{
	"name":"cpoc04121",
	"children":[
	{
		"name":"Ubiquitins and ubiquitin-like proteins",
		"children":[
		{
			"name":"Ubiquitins",
			"children":[
			{
				"name":"100286786 Ubc; polyubiquitin-B\tK08770 UBB_C; ubiquitin B\/C"
			},
			{
				"name":"100722422 Ubb; polyubiquitin-B\tK08770 UBB_C; ubiquitin B\/C"
			},
			{
				"name":"100719482 Uba52; ubiquitin-60S ribosomal protein L40\tK02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e"
			},
			{
				"name":"100286787 Rps27a; ubiquitin-40S ribosomal protein S27a\tK02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae"
			}
			]
		},
		{
			"name":"Ubiquitin-like proteins (UBLs)",
			"children":[
			{
				"name":"100715833 Ubd; LOW QUALITY PROTEIN: ubiquitin D\tK12157 UBD; ubiquitin D"
			},
			{
				"name":"100730485 Nedd8; NEDD8\tK12158 NEDD8; ubiquitin-like protein Nedd8"
			},
			{
				"name":"100726002 Fau; ubiquitin-like protein fubi and ribosomal protein S30\tK02983 RP-S30e; small subunit ribosomal protein S30e"
			},
			{
				"name":"100731608 Isg15; ubiquitin-like protein ISG15\tK12159 ISG15; ubiquitin cross-reactive protein"
			},
			{
				"name":"100718179 Sumo3; small ubiquitin-related modifier 3\tK12160 SUMO; small ubiquitin-related modifier"
			},
			{
				"name":"100719994 Sumo1; small ubiquitin-related modifier 1\tK12160 SUMO; small ubiquitin-related modifier"
			},
			{
				"name":"100727754 Sumo2; small ubiquitin-related modifier 2\tK12160 SUMO; small ubiquitin-related modifier"
			},
			{
				"name":"101788353 small ubiquitin-related modifier 2-like\tK12160 SUMO; small ubiquitin-related modifier"
			},
			{
				"name":"100135524 Gabarapl1; gamma-aminobutyric acid receptor-associated protein-like 1\tK08341 GABARAP; GABA(A) receptor-associated protein"
			},
			{
				"name":"100726484 Gabarapl2; gamma-aminobutyric acid receptor-associated protein-like 2 isoform X2\tK08341 GABARAP; GABA(A) receptor-associated protein"
			},
			{
				"name":"100719707 Atg12; ubiquitin-like protein ATG12 isoform X1\tK08336 ATG12; ubiquitin-like protein ATG12"
			},
			{
				"name":"100714855 Urm1; ubiquitin-related modifier 1 isoform X2\tK12161 URM1; ubiquitin related modifier 1"
			},
			{
				"name":"101788383 Ufm1; ubiquitin-fold modifier 1\tK12162 UFM1; ubiquitin-fold modifier 1"
			},
			{
				"name":"100732879 Ubl3; ubiquitin-like protein 3\tK28515 UBL3; membrane-anchored ubiquitin-fold protein"
			},
			{
				"name":"100717811 Zfand4; AN1-type zinc finger protein 4\tK12163 ZFAND4; AN1-type zinc finger protein 4"
			}
			]
		}
		]
	},
	{
		"name":"Ubiquitin-activating enzymes (E1)",
		"children":[
		{
			"name":"Ubiquitin activating enzyme",
			"children":[
			{
				"name":"100726349 Uba1; ubiquitin-like modifier-activating enzyme 1\tK03178 UBE1; ubiquitin-activating enzyme E1 [EC:6.2.1.45]"
			}
			]
		},
		{
			"name":"UBL-activating enzymes",
			"children":[
			{
				"name":"100718649 Sae1; SUMO-activating enzyme subunit 1\tK10684 UBLE1A; ubiquitin-like 1-activating enzyme E1 A [EC:6.2.1.45]"
			},
			{
				"name":"100719212 Uba2; SUMO-activating enzyme subunit 2\tK10685 UBLE1B; ubiquitin-like 1-activating enzyme E1 B [EC:6.2.1.45]"
			},
			{
				"name":"100720892 Uba3; NEDD8-activating enzyme E1 catalytic subunit\tK10686 UBA3; NEDD8-activating enzyme E1 [EC:6.2.1.64]"
			},
			{
				"name":"100725751 Nae1; NEDD8-activating enzyme E1 regulatory subunit\tK04532 NAE1; NEDD8-activating enzyme E1 regulatory subunit"
			},
			{
				"name":"100729606 Mocs3; adenylyltransferase and sulfurtransferase MOCS3\tK11996 MOCS3; adenylyltransferase and sulfurtransferase [EC:2.7.7.80 2.8.1.11]"
			},
			{
				"name":"100726590 Uba5; ubiquitin-like modifier-activating enzyme 5\tK12164 UBA5; ubiquitin-like modifier-activating enzyme 5"
			},
			{
				"name":"100731595 Uba7; ubiquitin-like modifier-activating enzyme 7 isoform X1\tK10698 UBE1L; ubiquitin-activating enzyme E1-like [EC:6.2.1.45]"
			},
			{
				"name":"100720312 Uba6; ubiquitin-like modifier-activating enzyme 6\tK10699 UBE1L2; ubiquitin-activating enzyme E1-like protein 2 [EC:6.2.1.45]"
			},
			{
				"name":"100730244 Atg7; ubiquitin-like modifier-activating enzyme ATG7 isoform X1\tK08337 ATG7; ubiquitin-like modifier-activating enzyme ATG7"
			}
			]
		}
		]
	},
	{
		"name":"Ubiquitin-conjugating enzymes (E2)",
		"children":[
		{
			"name":"Ubiquitin-conjugating enzymes",
			"children":[
			{
				"name":"100715223 Ube2a; ubiquitin-conjugating enzyme E2 A\tK10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]"
			},
			{
				"name":"100713340 Ube2b; ubiquitin-conjugating enzyme E2 B\tK10574 UBE2B; ubiquitin-conjugating enzyme E2 B [EC:2.3.2.23]"
			},
			{
				"name":"100718665 Ube2c; ubiquitin-conjugating enzyme E2 C\tK06688 UBE2C; ubiquitin-conjugating enzyme E2 C [EC:2.3.2.23]"
			},
			{
				"name":"100719789 ubiquitin-conjugating enzyme E2 D2-like\tK06689 UBE2D; ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]"
			},
			{
				"name":"100720620 ubiquitin-conjugating enzyme E2 D2-like\tK06689 UBE2D; ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]"
			},
			{
				"name":"100729437 Ube2d4; ubiquitin-conjugating enzyme E2 D4 isoform X1\tK06689 UBE2D; ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]"
			},
			{
				"name":"100730907 Ube2d3; ubiquitin-conjugating enzyme E2 D3\tK06689 UBE2D; ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]"
			},
			{
				"name":"100732779 Ube2d2; ubiquitin-conjugating enzyme E2 D2\tK06689 UBE2D; ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]"
			},
			{
				"name":"100734273 Ube2d1; ubiquitin-conjugating enzyme E2 D1\tK06689 UBE2D; ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]"
			},
			{
				"name":"100718900 Ube2e3; ubiquitin-conjugating enzyme E2 E3\tK20217 UBE2E; ubiquitin-conjugating enzyme E2 E [EC:2.3.2.23]"
			},
			{
				"name":"100722231 Ube2e1; ubiquitin-conjugating enzyme E2 E1 isoform X1\tK20217 UBE2E; ubiquitin-conjugating enzyme E2 E [EC:2.3.2.23]"
			},
			{
				"name":"100722511 ubiquitin-conjugating enzyme E2 E2 isoform X1\tK20217 UBE2E; ubiquitin-conjugating enzyme E2 E [EC:2.3.2.23]"
			},
			{
				"name":"100729908 Ube2g1; ubiquitin-conjugating enzyme E2 G1\tK10575 UBE2G1; ubiquitin-conjugating enzyme E2 G1 [EC:2.3.2.23]"
			},
			{
				"name":"100718459 Ube2g2; ubiquitin-conjugating enzyme E2 G2 isoform X1\tK04555 UBE2G2; ubiquitin-conjugating enzyme E2 G2 [EC:2.3.2.23]"
			},
			{
				"name":"100721172 Ube2h; ubiquitin-conjugating enzyme E2 H\tK10576 UBE2H; ubiquitin-conjugating enzyme E2 H [EC:2.3.2.23]"
			},
			{
				"name":"100717486 ubiquitin-conjugating enzyme E2 J1\tK10578 UBE2J1; ubiquitin-conjugating enzyme E2 J1 [EC:2.3.2.23]"
			},
			{
				"name":"100729250 Ube2j1; ubiquitin-conjugating enzyme E2 J1\tK10578 UBE2J1; ubiquitin-conjugating enzyme E2 J1 [EC:2.3.2.23]"
			},
			{
				"name":"100730229 Ube2j2; ubiquitin-conjugating enzyme E2 J2 isoform X1\tK04554 UBE2J2; ubiquitin-conjugating enzyme E2 J2 [EC:2.3.2.23]"
			},
			{
				"name":"100716372 Ube2k; ubiquitin-conjugating enzyme E2 K\tK04649 UBE2K; ubiquitin-conjugating enzyme (huntingtin interacting protein 2) [EC:2.3.2.23]"
			},
			{
				"name":"100714064 Ube2l3; ubiquitin-conjugating enzyme E2 L3\tK04552 UBE2L3; ubiquitin-conjugating enzyme E2 L3 [EC:2.3.2.23]"
			},
			{
				"name":"100722134 Ube2l6; ubiquitin\/ISG15-conjugating enzyme E2 L6\tK04553 UBE2L6; ubiquitin\/ISG15-conjugating enzyme E2 L6 [EC:2.3.2.23]"
			},
			{
				"name":"100726684 Ube2n; ubiquitin-conjugating enzyme E2 N\tK10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]"
			},
			{
				"name":"100727315 ubiquitin-conjugating enzyme E2 N\tK10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]"
			},
			{
				"name":"106026468 ubiquitin-conjugating enzyme E2 N-like\tK10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]"
			},
			{
				"name":"100723966 Ube2o; (E3-independent) E2 ubiquitin-conjugating enzyme isoform X2\tK10581 UBE2O; ubiquitin-conjugating enzyme E2 O [EC:2.3.2.24]"
			},
			{
				"name":"100721764 Ube2q2; ubiquitin-conjugating enzyme E2 Q2 isoform X2\tK10582 UBE2Q; ubiquitin-conjugating enzyme E2 Q [EC:2.3.2.23]"
			},
			{
				"name":"100732687 Ube2q1; ubiquitin-conjugating enzyme E2 Q1\tK10582 UBE2Q; ubiquitin-conjugating enzyme E2 Q [EC:2.3.2.23]"
			},
			{
				"name":"100735700 Ube2ql1; ubiquitin-conjugating enzyme E2Q-like protein 1\tK10582 UBE2Q; ubiquitin-conjugating enzyme E2 Q [EC:2.3.2.23]"
			},
			{
				"name":"100720432 Ube2r2; ubiquitin-conjugating enzyme E2 R2 isoform X1\tK02207 UBE2R; ubiquitin-conjugating enzyme E2 R [EC:2.3.2.23]"
			},
			{
				"name":"100723029 Cdc34; ubiquitin-conjugating enzyme E2 R1\tK02207 UBE2R; ubiquitin-conjugating enzyme E2 R [EC:2.3.2.23]"
			},
			{
				"name":"100734699 Ube2s; ubiquitin-conjugating enzyme E2 S\tK10583 UBE2S; ubiquitin-conjugating enzyme E2 S [EC:2.3.2.23]"
			},
			{
				"name":"100730758 Ube2t; ubiquitin-conjugating enzyme E2 T isoform X1\tK13960 UBE2T; ubiquitin-conjugating enzyme E2 T [EC:2.3.2.23]"
			},
			{
				"name":"100727733 Ube2u; ubiquitin-conjugating enzyme E2 U isoform X3\tK10584 UBE2U; ubiquitin-conjugating enzyme E2 U [EC:2.3.2.23]"
			},
			{
				"name":"100730250 Ube2w; ubiquitin-conjugating enzyme E2 W\tK10688 UBE2W; ubiquitin-conjugating enzyme E2 W [EC:2.3.2.23 2.3.2.25]"
			},
			{
				"name":"100718845 Ube2z; ubiquitin-conjugating enzyme E2 Z\tK10585 UBE2Z; ubiquitin-conjugating enzyme E2 Z [EC:2.3.2.23]"
			},
			{
				"name":"100735665 Birc6; baculoviral IAP repeat-containing protein 6\tK10586 BIRC6; baculoviral IAP repeat-containing protein 6 (apollon) [EC:2.3.2.23]"
			}
			]
		},
		{
			"name":"UBL-conjugating enzymes",
			"children":[
			{
				"name":"100722207 Ube2i; SUMO-conjugating enzyme UBC9\tK10577 UBE2I; ubiquitin-conjugating enzyme E2 I"
			},
			{
				"name":"100728726 Ube2f; NEDD8-conjugating enzyme UBE2F\tK10687 UBE2F; ubiquitin-conjugating enzyme E2 F [EC:2.3.2.34]"
			},
			{
				"name":"100716983 Ube2m; NEDD8-conjugating enzyme Ubc12\tK10579 UBE2M; ubiquitin-conjugating enzyme E2 M [EC:2.3.2.34]"
			},
			{
				"name":"100722134 Ube2l6; ubiquitin\/ISG15-conjugating enzyme E2 L6\tK04553 UBE2L6; ubiquitin\/ISG15-conjugating enzyme E2 L6 [EC:2.3.2.23]"
			},
			{
				"name":"100732478 Atg3; ubiquitin-like-conjugating enzyme ATG3\tK08343 ATG3; ubiquitin-like-conjugating enzyme ATG3"
			},
			{
				"name":"100728938 Atg10; ubiquitin-like-conjugating enzyme ATG10\tK17888 ATG10L; ubiquitin-like-conjugating enzyme ATG10"
			},
			{
				"name":"100735079 Ufc1; ubiquitin-fold modifier-conjugating enzyme 1\tK12165 UFC1; ufm1-conjugating enzyme 1"
			}
			]
		}
		]
	},
	{
		"name":"Ubiquitin ligases (E3)",
		"children":[
		{
			"name":"HECT type E3",
			"children":[
			{
				"name":"100730511 Ube3a; LOW QUALITY PROTEIN: ubiquitin-protein ligase E3A\tK10587 UBE3A; ubiquitin-protein ligase E3 A [EC:2.3.2.26]"
			},
			{
				"name":"100720918 Ube3b; ubiquitin-protein ligase E3B isoform X1\tK10588 UBE3B; ubiquitin-protein ligase E3 B [EC:2.3.2.26]"
			},
			{
				"name":"100723450 Ube3c; ubiquitin-protein ligase E3C\tK10589 UBE3C; ubiquitin-protein ligase E3 C [EC:2.3.2.26]"
			},
			{
				"name":"100730012 Ube3d; E3 ubiquitin-protein ligase E3D isoform X1\tK20803 UBE3D; ubiquitin-protein ligase E3 D [EC:2.3.2.26]"
			},
			{
				"name":"100715134 Smurf1; E3 ubiquitin-protein ligase SMURF1 isoform X1\tK04678 SMURF; E3 ubiquitin ligase SMURF1\/2 [EC:2.3.2.26]"
			},
			{
				"name":"100734512 Smurf2; E3 ubiquitin-protein ligase SMURF2\tK04678 SMURF; E3 ubiquitin ligase SMURF1\/2 [EC:2.3.2.26]"
			},
			{
				"name":"100724288 Itch; E3 ubiquitin-protein ligase Itchy homolog isoform X1\tK05632 ITCH; E3 ubiquitin-protein ligase Itchy [EC:2.3.2.26]"
			},
			{
				"name":"100715948 Wwp1; NEDD4-like E3 ubiquitin-protein ligase WWP1\tK05633 WWP1; NEDD4-like E3 ubiquitin-protein ligase WWP1 [EC:2.3.2.26]"
			},
			{
				"name":"100721341 Wwp2; NEDD4-like E3 ubiquitin-protein ligase WWP2 isoform X1\tK05630 WWP2; NEDD4-like E3 ubiquitin-protein ligase WWP2 [EC:2.3.2.26]"
			},
			{
				"name":"100729386 Trip12; E3 ubiquitin-protein ligase TRIP12\tK10590 TRIP12; E3 ubiquitin-protein ligase TRIP12 [EC:2.3.2.26]"
			},
			{
				"name":"100722637 Nedd4; E3 ubiquitin-protein ligase NEDD4 isoform X1\tK10591 NEDD4; E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26]"
			},
			{
				"name":"100301562 Nedd4l; E3 ubiquitin-protein ligase NEDD4-like isoform X6\tK13305 NEDD4L; E3 ubiquitin-protein ligase NEDD4-like [EC:2.3.2.26]"
			},
			{
				"name":"100722589 Huwe1; E3 ubiquitin-protein ligase HUWE1\tK10592 HUWE1; E3 ubiquitin-protein ligase HUWE1 [EC:2.3.2.26]"
			},
			{
				"name":"100733892 Arel1; apoptosis-resistant E3 ubiquitin protein ligase 1 isoform X2\tK22370 AREL1; apoptosis-resistant E3 ubiquitin protein ligase 1 [EC:2.3.2.26]"
			},
			{
				"name":"100720846 Ubr5; LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase UBR5\tK10593 EDD1; E3 ubiquitin-protein ligase EDD1 [EC:2.3.2.26]"
			},
			{
				"name":"100713535 G2e3; G2\/M phase-specific E3 ubiquitin-protein ligase\tK22371 G2H3; G2\/M phase-specific E3 ubiquitin-protein ligase [EC:2.3.2.26]"
			},
			{
				"name":"100717224 Herc1; LOW QUALITY PROTEIN: probable E3 ubiquitin-protein ligase HERC1\tK10594 HERC1; E3 ubiquitin-protein ligase HERC1 [EC:2.3.2.26]"
			},
			{
				"name":"100731329 E3 ubiquitin-protein ligase HERC2\tK10595 HERC2; E3 ubiquitin-protein ligase HERC2 [EC:2.3.2.26]"
			},
			{
				"name":"100724559 Herc3; probable E3 ubiquitin-protein ligase HERC3 isoform X1\tK10614 HERC3; E3 ubiquitin-protein ligase HERC3 [EC:2.3.2.26]"
			},
			{
				"name":"100717289 Herc4; probable E3 ubiquitin-protein ligase HERC4\tK10615 HERC4; E3 ubiquitin-protein ligase HERC4 [EC:2.3.2.26]"
			},
			{
				"name":"100733867 Hace1; E3 ubiquitin-protein ligase HACE1 isoform X1\tK12166 HACE1; E3 ubiquitin-protein ligase HACE1 [EC:2.3.2.26]"
			},
			{
				"name":"100721705 Hecw1; E3 ubiquitin-protein ligase HECW1 isoform X1\tK12167 HECW1; E3 ubiquitin-protein ligase HECW1 [EC:2.3.2.26]"
			},
			{
				"name":"100724624 Hecw2; E3 ubiquitin-protein ligase HECW2 isoform X2\tK12168 HECW2; E3 ubiquitin-protein ligase HECW2 [EC:2.3.2.26]"
			},
			{
				"name":"100733097 Hectd1; LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase HECTD1\tK12231 HECTD1; E3 ubiquitin-protein ligase HECTD1 [EC:2.3.2.26]"
			},
			{
				"name":"100713517 Hectd2; probable E3 ubiquitin-protein ligase HECTD2\tK12232 HECTD2; E3 ubiquitin-protein ligase HECTD2 [EC:2.3.2.26]"
			},
			{
				"name":"100723587 Hectd3; E3 ubiquitin-protein ligase HECTD3\tK12233 HECTD3; E3 ubiquitin-protein ligase HECTD3 [EC:2.3.2.26]"
			},
			{
				"name":"100721575 Hectd4; probable E3 ubiquitin-protein ligase HECTD4\tK17849 HECTD4; E3 ubiquitin-protein ligase HECTD4 [EC:2.3.2.26]"
			},
			{
				"name":"HECT type E3 associated proteins",
				"children":[
				{
					"name":"100724605 Ndfip2; NEDD4 family-interacting protein 2\tK25839 NDFIP; NEDD4 family-interacting protein"
				},
				{
					"name":"100726594 Ndfip1; NEDD4 family-interacting protein 1\tK25839 NDFIP; NEDD4 family-interacting protein"
				},
				{
					"name":"100724609 N4bp3; NEDD4-binding protein 3\tK26473 N4BP3; NEDD4-binding protein 3"
				},
				{
					"name":"100724977 CUNH16orf72; UPF0472 protein C16orf72 homolog\tK27699 HAPSTR1; HUWE1-associated protein modifying stress responses 1"
				},
				{
					"name":"100714827 UPF0472 protein C16orf72 homolog\tK27700 HAPSTR2; HUWE1-associated protein modifying stress responses 2"
				}
				]
			}
			]
		},
		{
			"name":"U-box type E3",
			"children":[
			{
				"name":"100726213 Ube4a; ubiquitin conjugation factor E4 A\tK10596 UBE4A; ubiquitin conjugation factor E4 A [EC:2.3.2.27]"
			},
			{
				"name":"100727679 Ube4b; ubiquitin conjugation factor E4 B isoform X1\tK10597 UBE4B; ubiquitin conjugation factor E4 B [EC:2.3.2.27]"
			},
			{
				"name":"100717320 Stub1; E3 ubiquitin-protein ligase CHIP isoform X1\tK09561 STUB1; STIP1 homology and U-box containing protein 1 [EC:2.3.2.27]"
			},
			{
				"name":"100734019 Ppil2; peptidyl-prolyl cis-trans isomerase-like 2\tK10598 PPIL2; peptidyl-prolyl cis-trans isomerase-like 2 [EC:5.2.1.8]"
