{
	"name":"cmos03032",
	"children":[
	{
		"name":"Eukaryotic type",
		"children":[
		{
			"name":"DNA Replication Initiation Factors",
			"children":[
			{
				"name":"pre-RC (pre-replication complex)",
				"children":[
				{
					"name":"111432707 origin of replication complex subunit 1B-like isoform X1\tK02603 ORC1; origin recognition complex subunit 1"
				},
				{
					"name":"111454083 origin of replication complex subunit 2\tK02604 ORC2; origin recognition complex subunit 2"
				},
				{
					"name":"111459306 origin of replication complex subunit 3 isoform X1\tK02605 ORC3; origin recognition complex subunit 3"
				},
				{
					"name":"111458176 origin of replication complex subunit 4 isoform X1\tK02606 ORC4; origin recognition complex subunit 4"
				},
				{
					"name":"111460349 origin of replication complex subunit 5\tK02607 ORC5; origin recognition complex subunit 5"
				},
				{
					"name":"111450377 origin of replication complex subunit 6\tK02608 ORC6; origin recognition complex subunit 6"
				},
				{
					"name":"111456741 CDT1-like protein a, chloroplastic\tK10727 CDT1; chromatin licensing and DNA replication factor 1"
				},
				{
					"name":"111464103 CDT1-like protein b\tK10727 CDT1; chromatin licensing and DNA replication factor 1"
				},
				{
					"name":"111448195 cell division control protein 6 homolog B-like\tK02213 CDC6; cell division control protein 6"
				},
				{
					"name":"111439083 DNA replication licensing factor MCM2-like isoform X1\tK02540 MCM2; DNA replication licensing factor MCM2 [EC:5.6.2.3]"
				},
				{
					"name":"111442009 DNA replication licensing factor MCM2-like isoform X1\tK02540 MCM2; DNA replication licensing factor MCM2 [EC:5.6.2.3]"
				},
				{
					"name":"111433891 DNA replication licensing factor MCM3 homolog 1\tK02541 MCM3; DNA replication licensing factor MCM3 [EC:5.6.2.3]"
				},
				{
					"name":"111432387 DNA replication licensing factor MCM4-like\tK02212 MCM4; DNA replication licensing factor MCM4 [EC:5.6.2.3]"
				},
				{
					"name":"111455061 DNA replication licensing factor MCM4-like\tK02212 MCM4; DNA replication licensing factor MCM4 [EC:5.6.2.3]"
				},
				{
					"name":"111444328 DNA replication licensing factor MCM5\tK02209 MCM5; DNA replication licensing factor MCM5 [EC:5.6.2.3]"
				},
				{
					"name":"111433657 DNA replication licensing factor MCM6 isoform X1\tK02542 MCM6; DNA replication licensing factor MCM6 [EC:5.6.2.3]"
				},
				{
					"name":"111456541 DNA replication licensing factor MCM7\tK02210 MCM7; DNA replication licensing factor MCM7 [EC:5.6.2.3]"
				},
				{
					"name":"111460664 DNA replication licensing factor MCM7-like\tK02210 MCM7; DNA replication licensing factor MCM7 [EC:5.6.2.3]"
				}
				]
			},
			{
				"name":"CDK (cyclin dependent kinase)",
				"children":[
				{
					"name":"111443312 putative cyclin-A3-1\tK06627 CCNA; cyclin-A"
				},
				{
					"name":"111443357 cyclin-A2-2-like\tK06627 CCNA; cyclin-A"
				},
				{
					"name":"111444914 cyclin-A1-1-like isoform X1\tK06627 CCNA; cyclin-A"
				},
				{
					"name":"111446012 cyclin-A2-2-like\tK06627 CCNA; cyclin-A"
				},
				{
					"name":"111446635 putative cyclin-A3-1\tK06627 CCNA; cyclin-A"
				},
				{
					"name":"111454209 cyclin-A2-1-like\tK06627 CCNA; cyclin-A"
				},
				{
					"name":"111454745 putative cyclin-A3-1\tK06627 CCNA; cyclin-A"
				},
				{
					"name":"111455110 G2\/mitotic-specific cyclin C13-1-like\tK06627 CCNA; cyclin-A"
				},
				{
					"name":"111456383 cyclin-A1-1-like\tK06627 CCNA; cyclin-A"
				},
				{
					"name":"111456432 cyclin-A2-3\tK06627 CCNA; cyclin-A"
				},
				{
					"name":"111460767 cyclin-A2-4-like\tK06627 CCNA; cyclin-A"
				},
				{
					"name":"111462596 putative cyclin-A3-1\tK06627 CCNA; cyclin-A"
				},
				{
