{
	"name":"crid04121",
	"children":[
	{
		"name":"Ubiquitins and ubiquitin-like proteins",
		"children":[
		{
			"name":"Ubiquitins",
			"children":[
			{
				"name":"134518523 UBC; (RefSeq) polyubiquitin-C\tK08770 UBB_C; ubiquitin B\/C"
			},
			{
				"name":"134522924 UBB; (RefSeq) polyubiquitin-B\tK08770 UBB_C; ubiquitin B\/C"
			},
			{
				"name":"134526354 UBA52; (RefSeq) ubiquitin-ribosomal protein eL40 fusion protein\tK02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e"
			},
			{
				"name":"134513941 RPS27A; (RefSeq) ubiquitin-ribosomal protein eS31 fusion protein\tK02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae"
			}
			]
		},
		{
			"name":"Ubiquitin-like proteins (UBLs)",
			"children":[
			{
				"name":"134517726 small ubiquitin-related modifier 3\tK12160 SUMO; small ubiquitin-related modifier"
			},
			{
				"name":"134518339 SUMO1; (RefSeq) small ubiquitin-related modifier 1\tK12160 SUMO; small ubiquitin-related modifier"
			},
			{
				"name":"134523357 SUMO2; (RefSeq) small ubiquitin-related modifier 2 isoform X1\tK12160 SUMO; small ubiquitin-related modifier"
			},
			{
				"name":"134515712 GABARAPL2; (RefSeq) gamma-aminobutyric acid receptor-associated protein-like 2\tK08341 GABARAP; GABA(A) receptor-associated protein"
			},
			{
				"name":"134525459 GABARAPL1; (RefSeq) gamma-aminobutyric acid receptor-associated protein-like 1\tK08341 GABARAP; GABA(A) receptor-associated protein"
			},
			{
				"name":"134508474 ATG12; (RefSeq) ubiquitin-like protein ATG12\tK08336 ATG12; ubiquitin-like protein ATG12"
			},
			{
				"name":"134523863 URM1; (RefSeq) ubiquitin-related modifier 1\tK12161 URM1; ubiquitin related modifier 1"
			},
			{
				"name":"134514878 UFM1; (RefSeq) ubiquitin-fold modifier 1\tK12162 UFM1; ubiquitin-fold modifier 1"
			},
			{
				"name":"134514361 UBL3; (RefSeq) ubiquitin-like protein 3\tK28515 UBL3; membrane-anchored ubiquitin-fold protein"
			},
			{
				"name":"134517682 ZFAND4; (RefSeq) AN1-type zinc finger protein 4 isoform X1\tK12163 ZFAND4; AN1-type zinc finger protein 4"
			}
			]
		}
		]
	},
	{
		"name":"Ubiquitin-activating enzymes (E1)",
		"children":[
		{
			"name":"Ubiquitin activating enzyme",
			"children":[
			{
				"name":"134508046 UBA1; (RefSeq) ubiquitin-like modifier-activating enzyme 1\tK03178 UBE1; ubiquitin-activating enzyme E1 [EC:6.2.1.45]"
			},
			{
				"name":"134521698 UBA7; (RefSeq) ubiquitin-like modifier-activating enzyme 7 isoform X1\tK03178 UBE1; ubiquitin-activating enzyme E1 [EC:6.2.1.45]"
			}
			]
		},
		{
			"name":"UBL-activating enzymes",
			"children":[
			{
				"name":"134507684 SAE1; (RefSeq) SUMO-activating enzyme subunit 1\tK10684 UBLE1A; ubiquitin-like 1-activating enzyme E1 A [EC:6.2.1.45]"
			},
			{
				"name":"134515529 UBA2; (RefSeq) SUMO-activating enzyme subunit 2\tK10685 UBLE1B; ubiquitin-like 1-activating enzyme E1 B [EC:6.2.1.45]"
			},
			{
				"name":"134521345 UBA3; (RefSeq) NEDD8-activating enzyme E1 catalytic subunit isoform X1\tK10686 UBA3; NEDD8-activating enzyme E1 [EC:6.2.1.64]"
			},
			{
				"name":"134515537 NAE1; (RefSeq) NEDD8-activating enzyme E1 regulatory subunit isoform X1\tK04532 NAE1; NEDD8-activating enzyme E1 regulatory subunit"
			},
			{
				"name":"134522614 MOCS3; (RefSeq) adenylyltransferase and sulfurtransferase MOCS3\tK11996 MOCS3; adenylyltransferase and sulfurtransferase [EC:2.7.7.80 2.8.1.11]"
			},
			{
				"name":"134511422 UBA5; (RefSeq) ubiquitin-like modifier-activating enzyme 5\tK12164 UBA5; ubiquitin-like modifier-activating enzyme 5"
			},
			{
				"name":"134515981 UBA6; (RefSeq) ubiquitin-like modifier-activating enzyme 6\tK10699 UBE1L2; ubiquitin-activating enzyme E1-like protein 2 [EC:6.2.1.45]"
			},
			{
				"name":"134521504 ATG7; (RefSeq) ubiquitin-like modifier-activating enzyme ATG7\tK08337 ATG7; ubiquitin-like modifier-activating enzyme ATG7"
			}
			]
		}
		]
	},
	{
		"name":"Ubiquitin-conjugating enzymes (E2)",
		"children":[
		{
			"name":"Ubiquitin-conjugating enzymes",
			"children":[
			{
				"name":"134521211 UBE2A; (RefSeq) ubiquitin-conjugating enzyme E2 A\tK10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]"
			},
			{
				"name":"134521989 UBE2B; (RefSeq) ubiquitin-conjugating enzyme E2 B isoform X1\tK10574 UBE2B; ubiquitin-conjugating enzyme E2 B [EC:2.3.2.23]"
			},
			{
				"name":"134522399 UBE2C; (RefSeq) ubiquitin-conjugating enzyme E2 C\tK06688 UBE2C; ubiquitin-conjugating enzyme E2 C [EC:2.3.2.23]"
			},
			{
				"name":"134517696 UBE2D1; (RefSeq) ubiquitin-conjugating enzyme E2 D1 isoform X1\tK06689 UBE2D; ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]"
			},
			{
				"name":"134519144 LOW QUALITY PROTEIN: ubiquitin-conjugating enzyme E2 D2-like\tK06689 UBE2D; ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]"
			},
			{
				"name":"134522087 UBE2D2; (RefSeq) ubiquitin-conjugating enzyme E2 D2 isoform X1\tK06689 UBE2D; ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]"
			},
			{
				"name":"134511359 ubiquitin-conjugating enzyme E2 E2\tK20217 UBE2E; ubiquitin-conjugating enzyme E2 E [EC:2.3.2.23]"
			},
			{
				"name":"134511360 ubiquitin-conjugating enzyme E2 E1 isoform X1\tK20217 UBE2E; ubiquitin-conjugating enzyme E2 E [EC:2.3.2.23]"
			},
			{
				"name":"134518658 UBE2E3; (RefSeq) ubiquitin-conjugating enzyme E2 E3 isoform X1\tK20217 UBE2E; ubiquitin-conjugating enzyme E2 E [EC:2.3.2.23]"
			},
			{
				"name":"134518371 UBE2G1; (RefSeq) ubiquitin-conjugating enzyme E2 G1\tK10575 UBE2G1; ubiquitin-conjugating enzyme E2 G1 [EC:2.3.2.23]"
			},
			{
				"name":"134517605 UBE2G2; (RefSeq) ubiquitin-conjugating enzyme E2 G2\tK04555 UBE2G2; ubiquitin-conjugating enzyme E2 G2 [EC:2.3.2.23]"
			},
			{
				"name":"134510442 UBE2H; (RefSeq) ubiquitin-conjugating enzyme E2 H isoform X1\tK10576 UBE2H; ubiquitin-conjugating enzyme E2 H [EC:2.3.2.23]"
			},
			{
				"name":"134513384 UBE2J1; (RefSeq) ubiquitin-conjugating enzyme E2 J1\tK10578 UBE2J1; ubiquitin-conjugating enzyme E2 J1 [EC:2.3.2.23]"
			},
			{
				"name":"134524119 UBE2J2; (RefSeq) ubiquitin-conjugating enzyme E2 J2 isoform X1\tK04554 UBE2J2; ubiquitin-conjugating enzyme E2 J2 [EC:2.3.2.23]"
			},
			{
				"name":"134515907 UBE2K; (RefSeq) ubiquitin-conjugating enzyme E2 K isoform X1\tK04649 UBE2K; ubiquitin-conjugating enzyme (huntingtin interacting protein 2) [EC:2.3.2.23]"
			},
			{
				"name":"134515485 UBE2L6; (RefSeq) ubiquitin\/ISG15-conjugating enzyme E2 L6 isoform X1\tK04552 UBE2L3; ubiquitin-conjugating enzyme E2 L3 [EC:2.3.2.23]"
			},
			{
				"name":"134522894 UBE2L3; (RefSeq) ubiquitin-conjugating enzyme E2 L3\tK04552 UBE2L3; ubiquitin-conjugating enzyme E2 L3 [EC:2.3.2.23]"
			},
			{
				"name":"134510033 UBE2N; (RefSeq) ubiquitin-conjugating enzyme E2 N\tK10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]"
			},
			{
				"name":"134523246 UBE2O; (RefSeq) (E3-independent) E2 ubiquitin-conjugating enzyme isoform X1\tK10581 UBE2O; ubiquitin-conjugating enzyme E2 O [EC:2.3.2.24]"
			},
			{
				"name":"134511752 UBE2QL1; (RefSeq) ubiquitin-conjugating enzyme E2Q-like protein 1\tK10582 UBE2Q; ubiquitin-conjugating enzyme E2 Q [EC:2.3.2.23]"
			},
			{
				"name":"134521188 UBE2Q2; (RefSeq) ubiquitin-conjugating enzyme E2 Q2\tK10582 UBE2Q; ubiquitin-conjugating enzyme E2 Q [EC:2.3.2.23]"
			},
			{
				"name":"134525910 UBE2Q1; (RefSeq) ubiquitin-conjugating enzyme E2 Q1\tK10582 UBE2Q; ubiquitin-conjugating enzyme E2 Q [EC:2.3.2.23]"
			},
			{
				"name":"134508501 UBE2R2; (RefSeq) ubiquitin-conjugating enzyme E2 R2\tK02207 UBE2R; ubiquitin-conjugating enzyme E2 R [EC:2.3.2.23]"
			},
			{
				"name":"134526434 CDC34; (RefSeq) ubiquitin-conjugating enzyme E2 R1\tK02207 UBE2R; ubiquitin-conjugating enzyme E2 R [EC:2.3.2.23]"
			},
			{
				"name":"134525705 UBE2T; (RefSeq) ubiquitin-conjugating enzyme E2 T\tK13960 UBE2T; ubiquitin-conjugating enzyme E2 T [EC:2.3.2.23]"
			},
			{
				"name":"134512055 UBE2W; (RefSeq) ubiquitin-conjugating enzyme E2 W isoform X1\tK10688 UBE2W; ubiquitin-conjugating enzyme E2 W [EC:2.3.2.23 2.3.2.25]"
			},
			{
				"name":"134524466 UBE2Z; (RefSeq) ubiquitin-conjugating enzyme E2 Z\tK10585 UBE2Z; ubiquitin-conjugating enzyme E2 Z [EC:2.3.2.23]"
			},
			{
				"name":"134512918 BIRC6; (RefSeq) baculoviral IAP repeat-containing protein 6 isoform X1\tK10586 BIRC6; baculoviral IAP repeat-containing protein 6 (apollon) [EC:2.3.2.23]"
			}
			]
		},
		{
			"name":"UBL-conjugating enzymes",
			"children":[
			{
				"name":"134520192 UBE2I; (RefSeq) SUMO-conjugating enzyme UBC9\tK10577 UBE2I; ubiquitin-conjugating enzyme E2 I"
			},
			{
				"name":"134518139 UBE2F; (RefSeq) NEDD8-conjugating enzyme UBE2F isoform X1\tK10687 UBE2F; ubiquitin-conjugating enzyme E2 F [EC:2.3.2.34]"
			},
			{
				"name":"134507745 UBE2M; (RefSeq) LOW QUALITY PROTEIN: NEDD8-conjugating enzyme Ubc12\tK10579 UBE2M; ubiquitin-conjugating enzyme E2 M [EC:2.3.2.34]"
			},
			{
				"name":"134522798 ATG3; (RefSeq) ubiquitin-like-conjugating enzyme ATG3\tK08343 ATG3; ubiquitin-like-conjugating enzyme ATG3"
			},
			{
				"name":"134508481 ATG10; (RefSeq) ubiquitin-like-conjugating enzyme ATG10 isoform X1\tK17888 ATG10L; ubiquitin-like-conjugating enzyme ATG10"
			},
			{
				"name":"134525949 UFC1; (RefSeq) ubiquitin-fold modifier-conjugating enzyme 1\tK12165 UFC1; ufm1-conjugating enzyme 1"
			}
			]
		}
		]
	},
	{
		"name":"Ubiquitin ligases (E3)",
		"children":[
		{
			"name":"HECT type E3",
			"children":[
			{
				"name":"134517918 UBE3A; (RefSeq) ubiquitin-protein ligase E3A isoform X1\tK10587 UBE3A; ubiquitin-protein ligase E3 A [EC:2.3.2.26]"
			},
			{
				"name":"134522794 UBE3B; (RefSeq) ubiquitin-protein ligase E3B isoform X1\tK10588 UBE3B; ubiquitin-protein ligase E3 B [EC:2.3.2.26]"
			},
			{
				"name":"134511063 UBE3C; (RefSeq) ubiquitin-protein ligase E3C\tK10589 UBE3C; ubiquitin-protein ligase E3 C [EC:2.3.2.26]"
			},
			{
				"name":"134513425 UBE3D; (RefSeq) E3 ubiquitin-protein ligase E3D isoform X1\tK20803 UBE3D; ubiquitin-protein ligase E3 D [EC:2.3.2.26]"
			},
			{
				"name":"134519375 SMURF1; (RefSeq) E3 ubiquitin-protein ligase SMURF1 isoform X1\tK04678 SMURF; E3 ubiquitin ligase SMURF1\/2 [EC:2.3.2.26]"
			},
			{
				"name":"134523164 SMURF2; (RefSeq) E3 ubiquitin-protein ligase SMURF2 isoform X1\tK04678 SMURF; E3 ubiquitin ligase SMURF1\/2 [EC:2.3.2.26]"
			},
			{
				"name":"134522341 ITCH; (RefSeq) E3 ubiquitin-protein ligase Itchy homolog\tK05632 ITCH; E3 ubiquitin-protein ligase Itchy [EC:2.3.2.26]"
			},
			{
				"name":"134512095 WWP1; (RefSeq) NEDD4-like E3 ubiquitin-protein ligase WWP1 isoform X1\tK05633 WWP1; NEDD4-like E3 ubiquitin-protein ligase WWP1 [EC:2.3.2.26]"
			},
			{
				"name":"134515688 WWP2; (RefSeq) NEDD4-like E3 ubiquitin-protein ligase WWP2 isoform X1\tK05630 WWP2; NEDD4-like E3 ubiquitin-protein ligase WWP2 [EC:2.3.2.26]"
			},
			{
				"name":"134517080 TRIP12; (RefSeq) E3 ubiquitin-protein ligase TRIP12 isoform X1\tK10590 TRIP12; E3 ubiquitin-protein ligase TRIP12 [EC:2.3.2.26]"
			},
			{
				"name":"134520672 NEDD4; (RefSeq) E3 ubiquitin-protein ligase NEDD4 isoform X1\tK10591 NEDD4; E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26]"
			},
			{
				"name":"134508671 NEDD4L; (RefSeq) E3 ubiquitin-protein ligase NEDD4-like isoform X1\tK13305 NEDD4L; E3 ubiquitin-protein ligase NEDD4-like [EC:2.3.2.26]"
			},
			{
				"name":"134514820 AREL1; (RefSeq) apoptosis-resistant E3 ubiquitin protein ligase 1 isoform X1\tK22370 AREL1; apoptosis-resistant E3 ubiquitin protein ligase 1 [EC:2.3.2.26]"
			},
			{
				"name":"134512174 UBR5; (RefSeq) E3 ubiquitin-protein ligase UBR5 isoform X1\tK10593 EDD1; E3 ubiquitin-protein ligase EDD1 [EC:2.3.2.26]"
			},
			{
				"name":"134514789 G2E3; (RefSeq) G2\/M phase-specific E3 ubiquitin-protein ligase\tK22371 G2H3; G2\/M phase-specific E3 ubiquitin-protein ligase [EC:2.3.2.26]"
			},
			{
				"name":"134520447 HERC1; (RefSeq) probable E3 ubiquitin-protein ligase HERC1 isoform X1\tK10594 HERC1; E3 ubiquitin-protein ligase HERC1 [EC:2.3.2.26]"
			},
			{
				"name":"134518039 HERC2; (RefSeq) E3 ubiquitin-protein ligase HERC2 isoform X1\tK10595 HERC2; E3 ubiquitin-protein ligase HERC2 [EC:2.3.2.26]"
			},
			{
				"name":"134516707 HERC3; (RefSeq) probable E3 ubiquitin-protein ligase HERC3\tK10614 HERC3; E3 ubiquitin-protein ligase HERC3 [EC:2.3.2.26]"
			},
			{
				"name":"134516878 HERC4; (RefSeq) probable E3 ubiquitin-protein ligase HERC4 isoform X1\tK10615 HERC4; E3 ubiquitin-protein ligase HERC4 [EC:2.3.2.26]"
			},
			{
				"name":"134513347 HACE1; (RefSeq) E3 ubiquitin-protein ligase HACE1 isoform X1\tK12166 HACE1; E3 ubiquitin-protein ligase HACE1 [EC:2.3.2.26]"
			},
			{
				"name":"134511527 HECW1; (RefSeq) E3 ubiquitin-protein ligase HECW1 isoform X1\tK12167 HECW1; E3 ubiquitin-protein ligase HECW1 [EC:2.3.2.26]"
			},
			{
				"name":"134518242 HECW2; (RefSeq) E3 ubiquitin-protein ligase HECW2 isoform X1\tK12168 HECW2; E3 ubiquitin-protein ligase HECW2 [EC:2.3.2.26]"
			},
			{
				"name":"134514192 HECTD1; (RefSeq) E3 ubiquitin-protein ligase HECTD1 isoform X1\tK12231 HECTD1; E3 ubiquitin-protein ligase HECTD1 [EC:2.3.2.26]"
			},
			{
				"name":"134517505 HECTD2; (RefSeq) probable E3 ubiquitin-protein ligase HECTD2 isoform X1\tK12232 HECTD2; E3 ubiquitin-protein ligase HECTD2 [EC:2.3.2.26]"
			},
			{
				"name":"134519554 HECTD3; (RefSeq) E3 ubiquitin-protein ligase HECTD3\tK12233 HECTD3; E3 ubiquitin-protein ligase HECTD3 [EC:2.3.2.26]"
			},
			{
				"name":"134520006 E3 ubiquitin-protein ligase HECTD3-like isoform X1\tK12233 HECTD3; E3 ubiquitin-protein ligase HECTD3 [EC:2.3.2.26]"
			},
			{
				"name":"134522807 HECTD4; (RefSeq) probable E3 ubiquitin-protein ligase HECTD4 isoform X1\tK17849 HECTD4; E3 ubiquitin-protein ligase HECTD4 [EC:2.3.2.26]"
			},
			{
				"name":"HECT type E3 associated proteins",
				"children":[
				{
					"name":"134516155 NDFIP2; (RefSeq) NEDD4 family-interacting protein 2 isoform X1\tK25839 NDFIP; NEDD4 family-interacting protein"
				},
				{
					"name":"134522040 NDFIP1; (RefSeq) NEDD4 family-interacting protein 1 isoform X1\tK25839 NDFIP; NEDD4 family-interacting protein"
				},
				{
					"name":"134522165 N4BP3; (RefSeq) NEDD4-binding protein 3 isoform X1\tK26473 N4BP3; NEDD4-binding protein 3"
				},
				{
					"name":"134519254 HAPSTR1; (RefSeq) HUWE1-associated protein modifying stress responses 1 isoform X1\tK27699 HAPSTR1; HUWE1-associated protein modifying stress responses 1"
				}
				]
			}
			]
		},
		{
			"name":"U-box type E3",
			"children":[
			{
				"name":"134524936 UBE4A; (RefSeq) ubiquitin conjugation factor E4 A isoform X1\tK10596 UBE4A; ubiquitin conjugation factor E4 A [EC:2.3.2.27]"
			},
			{
				"name":"134524006 UBE4B; (RefSeq) ubiquitin conjugation factor E4 B isoform X1\tK10597 UBE4B; ubiquitin conjugation factor E4 B [EC:2.3.2.27]"
			},
			{
				"name":"134519878 STUB1; (RefSeq) E3 ubiquitin-protein ligase CHIP\tK09561 STUB1; STIP1 homology and U-box containing protein 1 [EC:2.3.2.27]"
			},
			{
				"name":"134522762 PPIL2; (RefSeq) RING-type E3 ubiquitin-protein ligase PPIL2\tK10598 PPIL2; peptidyl-prolyl cis-trans isomerase-like 2 [EC:5.2.1.8]"
			},
			{
				"name":"134514456 PRPF19; (RefSeq) pre-mRNA-processing factor 19\tK10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]"
			},
			{
				"name":"134509665 LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase RBBP6-like\tK10624 RBBP6; E3 ubiquitin-protein ligase RBBP6 [EC:2.3.2.27]"
			},
			{