			},
			{
				"name":"100722057 Prpf19; pre-mRNA-processing factor 19\tK10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]"
			},
			{
				"name":"100718260 Rbbp6; LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase RBBP6\tK10624 RBBP6; E3 ubiquitin-protein ligase RBBP6 [EC:2.3.2.27]"
			},
			{
				"name":"100719722 Ubox5; RING finger protein 37 isoform X1\tK10600 UBOX5; U-box domain-containing protein 5 [EC:2.3.2.27]"
			}
			]
		},
		{
			"name":"Single Ring-finger type E3",
			"children":[
			{
				"name":"BRE1 proteins",
				"children":[
				{
					"name":"100714613 Rnf40; E3 ubiquitin-protein ligase BRE1B\tK10696 BRE1; E3 ubiquitin-protein ligase BRE1 [EC:2.3.2.27]"
				},
				{
					"name":"100717191 Rnf20; LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase BRE1A\tK10696 BRE1; E3 ubiquitin-protein ligase BRE1 [EC:2.3.2.27]"
				}
				]
			},
			{
				"name":"CBL proteins",
				"children":[
				{
					"name":"100725041 Cbl; E3 ubiquitin-protein ligase CBL\tK04707 CBL; E3 ubiquitin-protein ligase CBL [EC:2.3.2.27]"
				},
				{
					"name":"100718857 Cblb; LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase CBL-B\tK22517 CBLB; E3 ubiquitin-protein ligase CBL-B [EC:2.3.2.27]"
				},
				{
					"name":"100718565 Cblc; E3 ubiquitin-protein ligase CBL-C\tK22518 CBLC; E3 ubiquitin-protein ligase CBL-C [EC:2.3.2.27]"
				}
				]
			},
			{
				"name":"SINA (Seven in absentia) proteins",
				"children":[
				{
					"name":"100722988 Siah1; E3 ubiquitin-protein ligase SIAH1\tK04506 SIAH1; E3 ubiquitin-protein ligase SIAH1 [EC:2.3.2.27]"
				},
				{
					"name":"100718979 Siah2; E3 ubiquitin-protein ligase SIAH2\tK08742 SIAH2; E3 ubiquitin-protein ligase SIAH2 [EC:2.3.2.27]"
				}
				]
			},
			{
				"name":"Ligand of Numb proteins",
				"children":[
				{
					"name":"100719913 Lnx2; ligand of Numb protein X 2\tK10692 LNX1_2; ligand of Numb protein X 1\/2 [EC:2.3.2.27]"
				},
				{
					"name":"100725036 Lnx1; E3 ubiquitin-protein ligase LNX isoform X1\tK10692 LNX1_2; ligand of Numb protein X 1\/2 [EC:2.3.2.27]"
				},
				{
					"name":"100717120 Pdzrn4; PDZ domain-containing RING finger protein 4\tK15682 PDZRN3_4; ligand of Numb protein X 3\/4 [EC:2.3.2.27]"
				},
				{
					"name":"100733896 Pdzrn3; LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase PDZRN3\tK15682 PDZRN3_4; ligand of Numb protein X 3\/4 [EC:2.3.2.27]"
				}
				]
			},
			{
				"name":"March proteins",
				"children":[
				{
					"name":"100718377 March8; E3 ubiquitin-protein ligase MARCH8 isoform X5\tK10656 MARCH1_8; E3 ubiquitin-protein ligase MARCH1\/8 [EC:2.3.2.27]"
				},
				{
					"name":"100722498 March1; E3 ubiquitin-protein ligase MARCH1 isoform X1\tK10656 MARCH1_8; E3 ubiquitin-protein ligase MARCH1\/8 [EC:2.3.2.27]"
				},
				{
					"name":"100731413 March3; E3 ubiquitin-protein ligase MARCH3\tK10657 MARCH2_3; E3 ubiquitin-protein ligase MARCH2\/3 [EC:2.3.2.27]"
				},
				{
					"name":"100733733 March2; E3 ubiquitin-protein ligase MARCH2 isoform X1\tK10657 MARCH2_3; E3 ubiquitin-protein ligase MARCH2\/3 [EC:2.3.2.27]"
				},
				{
					"name":"100714424 March9; E3 ubiquitin-protein ligase MARCH9\tK10659 MARCH4_9_11; E3 ubiquitin-protein ligase MARCH4\/9\/11 [EC:2.3.2.27]"
				},
				{
					"name":"100725253 March4; E3 ubiquitin-protein ligase MARCH4\tK10659 MARCH4_9_11; E3 ubiquitin-protein ligase MARCH4\/9\/11 [EC:2.3.2.27]"
				},
				{
					"name":"100723777 March5; E3 ubiquitin-protein ligase MARCH5\tK10660 MARCH5; E3 ubiquitin-protein ligase MARCH5 [EC:2.3.2.27]"
				},
				{
					"name":"100716981 March6; E3 ubiquitin-protein ligase MARCH6\tK10661 MARCH6; E3 ubiquitin-protein ligase MARCH6 [EC:2.3.2.27]"
				},
				{
					"name":"100723317 March7; E3 ubiquitin-protein ligase MARCH7\tK10662 MARCH7; E3 ubiquitin-protein ligase MARCH7 [EC:2.3.2.27]"
				},
				{
					"name":"100714929 March10; LOW QUALITY PROTEIN: probable E3 ubiquitin-protein ligase MARCH10\tK10665 MARCH10; E3 ubiquitin-protein ligase MARCH10 [EC:2.3.2.27]"
				}
				]
			},
			{
				"name":"MDM2\/MDM4 proteins",
				"children":[
				{
					"name":"100724684 Mdm2; E3 ubiquitin-protein ligase Mdm2 isoform X1\tK06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]"
				},
				{
					"name":"100719525 Mdm4; protein Mdm4 isoform X1\tK10127 MDM4; protein Mdm4"
				}
				]
			},
			{
				"name":"NFX1 proteins",
				"children":[
				{
					"name":"100723545 Nfx1; transcriptional repressor NF-X1 isoform X2\tK12236 NFX1; transcriptional repressor NF-X1"
				},
				{
					"name":"100720623 Nfxl1; NF-X1-type zinc finger protein NFXL1\tK15683 NFXL1; NF-X1-type zinc finger protein NFXL1"
				}
				]
			},
			{
				"name":"Pellino proteins",
				"children":[
				{
					"name":"100716351 Peli3; E3 ubiquitin-protein ligase pellino homolog 3 isoform X2\tK11964 PELI; pellino [EC:2.3.2.27]"
				},
				{
					"name":"100730342 Peli1; E3 ubiquitin-protein ligase pellino homolog 1\tK11964 PELI; pellino [EC:2.3.2.27]"
				},
				{
					"name":"100731206 Peli2; E3 ubiquitin-protein ligase pellino homolog 2\tK11964 PELI; pellino [EC:2.3.2.27]"
				}
				]
			},
			{
				"name":"Peripheral membrane proteins",
				"children":[
				{
					"name":"100725688 Pex10; peroxisome biogenesis factor 10 isoform X1\tK13346 PEX10; peroxin-10 [EC:2.3.2.27]"
				},
				{
					"name":"100714850 Pex12; peroxisome assembly protein 12\tK13345 PEX12; peroxin-12"
				},
				{
					"name":"100735251 Pex2; peroxisome biogenesis factor 2\tK06664 PEX2; peroxin-2 [EC:2.3.2.27 2.3.2.36]"
				}
				]
			},
			{
				"name":"RBR proteins",
				"children":[
				{
					"name":"100724550 Prkn; E3 ubiquitin-protein ligase parkin\tK04556 PARK2; parkin [EC:2.3.2.31]"
				},
				{
					"name":"100731492 Ankib1; ankyrin repeat and IBR domain-containing protein 1 isoform X2\tK11967 ANKIB1; ankyrin repeat and IBR domain-containing protein 1 [EC:2.3.2.31]"
				},
				{
					"name":"100713227 Arih1; E3 ubiquitin-protein ligase ARIH1\tK11968 ARIH1; ariadne-1 [EC:2.3.2.31]"
				},
				{
					"name":"100729753 Arih2; E3 ubiquitin-protein ligase ARIH2 isoform X1\tK11969 ARIH2; ariadne-2 [EC:2.3.2.31]"
				},
				{
					"name":"100734748 Rbck1; ranBP-type and C3HC4-type zinc finger-containing protein 1\tK10630 RBCK1; RanBP-type and C3HC4-type zinc finger-containing protein 1 [EC:2.3.2.31]"
				},
				{
					"name":"100725874 Rnf14; LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase RNF14\tK11971 RNF14; E3 ubiquitin-protein ligase RNF14 [EC:2.3.2.31]"
				},
				{
					"name":"100728019 Rnf19a; E3 ubiquitin-protein ligase RNF19A\tK11972 RNF19A; E3 ubiquitin-protein ligase RNF19A [EC:2.3.2.31]"
				},
				{
					"name":"100726294 Rnf19b; LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase RNF19B\tK11973 RNF19B; E3 ubiquitin-protein ligase RNF19B [EC:2.3.2.31]"
				},
				{
					"name":"100733433 Rnf31; E3 ubiquitin-protein ligase RNF31 isoform X1\tK11974 RNF31; E3 ubiquitin-protein ligase RNF31 [EC:2.3.2.31]"
				},
				{
					"name":"100715693 Rffl; E3 ubiquitin-protein ligase rififylin isoform X2\tK20804 RNF34; E3 ubiquitin-protein ligase RNF34 [EC:2.3.2.31]"
				},
				{
					"name":"100715758 Rnf34; E3 ubiquitin-protein ligase RNF34\tK20804 RNF34; E3 ubiquitin-protein ligase RNF34 [EC:2.3.2.31]"
				},
				{
					"name":"100722712 Rnf144b; E3 ubiquitin-protein ligase RNF144B\tK11975 RNF144; E3 ubiquitin-protein ligase RNF144 [EC:2.3.2.31]"
				},
				{
					"name":"100730159 Rnf144a; E3 ubiquitin-protein ligase RNF144A\tK11975 RNF144; E3 ubiquitin-protein ligase RNF144 [EC:2.3.2.31]"
				},
				{
					"name":"100723206 Rnf168; E3 ubiquitin-protein ligase RNF168\tK20779 RNF168; E3 ubiquitin-protein ligase RNF168 [EC:2.3.2.31]"
				},
				{
					"name":"100712887 Rnf169; E3 ubiquitin-protein ligase RNF169\tK20805 RNF169; E3 ubiquitin-protein ligase RNF169 [EC:2.3.2.31]"
				},
				{
					"name":"100722232 Rnf183; probable E3 ubiquitin-protein ligase RNF183\tK22157 RNF183; E3 ubiquitin-protein ligase RNF183 [EC:2.3.2.31]"
				},
				{
					"name":"100733973 Rnf216; E3 ubiquitin-protein ligase RNF216 isoform X1\tK11976 RNF216; E3 ubiquitin-protein ligase RNF216 [EC:2.3.2.31]"
				},
				{
					"name":"100726995 Rnf217; probable E3 ubiquitin-protein ligase RNF217\tK11977 RNF217; E3 ubiquitin-protein ligase RNF217 [EC:2.3.2.31]"
				}
				]
			},
			{
				"name":"TRAF proteins",
				"children":[
				{
					"name":"100733145 Traf2; TNF receptor-associated factor 2 isoform X2\tK03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]"
				},
				{
					"name":"100721722 Traf5; TNF receptor-associated factor 5 isoform X1\tK09849 TRAF5; TNF receptor-associated factor 5"
				},
				{
					"name":"100724447 Traf6; TNF receptor-associated factor 6\tK03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]"
				},
				{
					"name":"100733170 Traf7; E3 ubiquitin-protein ligase TRAF7 isoform X1\tK10646 TRAF7; E3 ubiquitin-protein ligase TRAF7 [EC:2.3.2.27]"
				}
				]
			},
			{
				"name":"TRIM\/RBCC proteins",
				"children":[
				{
					"name":"100719594 Mid2; probable E3 ubiquitin-protein ligase MID2 isoform X3\tK10647 TRIM1; midline 2 [EC:2.3.2.27]"
				},
				{
					"name":"100718148 Trim2; tripartite motif-containing protein 2 isoform X1\tK11997 TRIM2_3; tripartite motif-containing protein 2\/3"
				},
				{
					"name":"100734787 Trim3; tripartite motif-containing protein 3\tK11997 TRIM2_3; tripartite motif-containing protein 2\/3"
				},
				{
					"name":"100714924 tripartite motif-containing protein 12A-like\tK10648 TRIM5; tripartite motif-containing protein 5 [EC:2.3.2.27]"
				},
				{
					"name":"100715495 tripartite motif-containing protein 5-like\tK10648 TRIM5; tripartite motif-containing protein 5 [EC:2.3.2.27]"
				},
				{
					"name":"100716056 LOW QUALITY PROTEIN: tripartite motif-containing protein 12A-like\tK10648 TRIM5; tripartite motif-containing protein 5 [EC:2.3.2.27]"
				},
				{
					"name":"100715212 tripartite motif-containing protein 34\tK11999 TRIM6_22_34; tripartite motif-containing protein 6\/22\/34"
				},
				{
					"name":"100716342 Trim6; tripartite motif-containing protein 6\tK11999 TRIM6_22_34; tripartite motif-containing protein 6\/22\/34"
				},
				{
					"name":"100719333 Trim7; E3 ubiquitin-protein ligase TRIM7\tK12000 TRIM7; tripartite motif-containing protein 7"
				},
				{
					"name":"100726575 Trim67; tripartite motif-containing protein 67\tK10649 TRIM9_67; tripartite motif-containing protein 9\/67"
				},
				{
					"name":"100729922 Trim9; E3 ubiquitin-protein ligase TRIM9 isoform X8\tK10649 TRIM9_67; tripartite motif-containing protein 9\/67"
				},
				{
					"name":"111753274 Trim10; tripartite motif-containing protein 10\tK12002 TRIM10; tripartite motif-containing protein 10"
				},
				{
					"name":"100712952 Trim11; E3 ubiquitin-protein ligase TRIM11 isoform X2\tK10650 TRIM11; tripartite motif-containing protein 11 [EC:2.3.2.27]"
				},
				{
					"name":"100720557 Trim13; E3 ubiquitin-protein ligase TRIM13 isoform X1\tK12003 TRIM13; tripartite motif-containing protein 13 [EC:2.3.2.27]"
				},
				{
					"name":"100713564 Trim14; LOW QUALITY PROTEIN: tripartite motif-containing protein 14\tK12004 TRIM14; tripartite motif-containing protein 14"
				},
				{
					"name":"100723249 Trim16; tripartite motif-containing protein 16\tK12006 TRIM16; tripartite motif-containing protein 16 [EC:2.3.2.27]"
				},
				{
					"name":"100719636 Trim17; E3 ubiquitin-protein ligase TRIM17\tK12007 TRIM17; tripartite motif-containing protein 17 [EC:2.3.2.27]"
				},
				{
					"name":"100716416 Mid1; E3 ubiquitin-protein ligase Midline-1 isoform X1\tK08285 TRIM18; midline 1 [EC:2.3.2.27]"
				},
				{
					"name":"100729320 Trim21; E3 ubiquitin-protein ligase TRIM21\tK10651 TRIM21; tripartite motif-containing protein 21 [EC:2.3.2.27]"
				},
				{
					"name":"100727720 Trim23; E3 ubiquitin-protein ligase TRIM23 isoform X1\tK07963 TRIM23; tripartite motif-containing protein 23 [EC:2.3.2.27]"
				},
				{
					"name":"100721356 Trim24; transcription intermediary factor 1-alpha\tK08881 TRIM24; tripartite motif-containing protein 24 [EC:2.3.2.27]"
				},
				{
					"name":"100720319 E3 ubiquitin\/ISG15 ligase TRIM25-like\tK10652 TRIM25; tripartite motif-containing protein 25 [EC:2.3.2.27]"
				},
				{
					"name":"100727761 LOW QUALITY PROTEIN: E3 ubiquitin\/ISG15 ligase TRIM25\tK10652 TRIM25; tripartite motif-containing protein 25 [EC:2.3.2.27]"
				},
				{
					"name":"100734574 tripartite motif-containing protein 26-like isoform X2\tK12008 TRIM26; tripartite motif-containing protein 26"
				},
				{
					"name":"100732725 Trim27; LOW QUALITY PROTEIN: zinc finger protein RFP\tK12009 TRIM27; tripartite motif-containing protein 27 [EC:2.3.2.27]"
				},
				{
					"name":"100717540 Trim28; transcription intermediary factor 1-beta\tK08882 TRIM28; tripartite motif-containing protein 28 [EC:2.3.2.27]"
				},
				{
					"name":"100716654 Trim29; tripartite motif-containing protein 29 isoform X2\tK12010 TRIM29; tripartite motif-containing protein 29"
				},
				{
					"name":"100725075 Trim32; E3 ubiquitin-protein ligase TRIM32\tK10607 TRIM32; tripartite motif-containing protein 32 [EC:2.3.2.27]"
				},
				{
					"name":"100719836 Trim33; E3 ubiquitin-protein ligase TRIM33 isoform X2\tK08883 TRIM33; tripartite motif-containing protein 33 [EC:2.3.2.27]"
				},
				{
					"name":"100734686 Trim35; tripartite motif-containing protein 35 isoform X2\tK12012 TRIM35; tripartite motif-containing protein 35"
				},
				{
					"name":"100735012 Trim36; E3 ubiquitin-protein ligase TRIM36\tK12013 TRIM36; tripartite motif-containing protein 36 [EC:2.3.2.27]"
				},
				{
					"name":"100714025 Trim37; LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase TRIM37\tK10608 TRIM37; tripartite motif-containing protein 37 [EC:2.3.2.27]"
				},
				{
					"name":"100713464 E3 ubiquitin-protein ligase TRIM38-like isoform X2\tK12014 TRIM38; tripartite motif-containing protein 38 [EC:2.3.2.27]"
				},
				{
					"name":"100714297 E3 ubiquitin-protein ligase TRIM38-like isoform X1\tK12014 TRIM38; tripartite motif-containing protein 38 [EC:2.3.2.27]"
				},
				{
					"name":"100715128 E3 ubiquitin-protein ligase TRIM38-like\tK12014 TRIM38; tripartite motif-containing protein 38 [EC:2.3.2.27]"
				},
				{
					"name":"100727489 E3 ubiquitin-protein ligase TRIM38 isoform X3\tK12014 TRIM38; tripartite motif-containing protein 38 [EC:2.3.2.27]"
				},
				{
					"name":"100734293 E3 ubiquitin-protein ligase TRIM39 isoform X1\tK12015 TRIM39; tripartite motif-containing protein 39 \/ bloodthirsty-related gene family protein [EC:2.3.2.27]"
				},
				{
					"name":"100733610 Trim41; LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase TRIM41\tK12017 TRIM41; tripartite motif-containing protein 41 [EC:2.3.2.27]"
				},
				{
					"name":"100733910 Trim42; tripartite motif-containing protein 42\tK12018 TRIM42; tripartite motif-containing protein 42"
				},
				{
					"name":"100730881 Trim44; tripartite motif-containing protein 44\tK12020 TRIM44; tripartite motif-containing protein 44"
				},
				{
					"name":"100733251 Trim46; tripartite motif-containing protein 46\tK12022 TRIM46; tripartite motif-containing protein 46"
				},
				{
					"name":"100720192 Trim47; LOW QUALITY PROTEIN: tripartite motif-containing protein 47\tK12023 TRIM47; tripartite motif-containing protein 47"
				},
				{
					"name":"100714398 Trim50; E3 ubiquitin-protein ligase TRIM50 isoform X1\tK12024 TRIM50_73_74; tripartite motif-containing protein 50\/73\/74"
				},
				{
					"name":"100727693 Trim54; tripartite motif-containing protein 54 isoform X1\tK10653 TRIM54; tripartite motif-containing protein 54"
				},
				{
					"name":"100719571 Trim55; tripartite motif-containing protein 55 isoform X1\tK10654 TRIM55; tripartite motif-containing protein 55"
				},
				{
					"name":"100727035 Trim56; LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase TRIM56\tK12026 TRIM56; tripartite motif-containing protein 56 [EC:2.3.2.27]"
				},
				{
