{
	"name":"cpla03016",
	"children":[
	{
		"name":"Eukaryotic type",
		"children":[
		{
			"name":"5'processing factors",
			"children":[
			{
				"name":"Ribonucrease P",
				"children":[
				{
					"name":"122548832 pop1; ribonucleases P\/MRP protein subunit POP1\tK01164 POP1; ribonuclease P\/MRP protein subunit POP1 [EC:3.1.26.5]"
				},
				{
					"name":"122558378 pop4; ribonuclease P protein subunit p29 isoform X1\tK03538 POP4; ribonuclease P protein subunit POP4 [EC:3.1.26.5]"
				},
				{
					"name":"122562778 pop5; ribonuclease P\/MRP protein subunit POP5\tK03537 POP5; ribonuclease P\/MRP protein subunit POP5 [EC:3.1.26.5]"
				},
				{
					"name":"122561071 rpp30; ribonuclease P protein subunit p30 isoform X1\tK03539 RPP1; ribonuclease P\/MRP protein subunit RPP1 [EC:3.1.26.5]"
				},
				{
					"name":"122559036 rpp14; ribonuclease P protein subunit p14 isoform X1\tK14529 RPP14; ribonuclease P protein subunit RPP14 [EC:3.1.26.5]"
				},
				{
					"name":"122544432 pop7; ribonuclease P protein subunit p20\tK14527 RPP20; ribonuclease P\/MRP protein subunit RPP20 [EC:3.1.26.5]"
				},
				{
					"name":"122542480 ribonuclease P protein subunit p25-like protein\tK14525 RPP25; ribonucleases P\/MRP protein subunit RPP25 [EC:3.1.26.5]"
				},
				{
					"name":"122544308 rpp25l; ribonuclease P protein subunit p25-like protein\tK14525 RPP25; ribonucleases P\/MRP protein subunit RPP25 [EC:3.1.26.5]"
				},
				{
					"name":"122549989 rpp38; ribonuclease P protein subunit p38\tK14523 RPP38; ribonucleases P\/MRP protein subunit RPP38 [EC:3.1.26.5]"
				},
				{
					"name":"122564507 rpp40; ribonuclease P protein subunit p40\tK14530 RPP40; ribonucleases P\/MRP protein subunit RPP40 [EC:3.1.26.5]"
				}
				]
			}
			]
		},
		{
			"name":"3'processing and CCA adding factors",
			"children":[
			{
				"name":"3'processing factors",
				"children":[
				{
					"name":"122539904 elac1; zinc phosphodiesterase ELAC protein 1\tK00784 rnz; ribonuclease Z [EC:3.1.26.11]"
				},
				{
					"name":"122562033 elac2; zinc phosphodiesterase ELAC protein 2\tK00784 rnz; ribonuclease Z [EC:3.1.26.11]"
				},
				{
					"name":"122542898 rnaset2l; ribonuclease T2-like isoform X1\tK01166 RNASET2; ribonuclease T2 [EC:4.6.1.19]"
				},
				{
					"name":"122553045 ribonuclease T2-like isoform X1\tK01166 RNASET2; ribonuclease T2 [EC:4.6.1.19]"
				},
				{
					"name":"122560549 ptcd1; pentatricopeptide repeat-containing protein 1, mitochondrial\tK17710 PTCD1; pentatricopeptide repeat domain-containing protein 1"
				}
				]
			},
			{
				"name":"CCA adding factors",
				"children":[
				{
					"name":"122559098 trnt1; CCA tRNA nucleotidyltransferase 1, mitochondrial\tK00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]"
				}
				]
			}
			]
		},
		{
			"name":"tRNA spricing factors",
			"children":[
			{
				"name":"tRNA splicing endonuclease complex",
				"children":[
				{
					"name":"122558959 tsen2; tRNA-splicing endonuclease subunit Sen2 isoform X1\tK15322 TSEN2; tRNA-splicing endonuclease subunit Sen2 [EC:4.6.1.16]"
				},
				{
					"name":"122554609 tsen15; tRNA-splicing endonuclease subunit Sen15 isoform X1\tK15324 TSEN15; tRNA-splicing endonuclease subunit Sen15"
				}
				]
			},
			{
				"name":"tRNA splicing ligase complex",
				"children":[
				{
					"name":"122559623 rtcb; RNA-splicing ligase RtcB homolog\tK14415 RTCB; tRNA-splicing ligase RtcB (3'-phosphate\/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8]"
				},
				{
					"name":"122550667 c6h2orf49; ashwin\tK15432 ASW; ashwin"
				},
				{
					"name":"122553600 rtraf; RNA transcription, translation and transport factor protein\tK15433 CGI99; RLL motif containing protein 1"
				},
				{
					"name":"122553735 fam98b; protein FAM98B isoform X1\tK15434 FAM98B; protein FAM98B"
				},
				{
					"name":"122541035 ddx1; ATP-dependent RNA helicase DDX1\tK13177 DDX1; ATP-dependent RNA helicase DDX1 [EC:5.6.2.7]"
				},
				{
					"name":"122563461 zbtb8os; protein archease\tK24956 ZBTB8OS; protein archease"
				}
				]
			},
			{
				"name":"Other tRNA splicing factors"
			}
			]
		},
		{
			"name":"tRNA transport factors",
			"children":[
			{
				"name":"tRNA export factors",
				"children":[
				{
					"name":"122562146 GTP-binding nuclear protein Ran-like\tK07936 RAN; GTP-binding nuclear protein Ran"
				},
				{
					"name":"122562500 ran; GTP-binding nuclear protein Ran\tK07936 RAN; GTP-binding nuclear protein Ran"
				},
				{
					"name":"122559845 xpot; exportin-T isoform X1\tK14288 XPOT; exportin-T"
				},
				{
					"name":"122552899 exportin-1\tK14290 XPO1; exportin-1"
				},
				{
					"name":"122553379 exportin-1-like\tK14290 XPO1; exportin-1"
				},
				{
					"name":"122552710 exportin-5 isoform X1\tK14289 XPO5; exportin-5"