				"name":"134520150 RBBP6; (RefSeq) E3 ubiquitin-protein ligase RBBP6 isoform X1\tK10624 RBBP6; E3 ubiquitin-protein ligase RBBP6 [EC:2.3.2.27]"
			},
			{
				"name":"134515958 UBOX5; (RefSeq) RING finger protein 37\tK10600 UBOX5; U-box domain-containing protein 5 [EC:2.3.2.27]"
			}
			]
		},
		{
			"name":"Single Ring-finger type E3",
			"children":[
			{
				"name":"BRE1 proteins",
				"children":[
				{
					"name":"134508373 RNF20; (RefSeq) E3 ubiquitin-protein ligase BRE1A\tK10696 BRE1; E3 ubiquitin-protein ligase BRE1 [EC:2.3.2.27]"
				}
				]
			},
			{
				"name":"CBL proteins",
				"children":[
				{
					"name":"134524927 CBL; (RefSeq) E3 ubiquitin-protein ligase CBL\tK04707 CBL; E3 ubiquitin-protein ligase CBL [EC:2.3.2.27]"
				},
				{
					"name":"134522216 CBLB; (RefSeq) E3 ubiquitin-protein ligase CBL-B isoform X1\tK22517 CBLB; E3 ubiquitin-protein ligase CBL-B [EC:2.3.2.27]"
				}
				]
			},
			{
				"name":"SINA (Seven in absentia) proteins",
				"children":[
				{
					"name":"134515441 SIAH1; (RefSeq) E3 ubiquitin-protein ligase SIAH1 isoform X1\tK04506 SIAH1; E3 ubiquitin-protein ligase SIAH1 [EC:2.3.2.27]"
				},
				{
					"name":"134517385 SIAH2; (RefSeq) E3 ubiquitin-protein ligase SIAH2\tK08742 SIAH2; E3 ubiquitin-protein ligase SIAH2 [EC:2.3.2.27]"
				}
				]
			},
			{
				"name":"Ligand of Numb proteins",
				"children":[
				{
					"name":"134514252 LNX2; (RefSeq) ligand of Numb protein X 2 isoform X1\tK10692 LNX1_2; ligand of Numb protein X 1\/2 [EC:2.3.2.27]"
				},
				{
					"name":"134516357 LNX1; (RefSeq) E3 ubiquitin-protein ligase LNX isoform X1\tK10692 LNX1_2; ligand of Numb protein X 1\/2 [EC:2.3.2.27]"
				},
				{
					"name":"134520958 ligand of Numb protein X 2-like\tK10692 LNX1_2; ligand of Numb protein X 1\/2 [EC:2.3.2.27]"
				},
				{
					"name":"134510176 PDZRN4; (RefSeq) PDZ domain-containing RING finger protein 4 isoform X1\tK15682 PDZRN3_4; ligand of Numb protein X 3\/4 [EC:2.3.2.27]"
				},
				{
					"name":"134521683 PDZRN3; (RefSeq) E3 ubiquitin-protein ligase PDZRN3 isoform X1\tK15682 PDZRN3_4; ligand of Numb protein X 3\/4 [EC:2.3.2.27]"
				}
				]
			},
			{
				"name":"March proteins",
				"children":[
				{
					"name":"134515844 MARCHF1; (RefSeq) E3 ubiquitin-protein ligase MARCHF1 isoform X1\tK10656 MARCH1_8; E3 ubiquitin-protein ligase MARCH1\/8 [EC:2.3.2.27]"
				},
				{
					"name":"134517153 MARCHF8; (RefSeq) E3 ubiquitin-protein ligase MARCHF8 isoform X1\tK10656 MARCH1_8; E3 ubiquitin-protein ligase MARCH1\/8 [EC:2.3.2.27]"
				},
				{
					"name":"134508820 MARCHF3; (RefSeq) E3 ubiquitin-protein ligase MARCHF3\tK10657 MARCH2_3; E3 ubiquitin-protein ligase MARCH2\/3 [EC:2.3.2.27]"
				},
				{
					"name":"134526500 MARCHF2; (RefSeq) E3 ubiquitin-protein ligase MARCHF2\tK10657 MARCH2_3; E3 ubiquitin-protein ligase MARCH2\/3 [EC:2.3.2.27]"
				},
				{
					"name":"134510720 MARCHF11; (RefSeq) E3 ubiquitin-protein ligase MARCHF11\tK10659 MARCH4_9_11; E3 ubiquitin-protein ligase MARCH4\/9\/11 [EC:2.3.2.27]"
				},
				{
					"name":"134518115 MARCHF4; (RefSeq) E3 ubiquitin-protein ligase MARCHF4 isoform X1\tK10659 MARCH4_9_11; E3 ubiquitin-protein ligase MARCH4\/9\/11 [EC:2.3.2.27]"
				},
				{
					"name":"134517812 MARCHF5; (RefSeq) E3 ubiquitin-protein ligase MARCHF5 isoform X1\tK10660 MARCH5; E3 ubiquitin-protein ligase MARCH5 [EC:2.3.2.27]"
				},
				{
					"name":"134511734 MARCHF6; (RefSeq) E3 ubiquitin-protein ligase MARCHF6 isoform X1\tK10661 MARCH6; E3 ubiquitin-protein ligase MARCH6 [EC:2.3.2.27]"
				},
				{
					"name":"134518289 MARCHF7; (RefSeq) E3 ubiquitin-protein ligase MARCHF7 isoform X1\tK10662 MARCH7; E3 ubiquitin-protein ligase MARCH7 [EC:2.3.2.27]"
				}
				]
			},
			{
				"name":"MDM2\/MDM4 proteins",
				"children":[
				{
					"name":"134510104 MDM2; (RefSeq) E3 ubiquitin-protein ligase Mdm2 isoform X1\tK06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]"
				},
				{
					"name":"134525748 MDM4; (RefSeq) protein Mdm4\tK10127 MDM4; protein Mdm4"
				}
				]
			},
			{
				"name":"NFX1 proteins",
				"children":[
				{
					"name":"134511547 NFX1; (RefSeq) transcriptional repressor NF-X1 isoform X1\tK12236 NFX1; transcriptional repressor NF-X1"
				},
				{
					"name":"134516015 NFXL1; (RefSeq) NF-X1-type zinc finger protein NFXL1\tK15683 NFXL1; NF-X1-type zinc finger protein NFXL1"
				}
				]
			},
			{
				"name":"Pellino proteins",
				"children":[
				{
					"name":"134512718 PELI1; (RefSeq) E3 ubiquitin-protein ligase pellino homolog 1 isoform X1\tK11964 PELI; pellino [EC:2.3.2.27]"
				},
				{
					"name":"134514876 PELI2; (RefSeq) E3 ubiquitin-protein ligase pellino homolog 2 isoform X1\tK11964 PELI; pellino [EC:2.3.2.27]"
				}
				]
			},
			{
				"name":"Peripheral membrane proteins",
				"children":[
				{
					"name":"134524031 PEX10; (RefSeq) peroxisome biogenesis factor 10\tK13346 PEX10; peroxin-10 [EC:2.3.2.27]"
				},
				{
					"name":"134518445 PEX12; (RefSeq) peroxisome assembly protein 12\tK13345 PEX12; peroxin-12"
				},
				{
					"name":"134512064 PEX2; (RefSeq) peroxisome biogenesis factor 2\tK06664 PEX2; peroxin-2 [EC:2.3.2.27 2.3.2.36]"
				}
				]
			},
			{
				"name":"RBR proteins",
				"children":[
				{
					"name":"134513086 PRKN; (RefSeq) E3 ubiquitin-protein ligase parkin isoform X1\tK04556 PARK2; parkin [EC:2.3.2.31]"
				},
				{
					"name":"134511209 ANKIB1; (RefSeq) ankyrin repeat and IBR domain-containing protein 1 isoform X1\tK11967 ANKIB1; ankyrin repeat and IBR domain-containing protein 1 [EC:2.3.2.31]"
				},
				{
					"name":"134520397 ARIH1; (RefSeq) E3 ubiquitin-protein ligase ARIH1\tK11968 ARIH1; ariadne-1 [EC:2.3.2.31]"
				},
				{
					"name":"134521656 ARIH2; (RefSeq) E3 ubiquitin-protein ligase ARIH2 isoform X1\tK11969 ARIH2; ariadne-2 [EC:2.3.2.31]"
				},
				{
					"name":"134512323 SHARPIN; (RefSeq) LOW QUALITY PROTEIN: sharpin\tK10630 RBCK1; RanBP-type and C3HC4-type zinc finger-containing protein 1 [EC:2.3.2.31]"
				},
				{
					"name":"134521818 RNF14; (RefSeq) E3 ubiquitin-protein ligase RNF14 isoform X1\tK11971 RNF14; E3 ubiquitin-protein ligase RNF14 [EC:2.3.2.31]"
				},
				{
					"name":"134512159 RNF19A; (RefSeq) E3 ubiquitin-protein ligase RNF19A\tK11972 RNF19A; E3 ubiquitin-protein ligase RNF19A [EC:2.3.2.31]"
				},
				{
					"name":"134513731 E3 ubiquitin-protein ligase RNF19B-like isoform X1\tK11973 RNF19B; E3 ubiquitin-protein ligase RNF19B [EC:2.3.2.31]"
				},
				{
					"name":"134525295 RNF19B; (RefSeq) E3 ubiquitin-protein ligase RNF19B\tK11973 RNF19B; E3 ubiquitin-protein ligase RNF19B [EC:2.3.2.31]"
				},
				{
					"name":"134518168 RFFL; (RefSeq) E3 ubiquitin-protein ligase rififylin isoform X1\tK20804 RNF34; E3 ubiquitin-protein ligase RNF34 [EC:2.3.2.31]"
				},
				{
					"name":"134523019 RNF34; (RefSeq) E3 ubiquitin-protein ligase RNF34 isoform X1\tK20804 RNF34; E3 ubiquitin-protein ligase RNF34 [EC:2.3.2.31]"
				},
				{
					"name":"134511598 RNF144B; (RefSeq) E3 ubiquitin-protein ligase RNF144B\tK11975 RNF144; E3 ubiquitin-protein ligase RNF144 [EC:2.3.2.31]"
				},
				{
					"name":"134513538 RNF144A; (RefSeq) E3 ubiquitin-protein ligase RNF144A\tK11975 RNF144; E3 ubiquitin-protein ligase RNF144 [EC:2.3.2.31]"
				},
				{
					"name":"134517325 RNF168; (RefSeq) E3 ubiquitin-protein ligase RNF168\tK20779 RNF168; E3 ubiquitin-protein ligase RNF168 [EC:2.3.2.31]"
				},
				{
					"name":"134512488 RNF169; (RefSeq) E3 ubiquitin-protein ligase RNF169\tK20805 RNF169; E3 ubiquitin-protein ligase RNF169 [EC:2.3.2.31]"
				},
				{
					"name":"134519730 RNF216; (RefSeq) E3 ubiquitin-protein ligase RNF216\tK11976 RNF216; E3 ubiquitin-protein ligase RNF216 [EC:2.3.2.31]"
				},
				{
					"name":"134513258 RNF217; (RefSeq) E3 ubiquitin-protein ligase RNF217\tK11977 RNF217; E3 ubiquitin-protein ligase RNF217 [EC:2.3.2.31]"
				}
				]
			},
			{
				"name":"TRAF proteins",
				"children":[
				{
					"name":"134523644 TRAF2; (RefSeq) TNF receptor-associated factor 2 isoform X1\tK03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]"
				},
				{
					"name":"134512784 TRAF5; (RefSeq) TNF receptor-associated factor 5\tK09849 TRAF5; TNF receptor-associated factor 5"
				},
				{
					"name":"134514724 TRAF6; (RefSeq) TNF receptor-associated factor 6\tK03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]"
				},
				{
					"name":"134519664 TRAF7; (RefSeq) E3 ubiquitin-protein ligase TRAF7 isoform X1\tK10646 TRAF7; E3 ubiquitin-protein ligase TRAF7 [EC:2.3.2.27]"
				}
				]
			},
			{
				"name":"TRIM\/RBCC proteins",
				"children":[
				{
					"name":"134520570 MID2; (RefSeq) probable E3 ubiquitin-protein ligase MID2\tK10647 TRIM1; midline 2 [EC:2.3.2.27]"
				},
				{
					"name":"134512916 TRIM3; (RefSeq) LOW QUALITY PROTEIN: tripartite motif-containing protein 3\tK11997 TRIM2_3; tripartite motif-containing protein 2\/3"
				},
				{
					"name":"134515972 TRIM2; (RefSeq) tripartite motif-containing protein 2 isoform X1\tK11997 TRIM2_3; tripartite motif-containing protein 2\/3"
				},
				{
					"name":"134507812 E3 ubiquitin-protein ligase TRIM7-like\tK12000 TRIM7; tripartite motif-containing protein 7"
				},
				{
					"name":"134507830 E3 ubiquitin-protein ligase TRIM7-like isoform X1\tK12000 TRIM7; tripartite motif-containing protein 7"
				},
				{
					"name":"134507880 E3 ubiquitin-protein ligase TRIM7-like\tK12000 TRIM7; tripartite motif-containing protein 7"
				},
				{
					"name":"134510951 E3 ubiquitin-protein ligase TRIM7-like isoform X1\tK12000 TRIM7; tripartite motif-containing protein 7"
				},
				{
					"name":"134517610 TRIM8; (RefSeq) E3 ubiquitin-protein ligase TRIM8\tK12001 TRIM8; tripartite motif-containing protein 8 [EC:2.3.2.27]"
				},
				{
					"name":"134513054 TRIM67; (RefSeq) tripartite motif-containing protein 67 isoform X1\tK10649 TRIM9_67; tripartite motif-containing protein 9\/67"
				},
				{
					"name":"134515168 TRIM9; (RefSeq) E3 ubiquitin-protein ligase TRIM9 isoform X1\tK10649 TRIM9_67; tripartite motif-containing protein 9\/67"
				},
				{
					"name":"134515194 TRIM13; (RefSeq) E3 ubiquitin-protein ligase TRIM13 isoform X1\tK12003 TRIM13; tripartite motif-containing protein 13 [EC:2.3.2.27]"
				},
				{
					"name":"134508271 TRIM14; (RefSeq) tripartite motif-containing protein 14\tK12004 TRIM14; tripartite motif-containing protein 14"
				},
				{
					"name":"134518547 MID1; (RefSeq) E3 ubiquitin-protein ligase Midline-1\tK08285 TRIM18; midline 1 [EC:2.3.2.27]"
				},
				{
					"name":"134508981 TRIM23; (RefSeq) E3 ubiquitin-protein ligase TRIM23 isoform X1\tK07963 TRIM23; tripartite motif-containing protein 23 [EC:2.3.2.27]"
				},
				{
					"name":"134508531 TRIM24; (RefSeq) transcription intermediary factor 1-alpha isoform X1\tK08881 TRIM24; tripartite motif-containing protein 24 [EC:2.3.2.27]"
				},
				{
					"name":"134523506 TRIM25; (RefSeq) E3 ubiquitin\/ISG15 ligase TRIM25\tK10652 TRIM25; tripartite motif-containing protein 25 [EC:2.3.2.27]"
				},
				{
					"name":"134507739 TRIM28; (RefSeq) transcription intermediary factor 1-beta isoform X1\tK08882 TRIM28; tripartite motif-containing protein 28 [EC:2.3.2.27]"
				},
				{
					"name":"134524942 TRIM29; (RefSeq) tripartite motif-containing protein 29 isoform X1\tK12010 TRIM29; tripartite motif-containing protein 29"
				},
				{
					"name":"134523629 TRIM32; (RefSeq) E3 ubiquitin-protein ligase TRIM32 isoform X1\tK10607 TRIM32; tripartite motif-containing protein 32 [EC:2.3.2.27]"
				},
				{
					"name":"134525500 TRIM33; (RefSeq) E3 ubiquitin-protein ligase TRIM33\tK08883 TRIM33; tripartite motif-containing protein 33 [EC:2.3.2.27]"
				},
				{
					"name":"134513685 TRIM35; (RefSeq) E3 ubiquitin-protein ligase TRIM35\tK12012 TRIM35; tripartite motif-containing protein 35"
				},
				{
					"name":"134508875 TRIM36; (RefSeq) E3 ubiquitin-protein ligase TRIM36 isoform X1\tK12013 TRIM36; tripartite motif-containing protein 36 [EC:2.3.2.27]"
				},
				{
					"name":"134519024 TRIM37; (RefSeq) E3 ubiquitin-protein ligase TRIM37 isoform X1\tK10608 TRIM37; tripartite motif-containing protein 37 [EC:2.3.2.27]"
				},
				{
					"name":"134507805 LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase TRIM39-like\tK12015 TRIM39; tripartite motif-containing protein 39 \/ bloodthirsty-related gene family protein [EC:2.3.2.27]"
				},
				{
					"name":"134507819 E3 ubiquitin-protein ligase TRIM39-like\tK12015 TRIM39; tripartite motif-containing protein 39 \/ bloodthirsty-related gene family protein [EC:2.3.2.27]"
				},
				{
					"name":"134518760 E3 ubiquitin-protein ligase TRIM39-like\tK12015 TRIM39; tripartite motif-containing protein 39 \/ bloodthirsty-related gene family protein [EC:2.3.2.27]"
				},
				{
					"name":"134507801 TRIM41; (RefSeq) E3 ubiquitin-protein ligase TRIM41\tK12017 TRIM41; tripartite motif-containing protein 41 [EC:2.3.2.27]"
				},
				{
					"name":"134517870 TRIM42; (RefSeq) LOW QUALITY PROTEIN: tripartite motif-containing protein 42\tK12018 TRIM42; tripartite motif-containing protein 42"
				},
				{
					"name":"134523520 TRIM45; (RefSeq) E3 ubiquitin-protein ligase TRIM45\tK12021 TRIM45; tripartite motif-containing protein 45"
				},
				{
					"name":"134525873 TRIM46; (RefSeq) tripartite motif-containing protein 46\tK12022 TRIM46; tripartite motif-containing protein 46"
				},
				{
					"name":"134523430 TRIM47; (RefSeq) E3 ubiquitin-protein ligase TRIM47\tK12023 TRIM47; tripartite motif-containing protein 47"
				},
				{
					"name":"134518763 TRIM50; (RefSeq) E3 ubiquitin-protein ligase TRIM50\tK12024 TRIM50_73_74; tripartite motif-containing protein 50\/73\/74"
				},
				{
					"name":"134512500 TRIM54; (RefSeq) tripartite motif-containing protein 54 isoform X1\tK10653 TRIM54; tripartite motif-containing protein 54"
				},
				{
					"name":"134512027 TRIM55; (RefSeq) tripartite motif-containing protein 55 isoform X1\tK10654 TRIM55; tripartite motif-containing protein 55"
				},
				{
					"name":"134517661 TRIM59; (RefSeq) tripartite motif-containing protein 59 isoform X1\tK12028 TRIM59; tripartite motif-containing protein 59"
				},
				{
					"name":"134524078 E3 ubiquitin-protein ligase TRIM62\tK12030 TRIM62; tripartite motif-containing protein 62 [EC:2.3.2.27]"
				},
				{
					"name":"134525335 TRIM63; (RefSeq) E3 ubiquitin-protein ligase TRIM63 isoform X1\tK10655 TRIM63; tripartite motif-containing protein 63 [EC:2.3.2.27]"
				},
				{
					"name":"134523536 TRIM65; (RefSeq) E3 ubiquitin-protein ligase TRIM65 isoform X1\tK12031 TRIM65; tripartite motif-containing protein 65"
				},
				{
					"name":"134514602 TRIM66; (RefSeq) tripartite motif-containing protein 66 isoform X1\tK12032 TRIM66; tripartite motif-containing protein 66"
				},
				{
					"name":"134511391 TRIM71; (RefSeq) E3 ubiquitin-protein ligase TRIM71\tK12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]"
				}
				]
			},
			{
				"name":"UBR box proteins",
				"children":[
				{
					"name":"134514264 UBR1; (RefSeq) E3 ubiquitin-protein ligase UBR1 isoform X1\tK10625 UBR1; E3 ubiquitin-protein ligase UBR1 [EC:2.3.2.27]"
				},
				{
					"name":"134512799 UBR2; (RefSeq) E3 ubiquitin-protein ligase UBR2 isoform X1\tK10626 UBR2; E3 ubiquitin-protein ligase UBR2 [EC:2.3.2.27]"
				},
				{
					"name":"134518086 UBR3; (RefSeq) E3 ubiquitin-protein ligase UBR3 isoform X1\tK11978 UBR3; E3 ubiquitin-protein ligase UBR3 [EC:2.3.2.27]"
				},
				{
					"name":"134524254 UBR4; (RefSeq) E3 ubiquitin-protein ligase UBR4 isoform X1\tK10691 UBR4; E3 ubiquitin-protein ligase UBR4 [EC:2.3.2.27]"
