{
	"name":"copr03009",
	"children":[
	{
		"name":"Eukaryotic type",
		"children":[
		{
			"name":"Sno RNPs",
			"children":[
			{
				"name":"Box C\/D snoRNPs"
			},
			{
				"name":"Box H\/ACA snoRNPs"
			}
			]
		},
		{
			"name":"90S particles",
			"children":[
			{
				"name":"U3 small nucleolar RNA-associated proteins"
			},
			{
				"name":"Helicases"
			},
			{
				"name":"GTPase"
			},
			{
				"name":"RNase",
				"children":[
				{
					"name":"Cop2CBH44_24140 rnc; ribonuclease 3\tK03685 rnc; ribonuclease III [EC:3.1.26.3]"
				}
				]
			},
			{
				"name":"Kinase"
			},
			{
				"name":"Other 90S particles"
			}
			]
		},
		{
			"name":"Pre-40S particles",
			"children":[
			{
				"name":"Kinases"
			},
			{
				"name":"Export and cytoplasmic maturation factors"
			},
			{
				"name":"Other pre-40S particles"
			}
			]
		},
		{
			"name":"Pre-60S particles",
			"children":[
			{
				"name":"Helicases"
			},
			{
				"name":"GTPases"
			},
			{
				"name":"RNases",
				"children":[
				{
					"name":"RNase MRP"
				}
				]
			},
			{
				"name":"Kinases"
			},
			{
				"name":"Export and cytoplasmic maturation factors"
			},
			{
				"name":"55LCC heterohexameric ATPase complex"
			},
			{
				"name":"5-FMC complex"
			},
			{
				"name":"Ribosome quality control proteins"
			},
			{
				"name":"Other pre-60S particles"
			}
			]
		},
		{
			"name":"Other ribosome biogenesis factors",
			"children":[
			{
				"name":"Cop2CBH44_19390 era; GTPase Era\tK03595 era; GTPase"
			},
			{
				"name":"Cop2CBH44_26390 obg; GTPase Obg\tK03979 obgE; GTPase [EC:3.6.5.-]"
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic type",
		"children":[
		{
			"name":"Sno RNPs",
			"children":[
			{
				"name":"Box C\/D snoRNPs"
			},
			{
				"name":"Box H\/ACA snoRNPs"
			}
			]
		},
		{
			"name":"rRNA transcription factors",
			"children":[
			{
				"name":"Cop2CBH44_09000 molecular chaperone DnaK\tK06204 dksA; RNA polymerase-binding transcription factor"
			},
			{
				"name":"Cop2CBH44_19100 nusA; transcription termination\/antitermination protein NusA\tK02600 nusA; transcription termination\/antitermination protein NusA"
			},
			{
				"name":"Cop2CBH44_08070 N utilization substance protein B\tK03625 nusB; transcription antitermination protein NusB"
			},
			{
				"name":"Cop2CBH44_15990 transcriptional regulator\tK02601 nusG; transcription termination\/antitermination protein NusG"
			},
			{
				"name":"Cop2CBH44_25880 nusG; transcription termination\/antitermination protein NusG\tK02601 nusG; transcription termination\/antitermination protein NusG"
			}
			]
		},
		{
			"name":"rRNA modification factors",
			"children":[
			{
				"name":"16S rRNA modification factors",
				"children":[
				{
					"name":"Cop2CBH44_27470 rsmA; ribosomal RNA small subunit methyltransferase A\tK02528 ksgA; 16S rRNA (adenine1518-N6\/adenine1519-N6)-dimethyltransferase [EC:2.1.1.182]"
				},
				{
					"name":"Cop2CBH44_29280 methyltransferase\tK08316 rsmD; 16S rRNA (guanine966-N2)-methyltransferase [EC:2.1.1.171]"
				},
				{
					"name":"Cop2CBH44_00770 ribosomal RNA small subunit methyltransferase E\tK09761 rsmE; 16S rRNA (uracil1498-N3)-methyltransferase [EC:2.1.1.193]"