				},
				{
					"name":"122542581 elongation factor 1-alpha 1 isoform X1\tK03231 EEF1A; elongation factor 1-alpha"
				},
				{
					"name":"122549169 elongation factor 1-alpha-like isoform X1\tK03231 EEF1A; elongation factor 1-alpha"
				},
				{
					"name":"122558889 elongation factor 1-alpha 1-like\tK03231 EEF1A; elongation factor 1-alpha"
				},
				{
					"name":"122560322 elongation factor 1-alpha 2\tK03231 EEF1A; elongation factor 1-alpha"
				},
				{
					"name":"122563683 elongation factor 1-alpha 1-like\tK03231 EEF1A; elongation factor 1-alpha"
				},
				{
					"name":"122547062 scyl1; N-terminal kinase-like protein\tK08876 SCYL1; SCY1-like protein 1"
				},
				{
					"name":"122542099 GTP-binding protein 1-like isoform X1\tK24887 GTPBP1; GTP-binding protein 1"
				}
				]
			},
			{
				"name":"tRNA import factors",
				"children":[
				{
					"name":"122542211 transportin-3-like isoform X1\tK15436 TRPO3; transportin-3"
				},
				{
					"name":"122561789 tnpo3; transportin-3\tK15436 TRPO3; transportin-3"
				}
				]
			}
			]
		},
		{
			"name":"Aminoacyl-tRNA synthetases (AARSs)",
			"children":[
			{
				"name":"Multi-aminoacyl-tRNA synthetase complex (MSC)",
				"children":[
				{
					"name":"122552809 eprs1; bifunctional glutamate\/proline--tRNA ligase isoform X1\tK14163 EPRS; bifunctional glutamyl\/prolyl-tRNA synthetase [EC:6.1.1.17 6.1.1.15]"
				},
				{
					"name":"122560720 ears2; probable glutamate--tRNA ligase, mitochondrial\tK01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]"
				},
				{
					"name":"122554758 pars2; probable proline--tRNA ligase, mitochondrial\tK01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]"
				},
				{
					"name":"122552806 iars2; isoleucine--tRNA ligase, mitochondrial\tK01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]"
				},
				{
					"name":"122558934 iars1; isoleucine--tRNA ligase, cytoplasmic\tK01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]"
				},
				{
					"name":"122556520 lars1b; leucine--tRNA ligase, cytoplasmic\tK01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]"
				},
				{
					"name":"122564532 lars2; probable leucine--tRNA ligase, mitochondrial isoform X1\tK01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]"
				},
				{
					"name":"122557226 mars2; methionine--tRNA ligase, mitochondrial\tK01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]"
				},
				{
					"name":"122559267 qars1; glutamine--tRNA ligase\tK01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18]"
				},
				{
					"name":"122548358 rars2; probable arginine--tRNA ligase, mitochondrial isoform X1\tK01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]"
				},
				{
					"name":"122556532 rars1; arginine--tRNA ligase, cytoplasmic isoform X1\tK01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]"
				},
				{
					"name":"122558297 kars1; lysine--tRNA ligase isoform X1\tK04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]"
				},
				{
					"name":"122551694 dars1; aspartate--tRNA ligase, cytoplasmic\tK22503 DARS1; aspartyl-tRNA synthetase [EC:6.1.1.12]"
				},
				{
					"name":"122554636 dars2; aspartate--tRNA ligase, mitochondrial isoform X1\tK01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]"
				},
				{
					"name":"122539472 aimp1a; aminoacyl tRNA synthase complex-interacting multifunctional protein 1a isoform X1\tK15437 AIMP1; aminoacyl tRNA synthase complex-interacting multifunctional protein 1"
				},
				{
					"name":"122560591 aimp2; aminoacyl tRNA synthase complex-interacting multifunctional protein 2\tK15438 AIMP2; aminoacyl tRNA synthase complex-interacting multifunctional protein 2"
				},
				{
					"name":"122549196 eef1e1; eukaryotic translation elongation factor 1 epsilon-1\tK15439 EEF1E1; eukaryotic translation elongation factor 1 epsilon-1"
				}
				]
			},
			{
				"name":"Other AARSs",
				"children":[
				{
					"name":"122548560 aars2; alanine--tRNA ligase, mitochondrial isoform X1\tK01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]"
				},
				{
					"name":"122558586 aars1; alanine--tRNA ligase, cytoplasmic\tK01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]"
				},
				{
					"name":"122540371 nars1; asparagine--tRNA ligase, cytoplasmic\tK01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]"
				},
				{
					"name":"122550626 nars2; probable asparagine--tRNA ligase, mitochondrial isoform X1\tK01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]"
				},
				{
					"name":"122550172 gars1; glycine--tRNA ligase\tK01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]"
				},
				{
					"name":"122542508 threonine--tRNA ligase 1, cytoplasmic-like\tK01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]"