				},
				{
					"name":"134514738 UBR7; (RefSeq) putative E3 ubiquitin-protein ligase UBR7\tK11979 UBR7; E3 ubiquitin-protein ligase UBR7 [EC:2.3.2.27]"
				}
				]
			},
			{
				"name":"ATL proteins"
			},
			{
				"name":"Other single Ring-finger type E3",
				"children":[
				{
					"name":"134515349 AMFR; (RefSeq) E3 ubiquitin-protein ligase AMFR isoform X1\tK10636 AMFR; E3 ubiquitin-protein ligase AMFR [EC:2.3.2.36]"
				},
				{
					"name":"134517985 AIRE; (RefSeq) autoimmune regulator isoform X1\tK10603 AIRE; autoimmune regulator"
				},
				{
					"name":"134520074 BFAR; (RefSeq) bifunctional apoptosis regulator\tK15684 BFAR; bifunctional apoptosis regulator"
				},
				{
					"name":"134513373 BIRC2; (RefSeq) baculoviral IAP repeat-containing protein 2\tK16060 BIRC2_3; baculoviral IAP repeat-containing protein 2\/3"
				},
				{
					"name":"134520766 XIAP; (RefSeq) E3 ubiquitin-protein ligase XIAP isoform X1\tK04725 XIAP; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]"
				},
				{
					"name":"134522267 BIRC7; (RefSeq) baculoviral IAP repeat-containing protein 7 isoform X1\tK16061 BIRC7_8; baculoviral IAP repeat-containing protein 7\/8"
				},
				{
					"name":"134523105 BRAP; (RefSeq) BRCA1-associated protein\tK10632 BRAP; BRCA1-associated protein [EC:2.3.2.27]"
				},
				{
					"name":"134524464 BRCA1; (RefSeq) breast cancer type 1 susceptibility protein isoform X1\tK10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]"
				},
				{
					"name":"134510300 CBLL1; (RefSeq) E3 ubiquitin-protein ligase Hakai isoform X1\tK15685 CBLL1; E3 ubiquitin-protein ligase Hakai [EC:2.3.2.27]"
				},
				{
					"name":"134522775 CHFR; (RefSeq) E3 ubiquitin-protein ligase CHFR\tK10644 CHFR; E3 ubiquitin-protein ligase CHFR [EC:2.3.2.27]"
				},
				{
					"name":"134509981 CNOT4; (RefSeq) CCR4-NOT transcription complex subunit 4 isoform X1\tK10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]"
				},
				{
					"name":"134526104 DCST1; (RefSeq) E3 ubiquitin-protein ligase DCST1\tK22375 DCST1; E3 ubiquitin-protein ligase DCST1 [EC:2.3.2.27]"
				},
				{
					"name":"134514444 DTX4; (RefSeq) E3 ubiquitin-protein ligase DTX4\tK06058 DTX; deltex [EC:2.3.2.27]"
				},
				{
					"name":"134518587 DTX3L; (RefSeq) E3 ubiquitin-protein ligase DTX3L\tK06058 DTX; deltex [EC:2.3.2.27]"
				},
				{
					"name":"134518682 DTX2; (RefSeq) probable E3 ubiquitin-protein ligase DTX2 isoform X1\tK06058 DTX; deltex [EC:2.3.2.27]"
				},
				{
					"name":"134522967 DTX1; (RefSeq) E3 ubiquitin-protein ligase DTX1\tK06058 DTX; deltex [EC:2.3.2.27]"
				},
				{
					"name":"134526814 DTX3; (RefSeq) probable E3 ubiquitin-protein ligase DTX3 isoform X1\tK06058 DTX; deltex [EC:2.3.2.27]"
				},
				{
					"name":"134513959 FANCL; (RefSeq) E3 ubiquitin-protein ligase FANCL\tK10606 FANCL; E3 ubiquitin-protein ligase FANCL [EC:2.3.2.27]"
				},
				{
					"name":"134508540 KCMF1; (RefSeq) E3 ubiquitin-protein ligase KCMF1 isoform X1\tK22376 KCMF1; E3 ubiquitin-protein ligase KCMF1 [EC:2.3.2.27]"
				},
				{
					"name":"134523672 LRSAM1; (RefSeq) E3 ubiquitin-protein ligase LRSAM1 isoform X1\tK10641 LRSAM1; E3 ubiquitin-protein ligase LRSAM1 [EC:2.3.2.27]"
				},
				{
					"name":"134521052 LTN1; (RefSeq) E3 ubiquitin-protein ligase listerin\tK22377 LTN1; E3 ubiquitin-protein ligase listerin [EC:2.3.2.27]"
				},
				{
					"name":"134508537 MAP3K1; (RefSeq) mitogen-activated protein kinase kinase kinase 1 isoform X1\tK04416 MAP3K1; mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25]"
				},
				{
					"name":"134508872 MEX3C; (RefSeq) RNA-binding E3 ubiquitin-protein ligase MEX3C\tK15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]"
				},
				{
					"name":"134520571 MEX3B; (RefSeq) RNA-binding protein MEX3B\tK15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]"
				},
				{
					"name":"134525891 MEX3A; (RefSeq) RNA-binding protein MEX3A\tK15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]"
				},
				{
					"name":"134526409 MEX3D; (RefSeq) RNA-binding protein MEX3D\tK15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]"
				},
				{
					"name":"134519604 MGRN1; (RefSeq) E3 ubiquitin-protein ligase MGRN1 isoform X1\tK10604 MGRN1; E3 ubiquitin-protein ligase MGRN1 [EC:2.3.2.27]"
				},
				{
					"name":"134511922 MIB1; (RefSeq) E3 ubiquitin-protein ligase MIB1 isoform X1\tK10645 MIB; E3 ubiquitin-protein ligase mind-bomb [EC:2.3.2.27]"
				},
				{
					"name":"134523966 MIB2; (RefSeq) E3 ubiquitin-protein ligase MIB2 isoform X1\tK10645 MIB; E3 ubiquitin-protein ligase mind-bomb [EC:2.3.2.27]"
				},
				{
					"name":"134508460 MKRN1; (RefSeq) E3 ubiquitin-protein ligase makorin-1\tK15687 MKRN; E3 ubiquitin-protein ligase makorin [EC:2.3.2.27]"
				},
				{
					"name":"134521678 MKRN2; (RefSeq) E3 ubiquitin-protein ligase makorin-2\tK15687 MKRN; E3 ubiquitin-protein ligase makorin [EC:2.3.2.27]"
				},
				{
					"name":"134525729 probable E3 ubiquitin-protein ligase makorin-1\tK15687 MKRN; E3 ubiquitin-protein ligase makorin [EC:2.3.2.27]"
				},
				{
					"name":"134517884 LOW QUALITY PROTEIN: mitochondrial ubiquitin ligase activator of nfkb 1-A-like\tK15688 MUL1; E3 ubiquitin-protein ligase MUL1 [EC:2.3.2.27]"
				},
				{
					"name":"134524250 MUL1; (RefSeq) mitochondrial ubiquitin ligase activator of NFKB 1\tK15688 MUL1; E3 ubiquitin-protein ligase MUL1 [EC:2.3.2.27]"
				},
				{
					"name":"134516055 MYCBP2; (RefSeq) E3 ubiquitin-protein ligase MYCBP2 isoform X1\tK10693 MYCBP2; RCR-type E3 ubiquitin transferase [EC:2.3.2.33]"
				},
				{
					"name":"134511614 MYLIP; (RefSeq) E3 ubiquitin-protein ligase MYLIP\tK10637 MYLIP; E3 ubiquitin-protein ligase MYLIP [EC:2.3.2.27]"
				},
				{
					"name":"134517647 NEURL1; (RefSeq) E3 ubiquitin-protein ligase NEURL1 isoform X1\tK01931 NEUR; protein neuralized [EC:2.3.2.27]"
				},
				{
					"name":"134522043 NEURL1B; (RefSeq) E3 ubiquitin-protein ligase NEURL1B isoform X1\tK01931 NEUR; protein neuralized [EC:2.3.2.27]"
				},
				{
					"name":"134511600 NHLRC1; (RefSeq) E3 ubiquitin-protein ligase NHLRC1\tK10602 NHLRC1; E3 ubiquitin-protein ligase NHLRC1 [EC:2.3.2.27]"
				},
				{
					"name":"134516131 OBI1; (RefSeq) ORC ubiquitin ligase 1\tK24091 OBI1; ORC ubiquitin ligase 1 [EC:2.3.2.27]"
				},
				{
					"name":"134508795 PJA2; (RefSeq) E3 ubiquitin-protein ligase Praja-2 isoform X1\tK10634 PJA2; E3 ubiquitin-protein ligase Praja2 [EC:2.3.2.27]"
				},
				{
					"name":"134521668 RAD18; (RefSeq) E3 ubiquitin-protein ligase RAD18 isoform X1\tK10627 RAD18; E3 ubiquitin-protein ligase RAD18 [EC:2.3.2.27]"
				},
				{
					"name":"134515103 RAG1; (RefSeq) V(D)J recombination-activating protein 1\tK10628 RAG1; V(D)J recombination-activating protein 1 [EC:2.3.2.27]"
				},
				{
					"name":"134516469 RCHY1; (RefSeq) RING finger and CHY zinc finger domain-containing protein 1\tK10144 RCHY1; RING finger and CHY zinc finger domain-containing protein 1 [EC:2.3.2.27]"
				},
				{
					"name":"134523703 RC3H2; (RefSeq) roquin-2 isoform X1\tK15690 RC3H; RING finger and CCCH-type zinc finger domain-containing protein"
				},
				{
					"name":"134519238 COP1; (RefSeq) E3 ubiquitin-protein ligase COP1 isoform X1\tK10143 RFWD2; E3 ubiquitin-protein ligase RFWD2 [EC:2.3.2.27]"
				},
				{
					"name":"134515328 RFWD3; (RefSeq) E3 ubiquitin-protein ligase RFWD3 isoform X1\tK15691 RFWD3; E3 ubiquitin-protein ligase RFWD3 [EC:2.3.2.27]"
				},
				{
					"name":"134507837 RING1; (RefSeq) E3 ubiquitin-protein ligase RING1\tK10695 RNF1_2; E3 ubiquitin-protein ligase RNF1\/2 [EC:2.3.2.27]"
				},
				{
					"name":"134519165 RNF2; (RefSeq) E3 ubiquitin-protein ligase RING2\tK10695 RNF1_2; E3 ubiquitin-protein ligase RNF1\/2 [EC:2.3.2.27]"
				},
				{
					"name":"134516061 RNF4; (RefSeq) E3 ubiquitin-protein ligase RNF4 isoform X1\tK22651 RNF4; E3 ubiquitin-protein ligase RNF4 [EC:2.3.2.27]"
				},
				{
					"name":"134522963 RNF185; (RefSeq) E3 ubiquitin-protein ligase RNF185\tK10666 RNF5_185; E3 ubiquitin-protein ligase RNF5\/185 [EC:2.3.2.27]"
				},
				{
					"name":"134514137 RNF6; (RefSeq) E3 ubiquitin-protein ligase RNF6 isoform X1\tK22753 RNF6; E3 ubiquitin-protein ligase RNF6 [EC:2.3.2.27]"
				},
				{
					"name":"134512884 RNF8; (RefSeq) E3 ubiquitin-protein ligase RNF8 isoform X1\tK10667 RNF8; E3 ubiquitin-protein ligase RNF8 [EC:2.3.2.27]"
				},
				{
					"name":"134522726 RNF10; (RefSeq) E3 ubiquitin-protein ligase RNF10\tK26979 RNF10; E3 ubiquitin-protein ligase RNF10 [EC:2.3.2.27]"
				},
				{
					"name":"134519561 RNF11; (RefSeq) RING finger protein 11\tK11980 RNF11; E3 ubiquitin-protein ligase RNF11"
				},
				{
					"name":"134520693 RLIM; (RefSeq) E3 ubiquitin-protein ligase RLIM isoform X1\tK16271 RLIM; E3 ubiquitin-protein ligase RLIM [EC:2.3.2.27]"
				},
				{
					"name":"134518017 RNF13; (RefSeq) E3 ubiquitin-protein ligase RNF13\tK15692 RNF13; E3 ubiquitin-protein ligase RNF13 [EC:2.3.2.27]"
				},
				{
					"name":"134518420 RNF25; (RefSeq) E3 ubiquitin-protein ligase RNF25 isoform X1\tK10640 RNF25; E3 ubiquitin-protein ligase RNF25 [EC:2.3.2.27]"
				},
				{
					"name":"134525016 RNF26; (RefSeq) E3 ubiquitin-protein ligase RNF26\tK15693 RNF26; E3 ubiquitin-protein ligase RNF26 [EC:2.3.2.27]"
				},
				{
					"name":"134508231 RNF38; (RefSeq) E3 ubiquitin-protein ligase RNF38 isoform X1\tK19041 RNF38_44; E3 ubiquitin-protein ligase RNF38\/44 [EC:2.3.2.27]"
				},
				{
					"name":"134522006 RNF44; (RefSeq) LOW QUALITY PROTEIN: RING finger protein 44\tK19041 RNF38_44; E3 ubiquitin-protein ligase RNF38\/44 [EC:2.3.2.27]"
				},
				{
					"name":"134526791 RNF41; (RefSeq) E3 ubiquitin-protein ligase NRDP1\tK11981 RNF41; E3 ubiquitin-protein ligase NRDP1 [EC:2.3.2.27]"
				},
				{
					"name":"134518737 RNF43; (RefSeq) E3 ubiquitin-protein ligase RNF43\tK15694 RNF43; E3 ubiquitin-protein ligase RNF43 [EC:2.3.2.27]"
				},
				{
					"name":"134516595 E3 ubiquitin-protein ligase RNF103 isoform X1\tK15695 RNF103; E3 ubiquitin-protein ligase RNF103 [EC:2.3.2.27]"
				},
				{
					"name":"134520518 RNF111; (RefSeq) E3 ubiquitin-protein ligase Arkadia isoform X1\tK10635 RNF111; E3 ubiquitin-protein ligase Arkadia [EC:2.3.2.27]"
				},
				{
					"name":"134522307 RNF114; (RefSeq) E3 ubiquitin-protein ligase RNF114\tK15697 RNF114; E3 ubiquitin-protein ligase RNF114 [EC:2.3.2.27]"
				},
				{
					"name":"134526006 RNF115; (RefSeq) E3 ubiquitin-protein ligase RNF115\tK11982 RNF115_126; E3 ubiquitin-protein ligase RNF115\/126 [EC:2.3.2.27]"
				},
				{
					"name":"134526264 RNF126; (RefSeq) E3 ubiquitin-protein ligase RNF126 isoform X1\tK11982 RNF115_126; E3 ubiquitin-protein ligase RNF115\/126 [EC:2.3.2.27]"
				},
				{
					"name":"134512612 RNF121; (RefSeq) E3 ubiquitin ligase RNF121 isoform X1\tK15698 RNF121_175; RING finger protein 121\/175"
				},
				{
					"name":"134516278 RNF175; (RefSeq) LOW QUALITY PROTEIN: RING finger protein 175\tK15698 RNF121_175; RING finger protein 121\/175"
				},
				{
					"name":"134526666 RNF122; (RefSeq) RING finger protein 122\tK15699 RNF122; RING finger protein 122"
				},
				{
					"name":"134521721 RNF123; (RefSeq) E3 ubiquitin-protein ligase RNF123 isoform X1\tK12169 KPC1; Kip1 ubiquitination-promoting complex protein 1 [EC:2.3.2.27]"
				},
				{
					"name":"134520733 RNF128; (RefSeq) E3 ubiquitin-protein ligase RNF128 isoform X1\tK10629 RNF128; E3 ubiquitin-protein ligase RNF128 [EC:2.3.2.27]"
				},
				{
					"name":"134521840 RNF130; (RefSeq) E3 ubiquitin-protein ligase RNF130 isoform X1\tK15701 RNF130; E3 ubiquitin-protein ligase RNF130 [EC:2.3.2.27]"
				},
				{
					"name":"134511953 RNF138; (RefSeq) E3 ubiquitin-protein ligase RNF138 isoform X1\tK10668 RNF138; E3 ubiquitin-protein ligase RNF138 [EC:2.3.2.27]"
				},
				{
					"name":"134512244 RNF139; (RefSeq) E3 ubiquitin-protein ligase RNF139\tK15703 RNF139; E3 ubiquitin-protein ligase RNF139 [EC:2.3.2.27]"
				},
				{
					"name":"134516580 RING finger protein 145-like isoform X1\tK23789 RNF145; E3 ubiquitin-protein ligase RNF145 [EC:2.3.2.27]"
				},
				{
					"name":"134522190 RNF145; (RefSeq) RING finger protein 145\tK23789 RNF145; E3 ubiquitin-protein ligase RNF145 [EC:2.3.2.27]"
				},
				{
					"name":"134513246 RNF146; (RefSeq) E3 ubiquitin-protein ligase RNF146\tK15700 RNF146; E3 ubiquitin-protein ligase RNF146 [EC:2.3.2.27]"
				},
				{
					"name":"134517662 RNF149; (RefSeq) E3 ubiquitin-protein ligase RNF149 isoform X1\tK15704 RNF149; E3 ubiquitin-protein ligase RNF149 [EC:2.3.2.27]"
				},
				{
					"name":"134523281 RNF157; (RefSeq) E3 ubiquitin ligase RNF157 isoform X1\tK25192 RNF157; E3 ubiquitin-protein ligase RNF157 [EC:2.3.2.27]"
				},
				{
					"name":"134508823 ARK2C; (RefSeq) E3 ubiquitin-protein ligase ARK2C isoform X1\tK17821 RNF165; E3 ubiquitin-protein ligase RNF165 [EC:2.3.2.27]"
				},
				{
					"name":"134515638 RNF166; (RefSeq) E3 ubiquitin-protein ligase RNF166 isoform X1\tK17044 RNF166; E3 ubiquitin-protein ligase RNF166 [EC:2.3.2.27]"
				},
				{
					"name":"134508714 RNF170; (RefSeq) E3 ubiquitin-protein ligase RNF170 isoform X1\tK15707 RNF170; E3 ubiquitin-protein ligase RNF170 [EC:2.3.2.27]"
				},
				{
					"name":"134520004 E3 ubiquitin-protein ligase RNF170-like isoform X1\tK15707 RNF170; E3 ubiquitin-protein ligase RNF170 [EC:2.3.2.27]"
				},
				{
					"name":"134508899 RNF180; (RefSeq) E3 ubiquitin-protein ligase RNF180 isoform X1\tK15708 RNF180; E3 ubiquitin-protein ligase RNF180 [EC:2.3.2.27]"
				},
				{
					"name":"134511612 RNF182; (RefSeq) E3 ubiquitin-protein ligase RNF182\tK11983 RNF182; E3 ubiquitin-protein ligase RNF182 [EC:2.3.2.27]"
				},
				{
					"name":"134522383 E3 ubiquitin-protein ligase RNF182-like\tK11983 RNF182; E3 ubiquitin-protein ligase RNF182 [EC:2.3.2.27]"
				},
				{
					"name":"134524125 RNF186; (RefSeq) E3 ubiquitin-protein ligase RNF186\tK25214 RNF186; E3 ubiquitin-protein ligase RNF186 [EC:2.3.2.27]"
				},
				{
					"name":"134509533 LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase rnf213-alpha-like\tK22754 RNF213; E3 ubiquitin-protein ligase RNF213 [EC:2.3.2.27]"
				},
				{
					"name":"134509688 E3 ubiquitin-protein ligase rnf213-alpha-like isoform X1\tK22754 RNF213; E3 ubiquitin-protein ligase RNF213 [EC:2.3.2.27]"
				},
				{
					"name":"134509689 E3 ubiquitin-protein ligase rnf213-alpha-like isoform X1\tK22754 RNF213; E3 ubiquitin-protein ligase RNF213 [EC:2.3.2.27]"
				},
				{
					"name":"134509691 E3 ubiquitin-protein ligase rnf213-alpha-like isoform X1\tK22754 RNF213; E3 ubiquitin-protein ligase RNF213 [EC:2.3.2.27]"
				},
				{
					"name":"134513595 E3 ubiquitin-protein ligase rnf213-alpha-like isoform X1\tK22754 RNF213; E3 ubiquitin-protein ligase RNF213 [EC:2.3.2.27]"
				},
				{
					"name":"134523204 RNF213; (RefSeq) E3 ubiquitin-protein ligase RNF213\tK22754 RNF213; E3 ubiquitin-protein ligase RNF213 [EC:2.3.2.27]"
				},
				{
					"name":"134519420 RNF220; (RefSeq) E3 ubiquitin-protein ligase RNF220 isoform X1\tK25174 RNF220; E3 ubiquitin-protein ligase RNF220 [EC:2.3.2.27]"
				},
				{
					"name":"134518941 RNFT1; (RefSeq) E3 ubiquitin-protein ligase RNFT1\tK22379 RNFT1; E3 ubiquitin-protein ligase RNFT1 [EC:2.3.2.27]"
				},
				{
					"name":"134523086 RNFT2; (RefSeq) E3 ubiquitin-protein ligase RNFT2 isoform X1\tK28516 RNFT2; E3 ubiquitin-protein ligase RNFT2"
				},
				{
					"name":"134513112 SHPRH; (RefSeq) E3 ubiquitin-protein ligase SHPRH isoform X1\tK15710 SHPRH; E3 ubiquitin-protein ligase SHPRH [EC:5.6.2.- 2.3.2.27]"
