 isoform X2\tK22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-]"
					},
					{
						"name":"102623512 uncharacterized protein LOC102623512\tK22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-]"
					},
					{
						"name":"102630504 ATPase family AAA domain-containing protein FIGL1\tK22766 FIGNL1; fidgetin-like protein 1 [EC:5.6.2.-]"
					},
					{
						"name":"102617416 uncharacterized protein LOC102617416\tK25770 ZSWIM7; zinc finger SWIM domain-containing protein 7"
					},
					{
						"name":"102620779 uncharacterized protein LOC102620779 isoform X2\tK27803 HROB; homologous recombination OB-fold protein"
					},
					{
						"name":"102628058 probable DNA helicase MCM8\tK10737 MCM8; DNA helicase MCM8 [EC:5.6.2.4]"
					},
					{
						"name":"102623036 probable DNA helicase MCM9\tK10738 MCM9; DNA helicase MCM9 [EC:5.6.2.4]"
					},
					{
						"name":"102628781 uncharacterized protein LOC102628781 isoform X1\tK15047 HNRNPUL1; heterogeneous nuclear ribonucleoprotein U-like protein 1"
					},
					{
						"name":"102615213 uncharacterized protein LOC102615213 isoform X1\tK28623 MRNIP; MRN complex-interacting protein"
					},
					{
						"name":"102620551 DNA-dependent metalloprotease WSS1\tK22685 WSS1; DNA-dependent metalloprotease WSS1 [EC:3.4.24.-]"
					},
					{
						"name":"102625257 DNA-dependent metalloprotease WSS1-like\tK22685 WSS1; DNA-dependent metalloprotease WSS1 [EC:3.4.24.-]"
					},
					{
						"name":"102610089 single-stranded DNA-binding protein WHY1, chloroplastic\tK26559 WHY1; single-stranded DNA-binding protein WHY1"
					},
					{
						"name":"102613455 single-stranded DNA-binding protein WHY2, mitochondrial isoform X1\tK26561 WHY2; single-stranded DNA-binding protein WHY2"
					}
					]
				}
				]
			},
			{
				"name":"NHEJ (non-homologous end-joining)",
				"children":[
				{
					"name":"DNA-PK complex",
					"children":[
					{
						"name":"102627949 ATP-dependent DNA helicase 2 subunit KU70\tK10884 XRCC6; ATP-dependent DNA helicase 2 subunit 1"
					},
					{
						"name":"102626662 ATP-dependent DNA helicase 2 subunit KU80 isoform X1\tK10885 XRCC5; ATP-dependent DNA helicase 2 subunit 2"
					}
					]
				},
				{
					"name":"MRX complex",
					"children":[
					{
						"name":"102624634 double-strand break repair protein MRE11 isoform X2\tK10865 MRE11; double-strand break repair protein MRE11"
					},
					{
						"name":"102616752 DNA repair protein RAD50 isoform X1\tK10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]"
					}
					]
				},
				{
					"name":"DNA Ligase 4 complex",
					"children":[
					{
						"name":"102608121 DNA ligase 4\tK10777 LIG4; DNA ligase 4 [EC:6.5.1.1]"
					},
					{
						"name":"102621916 DNA repair protein XRCC4 isoform X3\tK10886 XRCC4; DNA-repair protein XRCC4"
					}
					]
				},
				{
					"name":"X-family DNA polymerases",
					"children":[
					{
						"name":"102620577 DNA polymerase lambda isoform X1\tK03512 POLL; DNA polymerase lambda [EC:2.7.7.7 4.2.99.-]"
					}
					]
				},
				{
					"name":"Other NHEJ factors",
					"children":[
					{
						"name":"102619121 transcription factor bHLH140 isoform X1\tK10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]"
					},
					{
						"name":"102625567 uncharacterized protein LOC102625567 isoform X1\tK19619 TDP2; tyrosyl-DNA phosphodiesterase 2 [EC:3.1.4.-]"
					},
					{
						"name":"102628315 structural maintenance of chromosomes flexible hinge domain-containing protein GMI1\tK23113 SMCHD1; structural maintenance of chromosomes flexible hinge domain-containing protein 1"
					}
					]
				}
				]
			},
			{
				"name":"FA (Fanconi anemia) pathway",
				"children":[
				{
					"name":"FA core complex",