				},
				{
					"name":"122549017 tars1; threonine--tRNA ligase 1, cytoplasmic\tK01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]"
				},
				{
					"name":"122542687 sars2; serine--tRNA ligase, mitochondrial\tK01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]"
				},
				{
					"name":"122563191 sars1; serine--tRNA ligase, cytoplasmic\tK01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]"
				},
				{
					"name":"122551033 cars2; probable cysteine--tRNA ligase, mitochondrial\tK01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]"
				},
				{
					"name":"122548333 vars1; valine--tRNA ligase isoform X1\tK01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]"
				},
				{
					"name":"122556433 hars; histidine--tRNA ligase isoform X1\tK01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]"
				},
				{
					"name":"122552231 farsa; phenylalanine--tRNA ligase alpha subunit\tK01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]"
				},
				{
					"name":"122564508 fars2; phenylalanine--tRNA ligase, mitochondrial isoform X1\tK01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]"
				},
				{
					"name":"122555850 farsb; phenylalanine--tRNA ligase beta subunit\tK01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]"
				},
				{
					"name":"122559568 yars2; tyrosine--tRNA ligase, mitochondrial\tK01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]"
				},
				{
					"name":"122563635 yars1; tyrosine--tRNA ligase, cytoplasmic\tK01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]"
				},
				{
					"name":"122553520 tryptophan--tRNA ligase, cytoplasmic\tK01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]"
				},
				{
					"name":"122555202 wars2; tryptophan--tRNA ligase, mitochondrial\tK01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]"
				}
				]
			},
			{
				"name":"Trans-editing factors",
				"children":[
				{
					"name":"122553049 dtd1; D-aminoacyl-tRNA deacylase 1\tK07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]"
				},
				{
					"name":"122553766 dtd2; D-aminoacyl-tRNA deacylase 2\tK07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]"
				},
				{
					"name":"122539871 aarsd1; alanyl-tRNA editing protein Aarsd1\tK07050 AARSD1; misacylated tRNA(Ala) deacylase [EC:3.1.1.-]"
				}
				]
			},
			{
				"name":"AARS associated factors",
				"children":[
				{
					"name":"122540051 tRNA selenocysteine 1-associated protein 1-like isoform X1\tK25102 TRNAU1AP; tRNA selenocysteine 1-associated protein 1"
				},
				{
					"name":"122563506 tRNA selenocysteine 1-associated protein 1-like isoform X1\tK25102 TRNAU1AP; tRNA selenocysteine 1-associated protein 1"
				},
				{
					"name":"122548405 hint2; histidine triad nucleotide-binding protein 2, mitochondrial isoform X1\tK02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]"
				},
				{
					"name":"122561969 hint1; histidine triad nucleotide-binding protein 1\tK02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]"
				},
				{
					"name":"122544589 hint3; histidine triad nucleotide-binding protein 3\tK12150 HINT3; adenosine 5'-monophosphoramidase HINT3 [EC:3.9.1.-]"
				}
				]
			}
			]
		},
		{
			"name":"tRNA modification factors",
			"children":[
			{
				"name":"Deaminases",
				"children":[
				{
					"name":"122558298 adat1; tRNA-specific adenosine deaminase 1 isoform X1\tK15440 TAD1; tRNA-specific adenosine deaminase 1 [EC:3.5.4.34]"
				},
				{
					"name":"122552589 adat2; tRNA-specific adenosine deaminase 2\tK15441 TAD2; tRNA-specific adenosine deaminase 2 [EC:3.5.4.-]"
				},
				{
					"name":"122551244 adat3; probable inactive tRNA-specific adenosine deaminase-like protein 3 isoform X1\tK15442 TAD3; tRNA-specific adenosine deaminase 3"
				}
				]
			},
			{
				"name":"Dihydorouridine synthases",
				"children":[
				{
					"name":"122562134 dus1l; tRNA-dihydrouridine(16\/17) synthase [NAD(P)(+)]-like\tK05542 DUS1; tRNA-dihydrouridine synthase 1 [EC:1.3.1.88]"
				},
				{
					"name":"122558445 dus2; tRNA-dihydrouridine(20) synthase [NAD(P)+]-like\tK05543 DUS2; tRNA-dihydrouridine synthase 2 [EC:1.3.1.91]"
				},
				{
					"name":"122549975 dus3l; tRNA-dihydrouridine(47) synthase [NAD(P)(+)]-like isoform X1\tK05544 DUS3; tRNA-dihydrouridine synthase 3 [EC:1.3.1.89]"
				},
				{
					"name":"122561681 dus4l; tRNA-dihydrouridine(20a\/20b) synthase [NAD(P)+]-like isoform X1\tK05545 DUS4; tRNA-dihydrouridine synthase 4 [EC:1.3.1.90]"
				}
				]
			},
			{
				"name":"Methylthiotransferase",
				"children":[
				{
					"name":"122560019 cdk5rap1; CDK5 regulatory subunit-associated protein 1\tK06168 CDK5RAP1; tRNA-2-methylthio-N6-dimethylallyladenosine synthase [EC:2.8.4.3]"
				},
				{