				},
				{
					"name":"134516474 SH3RF1; (RefSeq) E3 ubiquitin-protein ligase SH3RF1\tK12171 SH3RF; E3 ubiquitin-protein ligase SH3RF [EC:2.3.2.27]"
				},
				{
					"name":"134517243 SH3RF3; (RefSeq) E3 ubiquitin-protein ligase SH3RF3\tK12171 SH3RF; E3 ubiquitin-protein ligase SH3RF [EC:2.3.2.27]"
				},
				{
					"name":"134521994 SH3RF2; (RefSeq) E3 ubiquitin-protein ligase SH3RF2\tK12171 SH3RF; E3 ubiquitin-protein ligase SH3RF [EC:2.3.2.27]"
				},
				{
					"name":"134517794 HLTF; (RefSeq) helicase-like transcription factor isoform X1\tK15711 SMARCA3; SWI\/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A3 [EC:5.6.2. 2.3.2.27]"
				},
				{
					"name":"134508071 SYVN1; (RefSeq) E3 ubiquitin-protein ligase synoviolin\tK10601 SYVN1; E3 ubiquitin-protein ligase synoviolin [EC:2.3.2.27]"
				},
				{
					"name":"134516389 TMEM129; (RefSeq) E3 ubiquitin-protein ligase TM129\tK22380 TMEM129; E3 ubiquitin-protein ligase TM129 [EC:2.3.2.27]"
				},
				{
					"name":"134508629 TOPORS; (RefSeq) E3 ubiquitin-protein ligase Topors\tK10631 TOPORS; E3 ubiquitin-protein ligase Topors [EC:2.3.2.27]"
				},
				{
					"name":"134521441 TRAIP; (RefSeq) E3 ubiquitin-protein ligase TRAIP isoform X1\tK11985 TRAIP; TRAF-interacting protein [EC:2.3.2.27]"
				},
				{
					"name":"134520367 TTC3; (RefSeq) E3 ubiquitin-protein ligase TTC3 isoform X1\tK15712 TTC3; E3 ubiquitin-protein ligase TTC3 [EC:2.3.2.27]"
				},
				{
					"name":"134526320 UHRF1; (RefSeq) E3 ubiquitin-protein ligase UHRF1\tK10638 UHRF1; E3 ubiquitin-protein ligase UHRF1 [EC:2.3.2.27]"
				},
				{
					"name":"134508322 UHRF2; (RefSeq) E3 ubiquitin-protein ligase UHRF2 isoform X1\tK15713 UHRF2; E3 ubiquitin-protein ligase UHRF2 [EC:2.3.2.27]"
				},
				{
					"name":"134520227 UNKL; (RefSeq) putative E3 ubiquitin-protein ligase UNKL isoform X1\tK23047 UNKL; E3 ubiquitin-protein ligase UNKL [EC:2.3.2.27]"
				},
				{
					"name":"134519643 ZNF598; (RefSeq) E3 ubiquitin-protein ligase ZNF598 isoform X1\tK22381 ZNF598; E3 ubiquitin-protein ligase ZNF598 [EC:2.3.2.27]"
				},
				{
					"name":"134514170 ZFP91; (RefSeq) E3 ubiquitin-protein ligase ZFP91 isoform X1\tK25175 ZFP91; E3 ubiquitin-protein ligase ZFP91 [EC:2.3.2.27]"
				},
				{
					"name":"134511400 ZNRF2; (RefSeq) E3 ubiquitin-protein ligase ZNRF2\tK10694 ZNRF1_2; E3 ubiquitin-protein ligase ZNRF1\/2 [EC:2.3.2.27]"
				},
				{
					"name":"134515332 ZNRF1; (RefSeq) LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase ZNRF1\tK10694 ZNRF1_2; E3 ubiquitin-protein ligase ZNRF1\/2 [EC:2.3.2.27]"
				},
				{
					"name":"134522958 ZNRF3; (RefSeq) E3 ubiquitin-protein ligase ZNRF3\tK16273 ZNRF3; E3 ubiquitin-protein ligase ZNRF3 [EC:2.3.2.27]"
				}
				]
			}
			]
		},
		{
			"name":"Atypical E3",
			"children":[
			{
				"name":"134521831 JADE2; (RefSeq) E3 ubiquitin-protein ligase Jade-2 isoform X1\tK22155 JADE2; E3 ubiquitin-protein ligase Jade-2 [EC:2.3.2.27]"
			},
			{
				"name":"134520146 E4F1; (RefSeq) transcription factor E4F1 isoform X1\tK22401 E4F1; transcription factor E4F1 \/ E3 ubiquitin-protein ligase [EC:2.3.2.27]"
			},
			{
				"name":"134519899 NSMCE1; (RefSeq) non-structural maintenance of chromosomes element 1 homolog\tK22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27]"
			},
			{
				"name":"134514788 IRF2BPL; (RefSeq) probable E3 ubiquitin-protein ligase IRF2BPL\tK22383 IRF2BP; interferon regulatory factor 2-binding protein"
			}
			]
		},
		{
			"name":"UBL E3 ligases",
			"children":[
			{
				"name":"134509872 RBX1; (RefSeq) E3 ubiquitin-protein ligase RBX1\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
			},
			{
				"name":"134508629 TOPORS; (RefSeq) E3 ubiquitin-protein ligase Topors\tK10631 TOPORS; E3 ubiquitin-protein ligase Topors [EC:2.3.2.27]"
			},
			{
				"name":"134517254 RGPD4; (RefSeq) ranBP2-like and GRIP domain-containing protein 4 isoform X1\tK12172 RANBP2; E3 SUMO-protein ligase RanBP2 [EC:2.3.2.-]"
			},
			{
				"name":"134520639 PIAS1; (RefSeq) E3 SUMO-protein ligase PIAS1 isoform X1\tK04706 PIAS1; E3 SUMO-protein ligase PIAS1 [EC:2.3.2.-]"
			},
			{
				"name":"134508183 PIAS2; (RefSeq) E3 SUMO-protein ligase PIAS2 isoform X1\tK16063 PIAS2; E3 SUMO-protein ligase PIAS2 [EC:2.3.2.-]"
			},
			{
				"name":"134525986 PIAS3; (RefSeq) E3 SUMO-protein ligase PIAS3 isoform X1\tK16064 PIAS3; E3 SUMO-protein ligase PIAS3 [EC:2.3.2.-]"
			},
			{
				"name":"134526358 PIAS4; (RefSeq) E3 SUMO-protein ligase PIAS4\tK16065 PIAS4; E3 SUMO-protein ligase PIAS4 [EC:2.3.2.27]"
			},
			{
				"name":"134520695 protein PML-like\tK10054 PML; E3 SUMO-protein ligase PML [EC:2.3.2.-]"
			},
			{
				"name":"134521130 protein PML-like\tK10054 PML; E3 SUMO-protein ligase PML [EC:2.3.2.-]"
			},
			{
				"name":"134523182 CBX4; (RefSeq) E3 SUMO-protein ligase CBX4\tK11452 CBX4; E3 SUMO-protein ligase CBX4 [EC:2.3.2.-]"
			},
			{
				"name":"134512251 NSMCE2; (RefSeq) E3 SUMO-protein ligase NSE2\tK22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]"
			},
			{
				"name":"134518262 ZBED1; (RefSeq) E3 SUMO-protein ligase ZBED1\tK24637 ZBED1; zinc finger BED domain-containing protein 1 (E3 SUMO-protein ligase ZBED1) [EC:2.3.2.-]"
			},
			{
				"name":"134513482 E3 SUMO-protein ligase ZNF451-like isoform X1\tK25176 ZNF451; E3 SUMO-protein ligase ZNF451 [EC:2.3.2.-]"
			},
			{
				"name":"134516003 probable E3 ubiquitin-protein ligase HERC4 isoform X1\tK22372 HERC5_6; E3 ISG15--protein ligase [EC:2.3.2.-]"
			},
			{
				"name":"134513367 UFL1; (RefSeq) E3 UFM1-protein ligase 1\tK22755 UFL1; E3 UFM1-protein ligase 1 [EC:2.3.2.-]"
			},
			{
				"name":"134517107 DCUN1D2; (RefSeq) DCN1-like protein 2 isoform X1\tK17822 DCUN1D1_2; DCN1-like protein 1\/2"
			},
			{
				"name":"134517474 DCUN1D1; (RefSeq) DCN1-like protein 1\tK17822 DCUN1D1_2; DCN1-like protein 1\/2"
			},
			{
				"name":"134519914 DCUN1D3; (RefSeq) DCN1-like protein 3\tK17823 DCUN1D3; DCN1-like protein 3"
			},
			{
				"name":"134513400 DCUN1D5; (RefSeq) DCN1-like protein 5\tK17824 DCUN1D4_5; DCN1-like protein 4\/5"
			},
			{
				"name":"134515791 DCUN1D4; (RefSeq) DCN1-like protein 4 isoform X1\tK17824 DCUN1D4_5; DCN1-like protein 4\/5"
			}
			]
		},
		{
			"name":"Multi subunit type E3",
			"children":[
			{
				"name":"SCF complex",
				"children":[
				{
					"name":"Ring finger protein",
					"children":[
					{
						"name":"134509872 RBX1; (RefSeq) E3 ubiquitin-protein ligase RBX1\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
					}
					]
				},
				{
					"name":"Cullin",
					"children":[
					{
						"name":"134511539 CUL1; (RefSeq) cullin-1\tK03347 CUL1; cullin 1"
					}
					]
				},
				{
					"name":"Adaptor protein",
					"children":[
					{
						"name":"134521747 SKP1; (RefSeq) S-phase kinase-associated protein 1\tK03094 SKP1; S-phase kinase-associated protein 1"
					}
					]
				},
				{
					"name":"Target recognizing subunit (F-box)",
					"children":[
					{
						"name":"134516870 BTRC; (RefSeq) F-box\/WD repeat-containing protein 1A isoform X1\tK03362 FBXW1_11; F-box and WD-40 domain protein 1\/11"
					},
					{
						"name":"134521821 FBXW11; (RefSeq) F-box\/WD repeat-containing protein 11 isoform X1\tK03362 FBXW1_11; F-box and WD-40 domain protein 1\/11"
					},
					{
						"name":"134523656 FBXW2; (RefSeq) F-box\/WD repeat-containing protein 2 isoform X1\tK10261 FBXW2; F-box and WD-40 domain protein 2"
					},
					{
						"name":"134517798 FBXW4; (RefSeq) LOW QUALITY PROTEIN: F-box\/WD repeat-containing protein 4\tK10262 FBXW4; F-box and WD-40 domain protein 4"
					},
					{
						"name":"134523683 FBXW5; (RefSeq) F-box\/WD repeat-containing protein 5\tK10263 FBXW5; F-box and WD-40 domain protein 5"
					},
					{
						"name":"134512944 RRP8; (RefSeq) ribosomal RNA-processing protein 8 isoform X1\tK10260 FBXW7; F-box and WD-40 domain protein 7"
					},
					{
						"name":"134516121 FBXW7; (RefSeq) F-box\/WD repeat-containing protein 7 isoform X1\tK10260 FBXW7; F-box and WD-40 domain protein 7"
					},
					{
						"name":"134522722 FBXW8; (RefSeq) F-box\/WD repeat-containing protein 8\tK10264 FBXW8; F-box and WD-40 domain protein 8"
					},
					{
						"name":"134507924 FBXW9; (RefSeq) F-box\/WD repeat-containing protein 9\tK10265 FBXW9; F-box and WD-40 domain protein 9"
					},
					{
						"name":"134523282 F-box\/WD repeat-containing protein 10-like\tK10266 FBXW10; F-box and WD-40 domain protein 10"
					},
					{
						"name":"134508881 SKP2; (RefSeq) S-phase kinase-associated protein 2\tK03875 SKP2; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)"
					},
					{
						"name":"134510847 FBXL2; (RefSeq) F-box\/LRR-repeat protein 2\tK10268 FBXL2_20; F-box and leucine-rich repeat protein 2\/20"
					},
					{
						"name":"134524599 FBXL20; (RefSeq) F-box\/LRR-repeat protein 20 isoform X1\tK10268 FBXL2_20; F-box and leucine-rich repeat protein 2\/20"
					},
					{
						"name":"134516033 FBXL3; (RefSeq) F-box\/LRR-repeat protein 3\tK10269 FBXL3; F-box and leucine-rich repeat protein 3"
					},
					{
						"name":"134513359 FBXL4; (RefSeq) F-box\/LRR-repeat protein 4\tK10270 FBXL4; F-box and leucine-rich repeat protein 4"
					},
					{
						"name":"134516273 FBXL5; (RefSeq) F-box\/LRR-repeat protein 5 isoform X1\tK10271 FBXL5; F-box and leucine-rich repeat protein 5"
					},
					{
						"name":"134511723 FBXL7; (RefSeq) F-box\/LRR-repeat protein 7 isoform X1\tK10273 FBXL7; F-box and leucine-rich repeat protein 7"
					},
					{
						"name":"134515357 FBXL8; (RefSeq) F-box\/LRR-repeat protein 8\tK10274 FBXL8; F-box and leucine-rich repeat protein 8"
					},
					{
						"name":"134514171 KDM2A; (RefSeq) lysine-specific demethylase 2A isoform X1\tK10276 FBXL10_11; F-box and leucine-rich repeat protein 10\/11 [EC:1.14.11.27]"
					},
					{
						"name":"134523018 KDM2B; (RefSeq) lysine-specific demethylase 2B isoform X1\tK10276 FBXL10_11; F-box and leucine-rich repeat protein 10\/11 [EC:1.14.11.27]"
					},
					{
						"name":"134512092 FBXL13; (RefSeq) LOW QUALITY PROTEIN: F-box and leucine-rich repeat protein 13\tK10279 FBXL13; dynein regulatory complex subunit 6"
					},
					{
						"name":"134507715 FBXL14; (RefSeq) F-box\/LRR-repeat protein 14\tK10280 FBXL14; F-box and leucine-rich repeat protein 14"
					},
					{
						"name":"134517257 FBXL15; (RefSeq) F-box\/LRR-repeat protein 15\tK10281 FBXL15; F-box and leucine-rich repeat protein 15"
					},
					{
						"name":"134520023 FBXL16; (RefSeq) F-box\/LRR-repeat protein 16\tK10282 FBXL16; F-box and leucine-rich repeat protein 16"
					},
					{
						"name":"134508612 FBXL17; (RefSeq) F-box\/LRR-repeat protein 17\tK10283 FBXL17; F-box and leucine-rich repeat protein 17"
					},
					{
						"name":"134519744 FBXL18; (RefSeq) F-box\/LRR-repeat protein 18 isoform X1\tK10284 FBXL18; F-box and leucine-rich repeat protein 18"
					},
					{
						"name":"134509249 LOW QUALITY PROTEIN: F-box\/LRR-repeat protein 19-like\tK10285 FBXL19; F-box and leucine-rich repeat protein 19"
					},
					{
						"name":"134521931 LOW QUALITY PROTEIN: F-box\/LRR-repeat protein 21-like\tK10287 FBXL21; F-box and leucine-rich repeat protein 21"
					},
					{
						"name":"134520449 FBXL22; (RefSeq) F-box and leucine-rich protein 22\tK10288 FBXL22; F-box and leucine-rich repeat protein 22"
					},
					{
						"name":"134519265 CCNF; (RefSeq) cyclin-F isoform X1\tK10289 CCNF; F-box protein 1 (cyclin F)"
					},
					{
						"name":"134524018 FBXO2; (RefSeq) F-box only protein 2 isoform X1\tK10099 FBXO2; F-box protein 2"
					},
					{
						"name":"134514269 FBXO3; (RefSeq) F-box only protein 3\tK10290 FBXO3; F-box protein 3"
					},
					{
						"name":"134508631 FBXO4; (RefSeq) F-box only protein 4 isoform X1\tK10291 FBXO4; F-box protein 4"
					},
					{
						"name":"134513146 FBXO5; (RefSeq) F-box only protein 5 isoform X1\tK10292 FBXO5; F-box protein 5"
					},
					{
						"name":"134524017 FBXO6; (RefSeq) F-box only protein 6\tK10100 FBXO6; F-box protein 6"
					},
					{
						"name":"134509062 FBXO7; (RefSeq) F-box only protein 7\tK10293 FBXO7; F-box protein 7"
					},
					{
						"name":"134515903 FBXO8; (RefSeq) F-box only protein 8\tK10294 FBXO8; F-box protein 8"
					},
					{
						"name":"134513497 FBXO9; (RefSeq) F-box only protein 9 isoform X1\tK10295 FBXO9; F-box protein 9"
					},
					{
						"name":"134509007 FBXO10; (RefSeq) F-box only protein 10 isoform X1\tK10296 FBXO10; F-box protein 10"
					},
					{
						"name":"134512613 FBXO11; (RefSeq) F-box only protein 11 isoform X1\tK10297 FBXO11; F-box protein 11"
					},
					{
						"name":"134510741 FBXO15; (RefSeq) F-box only protein 15\tK10298 FBXO15; F-box protein 15"
					},
					{
						"name":"134513673 FBXO16; (RefSeq) F-box only protein 16\tK10299 FBXO16; F-box protein 16"
					},
					{
						"name":"134510428 FBH1; (RefSeq) F-box DNA helicase 1 isoform X1\tK10300 FBH1; F-box DNA helicase 1 [EC:5.6.2.4]"
					},
					{
						"name":"134515975 LMO7; (RefSeq) LIM domain only protein 7 isoform X1\tK06084 LMO7; F-box protein 20"
					},
					{
						"name":"134522716 FBXO21; (RefSeq) F-box only protein 21 isoform X1\tK10301 FBXO21; F-box protein 21"
					},
					{
						"name":"134521187 FBXO22; (RefSeq) F-box only protein 22\tK10302 FBXO22; F-box protein 22"
					},
					{
						"name":"134512239 FBXO32; (RefSeq) F-box only protein 32\tK10305 FBXO25_32; F-box protein 25\/32"
					},
					{
						"name":"134513518 FBXO25; (RefSeq) F-box only protein 25 isoform X1\tK10305 FBXO25_32; F-box protein 25\/32"
					},
					{
						"name":"134512658 FBXO28; (RefSeq) F-box only protein 28\tK10306 FBXO28; F-box protein 28"
					},
					{
						"name":"134513111 FBXO30; (RefSeq) F-box only protein 30\tK10307 FBXO30; F-box protein 30"
					},
					{
						"name":"134515622 FBXO31; (RefSeq) F-box only protein 31 isoform X1\tK10308 FBXO31; F-box protein 31"
					},
					{
						"name":"134515205 FBXO33; (RefSeq) F-box only protein 33\tK10310 FBXO33; F-box protein 33"
					},
					{
						"name":"134514500 FBXO34; (RefSeq) F-box only protein 34\tK10311 FBXO34; F-box protein 34"
					},
					{
						"name":"134517083 FBXO36; (RefSeq) F-box only protein 36\tK10312 FBXO36; F-box protein 36"
					},
					{
						"name":"134521772 FBXO38; (RefSeq) F-box only protein 38 isoform X1\tK10313 FBXO38; F-box protein 38"
					},
					{
						"name":"134518165 FBXO39; (RefSeq) F-box only protein 39 isoform X1\tK10314 FBXO39; F-box protein 39"
					},
					{
						"name":"134523724 FBXO40; (RefSeq) F-box only protein 40\tK10315 FBXO40; F-box protein 40"
					},
					{
						"name":"134516280 FBXO41; (RefSeq) F-box only protein 41 isoform X1\tK10316 FBXO41; F-box protein 41"
					},
					{
						"name":"134524171 FBXO42; (RefSeq) F-box only protein 42\tK10317 FBXO42; F-box protein 42"
					},
					{
						"name":"134510812 FBXO43; (RefSeq) F-box only protein 43\tK10318 FBXO43; F-box protein 43"
					},
					{
						"name":"134517622 FBXO45; (RefSeq) F-box\/SPRY domain-containing protein 1\tK10319 FBXO45; F-box protein 45"
					},
					{
						"name":"134509373 FBXO46; (RefSeq) F-box only protein 46\tK10320 FBXO46; F-box protein 46"
					},
					{
						"name":"134524481 FBXO47; (RefSeq) F-box only protein 47\tK10321 FBXO47; F-box protein 47"
					}
					]
				}
				]
			},
			{
				"name":"Cul2 complex",
				"children":[
				{
					"name":"Ring finger protein",
					"children":[
					{