					"name":"111449422 cell division control protein 2 homolog\tK02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]"
				},
				{
					"name":"111458853 cell division control protein 2 homolog A\tK02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]"
				}
				]
			},
			{
				"name":"DDK (Dbf-4 dependent kinase)",
				"children":[
				{
					"name":"111439726 serine\/threonine-protein kinase RIM15-like isoform X1\tK02214 CDC7; cell division control protein 7 [EC:2.7.11.1]"
				},
				{
					"name":"111460633 uncharacterized protein LOC111460633\tK02214 CDC7; cell division control protein 7 [EC:2.7.11.1]"
				}
				]
			},
			{
				"name":"GINS complex",
				"children":[
				{
					"name":"111464174 probable DNA replication complex GINS protein PSF1\tK10732 GINS1; GINS complex subunit 1"
				},
				{
					"name":"111432452 DNA replication complex GINS protein PSF2 isoform X1\tK10733 GINS2; GINS complex subunit 2"
				},
				{
					"name":"111462725 DNA replication complex GINS protein PSF3-like\tK10734 GINS3; GINS complex subunit 3"
				},
				{
					"name":"111431969 DNA replication complex GINS protein SLD5\tK10735 GINS4; GINS complex subunit 4"
				}
				]
			},
			{
				"name":"Other initiation factors",
				"children":[
				{
					"name":"111443414 DNA topoisomerase 2-binding protein 1 isoform X1\tK10728 TOPBP1; topoisomerase (DNA) II binding protein 1"
				},
				{
					"name":"111455969 BRCT domain-containing protein At4g02110 isoform X1\tK10728 TOPBP1; topoisomerase (DNA) II binding protein 1"
				},
				{
					"name":"111449514 ATP-dependent DNA helicase Q-like 5 isoform X1\tK10730 RECQL4; ATP-dependent DNA helicase Q4 [EC:5.6.2.4]"
				},
				{
					"name":"111455794 cell division control protein 45 homolog\tK06628 CDC45; cell division control protein 45"
				},
				{
					"name":"111460658 cell division control protein 45 homolog\tK06628 CDC45; cell division control protein 45"
				},
				{
					"name":"111441466 probable DNA helicase MCM8 isoform X1\tK10737 MCM8; DNA helicase MCM8 [EC:5.6.2.4]"
				},
				{
					"name":"111455445 probable DNA helicase MCM9 isoform X1\tK10738 MCM9; DNA helicase MCM9 [EC:5.6.2.4]"
				},
				{
					"name":"111448185 protein MCM10 homolog\tK10736 MCM10; minichromosome maintenance protein 10"
				},
				{
					"name":"111445598 mini-chromosome maintenance complex-binding protein-like\tK28390 MCMBP; minichromosome maintenance complex-binding protein"
				},
				{
					"name":"111464610 mini-chromosome maintenance complex-binding protein-like isoform X1\tK28390 MCMBP; minichromosome maintenance complex-binding protein"
				}
				]
			}
			]
		},
		{
			"name":"DNA Replication Elongation Factors",
			"children":[
			{
				"name":"DNA polymerase alpha \/ primase complex",
				"children":[
				{
					"name":"111451682 DNA polymerase alpha catalytic subunit\tK02320 POLA1; DNA polymerase alpha subunit A [EC:2.7.7.7]"
				},
				{
					"name":"111449321 DNA polymerase alpha subunit B\tK02321 POLA2; DNA polymerase alpha subunit B"
				},
				{
					"name":"111432676 DNA primase small subunit\tK02684 PRI1; DNA primase small subunit [EC:2.7.7.102]"
				},
				{
					"name":"111460608 probable DNA primase large subunit isoform X1\tK02685 PRI2; DNA primase large subunit"
				}
				]
			},
			{
				"name":"DNA polymerase epsilon complex",
				"children":[
				{
					"name":"111459170 DNA polymerase epsilon catalytic subunit A-like\tK02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]"
				},
				{
					"name":"111452793 DNA polymerase epsilon subunit B\tK02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]"
				},
				{
					"name":"111459853 DNA polymerase epsilon subunit 3\tK02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]"
				}
				]
			},
			{