					"name":"122564268 cdkal1; threonylcarbamoyladenosine tRNA methylthiotransferase\tK15865 CDKAL1; threonylcarbamoyladenosine tRNA methylthiotransferase [EC:2.8.4.5]"
				}
				]
			},
			{
				"name":"Methyltransferases",
				"children":[
				{
					"name":"122552288 trmt1; tRNA (guanine(26)-N(2))-dimethyltransferase isoform X1\tK00555 TRMT1; tRNA (guanine26-N2\/guanine27-N2)-dimethyltransferase [EC:2.1.1.215 2.1.1.216]"
				},
				{
					"name":"122562528 trmt2a; tRNA (uracil-5-)-methyltransferase homolog A isoform X1\tK15332 TRMT2A; tRNA (uracil-5-)-methyltransferase [EC:2.1.1.-]"
				},
				{
					"name":"122557062 trmt2b; tRNA (uracil(54)-C(5))-methyltransferase homolog-B\tK15331 TRMT2B; tRNA (uracil-5-)-methyltransferase [EC:2.1.1.35]"
				},
				{
					"name":"122552628 tarbp1; probable methyltransferase TARBP1 isoform X1\tK15333 TRM3; tRNA guanosine-2'-O-methyltransferase [EC:2.1.1.34]"
				},
				{
					"name":"122549724 nsun2; RNA cytosine C(5)-methyltransferase NSUN2 isoform X1\tK15335 NSUN2; tRNA (cytosine34-C5)-methyltransferase [EC:2.1.1.203]"
				},
				{
					"name":"122555105 nsun3; tRNA (cytosine(34)-C(5))-methyltransferase, mitochondrial\tK21969 NSUN3; tRNA (cytosine34-C5)-methyltransferase [EC:2.1.1.-]"
				},
				{
					"name":"122550018 nsun6; tRNA (cytosine(72)-C(5))-methyltransferase NSUN6 isoform X1\tK21971 NSUN6; methyltransferase NSUN6 [EC:2.1.1.-]"
				},
				{
					"name":"122553463 trmt5; tRNA (guanine(37)-N1)-methyltransferase isoform X1\tK15429 TRM5; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228]"
				},
				{
					"name":"122548491 trmt61b; tRNA (adenine(58)-N(1))-methyltransferase, mitochondrial\tK07442 TRM61; tRNA (adenine57-N1\/adenine58-N1)-methyltransferase catalytic subunit [EC:2.1.1.219 2.1.1.220]"
				},
				{
					"name":"122553544 trmt61a; tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A isoform X1\tK07442 TRM61; tRNA (adenine57-N1\/adenine58-N1)-methyltransferase catalytic subunit [EC:2.1.1.219 2.1.1.220]"
				},
				{
					"name":"122553077 trmt6; tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 isoform X1\tK03256 TRM6; tRNA (adenine58-N1)-methyltransferase non-catalytic subunit"
				},
				{
					"name":"122543276 mettl1; tRNA (guanine-N(7)-)-methyltransferase isoform X1\tK03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33]"
				},
				{
					"name":"122540020 mettl2a; tRNA N(3)-methylcytidine methyltransferase METTL2 isoform X1\tK24974 METTL2; tRNA N(3)-methylcytidine methyltransferase METTL2 [EC:2.1.1.-]"
				},
				{
					"name":"122564426 mettl6; tRNA N(3)-methylcytidine methyltransferase METTL6 isoform X1\tK00599 METTL6; tRNA N(3)-methylcytidine methyltransferase METTL6 [EC:2.1.1.-]"
				},
				{
					"name":"122550701 alkbh8; alkylated DNA repair protein alkB homolog 8\tK10770 ALKBH8; alkylated DNA repair protein alkB homolog 8 [EC:1.14.11.- 2.1.1.229]"
				},
				{
					"name":"122549999 probable tRNA methyltransferase 9B\tK28867 TRMT9B; tRNA methyltransferase 9B [EC:2.1.1.-]"
				},
				{
					"name":"122539513 trmt10a; RNA (guanine-9-)-methyltransferase domain-containing protein 2\tK15445 TRMT10; tRNA (guanine9-N1)-methyltransferase [EC:2.1.1.221]"
				},
				{
					"name":"122544561 trmt11; tRNA (guanine(10)-N2)-methyltransferase homolog isoform X1\tK15430 TRM11; tRNA (guanine10-N2)-methyltransferase [EC:2.1.1.214]"
				},
				{
					"name":"122554528 trmt13; tRNA:m(4)X modification enzyme TRM13 homolog\tK15446 TRM13; tRNA:m4X modification enzyme [EC:2.1.1.225]"
				},
				{
					"name":"122554131 trmt44; probable tRNA (uracil-O(2)-)-methyltransferase isoform X1\tK15447 TRM44; tRNASer (uridine44-2'-O)-methyltransferase [EC:2.1.1.211]"
				},
				{
					"name":"122559153 thumpd3; THUMP domain-containing protein 3 isoform X1\tK28362 THUMPD3; tRNA (guanine(6\/7)-N(2))-methyltransferase [EC:2.1.1.256 2.1.1.-]"
				},
				{
					"name":"122544026 trmt112; multifunctional methyltransferase subunit TRM112-like protein\tK15448 TRM112; multifunctional methyltransferase subunit TRM112"
				},
				{
					"name":"122550008 trdmt1; tRNA (cytosine(38)-C(5))-methyltransferase isoform X1\tK15336 TRDMT1; tRNA (cytosine38-C5)-methyltransferase [EC:2.1.1.204]"
				},
				{
					"name":"122563373 trmo; tRNA (adenine(37)-N6)-methyltransferase\tK22900 TRMO; tRNA (adenine37-N6)-methyltransferase [EC:2.1.1.-]"
				},
				{
					"name":"122564083 tyw1; S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1 isoform X1\tK15449 TYW1; tRNA wybutosine-synthesizing protein 1 [EC:4.1.3.44]"
				},
				{
					"name":"122557175 trmt12; tRNA wybutosine-synthesizing protein 2 homolog\tK07055 TRM12; tRNA wybutosine-synthesizing protein 2 [EC:2.5.1.114]"
				},
				{
					"name":"122554095 tyw3; tRNA wybutosine-synthesizing protein 3 homolog isoform X1\tK15450 TYW3; tRNA wybutosine-synthesizing protein 3 [EC:2.1.1.282]"