						"name":"134509872 RBX1; (RefSeq) E3 ubiquitin-protein ligase RBX1\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
					}
					]
				},
				{
					"name":"Cullin",
					"children":[
					{
						"name":"134511089 CUL2; (RefSeq) cullin-2 isoform X1\tK03870 CUL2; cullin 2"
					}
					]
				},
				{
					"name":"Adoptor protein",
					"children":[
					{
						"name":"134512056 ELOC; (RefSeq) elongin-C\tK03872 ELOC; elongin-C"
					},
					{
						"name":"134517840 ELOB; (RefSeq) elongin-B\tK03873 ELOB; elongin-B"
					}
					]
				},
				{
					"name":"Target recognizing subunit",
					"children":[
					{
						"name":"134521452 VHL; (RefSeq) von Hippel-Lindau disease tumor suppressor\tK03871 VHL; von Hippel-Lindau disease tumor supressor"
					},
					{
						"name":"134515217 LRR1; (RefSeq) leucine-rich repeat protein 1\tK10348 LRR1; LRR-repeat protein 1"
					},
					{
						"name":"134508404 FEM1C; (RefSeq) protein fem-1 homolog C\tK25805 FEM1A_C; protein fem-1 homolog A\/C"
					},
					{
						"name":"134526322 FEM1A; (RefSeq) protein fem-1 homolog A\tK25805 FEM1A_C; protein fem-1 homolog A\/C"
					},
					{
						"name":"134520496 FEM1B; (RefSeq) protein fem-1 homolog B\tK10349 FEM1B; protein fem-1 homolog B"
					},
					{
						"name":"134518080 APPBP2; (RefSeq) amyloid protein-binding protein 2\tK25806 APPBP2; amyloid protein-binding protein 2"
					},
					{
						"name":"134515141 KLHDC2; (RefSeq) kelch domain-containing protein 2\tK25807 KLHDC2; kelch domain-containing protein 2"
					},
					{
						"name":"134512558 KLHDC3; (RefSeq) kelch domain-containing protein 3\tK25808 KLHDC3; kelch domain-containing protein 3"
					},
					{
						"name":"134510440 KLHDC10; (RefSeq) kelch domain-containing protein 10\tK25809 KLHDC10; kelch domain-containing protein 10"
					},
					{
						"name":"134519188 protein zyg-11 homolog B isoform X1\tK10350 ZYG11; Zyg-11 protein"
					},
					{
						"name":"134523940 ZER1; (RefSeq) protein zer-1 homolog\tK10350 ZYG11; Zyg-11 protein"
					},
					{
						"name":"134516990 ZSWIM8; (RefSeq) zinc finger SWIM domain-containing protein 8 isoform X1\tK25207 ZSWIM8; zinc finger SWIM domain-containing protein 8"
					}
					]
				}
				]
			},
			{
				"name":"Cul3 complex",
				"children":[
				{
					"name":"Ring finger protein",
					"children":[
					{
						"name":"134509872 RBX1; (RefSeq) E3 ubiquitin-protein ligase RBX1\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
					}
					]
				},
				{
					"name":"Cullin",
					"children":[
					{
						"name":"134517313 CUL3; (RefSeq) cullin-3\tK03869 CUL3; cullin 3"
					}
					]
				},
				{
					"name":"Adoptor and target recognizing subunit (BTB)",
					"children":[
					{
						"name":"134515869 KLHL1; (RefSeq) kelch-like protein 1\tK10442 KLHL1_4_5; kelch-like protein 1\/4\/5"
					},
					{
						"name":"134516059 KLHL5; (RefSeq) kelch-like protein 5 isoform X1\tK10442 KLHL1_4_5; kelch-like protein 1\/4\/5"
					},
					{
						"name":"134520827 KLHL4; (RefSeq) kelch-like protein 4\tK10442 KLHL1_4_5; kelch-like protein 1\/4\/5"
					},
					{
						"name":"134516186 KLHL2; (RefSeq) kelch-like protein 2 isoform X1\tK10443 KLHL2_3; kelch-like protein 2\/3"
					},
					{
						"name":"134522176 KLHL3; (RefSeq) kelch-like protein 3 isoform X1\tK10443 KLHL2_3; kelch-like protein 2\/3"
					},
					{
						"name":"134517684 KLHL6; (RefSeq) kelch-like protein 6\tK10444 KLHL6; kelch-like protein 6"
					},
					{
						"name":"134511290 KLHL7; (RefSeq) kelch-like protein 7 isoform X1\tK10445 KLHL7; kelch-like protein 7"
					},
					{
						"name":"134515806 KLHL8; (RefSeq) kelch-like protein 8\tK10446 KLHL8; kelch-like protein 8"
					},
					{
						"name":"134520505 KLHL13; (RefSeq) kelch-like protein 13 isoform X1\tK10447 KLHL9_13; kelch-like protein 9\/13"
					},
					{
						"name":"134523598 kelch-like protein 9\tK10447 KLHL9_13; kelch-like protein 9\/13"
					},
					{
						"name":"134516312 kelch-like protein 10\tK10448 KLHL10; kelch-like protein 10"
					},
					{
						"name":"134524657 KLHL10; (RefSeq) kelch-like protein 10\tK10448 KLHL10; kelch-like protein 10"
					},
					{
						"name":"134524626 KLHL11; (RefSeq) kelch-like protein 11\tK10449 KLHL11; kelch-like protein 11"
					},
					{
						"name":"134525440 KLHL12; (RefSeq) LOW QUALITY PROTEIN: kelch-like protein 12\tK10450 KLHL12; kelch-like protein 12"
					},
					{
						"name":"134511957 KLHL14; (RefSeq) kelch-like protein 14\tK10451 KLHL14; kelch-like protein 14"
					},
					{
						"name":"134519279 KLHL15; (RefSeq) kelch-like protein 15\tK10452 KLHL15; kelch-like protein 15"
					},
					{
						"name":"134514578 GAN; (RefSeq) gigaxonin\tK10453 KLHL16; kelch-like protein 16 (gigaxonin)"
					},
					{
						"name":"134524176 KLHL17; (RefSeq) kelch-like protein 17 isoform X1\tK10454 KLHL17; kelch-like protein 17 (actinfilin)"
					},
					{
						"name":"134510967 KLHL18; (RefSeq) kelch-like protein 18 isoform X1\tK10455 KLHL18; kelch-like protein 18"
					},
					{
						"name":"134519646 KLHL20; (RefSeq) kelch-like protein 20 isoform X1\tK10457 KLHL20; kelch-like protein 20"
					},
					{
						"name":"134524247 KLHL21; (RefSeq) kelch-like protein 21\tK10458 KLHL21; kelch-like protein 21"
					},
					{
						"name":"134522676 KLHL22; (RefSeq) kelch-like protein 22\tK10459 KLHL22; kelch-like protein 22"
					},
					{
						"name":"134518087 KLHL23; (RefSeq) kelch-like protein 23\tK10460 KLHL23; kelch-like protein 23"
					},
					{
						"name":"134512140 KLHL35; (RefSeq) kelch-like protein 35\tK10461 KLHL24_35; kelch-like protein 24\/35"
					},
					{
						"name":"134517982 KLHL24; (RefSeq) kelch-like protein 24\tK10461 KLHL24_35; kelch-like protein 24\/35"
					},
					{
						"name":"134508495 ENC1; (RefSeq) ectoderm-neural cortex protein 1\tK10462 KLHL25_37; kelch-like protein 25\/37 (ectoderm-neural cortex protein)"
					},
					{
						"name":"134520862 KLHL25; (RefSeq) kelch-like protein 25\tK10462 KLHL25_37; kelch-like protein 25\/37 (ectoderm-neural cortex protein)"
					},
					{
						"name":"134526146 PEX11G; (RefSeq) peroxisomal membrane protein 11C isoform X1\tK10462 KLHL25_37; kelch-like protein 25\/37 (ectoderm-neural cortex protein)"
					},
					{
						"name":"134526410 KLHL26; (RefSeq) kelch-like protein 26 isoform X1\tK10463 KLHL26; kelch-like protein 26"
					},
					{
						"name":"134520080 IPP; (RefSeq) actin-binding protein IPP\tK13956 IPP; actin-binding protein IPP"
					},
					{
						"name":"134515112 KLHL28; (RefSeq) kelch-like protein 28\tK10464 KLHL28; kelch-like protein 28"
					},
					{
						"name":"134513600 KLHL29; (RefSeq) kelch-like protein 29 isoform X1\tK10465 KLHL29; kelch-like protein 29"
					},
					{
						"name":"134517603 KLHL30; (RefSeq) kelch-like protein 30 isoform X1\tK10466 KLHL30; kelch-like protein 30"
					},
					{
						"name":"134513494 KLHL31; (RefSeq) kelch-like protein 31\tK10467 KLHL31; kelch-like protein 31"
					},
					{
						"name":"134525109 LOW QUALITY PROTEIN: kelch-like protein 31\tK10467 KLHL31; kelch-like protein 31"
					},
					{
						"name":"134513363 KLHL32; (RefSeq) kelch-like protein 32 isoform X1\tK10468 KLHL32; kelch-like protein 32"
					},
					{
						"name":"134526498 KLHL33; (RefSeq) kelch-like protein 33\tK13957 KLHL33; kelch-like protein 33"
					},
					{
						"name":"134519184 KLHL34; (RefSeq) kelch-like protein 34\tK10469 KLHL34; kelch-like protein 34"
					},
					{
						"name":"134515599 KLHL36; (RefSeq) kelch-like protein 36\tK13958 KLHL36; kelch-like protein 36"
					},
					{
						"name":"134512240 KLHL38; (RefSeq) kelch-like protein 38\tK13959 KLHL38; kelch-like protein 38"
					},
					{
						"name":"134509982 KLHL42; (RefSeq) kelch-like protein 42\tK27973 KLHL42; kelch-like protein 42"
					},
					{
						"name":"134511495 KBTBD2; (RefSeq) kelch repeat and BTB domain-containing protein 2\tK10470 KBTBD2; kelch repeat and BTB domain-containing protein 2"
					},
					{
						"name":"134513458 KBTBD3; (RefSeq) kelch repeat and BTB domain-containing protein 3 isoform X1\tK10471 KBTBD3; kelch repeat and BTB domain-containing protein 3"
					},
					{
						"name":"134514330 KBTBD4; (RefSeq) kelch repeat and BTB domain-containing protein 4 isoform X1\tK10472 KBTBD4; kelch repeat and BTB domain-containing protein 4"
					},
					{
						"name":"134511001 KLHL40; (RefSeq) kelch-like protein 40\tK10473 KBTBD5_10; kelch repeat and BTB domain-containing protein 5\/10"
					},
					{
						"name":"134518897 KLHL41; (RefSeq) kelch-like protein 41\tK10473 KBTBD5_10; kelch repeat and BTB domain-containing protein 5\/10"
					},
					{
						"name":"134521556 KBTBD8; (RefSeq) LOW QUALITY PROTEIN: kelch repeat and BTB domain-containing protein 8\tK10475 KBTBD8; kelch repeat and BTB domain-containing protein 8"
					},
					{
						"name":"134513511 KBTBD11; (RefSeq) kelch repeat and BTB domain-containing protein 11\tK10476 KBTBD11; kelch repeat and BTB domain-containing protein 11"
					},
					{
						"name":"134521634 KBTBD12; (RefSeq) kelch repeat and BTB domain-containing protein 12 isoform X1\tK21912 KBTBD12; kelch repeat and BTB domain-containing protein 12"
					},
					{
						"name":"134520951 KBTBD13; (RefSeq) kelch repeat and BTB domain-containing protein 13\tK21913 KBTBD13; kelch repeat and BTB domain-containing protein 13"
					},
					{
						"name":"134520385 BTBD1; (RefSeq) BTB\/POZ domain-containing protein 1\tK10477 BTBD1_2; BTB\/POZ domain-containing protein 1\/2"
					},
					{
						"name":"134526496 BTBD2; (RefSeq) BTB\/POZ domain-containing protein 2\tK10477 BTBD1_2; BTB\/POZ domain-containing protein 1\/2"
					},
					{
						"name":"134512443 BTBD3; (RefSeq) BTB\/POZ domain-containing protein 3 isoform X1\tK10478 BTBD3_6; BTB\/POZ domain-containing protein 3\/6"
					},
					{
						"name":"134515004 BTBD6; (RefSeq) BTB\/POZ domain-containing protein 6 isoform X1\tK10478 BTBD3_6; BTB\/POZ domain-containing protein 3\/6"
					},
					{
						"name":"134514600 BTBD7; (RefSeq) BTB\/POZ domain-containing protein 7 isoform X1\tK10479 BTBD7; BTB\/POZ domain-containing protein 7"
					},
					{
						"name":"134519250 BTBD8; (RefSeq) BTB\/POZ domain-containing protein 8\tK10480 BTBD8; BTB\/POZ domain-containing protein 8"
					},
					{
						"name":"134512873 BTBD9; (RefSeq) BTB\/POZ domain-containing protein 9\tK10481 BTBD9; BTB\/POZ domain-containing protein 9"
					},
					{
						"name":"134515594 BTBD10; (RefSeq) BTB\/POZ domain-containing protein 10 isoform X1\tK10482 BTBD10; BTB\/POZ domain-containing protein 10"
					},
					{
						"name":"134509014 ABTB3; (RefSeq) ankyrin repeat and BTB\/POZ domain-containing protein 3 isoform X1\tK10483 BTBD11; BTB\/POZ domain-containing protein 11"
					},
					{
						"name":"134519755 SLX4; (RefSeq) structure-specific endonuclease subunit SLX4 isoform X1\tK10484 BTBD12; structure-specific endonuclease subunit SLX4 (BTB\/POZ domain-containing protein 12)"
					},
					{
						"name":"134526731 GMCL1; (RefSeq) germ cell-less protein-like 1\tK10485 BTBD13; BTB\/POZ domain-containing protein 13 (germ cell-less protein-like 1)"
					},
					{
						"name":"134507923 NACC1; (RefSeq) LOW QUALITY PROTEIN: nucleus accumbens-associated protein 1\tK10486 BTBD14; BTB\/POZ domain-containing protein 14"
					},
					{
						"name":"134523682 NACC2; (RefSeq) nucleus accumbens-associated protein 2\tK10486 BTBD14; BTB\/POZ domain-containing protein 14"
					},
					{
						"name":"134515011 ZBTB1; (RefSeq) zinc finger and BTB domain-containing protein 1 isoform X1\tK10488 ZBTB1; zinc finger and BTB domain-containing protein 1"
					},
					{
						"name":"134513136 ZBTB2; (RefSeq) zinc finger and BTB domain-containing protein 2 isoform X1\tK10489 ZBTB2; zinc finger and BTB domain-containing protein 2"
					},
					{
						"name":"134508093 ZBTB3; (RefSeq) LOW QUALITY PROTEIN: zinc finger and BTB domain-containing protein 3\tK10490 ZBTB3; zinc finger and BTB domain-containing protein 3"
					},
					{
						"name":"134509490 zinc finger and BTB domain-containing protein 4-like\tK10491 ZBTB4; zinc finger and BTB domain-containing protein 4"
					},
					{
						"name":"134508177 ZBTB5; (RefSeq) zinc finger and BTB domain-containing protein 5\tK10492 ZBTB5; zinc finger and BTB domain-containing protein 5"
					},
					{
						"name":"134523882 ZBTB6; (RefSeq) zinc finger and BTB domain-containing protein 6\tK10493 ZBTB6; zinc finger and BTB domain-containing protein 6"
					},
					{
						"name":"134508892 ZBTB7C; (RefSeq) zinc finger and BTB domain-containing protein 7C\tK10494 ZBTB7; zinc finger and BTB domain-containing protein 7"
					},
					{
						"name":"134525922 ZBTB7B; (RefSeq) zinc finger and BTB domain-containing protein 7B isoform X1\tK10494 ZBTB7; zinc finger and BTB domain-containing protein 7"
					},
					{
						"name":"134526308 ZBTB7A; (RefSeq) zinc finger and BTB domain-containing protein 7A isoform X1\tK10494 ZBTB7; zinc finger and BTB domain-containing protein 7"
					},
					{
						"name":"134525174 ZBTB8A; (RefSeq) zinc finger and BTB domain-containing protein 8A isoform X1\tK10495 ZBTB8; zinc finger and BTB domain-containing protein 8"
					},
					{
						"name":"134525176 ZBTB8B; (RefSeq) zinc finger and BTB domain-containing protein 8B isoform X1\tK10495 ZBTB8; zinc finger and BTB domain-containing protein 8"
					},
					{
						"name":"134507807 zinc finger and BTB domain-containing protein 9-like isoform X1\tK10496 ZBTB9; zinc finger and BTB domain-containing protein 9"
					},
					{
						"name":"134509563 LOW QUALITY PROTEIN: zinc finger and BTB domain-containing protein 9-like\tK10496 ZBTB9; zinc finger and BTB domain-containing protein 9"
					},
					{
						"name":"134512075 ZBTB10; (RefSeq) zinc finger and BTB domain-containing protein 10\tK10497 ZBTB10; zinc finger and BTB domain-containing protein 10"
					},
					{
						"name":"134522316 ZBTB11; (RefSeq) zinc finger and BTB domain-containing protein 11\tK10498 ZBTB11; zinc finger and BTB domain-containing protein 11"
					},
					{
						"name":"134525084 ZBTB16; (RefSeq) zinc finger and BTB domain-containing protein 16\tK10055 ZBTB16; zinc finger and BTB domain-containing protein 16"
					},
					{
						"name":"134524193 ZBTB17; (RefSeq) zinc finger and BTB domain-containing protein 17 isoform X1\tK10500 ZBTB17; zinc finger and BTB domain-containing protein 17"
					},
					{
						"name":"134522965 ZBTB20; (RefSeq) zinc finger and BTB domain-containing protein 20\tK10501 ZBTB20; zinc finger and BTB domain-containing protein 20"
					},
					{
						"name":"134513316 ZBTB24; (RefSeq) zinc finger and BTB domain-containing protein 24\tK10503 ZBTB24; zinc finger and BTB domain-containing protein 24"
					},
					{
						"name":"134515012 ZBTB25; (RefSeq) zinc finger and BTB domain-containing protein 25 isoform X1\tK10504 ZBTB25; zinc finger and BTB domain-containing protein 25"
					},
					{
						"name":"134523881 ZBTB26; (RefSeq) zinc finger and BTB domain-containing protein 26\tK10505 ZBTB26; zinc finger and BTB domain-containing protein 26"
					},
					{
						"name":"134521003 ZBTB33; (RefSeq) transcriptional regulator Kaiso isoform X1\tK10507 ZBTB33; zinc finger and BTB domain-containing protein 33"
					},
					{
						"name":"134523929 ZBTB34; (RefSeq) zinc finger and BTB domain-containing protein 34 isoform X1\tK10508 ZBTB34; zinc finger and BTB domain-containing protein 34"
					},
					{
						"name":"134519472 ZBTB37; (RefSeq) zinc finger and BTB domain-containing protein 37\tK10509 ZBTB37; zinc finger and BTB domain-containing protein 37"