				"name":"DNA polymerase delta complex",
				"children":[
				{
					"name":"111463461 DNA polymerase delta catalytic subunit\tK02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]"
				},
				{
					"name":"111441443 DNA polymerase delta small subunit\tK02328 POLD2; DNA polymerase delta subunit 2"
				},
				{
					"name":"111446774 uncharacterized protein LOC111446774\tK03504 POLD3; DNA polymerase delta subunit 3"
				},
				{
					"name":"111459143 uncharacterized protein LOC111459143\tK03505 POLD4; DNA polymerase delta subunit 4"
				}
				]
			},
			{
				"name":"DNA polymerase gamma complex (mitochondrial)"
			},
			{
				"name":"RPA (replication protein A)",
				"children":[
				{
					"name":"111431058 replication protein A 70 kDa DNA-binding subunit A-like\tK07466 RFA1; replication factor A1"
				},
				{
					"name":"111440985 replication protein A 70 kDa DNA-binding subunit B-like\tK07466 RFA1; replication factor A1"
				},
				{
					"name":"111448678 replication protein A 70 kDa DNA-binding subunit A\tK07466 RFA1; replication factor A1"
				},
				{
					"name":"111450710 replication protein A 70 kDa DNA-binding subunit A\tK07466 RFA1; replication factor A1"
				},
				{
					"name":"111430133 replication protein A 32 kDa subunit B-like isoform X1\tK10739 RFA2; replication factor A2"
				},
				{
					"name":"111436658 replication protein A 32 kDa subunit B-like\tK10739 RFA2; replication factor A2"
				},
				{
					"name":"111443128 replication protein A 32 kDa subunit A-like\tK10739 RFA2; replication factor A2"
				},
				{
					"name":"111442076 replication protein A 14 kDa subunit B-like\tK10740 RPA3; replication factor A3"
				},
				{
					"name":"111447925 replication protein A 14 kDa subunit B-like\tK10740 RPA3; replication factor A3"
				}
				]
			},
			{
				"name":"RFC (replication factor C)",
				"children":[
				{
					"name":"111459280 replication factor C subunit 1 isoform X1\tK10754 RFC1; replication factor C subunit 1"
				},
				{
					"name":"111431154 replication factor C subunit 2\tK10755 RFC2_4; replication factor C subunit 2\/4"
				},
				{
					"name":"111445849 replication factor C subunit 4\tK10755 RFC2_4; replication factor C subunit 2\/4"
				},
				{
					"name":"111445586 replication factor C subunit 3-like\tK10756 RFC3_5; replication factor C subunit 3\/5"
				},
				{
					"name":"111450354 replication factor C subunit 3-like\tK10756 RFC3_5; replication factor C subunit 3\/5"
				},
				{
					"name":"111453820 replication factor C subunit 3 isoform X1\tK10756 RFC3_5; replication factor C subunit 3\/5"
				},
				{
					"name":"111458994 replication factor C subunit 3-like\tK10756 RFC3_5; replication factor C subunit 3\/5"
				},
				{
					"name":"111463451 uncharacterized protein LOC111463451\tK10756 RFC3_5; replication factor C subunit 3\/5"
				}
				]
			},
			{
				"name":"RNase H",
				"children":[
				{
					"name":"111457459 ribonuclease H2 subunit A\tK10743 RNASEH2A; ribonuclease H2 subunit A [EC:3.1.26.4]"
				},
				{
					"name":"111462943 ribonuclease H2 subunit B\tK10744 RNASEH2B; ribonuclease H2 subunit B"
				},
				{
					"name":"111434094 uncharacterized protein C12B10.15c\tK10745 RNASEH2C; ribonuclease H2 subunit C"
				}
				]
			},
			{
				"name":"Other elongation factors",
				"children":[
				{
					"name":"111447316 proliferating cell nuclear antigen-like\tK04802 PCNA; proliferating cell nuclear antigen"
				},
				{
					"name":"111449114 proliferating cell nuclear antigen\tK04802 PCNA; proliferating cell nuclear antigen"
				},
				{
					"name":"111451602 proliferating cell nuclear antigen-like\tK04802 PCNA; proliferating cell nuclear antigen"
				},
				{
					"name":"111432188 DNA replication ATP-dependent helicase\/nuclease DNA2 isoform X1\tK10742 DNA2; DNA replication ATP-dependent helicase\/nuclease Dna2 [EC:5.6.2.3 3.1.-.-]"