				},
				{
					"name":"122551296 lcmt2; tRNA wybutosine-synthesizing protein 4 isoform X1\tK15451 PPM2; tRNA wybutosine-synthesizing protein 4 [EC:2.1.1.290 2.3.1.231]"
				},
				{
					"name":"122551284 tyw5; tRNA wybutosine-synthesizing protein 5 isoform X1\tK18066 TYW5; tRNA wybutosine-synthesizing protein 5 [EC:1.14.11.42]"
				}
				]
			},
			{
				"name":"Psudouridine synthases",
				"children":[
				{
					"name":"122562505 pus1; tRNA pseudouridine synthase A\tK06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]"
				},
				{
					"name":"122546018 pus3; tRNA pseudouridine(38\/39) synthase\tK01855 PUS3; tRNA pseudouridine38\/39 synthase [EC:5.4.99.45]"
				},
				{
					"name":"122561215 trub1; probable tRNA pseudouridine synthase 1 isoform X1\tK03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]"
				},
				{
					"name":"122559511 pus7l; pseudouridylate synthase 7 homolog-like protein isoform X1\tK06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]"
				},
				{
					"name":"122561759 pus7; pseudouridylate synthase 7 homolog isoform X1\tK06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]"
				},
				{
					"name":"122552894 pus10; putative tRNA pseudouridine synthase Pus10 isoform X1\tK07583 PUS10; tRNA pseudouridine synthase 10 [EC:5.4.99.25]"
				},
				{
					"name":"122546327 mitochondrial RNA pseudouridine synthase rpusd4-like\tK22538 RPUSD4; mitochondrial RNA pseudouridine synthase RPUSD4 [EC:5.4.99.-]"
				}
				]
			},
			{
				"name":"Thiolation factors",
				"children":[
				{
					"name":"122561686 trmu; mitochondrial tRNA-specific 2-thiouridylase 1 isoform X1\tK21027 TRMU; tRNA-5-taurinomethyluridine 2-sulfurtransferase [EC:2.8.1.14]"
				},
				{
					"name":"122562802 ctu1; cytoplasmic tRNA 2-thiolation protein 1 isoform X1\tK14168 CTU1; cytoplasmic tRNA 2-thiolation protein 1 [EC:2.7.7.-]"
				},
				{
					"name":"122558316 ctu2; cytoplasmic tRNA 2-thiolation protein 2 isoform X1\tK14169 CTU2; cytoplasmic tRNA 2-thiolation protein 2"
				},
				{
					"name":"122548301 nfs1; cysteine desulfurase, mitochondrial\tK04487 iscS; cysteine desulfurase [EC:2.8.1.7]"
				},
				{
					"name":"122564617 urm1; ubiquitin-related modifier 1\tK12161 URM1; ubiquitin related modifier 1"
				},
				{
					"name":"122552688 mocs3; adenylyltransferase and sulfurtransferase MOCS3 isoform X1\tK11996 MOCS3; adenylyltransferase and sulfurtransferase [EC:2.7.7.80 2.8.1.11]"
				}
				]
			},
			{
				"name":"KEOPS\/EKC complex",
				"children":[
				{
					"name":"122560250 tp53rk; EKC\/KEOPS complex subunit TP53RK\tK08851 TP53RK; TP53 regulating kinase and related kinases [EC:2.7.11.1]"
				},
				{
					"name":"122551245 osgepl1; probable tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial isoform X1\tK01409 OSGEP; N6-L-threonylcarbamoyladenine synthase [EC:2.3.1.234]"
				},
				{
					"name":"122561642 tprkb; EKC\/KEOPS complex subunit TPRKB\tK15901 TPRKB; EKC\/KEOPS complex subunit TPRKB\/CGI121"
				},
				{
					"name":"122540188 L antigen family member 3-like isoform X1\tK15902 LAGE3; EKC\/KEOPS complex subunit LAGE3\/PCC1"
				},
				{
					"name":"122553436 si:dkeyp-55f12.3; uncharacterized protein si:dkeyp-55f12.3\tK15903 GON7; EKC\/KEOPS complex subunit GON7"
				}
				]
			},
			{
				"name":"Elongator complex",
				"children":[
				{
					"name":"122563031 elp1; elongator complex protein 1\tK11373 ELP1; elongator complex protein 1"
				},
				{
					"name":"122549845 elp2; elongator complex protein 2 isoform X1\tK11374 ELP2; elongator complex protein 2"
				},
				{
					"name":"122542560 elp3; elongator complex protein 3 isoform X1\tK07739 ELP3; elongator complex protein 3 (tRNA carboxymethyluridine synthase) [EC:2.3.1.311]"
				},
				{
					"name":"122557697 elp4; elongator complex protein 4 isoform X1\tK11375 ELP4; elongator complex protein 4"
				},
				{
					"name":"122543428 elp5; elongator complex protein 5\tK11376 ELP5; elongator complex protein 5"
				},
				{
					"name":"122548934 elp6; elongator complex protein 6 isoform X1\tK11377 ELP6; elongator complex protein 6"
				}
				]
			},
			{
				"name":"Elongator related proteins",
				"children":[
				{
					"name":"122550670 dph3; DPH3 homolog\tK15455 DPH3; diphthamide biosynthesis protein 3"
				},
				{
					"name":"122542607 kti12; protein KTI12 homolog\tK15456 KTI12; protein KTI12"
				}
				]
			},
			{
				"name":"Other tRNA modification factors",
				"children":[
				{
					"name":"122563393 yrdc; yrdC domain-containing protein, mitochondrial\tK07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]"
				},
				{
					"name":"122563756 trit1; tRNA dimethylallyltransferase isoform X1\tK00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]"