					},
					{
						"name":"134517091 ZBTB38; (RefSeq) zinc finger and BTB domain-containing protein 38\tK10510 ZBTB38; zinc finger and BTB domain-containing protein 38"
					},
					{
						"name":"134526865 ZBTB39; (RefSeq) zinc finger and BTB domain-containing protein 39\tK10511 ZBTB39; zinc finger and BTB domain-containing protein 39"
					},
					{
						"name":"134524048 ZBTB40; (RefSeq) zinc finger and BTB domain-containing protein 40 isoform X1\tK10512 ZBTB40; zinc finger and BTB domain-containing protein 40"
					},
					{
						"name":"134519697 ZBTB41; (RefSeq) zinc finger and BTB domain-containing protein 41\tK10513 ZBTB41; zinc finger and BTB domain-containing protein 41"
					},
					{
						"name":"134523930 ZBTB43; (RefSeq) zinc finger and BTB domain-containing protein 43\tK10514 ZBTB43; zinc finger and BTB domain-containing protein 43"
					},
					{
						"name":"134524872 ZBTB44; (RefSeq) zinc finger and BTB domain-containing protein 44 isoform X1\tK10515 ZBTB44; zinc finger and BTB domain-containing protein 44"
					},
					{
						"name":"134507741 ZBTB45; (RefSeq) zinc finger and BTB domain-containing protein 45\tK10516 ZBTB45; zinc finger and BTB domain-containing protein 45"
					},
					{
						"name":"134522241 ZBTB46; (RefSeq) zinc finger and BTB domain-containing protein 46 isoform X1\tK10517 ZBTB46; zinc finger and BTB domain-containing protein 46"
					},
					{
						"name":"134511000 ZBTB47; (RefSeq) zinc finger and BTB domain-containing protein 47 isoform X1\tK10518 ZBTB47; zinc finger and BTB domain-containing protein 47"
					},
					{
						"name":"134524246 ZBTB48; (RefSeq) telomere zinc finger-associated protein\tK10519 ZBTB48; zinc finger and BTB domain-containing protein 48"
					},
					{
						"name":"134521352 ABTB1; (RefSeq) ankyrin repeat and BTB\/POZ domain-containing protein 1\tK10520 ABTB1; ankyrin repeat and BTB\/POZ domain-containing protein 1"
					},
					{
						"name":"134515491 ABTB2; (RefSeq) ankyrin repeat and BTB\/POZ domain-containing protein 2 isoform X1\tK10521 ABTB2; ankyrin repeat and BTB\/POZ domain-containing protein 2"
					},
					{
						"name":"134516352 rho-related BTB domain-containing protein 2-like isoform X1\tK07868 RHOBTB1_2; Rho-related BTB domain-containing protein 1\/2"
					},
					{
						"name":"134517746 RHOBTB1; (RefSeq) rho-related BTB domain-containing protein 1\tK07868 RHOBTB1_2; Rho-related BTB domain-containing protein 1\/2"
					},
					{
						"name":"134526552 RHOBTB2; (RefSeq) rho-related BTB domain-containing protein 2 isoform X1\tK07868 RHOBTB1_2; Rho-related BTB domain-containing protein 1\/2"
					},
					{
						"name":"134508430 RHOBTB3; (RefSeq) rho-related BTB domain-containing protein 3 isoform X1\tK07869 RHOBTB3; Rho-related BTB domain-containing protein 3"
					},
					{
						"name":"134518297 TNFAIP1; (RefSeq) BTB\/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2\tK15074 BACURD; BTB\/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein"
					},
					{
						"name":"134522826 KCTD10; (RefSeq) BTB\/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 isoform X1\tK15074 BACURD; BTB\/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein"
					},
					{
						"name":"134511943 KCTD1; (RefSeq) BTB\/POZ domain-containing protein KCTD1 isoform X1\tK21754 KCTD1_15; BTB\/POZ domain-containing protein KCTD1\/15"
					},
					{
						"name":"134515520 KCTD15; (RefSeq) BTB\/POZ domain-containing protein KCTD15 isoform X1\tK21754 KCTD1_15; BTB\/POZ domain-containing protein KCTD1\/15"
					},
					{
						"name":"134509478 KCTD17; (RefSeq) BTB\/POZ domain-containing protein KCTD17 isoform X1\tK21914 KCTD2_5_17; BTB\/POZ domain-containing protein KCTD2\/5\/17"
					},
					{
						"name":"134519496 KCTD5; (RefSeq) BTB\/POZ domain-containing protein KCTD5 isoform X1\tK21914 KCTD2_5_17; BTB\/POZ domain-containing protein KCTD2\/5\/17"
					},
					{
						"name":"134523284 KCTD2; (RefSeq) BTB\/POZ domain-containing protein KCTD2\tK21914 KCTD2_5_17; BTB\/POZ domain-containing protein KCTD2\/5\/17"
					},
					{
						"name":"134512762 KCTD3; (RefSeq) BTB\/POZ domain-containing protein KCTD3\tK21915 KCTD3; BTB\/POZ domain-containing protein KCTD3"
					},
					{
						"name":"134521621 KCTD6; (RefSeq) BTB\/POZ domain-containing protein KCTD6\tK21916 KCTD6; BTB\/POZ domain-containing protein KCTD6"
					},
					{
						"name":"134513243 KCTD14; (RefSeq) BTB\/POZ domain-containing protein KCTD14 isoform X1\tK21917 KCTD7_14; BTB\/POZ domain-containing protein KCTD7\/14"
					},
					{
						"name":"134518893 KCTD7; (RefSeq) BTB\/POZ domain-containing protein KCTD7\tK21917 KCTD7_14; BTB\/POZ domain-containing protein KCTD7\/14"
					},
					{
						"name":"134516016 KCTD12; (RefSeq) BTB\/POZ domain-containing protein KCTD12\tK21918 KCTD8_12_16; BTB\/POZ domain-containing protein KCTD8\/12\/16"
					},
					{
						"name":"134516635 KCTD8; (RefSeq) BTB\/POZ domain-containing protein KCTD8\tK21918 KCTD8_12_16; BTB\/POZ domain-containing protein KCTD8\/12\/16"
					},
					{
						"name":"134520750 BTB\/POZ domain-containing protein KCTD12-like\tK21918 KCTD8_12_16; BTB\/POZ domain-containing protein KCTD8\/12\/16"
					},
					{
						"name":"134521778 KCTD16; (RefSeq) BTB\/POZ domain-containing protein KCTD16\tK21918 KCTD8_12_16; BTB\/POZ domain-containing protein KCTD8\/12\/16"
					},
					{
						"name":"134526604 KCTD9; (RefSeq) BTB\/POZ domain-containing protein KCTD9 isoform X1\tK21919 KCTD9; BTB\/POZ domain-containing protein KCTD9"
					},
					{
						"name":"134518985 KCTD18; (RefSeq) BTB\/POZ domain-containing protein KCTD18\tK21921 KCTD18; BTB\/POZ domain-containing protein KCTD18"
					},
					{
						"name":"134511866 KCTD21; (RefSeq) BTB\/POZ domain-containing protein KCTD21\tK21922 KCTD21; BTB\/POZ domain-containing protein KCTD21"
					},
					{
						"name":"134522923 DIABLO; (RefSeq) diablo IAP-binding mitochondrial protein\tK10522 DIABLO; diablo"
					},
					{
						"name":"134518612 SPOPL; (RefSeq) speckle-type POZ protein-like\tK10523 SPOP; speckle-type POZ protein"
					},
					{
						"name":"134524621 SPOP; (RefSeq) speckle-type POZ protein\tK10523 SPOP; speckle-type POZ protein"
					},
					{
						"name":"134525456 LZTR1; (RefSeq) leucine-zipper-like transcriptional regulator 1\tK23330 LZTR1; leucine-zipper-like transcriptional regulator 1"
					}
					]
				}
				]
			},
			{
				"name":"Cul4 complex",
				"children":[
				{
					"name":"Ring finger protein",
					"children":[
					{
						"name":"134509872 RBX1; (RefSeq) E3 ubiquitin-protein ligase RBX1\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
					}
					]
				},
				{
					"name":"Cullin",
					"children":[
					{
						"name":"134517068 CUL4A; (RefSeq) cullin-4A\tK10609 CUL4; cullin 4"
					},
					{
						"name":"134521192 CUL4B; (RefSeq) cullin-4B\tK10609 CUL4; cullin 4"
					}
					]
				},
				{
					"name":"Adoptor protein",
					"children":[
					{
						"name":"134514944 DDB1; (RefSeq) DNA damage-binding protein 1\tK10610 DDB1; DNA damage-binding protein 1"
					}
					]
				},
				{
					"name":"Target recognizing subunit (DCAF)",
					"children":[
					{
						"name":"134514309 DDB2; (RefSeq) DNA damage-binding protein 2 isoform X1\tK10140 DDB2; DNA damage-binding protein 2"
					},
					{
						"name":"134509053 ERCC8; (RefSeq) DNA excision repair protein ERCC-8 isoform X1\tK10570 ERCC8; DNA excision repair protein ERCC-8"
					},
					{
						"name":"134520944 DET1; (RefSeq) DET1 homolog\tK10571 DET1; de-etiolated-1"
					},
					{
						"name":"134519238 COP1; (RefSeq) E3 ubiquitin-protein ligase COP1 isoform X1\tK10143 RFWD2; E3 ubiquitin-protein ligase RFWD2 [EC:2.3.2.27]"
					},
					{
						"name":"134526306 DDA1; (RefSeq) DET1- and DDB1-associated protein 1\tK11792 DDA1; DET1- and DDB1-associated protein 1"
					},
					{
						"name":"134521474 CRBN; (RefSeq) protein cereblon isoform X1\tK11793 CRBN; cereblon"
					},
					{
						"name":"134522514 TRPC4AP; (RefSeq) short transient receptor potential channel 4-associated protein\tK11796 TRPC4AP; Trpc4-associated protein"
					},
					{
						"name":"134521409 DCAF1; (RefSeq) DDB1- and CUL4-associated factor 1 isoform X1\tK11789 DCAF1; DDB1- and CUL4-associated factor 1 [EC:2.7.11.1]"
					},
					{
						"name":"134513801 DTL; (RefSeq) denticleless protein homolog\tK11790 DTL; denticleless"
					},
					{
						"name":"134514651 DCAF4; (RefSeq) DDB1- and CUL4-associated factor 4\tK11799 DCAF4; DDB1- and CUL4-associated factor 4"
					},
					{
						"name":"134514068 DCAF5; (RefSeq) DDB1- and CUL4-associated factor 5 isoform X1\tK11800 DCAF5; DDB1- and CUL4-associated factor 5"
					},
					{
						"name":"134521749 DCAF6; (RefSeq) DDB1- and CUL4-associated factor 6 isoform X1\tK11795 DCAF6; DDB1- and CUL4-associated factor 6"
					},
					{
						"name":"134524460 DCAF7; (RefSeq) DDB1- and CUL4-associated factor 7\tK11805 DCAF7; DDB1- and CUL4-associated factor 7"
					},
					{
						"name":"134526061 DCAF8; (RefSeq) DDB1- and CUL4-associated factor 8 isoform X1\tK11804 DCAF8; DDB1- and CUL4-associated factor 8"
					},
					{
						"name":"134508772 DCAF10; (RefSeq) DDB1- and CUL4-associated factor 10\tK11802 DCAF10; DDB1- and CUL4-associated factor 10"
					},
					{
						"name":"134509809 DCAF11; (RefSeq) LOW QUALITY PROTEIN: DDB1- and CUL4-associated factor 11\tK11801 DCAF11; DDB1- and CUL4-associated factor 11"
					},
					{
						"name":"134508269 DCAF12; (RefSeq) DDB1- and CUL4-associated factor 12\tK11803 DCAF12; DDB1- and CUL4-associated factor 12"
					},
					{
						"name":"134512184 DCAF13; (RefSeq) DDB1- and CUL4-associated factor 13\tK11806 DCAF13; DDB1- and CUL4-associated factor 13"
					},
					{
						"name":"134513435 PHIP; (RefSeq) PH-interacting protein isoform X1\tK11797 PHIP; PH-interacting protein"
					},
					{
						"name":"134518412 DCAF17; (RefSeq) DDB1- and CUL4-associated factor 17 isoform X1\tK23331 DCAF17; DDB1- and CUL4-associated factor 17"
					},
					{
						"name":"134520266 BRWD1; (RefSeq) bromodomain and WD repeat-containing protein 1 isoform X1\tK11798 BRWD1_3; bromodomain and WD repeat domain containing protein 1\/3"
					},
					{
						"name":"134521119 BRWD3; (RefSeq) bromodomain and WD repeat-containing protein 3 isoform X1\tK11798 BRWD1_3; bromodomain and WD repeat domain containing protein 1\/3"
					},
					{
						"name":"134512655 WDR26; (RefSeq) WD repeat-containing protein 26 isoform X1\tK22382 WDR26; WD repeat-containing protein 26"
					},
					{
						"name":"134508843 WDR70; (RefSeq) WD repeat-containing protein 70\tK24752 WDR70; WD repeat-containing protein 70"
					},
					{
						"name":"134520940 WDR76; (RefSeq) WD repeat-containing protein 76 isoform X1\tK24755 WDR76; WD repeat-containing protein 76"
					}
					]
				}
				]
			},
			{
				"name":"Cul5 complex",
				"children":[
				{
					"name":"Ring finger protein",
					"children":[
					{
						"name":"134517146 RNF7; (RefSeq) RING-box protein 2 isoform X1\tK10611 RBX2; RING-box protein 2"
					}
					]
				},
				{
					"name":"Cullin",
					"children":[
					{
						"name":"134513527 CUL5; (RefSeq) cullin-5\tK10612 CUL5; cullin 5"
					}
					]
				},
				{
					"name":"Adoptor protein",
					"children":[
					{
						"name":"134512056 ELOC; (RefSeq) elongin-C\tK03872 ELOC; elongin-C"
					},
					{
						"name":"134517840 ELOB; (RefSeq) elongin-B\tK03873 ELOB; elongin-B"
					}
					]
				},
				{
					"name":"Target recognizing subunit",
					"children":[
					{
						"name":"134521461 CISH; (RefSeq) cytokine-inducible SH2-containing protein\tK04701 CISH; cytokine inducible SH2-containing protein"
					},
					{
						"name":"134519579 SOCS1; (RefSeq) suppressor of cytokine signaling 1\tK04694 SOCS1; suppressor of cytokine signaling 1"
					},
					{
						"name":"134510028 SOCS2; (RefSeq) suppressor of cytokine signaling 2\tK04695 SOCS2; suppressor of cytokine signaling 2"
					},
					{
						"name":"134523193 SOCS3; (RefSeq) suppressor of cytokine signaling 3\tK04696 SOCS3; suppressor of cytokine signaling 3"
					},
					{
						"name":"134514825 SOCS4; (RefSeq) suppressor of cytokine signaling 4 isoform X1\tK04697 SOCS4; suppressor of cytokine signaling 4"
					},
					{
						"name":"134512843 SOCS5; (RefSeq) suppressor of cytokine signaling 5\tK04698 SOCS5; suppressor of cytokine signaling 5"
					},
					{
						"name":"134511842 SOCS6; (RefSeq) suppressor of cytokine signaling 6\tK04699 SOCS6_7; suppressor of cytokine signaling 6\/7"
					},
					{
						"name":"134524343 SOCS7; (RefSeq) suppressor of cytokine signaling 7 isoform X1\tK04699 SOCS6_7; suppressor of cytokine signaling 6\/7"
					},
					{
						"name":"134518597 ASB1; (RefSeq) ankyrin repeat and SOCS box protein 1 isoform X1\tK10323 ASB1; ankyrin repeat and SOCS box protein 1"
					},
					{
						"name":"134514627 ASB2; (RefSeq) ankyrin repeat and SOCS box protein 2 isoform X1\tK10324 ASB2; ankyrin repeat and SOCS box protein 2"
					},
					{
						"name":"134512509 ASB3; (RefSeq) ankyrin repeat and SOCS box protein 3 isoform X1\tK10325 ASB3; ankyrin repeat and SOCS box protein 3"
					},
					{
						"name":"134511232 ASB4; (RefSeq) ankyrin repeat and SOCS box protein 4\tK10326 ASB4; ankyrin repeat and SOCS box protein 4"
					},
					{
						"name":"134516682 ASB5; (RefSeq) ankyrin repeat and SOCS box protein 5 isoform X1\tK10327 ASB5; ankyrin repeat and SOCS box protein 5"
					},
					{
						"name":"134523799 ASB6; (RefSeq) ankyrin repeat and SOCS box protein 6\tK10328 ASB6; ankyrin repeat and SOCS box protein 6"
					},
					{
						"name":"134520961 ASB7; (RefSeq) ankyrin repeat and SOCS box protein 7\tK10329 ASB7; ankyrin repeat and SOCS box protein 7"
					},
					{
						"name":"134526855 ASB8; (RefSeq) ankyrin repeat and SOCS box protein 8\tK10330 ASB8; ankyrin repeat and SOCS box protein 8"
					},
					{
						"name":"134518861 ASB9; (RefSeq) ankyrin repeat and SOCS box protein 9\tK10331 ASB9; ankyrin repeat and SOCS box protein 9"
					},
					{
						"name":"134510928 ASB10; (RefSeq) ankyrin repeat and SOCS box protein 10 isoform X1\tK10332 ASB10; ankyrin repeat and SOCS box protein 10"
					},
					{
						"name":"134518868 ASB11; (RefSeq) ankyrin repeat and SOCS box protein 11\tK10333 ASB11; ankyrin repeat and SOCS box protein 11"
					},
					{
						"name":"134520741 ankyrin repeat and SOCS box protein 12-like\tK10334 ASB12; ankyrin repeat and SOCS box protein 12"
					},
					{
						"name":"134520777 ankyrin repeat and SOCS box protein 12-like\tK10334 ASB12; ankyrin repeat and SOCS box protein 12"
					},
					{
						"name":"134510424 ASB13; (RefSeq) ankyrin repeat and SOCS box protein 13\tK10335 ASB13; ankyrin repeat and SOCS box protein 13"
					},
					{
						"name":"134521479 ASB14; (RefSeq) ankyrin repeat and SOCS box protein 14\tK10336 ASB14; ankyrin repeat and SOCS box protein 14"
					},
					{
						"name":"134510241 ASB15; (RefSeq) ankyrin repeat and SOCS box protein 15\tK10337 ASB15; ankyrin repeat and SOCS box protein 15"
					},
					{
						"name":"134524567 ASB16; (RefSeq) ankyrin repeat and SOCS box protein 16\tK10338 ASB16; ankyrin repeat and SOCS box protein 16"
					},
					{
						"name":"134518875 ASB18; (RefSeq) ankyrin repeat and SOCS box protein 18 isoform X1\tK10340 ASB18; ankyrin repeat and SOCS box protein 18"
					},
					{