				},
				{
					"name":"111437876 flap endonuclease 1 isoform X1\tK04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]"
				},
				{
					"name":"111431511 exonuclease 1\tK10746 EXO1; exonuclease 1 [EC:3.1.-.-]"
				},
				{
					"name":"111456917 exonuclease 1 isoform X1\tK10746 EXO1; exonuclease 1 [EC:3.1.-.-]"
				},
				{
					"name":"111430052 DNA annealing helicase and endonuclease ZRANB3 isoform X1\tK25861 ZRANB3; DNA annealing helicase and endonuclease ZRANB3 [EC:5.6.2.- 3.1.-.-]"
				},
				{
					"name":"111448471 DNA ligase 1\tK10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]"
				},
				{
					"name":"111446318 uncharacterized protein LOC111446318 isoform X1\tK26118 ATAD5; ATPase family AAA domain-containing protein 5"
				}
				]
			}
			]
		},
		{
			"name":"DNA Replication Termination Factors",
			"children":[
			{
				"name":"DNA methylation enzymes",
				"children":[
				{
					"name":"111436142 DNA (cytosine-5)-methyltransferase CMT3-like\tK00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]"
				},
				{
					"name":"111436438 DNA (cytosine-5)-methyltransferase 1B-like isoform X1\tK00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]"
				},
				{
					"name":"111452488 DNA (cytosine-5)-methyltransferase CMT2 isoform X1\tK00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]"
				},
				{
					"name":"111461317 DNA (cytosine-5)-methyltransferase CMT3-like isoform X1\tK00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]"
				},
				{
					"name":"111444380 uncharacterized protein LOC111444380\tK17398 DNMT3A; DNA (cytosine-5)-methyltransferase 3A [EC:2.1.1.37]"
				},
				{
					"name":"111450395 uncharacterized protein LOC111450395\tK17398 DNMT3A; DNA (cytosine-5)-methyltransferase 3A [EC:2.1.1.37]"
				}
				]
			},
			{
				"name":"Prevention of re-replication factors",
				"children":[
				{
					"name":"111432319 G2\/mitotic-specific cyclin S13-7-like\tK21777 CCNB; G2\/mitotic-specific cyclin-B, other"
				},
				{
					"name":"111432355 G2\/mitotic-specific cyclin S13-7-like\tK21777 CCNB; G2\/mitotic-specific cyclin-B, other"
				},
				{
					"name":"111432356 G2\/mitotic-specific cyclin S13-7-like\tK21777 CCNB; G2\/mitotic-specific cyclin-B, other"
				},
				{
					"name":"111433539 G2\/mitotic-specific cyclin-2-like\tK21777 CCNB; G2\/mitotic-specific cyclin-B, other"
				},
				{
					"name":"111443270 cyclin-B2-3-like isoform X1\tK21777 CCNB; G2\/mitotic-specific cyclin-B, other"
				},
				{
					"name":"111445780 LOW QUALITY PROTEIN: G2\/mitotic-specific cyclin-2-like\tK21777 CCNB; G2\/mitotic-specific cyclin-B, other"
				},
				{
					"name":"111447678 cyclin-SDS-like\tK21777 CCNB; G2\/mitotic-specific cyclin-B, other"
				},
				{
					"name":"111447707 cyclin-SDS-like\tK21777 CCNB; G2\/mitotic-specific cyclin-B, other"
				},
				{
					"name":"111453079 G2\/mitotic-specific cyclin-2-like isoform X1\tK21777 CCNB; G2\/mitotic-specific cyclin-B, other"
				},
				{
					"name":"111455459 putative cyclin-B3-1 isoform X1\tK21777 CCNB; G2\/mitotic-specific cyclin-B, other"
				},
				{
					"name":"111459264 cyclin-B1-4-like\tK21777 CCNB; G2\/mitotic-specific cyclin-B, other"
				}
				]
			},
			{
				"name":"Telomere proteins",
				"children":[
				{
					"name":"Shelterin complex",
					"children":[
					{
						"name":"111448860 uncharacterized protein LOC111448860 isoform X1\tK11111 TERF2; telomeric repeat-binding factor 2"
					},
					{
						"name":"111451133 uncharacterized protein LOC111451133\tK11111 TERF2; telomeric repeat-binding factor 2"
					}
					]
				},
				{
					"name":"TERB1-TERB2-MAJIN complex"
				},
				{
					"name":"CST complex (animals)",
					"children":[
					{