					"children":[
					{
						"name":"102612512 uncharacterized protein LOC102612512 isoform X1\tK10606 FANCL; E3 ubiquitin-protein ligase FANCL [EC:2.3.2.27]"
					},
					{
						"name":"102619291 DEAD-box ATP-dependent RNA helicase FANCM isoform X1\tK10896 FANCM; fanconi anemia group M protein"
					}
					]
				},
				{
					"name":"FA core complex binding factors",
					"children":[
					{
						"name":"102627384 protein MHF1 homolog\tK11511 APITD1; centromere protein S"
					},
					{
						"name":"102609861 protein MHF2 homolog\tK15360 STRA13; centromere protein X"
					},
					{
						"name":"102615715 uncharacterized protein LOC102615715\tK13960 UBE2T; ubiquitin-conjugating enzyme E2 T [EC:2.3.2.23]"
					}
					]
				},
				{
					"name":"Bloom's syndrome complex (BTR)",
					"children":[
					{
						"name":"102610752 ATP-dependent DNA helicase Q-like 4A isoform X1\tK10901 BLM; bloom syndrome protein [EC:5.6.2.4]"
					},
					{
						"name":"102620027 ATP-dependent DNA helicase Q-like 3\tK10901 BLM; bloom syndrome protein [EC:5.6.2.4]"
					},
					{
						"name":"102617834 DNA topoisomerase 3-beta\tK03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]"
					},
					{
						"name":"102618169 DNA topoisomerase 3-alpha\tK03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]"
					},
					{
						"name":"102624575 RecQ-mediated genome instability protein 1\tK10990 RMI1; RecQ-mediated genome instability protein 1"
					},
					{
						"name":"102607469 uncharacterized protein LOC102607469\tK15365 RMI2; RecQ-mediated genome instability protein 2"
					}
					]
				},
				{
					"name":"FANCD2-I complex",
					"children":[
					{
						"name":"102616403 uncharacterized protein LOC102616403\tK10891 FANCD2; fanconi anemia group D2 protein"
					},
					{
						"name":"102608856 uncharacterized protein LOC102608856 isoform X1\tK10895 FANCI; fanconi anemia group I protein"
					}
					]
				},
				{
					"name":"Downstream FA components",
					"children":[
					{
						"name":"102628548 protein BREAST CANCER SUSCEPTIBILITY 2 homolog B-like\tK08775 BRCA2; breast cancer 2 susceptibility protein"
					},
					{
						"name":"102620438 uncharacterized protein LOC102620438 isoform X1\tK15362 BRIP1; fanconi anemia group J protein [EC:5.6.2.3]"
					}
					]
				},
				{
					"name":"Other FA pathway factors",
					"children":[
					{
						"name":"102614903 fanconi-associated nuclease 1 homolog isoform X1\tK15363 FAN1; fanconi-associated nuclease 1 [EC:3.1.21.- 3.1.4.1]"
					},
					{
						"name":"102610570 DNA repair protein RAD51 homolog\tK04482 RAD51; DNA repair protein RAD51"
					},
					{
						"name":"102619562 DNA repair protein RAD51 homolog 3 isoform X1\tK10870 RAD51L2; RAD51-like protein 2"
					},
					{
						"name":"102620559 uncharacterized protein LOC102620559\tK11137 TELO2; telomere length regulation protein"
					},
					{
						"name":"102621542 uncharacterized protein LOC102621542\tK15361 WDR48; WD repeat-containing protein 48"
					}
					]
				}
				]
			},
			{
				"name":"Other DSBR factors",
				"children":[
				{
					"name":"Protein phosphatase 6",
					"children":[
					{
						"name":"102615860 phytochrome-associated serine\/threonine-protein phosphatase\tK15498 PPP6C; serine\/threonine-protein phosphatase 6 catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"102623773 uncharacterized protein LOC102623773 isoform X1\tK15501 PPP6R3; serine\/threonine-protein phosphatase 6 regulatory subunit 3"
					},
					{
						"name":"102629725 uncharacterized protein LOC102629725 isoform X2\tK15501 PPP6R3; serine\/threonine-protein phosphatase 6 regulatory subunit 3"
					}
					]
				},
				{
					"name":"Ubiquitin ligases"