				},
				{
					"name":"122554633 gtpbp3; tRNA modification GTPase GTPBP3, mitochondrial\tK03650 mnmE; tRNA modification GTPase [EC:3.6.-.-]"
				},
				{
					"name":"122540158 qtrt1; queuine tRNA-ribosyltransferase catalytic subunit 1\tK00777 QTRT1; queuine tRNA-ribosyltransferase catalytic subunit [EC:2.4.2.64]"
				},
				{
					"name":"122555029 qtrt2; queuine tRNA-ribosyltransferase accessory subunit 2 isoform X1\tK15407 QTRT2; queuine tRNA-ribosyltransferase accessory subunit"
				},
				{
					"name":"122561871 sephs1; selenide, water dikinase 1\tK01008 selD; selenide, water dikinase [EC:2.7.9.3]"
				},
				{
					"name":"122560820 thumpd1; THUMP domain-containing protein 1 isoform X1\tK06963 TAN1; tRNA acetyltransferase TAN1"
				},
				{
					"name":"122556795 thg1l; probable tRNA(His) guanylyltransferase isoform X1\tK10761 THG1; tRNA(His) guanylyltransferase [EC:2.7.7.79]"
				},
				{
					"name":"122540728 arginyl-tRNA--protein transferase 1-like isoform X1\tK00685 ATE1; arginyl-tRNA---protein transferase [EC:2.3.2.8]"
				},
				{
					"name":"122561177 arginyl-tRNA--protein transferase 1 isoform X1\tK00685 ATE1; arginyl-tRNA---protein transferase [EC:2.3.2.8]"
				},
				{
					"name":"122558824 dalrd3; DALR anticodon-binding domain-containing protein 3 isoform X1\tK24973 DALRD3; DALR anticodon-binding domain-containing protein 3"
				}
				]
			}
			]
		},
		{
			"name":"tRNA degradation factors",
			"children":[
			{
				"name":"TRAMP complex",
				"children":[
				{
					"name":"122549722 tent4a; terminal nucleotidyltransferase 4A isoform X1\tK03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5\/7 [EC:2.7.7.19]"
				},
				{
					"name":"122558409 tent4b; terminal nucleotidyltransferase 4B\tK03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5\/7 [EC:2.7.7.19]"
				},
				{
					"name":"122564563 zcchc7; zinc finger CCHC domain-containing protein 7\tK12597 AIR1_2; protein AIR1\/2"
				},
				{
					"name":"122549237 mtrex; exosome RNA helicase MTR4\tK12598 MTR4; ATP-dependent RNA helicase DOB1 [EC:5.6.2.6]"
				}
				]
			},
			{
				"name":"Rapid tRNA decay (RTD) pathway factors",
				"children":[
				{
					"name":"122556219 xrn1; 5'-3' exoribonuclease 1 isoform X1\tK12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]"
				},
				{
					"name":"122553061 xrn2; 5'-3' exoribonuclease 2 isoform X1\tK12619 XRN2; 5'-3' exoribonuclease 2 [EC:3.1.13.-]"
				},
				{
					"name":"122552808 bpnt1; 3'(2'),5'-bisphosphate nucleotidase 1\tK01082 cysQ; 3'(2'), 5'-bisphosphate nucleotidase [EC:3.1.3.7]"
				}
				]
			},
			{
				"name":"Other tRNA degradation factors",
				"children":[
				{
					"name":"122561063 interferon-induced protein with tetratricopeptide repeats 1-like isoform X1\tK24850 IFIT5; interferon-induced protein with tetratricopeptide repeats 5"
				},
				{
					"name":"122561065 interferon-induced protein with tetratricopeptide repeats 5-like\tK24850 IFIT5; interferon-induced protein with tetratricopeptide repeats 5"
				},
				{
					"name":"122561066 interferon-induced protein with tetratricopeptide repeats 5-like isoform X1\tK24850 IFIT5; interferon-induced protein with tetratricopeptide repeats 5"
				},
				{
					"name":"122561067 interferon-induced protein with tetratricopeptide repeats 5-like isoform X1\tK24850 IFIT5; interferon-induced protein with tetratricopeptide repeats 5"
				},
				{
					"name":"122561375 interferon-induced protein with tetratricopeptide repeats 5-like\tK24850 IFIT5; interferon-induced protein with tetratricopeptide repeats 5"
				},
				{
					"name":"122561376 interferon-induced protein with tetratricopeptide repeats 1-like\tK24850 IFIT5; interferon-induced protein with tetratricopeptide repeats 5"
				},
				{
					"name":"122561377 interferon-induced protein with tetratricopeptide repeats 5-like\tK24850 IFIT5; interferon-induced protein with tetratricopeptide repeats 5"
				},
				{
					"name":"122561378 interferon-induced protein with tetratricopeptide repeats 5-like\tK24850 IFIT5; interferon-induced protein with tetratricopeptide repeats 5"
				},
				{
					"name":"122561379 interferon-induced protein with tetratricopeptide repeats 5-like\tK24850 IFIT5; interferon-induced protein with tetratricopeptide repeats 5"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic type",
		"children":[
		{
			"name":"5'processing factors",
			"children":[
			{
				"name":"Ribonucrease P"
			}
			]
		},
		{
			"name":"3'processing and CCA adding factors",
			"children":[
			{
				"name":"3'processing factors",
				"children":[
				{
					"name":"122539904 elac1; zinc phosphodiesterase ELAC protein 1\tK00784 rnz; ribonuclease Z [EC:3.1.26.11]"
				},
				{