						"name":"111463780 LOW QUALITY PROTEIN: CST complex subunit STN1\tK23312 STN1; CST complex subunit STN1"
					},
					{
						"name":"111444067 CST complex subunit TEN1\tK23313 TEN1; CST complex subunit TEN1"
					}
					]
				},
				{
					"name":"CST complex (yeast)"
				},
				{
					"name":"RIF proteins"
				},
				{
					"name":"SIR proteins"
				}
				]
			},
			{
				"name":"Telomerase complex (animals)",
				"children":[
				{
					"name":"111442424 telomerase reverse transcriptase isoform X1\tK11126 TERT; telomerase reverse transcriptase [EC:2.7.7.49]"
				},
				{
					"name":"Dyskerin complex",
					"children":[
					{
						"name":"111432388 putative H\/ACA ribonucleoprotein complex subunit 1-like protein 1\tK11128 GAR1; H\/ACA ribonucleoprotein complex subunit 1"
					},
					{
						"name":"111453623 putative H\/ACA ribonucleoprotein complex subunit 1-like protein 1\tK11128 GAR1; H\/ACA ribonucleoprotein complex subunit 1"
					},
					{
						"name":"111431634 H\/ACA ribonucleoprotein complex subunit 2-like protein\tK11129 NHP2; H\/ACA ribonucleoprotein complex subunit 2"
					},
					{
						"name":"111457314 H\/ACA ribonucleoprotein complex subunit 2-like protein\tK11129 NHP2; H\/ACA ribonucleoprotein complex subunit 2"
					},
					{
						"name":"111437463 H\/ACA ribonucleoprotein complex subunit 3-like protein\tK11130 NOP10; H\/ACA ribonucleoprotein complex subunit 3"
					},
					{
						"name":"111464097 H\/ACA ribonucleoprotein complex subunit 3-like protein\tK11130 NOP10; H\/ACA ribonucleoprotein complex subunit 3"
					},
					{
						"name":"111441884 H\/ACA ribonucleoprotein complex subunit 4-like\tK11131 DKC1; H\/ACA ribonucleoprotein complex subunit 4 [EC:5.4.99.-]"
					},
					{
						"name":"111446978 H\/ACA ribonucleoprotein complex subunit 4-like\tK11131 DKC1; H\/ACA ribonucleoprotein complex subunit 4 [EC:5.4.99.-]"
					}
					]
				}
				]
			},
			{
				"name":"Telomerase complex (fungi)",
				"children":[
				{
					"name":"111442424 telomerase reverse transcriptase isoform X1\tK11126 TERT; telomerase reverse transcriptase [EC:2.7.7.49]"
				},
				{
					"name":"Sm core complex",
					"children":[
					{
						"name":"111433057 small nuclear ribonucleoprotein-associated protein B'-like\tK11086 SNRPB; small nuclear ribonucleoprotein B and B'"
					},
					{
						"name":"111433699 small nuclear ribonucleoprotein-associated protein B'-like\tK11086 SNRPB; small nuclear ribonucleoprotein B and B'"
					},
					{
						"name":"111437383 small nuclear ribonucleoprotein SmD1b\tK11087 SNRPD1; small nuclear ribonucleoprotein D1"
					},
					{
						"name":"111451260 small nuclear ribonucleoprotein SmD1b-like\tK11087 SNRPD1; small nuclear ribonucleoprotein D1"
					},
					{
						"name":"111464127 small nuclear ribonucleoprotein SmD1b-like\tK11087 SNRPD1; small nuclear ribonucleoprotein D1"
					},
					{
						"name":"111435853 small nuclear ribonucleoprotein Sm D2-like\tK11096 SNRPD2; small nuclear ribonucleoprotein D2"
					},
					{
						"name":"111447757 small nuclear ribonucleoprotein Sm D2-like\tK11096 SNRPD2; small nuclear ribonucleoprotein D2"
					},
					{
						"name":"111443497 small nuclear ribonucleoprotein SmD3b-like\tK11088 SNRPD3; small nuclear ribonucleoprotein D3"
					},
					{
						"name":"111446231 small nuclear ribonucleoprotein SmD3b-like isoform X1\tK11088 SNRPD3; small nuclear ribonucleoprotein D3"
					},
					{
						"name":"111429915 small nuclear ribonucleoprotein E-like isoform X1\tK11097 SNRPE; small nuclear ribonucleoprotein E"
					},
					{
						"name":"111435765 small nuclear ribonucleoprotein E-like\tK11097 SNRPE; small nuclear ribonucleoprotein E"
					},
					{
						"name":"111438400 small nuclear ribonucleoprotein E-like\tK11097 SNRPE; small nuclear ribonucleoprotein E"