				},
				{
					"name":"Others",
					"children":[
					{
						"name":"102628189 uncharacterized protein LOC102628189\tK23314 WRAP53; telomerase Cajal body protein 1"
					},
					{
						"name":"102609202 uncharacterized protein LOC102609202\tK24752 WDR70; WD repeat-containing protein 70"
					},
					{
						"name":"102622839 DNA damage-binding protein cmr1\tK24755 WDR76; WD repeat-containing protein 76"
					},
					{
						"name":"102620840 uncharacterized protein LOC102620840\tK28434 HMCES; abasic site processing protein HMCES"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"TLS (translesion DNA synthesis) factors",
			"children":[
			{
				"name":"Y-family DNA polymerases",
				"children":[
				{
					"name":"102631204 DNA polymerase eta isoform X4\tK03509 POLH; DNA polymerase eta [EC:2.7.7.7]"
				},
				{
					"name":"102631401 DNA polymerase kappa\tK03511 POLK; DNA polymerase kappa [EC:2.7.7.7]"
				},
				{
					"name":"102626428 DNA repair protein REV1 isoform X1\tK03515 REV1; DNA repair protein REV1 [EC:2.7.7.-]"
				}
				]
			},
			{
				"name":"B-family DNA polymerases",
				"children":[
				{
					"name":"102622531 LOW QUALITY PROTEIN: DNA polymerase zeta catalytic subunit\tK02350 REV3L; DNA polymerase zeta [EC:2.7.7.7]"
				}
				]
			},
			{
				"name":"A-family DNA polymerase"
			},
			{
				"name":"Rad6 epistasis group",
				"children":[
				{
					"name":"102607558 ubiquitin-conjugating enzyme E2 2\tK10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]"
				},
				{
					"name":"102610592 ubiquitin-conjugating enzyme E2 2-like\tK10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]"
				},
				{
					"name":"102610902 ubiquitin-conjugating enzyme E2 2-like\tK10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]"
				},
				{
					"name":"102624425 uncharacterized protein LOC102624425\tK10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]"
				},
				{
					"name":"102628134 ubiquitin-conjugating enzyme E2 2\tK10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]"
				},
				{
					"name":"102614855 DNA repair protein RAD5A\tK15505 RAD5; DNA repair protein RAD5 [EC:5.6.2.-]"
				},
				{
					"name":"102608925 putative SWI\/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3-like 1\tK15711 SMARCA3; SWI\/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A3 [EC:5.6.2. 2.3.2.27]"
				},
				{
					"name":"102577979 UEV; ubiquitin-conjugating enzyme variant\tK10704 UBE2V; ubiquitin-conjugating enzyme E2 variant"
				},
				{
					"name":"102626070 ubiquitin-conjugating enzyme E2 variant 1B-like\tK10704 UBE2V; ubiquitin-conjugating enzyme E2 variant"
				},
				{
					"name":"102577935 UBC13; ubiquitin-conjugating enzyme 13\tK10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]"
				},
				{
					"name":"102609816 ubiquitin-conjugating enzyme E2 36\tK10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]"
				}
				]
			},
			{
				"name":"Other TLS factors",
				"children":[
				{
					"name":"102627400 proliferating cell nuclear antigen\tK04802 PCNA; proliferating cell nuclear antigen"
				}
				]
			}
			]
		},
		{
			"name":"Check point factors",
			"children":[
			{
				"name":"Rad9-Hus1-Rad1 complex",
				"children":[
				{
					"name":"102611453 uncharacterized protein LOC102611453 isoform X1\tK10994 RAD9A; cell cycle checkpoint control protein RAD9A [EC:3.1.11.2]"
				},
				{
					"name":"102608019 uncharacterized protein LOC102608019\tK10903 HUS1; HUS1 checkpoint protein"
				},
				{
					"name":"102612729 uncharacterized protein LOC102612729\tK10903 HUS1; HUS1 checkpoint protein"
				},
				{
					"name":"102614578 uncharacterized protein LOC102614578\tK10903 HUS1; HUS1 checkpoint protein"