					"name":"100730247 Trim58; E3 ubiquitin-protein ligase TRIM58\tK12027 TRIM58; tripartite motif-containing protein 58 [EC:2.3.2.27]"
				},
				{
					"name":"100732694 Trim59; tripartite motif-containing protein 59\tK12028 TRIM59; tripartite motif-containing protein 59"
				},
				{
					"name":"100722218 tripartite motif-containing protein 60-like\tK12029 TRIM60_61; tripartite motif-containing protein 60\/61"
				},
				{
					"name":"100723886 tripartite motif-containing protein 60-like\tK12029 TRIM60_61; tripartite motif-containing protein 60\/61"
				},
				{
					"name":"100726017 Trim62; E3 ubiquitin-protein ligase TRIM62\tK12030 TRIM62; tripartite motif-containing protein 62 [EC:2.3.2.27]"
				},
				{
					"name":"100716828 Trim63; E3 ubiquitin-protein ligase TRIM63\tK10655 TRIM63; tripartite motif-containing protein 63 [EC:2.3.2.27]"
				},
				{
					"name":"100720472 Trim65; tripartite motif-containing protein 65 isoform X2\tK12031 TRIM65; tripartite motif-containing protein 65"
				},
				{
					"name":"100731794 Trim66; tripartite motif-containing protein 66 isoform X1\tK12032 TRIM66; tripartite motif-containing protein 66"
				},
				{
					"name":"100720935 LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase TRIM68\tK12033 TRIM68; tripartite motif-containing protein 68 [EC:2.3.2.27]"
				},
				{
					"name":"100732949 Trim69; E3 ubiquitin-protein ligase TRIM69\tK12034 TRIM69; tripartite motif-containing protein 69 [EC:2.3.2.27]"
				},
				{
					"name":"100721907 Trim71; E3 ubiquitin-protein ligase TRIM71\tK12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]"
				},
				{
					"name":"100718437 Trim72; tripartite motif-containing protein 72\tK12036 TRIM72; tripartite motif-containing protein 72"
				}
				]
			},
			{
				"name":"UBR box proteins",
				"children":[
				{
					"name":"100715624 Ubr1; LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase UBR1\tK10625 UBR1; E3 ubiquitin-protein ligase UBR1 [EC:2.3.2.27]"
				},
				{
					"name":"100713673 Ubr2; E3 ubiquitin-protein ligase UBR2 isoform X1\tK10626 UBR2; E3 ubiquitin-protein ligase UBR2 [EC:2.3.2.27]"
				},
				{
					"name":"100735875 Ubr3; LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase UBR3\tK11978 UBR3; E3 ubiquitin-protein ligase UBR3 [EC:2.3.2.27]"
				},
				{
					"name":"100725123 Ubr4; E3 ubiquitin-protein ligase UBR4 isoform X7\tK10691 UBR4; E3 ubiquitin-protein ligase UBR4 [EC:2.3.2.27]"
				},
				{
					"name":"100717054 Ubr7; putative E3 ubiquitin-protein ligase UBR7\tK11979 UBR7; E3 ubiquitin-protein ligase UBR7 [EC:2.3.2.27]"
				}
				]
			},
			{
				"name":"ATL proteins"
			},
			{
				"name":"Other single Ring-finger type E3",
				"children":[
				{
					"name":"100729655 Amfr; E3 ubiquitin-protein ligase AMFR\tK10636 AMFR; E3 ubiquitin-protein ligase AMFR [EC:2.3.2.36]"
				},
				{
					"name":"100729880 Aire; autoimmune regulator isoform X1\tK10603 AIRE; autoimmune regulator"
				},
				{
					"name":"100732611 Bfar; bifunctional apoptosis regulator\tK15684 BFAR; bifunctional apoptosis regulator"
				},
				{
					"name":"100713574 Birc3; baculoviral IAP repeat-containing protein 3\tK16060 BIRC2_3; baculoviral IAP repeat-containing protein 2\/3"
				},
				{
					"name":"100715527 Birc2; baculoviral IAP repeat-containing protein 2\tK16060 BIRC2_3; baculoviral IAP repeat-containing protein 2\/3"
				},
				{
					"name":"100715778 Xiap; E3 ubiquitin-protein ligase XIAP\tK04725 XIAP; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]"
				},
				{
					"name":"100717708 Birc7; baculoviral IAP repeat-containing protein 7\tK16061 BIRC7_8; baculoviral IAP repeat-containing protein 7\/8"
				},
				{
					"name":"100729597 Brap; BRCA1-associated protein\tK10632 BRAP; BRCA1-associated protein [EC:2.3.2.27]"
				},
				{
					"name":"100722339 Brca1; breast cancer type 1 susceptibility protein isoform X2\tK10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]"
				},
				{
					"name":"100718115 Cbll1; E3 ubiquitin-protein ligase Hakai\tK15685 CBLL1; E3 ubiquitin-protein ligase Hakai [EC:2.3.2.27]"
				},
				{
					"name":"100719895 Ccnb1ip1; E3 ubiquitin-protein ligase CCNB1IP1\tK10639 CCNB1IP1; E3 ubiquitin-protein ligase CCNP1IP1 [EC:2.3.2.27]"
				},
				{
					"name":"100725607 Chfr; E3 ubiquitin-protein ligase CHFR isoform X5\tK10644 CHFR; E3 ubiquitin-protein ligase CHFR [EC:2.3.2.27]"
				},
				{
					"name":"100721176 Cnot4; LOW QUALITY PROTEIN: CCR4-NOT transcription complex subunit 4\tK10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]"
				},
				{
					"name":"100732133 Dcst1; E3 ubiquitin-protein ligase DCST1\tK22375 DCST1; E3 ubiquitin-protein ligase DCST1 [EC:2.3.2.27]"
				},
				{
					"name":"100717246 Dtx3l; E3 ubiquitin-protein ligase DTX3L\tK06058 DTX; deltex [EC:2.3.2.27]"
				},
				{
					"name":"100722682 Dtx1; LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase DTX1\tK06058 DTX; deltex [EC:2.3.2.27]"
				},
				{
					"name":"100723700 Dtx4; E3 ubiquitin-protein ligase DTX4\tK06058 DTX; deltex [EC:2.3.2.27]"
				},
				{
					"name":"100726658 Dtx2; probable E3 ubiquitin-protein ligase DTX2 isoform X1\tK06058 DTX; deltex [EC:2.3.2.27]"
				},
				{
					"name":"100729451 Dzip3; E3 ubiquitin-protein ligase DZIP3\tK10642 DZIP3; E3 ubiquitin-protein ligase DZIP3 [EC:2.3.2.27]"
				},
				{
					"name":"100720230 Fancl; E3 ubiquitin-protein ligase FANCL isoform X1\tK10606 FANCL; E3 ubiquitin-protein ligase FANCL [EC:2.3.2.27]"
				},
				{
					"name":"100731653 Kcmf1; LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase KCMF1\tK22376 KCMF1; E3 ubiquitin-protein ligase KCMF1 [EC:2.3.2.27]"
				},
				{
					"name":"100727397 Lrsam1; E3 ubiquitin-protein ligase LRSAM1 isoform X1\tK10641 LRSAM1; E3 ubiquitin-protein ligase LRSAM1 [EC:2.3.2.27]"
				},
				{
					"name":"100714290 Ltn1; E3 ubiquitin-protein ligase listerin\tK22377 LTN1; E3 ubiquitin-protein ligase listerin [EC:2.3.2.27]"
				},
				{
					"name":"100723456 Map3k1; LOW QUALITY PROTEIN: mitogen-activated protein kinase kinase kinase 1\tK04416 MAP3K1; mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25]"
				},
				{
					"name":"100712953 Mex3d; LOW QUALITY PROTEIN: RNA-binding protein MEX3D\tK15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]"
				},
				{
					"name":"100713484 Mex3c; LOW QUALITY PROTEIN: RNA-binding E3 ubiquitin-protein ligase MEX3C\tK15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]"
				},
				{
					"name":"100720730 Mex3a; LOW QUALITY PROTEIN: RNA-binding protein MEX3A\tK15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]"
				},
				{
					"name":"100728833 Mex3b; LOW QUALITY PROTEIN: RNA-binding protein MEX3B\tK15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]"
				},
				{
					"name":"100720916 Mgrn1; E3 ubiquitin-protein ligase MGRN1 isoform X2\tK10604 MGRN1; E3 ubiquitin-protein ligase MGRN1 [EC:2.3.2.27]"
				},
				{
					"name":"100721079 Mib1; E3 ubiquitin-protein ligase MIB1\tK10645 MIB; E3 ubiquitin-protein ligase mind-bomb [EC:2.3.2.27]"
				},
				{
					"name":"100727066 Mib2; LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase MIB2\tK10645 MIB; E3 ubiquitin-protein ligase mind-bomb [EC:2.3.2.27]"
				},
				{
					"name":"100714537 Mkrn2; probable E3 ubiquitin-protein ligase makorin-2 isoform X1\tK15687 MKRN; E3 ubiquitin-protein ligase makorin [EC:2.3.2.27]"
				},
				{
					"name":"100720902 Mkrn3; probable E3 ubiquitin-protein ligase makorin-3\tK15687 MKRN; E3 ubiquitin-protein ligase makorin [EC:2.3.2.27]"
				},
				{
					"name":"100722285 Mkrn1; E3 ubiquitin-protein ligase makorin-1 isoform X2\tK15687 MKRN; E3 ubiquitin-protein ligase makorin [EC:2.3.2.27]"
				},
				{
					"name":"100721068 Mul1; mitochondrial ubiquitin ligase activator of NFKB 1\tK15688 MUL1; E3 ubiquitin-protein ligase MUL1 [EC:2.3.2.27]"
				},
				{
					"name":"100726232 Mycbp2; LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase MYCBP2\tK10693 MYCBP2; RCR-type E3 ubiquitin transferase [EC:2.3.2.33]"
				},
				{
					"name":"100719127 Mylip; LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase MYLIP\tK10637 MYLIP; E3 ubiquitin-protein ligase MYLIP [EC:2.3.2.27]"
				},
				{
					"name":"100717668 Neurl1b; E3 ubiquitin-protein ligase NEURL1B\tK01931 NEUR; protein neuralized [EC:2.3.2.27]"
				},
				{
					"name":"100721634 Neurl1; E3 ubiquitin-protein ligase NEURL1 isoform X1\tK01931 NEUR; protein neuralized [EC:2.3.2.27]"
				},
				{
					"name":"100715145 Neurl3; E3 ubiquitin-protein ligase NEURL3\tK15689 NEURL3; E3 ubiquitin-protein ligase NEURL3 [EC:2.3.2.27]"
				},
				{
					"name":"100731006 Nhlrc1; E3 ubiquitin-protein ligase NHLRC1\tK10602 NHLRC1; E3 ubiquitin-protein ligase NHLRC1 [EC:2.3.2.27]"
				},
				{
					"name":"100729851 Rnf219; RING finger protein 219 isoform X1\tK24091 OBI1; ORC ubiquitin ligase 1 [EC:2.3.2.27]"
				},
				{
					"name":"100714812 Pja2; E3 ubiquitin-protein ligase Praja-2\tK10634 PJA2; E3 ubiquitin-protein ligase Praja2 [EC:2.3.2.27]"
				},
				{
					"name":"100720939 Rad18; E3 ubiquitin-protein ligase RAD18\tK10627 RAD18; E3 ubiquitin-protein ligase RAD18 [EC:2.3.2.27]"
				},
				{
					"name":"100724169 Rag1; V(D)J recombination-activating protein 1\tK10628 RAG1; V(D)J recombination-activating protein 1 [EC:2.3.2.27]"
				},
				{
					"name":"100713655 Rc3h2; roquin-2 isoform X1\tK15690 RC3H; RING finger and CCCH-type zinc finger domain-containing protein"
				},
				{
					"name":"100730486 Rc3h1; LOW QUALITY PROTEIN: roquin-1\tK15690 RC3H; RING finger and CCCH-type zinc finger domain-containing protein"
				},
				{
					"name":"100728351 Cop1; E3 ubiquitin-protein ligase RFWD2\tK10143 RFWD2; E3 ubiquitin-protein ligase RFWD2 [EC:2.3.2.27]"
				},
				{
					"name":"100716272 Rfwd3; E3 ubiquitin-protein ligase RFWD3 isoform X1\tK15691 RFWD3; E3 ubiquitin-protein ligase RFWD3 [EC:2.3.2.27]"
				},
				{
					"name":"100717673 Rnf2; E3 ubiquitin-protein ligase RING2\tK10695 RNF1_2; E3 ubiquitin-protein ligase RNF1\/2 [EC:2.3.2.27]"
				},
				{
					"name":"100732401 Ring1; E3 ubiquitin-protein ligase RING1 isoform X2\tK10695 RNF1_2; E3 ubiquitin-protein ligase RNF1\/2 [EC:2.3.2.27]"
				},
				{
					"name":"100735750 Rnf4; E3 ubiquitin-protein ligase RNF4 isoform X1\tK22651 RNF4; E3 ubiquitin-protein ligase RNF4 [EC:2.3.2.27]"
				},
				{
					"name":"100713396 Rnf5; E3 ubiquitin-protein ligase RNF5\tK10666 RNF5_185; E3 ubiquitin-protein ligase RNF5\/185 [EC:2.3.2.27]"
				},
				{
					"name":"100731418 Rnf185; E3 ubiquitin-protein ligase RNF185 isoform X1\tK10666 RNF5_185; E3 ubiquitin-protein ligase RNF5\/185 [EC:2.3.2.27]"
				},
				{
					"name":"100730117 Rnf6; LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase RNF6\tK22753 RNF6; E3 ubiquitin-protein ligase RNF6 [EC:2.3.2.27]"
				},
				{
					"name":"100725403 Rnf8; E3 ubiquitin-protein ligase RNF8 isoform X1\tK10667 RNF8; E3 ubiquitin-protein ligase RNF8 [EC:2.3.2.27]"
				},
				{
					"name":"100727163 Rnf10; LOW QUALITY PROTEIN: RING finger protein 10\tK26979 RNF10; E3 ubiquitin-protein ligase RNF10 [EC:2.3.2.27]"
				},
				{
					"name":"100720933 Rnf11; RING finger protein 11\tK11980 RNF11; E3 ubiquitin-protein ligase RNF11"
				},
				{
					"name":"100719423 Rlim; E3 ubiquitin-protein ligase RLIM\tK16271 RLIM; E3 ubiquitin-protein ligase RLIM [EC:2.3.2.27]"
				},
				{
					"name":"100720090 Rnf13; E3 ubiquitin-protein ligase RNF13\tK15692 RNF13; E3 ubiquitin-protein ligase RNF13 [EC:2.3.2.27]"
				},
				{
					"name":"100713895 Rnf25; E3 ubiquitin-protein ligase RNF25\tK10640 RNF25; E3 ubiquitin-protein ligase RNF25 [EC:2.3.2.27]"
				},
				{
					"name":"100717945 Rnf26; E3 ubiquitin-protein ligase RNF26\tK15693 RNF26; E3 ubiquitin-protein ligase RNF26 [EC:2.3.2.27]"
				},
				{
					"name":"100731657 Rnf38; E3 ubiquitin-protein ligase RNF38\tK19041 RNF38_44; E3 ubiquitin-protein ligase RNF38\/44 [EC:2.3.2.27]"
				},
				{
					"name":"100731945 Rnf44; RING finger protein 44 isoform X1\tK19041 RNF38_44; E3 ubiquitin-protein ligase RNF38\/44 [EC:2.3.2.27]"
				},
				{
					"name":"100734563 Rnf41; E3 ubiquitin-protein ligase NRDP1 isoform X1\tK11981 RNF41; E3 ubiquitin-protein ligase NRDP1 [EC:2.3.2.27]"
				},
				{
					"name":"100725020 Rnf43; E3 ubiquitin-protein ligase RNF43\tK15694 RNF43; E3 ubiquitin-protein ligase RNF43 [EC:2.3.2.27]"
				},
				{
					"name":"106027497 Rnf103; LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase RNF103\tK15695 RNF103; E3 ubiquitin-protein ligase RNF103 [EC:2.3.2.27]"
				},
				{
					"name":"100715851 Rnf111; E3 ubiquitin-protein ligase Arkadia isoform X5\tK10635 RNF111; E3 ubiquitin-protein ligase Arkadia [EC:2.3.2.27]"
				},
				{
					"name":"100728675 Rnf112; LOW QUALITY PROTEIN: RING finger protein 112\tK25173 RNF112; E3 ubiquitin-protein ligase RNF112 [EC:2.3.2.27]"
				},
				{
					"name":"100726743 Rnf114; E3 ubiquitin-protein ligase RNF114\tK15697 RNF114; E3 ubiquitin-protein ligase RNF114 [EC:2.3.2.27]"
				},
				{
					"name":"100719558 Rnf115; E3 ubiquitin-protein ligase RNF115\tK11982 RNF115_126; E3 ubiquitin-protein ligase RNF115\/126 [EC:2.3.2.27]"
				},
				{
					"name":"100720741 Rnf126; E3 ubiquitin-protein ligase RNF126\tK11982 RNF115_126; E3 ubiquitin-protein ligase RNF115\/126 [EC:2.3.2.27]"
				},
				{
					"name":"100727359 Rnf121; RING finger protein 121\tK15698 RNF121_175; RING finger protein 121\/175"
				},
				{
					"name":"100722006 Rnf122; RING finger protein 122 isoform X1\tK15699 RNF122; RING finger protein 122"
				},
				{
					"name":"100730766 Rnf123; E3 ubiquitin-protein ligase RNF123 isoform X2\tK12169 KPC1; Kip1 ubiquitination-promoting complex protein 1 [EC:2.3.2.27]"
				},
				{
					"name":"100715433 Rnf125; E3 ubiquitin-protein ligase RNF125 isoform X2\tK12170 RNF125; E3 ubiquitin-protein ligase RNF125 [EC:2.3.2.27]"
				},
				{
					"name":"100726928 Rnf128; E3 ubiquitin-protein ligase RNF128\tK10629 RNF128; E3 ubiquitin-protein ligase RNF128 [EC:2.3.2.27]"
				},
				{
					"name":"100722652 Rnf133; E3 ubiquitin-protein ligase RNF133\tK15702 RNF133; E3 ubiquitin-protein ligase RNF133 [EC:2.3.2.27]"
				},
				{
					"name":"100718859 Rnf135; LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase RNF135\tK16272 RNF135; E3 ubiquitin-protein ligase RNF135 [EC:2.3.2.27]"
				},
				{
					"name":"100715155 Rnf138; E3 ubiquitin-protein ligase RNF138 isoform X2\tK10668 RNF138; E3 ubiquitin-protein ligase RNF138 [EC:2.3.2.27]"
				},
				{
					"name":"100734055 Rnf139; E3 ubiquitin-protein ligase RNF139\tK15703 RNF139; E3 ubiquitin-protein ligase RNF139 [EC:2.3.2.27]"
				},
				{
					"name":"100733242 Rnf145; LOW QUALITY PROTEIN: RING finger protein 145\tK23789 RNF145; E3 ubiquitin-protein ligase RNF145 [EC:2.3.2.27]"
				},
				{
					"name":"100719837 Rnf146; E3 ubiquitin-protein ligase RNF146\tK15700 RNF146; E3 ubiquitin-protein ligase RNF146 [EC:2.3.2.27]"
				},
				{
					"name":"100722823 Rnf149; E3 ubiquitin-protein ligase RNF149\tK15704 RNF149; E3 ubiquitin-protein ligase RNF149 [EC:2.3.2.27]"
				},
				{
					"name":"100718418 Rnf152; E3 ubiquitin-protein ligase RNF152\tK15705 RNF152; E3 ubiquitin-protein ligase RNF152 [EC:2.3.2.27]"
				},
				{
					"name":"100723130 Rnf157; E3 ubiquitin ligase RNF157 isoform X1\tK25192 RNF157; E3 ubiquitin-protein ligase RNF157 [EC:2.3.2.27]"
				},
				{
					"name":"100718877 Rnf165; E3 ubiquitin-protein ligase RNF165\tK17821 RNF165; E3 ubiquitin-protein ligase RNF165 [EC:2.3.2.27]"
				},
				{
					"name":"100731777 Rnf166; RING finger protein 166 isoform X1\tK17044 RNF166; E3 ubiquitin-protein ligase RNF166 [EC:2.3.2.27]"
				},
				{
					"name":"100717812 Rnf167; E3 ubiquitin-protein ligase RNF167 isoform X2\tK15706 RNF167; E3 ubiquitin-protein ligase RNF167 [EC:2.3.2.27]"
				},
				{
					"name":"100719157 Rnf170; E3 ubiquitin-protein ligase RNF170 isoform X1\tK15707 RNF170; E3 ubiquitin-protein ligase RNF170 [EC:2.3.2.27]"
				},
				{
					"name":"100720838 Rnf180; E3 ubiquitin-protein ligase RNF180\tK15708 RNF180; E3 ubiquitin-protein ligase RNF180 [EC:2.3.2.27]"
				},
				{