				},
				{
					"name":"Cop2CBH44_07380 rsmG; ribosomal RNA small subunit methyltransferase G\tK03501 gidB; 16S rRNA (guanine527-N7)-methyltransferase [EC:2.1.1.170]"
				},
				{
					"name":"Cop2CBH44_24860 rsmH; ribosomal RNA small subunit methyltransferase H\tK03438 mraW; 16S rRNA (cytosine1402-N4)-methyltransferase [EC:2.1.1.199]"
				},
				{
					"name":"Cop2CBH44_09330 S-adenosylmethionine-dependent methyltransferase\tK07056 rsmI; 16S rRNA (cytidine1402-2'-O)-methyltransferase [EC:2.1.1.198]"
				},
				{
					"name":"Cop2CBH44_31810 rsmI; ribosomal RNA small subunit methyltransferase I\tK07056 rsmI; 16S rRNA (cytidine1402-2'-O)-methyltransferase [EC:2.1.1.198]"
				}
				]
			},
			{
				"name":"23S rRNA modification factors",
				"children":[
				{
					"name":"Cop2CBH44_14100 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB\tK03218 rlmB; 23S rRNA (guanosine2251-2'-O)-methyltransferase [EC:2.1.1.185]"
				},
				{
					"name":"Cop2CBH44_03970 rlmH; ribosomal RNA large subunit methyltransferase H\tK00783 rlmH; 23S rRNA (pseudouridine1915-N3)-methyltransferase [EC:2.1.1.177]"
				},
				{
					"name":"Cop2CBH44_10770 SAM-dependent methyltransferase\tK06969 rlmI; 23S rRNA (cytosine1962-C5)-methyltransferase [EC:2.1.1.191]"
				},
				{
					"name":"Cop2CBH44_22580 RNA methyltransferase\tK25137 rlmL; 23S rRNA (guanine2445-N2)-methyltransferase [EC:2.1.1.173]"
				},
				{
					"name":"Cop2CBH44_13110 rlmN; putative dual-specificity RNA methyltransferase RlmN\tK06941 rlmN; 23S rRNA (adenine2503-C2)-methyltransferase [EC:2.1.1.192]"
				},
				{
					"name":"Cop2CBH44_10040 23S rRNA (uracil-5-)-methyltransferase RumA\tK03215 rumA; 23S rRNA (uracil1939-C5)-methyltransferase [EC:2.1.1.190]"
				},
				{
					"name":"Cop2CBH44_12310 RNA pseudouridine synthase\tK06177 rluA; tRNA pseudouridine32 synthase \/ 23S rRNA pseudouridine746 synthase [EC:5.4.99.28 5.4.99.29]"
				},
				{
					"name":"Cop2CBH44_19230 pseudouridine synthase\tK06178 rluB; 23S rRNA pseudouridine2605 synthase [EC:5.4.99.22]"
				},
				{
					"name":"Cop2CBH44_07310 RNA pseudouridine synthase\tK06180 rluD; 23S rRNA pseudouridine1911\/1915\/1917 synthase [EC:5.4.99.23]"
				},
				{
					"name":"Cop2CBH44_18990 pseudouridine synthase\tK06180 rluD; 23S rRNA pseudouridine1911\/1915\/1917 synthase [EC:5.4.99.23]"
				},
				{
					"name":"Cop2CBH44_31240 pseudouridine synthase\tK06180 rluD; 23S rRNA pseudouridine1911\/1915\/1917 synthase [EC:5.4.99.23]"
				},
				{
					"name":"Cop2CBH44_11580 ermC; 23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(C)\tK00561 ermC; 23S rRNA (adenine-N6)-dimethyltransferase [EC:2.1.1.184]"
				}
				]
			}
			]
		},
		{
			"name":"ribosomal protein modification factors",
			"children":[
			{
				"name":"Cop2CBH44_26970 hypothetical protein\tK03789 rimI; [ribosomal protein S18]-alanine N-acetyltransferase \/ [ribosomal protein L31]-L-lysine N-acetyltransferase [EC:2.3.1.266 2.3.1.338]"
			},
			{
				"name":"Cop2CBH44_12800 rimM; ribosome maturation factor RimM\tK02860 rimM; 16S rRNA processing protein RimM"
			},
			{