				},
				{
					"name":"112495979 uncharacterized protein LOC112495979\tK10903 HUS1; HUS1 checkpoint protein"
				},
				{
					"name":"127903799 LOW QUALITY PROTEIN: uncharacterized protein LOC127903799\tK10903 HUS1; HUS1 checkpoint protein"
				},
				{
					"name":"102608653 uncharacterized protein LOC102608653 isoform X1\tK02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]"
				}
				]
			},
			{
				"name":"HRAD17(Rad24)-RFC complex",
				"children":[
				{
					"name":"102630797 cell cycle checkpoint protein RAD17 isoform X1\tK06662 HRAD17; cell cycle checkpoint protein"
				},
				{
					"name":"102616275 replication factor C subunit 4 isoform X1\tK10755 RFC2_4; replication factor C subunit 2\/4"
				},
				{
					"name":"102617383 replication factor C subunit 2\tK10755 RFC2_4; replication factor C subunit 2\/4"
				},
				{
					"name":"102609520 uncharacterized protein LOC102609520\tK10756 RFC3_5; replication factor C subunit 3\/5"
				},
				{
					"name":"102612743 replication factor C subunit 3\tK10756 RFC3_5; replication factor C subunit 3\/5"
				},
				{
					"name":"102615422 replication factor C subunit 3\tK10756 RFC3_5; replication factor C subunit 3\/5"
				},
				{
					"name":"102625196 replication factor C subunit 3-like\tK10756 RFC3_5; replication factor C subunit 3\/5"
				}
				]
			},
			{
				"name":"Rad17-Mec3-Ddc1 complex",
				"children":[
				{
					"name":"102608653 uncharacterized protein LOC102608653 isoform X1\tK02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]"
				}
				]
			},
			{
				"name":"FPC (fork protection complex)",
				"children":[
				{
					"name":"102618757 uncharacterized protein LOC102618757 isoform X1\tK10997 TIMELESS; replication fork protection complex subunit TIMELESS\/Tof1\/Swi1"
				},
				{
					"name":"102621455 uncharacterized protein LOC102621455\tK10998 TIPIN; replication fork protection complex subunit TIPIN\/Csm3\/Swi3"
				}
				]
			},
			{
				"name":"Triple T complex",
				"children":[
				{
					"name":"102620559 uncharacterized protein LOC102620559\tK11137 TELO2; telomere length regulation protein"
				},
				{
					"name":"102623431 uncharacterized protein LOC102623431\tK20403 TTI1; TELO2-interacting protein 1"
				},
				{
					"name":"102619829 uncharacterized protein At2g39910 isoform X1\tK23115 TTI2; TELO2-interacting protein 2"
				}
				]
			},
			{
				"name":"BAG6-UBL4A-GET4 complex",
				"children":[
				{
					"name":"102615017 ubiquitin-like domain-containing protein CIP73 isoform X3\tK23390 BAG6; large proline-rich protein BAG6"
				},
				{
					"name":"102623665 protein GET4\tK23387 GET4; golgi to ER traffic protein 4"
				}
				]
			},
			{
				"name":"SOSS complex",
				"children":[
				{
					"name":"102611444 uncharacterized protein LOC102611444\tK13140 INTS3; integrator complex subunit 3 (SOSS complex subunit A)"
				},
				{
					"name":"102619405 uncharacterized protein LOC102619405\tK28889 NABP; SOSS complex subunit B"
				}
				]
			},
			{
				"name":"Other check point factors",
				"children":[
				{
					"name":"102612093 serine\/threonine-protein kinase ATR isoform X1\tK06640 ATR; serine\/threonine-protein kinase ATR [EC:2.7.11.1]"
				},
				{
					"name":"102620162 serine\/threonine-protein kinase ATM isoform X5\tK04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]"
				},
				{
					"name":"102608475 14-3-3-like protein D isoform X1\tK06630 YWHAE; 14-3-3 protein epsilon"
				},
				{
					"name":"102613414 14-3-3-like protein D\tK06630 YWHAE; 14-3-3 protein epsilon"
				},
				{
					"name":"102617582 14-3-3-like protein A\tK06630 YWHAE; 14-3-3 protein epsilon"
				},
				{