					"name":"100729723 Rnf181; E3 ubiquitin-protein ligase RNF181 isoform X2\tK22378 RNF181; E3 ubiquitin-protein ligase RNF181 [EC:2.3.2.27]"
				},
				{
					"name":"100718581 Rnf182; E3 ubiquitin-protein ligase RNF182\tK11983 RNF182; E3 ubiquitin-protein ligase RNF182 [EC:2.3.2.27]"
				},
				{
					"name":"100722729 Rnf186; RING finger protein 186\tK25214 RNF186; E3 ubiquitin-protein ligase RNF186 [EC:2.3.2.27]"
				},
				{
					"name":"100729204 Rnf187; E3 ubiquitin-protein ligase RNF187\tK15709 RNF187; E3 ubiquitin-protein ligase RNF187 [EC:2.3.2.27]"
				},
				{
					"name":"100733579 Rnf213; E3 ubiquitin-protein ligase RNF213\tK22754 RNF213; E3 ubiquitin-protein ligase RNF213 [EC:2.3.2.27]"
				},
				{
					"name":"100721371 Rnf220; E3 ubiquitin-protein ligase RNF220 isoform X2\tK25174 RNF220; E3 ubiquitin-protein ligase RNF220 [EC:2.3.2.27]"
				},
				{
					"name":"100728980 Rnft1; E3 ubiquitin-protein ligase RNFT1\tK22379 RNFT1; E3 ubiquitin-protein ligase RNFT1 [EC:2.3.2.27]"
				},
				{
					"name":"100727896 Rnft2; RING finger and transmembrane domain-containing protein 2\tK28516 RNFT2; E3 ubiquitin-protein ligase RNFT2"
				},
				{
					"name":"100725917 Sart1; LOW QUALITY PROTEIN: U4\/U6.U5 tri-snRNP-associated protein 1\tK11984 SART1; U4\/U6.U5 tri-snRNP-associated protein 1"
				},
				{
					"name":"100730609 Shprh; E3 ubiquitin-protein ligase SHPRH\tK15710 SHPRH; E3 ubiquitin-protein ligase SHPRH [EC:5.6.2.- 2.3.2.27]"
				},
				{
					"name":"100713199 Sh3rf3; SH3 domain-containing RING finger protein 3 isoform X1\tK12171 SH3RF; E3 ubiquitin-protein ligase SH3RF [EC:2.3.2.27]"
				},
				{
					"name":"100728797 Sh3rf1; E3 ubiquitin-protein ligase SH3RF1\tK12171 SH3RF; E3 ubiquitin-protein ligase SH3RF [EC:2.3.2.27]"
				},
				{
					"name":"100729949 Sh3rf2; putative E3 ubiquitin-protein ligase SH3RF2\tK12171 SH3RF; E3 ubiquitin-protein ligase SH3RF [EC:2.3.2.27]"
				},
				{
					"name":"100716292 Hltf; helicase-like transcription factor isoform X2\tK15711 SMARCA3; SWI\/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A3 [EC:5.6.2. 2.3.2.27]"
				},
				{
					"name":"100722976 Syvn1; LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase synoviolin\tK10601 SYVN1; E3 ubiquitin-protein ligase synoviolin [EC:2.3.2.27]"
				},
				{
					"name":"100719977 Tmem129; E3 ubiquitin-protein ligase TM129\tK22380 TMEM129; E3 ubiquitin-protein ligase TM129 [EC:2.3.2.27]"
				},
				{
					"name":"100718772 Topors; E3 ubiquitin-protein ligase Topors isoform X1\tK10631 TOPORS; E3 ubiquitin-protein ligase Topors [EC:2.3.2.27]"
				},
				{
					"name":"100713133 Traip; E3 ubiquitin-protein ligase TRAIP isoform X2\tK11985 TRAIP; TRAF-interacting protein [EC:2.3.2.27]"
				},
				{
					"name":"100715382 Ttc3; E3 ubiquitin-protein ligase TTC3 isoform X1\tK15712 TTC3; E3 ubiquitin-protein ligase TTC3 [EC:2.3.2.27]"
				},
				{
					"name":"100719542 Uhrf1; E3 ubiquitin-protein ligase UHRF1 isoform X1\tK10638 UHRF1; E3 ubiquitin-protein ligase UHRF1 [EC:2.3.2.27]"
				},
				{
					"name":"100715709 Uhrf2; E3 ubiquitin-protein ligase UHRF2 isoform X1\tK15713 UHRF2; E3 ubiquitin-protein ligase UHRF2 [EC:2.3.2.27]"
				},
				{
					"name":"100723408 Unkl; putative E3 ubiquitin-protein ligase UNKL isoform X1\tK23047 UNKL; E3 ubiquitin-protein ligase UNKL [EC:2.3.2.27]"
				},
				{
					"name":"100730683 Znf598; E3 ubiquitin-protein ligase ZNF598 isoform X1\tK22381 ZNF598; E3 ubiquitin-protein ligase ZNF598 [EC:2.3.2.27]"
				},
				{
					"name":"100725175 Zfp91; E3 ubiquitin-protein ligase ZFP91\tK25175 ZFP91; E3 ubiquitin-protein ligase ZFP91 [EC:2.3.2.27]"
				},
				{
					"name":"100730744 Znrf1; E3 ubiquitin-protein ligase ZNRF1\tK10694 ZNRF1_2; E3 ubiquitin-protein ligase ZNRF1\/2 [EC:2.3.2.27]"
				},
				{
					"name":"100727159 Znrf3; E3 ubiquitin-protein ligase ZNRF3\tK16273 ZNRF3; E3 ubiquitin-protein ligase ZNRF3 [EC:2.3.2.27]"
				},
				{
					"name":"100736068 Zswim2; E3 ubiquitin-protein ligase ZSWIM2 isoform X2\tK15716 ZSWIM2; E3 ubiquitin-protein ligase ZSWIM2 [EC:2.3.2.27]"
				}
				]
			}
			]
		},
		{
			"name":"Atypical E3",
			"children":[
			{
				"name":"100724450 Jade2; E3 ubiquitin-protein ligase Jade-2 isoform X1\tK22155 JADE2; E3 ubiquitin-protein ligase Jade-2 [EC:2.3.2.27]"
			},
			{
				"name":"100733176 E4f1; transcription factor E4F1 isoform X4\tK22401 E4F1; transcription factor E4F1 \/ E3 ubiquitin-protein ligase [EC:2.3.2.27]"
			},
			{
				"name":"100721287 Nsmce1; non-structural maintenance of chromosomes element 1 homolog isoform X2\tK22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27]"
			},
			{
				"name":"100716834 Irf2bpl; LOW QUALITY PROTEIN: interferon regulatory factor 2-binding protein-like\tK22383 IRF2BP; interferon regulatory factor 2-binding protein"
			},
			{
				"name":"100723795 Irf2bp1; interferon regulatory factor 2-binding protein 1\tK22383 IRF2BP; interferon regulatory factor 2-binding protein"
			}
			]
		},
		{
			"name":"UBL E3 ligases",
			"children":[
			{
				"name":"100714763 Rbx1; E3 ubiquitin-protein ligase RBX1\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
			},
			{
				"name":"100718772 Topors; E3 ubiquitin-protein ligase Topors isoform X1\tK10631 TOPORS; E3 ubiquitin-protein ligase Topors [EC:2.3.2.27]"
			},
			{
				"name":"101788077 LOW QUALITY PROTEIN: E3 SUMO-protein ligase RanBP2\tK12172 RANBP2; E3 SUMO-protein ligase RanBP2 [EC:2.3.2.-]"
			},
			{
				"name":"100729878 Pias1; E3 SUMO-protein ligase PIAS1 isoform X1\tK04706 PIAS1; E3 SUMO-protein ligase PIAS1 [EC:2.3.2.-]"
			},
			{
				"name":"100718605 Pias2; E3 SUMO-protein ligase PIAS2\tK16063 PIAS2; E3 SUMO-protein ligase PIAS2 [EC:2.3.2.-]"
			},
			{
				"name":"100725700 LOW QUALITY PROTEIN: E3 SUMO-protein ligase PIAS2-like\tK16063 PIAS2; E3 SUMO-protein ligase PIAS2 [EC:2.3.2.-]"
			},
			{
				"name":"100731803 LOW QUALITY PROTEIN: E3 SUMO-protein ligase PIAS2-like\tK16063 PIAS2; E3 SUMO-protein ligase PIAS2 [EC:2.3.2.-]"
			},
			{
				"name":"100730313 Pias3; E3 SUMO-protein ligase PIAS3 isoform X1\tK16064 PIAS3; E3 SUMO-protein ligase PIAS3 [EC:2.3.2.-]"
			},
			{
				"name":"100729680 Pias4; E3 SUMO-protein ligase PIAS4\tK16065 PIAS4; E3 SUMO-protein ligase PIAS4 [EC:2.3.2.27]"
			},
			{
				"name":"100720832 Pml; protein PML isoform X1\tK10054 PML; E3 SUMO-protein ligase PML [EC:2.3.2.-]"
			},
			{
				"name":"100732734 Cbx4; E3 SUMO-protein ligase CBX4\tK11452 CBX4; E3 SUMO-protein ligase CBX4 [EC:2.3.2.-]"
			},
			{
				"name":"100724833 Nsmce2; E3 SUMO-protein ligase NSE2\tK22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]"
			},
			{
				"name":"101788640 Rnf212; probable E3 SUMO-protein ligase RNF212\tK25662 RNF212; E3 SUMO-protein ligase RNF212 [EC:2.3.2.-]"
			},
			{
				"name":"106028690 Rnf212b; RING finger protein 212B\tK25662 RNF212; E3 SUMO-protein ligase RNF212 [EC:2.3.2.-]"
			},
			{
				"name":"100727278 Znf451; E3 SUMO-protein ligase ZNF451 isoform X2\tK25176 ZNF451; E3 SUMO-protein ligase ZNF451 [EC:2.3.2.-]"
			},
			{
				"name":"100717178 Herc6; probable E3 ubiquitin-protein ligase HERC6\tK22372 HERC5_6; E3 ISG15--protein ligase [EC:2.3.2.-]"
			},
			{
				"name":"100717453 Herc5; E3 ISG15--protein ligase HERC5\tK22372 HERC5_6; E3 ISG15--protein ligase [EC:2.3.2.-]"
			},
			{
				"name":"100734148 Ufl1; LOW QUALITY PROTEIN: E3 UFM1-protein ligase 1\tK22755 UFL1; E3 UFM1-protein ligase 1 [EC:2.3.2.-]"
			},
			{
				"name":"100725414 Dcun1d1; DCN1-like protein 1\tK17822 DCUN1D1_2; DCN1-like protein 1\/2"
			},
			{
				"name":"100726054 Dcun1d2; DCN1-like protein 2 isoform X1\tK17822 DCUN1D1_2; DCN1-like protein 1\/2"
			},
			{
				"name":"100716861 Dcun1d3; DCN1-like protein 3\tK17823 DCUN1D3; DCN1-like protein 3"
			},
			{
				"name":"100722822 Dcun1d4; DCN1-like protein 4 isoform X2\tK17824 DCUN1D4_5; DCN1-like protein 4\/5"
			},
			{
				"name":"100728820 Dcun1d5; DCN1-like protein 5\tK17824 DCUN1D4_5; DCN1-like protein 4\/5"
			}
			]
		},
		{
			"name":"Multi subunit type E3",
			"children":[
			{
				"name":"SCF complex",
				"children":[
				{
					"name":"Ring finger protein",
					"children":[
					{
						"name":"100714763 Rbx1; E3 ubiquitin-protein ligase RBX1\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
					}
					]
				},
				{
					"name":"Cullin",
					"children":[
					{
						"name":"100727053 Cul1; cullin-1\tK03347 CUL1; cullin 1"
					}
					]
				},
				{
					"name":"Adaptor protein",
					"children":[
					{
						"name":"100135616 Skp1; S-phase kinase-associated protein 1\tK03094 SKP1; S-phase kinase-associated protein 1"
					}
					]
				},
				{
					"name":"Target recognizing subunit (F-box)",
					"children":[
					{
						"name":"100715997 Fbxw11; F-box\/WD repeat-containing protein 11\tK03362 FBXW1_11; F-box and WD-40 domain protein 1\/11"
					},
					{
						"name":"100730107 Btrc; LOW QUALITY PROTEIN: F-box\/WD repeat-containing protein 1A\tK03362 FBXW1_11; F-box and WD-40 domain protein 1\/11"
					},
					{
						"name":"100723973 Fbxw2; F-box\/WD repeat-containing protein 2 isoform X1\tK10261 FBXW2; F-box and WD-40 domain protein 2"
					},
					{
						"name":"100721914 Fbxw4; F-box\/WD repeat-containing protein 4\tK10262 FBXW4; F-box and WD-40 domain protein 4"
					},
					{
						"name":"100732858 Fbxw5; F-box\/WD repeat-containing protein 5 isoform X1\tK10263 FBXW5; F-box and WD-40 domain protein 5"
					},
					{
						"name":"100734383 Fbxw7; F-box\/WD repeat-containing protein 7 isoform X1\tK10260 FBXW7; F-box and WD-40 domain protein 7"
					},
					{
						"name":"100728842 Fbxw8; F-box\/WD repeat-containing protein 8\tK10264 FBXW8; F-box and WD-40 domain protein 8"
					},
					{
						"name":"100717363 Fbxw9; F-box\/WD repeat-containing protein 9 isoform X3\tK10265 FBXW9; F-box and WD-40 domain protein 9"
					},
					{
						"name":"100731178 Cdrt1; CMT1A duplicated region transcript 1 protein\tK10266 FBXW10; F-box and WD-40 domain protein 10"
					},
					{
						"name":"100724187 Fbxw12; F-box\/WD repeat-containing protein 12 isoform X2\tK10267 FBXW12S; F-box and WD-40 domain protein 12\/13\/14\/15\/16\/17\/19"
					},
					{
						"name":"100720705 Skp2; S-phase kinase-associated protein 2 isoform X1\tK03875 SKP2; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)"
					},
					{
						"name":"100719708 Fbxl2; F-box\/LRR-repeat protein 2 isoform X4\tK10268 FBXL2_20; F-box and leucine-rich repeat protein 2\/20"
					},
					{
						"name":"100722528 Fbxl20; F-box\/LRR-repeat protein 20 isoform X1\tK10268 FBXL2_20; F-box and leucine-rich repeat protein 2\/20"
					},
					{
						"name":"100730124 Fbxl3; F-box\/LRR-repeat protein 3\tK10269 FBXL3; F-box and leucine-rich repeat protein 3"
					},
					{
						"name":"100723716 Fbxl4; LOW QUALITY PROTEIN: F-box\/LRR-repeat protein 4\tK10270 FBXL4; F-box and leucine-rich repeat protein 4"
					},
					{
						"name":"100730429 Fbxl5; F-box\/LRR-repeat protein 5 isoform X2\tK10271 FBXL5; F-box and leucine-rich repeat protein 5"
					},
					{
						"name":"100735196 F-box\/LRR-repeat protein 5-like isoform X1\tK10271 FBXL5; F-box and leucine-rich repeat protein 5"
					},
					{
						"name":"100734128 Fbxl6; F-box\/LRR-repeat protein 6 isoform X1\tK10272 FBXL6; F-box and leucine-rich repeat protein 6"
					},
					{
						"name":"100720048 Fbxl7; F-box\/LRR-repeat protein 7 isoform X1\tK10273 FBXL7; F-box and leucine-rich repeat protein 7"
					},
					{
						"name":"100713293 Fbxl8; F-box\/LRR-repeat protein 8\tK10274 FBXL8; F-box and leucine-rich repeat protein 8"
					},
					{
						"name":"100734543 F-box\/LRR-repeat protein 2 isoform X1\tK10275 FBXL9; F-box and leucine-rich repeat protein 9"
					},
					{
						"name":"100726076 Kdm2b; lysine-specific demethylase 2B isoform X4\tK10276 FBXL10_11; F-box and leucine-rich repeat protein 10\/11 [EC:1.14.11.27]"
					},
					{
						"name":"100732285 Kdm2a; lysine-specific demethylase 2A isoform X1\tK10276 FBXL10_11; F-box and leucine-rich repeat protein 10\/11 [EC:1.14.11.27]"
					},
					{
						"name":"100726883 Fbxl12; F-box\/LRR-repeat protein 12\tK10278 FBXL12; F-box and leucine-rich repeat protein 12"
					},
					{
						"name":"100724753 Fbxl13; F-box\/LRR-repeat protein 13\tK10279 FBXL13; dynein regulatory complex subunit 6"
					},
					{
						"name":"100720585 Fbxl14; F-box\/LRR-repeat protein 14\tK10280 FBXL14; F-box and leucine-rich repeat protein 14"
					},
					{
						"name":"100713858 Fbxl15; F-box\/LRR-repeat protein 15\tK10281 FBXL15; F-box and leucine-rich repeat protein 15"
					},
					{
						"name":"100718163 Fbxl16; F-box\/LRR-repeat protein 16\tK10282 FBXL16; F-box and leucine-rich repeat protein 16"
					},
					{
						"name":"100723027 F-box\/LRR-repeat protein 17-like\tK10283 FBXL17; F-box and leucine-rich repeat protein 17"
					},
					{
						"name":"100728425 Fbxl18; F-box\/LRR-repeat protein 18 isoform X1\tK10284 FBXL18; F-box and leucine-rich repeat protein 18"
					},
					{
						"name":"100732335 Fbxl19; F-box\/LRR-repeat protein 19 isoform X2\tK10285 FBXL19; F-box and leucine-rich repeat protein 19"
					},
					{
						"name":"100716741 Fbxl21; F-box\/LRR-repeat protein 21\tK10287 FBXL21; F-box and leucine-rich repeat protein 21"
					},
					{
						"name":"100734304 Ccnf; cyclin-F\tK10289 CCNF; F-box protein 1 (cyclin F)"
					},
					{
						"name":"100322881 Fbxo2; F-box only protein 2\tK10099 FBXO2; F-box protein 2"
					},
					{
						"name":"100727000 Fbxo3; F-box only protein 3\tK10290 FBXO3; F-box protein 3"
					},
					{
						"name":"100735926 Fbxo4; F-box only protein 4\tK10291 FBXO4; F-box protein 4"
					},
					{
						"name":"100714021 Fbxo5; F-box only protein 5\tK10292 FBXO5; F-box protein 5"
					},
					{
						"name":"100724661 F-box only protein 6\tK10100 FBXO6; F-box protein 6"
					},
					{
						"name":"100735044 Fbxo7; F-box only protein 7 isoform X1\tK10293 FBXO7; F-box protein 7"
					},
					{
						"name":"100726283 Fbxo8; F-box only protein 8\tK10294 FBXO8; F-box protein 8"
					},
					{
						"name":"101788238 Fbxo9; F-box only protein 9\tK10295 FBXO9; F-box protein 9"
					},
					{
						"name":"100733039 Fbxo10; LOW QUALITY PROTEIN: F-box only protein 10\tK10296 FBXO10; F-box protein 10"
					},
					{
						"name":"100729179 Fbxo11; F-box only protein 11 isoform X1\tK10297 FBXO11; F-box protein 11"
					},
					{
						"name":"100730441 Fbxo15; F-box only protein 15\tK10298 FBXO15; F-box protein 15"
					},
					{
						"name":"100720112 Fbxo16; F-box only protein 16 isoform X2\tK10299 FBXO16; F-box protein 16"
					},
					{
						"name":"100735358 Fbxo17; F-box only protein 17\tK10101 FBXO17; F-box protein 17"
					},
					{
						"name":"100715614 Fbxo18; F-box DNA helicase 1\tK10300 FBH1; F-box DNA helicase 1 [EC:5.6.2.4]"
					},
					{
						"name":"100727615 Lmo7; LIM domain only protein 7 isoform X6\tK06084 LMO7; F-box protein 20"
					},
					{
						"name":"100718831 LOW QUALITY PROTEIN: F-box only protein 21-like\tK10301 FBXO21; F-box protein 21"
					},
					{
						"name":"100729403 Fbxo21; LOW QUALITY PROTEIN: F-box only protein 21\tK10301 FBXO21; F-box protein 21"
					},
					{
						"name":"100731256 Fbxo22; F-box only protein 22\tK10302 FBXO22; F-box protein 22"
					},
					{
						"name":"100732494 Tspan17; tetraspanin-17\tK10303 FBXO23; F-box protein 23"
					},
					{
						"name":"100713746 Fbxo24; F-box only protein 24\tK10304 FBXO24; F-box protein 24"
					},
					{
						"name":"100712791 F-box only protein 25-like\tK10305 FBXO25_32; F-box protein 25\/32"
					},
					{
						"name":"100717515 Fbxo25; F-box only protein 25 isoform X1\tK10305 FBXO25_32; F-box protein 25\/32"
					},
					{
						"name":"100726187 Fbxo32; F-box only protein 32\tK10305 FBXO25_32; F-box protein 25\/32"
					},
					{
						"name":"100730901 Fbxo27; F-box only protein 27\tK10102 FBXO27; F-box protein 27"
					},
					{
						"name":"100735209 Fbxo28; F-box only protein 28\tK10306 FBXO28; F-box protein 28"
					},
					{
						"name":"100731917 Fbxo30; F-box only protein 30 isoform X1\tK10307 FBXO30; F-box protein 30"
					},
					{