						"name":"134518990 WSB1; (RefSeq) WD repeat and SOCS box-containing protein 1\tK10341 WSB1; WD repeat and SOCS box-containing protein 1"
					},
					{
						"name":"134523056 WSB2; (RefSeq) WD repeat and SOCS box-containing protein 2\tK10342 WSB2; WD repeat and SOCS box-containing protein 2"
					},
					{
						"name":"134517901 SPSB4; (RefSeq) SPRY domain-containing SOCS box protein 4\tK10343 SPSB1_4; SPRY domain-containing SOCS box protein 1\/4"
					},
					{
						"name":"134524113 SPSB1; (RefSeq) SPRY domain-containing SOCS box protein 1\tK10343 SPSB1_4; SPRY domain-containing SOCS box protein 1\/4"
					},
					{
						"name":"134520061 SPSB3; (RefSeq) SPRY domain-containing SOCS box protein 3\tK10345 SPSB3; SPRY domain-containing SOCS box protein 3"
					},
					{
						"name":"134519738 RAB40C; (RefSeq) ras-related protein Rab-40C\tK07928 RAB40; Ras-related protein Rab-40"
					},
					{
						"name":"134523226 RAB40B; (RefSeq) ras-related protein Rab-40B isoform X1\tK07928 RAB40; Ras-related protein Rab-40"
					},
					{
						"name":"134519341 LRRC41; (RefSeq) leucine-rich repeat-containing protein 41 isoform X1\tK10347 LRRC41; leucine-rich repeat-containing protein 41"
					},
					{
						"name":"134515248 RSPRY1; (RefSeq) RING finger and SPRY domain-containing protein 1\tK23332 RSPRY1; RING finger and SPRY domain-containing protein 1"
					},
					{
						"name":"134512624 ankyrin repeat domain-containing protein 9-like isoform X1\tK25208 ANKRD9; ankyrin repeat domain-containing protein 9"
					},
					{
						"name":"134514815 ANKRD9; (RefSeq) ankyrin repeat domain-containing protein 9\tK25208 ANKRD9; ankyrin repeat domain-containing protein 9"
					},
					{
						"name":"134515139 KLHDC1; (RefSeq) kelch domain-containing protein 1\tK25810 KLHDC1; kelch domain-containing protein 1"
					}
					]
				}
				]
			},
			{
				"name":"Cul7 complex",
				"children":[
				{
					"name":"Ring finger protein",
					"children":[
					{
						"name":"134509872 RBX1; (RefSeq) E3 ubiquitin-protein ligase RBX1\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
					}
					]
				},
				{
					"name":"Cullin"
				},
				{
					"name":"Adaptor protein",
					"children":[
					{
						"name":"134521747 SKP1; (RefSeq) S-phase kinase-associated protein 1\tK03094 SKP1; S-phase kinase-associated protein 1"
					}
					]
				},
				{
					"name":"Target recognizing subunit",
					"children":[
					{
						"name":"134522722 FBXW8; (RefSeq) F-box\/WD repeat-containing protein 8\tK10264 FBXW8; F-box and WD-40 domain protein 8"
					}
					]
				}
				]
			},
			{
				"name":"Cul8 complex",
				"children":[
				{
					"name":"Ring finger protein",
					"children":[
					{
						"name":"134509872 RBX1; (RefSeq) E3 ubiquitin-protein ligase RBX1\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
					}
					]
				},
				{
					"name":"Cullin"
				},
				{
					"name":"Adaptor protein"
				},
				{
					"name":"Target recognizing subunit"
				}
				]
			},
			{
				"name":"Cul9 complex",
				"children":[
				{
					"name":"Ring finger protein",
					"children":[
					{
						"name":"134509872 RBX1; (RefSeq) E3 ubiquitin-protein ligase RBX1\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
					}
					]
				},
				{
					"name":"Cullin",
					"children":[
					{
						"name":"134512545 cullin-9-like isoform X1\tK11970 CUL9; cullin 9"
					}
					]
				}
				]
			},
			{
				"name":"APC\/C",
				"children":[
				{
					"name":"Ring finger protein",
					"children":[
					{
						"name":"134523221 ANAPC11; (RefSeq) anaphase-promoting complex subunit 11\tK03358 APC11; anaphase-promoting complex subunit 11"
					}
					]
				},
				{
					"name":"Cullin",
					"children":[
					{
						"name":"134523934 ANAPC2; (RefSeq) anaphase-promoting complex subunit 2\tK03349 APC2; anaphase-promoting complex subunit 2"
					}
					]
				},
				{
					"name":"Target recognizing subunit",
					"children":[
					{
						"name":"134519259 CDC20; (RefSeq) cell division cycle protein 20 homolog isoform X1\tK03363 CDC20; cell division cycle 20, cofactor of APC complex"
					},
					{
						"name":"134526351 FZR1; (RefSeq) fizzy-related protein homolog isoform X1\tK03364 CDH1; cell division cycle 20-like protein 1, cofactor of APC complex"
					}
					]
				},
				{
					"name":"Other subunits",
					"children":[
					{
						"name":"134512517 ANAPC1; (RefSeq) anaphase-promoting complex subunit 1 isoform X1\tK03348 APC1; anaphase-promoting complex subunit 1"
					},
					{
						"name":"134524443 CDC27; (RefSeq) cell division cycle protein 27 homolog isoform X1\tK03350 APC3; anaphase-promoting complex subunit 3"
					},
					{
						"name":"134516204 anaphase-promoting complex subunit 4-like isoform X1\tK03351 APC4; anaphase-promoting complex subunit 4"
					},
					{
						"name":"134522919 ANAPC5; (RefSeq) anaphase-promoting complex subunit 5\tK03352 APC5; anaphase-promoting complex subunit 5"
					},
					{
						"name":"134517167 CDC16; (RefSeq) cell division cycle protein 16 homolog isoform X1\tK03353 APC6; anaphase-promoting complex subunit 6"
					},
					{
						"name":"134523093 ANAPC7; (RefSeq) anaphase-promoting complex subunit 7\tK03354 APC7; anaphase-promoting complex subunit 7"
					},
					{
						"name":"134522039 CDC23; (RefSeq) cell division cycle protein 23 homolog\tK03355 APC8; anaphase-promoting complex subunit 8"
					},
					{
						"name":"134516069 ANAPC10; (RefSeq) anaphase-promoting complex subunit 10\tK03357 APC10; anaphase-promoting complex subunit 10"
					},
					{
						"name":"134523604 CDC26; (RefSeq) anaphase-promoting complex subunit CDC26\tK03359 APC12; anaphase-promoting complex subunit 12"
					},
					{
						"name":"134517979 ANAPC13; (RefSeq) anaphase-promoting complex subunit 13\tK12456 APC13; anaphase-promoting complex subunit 13"
					},
					{
						"name":"134514083 ANAPC15; (RefSeq) anaphase-promoting complex subunit 15\tK25228 APC15; anaphase-promoting complex subunit 15"
					},
					{
						"name":"134516808 ANAPC16; (RefSeq) anaphase-promoting complex subunit 16 isoform X1\tK25229 APC16; anaphase-promoting complex subunit 16"
					}
					]
				}
				]
			},
			{
				"name":"BRCC complex",
				"children":[
				{
					"name":"134524464 BRCA1; (RefSeq) breast cancer type 1 susceptibility protein isoform X1\tK10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]"
				},
				{
					"name":"134524555 BRCA2; (RefSeq) breast cancer type 2 susceptibility protein\tK08775 BRCA2; breast cancer 2 susceptibility protein"
				},
				{
					"name":"134521007 BRCC3; (RefSeq) lys-63-specific deubiquitinase BRCC36\tK11864 BRCC3; BRCA1\/BRCA2-containing complex subunit 3 [EC:3.4.19.-]"
				},
				{
					"name":"134518957 BARD1; (RefSeq) BRCA1-associated RING domain protein 1 isoform X1\tK10683 BARD1; BRCA1-associated RING domain protein 1"
				},
				{
					"name":"134512855 BABAM2; (RefSeq) BRISC and BRCA1-A complex member 2\tK12173 BRE; BRCA1-A complex subunit BRE"
				},
				{
					"name":"134515233 RAD51; (RefSeq) DNA repair protein RAD51 homolog 1\tK04482 RAD51; DNA repair protein RAD51"
				}
				]
			},
			{
				"name":"KPC complex",
				"children":[
				{
					"name":"134521721 RNF123; (RefSeq) E3 ubiquitin-protein ligase RNF123 isoform X1\tK12169 KPC1; Kip1 ubiquitination-promoting complex protein 1 [EC:2.3.2.27]"
				},
				{
					"name":"134523694 UBAC1; (RefSeq) ubiquitin-associated domain-containing protein 1 isoform X1\tK12174 KPC2; Kip1 ubiquitination-promoting complex protein 2"
				}
				]
			},
			{
				"name":"LUBAC complex",
				"children":[
				{
					"name":"134512323 SHARPIN; (RefSeq) LOW QUALITY PROTEIN: sharpin\tK10630 RBCK1; RanBP-type and C3HC4-type zinc finger-containing protein 1 [EC:2.3.2.31]"
				}
				]
			},
			{
				"name":"CTLH complex",
				"children":[
				{
					"name":"134516196 RMND5A; (RefSeq) E3 ubiquitin-protein transferase RMND5A\tK23333 RMND5; E3 ubiquitin-protein transferase RMND5 [EC:2.3.2.27]"
				},
				{
					"name":"134511604 RANBP9; (RefSeq) ran-binding protein 9 isoform X1\tK23334 RANBP9_10; Ran-binding protein 9\/10"
				},
				{
					"name":"134515253 RANBP10; (RefSeq) ran-binding protein 10 isoform X1\tK23334 RANBP9_10; Ran-binding protein 9\/10"
				},
				{
					"name":"134517961 ARMC8; (RefSeq) armadillo repeat-containing protein 8 isoform X1\tK23336 ARMC8; armadillo repeat-containing protein 8"
				},
				{
					"name":"134510413 MKLN1; (RefSeq) muskelin isoform X1\tK23337 MKLN1; muskelin"
				},
				{
					"name":"134516440 MAEA; (RefSeq) E3 ubiquitin-protein transferase MAEA isoform X1\tK18624 MAEA; macrophage erythroblast attacher"
				},
				{
					"name":"134519894 GID4; (RefSeq) glucose-induced degradation protein 4 homolog\tK23335 GID4; glucose-induced degradation protein 4"
				},
				{
					"name":"134522305 GID8; (RefSeq) glucose-induced degradation protein 8 homolog\tK23338 GID8; glucose-induced degradation protein 8"
				},
				{
					"name":"134512625 YPEL5; (RefSeq) protein yippee-like 5\tK23339 YPEL5; protein yippee-like 5"
				},
				{
					"name":"134512655 WDR26; (RefSeq) WD repeat-containing protein 26 isoform X1\tK22382 WDR26; WD repeat-containing protein 26"
				}
				]
			},
			{
				"name":"ERAD complex",
				"children":[
				{
					"name":"134515349 AMFR; (RefSeq) E3 ubiquitin-protein ligase AMFR isoform X1\tK10636 AMFR; E3 ubiquitin-protein ligase AMFR [EC:2.3.2.36]"
				},
				{
					"name":"134510543 TMUB1; (RefSeq) transmembrane and ubiquitin-like domain-containing protein 1\tK23340 TMUB; transmembrane and ubiquitin-like domain-containing protein"
				},
				{
					"name":"134524349 TMUB2; (RefSeq) transmembrane and ubiquitin-like domain-containing protein 2\tK23340 TMUB; transmembrane and ubiquitin-like domain-containing protein"
				},
				{
					"name":"134517206 ERLIN1; (RefSeq) LOW QUALITY PROTEIN: erlin-1\tK23341 ERLIN; erlin"
				},
				{
					"name":"134526536 ERLIN2; (RefSeq) erlin-2\tK23341 ERLIN; erlin"
				}
				]
			},
			{
				"name":"LMBR1L-GP78-UBAC2 complex",
				"children":[
				{
					"name":"134526913 LMBR1L; (RefSeq) protein LMBR1L isoform X1\tK25215 LMBR1L; protein LMBR1L"
				},
				{
					"name":"134515349 AMFR; (RefSeq) E3 ubiquitin-protein ligase AMFR isoform X1\tK10636 AMFR; E3 ubiquitin-protein ligase AMFR [EC:2.3.2.36]"
				},
				{
					"name":"134516582 UBAC2; (RefSeq) ubiquitin-associated domain-containing protein 2 isoform X1\tK25216 UBAC2; ubiquitin-associated domain-containing protein 2"
				}
				]
			},
			{
				"name":"STUB1-CHIC2  complex",
				"children":[
				{
					"name":"134519878 STUB1; (RefSeq) E3 ubiquitin-protein ligase CHIP\tK09561 STUB1; STIP1 homology and U-box containing protein 1 [EC:2.3.2.27]"
				},
				{
					"name":"134516091 CHIC2; (RefSeq) cysteine-rich hydrophobic domain-containing protein 2\tK28185 CHIC2; cysteine-rich hydrophobic domain-containing protein 2"
				}
				]
			},
			{
				"name":"SLX5-SLX8 complex"
			},
			{
				"name":"Multi subunit type E3 associated proteins",
				"children":[
				{
					"name":"134510114 CAND1; (RefSeq) cullin-associated NEDD8-dissociated protein 1\tK17263 CAND1; cullin-associated NEDD8-dissociated protein 1"
				},
				{
					"name":"134521725 cullin-associated NEDD8-dissociated protein 1-like isoform X1\tK24172 CAND2; cullin-associated NEDD8-dissociated protein 2"
				},
				{
					"name":"134512709 COMMD1; (RefSeq) COMM domain-containing protein 1\tK22557 COMMD1; COMM domain containing 1"
				},
				{
					"name":"134517467 COMMD2; (RefSeq) COMM domain-containing protein 2 isoform X1\tK22558 COMMD2; COMM domain containing 2"
				},
				{
					"name":"134511145 COMMD3; (RefSeq) COMM domain-containing protein 3\tK22559 COMMD3; COMM domain containing 3"
				},
				{
					"name":"134520422 COMMD4; (RefSeq) COMM domain-containing protein 4 isoform X1\tK22560 COMMD4; COMM domain containing 4"
				},
				{
					"name":"134521011 COMMD5; (RefSeq) COMM domain-containing protein 5 isoform X1\tK22561 COMMD5; COMM domain containing 5"
				},
				{
					"name":"134515969 COMMD6; (RefSeq) COMM domain-containing protein 6\tK22562 COMMD6; COMM domain containing 6"
				},
				{
					"name":"134522509 COMMD7; (RefSeq) COMM domain-containing protein 7\tK22563 COMMD7; COMM domain containing 7"
				},
				{
					"name":"134515817 COMMD8; (RefSeq) COMM domain-containing protein 8 isoform X1\tK22564 COMMD8; COMM domain containing 8"
				},
				{
					"name":"134514741 COMMD9; (RefSeq) COMM domain-containing protein 9\tK22565 COMMD9; COMM domain containing 9"
				},
				{
					"name":"134508594 COMMD10; (RefSeq) COMM domain-containing protein 10\tK22566 COMMD10; COMM domain containing 10"
				},
				{
					"name":"134516164 DDRGK1; (RefSeq) DDRGK domain-containing protein 1\tK23344 DDRGK1; DDRGK domain-containing protein 1"
				},
				{
					"name":"134519331 GLMN; (RefSeq) glomulin isoform X1\tK23345 GLMN; glomulin"
				},
				{
					"name":"134519164 IVNS1ABP; (RefSeq) influenza virus NS1A-binding protein\tK15046 IVNS1ABP; influenza virus NS1A-binding protein"
				},
				{
					"name":"134517217 UBXN7; (RefSeq) UBX domain-containing protein 7\tK24350 UBXN7; UBX domain-containing protein 7"
				},
				{
					"name":"134513087 PACRG; (RefSeq) parkin coregulated gene protein isoform X1\tK26163 PACRG; parkin coregulated gene protein"
				},
				{
					"name":"134508340 UBAP2; (RefSeq) ubiquitin-associated protein 2 isoform X1\tK26545 UBAP2; ubiquitin-associated protein 2"
				},
				{
					"name":"134526098 UBAP2L; (RefSeq) ubiquitin-associated protein 2-like isoform X1\tK26545 UBAP2; ubiquitin-associated protein 2"
				},
				{
					"name":"134514060 UEVLD; (RefSeq) ubiquitin-conjugating enzyme E2 variant 3\tK28518 UEVLD; ubiquitin-conjugating enzyme E2 variant 3"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Deubiquitinating enzyme (DUB)",
		"children":[
		{
			"name":"Ubiquitin-specific proteases (UBPs)",
			"children":[
			{
				"name":"UCH",
				"children":[
				{
					"name":"134516606 UCHL1; (RefSeq) ubiquitin carboxyl-terminal hydrolase isozyme L1\tK05611 UCHL1; ubiquitin carboxyl-terminal hydrolase L1 [EC:3.4.19.12]"
				},
				{
					"name":"134521487 BAP1; (RefSeq) ubiquitin carboxyl-terminal hydrolase BAP1 isoform X1\tK08588 BAP1; ubiquitin carboxyl-terminal hydrolase BAP1 [EC:3.4.19.12]"
				},
				{
					"name":"134515973 UCHL3; (RefSeq) ubiquitin carboxyl-terminal hydrolase isozyme L3\tK05609 UCHL3; ubiquitin carboxyl-terminal hydrolase L3 [EC:3.4.19.12]"
				},
				{
					"name":"134519777 UCHL5; (RefSeq) LOW QUALITY PROTEIN: ubiquitin carboxyl-terminal hydrolase isozyme L5\tK05610 UCHL5; ubiquitin carboxyl-terminal hydrolase L5 [EC:3.4.19.12]"
				}
				]
			},
			{
				"name":"UBP\/USP",
				"children":[
				{
					"name":"134512294 ubiquitin carboxyl-terminal hydrolase CYLD-like isoform X1\tK08601 CYLD; ubiquitin carboxyl-terminal hydrolase CYLD [EC:3.4.19.12]"
				},
				{
					"name":"134515419 CYLD; (RefSeq) ubiquitin carboxyl-terminal hydrolase CYLD isoform X1\tK08601 CYLD; ubiquitin carboxyl-terminal hydrolase CYLD [EC:3.4.19.12]"
				},
				{
					"name":"134519138 USP1; (RefSeq) ubiquitin carboxyl-terminal hydrolase 1\tK11832 USP1; ubiquitin carboxyl-terminal hydrolase 1 [EC:3.4.19.12]"
				},
				{
					"name":"134525018 USP2; (RefSeq) ubiquitin carboxyl-terminal hydrolase 2 isoform X1\tK11833 USP2; ubiquitin carboxyl-terminal hydrolase 2 [EC:3.4.19.12]"
				},
				{
					"name":"134520448 USP3; (RefSeq) ubiquitin carboxyl-terminal hydrolase 3 isoform X1\tK11986 USP3; ubiquitin carboxyl-terminal hydrolase 3 [EC:3.4.19.12]"