				"name":"Cop2CBH44_15670 rimO; ribosomal protein S12 methylthiotransferase RimO\tK14441 rimO; ribosomal protein S12 methylthiotransferase [EC:2.8.4.4]"
			},
			{
				"name":"Cop2CBH44_06730 prmA; ribosomal protein L11 methyltransferase\tK02687 prmA; ribosomal protein L11 methyltransferase [EC:2.1.1.-]"
			}
			]
		},
		{
			"name":"rRNA processing factors",
			"children":[
			{
				"name":"Cop2CBH44_24140 rnc; ribonuclease 3\tK03685 rnc; ribonuclease III [EC:3.1.26.3]"
			},
			{
				"name":"Cop2CBH44_17840 ribonuclease G\tK08301 rng; ribonuclease G [EC:3.1.26.-]"
			},
			{
				"name":"Cop2CBH44_19950 putative pre-16S rRNA nuclease\tK07447 ruvX; putative pre-16S rRNA nuclease [EC:3.1.-.-]"
			}
			]
		},
		{
			"name":"rRNA helicases",
			"children":[
			{
				"name":"Cop2CBH44_21960 DEAD\/DEAH box helicase\tK05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7]"
			}
			]
		},
		{
			"name":"GTPases",
			"children":[
			{
				"name":"Cop2CBH44_19390 era; GTPase Era\tK03595 era; GTPase"
			},
			{
				"name":"Cop2CBH44_30150 rsgA; putative ribosome biogenesis GTPase RsgA\tK06949 rsgA; ribosome biogenesis GTPase \/ thiamine phosphate phosphatase [EC:3.6.1.- 3.1.3.100]"
			},
			{
				"name":"Cop2CBH44_19380 der; GTPase Der\tK03977 engA; GTPase"
			},
			{
				"name":"Cop2CBH44_26390 obg; GTPase Obg\tK03979 obgE; GTPase [EC:3.6.5.-]"
			},
			{
				"name":"Cop2CBH44_26090 hflX; GTPase HflX\tK03665 hflX; GTPase"
			}
			]
		},
		{
			"name":"Other maturation factors",
			"children":[
			{
				"name":"Cop2CBH44_05960 threonylcarbamoyl-AMP synthase\tK07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]"
			},
			{
				"name":"Cop2CBH44_10010 GTP pyrophosphokinase\tK01139 spoT; GTP diphosphokinase \/ guanosine-3',5'-bis(diphosphate) 3'-diphosphatase [EC:2.7.6.5 3.1.7.2]"
			},
			{
				"name":"Cop2CBH44_18200 GTP pyrophosphokinase\tK01139 spoT; GTP diphosphokinase \/ guanosine-3',5'-bis(diphosphate) 3'-diphosphatase [EC:2.7.6.5 3.1.7.2]"
			},
			{
				"name":"Cop2CBH44_21730 ribosome-binding factor A\tK02834 rbfA; ribosome-binding factor A"
			},
			{
				"name":"Cop2CBH44_19110 rimP; ribosome maturation factor RimP\tK09748 rimP; ribosome maturation factor RimP"
			},
			{
				"name":"Cop2CBH44_19870 rsfS; ribosomal silencing factor RsfS\tK09710 ybeB; ribosome-associated protein"
			},
			{
				"name":"Cop2CBH44_25860 RNA polymerase subunit sigma-54\tK05808 hpf; ribosome hibernation promoting factor"
			},
			{
				"name":"Cop2CBH44_22360 ychF; ribosome-binding ATPase YchF\tK06942 ychF; ribosome-binding ATPase"
			},
			{
				"name":"Cop2CBH44_19420 hypothetical protein\tK07040 yceD; DUF177 domain-containing protein"
			}
			]
		}
		]
	},
	{
		"name":"Related small nucleolar RNAs",
		"children":[
		{
			"name":"Box C\/D snoRNAs",
			"children":[
			{
				"name":"SnoRNAs involved in processing reactions"
			},
			{
				"name":"SnoRNAs act as guides for 2'-O-ribose methylation"
			}
			]
		},
		{
			"name":"Box H\/ACA snoRNAs",
			"children":[
			{
				"name":"SnoRNAs involved in processing reactions"
			},
			{
				"name":"SnoRNAs act as guides for pseudouridynation"
			}
			]
		},
		{
			"name":"Other snoRNA"
		}
		]
	}
	]
}