						"name":"100726050 Fbxo31; F-box only protein 31 isoform X2\tK10308 FBXO31; F-box protein 31"
					},
					{
						"name":"100733517 Fbxo33; F-box only protein 33\tK10310 FBXO33; F-box protein 33"
					},
					{
						"name":"100726302 Fbxo34; F-box only protein 34\tK10311 FBXO34; F-box protein 34"
					},
					{
						"name":"100729109 Fbxo36; F-box only protein 36 isoform X2\tK10312 FBXO36; F-box protein 36"
					},
					{
						"name":"100722381 Fbxo38; F-box only protein 38 isoform X1\tK10313 FBXO38; F-box protein 38"
					},
					{
						"name":"100725201 Fbxo39; F-box only protein 39\tK10314 FBXO39; F-box protein 39"
					},
					{
						"name":"100722717 Fbxo40; F-box only protein 40 isoform X1\tK10315 FBXO40; F-box protein 40"
					},
					{
						"name":"100717269 Fbxo41; F-box only protein 41\tK10316 FBXO41; F-box protein 41"
					},
					{
						"name":"100730465 Fbxo42; F-box only protein 42 isoform X1\tK10317 FBXO42; F-box protein 42"
					},
					{
						"name":"100732450 Fbxo43; F-box only protein 43\tK10318 FBXO43; F-box protein 43"
					},
					{
						"name":"100717006 F-box only protein 44 isoform X2\tK10103 FBXO44; F-box protein 44"
					},
					{
						"name":"100714245 Fbxo45; F-box\/SPRY domain-containing protein 1\tK10319 FBXO45; F-box protein 45"
					},
					{
						"name":"100712984 Fbxo46; F-box only protein 46\tK10320 FBXO46; F-box protein 46"
					},
					{
						"name":"100726545 Fbxo47; F-box only protein 47\tK10321 FBXO47; F-box protein 47"
					},
					{
						"name":"100729902 Fbxo48; F-box only protein 48\tK27313 FBXO48; F-box protein 48"
					}
					]
				}
				]
			},
			{
				"name":"Cul2 complex",
				"children":[
				{
					"name":"Ring finger protein",
					"children":[
					{
						"name":"100714763 Rbx1; E3 ubiquitin-protein ligase RBX1\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
					}
					]
				},
				{
					"name":"Cullin",
					"children":[
					{
						"name":"100720235 Cul2; cullin-2\tK03870 CUL2; cullin 2"
					}
					]
				},
				{
					"name":"Adoptor protein",
					"children":[
					{
						"name":"100729701 Eloc; elongin-C\tK03872 ELOC; elongin-C"
					},
					{
						"name":"100713146 Elob; elongin-B\tK03873 ELOB; elongin-B"
					},
					{
						"name":"100724128 LOW QUALITY PROTEIN: uncharacterized protein LOC100724128\tK03873 ELOB; elongin-B"
					}
					]
				},
				{
					"name":"Target recognizing subunit",
					"children":[
					{
						"name":"100729230 Vhl; von Hippel-Lindau disease tumor suppressor\tK03871 VHL; von Hippel-Lindau disease tumor supressor"
					},
					{
						"name":"100719517 Lrr1; leucine-rich repeat protein 1 isoform X2\tK10348 LRR1; LRR-repeat protein 1"
					},
					{
						"name":"100720005 Fem1a; protein fem-1 homolog A\tK25805 FEM1A_C; protein fem-1 homolog A\/C"
					},
					{
						"name":"100733293 Fem1b; protein fem-1 homolog B\tK10349 FEM1B; protein fem-1 homolog B"
					},
					{
						"name":"100731836 Appbp2; amyloid protein-binding protein 2\tK25806 APPBP2; amyloid protein-binding protein 2"
					},
					{
						"name":"100719793 Klhdc2; kelch domain-containing protein 2\tK25807 KLHDC2; kelch domain-containing protein 2"
					},
					{
						"name":"100735115 Klhdc3; kelch domain-containing protein 3\tK25808 KLHDC3; kelch domain-containing protein 3"
					},
					{
						"name":"100734463 Klhdc10; kelch domain-containing protein 10\tK25809 KLHDC10; kelch domain-containing protein 10"
					},
					{
						"name":"100729084 Zer1; protein zer-1 homolog isoform X1\tK10350 ZYG11; Zyg-11 protein"
					},
					{
						"name":"100730415 Zyg11b; protein zyg-11 homolog B\tK10350 ZYG11; Zyg-11 protein"
					},
					{
						"name":"100730692 Zyg11a; protein zyg-11 homolog A\tK10350 ZYG11; Zyg-11 protein"
					},
					{
						"name":"100721542 Zswim8; zinc finger SWIM domain-containing protein 8 isoform X3\tK25207 ZSWIM8; zinc finger SWIM domain-containing protein 8"
					},
					{
						"name":"100731688 Prame; melanoma antigen preferentially expressed in tumors\tK28155 PRAME; melanoma antigen preferentially expressed in tumors"
					}
					]
				}
				]
			},
			{
				"name":"Cul3 complex",
				"children":[
				{
					"name":"Ring finger protein",
					"children":[
					{
						"name":"100714763 Rbx1; E3 ubiquitin-protein ligase RBX1\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
					}
					]
				},
				{
					"name":"Cullin",
					"children":[
					{
						"name":"100729326 Cul3; cullin-3\tK03869 CUL3; cullin 3"
					}
					]
				},
				{
					"name":"Adoptor and target recognizing subunit (BTB)",
					"children":[
					{
						"name":"100714214 Klhl5; kelch-like protein 5 isoform X1\tK10442 KLHL1_4_5; kelch-like protein 1\/4\/5"
					},
					{
						"name":"100727502 Klhl4; LOW QUALITY PROTEIN: kelch-like protein 4\tK10442 KLHL1_4_5; kelch-like protein 1\/4\/5"
					},
					{
						"name":"100733637 Klhl1; kelch-like protein 1\tK10442 KLHL1_4_5; kelch-like protein 1\/4\/5"
					},
					{
						"name":"100723332 Klhl2; kelch-like protein 2 isoform X1\tK10443 KLHL2_3; kelch-like protein 2\/3"
					},
					{
						"name":"100732587 Klhl3; kelch-like protein 3 isoform X1\tK10443 KLHL2_3; kelch-like protein 2\/3"
					},
					{
						"name":"106025059 Klhl6; kelch-like protein 6\tK10444 KLHL6; kelch-like protein 6"
					},
					{
						"name":"100720424 Klhl7; LOW QUALITY PROTEIN: kelch-like protein 7\tK10445 KLHL7; kelch-like protein 7"
					},
					{
						"name":"100713282 Klhl8; kelch-like protein 8\tK10446 KLHL8; kelch-like protein 8"
					},
					{
						"name":"100729771 Klhl9; kelch-like protein 9\tK10447 KLHL9_13; kelch-like protein 9\/13"
					},
					{
						"name":"100735912 Klhl13; kelch-like protein 13 isoform X4\tK10447 KLHL9_13; kelch-like protein 9\/13"
					},
					{
						"name":"100714380 Klhl10; kelch-like protein 10\tK10448 KLHL10; kelch-like protein 10"
					},
					{
						"name":"100714656 Klhl11; kelch-like protein 11\tK10449 KLHL11; kelch-like protein 11"
					},
					{
						"name":"100729002 Klhl12; kelch-like protein 12\tK10450 KLHL12; kelch-like protein 12"
					},
					{
						"name":"100714868 Klhl14; kelch-like protein 14\tK10451 KLHL14; kelch-like protein 14"
					},
					{
						"name":"100716062 Klhl15; kelch-like protein 15\tK10452 KLHL15; kelch-like protein 15"
					},
					{
						"name":"100726340 Gan; gigaxonin isoform X1\tK10453 KLHL16; kelch-like protein 16 (gigaxonin)"
					},
					{
						"name":"100731883 Klhl17; kelch-like protein 17 isoform X2\tK10454 KLHL17; kelch-like protein 17 (actinfilin)"
					},
					{
						"name":"100719909 Klhl18; kelch-like protein 18 isoform X2\tK10455 KLHL18; kelch-like protein 18"
					},
					{
						"name":"100713871 Keap1; kelch-like ECH-associated protein 1\tK10456 KLHL19; kelch-like protein 19"
					},
					{
						"name":"100731038 Klhl20; kelch-like protein 20 isoform X1\tK10457 KLHL20; kelch-like protein 20"
					},
					{
						"name":"100723736 Klhl21; LOW QUALITY PROTEIN: kelch-like protein 21\tK10458 KLHL21; kelch-like protein 21"
					},
					{
						"name":"100725427 Klhl22; kelch-like protein 22\tK10459 KLHL22; kelch-like protein 22"
					},
					{
						"name":"100731969 kelch-like protein 23\tK10460 KLHL23; kelch-like protein 23"
					},
					{
						"name":"100722021 Klhl24; kelch-like protein 24\tK10461 KLHL24_35; kelch-like protein 24\/35"
					},
					{
						"name":"100731525 kelch-like protein 35\tK10461 KLHL24_35; kelch-like protein 24\/35"
					},
					{
						"name":"100732319 Klhl25; kelch-like protein 25\tK10462 KLHL25_37; kelch-like protein 25\/37 (ectoderm-neural cortex protein)"
					},
					{
						"name":"100734200 Enc1; ectoderm-neural cortex protein 1\tK10462 KLHL25_37; kelch-like protein 25\/37 (ectoderm-neural cortex protein)"
					},
					{
						"name":"100713072 Klhl26; kelch-like protein 26 isoform X1\tK10463 KLHL26; kelch-like protein 26"
					},
					{
						"name":"100734485 Ipp; actin-binding protein IPP isoform X1\tK13956 IPP; actin-binding protein IPP"
					},
					{
						"name":"100713474 Klhl28; kelch-like protein 28\tK10464 KLHL28; kelch-like protein 28"
					},
					{
						"name":"100729554 Klhl29; kelch-like protein 29 isoform X2\tK10465 KLHL29; kelch-like protein 29"
					},
					{
						"name":"100714415 Klhl30; kelch-like protein 30 isoform X2\tK10466 KLHL30; kelch-like protein 30"
					},
					{
						"name":"100719309 Klhl31; LOW QUALITY PROTEIN: kelch-like protein 31\tK10467 KLHL31; kelch-like protein 31"
					},
					{
						"name":"100720606 Klhl32; kelch-like protein 32 isoform X1\tK10468 KLHL32; kelch-like protein 32"
					},
					{
						"name":"100719621 Klhl33; kelch-like protein 33 isoform X1\tK13957 KLHL33; kelch-like protein 33"
					},
					{
						"name":"100713352 Klhl34; kelch-like protein 34\tK10469 KLHL34; kelch-like protein 34"
					},
					{
						"name":"100716766 Klhl36; kelch-like protein 36\tK13958 KLHL36; kelch-like protein 36"
					},
					{
						"name":"100735450 Klhl38; kelch-like protein 38\tK13959 KLHL38; kelch-like protein 38"
					},
					{
						"name":"100723627 Klhl42; LOW QUALITY PROTEIN: kelch-like protein 42\tK27973 KLHL42; kelch-like protein 42"
					},
					{
						"name":"100721706 Kbtbd2; kelch repeat and BTB domain-containing protein 2\tK10470 KBTBD2; kelch repeat and BTB domain-containing protein 2"
					},
					{
						"name":"100729929 Kbtbd3; kelch repeat and BTB domain-containing protein 3 isoform X1\tK10471 KBTBD3; kelch repeat and BTB domain-containing protein 3"
					},
					{
						"name":"100728212 Kbtbd4; kelch repeat and BTB domain-containing protein 4\tK10472 KBTBD4; kelch repeat and BTB domain-containing protein 4"
					},
					{
						"name":"100733725 Klhl40; kelch-like protein 40\tK10473 KBTBD5_10; kelch repeat and BTB domain-containing protein 5\/10"
					},
					{
						"name":"100735323 Klhl41; kelch-like protein 41\tK10473 KBTBD5_10; kelch repeat and BTB domain-containing protein 5\/10"
					},
					{
						"name":"100730225 LOW QUALITY PROTEIN: kelch repeat and BTB domain-containing protein 7\tK10474 KBTBD6_7; kelch repeat and BTB domain-containing protein 6\/7"
					},
					{
						"name":"100719798 Kbtbd8; LOW QUALITY PROTEIN: kelch repeat and BTB domain-containing protein 8\tK10475 KBTBD8; kelch repeat and BTB domain-containing protein 8"
					},
					{
						"name":"101787268 Kbtbd11; LOW QUALITY PROTEIN: kelch repeat and BTB domain-containing protein 11\tK10476 KBTBD11; kelch repeat and BTB domain-containing protein 11"
					},
					{
						"name":"100720473 Kbtbd12; kelch repeat and BTB domain-containing protein 12 isoform X1\tK21912 KBTBD12; kelch repeat and BTB domain-containing protein 12"
					},
					{
						"name":"100713869 kelch repeat and BTB domain-containing protein 13\tK21913 KBTBD13; kelch repeat and BTB domain-containing protein 13"
					},
					{
						"name":"100727533 kelch repeat and BTB domain-containing protein 13-like\tK21913 KBTBD13; kelch repeat and BTB domain-containing protein 13"
					},
					{
						"name":"100712774 Btbd2; LOW QUALITY PROTEIN: BTB\/POZ domain-containing protein 2\tK10477 BTBD1_2; BTB\/POZ domain-containing protein 1\/2"
					},
					{
						"name":"100724778 Btbd1; BTB\/POZ domain-containing protein 1\tK10477 BTBD1_2; BTB\/POZ domain-containing protein 1\/2"
					},
					{
						"name":"100716222 Btbd6; LOW QUALITY PROTEIN: BTB\/POZ domain-containing protein 6\tK10478 BTBD3_6; BTB\/POZ domain-containing protein 3\/6"
					},
					{
						"name":"100720645 Btbd3; BTB\/POZ domain-containing protein 3 isoform X1\tK10478 BTBD3_6; BTB\/POZ domain-containing protein 3\/6"
					},
					{
						"name":"100716596 Btbd7; BTB\/POZ domain-containing protein 7 isoform X1\tK10479 BTBD7; BTB\/POZ domain-containing protein 7"
					},
					{
						"name":"100720203 uncharacterized protein KIAA1107 homolog isoform X1\tK10480 BTBD8; BTB\/POZ domain-containing protein 8"
					},
					{
						"name":"100721629 Btbd9; BTB\/POZ domain-containing protein 9\tK10481 BTBD9; BTB\/POZ domain-containing protein 9"
					},
					{
						"name":"100713347 Btbd10; BTB\/POZ domain-containing protein 10 isoform X2\tK10482 BTBD10; BTB\/POZ domain-containing protein 10"
					},
					{
						"name":"100714346 Btbd11; LOW QUALITY PROTEIN: ankyrin repeat and BTB\/POZ domain-containing protein BTBD11\tK10483 BTBD11; BTB\/POZ domain-containing protein 11"
					},
					{
						"name":"100718161 Slx4; structure-specific endonuclease subunit SLX4 isoform X2\tK10484 BTBD12; structure-specific endonuclease subunit SLX4 (BTB\/POZ domain-containing protein 12)"
					},
					{
						"name":"100719411 Gmcl1; germ cell-less protein-like 1 isoform X1\tK10485 BTBD13; BTB\/POZ domain-containing protein 13 (germ cell-less protein-like 1)"
					},
					{
						"name":"100726549 Nacc1; nucleus accumbens-associated protein 1 isoform X2\tK10486 BTBD14; BTB\/POZ domain-containing protein 14"
					},
					{
						"name":"100735564 Nacc2; nucleus accumbens-associated protein 2\tK10486 BTBD14; BTB\/POZ domain-containing protein 14"
					},
					{
						"name":"100716512 Btbd16; BTB\/POZ domain-containing protein 16\tK10487 BTBD16; BTB\/POZ domain-containing protein 16"
					},
					{
						"name":"100713112 Zbtb1; zinc finger and BTB domain-containing protein 1 isoform X1\tK10488 ZBTB1; zinc finger and BTB domain-containing protein 1"
					},
					{
						"name":"100724645 Zbtb2; zinc finger and BTB domain-containing protein 2\tK10489 ZBTB2; zinc finger and BTB domain-containing protein 2"
					},
					{
						"name":"100733681 Zbtb3; zinc finger and BTB domain-containing protein 3\tK10490 ZBTB3; zinc finger and BTB domain-containing protein 3"
					},
					{
						"name":"100713820 Zbtb4; zinc finger and BTB domain-containing protein 4\tK10491 ZBTB4; zinc finger and BTB domain-containing protein 4"
					},
					{
						"name":"100713378 Zbtb5; LOW QUALITY PROTEIN: zinc finger and BTB domain-containing protein 5\tK10492 ZBTB5; zinc finger and BTB domain-containing protein 5"
					},
					{
						"name":"100713377 Zbtb6; zinc finger and BTB domain-containing protein 6\tK10493 ZBTB6; zinc finger and BTB domain-containing protein 6"
					},
					{
						"name":"100726674 Zbtb7c; zinc finger and BTB domain-containing protein 7C\tK10494 ZBTB7; zinc finger and BTB domain-containing protein 7"
					},
					{
						"name":"100729401 Zbtb7a; zinc finger and BTB domain-containing protein 7A\tK10494 ZBTB7; zinc finger and BTB domain-containing protein 7"
					},
					{
						"name":"100735855 Zbtb7b; zinc finger and BTB domain-containing protein 7B\tK10494 ZBTB7; zinc finger and BTB domain-containing protein 7"
					},
					{
						"name":"100726759 Zbtb8a; zinc finger and BTB domain-containing protein 8A isoform X1\tK10495 ZBTB8; zinc finger and BTB domain-containing protein 8"
					},
					{
						"name":"100728711 Zbtb8b; zinc finger and BTB domain-containing protein 8B\tK10495 ZBTB8; zinc finger and BTB domain-containing protein 8"
					},
					{
						"name":"100729465 Zbtb9; zinc finger and BTB domain-containing protein 9 isoform X1\tK10496 ZBTB9; zinc finger and BTB domain-containing protein 9"
					},
					{
						"name":"100725271 Zbtb10; zinc finger and BTB domain-containing protein 10\tK10497 ZBTB10; zinc finger and BTB domain-containing protein 10"
					},
					{
						"name":"100736114 Zbtb11; zinc finger and BTB domain-containing protein 11\tK10498 ZBTB11; zinc finger and BTB domain-containing protein 11"
					},
					{
						"name":"106028490 Zbtb12; zinc finger and BTB domain-containing protein 12\tK10499 ZBTB12; zinc finger and BTB domain-containing protein 12"
					},
					{
						"name":"100732029 Zbtb16; zinc finger and BTB domain-containing protein 16\tK10055 ZBTB16; zinc finger and BTB domain-containing protein 16"
					},
					{
						"name":"100731568 Zbtb17; zinc finger and BTB domain-containing protein 17\tK10500 ZBTB17; zinc finger and BTB domain-containing protein 17"
					},
					{
						"name":"100716912 Zbtb20; zinc finger and BTB domain-containing protein 20\tK10501 ZBTB20; zinc finger and BTB domain-containing protein 20"
					},
					{