					},
					{
						"name":"111454427 probable small nuclear ribonucleoprotein F\tK11098 SNRPF; small nuclear ribonucleoprotein F"
					},
					{
						"name":"111462396 probable small nuclear ribonucleoprotein F\tK11098 SNRPF; small nuclear ribonucleoprotein F"
					},
					{
						"name":"111432957 probable small nuclear ribonucleoprotein G\tK11099 SNRPG; small nuclear ribonucleoprotein G"
					},
					{
						"name":"111463232 probable small nuclear ribonucleoprotein G\tK11099 SNRPG; small nuclear ribonucleoprotein G"
					}
					]
				}
				]
			},
			{
				"name":"ELG1-RFC complex",
				"children":[
				{
					"name":"111431154 replication factor C subunit 2\tK10755 RFC2_4; replication factor C subunit 2\/4"
				},
				{
					"name":"111445849 replication factor C subunit 4\tK10755 RFC2_4; replication factor C subunit 2\/4"
				},
				{
					"name":"111445586 replication factor C subunit 3-like\tK10756 RFC3_5; replication factor C subunit 3\/5"
				},
				{
					"name":"111450354 replication factor C subunit 3-like\tK10756 RFC3_5; replication factor C subunit 3\/5"
				},
				{
					"name":"111453820 replication factor C subunit 3 isoform X1\tK10756 RFC3_5; replication factor C subunit 3\/5"
				},
				{
					"name":"111458994 replication factor C subunit 3-like\tK10756 RFC3_5; replication factor C subunit 3\/5"
				},
				{
					"name":"111463451 uncharacterized protein LOC111463451\tK10756 RFC3_5; replication factor C subunit 3\/5"
				}
				]
			},
			{
				"name":"MRN complex",
				"children":[
				{
					"name":"111442996 double-strand break repair protein MRE11 isoform X1\tK10865 MRE11; double-strand break repair protein MRE11"
				},
				{
					"name":"111432029 DNA repair protein RAD50\tK10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]"
				},
				{
					"name":"111452863 nijmegen breakage syndrome 1 protein\tK10867 NBN; nibrin"
				}
				]
			},
			{
				"name":"Other termination factors",
				"children":[
				{
					"name":"111435229 serine\/threonine-protein kinase ATM isoform X1\tK04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]"
				},
				{
					"name":"111444411 ATP-dependent DNA helicase Q-like SIM\tK10900 WRN; werner syndrome ATP-dependent helicase [EC:5.6.2.4]"
				},
				{
					"name":"111430623 ATP-dependent DNA helicase Q-like 4A\tK10901 BLM; bloom syndrome protein [EC:5.6.2.4]"
				},
				{
					"name":"111444040 ATP-dependent DNA helicase Q-like 3 isoform X1\tK10901 BLM; bloom syndrome protein [EC:5.6.2.4]"
				},
				{
					"name":"111459549 DNA repair endonuclease UVH1\tK10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]"
				},
				{
					"name":"111463901 poly [ADP-ribose] polymerase 1\tK24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30]"
				},
				{
					"name":"111456153 poly [ADP-ribose] polymerase 2-like\tK28005 PARP2; poly [ADP-ribose] polymerase 2 [EC:2.4.2.30]"
				},
				{
					"name":"111460922 poly [ADP-ribose] polymerase 2-like\tK28005 PARP2; poly [ADP-ribose] polymerase 2 [EC:2.4.2.30]"
				},
				{
					"name":"111459773 PIN2\/TERF1-interacting telomerase inhibitor 1\tK11135 PINX1; Pin2-interacting protein X1"
				},
				{
					"name":"111456545 regulator of telomere elongation helicase 1 homolog isoform X1\tK11136 RTEL1; regulator of telomere elongation helicase 1 [EC:5.6.2.3]"
				},
				{
					"name":"111431405 telomere length regulation protein TEL2 homolog\tK11137 TELO2; telomere length regulation protein"
				},
				{
					"name":"111461361 uncharacterized protein LOC111461361\tK11138 RIF1; telomere-associated protein RIF1"
				},
				{
					"name":"111436059 transcription factor Pur-alpha 1-like\tK21772 PURA; transcriptional activator protein Pur-alpha"
				},
				{