					"name":"122562033 elac2; zinc phosphodiesterase ELAC protein 2\tK00784 rnz; ribonuclease Z [EC:3.1.26.11]"
				},
				{
					"name":"122542898 rnaset2l; ribonuclease T2-like isoform X1\tK01166 RNASET2; ribonuclease T2 [EC:4.6.1.19]"
				},
				{
					"name":"122553045 ribonuclease T2-like isoform X1\tK01166 RNASET2; ribonuclease T2 [EC:4.6.1.19]"
				}
				]
			},
			{
				"name":"CCA adding factors",
				"children":[
				{
					"name":"122559098 trnt1; CCA tRNA nucleotidyltransferase 1, mitochondrial\tK00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]"
				}
				]
			}
			]
		},
		{
			"name":"tRNA spricing factors",
			"children":[
			{
				"name":"tRNA splicing endonucleases"
			},
			{
				"name":"tRNA splicing ligases",
				"children":[
				{
					"name":"122559623 rtcb; RNA-splicing ligase RtcB homolog\tK14415 RTCB; tRNA-splicing ligase RtcB (3'-phosphate\/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8]"
				}
				]
			},
			{
				"name":"Other tRNA splicing factors"
			}
			]
		},
		{
			"name":"tRNA transport factors",
			"children":[
			{
				"name":"tRNA export factors"
			}
			]
		},
		{
			"name":"Aminoacyl-tRNA synthetases (AARSs)",
			"children":[
			{
				"name":"Multi-aminoacyl-tRNA synthetase complex (MSC)",
				"children":[
				{
					"name":"122556520 lars1b; leucine--tRNA ligase, cytoplasmic\tK01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]"
				},
				{
					"name":"122564532 lars2; probable leucine--tRNA ligase, mitochondrial isoform X1\tK01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]"
				},
				{
					"name":"122554758 pars2; probable proline--tRNA ligase, mitochondrial\tK01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]"
				}
				]
			},
			{
				"name":"Other AARSs",
				"children":[
				{
					"name":"122559568 yars2; tyrosine--tRNA ligase, mitochondrial\tK01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]"
				},
				{
					"name":"122563635 yars1; tyrosine--tRNA ligase, cytoplasmic\tK01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]"
				},
				{
					"name":"122553520 tryptophan--tRNA ligase, cytoplasmic\tK01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]"
				},
				{
					"name":"122555202 wars2; tryptophan--tRNA ligase, mitochondrial\tK01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]"
				},
				{
					"name":"122542508 threonine--tRNA ligase 1, cytoplasmic-like\tK01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]"
				},
				{
					"name":"122549017 tars1; threonine--tRNA ligase 1, cytoplasmic\tK01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]"
				},
				{
					"name":"122552806 iars2; isoleucine--tRNA ligase, mitochondrial\tK01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]"
				},
				{
					"name":"122558934 iars1; isoleucine--tRNA ligase, cytoplasmic\tK01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]"
				},
				{
					"name":"122558297 kars1; lysine--tRNA ligase isoform X1\tK04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]"
				},
				{
					"name":"122548560 aars2; alanine--tRNA ligase, mitochondrial isoform X1\tK01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]"
				},
				{
					"name":"122558586 aars1; alanine--tRNA ligase, cytoplasmic\tK01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]"
				},
				{
					"name":"122548333 vars1; valine--tRNA ligase isoform X1\tK01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]"
				},
				{
					"name":"122557226 mars2; methionine--tRNA ligase, mitochondrial\tK01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]"
				},
				{
					"name":"122542687 sars2; serine--tRNA ligase, mitochondrial\tK01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]"
				},
				{
					"name":"122563191 sars1; serine--tRNA ligase, cytoplasmic\tK01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]"
				},
				{
					"name":"122554636 dars2; aspartate--tRNA ligase, mitochondrial isoform X1\tK01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]"
				},
				{
					"name":"122551033 cars2; probable cysteine--tRNA ligase, mitochondrial\tK01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]"
				},
				{
					"name":"122560720 ears2; probable glutamate--tRNA ligase, mitochondrial\tK01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]"
				},
				{
					"name":"122559267 qars1; glutamine--tRNA ligase\tK01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18]"
				},
				{
					"name":"122548358 rars2; probable arginine--tRNA ligase, mitochondrial isoform X1\tK01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]"
				},
				{
					"name":"122556532 rars1; arginine--tRNA ligase, cytoplasmic isoform X1\tK01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]"
				},
				{