					"name":"102622535 14-3-3-like protein isoform X1\tK06630 YWHAE; 14-3-3 protein epsilon"
				},
				{
					"name":"102623806 14-3-3 protein 6\tK06630 YWHAE; 14-3-3 protein epsilon"
				},
				{
					"name":"102628987 14-3-3 protein 7\tK06630 YWHAE; 14-3-3 protein epsilon"
				},
				{
					"name":"102630125 14-3-3-like protein B\tK06630 YWHAE; 14-3-3 protein epsilon"
				},
				{
					"name":"102630465 14-3-3-like protein GF14 iota isoform X3\tK06630 YWHAE; 14-3-3 protein epsilon"
				},
				{
					"name":"102630484 14-3-3-like protein GF14 kappa isoform X1\tK06630 YWHAE; 14-3-3 protein epsilon"
				},
				{
					"name":"102614168 wee1-like protein kinase isoform X1\tK06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]"
				},
				{
					"name":"102618575 uncharacterized protein LOC102618575 isoform X1\tK20780 MDC1; mediator of DNA damage checkpoint protein 1"
				},
				{
					"name":"102608053 serine\/threonine-protein kinase Nek5\tK08857 NEK1_4_5; serine\/threonine-protein kinase Nek1\/4\/5 [EC:2.7.11.1]"
				},
				{
					"name":"102613123 serine\/threonine-protein kinase Nek6-like isoform X2\tK08857 NEK1_4_5; serine\/threonine-protein kinase Nek1\/4\/5 [EC:2.7.11.1]"
				},
				{
					"name":"102613697 serine\/threonine-protein kinase Nek6\tK08857 NEK1_4_5; serine\/threonine-protein kinase Nek1\/4\/5 [EC:2.7.11.1]"
				},
				{
					"name":"102613929 serine\/threonine-protein kinase Nek1-like\tK08857 NEK1_4_5; serine\/threonine-protein kinase Nek1\/4\/5 [EC:2.7.11.1]"
				},
				{
					"name":"102625540 serine\/threonine-protein kinase Nek2\tK08857 NEK1_4_5; serine\/threonine-protein kinase Nek1\/4\/5 [EC:2.7.11.1]"
				},
				{
					"name":"102614742 uncharacterized protein LOC102614742 isoform X1\tK22422 DONSON; protein downstream neighbor of Son"
				},
				{
					"name":"102616626 protein SUPPRESSOR OF K(+) TRANSPORT GROWTH DEFECT 1\tK12196 VPS4; vacuolar protein-sorting-associated protein 4"
				},
				{
					"name":"102619656 uncharacterized protein LOC102619656\tK25059 SDE2; replication stress response regulator SDE2"
				},
				{
					"name":"127901093 uncharacterized protein LOC127901093\tK25059 SDE2; replication stress response regulator SDE2"
				},
				{
					"name":"102610888 protein DECREASED SIZE EXCLUSION LIMIT 1 isoform X1\tK24770 DSE1; protein decreased size exclusion limit 1"
				}
				]
			}
			]
		},
		{
			"name":"Other factors with a suspected DNA repair function",
			"children":[
			{
				"name":"DNA polymerases",
				"children":[
				{
					"name":"102618799 helicase and polymerase-containing protein TEBICHI\tK02349 POLQ; DNA polymerase theta [EC:2.7.7.7]"
				},
				{
					"name":"102615838 uncharacterized protein LOC102615838\tK02331 POL5; DNA polymerase phi [EC:2.7.7.7]"
				},
				{
					"name":"102625684 uncharacterized protein LOC102625684\tK22761 PRIMPOL; DNA-directed primase\/polymerase protein [EC:2.7.7.102 2.7.7.7]"
				}
				]
			},
			{
				"name":"Nucleases",
				"children":[
				{
					"name":"102608159 uncharacterized protein LOC102608159 isoform X1\tK15340 DCLRE1A; DNA cross-link repair 1A protein"
				},
				{
					"name":"102610837 DNA cross-link repair protein SNM1\tK15340 DCLRE1A; DNA cross-link repair 1A protein"
				},
				{
					"name":"102626587 uncharacterized protein LOC102626587\tK15340 DCLRE1A; DNA cross-link repair 1A protein"
				},
				{
					"name":"102617172 uncharacterized protein LOC102617172 isoform X1\tK15341 DCLRE1B; DNA cross-link repair 1B protein [EC:3.1.-.-]"
				},
				{
					"name":"102618279 exonuclease V, chloroplastic\tK17815 EXO5; exonuclease V [EC:3.1.-.-]"
				},
				{
					"name":"102628555 uncharacterized protein LOC102628555 isoform X1\tK21813 ENDOV; endonuclease V [EC:3.1.26.-]"
				},
				{