						"name":"100730284 Zbtb22; zinc finger and BTB domain-containing protein 22\tK10502 ZBTB22; zinc finger and BTB domain-containing protein 22"
					},
					{
						"name":"100715579 Zbtb24; zinc finger and BTB domain-containing protein 24 isoform X1\tK10503 ZBTB24; zinc finger and BTB domain-containing protein 24"
					},
					{
						"name":"100712842 Zbtb25; zinc finger and BTB domain-containing protein 25 isoform X1\tK10504 ZBTB25; zinc finger and BTB domain-containing protein 25"
					},
					{
						"name":"100731017 Zbtb26; zinc finger and BTB domain-containing protein 26\tK10505 ZBTB26; zinc finger and BTB domain-containing protein 26"
					},
					{
						"name":"100734892 Zbtb32; zinc finger and BTB domain-containing protein 32\tK10506 ZBTB32; zinc finger and BTB domain-containing protein 32"
					},
					{
						"name":"100713178 Zbtb33; transcriptional regulator Kaiso\tK10507 ZBTB33; zinc finger and BTB domain-containing protein 33"
					},
					{
						"name":"100727675 Zbtb34; zinc finger and BTB domain-containing protein 34\tK10508 ZBTB34; zinc finger and BTB domain-containing protein 34"
					},
					{
						"name":"100724774 Zbtb37; zinc finger and BTB domain-containing protein 37\tK10509 ZBTB37; zinc finger and BTB domain-containing protein 37"
					},
					{
						"name":"100734466 Zbtb38; zinc finger and BTB domain-containing protein 38\tK10510 ZBTB38; zinc finger and BTB domain-containing protein 38"
					},
					{
						"name":"100727707 Zbtb39; zinc finger and BTB domain-containing protein 39\tK10511 ZBTB39; zinc finger and BTB domain-containing protein 39"
					},
					{
						"name":"100716645 Zbtb40; zinc finger and BTB domain-containing protein 40 isoform X1\tK10512 ZBTB40; zinc finger and BTB domain-containing protein 40"
					},
					{
						"name":"100732771 Zbtb41; zinc finger and BTB domain-containing protein 41\tK10513 ZBTB41; zinc finger and BTB domain-containing protein 41"
					},
					{
						"name":"100727951 Zbtb43; zinc finger and BTB domain-containing protein 43 isoform X2\tK10514 ZBTB43; zinc finger and BTB domain-containing protein 43"
					},
					{
						"name":"100713204 Zbtb44; zinc finger and BTB domain-containing protein 44 isoform X1\tK10515 ZBTB44; zinc finger and BTB domain-containing protein 44"
					},
					{
						"name":"100727932 Zbtb45; zinc finger and BTB domain-containing protein 45\tK10516 ZBTB45; zinc finger and BTB domain-containing protein 45"
					},
					{
						"name":"100729315 Zbtb46; zinc finger and BTB domain-containing protein 46\tK10517 ZBTB46; zinc finger and BTB domain-containing protein 46"
					},
					{
						"name":"100712770 Zbtb47; zinc finger and BTB domain-containing protein 47 isoform X2\tK10518 ZBTB47; zinc finger and BTB domain-containing protein 47"
					},
					{
						"name":"100724022 Zbtb48; telomere zinc finger-associated protein\tK10519 ZBTB48; zinc finger and BTB domain-containing protein 48"
					},
					{
						"name":"100720193 Abtb1; ankyrin repeat and BTB\/POZ domain-containing protein 1\tK10520 ABTB1; ankyrin repeat and BTB\/POZ domain-containing protein 1"
					},
					{
						"name":"100732805 Abtb2; ankyrin repeat and BTB\/POZ domain-containing protein 2\tK10521 ABTB2; ankyrin repeat and BTB\/POZ domain-containing protein 2"
					},
					{
						"name":"100712847 Rhobtb1; rho-related BTB domain-containing protein 1 isoform X3\tK07868 RHOBTB1_2; Rho-related BTB domain-containing protein 1\/2"
					},
					{
						"name":"100729421 Rhobtb2; rho-related BTB domain-containing protein 2\tK07868 RHOBTB1_2; Rho-related BTB domain-containing protein 1\/2"
					},
					{
						"name":"100720394 Rhobtb3; rho-related BTB domain-containing protein 3\tK07869 RHOBTB3; Rho-related BTB domain-containing protein 3"
					},
					{
						"name":"100718718 Kctd10; BTB\/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 isoform X1\tK15074 BACURD; BTB\/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein"
					},
					{
						"name":"100728236 Tnfaip1; BTB\/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2\tK15074 BACURD; BTB\/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein"
					},
					{
						"name":"100732787 Kctd13; LOW QUALITY PROTEIN: BTB\/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1\tK15074 BACURD; BTB\/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein"
					},
					{
						"name":"100715060 Kctd1; BTB\/POZ domain-containing protein KCTD1 isoform X2\tK21754 KCTD1_15; BTB\/POZ domain-containing protein KCTD1\/15"
					},
					{
						"name":"100721595 Kctd15; BTB\/POZ domain-containing protein KCTD15\tK21754 KCTD1_15; BTB\/POZ domain-containing protein KCTD1\/15"
					},
					{
						"name":"100724818 Kctd2; LOW QUALITY PROTEIN: BTB\/POZ domain-containing protein KCTD2\tK21914 KCTD2_5_17; BTB\/POZ domain-containing protein KCTD2\/5\/17"
					},
					{
						"name":"100730087 Kctd17; LOW QUALITY PROTEIN: BTB\/POZ domain-containing protein KCTD17\tK21914 KCTD2_5_17; BTB\/POZ domain-containing protein KCTD2\/5\/17"
					},
					{
						"name":"100735697 Kctd5; BTB\/POZ domain-containing protein KCTD5\tK21914 KCTD2_5_17; BTB\/POZ domain-containing protein KCTD2\/5\/17"
					},
					{
						"name":"100719894 Kctd3; BTB\/POZ domain-containing protein KCTD3 isoform X1\tK21915 KCTD3; BTB\/POZ domain-containing protein KCTD3"
					},
					{
						"name":"100733757 Kctd6; BTB\/POZ domain-containing protein KCTD6\tK21916 KCTD6; BTB\/POZ domain-containing protein KCTD6"
					},
					{
						"name":"100733217 Kctd14; BTB\/POZ domain-containing protein KCTD14\tK21917 KCTD7_14; BTB\/POZ domain-containing protein KCTD7\/14"
					},
					{
						"name":"101788016 Kctd7; BTB\/POZ domain-containing protein KCTD7 isoform X3\tK21917 KCTD7_14; BTB\/POZ domain-containing protein KCTD7\/14"
					},
					{
						"name":"100719700 Kctd8; BTB\/POZ domain-containing protein KCTD8\tK21918 KCTD8_12_16; BTB\/POZ domain-containing protein KCTD8\/12\/16"
					},
					{
						"name":"100731603 Kctd16; BTB\/POZ domain-containing protein KCTD16\tK21918 KCTD8_12_16; BTB\/POZ domain-containing protein KCTD8\/12\/16"
					},
					{
						"name":"101787203 Kctd12; LOW QUALITY PROTEIN: BTB\/POZ domain-containing protein KCTD12\tK21918 KCTD8_12_16; BTB\/POZ domain-containing protein KCTD8\/12\/16"
					},
					{
						"name":"100732066 Kctd9; BTB\/POZ domain-containing protein KCTD9 isoform X1\tK21919 KCTD9; BTB\/POZ domain-containing protein KCTD9"
					},
					{
						"name":"100736188 Kctd11; BTB\/POZ domain-containing protein KCTD11\tK21920 KCTD11; BTB\/POZ domain-containing protein KCTD11 [EC:2.3.2.27]"
					},
					{
						"name":"100720762 Kctd18; BTB\/POZ domain-containing protein KCTD18 isoform X2\tK21921 KCTD18; BTB\/POZ domain-containing protein KCTD18"
					},
					{
						"name":"100735642 Kctd21; BTB\/POZ domain-containing protein KCTD21\tK21922 KCTD21; BTB\/POZ domain-containing protein KCTD21"
					},
					{
						"name":"100724526 Diablo; diablo homolog, mitochondrial\tK10522 DIABLO; diablo"
					},
					{
						"name":"100713182 Spop; speckle-type POZ protein\tK10523 SPOP; speckle-type POZ protein"
					},
					{
						"name":"100730410 Spopl; speckle-type POZ protein-like\tK10523 SPOP; speckle-type POZ protein"
					},
					{
						"name":"100724888 Lztr1; leucine-zipper-like transcriptional regulator 1\tK23330 LZTR1; leucine-zipper-like transcriptional regulator 1"
					}
					]
				}
				]
			},
			{
				"name":"Cul4 complex",
				"children":[
				{
					"name":"Ring finger protein",
					"children":[
					{
						"name":"100714763 Rbx1; E3 ubiquitin-protein ligase RBX1\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
					}
					]
				},
				{
					"name":"Cullin",
					"children":[
					{
						"name":"100714185 Cul4b; cullin-4B isoform X1\tK10609 CUL4; cullin 4"
					},
					{
						"name":"100736154 Cul4a; cullin-4A\tK10609 CUL4; cullin 4"
					}
					]
				},
				{
					"name":"Adoptor protein",
					"children":[
					{
						"name":"100724177 Ddb1; DNA damage-binding protein 1\tK10610 DDB1; DNA damage-binding protein 1"
					}
					]
				},
				{
					"name":"Target recognizing subunit (DCAF)",
					"children":[
					{
						"name":"100726538 Ddb2; DNA damage-binding protein 2 isoform X1\tK10140 DDB2; DNA damage-binding protein 2"
					},
					{
						"name":"100720574 Ercc8; DNA excision repair protein ERCC-8 isoform X1\tK10570 ERCC8; DNA excision repair protein ERCC-8"
					},
					{
						"name":"100732872 Det1; DET1 homolog isoform X1\tK10571 DET1; de-etiolated-1"
					},
					{
						"name":"100728351 Cop1; E3 ubiquitin-protein ligase RFWD2\tK10143 RFWD2; E3 ubiquitin-protein ligase RFWD2 [EC:2.3.2.27]"
					},
					{
						"name":"100732730 Dda1; DET1- and DDB1-associated protein 1 isoform X1\tK11792 DDA1; DET1- and DDB1-associated protein 1"
					},
					{
						"name":"100735293 Crbn; protein cereblon isoform X1\tK11793 CRBN; cereblon"
					},
					{
						"name":"100733718 torsin-1A-interacting protein 2\tK11794 IFRG15; IFRG15 protein"
					},
					{
						"name":"100712636 Trpc4ap; short transient receptor potential channel 4-associated protein isoform X2\tK11796 TRPC4AP; Trpc4-associated protein"
					},
					{
						"name":"100734659 Dcaf1; LOW QUALITY PROTEIN: DDB1- and CUL4-associated factor 1\tK11789 DCAF1; DDB1- and CUL4-associated factor 1 [EC:2.7.11.1]"
					},
					{
						"name":"100723475 Dtl; denticleless protein homolog\tK11790 DTL; denticleless"
					},
					{
						"name":"100726951 Dcaf4; DDB1- and CUL4-associated factor 4 isoform X1\tK11799 DCAF4; DDB1- and CUL4-associated factor 4"
					},
					{
						"name":"100713665 Dcaf5; DDB1- and CUL4-associated factor 5\tK11800 DCAF5; DDB1- and CUL4-associated factor 5"
					},
					{
						"name":"100713643 Dcaf6; DDB1- and CUL4-associated factor 6\tK11795 DCAF6; DDB1- and CUL4-associated factor 6"
					},
					{
						"name":"100715499 Dcaf7; DDB1- and CUL4-associated factor 7\tK11805 DCAF7; DDB1- and CUL4-associated factor 7"
					},
					{
						"name":"100730616 Dcaf8; DDB1- and CUL4-associated factor 8\tK11804 DCAF8; DDB1- and CUL4-associated factor 8"
					},
					{
						"name":"100725211 Wdtc1; WD and tetratricopeptide repeats protein 1\tK11807 WDTC1; WD and tetratricopeptide repeats protein 1"
					},
					{
						"name":"100714765 Dcaf10; DDB1- and CUL4-associated factor 10\tK11802 DCAF10; DDB1- and CUL4-associated factor 10"
					},
					{
						"name":"100714230 Dcaf11; DDB1- and CUL4-associated factor 11 isoform X2\tK11801 DCAF11; DDB1- and CUL4-associated factor 11"
					},
					{
						"name":"100720707 Dcaf12; DDB1- and CUL4-associated factor 12 isoform X1\tK11803 DCAF12; DDB1- and CUL4-associated factor 12"
					},
					{
						"name":"100722879 DDB1- and CUL4-associated factor 12-like protein 2\tK11803 DCAF12; DDB1- and CUL4-associated factor 12"
					},
					{
						"name":"100726599 DDB1- and CUL4-associated factor 12-like protein 2\tK11803 DCAF12; DDB1- and CUL4-associated factor 12"
					},
					{
						"name":"101788347 DDB1- and CUL4-associated factor 12-like protein 2\tK11803 DCAF12; DDB1- and CUL4-associated factor 12"
					},
					{
						"name":"100718458 Dcaf13; DDB1- and CUL4-associated factor 13\tK11806 DCAF13; DDB1- and CUL4-associated factor 13"
					},
					{
						"name":"100718997 Phip; PH-interacting protein\tK11797 PHIP; PH-interacting protein"
					},
					{
						"name":"100723912 Dcaf15; DDB1- and CUL4-associated factor 15\tK11791 DCAF15; DDB1- and CUL4-associated factor 15"
					},
					{
						"name":"101788432 Dcaf16; LOW QUALITY PROTEIN: DDB1- and CUL4-associated factor 16\tK23626 DCAF16; DDB1- and CUL4-associated factor 16"
					},
					{
						"name":"100724246 Dcaf17; DDB1- and CUL4-associated factor 17 isoform X1\tK23331 DCAF17; DDB1- and CUL4-associated factor 17"
					},
					{
						"name":"100713169 Brwd1; bromodomain and WD repeat-containing protein 1\tK11798 BRWD1_3; bromodomain and WD repeat domain containing protein 1\/3"
					},
					{
						"name":"100733885 Brwd3; bromodomain and WD repeat-containing protein 3\tK11798 BRWD1_3; bromodomain and WD repeat domain containing protein 1\/3"
					},
					{
						"name":"100734086 Wdr26; WD repeat-containing protein 26 isoform X4\tK22382 WDR26; WD repeat-containing protein 26"
					},
					{
						"name":"100735925 Wdr70; WD repeat-containing protein 70 isoform X1\tK24752 WDR70; WD repeat-containing protein 70"
					},
					{
						"name":"100718975 Wdr76; WD repeat-containing protein 76 isoform X1\tK24755 WDR76; WD repeat-containing protein 76"
					}
					]
				}
				]
			},
			{
				"name":"Cul5 complex",
				"children":[
				{
					"name":"Ring finger protein",
					"children":[
					{
						"name":"100735307 Rnf7; RING-box protein 2 isoform X2\tK10611 RBX2; RING-box protein 2"
					}
					]
				},
				{
					"name":"Cullin",
					"children":[
					{
						"name":"100717146 Cul5; cullin-5\tK10612 CUL5; cullin 5"
					}
					]
				},
				{
					"name":"Adoptor protein",
					"children":[
					{
						"name":"100729701 Eloc; elongin-C\tK03872 ELOC; elongin-C"
					},
					{
						"name":"100713146 Elob; elongin-B\tK03873 ELOB; elongin-B"
					},
					{
						"name":"100724128 LOW QUALITY PROTEIN: uncharacterized protein LOC100724128\tK03873 ELOB; elongin-B"
					}
					]
				},
				{
					"name":"Target recognizing subunit",
					"children":[
					{
						"name":"100719354 Cish; cytokine-inducible SH2-containing protein isoform X1\tK04701 CISH; cytokine inducible SH2-containing protein"
					},
					{
						"name":"100728652 Socs1; suppressor of cytokine signaling 1\tK04694 SOCS1; suppressor of cytokine signaling 1"
					},
					{
						"name":"100725088 Socs3; suppressor of cytokine signaling 3\tK04696 SOCS3; suppressor of cytokine signaling 3"
					},
					{
						"name":"100735753 Socs4; suppressor of cytokine signaling 4\tK04697 SOCS4; suppressor of cytokine signaling 4"
					},
					{
						"name":"100722912 Socs5; suppressor of cytokine signaling 5\tK04698 SOCS5; suppressor of cytokine signaling 5"
					},
					{
						"name":"100713080 Socs6; suppressor of cytokine signaling 6\tK04699 SOCS6_7; suppressor of cytokine signaling 6\/7"
					},
					{
						"name":"100724639 Socs7; LOW QUALITY PROTEIN: suppressor of cytokine signaling 7\tK04699 SOCS6_7; suppressor of cytokine signaling 6\/7"
					},
					{
						"name":"100727879 Asb1; ankyrin repeat and SOCS box protein 1 isoform X1\tK10323 ASB1; ankyrin repeat and SOCS box protein 1"
					},
					{
						"name":"100735515 Asb2; ankyrin repeat and SOCS box protein 2 isoform X1\tK10324 ASB2; ankyrin repeat and SOCS box protein 2"
					},
					{
						"name":"100716868 Asb3; ankyrin repeat and SOCS box protein 3\tK10325 ASB3; ankyrin repeat and SOCS box protein 3"
					},
					{
						"name":"100735020 Asb4; ankyrin repeat and SOCS box protein 4\tK10326 ASB4; ankyrin repeat and SOCS box protein 4"
					},
					{
						"name":"100725026 Asb5; ankyrin repeat and SOCS box protein 5 isoform X1\tK10327 ASB5; ankyrin repeat and SOCS box protein 5"
					},
					{
						"name":"100733793 Asb6; ankyrin repeat and SOCS box protein 6 isoform X1\tK10328 ASB6; ankyrin repeat and SOCS box protein 6"
					},
					{
						"name":"100713127 Asb7; ankyrin repeat and SOCS box protein 7\tK10329 ASB7; ankyrin repeat and SOCS box protein 7"
					},
					{
						"name":"100733343 Asb8; ankyrin repeat and SOCS box protein 8\tK10330 ASB8; ankyrin repeat and SOCS box protein 8"
					},
					{
						"name":"100733651 Asb9; ankyrin repeat and SOCS box protein 9\tK10331 ASB9; ankyrin repeat and SOCS box protein 9"
					},
					{
						"name":"100718113 Asb10; ankyrin repeat and SOCS box protein 10 isoform X1\tK10332 ASB10; ankyrin repeat and SOCS box protein 10"
					},
					{
						"name":"100713888 Asb11; ankyrin repeat and SOCS box protein 11 isoform X1\tK10333 ASB11; ankyrin repeat and SOCS box protein 11"
					},
					{
						"name":"100732444 Asb12; ankyrin repeat and SOCS box protein 12\tK10334 ASB12; ankyrin repeat and SOCS box protein 12"
					},
					{
						"name":"100717013 Asb13; ankyrin repeat and SOCS box protein 13\tK10335 ASB13; ankyrin repeat and SOCS box protein 13"
					},
					{