					"name":"122552231 farsa; phenylalanine--tRNA ligase alpha subunit\tK01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]"
				},
				{
					"name":"122564508 fars2; phenylalanine--tRNA ligase, mitochondrial isoform X1\tK01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]"
				},
				{
					"name":"122555850 farsb; phenylalanine--tRNA ligase beta subunit\tK01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]"
				},
				{
					"name":"122556433 hars; histidine--tRNA ligase isoform X1\tK01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]"
				},
				{
					"name":"122540371 nars1; asparagine--tRNA ligase, cytoplasmic\tK01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]"
				},
				{
					"name":"122550626 nars2; probable asparagine--tRNA ligase, mitochondrial isoform X1\tK01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]"
				}
				]
			},
			{
				"name":"Trans-editing factors",
				"children":[
				{
					"name":"122553049 dtd1; D-aminoacyl-tRNA deacylase 1\tK07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]"
				},
				{
					"name":"122553766 dtd2; D-aminoacyl-tRNA deacylase 2\tK07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]"
				},
				{
					"name":"122539871 aarsd1; alanyl-tRNA editing protein Aarsd1\tK07050 AARSD1; misacylated tRNA(Ala) deacylase [EC:3.1.1.-]"
				}
				]
			}
			]
		},
		{
			"name":"tRNA modification factors",
			"children":[
			{
				"name":"Deaminases"
			},
			{
				"name":"Dihydorouridine synthases"
			},
			{
				"name":"Methylthiotransferases",
				"children":[
				{
					"name":"122560019 cdk5rap1; CDK5 regulatory subunit-associated protein 1\tK06168 CDK5RAP1; tRNA-2-methylthio-N6-dimethylallyladenosine synthase [EC:2.8.4.3]"
				},
				{
					"name":"122564268 cdkal1; threonylcarbamoyladenosine tRNA methylthiotransferase\tK15865 CDKAL1; threonylcarbamoyladenosine tRNA methylthiotransferase [EC:2.8.4.5]"
				}
				]
			},
			{
				"name":"Methyltransferases",
				"children":[
				{
					"name":"122543276 mettl1; tRNA (guanine-N(7)-)-methyltransferase isoform X1\tK03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33]"
				},
				{
					"name":"122554633 gtpbp3; tRNA modification GTPase GTPBP3, mitochondrial\tK03650 mnmE; tRNA modification GTPase [EC:3.6.-.-]"
				},
				{
					"name":"122563373 trmo; tRNA (adenine(37)-N6)-methyltransferase\tK22900 TRMO; tRNA (adenine37-N6)-methyltransferase [EC:2.1.1.-]"
				}
				]
			},
			{
				"name":"Psudouridine synthases",
				"children":[
				{
					"name":"122562505 pus1; tRNA pseudouridine synthase A\tK06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]"
				},
				{
					"name":"122561215 trub1; probable tRNA pseudouridine synthase 1 isoform X1\tK03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]"
				},
				{
					"name":"122559511 pus7l; pseudouridylate synthase 7 homolog-like protein isoform X1\tK06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]"
				},
				{
					"name":"122561759 pus7; pseudouridylate synthase 7 homolog isoform X1\tK06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]"
				}
				]
			},
			{
				"name":"Thiolation factors",
				"children":[
				{
					"name":"122548301 nfs1; cysteine desulfurase, mitochondrial\tK04487 iscS; cysteine desulfurase [EC:2.8.1.7]"
				}
				]
			},
			{
				"name":"KEOPS\/EKC complex",
				"children":[
				{
					"name":"122560250 tp53rk; EKC\/KEOPS complex subunit TP53RK\tK08851 TP53RK; TP53 regulating kinase and related kinases [EC:2.7.11.1]"
				},
				{
					"name":"122551245 osgepl1; probable tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial isoform X1\tK01409 OSGEP; N6-L-threonylcarbamoyladenine synthase [EC:2.3.1.234]"
				}
				]
			},
			{
				"name":"Other tRNA modification factors",
				"children":[
				{
					"name":"122563756 trit1; tRNA dimethylallyltransferase isoform X1\tK00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]"
				},
				{
					"name":"122562021 pts; 6-pyruvoyl tetrahydrobiopterin synthase isoform X1\tK01737 queD; 6-pyruvoyltetrahydropterin\/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50]"
				},
				{
					"name":"122561871 sephs1; selenide, water dikinase 1\tK01008 selD; selenide, water dikinase [EC:2.7.9.3]"
				},
				{
					"name":"122563393 yrdc; yrdC domain-containing protein, mitochondrial\tK07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]"
				}
				]
			}
			]
		},
		{
			"name":"tRNA degradation factors",
			"children":[
			{
				"name":"122552884 polyribonucleotide nucleotidyltransferase 1, mitochondrial\tK00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]"
			},
			{
				"name":"122540914 interferon-stimulated gene 20 kDa protein-like isoform X1\tK12579 ISG20; interferon-stimulated gene 20 kDa protein [EC:3.1.13.1]"
			}
			]
		}
		]
	}
	]
}