					"name":"102611082 uncharacterized protein LOC102611082 isoform X1\tK25861 ZRANB3; DNA annealing helicase and endonuclease ZRANB3 [EC:5.6.2.- 3.1.-.-]"
				},
				{
					"name":"102621066 endonuclease 2\tK05986 NUCS; nuclease S1 [EC:3.1.30.1]"
				},
				{
					"name":"102622496 endonuclease 1\tK05986 NUCS; nuclease S1 [EC:3.1.30.1]"
				},
				{
					"name":"102622801 endonuclease 4 isoform X2\tK05986 NUCS; nuclease S1 [EC:3.1.30.1]"
				}
				]
			},
			{
				"name":"Helicases",
				"children":[
				{
					"name":"102616483 switch 2 isoform X2\tK20098 ERCC6L2; DNA excision repair protein ERCC-6-like 2 [EC:5.6.2.-]"
				}
				]
			},
			{
				"name":"PSO4 complex",
				"children":[
				{
					"name":"102630495 pre-mRNA-processing factor 19 homolog 2\tK10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]"
				},
				{
					"name":"102611813 cell division cycle 5-like protein\tK12860 CDC5L; pre-mRNA-splicing factor CDC5\/CEF1"
				},
				{
					"name":"102608089 pre-mRNA-splicing factor SPF27 homolog isoform X1\tK12861 BCAS2; pre-mRNA-splicing factor SPF27"
				},
				{
					"name":"102611423 protein pleiotropic regulatory locus 1\tK12862 PLRG1; pleiotropic regulator 1"
				}
				]
			},
			{
				"name":"Modulation of nucleotide pools",
				"children":[
				{
					"name":"102616605 nudix hydrolase 1\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]"
				},
				{
					"name":"102622151 deoxyuridine 5'-triphosphate nucleotidohydrolase-like isoform X1\tK01520 dut; dUTP diphosphatase [EC:3.6.1.23]"
				},
				{
					"name":"102629555 deoxyuridine 5'-triphosphate nucleotidohydrolase\tK01520 dut; dUTP diphosphatase [EC:3.6.1.23]"
				},
				{
					"name":"102611797 ribonucleoside-diphosphate reductase large subunit-like\tK10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]"
				},
				{
					"name":"102612388 ribonucleoside-diphosphate reductase large subunit isoform X1\tK10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]"
				},
				{
					"name":"102621651 ribonucleoside-diphosphate reductase large subunit-like isoform X1\tK10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]"
				},
				{
					"name":"102614082 ribonucleoside-diphosphate reductase small chain-like\tK10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]"
				},
				{
					"name":"102624257 ribonucleoside-diphosphate reductase small chain A\tK10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]"
				},
				{
					"name":"102625479 ribonucleoside-diphosphate reductase small chain\tK10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic type",
		"children":[
		{
			"name":"SSBR (single strand breaks repair)",
			"children":[
			{
				"name":"Direct repair",
				"children":[
				{
					"name":"102607644 deoxyribodipyrimidine photo-lyase isoform X1\tK01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]"
				}
				]
			},
			{
				"name":"BER (base exicision repair)",
				"children":[
				{
					"name":"DNA glycosylases",
					"children":[
					{
						"name":"102619856 uracil-DNA glycosylase, mitochondrial isoform X1\tK03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]"
					},
					{
						"name":"102613060 alkylbase DNA glycosidase-like protein mag2 isoform X1\tK01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]"
					},
					{
						"name":"102629620 DNA-3-methyladenine glycosylase 1\tK01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]"
					},
					{
						"name":"102620793 DNA-3-methyladenine glycosylase isoform X1\tK03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]"
					},
					{
						"name":"102622215 adenine DNA glycosylase\tK03575 mutY; A\/G-specific adenine glycosylase [EC:3.2.2.31]"
					},
					{