				},
				{
					"name":"134521708 USP4; (RefSeq) ubiquitin carboxyl-terminal hydrolase 4 isoform X1\tK11835 USP4_11; ubiquitin carboxyl-terminal hydrolase 4\/11 [EC:3.4.19.12]"
				},
				{
					"name":"134517485 USP13; (RefSeq) ubiquitin carboxyl-terminal hydrolase 13\tK11836 USP5_13; ubiquitin carboxyl-terminal hydrolase 5\/13 [EC:3.4.19.12]"
				},
				{
					"name":"134524062 USP5; (RefSeq) ubiquitin carboxyl-terminal hydrolase 5 isoform X1\tK11836 USP5_13; ubiquitin carboxyl-terminal hydrolase 5\/13 [EC:3.4.19.12]"
				},
				{
					"name":"134518434 USP32; (RefSeq) ubiquitin carboxyl-terminal hydrolase 32 isoform X1\tK11837 USP6_32; ubiquitin carboxyl-terminal hydrolase 6\/32 [EC:3.4.19.12]"
				},
				{
					"name":"134519283 USP7; (RefSeq) ubiquitin carboxyl-terminal hydrolase 7\tK11838 USP7; ubiquitin carboxyl-terminal hydrolase 7 [EC:3.4.19.12]"
				},
				{
					"name":"134520520 USP8; (RefSeq) ubiquitin carboxyl-terminal hydrolase 8 isoform X1\tK11839 USP8; ubiquitin carboxyl-terminal hydrolase 8 [EC:3.4.19.12]"
				},
				{
					"name":"134519585 USP9X; (RefSeq) probable ubiquitin carboxyl-terminal hydrolase FAF-X isoform X1\tK11840 USP9_24; ubiquitin carboxyl-terminal hydrolase 9\/24 [EC:3.4.19.12]"
				},
				{
					"name":"134520193 USP24; (RefSeq) ubiquitin carboxyl-terminal hydrolase 24 isoform X1\tK11840 USP9_24; ubiquitin carboxyl-terminal hydrolase 9\/24 [EC:3.4.19.12]"
				},
				{
					"name":"134515604 USP10; (RefSeq) ubiquitin carboxyl-terminal hydrolase 10\tK11841 USP10; ubiquitin carboxyl-terminal hydrolase 10 [EC:3.4.19.12]"
				},
				{
					"name":"134514216 USP12; (RefSeq) ubiquitin carboxyl-terminal hydrolase 12 isoform X1\tK11842 USP12_46; ubiquitin carboxyl-terminal hydrolase 12\/46 [EC:3.4.19.12]"
				},
				{
					"name":"134515978 USP46; (RefSeq) ubiquitin carboxyl-terminal hydrolase 46 isoform X1\tK11842 USP12_46; ubiquitin carboxyl-terminal hydrolase 12\/46 [EC:3.4.19.12]"
				},
				{
					"name":"134520605 ubiquitin carboxyl-terminal hydrolase 12-like isoform X1\tK11842 USP12_46; ubiquitin carboxyl-terminal hydrolase 12\/46 [EC:3.4.19.12]"
				},
				{
					"name":"134511914 USP14; (RefSeq) ubiquitin carboxyl-terminal hydrolase 14 isoform X1\tK11843 USP14; ubiquitin carboxyl-terminal hydrolase 14 [EC:3.4.19.12]"
				},
				{
					"name":"134510142 USP15; (RefSeq) ubiquitin carboxyl-terminal hydrolase 15 isoform X1\tK21343 USP15; ubiquitin carboxyl-terminal hydrolase 15 [EC:3.4.19.12]"
				},
				{
					"name":"134513355 USP45; (RefSeq) ubiquitin carboxyl-terminal hydrolase 45 isoform X1\tK11844 USP16_45; ubiquitin carboxyl-terminal hydrolase 16\/45 [EC:3.4.19.12]"
				},
				{
					"name":"134521028 USP16; (RefSeq) ubiquitin carboxyl-terminal hydrolase 16\tK11844 USP16_45; ubiquitin carboxyl-terminal hydrolase 16\/45 [EC:3.4.19.12]"
				},
				{
					"name":"134526805 USP18; (RefSeq) ubl carboxyl-terminal hydrolase 18\tK11846 USP18_41; ubiquitin carboxyl-terminal hydrolase 18\/41 [EC:3.4.19.12]"
				},
				{
					"name":"134521344 USP19; (RefSeq) ubiquitin carboxyl-terminal hydrolase 19 isoform X1\tK11847 USP19; ubiquitin carboxyl-terminal hydrolase 19 [EC:3.4.19.12]"
				},
				{
					"name":"134520152 USP33; (RefSeq) ubiquitin carboxyl-terminal hydrolase 33 isoform X1\tK11848 USP20_33; ubiquitin carboxyl-terminal hydrolase 20\/33 [EC:3.4.19.12]"
				},
				{
					"name":"134523945 USP20; (RefSeq) ubiquitin carboxyl-terminal hydrolase 20 isoform X1\tK11848 USP20_33; ubiquitin carboxyl-terminal hydrolase 20\/33 [EC:3.4.19.12]"
				},
				{
					"name":"134525948 USP21; (RefSeq) ubiquitin carboxyl-terminal hydrolase 21 isoform X1\tK21634 USP21; ubiquitin carboxyl-terminal hydrolase 21 [EC:3.4.19.12]"
				},
				{
					"name":"134519172 USP22; (RefSeq) ubiquitin carboxyl-terminal hydrolase 22 isoform X1\tK11366 USP22_27_51; ubiquitin carboxyl-terminal hydrolase 22\/27\/51 [EC:3.4.19.12]"
				},
				{
					"name":"134521195 USP25; (RefSeq) ubiquitin carboxyl-terminal hydrolase 25 isoform X1\tK11849 USP25; ubiquitin carboxyl-terminal hydrolase 25 [EC:3.4.19.12]"
				},
				{
					"name":"134518616 USP37; (RefSeq) ubiquitin carboxyl-terminal hydrolase 37\tK11850 USP26_29_37; ubiquitin carboxyl-terminal hydrolase 26\/29\/37 [EC:3.4.19.12]"
				},
				{
					"name":"134525083 USP28; (RefSeq) ubiquitin carboxyl-terminal hydrolase 28 isoform X1\tK21122 USP28; ubiquitin carboxyl-terminal hydrolase 28 [EC:3.4.19.12]"
				},
				{
					"name":"134522782 USP30; (RefSeq) ubiquitin carboxyl-terminal hydrolase 30 isoform X1\tK11851 USP30; ubiquitin carboxyl-terminal hydrolase 30 [EC:3.4.19.12]"
				},
				{
					"name":"134520216 USP31; (RefSeq) ubiquitin carboxyl-terminal hydrolase 31\tK11852 USP31; ubiquitin carboxyl-terminal hydrolase 31 [EC:3.4.19.12]"
				},
				{
					"name":"134513973 USP34; (RefSeq) ubiquitin carboxyl-terminal hydrolase 34 isoform X1\tK11853 USP34; ubiquitin carboxyl-terminal hydrolase 34 [EC:3.4.19.12]"
				},
				{
					"name":"134511856 USP35; (RefSeq) ubiquitin carboxyl-terminal hydrolase 35\tK11854 USP35_38; ubiquitin carboxyl-terminal hydrolase 35\/38 [EC:3.4.19.12]"
				},
				{
					"name":"134516688 USP38; (RefSeq) ubiquitin carboxyl-terminal hydrolase 38\tK11854 USP35_38; ubiquitin carboxyl-terminal hydrolase 35\/38 [EC:3.4.19.12]"
				},
				{
					"name":"134519942 USP42; (RefSeq) ubiquitin carboxyl-terminal hydrolase 42 isoform X1\tK11855 USP36_42; ubiquitin carboxyl-terminal hydrolase 36\/42 [EC:3.4.19.12]"
				},
				{
					"name":"134523176 USP36; (RefSeq) ubiquitin carboxyl-terminal hydrolase 36\tK11855 USP36_42; ubiquitin carboxyl-terminal hydrolase 36\/42 [EC:3.4.19.12]"
				},
				{
					"name":"134518355 USP40; (RefSeq) ubiquitin carboxyl-terminal hydrolase 40 isoform X1\tK11869 USP40; ubiquitin carboxyl-terminal hydrolase 40 [EC:3.4.19.12]"
				},
				{
					"name":"134523517 USP43; (RefSeq) ubiquitin carboxyl-terminal hydrolase 43\tK11856 USP43; ubiquitin carboxyl-terminal hydrolase 43 [EC:3.4.19.12]"
				},
				{
					"name":"134510014 USP44; (RefSeq) ubiquitin carboxyl-terminal hydrolase 44 isoform X1\tK11834 USP44_49; ubiquitin carboxyl-terminal hydrolase 44\/49 [EC:3.4.19.12]"
				},
				{
					"name":"134525541 USP49; (RefSeq) ubiquitin carboxyl-terminal hydrolase 49\tK11834 USP44_49; ubiquitin carboxyl-terminal hydrolase 44\/49 [EC:3.4.19.12]"
				},
				{
					"name":"134514106 USP47; (RefSeq) ubiquitin carboxyl-terminal hydrolase 47 isoform X1\tK11857 USP47; ubiquitin carboxyl-terminal hydrolase 47 [EC:3.4.19.12]"
				},
				{
					"name":"134524061 USP48; (RefSeq) ubiquitin carboxyl-terminal hydrolase 48 isoform X1\tK11858 USP48; ubiquitin carboxyl-terminal hydrolase 48 [EC:3.4.19.12]"
				},
				{
					"name":"134520521 USP50; (RefSeq) LOW QUALITY PROTEIN: inactive ubiquitin carboxyl-terminal hydrolase 50\tK28833 USP50; ubiquitin carboxyl-terminal hydrolase 50 [EC:3.4.19.12]"
				},
				{
					"name":"134516836 USP54; (RefSeq) inactive ubiquitin carboxyl-terminal hydrolase 54 isoform X1\tK27920 USP54; ubiquitin carboxyl-terminal hydrolase 54 [EC:3.4.19.12]"
				}
				]
			},
			{
				"name":"OTU",
				"children":[
				{
					"name":"134509792 OTUB1; (RefSeq) ubiquitin thioesterase OTUB1\tK09602 OTUB1; ubiquitin thioesterase protein OTUB1 [EC:3.4.19.12]"
				},
				{
					"name":"134524178 OTUD3; (RefSeq) OTU domain-containing protein 3\tK13717 OTUD3; OTU domain-containing protein 3 [EC:3.4.19.12]"
				},
				{
					"name":"134509480 OTUD5; (RefSeq) OTU domain-containing protein 5 isoform X1\tK12655 OTUD5; OTU domain-containing protein 5 [EC:3.4.19.12]"
				},
				{
					"name":"134512113 OTUD6B; (RefSeq) deubiquitinase OTUD6B\tK18342 OTUD6; OTU domain-containing protein 6 [EC:3.4.19.12]"
				},
				{
					"name":"134520443 OTUD7A; (RefSeq) OTU domain-containing protein 7A isoform X1\tK11860 OTUD7A_B; OTU domain-containing protein 7 [EC:3.4.19.12]"
				},
				{
					"name":"134525802 OTUD7B; (RefSeq) OTU domain-containing protein 7B\tK11860 OTUD7A_B; OTU domain-containing protein 7 [EC:3.4.19.12]"
				},
				{
					"name":"134511726 OTULIN; (RefSeq) ubiquitin thioesterase otulin isoform X1\tK18343 OTULIN; ubiquitin thioesterase otulin [EC:3.4.19.12]"
				},
				{
					"name":"134513199 TNFAIP3; (RefSeq) tumor necrosis factor alpha-induced protein 3\tK11859 TNFAIP3; tumor necrosis factor, alpha-induced protein 3 [EC:3.4.19.12]"
				},
				{
					"name":"134512032 VCPIP1; (RefSeq) deubiquitinating protein VCPIP1\tK11861 VCPIP1; deubiquitinating protein VCIP135 [EC:3.4.19.12]"
				},
				{
					"name":"134518041 ZRANB1; (RefSeq) ubiquitin thioesterase ZRANB1\tK11862 ZRANB1; ubiquitin thioesterase ZRANB1 [EC:3.4.19.12]"
				}
				]
			},
			{
				"name":"MJD",
				"children":[
				{
					"name":"134514570 ATXN3; (RefSeq) ataxin-3 isoform X1\tK11863 ATXN3; ataxin-3 [EC:3.4.22.-]"
				},
				{
					"name":"134507746 JOSD2; (RefSeq) josephin-2\tK15235 JOSD; josephin [EC:3.4.19.12]"
				},
				{
					"name":"134509840 JOSD1; (RefSeq) josephin-1\tK15235 JOSD; josephin [EC:3.4.19.12]"
				}
				]
			},
			{
				"name":"MINDY",
				"children":[
				{
					"name":"134520525 MINDY2; (RefSeq) ubiquitin carboxyl-terminal hydrolase MINDY-2 isoform X1\tK01309 MINDY1_2; ubiquitin carboxyl-terminal hydrolase MINDY-1\/2 [EC:3.4.19.12]"
				},
				{
					"name":"134525995 MINDY1; (RefSeq) ubiquitin carboxyl-terminal hydrolase MINDY-1\tK01309 MINDY1_2; ubiquitin carboxyl-terminal hydrolase MINDY-1\/2 [EC:3.4.19.12]"
				},
				{
					"name":"134511007 MINDY4; (RefSeq) probable ubiquitin carboxyl-terminal hydrolase MINDY-4 isoform X1\tK22647 MINDY3_4; ubiquitin carboxyl-terminal hydrolase MINDY-3\/4 [EC:3.4.19.12]"
				},
				{
					"name":"134511177 MINDY3; (RefSeq) ubiquitin carboxyl-terminal hydrolase MINDY-3 isoform X1\tK22647 MINDY3_4; ubiquitin carboxyl-terminal hydrolase MINDY-3\/4 [EC:3.4.19.12]"
				},
				{
					"name":"134517233 MINDY4B; (RefSeq) inactive ubiquitin carboxyl-terminal hydrolase MINDY-4B\tK22647 MINDY3_4; ubiquitin carboxyl-terminal hydrolase MINDY-3\/4 [EC:3.4.19.12]"
				}
				]
			},
			{
				"name":"JAMM",
				"children":[
				{
					"name":"134521007 BRCC3; (RefSeq) lys-63-specific deubiquitinase BRCC36\tK11864 BRCC3; BRCA1\/BRCA2-containing complex subunit 3 [EC:3.4.19.-]"
				},
				{
					"name":"134519677 MYSM1; (RefSeq) deubiquitinase MYSM1 isoform X1\tK11865 MYSM1; histone H2A deubiquitinase [EC:3.4.19.-]"
				},
				{
					"name":"134526364 MPND; (RefSeq) MPN domain-containing protein isoform X1\tK24173 MPND; MPN domain-containing protein"
				},
				{
					"name":"134518623 PSMD14; (RefSeq) 26S proteasome non-ATPase regulatory subunit 14\tK03030 PSMD14; 26S proteasome regulatory subunit N11"
				},
				{
					"name":"134526611 STAMBP; (RefSeq) STAM-binding protein isoform X1\tK11866 STAMBP; STAM-binding protein [EC:3.4.19.12]"
				},
				{
					"name":"134517578 STAMBPL1; (RefSeq) AMSH-like protease\tK11867 STAMBPL1; AMSH-like protease [EC:3.4.19.12]"
				}
				]
			},
			{
				"name":"PPPDE",
				"children":[
				{
					"name":"134512977 DESI2; (RefSeq) deubiquitinase DESI2\tK22763 DESI2; deubiquitinase DESI2 [EC:3.4.19.12]"
				},
				{
					"name":"134514095 deubiquitinase DESI2-like isoform X1\tK22763 DESI2; deubiquitinase DESI2 [EC:3.4.19.12]"
				}
				]
			},
			{
				"name":"ZUFSP",
				"children":[
				{
					"name":"134513285 ZUP1; (RefSeq) zinc finger-containing ubiquitin peptidase 1\tK24134 ZUP1; zinc finger-containing ubiquitin peptidase 1 [EC:3.4.19.12]"
				}
				]
			},
			{
				"name":"BRISC complex",
				"children":[
				{
					"name":"134517440 ABRAXAS2; (RefSeq) BRISC complex subunit Abraxas 2\tK20799 FAM175B; BRISC complex subunit Abro1"
				},
				{
					"name":"134526304 BABAM1; (RefSeq) BRISC and BRCA1-A complex member 1 isoform X1\tK20776 BABAM; BRISC and BRCA1-A complex member 1"
				},
				{
					"name":"134521007 BRCC3; (RefSeq) lys-63-specific deubiquitinase BRCC36\tK11864 BRCC3; BRCA1\/BRCA2-containing complex subunit 3 [EC:3.4.19.-]"
				},
				{
					"name":"134512855 BABAM2; (RefSeq) BRISC and BRCA1-A complex member 2\tK12173 BRE; BRCA1-A complex subunit BRE"
				}
				]
			}
			]
		},
		{
			"name":"UBL-specific proteases (ULPs)",
			"children":[
			{
				"name":"134526852 SENP1; (RefSeq) sentrin-specific protease 1\tK08592 SENP1; sentrin-specific protease 1 [EC:3.4.22.68]"
			},
			{
				"name":"134511580 sentrin-specific protease 2-like\tK03345 SENP2; sentrin-specific protease 2 (axin associating molecule) [EC:3.4.22.68]"
			},
			{
				"name":"134512349 sentrin-specific protease 2-like\tK03345 SENP2; sentrin-specific protease 2 (axin associating molecule) [EC:3.4.22.68]"
			},
			{
				"name":"134517109 sentrin-specific protease 2-like\tK03345 SENP2; sentrin-specific protease 2 (axin associating molecule) [EC:3.4.22.68]"
			},
			{
				"name":"134517876 sentrin-specific protease 2-like\tK03345 SENP2; sentrin-specific protease 2 (axin associating molecule) [EC:3.4.22.68]"
			},
			{
				"name":"134517877 sentrin-specific protease 2-like\tK03345 SENP2; sentrin-specific protease 2 (axin associating molecule) [EC:3.4.22.68]"
			},
			{
				"name":"134516855 SENP5; (RefSeq) sentrin-specific protease 5\tK08594 SENP5; sentrin-specific protease 5 [EC:3.4.22.68]"
			},
			{
				"name":"134513443 SENP6; (RefSeq) sentrin-specific protease 6 isoform X1\tK08595 SENP6; sentrin-specific protease 6 [EC:3.4.22.68]"
			},
			{
				"name":"134522376 SENP7; (RefSeq) sentrin-specific protease 7 isoform X1\tK08596 SENP7; sentrin-specific protease 7 [EC:3.4.22.68]"
			},
			{
				"name":"134520997 SENP8; (RefSeq) sentrin-specific protease 8\tK08597 SENP8; sentrin-specific protease 8 [EC:3.4.22.68]"
			},
			{
				"name":"134515973 UCHL3; (RefSeq) ubiquitin carboxyl-terminal hydrolase isozyme L3\tK05609 UCHL3; ubiquitin carboxyl-terminal hydrolase L3 [EC:3.4.19.12]"
			},
			{
				"name":"134509887 DESI1; (RefSeq) LOW QUALITY PROTEIN: desumoylating isopeptidase 1\tK22762 DESI1; desumoylating isopeptidase 1 [EC:3.4.-.-]"
			},
			{
				"name":"134514397 USPL1; (RefSeq) SUMO-specific isopeptidase USPL1 isoform X1\tK23008 USPL1; SUMO-specific isopeptidase USPL1 [EC:3.4.22.-]"
			},
			{
				"name":"COP9 signalosome (CSN) complex",
				"children":[
				{
					"name":"134523362 GPS1; (RefSeq) COP9 signalosome complex subunit 1\tK12175 GPS1; COP9 signalosome complex subunit 1"
				},
				{
					"name":"134520749 COPS2; (RefSeq) COP9 signalosome complex subunit 2 isoform X1\tK12176 COPS2; COP9 signalosome complex subunit 2"
				},
				{
					"name":"134519399 COPS3; (RefSeq) COP9 signalosome complex subunit 3 isoform X1\tK12177 COPS3; COP9 signalosome complex subunit 3"
				},
				{
					"name":"134516746 COPS4; (RefSeq) COP9 signalosome complex subunit 4\tK12178 COPS4; COP9 signalosome complex subunit 4"
				},
				{
					"name":"134512040 COPS5; (RefSeq) COP9 signalosome complex subunit 5\tK09613 COPS5; COP9 signalosome complex subunit 5 [EC:3.4.-.-]"
				},
				{
					"name":"134517045 COPS7B; (RefSeq) COP9 signalosome complex subunit 7b\tK12180 COPS7; COP9 signalosome complex subunit 7"
				},
				{
					"name":"134524035 COPS7A; (RefSeq) COP9 signalosome complex subunit 7a\tK12180 COPS7; COP9 signalosome complex subunit 7"
				},
				{
					"name":"134518800 COPS8; (RefSeq) COP9 signalosome complex subunit 8\tK12181 COPS8; COP9 signalosome complex subunit 8"
				},
				{
					"name":"134517911 COPS9; (RefSeq) COP9 signalosome complex subunit 9\tK28062 COPS9; COP9 signalosome complex subunit 9"
				}
				]
			}
			]
		}
		]
	}
	]
}