						"name":"101787593 Asb14; ankyrin repeat and SOCS box protein 14 isoform X1\tK10336 ASB14; ankyrin repeat and SOCS box protein 14"
					},
					{
						"name":"100713401 Asb15; ankyrin repeat and SOCS box protein 15\tK10337 ASB15; ankyrin repeat and SOCS box protein 15"
					},
					{
						"name":"100722521 Asb16; LOW QUALITY PROTEIN: ankyrin repeat and SOCS box protein 16\tK10338 ASB16; ankyrin repeat and SOCS box protein 16"
					},
					{
						"name":"100716031 Asb17; ankyrin repeat and SOCS box protein 17\tK10339 ASB17; ankyrin repeat and SOCS box protein 17"
					},
					{
						"name":"100717207 Asb18; LOW QUALITY PROTEIN: ankyrin repeat and SOCS box protein 18\tK10340 ASB18; ankyrin repeat and SOCS box protein 18"
					},
					{
						"name":"100729636 Wsb1; WD repeat and SOCS box-containing protein 1 isoform X1\tK10341 WSB1; WD repeat and SOCS box-containing protein 1"
					},
					{
						"name":"100731887 Wsb2; WD repeat and SOCS box-containing protein 2\tK10342 WSB2; WD repeat and SOCS box-containing protein 2"
					},
					{
						"name":"100721617 Spsb1; SPRY domain-containing SOCS box protein 1 isoform X2\tK10343 SPSB1_4; SPRY domain-containing SOCS box protein 1\/4"
					},
					{
						"name":"100734187 Spsb4; SPRY domain-containing SOCS box protein 4\tK10343 SPSB1_4; SPRY domain-containing SOCS box protein 1\/4"
					},
					{
						"name":"100724255 Spsb2; SPRY domain-containing SOCS box protein 2 isoform X1\tK10344 SPSB2; SPRY domain-containing SOCS box protein 2"
					},
					{
						"name":"100727903 Spsb3; SPRY domain-containing SOCS box protein 3 isoform X2\tK10345 SPSB3; SPRY domain-containing SOCS box protein 3"
					},
					{
						"name":"100715088 Rab40c; ras-related protein Rab-40C\tK07928 RAB40; Ras-related protein Rab-40"
					},
					{
						"name":"100717623 Rab40b; ras-related protein Rab-40B\tK07928 RAB40; Ras-related protein Rab-40"
					},
					{
						"name":"100732997 Lrrc41; leucine-rich repeat-containing protein 41 isoform X1\tK10347 LRRC41; leucine-rich repeat-containing protein 41"
					},
					{
						"name":"100724764 Rspry1; RING finger and SPRY domain-containing protein 1 isoform X1\tK23332 RSPRY1; RING finger and SPRY domain-containing protein 1"
					},
					{
						"name":"100733932 Ankrd9; ankyrin repeat domain-containing protein 9\tK25208 ANKRD9; ankyrin repeat domain-containing protein 9"
					},
					{
						"name":"100725582 Klhdc1; kelch domain-containing protein 1 isoform X2\tK25810 KLHDC1; kelch domain-containing protein 1"
					}
					]
				}
				]
			},
			{
				"name":"Cul7 complex",
				"children":[
				{
					"name":"Ring finger protein",
					"children":[
					{
						"name":"100714763 Rbx1; E3 ubiquitin-protein ligase RBX1\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
					}
					]
				},
				{
					"name":"Cullin",
					"children":[
					{
						"name":"100734834 Cul7; cullin-7 isoform X1\tK10613 CUL7; cullin 7"
					}
					]
				},
				{
					"name":"Adaptor protein",
					"children":[
					{
						"name":"100135616 Skp1; S-phase kinase-associated protein 1\tK03094 SKP1; S-phase kinase-associated protein 1"
					}
					]
				},
				{
					"name":"Target recognizing subunit",
					"children":[
					{
						"name":"100728842 Fbxw8; F-box\/WD repeat-containing protein 8\tK10264 FBXW8; F-box and WD-40 domain protein 8"
					}
					]
				}
				]
			},
			{
				"name":"Cul8 complex",
				"children":[
				{
					"name":"Ring finger protein",
					"children":[
					{
						"name":"100714763 Rbx1; E3 ubiquitin-protein ligase RBX1\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
					}
					]
				},
				{
					"name":"Cullin"
				},
				{
					"name":"Adaptor protein"
				},
				{
					"name":"Target recognizing subunit"
				}
				]
			},
			{
				"name":"Cul9 complex",
				"children":[
				{
					"name":"Ring finger protein",
					"children":[
					{
						"name":"100714763 Rbx1; E3 ubiquitin-protein ligase RBX1\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
					}
					]
				},
				{
					"name":"Cullin",
					"children":[
					{
						"name":"100715714 Cul9; cullin-9 isoform X4\tK11970 CUL9; cullin 9"
					}
					]
				}
				]
			},
			{
				"name":"APC\/C",
				"children":[
				{
					"name":"Ring finger protein",
					"children":[
					{
						"name":"100734505 Anapc11; anaphase-promoting complex subunit 11\tK03358 APC11; anaphase-promoting complex subunit 11"
					}
					]
				},
				{
					"name":"Cullin",
					"children":[
					{
						"name":"100730651 Anapc2; anaphase-promoting complex subunit 2\tK03349 APC2; anaphase-promoting complex subunit 2"
					}
					]
				},
				{
					"name":"Target recognizing subunit",
					"children":[
					{
						"name":"100718545 Cdc20; cell division cycle protein 20 homolog\tK03363 CDC20; cell division cycle 20, cofactor of APC complex"
					},
					{
						"name":"100714794 Fzr1; fizzy-related protein homolog\tK03364 CDH1; cell division cycle 20-like protein 1, cofactor of APC complex"
					}
					]
				},
				{
					"name":"Other subunits",
					"children":[
					{
						"name":"100725716 Anapc1; anaphase-promoting complex subunit 1 isoform X2\tK03348 APC1; anaphase-promoting complex subunit 1"
					},
					{
						"name":"100731091 Cdc27; cell division cycle protein 27 homolog isoform X3\tK03350 APC3; anaphase-promoting complex subunit 3"
					},
					{
						"name":"100720696 Anapc4; anaphase-promoting complex subunit 4\tK03351 APC4; anaphase-promoting complex subunit 4"
					},
					{
						"name":"100726899 Anapc5; anaphase-promoting complex subunit 5 isoform X1\tK03352 APC5; anaphase-promoting complex subunit 5"
					},
					{
						"name":"100725418 Cdc16; cell division cycle protein 16 homolog isoform X2\tK03353 APC6; anaphase-promoting complex subunit 6"
					},
					{
						"name":"100716878 Anapc7; anaphase-promoting complex subunit 7\tK03354 APC7; anaphase-promoting complex subunit 7"
					},
					{
						"name":"100733068 Cdc23; cell division cycle protein 23 homolog isoform X1\tK03355 APC8; anaphase-promoting complex subunit 8"
					},
					{
						"name":"100728363 Anapc10; anaphase-promoting complex subunit 10\tK03357 APC10; anaphase-promoting complex subunit 10"
					},
					{
						"name":"100732729 Cdc26; anaphase-promoting complex subunit CDC26\tK03359 APC12; anaphase-promoting complex subunit 12"
					},
					{
						"name":"100728170 Anapc13; anaphase-promoting complex subunit 13\tK12456 APC13; anaphase-promoting complex subunit 13"
					},
					{
						"name":"100726252 Anapc15; anaphase-promoting complex subunit 15 isoform X3\tK25228 APC15; anaphase-promoting complex subunit 15"
					},
					{
						"name":"100714226 Anapc16; anaphase-promoting complex subunit 16 isoform X3\tK25229 APC16; anaphase-promoting complex subunit 16"
					}
					]
				}
				]
			},
			{
				"name":"BRCC complex",
				"children":[
				{
					"name":"100722339 Brca1; breast cancer type 1 susceptibility protein isoform X2\tK10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]"
				},
				{
					"name":"100713136 Brca2; breast cancer type 2 susceptibility protein\tK08775 BRCA2; breast cancer 2 susceptibility protein"
				},
				{
					"name":"100719736 Brcc3; lys-63-specific deubiquitinase BRCC36 isoform X1\tK11864 BRCC3; BRCA1\/BRCA2-containing complex subunit 3 [EC:3.4.19.-]"
				},
				{
					"name":"100731860 Bard1; BRCA1-associated RING domain protein 1 isoform X1\tK10683 BARD1; BRCA1-associated RING domain protein 1"
				},
				{
					"name":"100725666 Babam2; BRISC and BRCA1-A complex member 2\tK12173 BRE; BRCA1-A complex subunit BRE"
				},
				{
					"name":"100716391 Rad51; DNA repair protein RAD51 homolog 1 isoform X1\tK04482 RAD51; DNA repair protein RAD51"
				}
				]
			},
			{
				"name":"KPC complex",
				"children":[
				{
					"name":"100730766 Rnf123; E3 ubiquitin-protein ligase RNF123 isoform X2\tK12169 KPC1; Kip1 ubiquitination-promoting complex protein 1 [EC:2.3.2.27]"
				},
				{
					"name":"100722364 Ubac1; ubiquitin-associated domain-containing protein 1 isoform X1\tK12174 KPC2; Kip1 ubiquitination-promoting complex protein 2"
				}
				]
			},
			{
				"name":"LUBAC complex",
				"children":[
				{
					"name":"100713439 sharpin\tK20894 SHARPIN; shank-associated RH domain-interacting protein"
				},
				{
					"name":"100734748 Rbck1; ranBP-type and C3HC4-type zinc finger-containing protein 1\tK10630 RBCK1; RanBP-type and C3HC4-type zinc finger-containing protein 1 [EC:2.3.2.31]"
				},
				{
					"name":"100733433 Rnf31; E3 ubiquitin-protein ligase RNF31 isoform X1\tK11974 RNF31; E3 ubiquitin-protein ligase RNF31 [EC:2.3.2.31]"
				}
				]
			},
			{
				"name":"CTLH complex",
				"children":[
				{
					"name":"100726749 Rmnd5a; protein RMD5 homolog A\tK23333 RMND5; E3 ubiquitin-protein transferase RMND5 [EC:2.3.2.27]"
				},
				{
					"name":"100729497 Rmnd5b; protein RMD5 homolog B isoform X1\tK23333 RMND5; E3 ubiquitin-protein transferase RMND5 [EC:2.3.2.27]"
				},
				{
					"name":"100727307 Ranbp9; ran-binding protein 9\tK23334 RANBP9_10; Ran-binding protein 9\/10"
				},
				{
					"name":"100729372 Ranbp10; ran-binding protein 10\tK23334 RANBP9_10; Ran-binding protein 9\/10"
				},
				{
					"name":"100726871 Armc8; armadillo repeat-containing protein 8 isoform X1\tK23336 ARMC8; armadillo repeat-containing protein 8"
				},
				{
					"name":"100727854 Mkln1; muskelin isoform X1\tK23337 MKLN1; muskelin"
				},
				{
					"name":"100719481 Maea; macrophage erythroblast attacher isoform X2\tK18624 MAEA; macrophage erythroblast attacher"
				},
				{
					"name":"100727759 Gid4; glucose-induced degradation protein 4 homolog\tK23335 GID4; glucose-induced degradation protein 4"
				},
				{
					"name":"100734210 Gid8; glucose-induced degradation protein 8 homolog\tK23338 GID8; glucose-induced degradation protein 8"
				},
				{
					"name":"100729553 Ypel5; protein yippee-like 5\tK23339 YPEL5; protein yippee-like 5"
				},
				{
					"name":"100734086 Wdr26; WD repeat-containing protein 26 isoform X4\tK22382 WDR26; WD repeat-containing protein 26"
				}
				]
			},
			{
				"name":"ERAD complex",
				"children":[
				{
					"name":"100729655 Amfr; E3 ubiquitin-protein ligase AMFR\tK10636 AMFR; E3 ubiquitin-protein ligase AMFR [EC:2.3.2.36]"
				},
				{
					"name":"100713284 Tmub1; transmembrane and ubiquitin-like domain-containing protein 1\tK23340 TMUB; transmembrane and ubiquitin-like domain-containing protein"
				},
				{
					"name":"100729058 Tmub2; LOW QUALITY PROTEIN: transmembrane and ubiquitin-like domain-containing protein 2\tK23340 TMUB; transmembrane and ubiquitin-like domain-containing protein"
				},
				{
					"name":"100726082 Erlin1; erlin-1\tK23341 ERLIN; erlin"
				},
				{
					"name":"100734771 Erlin2; erlin-2 isoform X1\tK23341 ERLIN; erlin"
				}
				]
			},
			{
				"name":"LMBR1L-GP78-UBAC2 complex",
				"children":[
				{
					"name":"100727250 Lmbr1l; protein LMBR1L\tK25215 LMBR1L; protein LMBR1L"
				},
				{
					"name":"100729655 Amfr; E3 ubiquitin-protein ligase AMFR\tK10636 AMFR; E3 ubiquitin-protein ligase AMFR [EC:2.3.2.36]"
				},
				{
					"name":"100712776 Ubac2; ubiquitin-associated domain-containing protein 2\tK25216 UBAC2; ubiquitin-associated domain-containing protein 2"
				}
				]
			},
			{
				"name":"STUB1-CHIC2  complex",
				"children":[
				{
					"name":"100717320 Stub1; E3 ubiquitin-protein ligase CHIP isoform X1\tK09561 STUB1; STIP1 homology and U-box containing protein 1 [EC:2.3.2.27]"
				},
				{
					"name":"100725660 Chic2; cysteine-rich hydrophobic domain-containing protein 2\tK28185 CHIC2; cysteine-rich hydrophobic domain-containing protein 2"
				}
				]
			},
			{
				"name":"SLX5-SLX8 complex"
			},
			{
				"name":"Multi subunit type E3 associated proteins",
				"children":[
				{
					"name":"100734932 Cand1; cullin-associated NEDD8-dissociated protein 1\tK17263 CAND1; cullin-associated NEDD8-dissociated protein 1"
				},
				{
					"name":"100720670 Cand2; cullin-associated NEDD8-dissociated protein 2\tK24172 CAND2; cullin-associated NEDD8-dissociated protein 2"
				},
				{
					"name":"100731728 Commd1; COMM domain-containing protein 1 isoform X1\tK22557 COMMD1; COMM domain containing 1"
				},
				{
					"name":"100717124 Commd2; COMM domain-containing protein 2 isoform X1\tK22558 COMMD2; COMM domain containing 2"
				},
				{
					"name":"106024961 Commd3; COMM domain-containing protein 3 isoform X1\tK22559 COMMD3; COMM domain containing 3"
				},
				{
					"name":"100735989 Commd4; COMM domain-containing protein 4 isoform X1\tK22560 COMMD4; COMM domain containing 4"
				},
				{
					"name":"100717896 Commd5; COMM domain-containing protein 5\tK22561 COMMD5; COMM domain containing 5"
				},
				{
					"name":"100728464 Commd6; COMM domain-containing protein 6\tK22562 COMMD6; COMM domain containing 6"
				},
				{
					"name":"100732691 Commd7; COMM domain-containing protein 7 isoform X1\tK22563 COMMD7; COMM domain containing 7"
				},
				{
					"name":"100721713 Commd8; LOW QUALITY PROTEIN: COMM domain-containing protein 8\tK22564 COMMD8; COMM domain containing 8"
				},
				{
					"name":"100725006 Commd9; COMM domain-containing protein 9\tK22565 COMMD9; COMM domain containing 9"
				},
				{
					"name":"100714132 Commd10; COMM domain-containing protein 10 isoform X2\tK22566 COMMD10; COMM domain containing 10"
				},
				{
					"name":"100735327 Ccdc22; LOW QUALITY PROTEIN: coiled-coil domain-containing protein 22\tK23343 CCDC22; coiled-coil domain-containing protein 22"
				},
				{
					"name":"100719163 Ddrgk1; DDRGK domain-containing protein 1\tK23344 DDRGK1; DDRGK domain-containing protein 1"
				},
				{
					"name":"100720755 Glmn; LOW QUALITY PROTEIN: glomulin\tK23345 GLMN; glomulin"
				},
				{
					"name":"100719250 Ivns1abp; influenza virus NS1A-binding protein isoform X1\tK15046 IVNS1ABP; influenza virus NS1A-binding protein"
				},
				{
					"name":"100714793 Ubxn7; LOW QUALITY PROTEIN: UBX domain-containing protein 7\tK24350 UBXN7; UBX domain-containing protein 7"
				},
				{
					"name":"100731819 Pacrg; parkin coregulated gene protein\tK26163 PACRG; parkin coregulated gene protein"
				},
				{
					"name":"100724381 Ubap2; ubiquitin-associated protein 2 isoform X1\tK26545 UBAP2; ubiquitin-associated protein 2"
				},
				{
					"name":"100730762 Ubap2l; ubiquitin-associated protein 2-like isoform X1\tK26545 UBAP2; ubiquitin-associated protein 2"
				},
				{
					"name":"100712869 Uevld; ubiquitin-conjugating enzyme E2 variant 3 isoform X1\tK28518 UEVLD; ubiquitin-conjugating enzyme E2 variant 3"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Deubiquitinating enzyme (DUB)",
		"children":[
		{
			"name":"Ubiquitin-specific proteases (UBPs)",
			"children":[
			{
				"name":"UCH",
				"children":[
				{
					"name":"100714582 Uchl1; ubiquitin carboxyl-terminal hydrolase isozyme L1\tK05611 UCHL1; ubiquitin carboxyl-terminal hydrolase L1 [EC:3.4.19.12]"
				},
				{
					"name":"100731081 Bap1; ubiquitin carboxyl-terminal hydrolase BAP1 isoform X1\tK08588 BAP1; ubiquitin carboxyl-terminal hydrolase BAP1 [EC:3.4.19.12]"
				},
				{
					"name":"100728179 Uchl3; ubiquitin carboxyl-terminal hydrolase isozyme L3\tK05609 UCHL3; ubiquitin carboxyl-terminal hydrolase L3 [EC:3.4.19.12]"
				},
				{
					"name":"100735571 Uchl5; ubiquitin carboxyl-terminal hydrolase isozyme L5\tK05610 UCHL5; ubiquitin carboxyl-terminal hydrolase L5 [EC:3.4.19.12]"
				}
				]
			},
			{
				"name":"UBP\/USP",
				"children":[
				{
					"name":"100732328 Cyld; ubiquitin carboxyl-terminal hydrolase CYLD isoform X1\tK08601 CYLD; ubiquitin carboxyl-terminal hydrolase CYLD [EC:3.4.19.12]"
				},
				{
					"name":"100722039 Usp1; ubiquitin carboxyl-terminal hydrolase 1\tK11832 USP1; ubiquitin carboxyl-terminal hydrolase 1 [EC:3.4.19.12]"
				},
				{
					"name":"100716929 Usp2; ubiquitin carboxyl-terminal hydrolase 2 isoform X1\tK11833 USP2; ubiquitin carboxyl-terminal hydrolase 2 [EC:3.4.19.12]"
				},
				{
					"name":"100713780 Usp3; ubiquitin carboxyl-terminal hydrolase 3 isoform X1\tK11986 USP3; ubiquitin carboxyl-terminal hydrolase 3 [EC:3.4.19.12]"