						"name":"102607933 uncharacterized protein LOC102607933 isoform X2\tK01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]"
					},
					{
						"name":"102614205 uncharacterized protein LOC102614205\tK01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]"
					},
					{
						"name":"102621461 uncharacterized protein LOC102621461\tK01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]"
					},
					{
						"name":"102623818 LOW QUALITY PROTEIN: uncharacterized protein LOC102623818\tK01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]"
					},
					{
						"name":"102627575 uncharacterized protein LOC102627575 isoform X1\tK01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]"
					},
					{
						"name":"102621076 formamidopyrimidine-DNA glycosylase isoform X1\tK10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]"
					},
					{
						"name":"102616863 endonuclease III homolog 1, chloroplastic-like isoform X1\tK10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]"
					},
					{
						"name":"102617365 endonuclease III homolog 1, chloroplastic-like isoform X1\tK10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]"
					},
					{
						"name":"102627550 putative DNA glycosylase At3g47830 isoform X1\tK10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]"
					}
					]
				},
				{
					"name":"AP endonucleases",
					"children":[
					{
						"name":"102617923 DNA-(apurinic or apyrimidinic site) endonuclease, chloroplastic isoform X1\tK01142 xthA; exodeoxyribonuclease III [EC:3.1.11.2]"
					}
					]
				},
				{
					"name":"RecJ"
				},
				{
					"name":"DNA ligase"
				},
				{
					"name":"DNA polymerase I",
					"children":[
					{
						"name":"102617268 DNA polymerase I B, chloroplastic\/mitochondrial isoform X1\tK02335 polA; DNA polymerase I [EC:2.7.7.7]"
					}
					]
				}
				]
			},
			{
				"name":"NER (nucleotide excision repair)",
				"children":[
				{
					"name":"GGR (global genome repair) factors",
					"children":[
					{
						"name":"102617268 DNA polymerase I B, chloroplastic\/mitochondrial isoform X1\tK02335 polA; DNA polymerase I [EC:2.7.7.7]"
					}
					]
				},
				{
					"name":"TCR (transcription coupled repair) factors",
					"children":[
					{
						"name":"DNA-directed RNA polymerase complex (RNAP)",
						"children":[
						{
							"name":"4271235 rpoB; RNA polymerase beta subunit\tK03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]"
						},
						{
							"name":"4271233 rpoC2; RNA polymerase beta'' subunit\tK03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]"
						},
						{
							"name":"4271234 rpoC1; RNA polymerase beta' subunit\tK03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]"
						},
						{
							"name":"4271184 rpoA; RNA polymerase alpha subunit\tK03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]"
						}
						]
					},
					{
						"name":"TRCF (transcription-repair coupling factor)"
					}
					]
				}
				]
			},
			{
				"name":"MMR (mismatch excision repair)",
				"children":[
				{
					"name":"Mismatch and loop recognition factors",
					"children":[
					{
						"name":"102631102 uncharacterized protein LOC102631102\tK07456 mutS2; DNA mismatch repair protein MutS2"
					}
					]
				},
				{
					"name":"Molecular matchmaker"
				},
				{
					"name":"Strand discrimination factor"
				},
				{
					"name":"DNA exonucleases"
				},
				{
					"name":"DNA polymerase III holoenzyme"
				},
				{
					"name":"DNA ligase"
				},
				{
					"name":"Other MMR factors",
					"children":[
					{
						"name":"102620340 single-stranded DNA-binding protein, mitochondrial\tK03111 ssb; single-strand DNA-binding protein"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"DSBR (double strand breaks repair)",