					"name":"111461388 transcription factor Pur-alpha 1-like\tK21772 PURA; transcriptional activator protein Pur-alpha"
				},
				{
					"name":"111434065 telomerase Cajal body protein 1\tK23314 WRAP53; telomerase Cajal body protein 1"
				},
				{
					"name":"111436363 protein SDE2 homolog\tK25059 SDE2; replication stress response regulator SDE2"
				},
				{
					"name":"111461065 protein SDE2 homolog\tK25059 SDE2; replication stress response regulator SDE2"
				},
				{
					"name":"111430120 protein RTF2 homolog\tK25186 RTF2; replication termination factor 2"
				},
				{
					"name":"111440971 protein RTF2 homolog\tK25186 RTF2; replication termination factor 2"
				}
				]
			}
			]
		},
		{
			"name":"DNA Topoisomerases",
			"children":[
			{
				"name":"111438616 DNA topoisomerase 1 beta-like\tK03163 TOP1; DNA topoisomerase I [EC:5.6.2.1]"
			},
			{
				"name":"111446061 DNA topoisomerase 1 alpha-like\tK03163 TOP1; DNA topoisomerase I [EC:5.6.2.1]"
			},
			{
				"name":"111442005 DNA topoisomerase 2 isoform X1\tK03164 TOP2; DNA topoisomerase II [EC:5.6.2.2]"
			},
			{
				"name":"111441350 DNA topoisomerase 3-alpha isoform X1\tK03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]"
			},
			{
				"name":"111457562 DNA topoisomerase 3-beta isoform X1\tK03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]"
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic type",
		"children":[
		{
			"name":"DNA Replication Initiation Factors",
			"children":[
			{
				"name":"Initiation factors (bacterial)",
				"children":[
				{
					"name":"111431312 single-stranded DNA-binding protein, mitochondrial-like\tK03111 ssb; single-strand DNA-binding protein"
				}
				]
			},
			{
				"name":"Initiation factors (archaeal)"
			}
			]
		},
		{
			"name":"DNA Replication Elongation Factors",
			"children":[
			{
				"name":"Elongation factors (bacterial)",
				"children":[
				{
					"name":"DNA polymerase III holoenzyme"
				},
				{
					"name":"RNase H"
				},
				{
					"name":"Other elongation factors",
					"children":[
					{
						"name":"111438488 DNA polymerase I A, chloroplastic\/mitochondrial-like\tK02335 polA; DNA polymerase I [EC:2.7.7.7]"
					},
					{
						"name":"111447420 DNA polymerase I B, chloroplastic\/mitochondrial-like\tK02335 polA; DNA polymerase I [EC:2.7.7.7]"
					}
					]
				}
				]
			},
			{
				"name":"Elongation factors (archaeal)",
				"children":[
				{
					"name":"B-family DNA polymerases"
				},
				{
					"name":"D-family DNA polymerases"
				},
				{
					"name":"RNase H"
				},
				{
					"name":"RFC (replication factor C)"
				},
				{
					"name":"Other elongation factors",
					"children":[
					{
						"name":"111432188 DNA replication ATP-dependent helicase\/nuclease DNA2 isoform X1\tK10742 DNA2; DNA replication ATP-dependent helicase\/nuclease Dna2 [EC:5.6.2.3 3.1.-.-]"
					},
					{
						"name":"111437876 flap endonuclease 1 isoform X1\tK04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]"
					},
					{
						"name":"111448471 DNA ligase 1\tK10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"DNA Replication Termination Factors",
			"children":[
			{
				"name":"Terminus site-binding protein"
			},
			{
				"name":"DNA methylation enzymes"
			},
			{
				"name":"Prevention of re-replication factors"
			}
			]
		},
		{
			"name":"DNA Topoisomerases",
			"children":[
			{
				"name":"111462414 DNA gyrase subunit A, chloroplastic\/mitochondrial\tK02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]"
			},
			{
				"name":"111439391 DNA gyrase subunit B, chloroplastic\/mitochondrial-like\tK02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]"
			},
			{
				"name":"111459466 DNA topoisomerase 6 subunit B isoform X1\tK03167 top6B; DNA topoisomerase VI subunit B [EC:5.6.2.2]"
			}
			]
		}
		]
	}
	]
}