				},
				{
					"name":"100726894 Usp11; ubiquitin carboxyl-terminal hydrolase 11\tK11835 USP4_11; ubiquitin carboxyl-terminal hydrolase 4\/11 [EC:3.4.19.12]"
				},
				{
					"name":"100728835 Usp4; ubiquitin carboxyl-terminal hydrolase 4 isoform X1\tK11835 USP4_11; ubiquitin carboxyl-terminal hydrolase 4\/11 [EC:3.4.19.12]"
				},
				{
					"name":"100712817 Usp13; ubiquitin carboxyl-terminal hydrolase 13\tK11836 USP5_13; ubiquitin carboxyl-terminal hydrolase 5\/13 [EC:3.4.19.12]"
				},
				{
					"name":"100724997 Usp5; ubiquitin carboxyl-terminal hydrolase 5 isoform X2\tK11836 USP5_13; ubiquitin carboxyl-terminal hydrolase 5\/13 [EC:3.4.19.12]"
				},
				{
					"name":"100730914 Usp32; ubiquitin carboxyl-terminal hydrolase 32\tK11837 USP6_32; ubiquitin carboxyl-terminal hydrolase 6\/32 [EC:3.4.19.12]"
				},
				{
					"name":"100726431 Usp7; ubiquitin carboxyl-terminal hydrolase 7 isoform X1\tK11838 USP7; ubiquitin carboxyl-terminal hydrolase 7 [EC:3.4.19.12]"
				},
				{
					"name":"100720255 Usp8; ubiquitin carboxyl-terminal hydrolase 8\tK11839 USP8; ubiquitin carboxyl-terminal hydrolase 8 [EC:3.4.19.12]"
				},
				{
					"name":"100717091 Usp9x; probable ubiquitin carboxyl-terminal hydrolase FAF-X\tK11840 USP9_24; ubiquitin carboxyl-terminal hydrolase 9\/24 [EC:3.4.19.12]"
				},
				{
					"name":"100731262 Usp24; ubiquitin carboxyl-terminal hydrolase 24\tK11840 USP9_24; ubiquitin carboxyl-terminal hydrolase 9\/24 [EC:3.4.19.12]"
				},
				{
					"name":"100716490 Usp10; ubiquitin carboxyl-terminal hydrolase 10\tK11841 USP10; ubiquitin carboxyl-terminal hydrolase 10 [EC:3.4.19.12]"
				},
				{
					"name":"100724761 Usp46; ubiquitin carboxyl-terminal hydrolase 46 isoform X1\tK11842 USP12_46; ubiquitin carboxyl-terminal hydrolase 12\/46 [EC:3.4.19.12]"
				},
				{
					"name":"100730392 Usp12; ubiquitin carboxyl-terminal hydrolase 12\tK11842 USP12_46; ubiquitin carboxyl-terminal hydrolase 12\/46 [EC:3.4.19.12]"
				},
				{
					"name":"100719247 Usp14; ubiquitin carboxyl-terminal hydrolase 14\tK11843 USP14; ubiquitin carboxyl-terminal hydrolase 14 [EC:3.4.19.12]"
				},
				{
					"name":"100734747 Usp15; ubiquitin carboxyl-terminal hydrolase 15 isoform X1\tK21343 USP15; ubiquitin carboxyl-terminal hydrolase 15 [EC:3.4.19.12]"
				},
				{
					"name":"100713634 Usp45; ubiquitin carboxyl-terminal hydrolase 45\tK11844 USP16_45; ubiquitin carboxyl-terminal hydrolase 16\/45 [EC:3.4.19.12]"
				},
				{
					"name":"100713735 Usp16; ubiquitin carboxyl-terminal hydrolase 16\tK11844 USP16_45; ubiquitin carboxyl-terminal hydrolase 16\/45 [EC:3.4.19.12]"
				},
				{
					"name":"100715648 ubiquitin carboxyl-terminal hydrolase 17-like protein 6\tK11845 USP17; ubiquitin carboxyl-terminal hydrolase 17 [EC:3.4.19.12]"
				},
				{
					"name":"100729301 Usp18; ubl carboxyl-terminal hydrolase 18\tK11846 USP18_41; ubiquitin carboxyl-terminal hydrolase 18\/41 [EC:3.4.19.12]"
				},
				{
					"name":"100731773 Usp19; ubiquitin carboxyl-terminal hydrolase 19 isoform X5\tK11847 USP19; ubiquitin carboxyl-terminal hydrolase 19 [EC:3.4.19.12]"
				},
				{
					"name":"100714166 Usp33; ubiquitin carboxyl-terminal hydrolase 33\tK11848 USP20_33; ubiquitin carboxyl-terminal hydrolase 20\/33 [EC:3.4.19.12]"
				},
				{
					"name":"100729086 Usp20; ubiquitin carboxyl-terminal hydrolase 20\tK11848 USP20_33; ubiquitin carboxyl-terminal hydrolase 20\/33 [EC:3.4.19.12]"
				},
				{
					"name":"100735355 Usp21; ubiquitin carboxyl-terminal hydrolase 21\tK21634 USP21; ubiquitin carboxyl-terminal hydrolase 21 [EC:3.4.19.12]"
				},
				{
					"name":"100721848 Usp27x; ubiquitin carboxyl-terminal hydrolase 27\tK11366 USP22_27_51; ubiquitin carboxyl-terminal hydrolase 22\/27\/51 [EC:3.4.19.12]"
				},
				{
					"name":"100729060 Usp22; ubiquitin carboxyl-terminal hydrolase 22\tK11366 USP22_27_51; ubiquitin carboxyl-terminal hydrolase 22\/27\/51 [EC:3.4.19.12]"
				},
				{
					"name":"100730631 Usp25; ubiquitin carboxyl-terminal hydrolase 25 isoform X1\tK11849 USP25; ubiquitin carboxyl-terminal hydrolase 25 [EC:3.4.19.12]"
				},
				{
					"name":"100725433 Usp26; ubiquitin carboxyl-terminal hydrolase 26\tK11850 USP26_29_37; ubiquitin carboxyl-terminal hydrolase 26\/29\/37 [EC:3.4.19.12]"
				},
				{
					"name":"100726363 Usp37; ubiquitin carboxyl-terminal hydrolase 37\tK11850 USP26_29_37; ubiquitin carboxyl-terminal hydrolase 26\/29\/37 [EC:3.4.19.12]"
				},
				{
					"name":"100713115 Usp28; ubiquitin carboxyl-terminal hydrolase 28 isoform X7\tK21122 USP28; ubiquitin carboxyl-terminal hydrolase 28 [EC:3.4.19.12]"
				},
				{
					"name":"100733919 Usp30; ubiquitin carboxyl-terminal hydrolase 30 isoform X1\tK11851 USP30; ubiquitin carboxyl-terminal hydrolase 30 [EC:3.4.19.12]"
				},
				{
					"name":"100715744 Usp31; ubiquitin carboxyl-terminal hydrolase 31\tK11852 USP31; ubiquitin carboxyl-terminal hydrolase 31 [EC:3.4.19.12]"
				},
				{
					"name":"100732825 Usp34; ubiquitin carboxyl-terminal hydrolase 34\tK11853 USP34; ubiquitin carboxyl-terminal hydrolase 34 [EC:3.4.19.12]"
				},
				{
					"name":"100730769 Usp38; ubiquitin carboxyl-terminal hydrolase 38\tK11854 USP35_38; ubiquitin carboxyl-terminal hydrolase 35\/38 [EC:3.4.19.12]"
				},
				{
					"name":"100735366 Usp35; LOW QUALITY PROTEIN: ubiquitin carboxyl-terminal hydrolase 35\tK11854 USP35_38; ubiquitin carboxyl-terminal hydrolase 35\/38 [EC:3.4.19.12]"
				},
				{
					"name":"100717369 ubiquitin carboxyl-terminal hydrolase 42 isoform X1\tK11855 USP36_42; ubiquitin carboxyl-terminal hydrolase 36\/42 [EC:3.4.19.12]"
				},
				{
					"name":"100719875 LOW QUALITY PROTEIN: ubiquitin carboxyl-terminal hydrolase 42-like\tK11855 USP36_42; ubiquitin carboxyl-terminal hydrolase 36\/42 [EC:3.4.19.12]"
				},
				{
					"name":"100720970 ubiquitin carboxyl-terminal hydrolase 42-like\tK11855 USP36_42; ubiquitin carboxyl-terminal hydrolase 36\/42 [EC:3.4.19.12]"
				},
				{
					"name":"100723179 LOW QUALITY PROTEIN: ubiquitin carboxyl-terminal hydrolase 42-like\tK11855 USP36_42; ubiquitin carboxyl-terminal hydrolase 36\/42 [EC:3.4.19.12]"
				},
				{
					"name":"100729015 ubiquitin carboxyl-terminal hydrolase 42-like\tK11855 USP36_42; ubiquitin carboxyl-terminal hydrolase 36\/42 [EC:3.4.19.12]"
				},
				{
					"name":"100731912 Usp36; ubiquitin carboxyl-terminal hydrolase 36 isoform X3\tK11855 USP36_42; ubiquitin carboxyl-terminal hydrolase 36\/42 [EC:3.4.19.12]"
				},
				{
					"name":"100735536 ubiquitin carboxyl-terminal hydrolase 42-like\tK11855 USP36_42; ubiquitin carboxyl-terminal hydrolase 36\/42 [EC:3.4.19.12]"
				},
				{
					"name":"101788978 ubiquitin carboxyl-terminal hydrolase 42-like\tK11855 USP36_42; ubiquitin carboxyl-terminal hydrolase 36\/42 [EC:3.4.19.12]"
				},
				{
					"name":"100721912 Usp40; ubiquitin carboxyl-terminal hydrolase 40 isoform X1\tK11869 USP40; ubiquitin carboxyl-terminal hydrolase 40 [EC:3.4.19.12]"
				},
				{
					"name":"100735629 Usp43; ubiquitin carboxyl-terminal hydrolase 43 isoform X3\tK11856 USP43; ubiquitin carboxyl-terminal hydrolase 43 [EC:3.4.19.12]"
				},
				{
					"name":"100715999 Usp49; ubiquitin carboxyl-terminal hydrolase 49 isoform X1\tK11834 USP44_49; ubiquitin carboxyl-terminal hydrolase 44\/49 [EC:3.4.19.12]"
				},
				{
					"name":"100724229 Usp44; LOW QUALITY PROTEIN: ubiquitin carboxyl-terminal hydrolase 44\tK11834 USP44_49; ubiquitin carboxyl-terminal hydrolase 44\/49 [EC:3.4.19.12]"
				},
				{
					"name":"100728785 Usp47; ubiquitin carboxyl-terminal hydrolase 47 isoform X2\tK11857 USP47; ubiquitin carboxyl-terminal hydrolase 47 [EC:3.4.19.12]"
				},
				{
					"name":"100725391 Usp48; ubiquitin carboxyl-terminal hydrolase 48\tK11858 USP48; ubiquitin carboxyl-terminal hydrolase 48 [EC:3.4.19.12]"
				},
				{
					"name":"100716271 Usp50; inactive ubiquitin carboxyl-terminal hydrolase 50\tK28833 USP50; ubiquitin carboxyl-terminal hydrolase 50 [EC:3.4.19.12]"
				},
				{
					"name":"100719435 Usp54; inactive ubiquitin carboxyl-terminal hydrolase 54 isoform X3\tK27920 USP54; ubiquitin carboxyl-terminal hydrolase 54 [EC:3.4.19.12]"
				}
				]
			},
			{
				"name":"OTU",
				"children":[
				{
					"name":"100714472 Otub1; ubiquitin thioesterase OTUB1\tK09602 OTUB1; ubiquitin thioesterase protein OTUB1 [EC:3.4.19.12]"
				},
				{
					"name":"100735239 Otub2; ubiquitin thioesterase OTUB2\tK09603 OTUB2; ubiquitin thioesterase protein OTUB2 [EC:3.4.19.12]"
				},
				{
					"name":"100722449 Otud3; OTU domain-containing protein 3\tK13717 OTUD3; OTU domain-containing protein 3 [EC:3.4.19.12]"
				},
				{
					"name":"100732793 Otud5; LOW QUALITY PROTEIN: OTU domain-containing protein 5\tK12655 OTUD5; OTU domain-containing protein 5 [EC:3.4.19.12]"
				},
				{
					"name":"100713163 Otud6b; OTU domain-containing protein 6B\tK18342 OTUD6; OTU domain-containing protein 6 [EC:3.4.19.12]"
				},
				{
					"name":"100717004 Otud6a; OTU domain-containing protein 6A\tK18342 OTUD6; OTU domain-containing protein 6 [EC:3.4.19.12]"
				},
				{
					"name":"100719181 Otud7b; OTU domain-containing protein 7B\tK11860 OTUD7A_B; OTU domain-containing protein 7 [EC:3.4.19.12]"
				},
				{
					"name":"100720085 Otud7a; OTU domain-containing protein 7A\tK11860 OTUD7A_B; OTU domain-containing protein 7 [EC:3.4.19.12]"
				},
				{
					"name":"100734234 Otulin; ubiquitin thioesterase otulin\tK18343 OTULIN; ubiquitin thioesterase otulin [EC:3.4.19.12]"
				},
				{
					"name":"100720503 Tnfaip3; tumor necrosis factor alpha-induced protein 3\tK11859 TNFAIP3; tumor necrosis factor, alpha-induced protein 3 [EC:3.4.19.12]"
				},
				{
					"name":"100717717 Vcpip1; deubiquitinating protein VCIP135\tK11861 VCPIP1; deubiquitinating protein VCIP135 [EC:3.4.19.12]"
				},
				{
					"name":"100734408 Zranb1; ubiquitin thioesterase ZRANB1 isoform X1\tK11862 ZRANB1; ubiquitin thioesterase ZRANB1 [EC:3.4.19.12]"
				}
				]
			},
			{
				"name":"MJD",
				"children":[
				{
					"name":"100713724 LOW QUALITY PROTEIN: ataxin-3-like\tK11863 ATXN3; ataxin-3 [EC:3.4.22.-]"
				},
				{
					"name":"100719182 Atxn3; ataxin-3\tK11863 ATXN3; ataxin-3 [EC:3.4.22.-]"
				},
				{
					"name":"100718654 Josd2; josephin-2\tK15235 JOSD; josephin [EC:3.4.19.12]"
				},
				{
					"name":"100729641 Josd1; josephin-1\tK15235 JOSD; josephin [EC:3.4.19.12]"
				}
				]
			},
			{
				"name":"MINDY",
				"children":[
				{
					"name":"100722687 ubiquitin carboxyl-terminal hydrolase MINDY-2\tK01309 MINDY1_2; ubiquitin carboxyl-terminal hydrolase MINDY-1\/2 [EC:3.4.19.12]"
				},
				{
					"name":"100725698 Mindy1; ubiquitin carboxyl-terminal hydrolase MINDY-1 isoform X1\tK01309 MINDY1_2; ubiquitin carboxyl-terminal hydrolase MINDY-1\/2 [EC:3.4.19.12]"
				},
				{
					"name":"100715588 Mindy4; probable ubiquitin carboxyl-terminal hydrolase MINDY-4 isoform X2\tK22647 MINDY3_4; ubiquitin carboxyl-terminal hydrolase MINDY-3\/4 [EC:3.4.19.12]"
				},
				{
					"name":"100721663 Mindy3; ubiquitin carboxyl-terminal hydrolase MINDY-3 isoform X1\tK22647 MINDY3_4; ubiquitin carboxyl-terminal hydrolase MINDY-3\/4 [EC:3.4.19.12]"
				},
				{
					"name":"111753444 Mindy4b; inactive ubiquitin carboxyl-terminal hydrolase MINDY-4B\tK22647 MINDY3_4; ubiquitin carboxyl-terminal hydrolase MINDY-3\/4 [EC:3.4.19.12]"
				}
				]
			},
			{
				"name":"JAMM",
				"children":[
				{
					"name":"100719736 Brcc3; lys-63-specific deubiquitinase BRCC36 isoform X1\tK11864 BRCC3; BRCA1\/BRCA2-containing complex subunit 3 [EC:3.4.19.-]"
				},
				{
					"name":"100729049 Mysm1; histone H2A deubiquitinase MYSM1 isoform X3\tK11865 MYSM1; histone H2A deubiquitinase [EC:3.4.19.-]"
				},
				{
					"name":"100736147 Mpnd; LOW QUALITY PROTEIN: MPN domain-containing protein\tK24173 MPND; MPN domain-containing protein"
				},
				{
					"name":"100721655 Psmd14; 26S proteasome non-ATPase regulatory subunit 14\tK03030 PSMD14; 26S proteasome regulatory subunit N11"
				},
				{
					"name":"100716723 Stambp; STAM-binding protein\tK11866 STAMBP; STAM-binding protein [EC:3.4.19.12]"
				},
				{
					"name":"100720263 Stambpl1; AMSH-like protease\tK11867 STAMBPL1; AMSH-like protease [EC:3.4.19.12]"
				}
				]
			},
			{
				"name":"PPPDE",
				"children":[
				{
					"name":"100724590 Desi2; desumoylating isopeptidase 2\tK22763 DESI2; deubiquitinase DESI2 [EC:3.4.19.12]"
				}
				]
			},
			{
				"name":"ZUFSP",
				"children":[
				{
					"name":"100717992 Zufsp; zinc finger with UFM1-specific peptidase domain protein isoform X2\tK24134 ZUP1; zinc finger-containing ubiquitin peptidase 1 [EC:3.4.19.12]"
				}
				]
			},
			{
				"name":"BRISC complex",
				"children":[
				{
					"name":"100734687 Abraxas2; BRISC complex subunit Abraxas 2\tK20799 FAM175B; BRISC complex subunit Abro1"
				},
				{
					"name":"100732454 Babam1; BRISC and BRCA1-A complex member 1 isoform X2\tK20776 BABAM; BRISC and BRCA1-A complex member 1"
				},
				{
					"name":"100719736 Brcc3; lys-63-specific deubiquitinase BRCC36 isoform X1\tK11864 BRCC3; BRCA1\/BRCA2-containing complex subunit 3 [EC:3.4.19.-]"
				},
				{
					"name":"100725666 Babam2; BRISC and BRCA1-A complex member 2\tK12173 BRE; BRCA1-A complex subunit BRE"
				}
				]
			}
			]
		},
		{
			"name":"UBL-specific proteases (ULPs)",
			"children":[
			{
				"name":"100723394 Senp1; sentrin-specific protease 1 isoform X2\tK08592 SENP1; sentrin-specific protease 1 [EC:3.4.22.68]"
			},
			{
				"name":"100727432 Senp2; sentrin-specific protease 2 isoform X1\tK03345 SENP2; sentrin-specific protease 2 (axin associating molecule) [EC:3.4.22.68]"
			},
			{
				"name":"100712993 Senp3; sentrin-specific protease 3\tK08593 SENP3; sentrin-specific protease 3 [EC:3.4.22.68]"
			},
			{
				"name":"100712863 Senp5; sentrin-specific protease 5 isoform X1\tK08594 SENP5; sentrin-specific protease 5 [EC:3.4.22.68]"
			},
			{
				"name":"100715646 Senp6; sentrin-specific protease 6 isoform X1\tK08595 SENP6; sentrin-specific protease 6 [EC:3.4.22.68]"
			},
			{
				"name":"100725297 Senp7; sentrin-specific protease 7\tK08596 SENP7; sentrin-specific protease 7 [EC:3.4.22.68]"
			},
			{
				"name":"100715270 Senp8; sentrin-specific protease 8\tK08597 SENP8; sentrin-specific protease 8 [EC:3.4.22.68]"
			},
			{
				"name":"100728179 Uchl3; ubiquitin carboxyl-terminal hydrolase isozyme L3\tK05609 UCHL3; ubiquitin carboxyl-terminal hydrolase L3 [EC:3.4.19.12]"
			},
			{
				"name":"100712832 Desi1; desumoylating isopeptidase 1 isoform X1\tK22762 DESI1; desumoylating isopeptidase 1 [EC:3.4.-.-]"
			},
			{
				"name":"100722930 Uspl1; SUMO-specific isopeptidase USPL1\tK23008 USPL1; SUMO-specific isopeptidase USPL1 [EC:3.4.22.-]"
			},
			{
				"name":"COP9 signalosome (CSN) complex",
				"children":[
				{
					"name":"100713341 Gps1; COP9 signalosome complex subunit 1 isoform X4\tK12175 GPS1; COP9 signalosome complex subunit 1"
				},
				{
					"name":"100714584 Cops2; COP9 signalosome complex subunit 2 isoform X2\tK12176 COPS2; COP9 signalosome complex subunit 2"
				},
				{
					"name":"100730261 Cops3; COP9 signalosome complex subunit 3\tK12177 COPS3; COP9 signalosome complex subunit 3"
				},
				{
					"name":"100722440 Cops4; COP9 signalosome complex subunit 4\tK12178 COPS4; COP9 signalosome complex subunit 4"
				},
				{
					"name":"100716886 Cops5; COP9 signalosome complex subunit 5 isoform X1\tK09613 COPS5; COP9 signalosome complex subunit 5 [EC:3.4.-.-]"
				},
				{
					"name":"100719508 Cops6; COP9 signalosome complex subunit 6\tK12179 COPS6; COP9 signalosome complex subunit 6"
				},
				{
					"name":"100725494 Cops7b; COP9 signalosome complex subunit 7b\tK12180 COPS7; COP9 signalosome complex subunit 7"
				},
				{
					"name":"100726443 Cops7a; COP9 signalosome complex subunit 7a isoform X3\tK12180 COPS7; COP9 signalosome complex subunit 7"
				},
				{
					"name":"100729283 Cops8; COP9 signalosome complex subunit 8\tK12181 COPS8; COP9 signalosome complex subunit 8"
				},
				{
					"name":"100726221 Cops9; COP9 signalosome complex subunit 9\tK28062 COPS9; COP9 signalosome complex subunit 9"
				}
				]
			}
			]
		}
		]
	}
	]
}