			"children":[
			{
				"name":"HR (homologous recombination)",
				"children":[
				{
					"name":"RecBC pathway proteins",
					"children":[
					{
						"name":"102614724 DNA repair protein RecA homolog 3, mitochondrial isoform X1\tK03553 recA; recombination protein RecA"
					},
					{
						"name":"102626696 DNA repair protein RecA homolog 1, chloroplastic isoform X2\tK03553 recA; recombination protein RecA"
					}
					]
				},
				{
					"name":"RecFOR pathway proteins",
					"children":[
					{
						"name":"102614724 DNA repair protein RecA homolog 3, mitochondrial isoform X1\tK03553 recA; recombination protein RecA"
					},
					{
						"name":"102626696 DNA repair protein RecA homolog 1, chloroplastic isoform X2\tK03553 recA; recombination protein RecA"
					},
					{
						"name":"102628276 uncharacterized protein LOC102628276\tK04485 radA; DNA repair protein RadA\/Sms"
					},
					{
						"name":"102606824 ATP-dependent DNA helicase homolog RECG, chloroplastic isoform X1\tK03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]"
					}
					]
				},
				{
					"name":"AddAB pathway proteins"
				},
				{
					"name":"Other HR factor"
				},
				{
					"name":"Archaeal homologous recombinant proteins"
				}
				]
			},
			{
				"name":"NHEJ (non-homologous end-joining)",
				"children":[
				{
					"name":"Two-component NHEJ DNA repair complex"
				},
				{
					"name":"SHIIR (short-homology-independent illegitimate recombination)",
					"children":[
					{
						"name":"Facilitator",
						"children":[
						{
							"name":"102623274 DNA gyrase subunit A, chloroplastic\/mitochondrial isoform X1\tK02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]"
						},
						{
							"name":"102614049 DNA gyrase subunit B, chloroplastic\/mitochondrial-like isoform X1\tK02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]"
						}
						]
					},
					{
						"name":"Supressor"
					}
					]
				},
				{
					"name":"SHDIR (short-homology-dependent illegitimate recombination)",
					"children":[
					{
						"name":"RecET pathway"
					},
					{
						"name":"Facilitator"
					},
					{
						"name":"Supressor",
						"children":[
						{
							"name":"102613336 uncharacterized protein LOC102613336\tK03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]"
						}
						]
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"TLS (translesion DNA synthesis) factors",
			"children":[
			{
				"name":"Y-family DNA polymerases"
			},
			{
				"name":"Other SOS response factors",
				"children":[
				{
					"name":"102614724 DNA repair protein RecA homolog 3, mitochondrial isoform X1\tK03553 recA; recombination protein RecA"
				},
				{
					"name":"102626696 DNA repair protein RecA homolog 1, chloroplastic isoform X2\tK03553 recA; recombination protein RecA"
				},
				{
					"name":"102620340 single-stranded DNA-binding protein, mitochondrial\tK03111 ssb; single-strand DNA-binding protein"
				}
				]
			}
			]
		},
		{
			"name":"Other factors with a suspected DNA repair function",
			"children":[
			{
				"name":"DNA polymerase"
			},
			{
				"name":"DNA helicases"
			},
			{
				"name":"Modulation of nucleotide pools",
				"children":[
				{
					"name":"102616605 nudix hydrolase 1\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]"
				},
				{
					"name":"102622151 deoxyuridine 5'-triphosphate nucleotidohydrolase-like isoform X1\tK01520 dut; dUTP diphosphatase [EC:3.6.1.23]"
				},
				{
					"name":"102629555 deoxyuridine 5'-triphosphate nucleotidohydrolase\tK01520 dut; dUTP diphosphatase [EC:3.6.1.23]"
				}
				]
			},
			{
				"name":"Others"
			}
			]
		}
		]
	}
	]
}