{
	"name":"csab03400",
	"children":[
	{
		"name":"Eukaryotic type",
		"children":[
		{
			"name":"SSBR (single strand breaks repair)",
			"children":[
			{
				"name":"Direct repair",
				"children":[
				{
					"name":"103216705 MGMT; O-6-methylguanine-DNA methyltransferase\tK00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]"
				},
				{
					"name":"103239079 ALKBH2; alkB homolog 2, alpha-ketoglutarate dependent dioxygenase\tK10859 ALKBH2; DNA oxidative demethylase [EC:1.14.11.33]"
				},
				{
					"name":"103237116 ALKBH3; alkB homolog 3, alpha-ketoglutaratedependent dioxygenase\tK10860 ALKBH3; mRNA N1-methyladenine demethylase [EC:1.14.11.54]"
				},
				{
					"name":"103240676 ASCC3; activating signal cointegrator 1 complex subunit 3\tK18663 ASCC3; activating signal cointegrator complex subunit 3 [EC:5.6.2.4]"
				}
				]
			},
			{
				"name":"BER (base exicision repair)",
				"children":[
				{
					"name":"DNA glycosylases",
					"children":[
					{
						"name":"103239082 UNG; uracil DNA glycosylase\tK03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]"
					},
					{
						"name":"103221494 CCNO; cyclin O\tK10861 UDG2; uracil-DNA glycosylase 2 [EC:3.2.2.-]"
					},
					{
						"name":"103238979 TDG; thymine DNA glycosylase\tK20813 TDG; thymine-DNA glycosylase [EC:3.2.2.29]"
					},
					{
						"name":"103225339 MPG; N-methylpurine DNA glycosylase\tK03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]"
					},
					{
						"name":"103238429 SMUG1; single-strand-selective monofunctional uracil-DNA glycosylase 1\tK10800 SMUG1; single-strand selective monofunctional uracil DNA glycosylase [EC:3.2.2.-]"
					},
					{
						"name":"103224913 MUTYH; mutY DNA glycosylase\tK03575 mutY; A\/G-specific adenine glycosylase [EC:3.2.2.31]"
					},
					{
						"name":"103228069 MBD4; methyl-CpG binding domain 4, DNA glycosylase\tK10801 MBD4; methyl-CpG-binding domain protein 4 [EC:3.2.2.-]"
					},
					{
						"name":"103227978 OGG1; 8-oxoguanine DNA glycosylase\tK03660 OGG1; N-glycosylase\/DNA lyase [EC:3.2.2.- 4.2.99.18]"
					},
					{
						"name":"103245295 NEIL1; nei like DNA glycosylase 1\tK10567 NEIL1; endonuclease VIII-like 1 [EC:3.2.2.- 4.2.99.18]"
					},
					{
						"name":"103215321 NEIL2; nei like DNA glycosylase 2\tK10568 NEIL2; endonuclease VIII-like 2 [EC:3.2.2.- 4.2.99.18]"
					},
					{
						"name":"103236567 NEIL3; nei like DNA glycosylase 3\tK10569 NEIL3; endonuclease VIII-like 3 [EC:3.2.2.- 4.2.99.18]"
					},
					{
						"name":"103226630 NTHL1; nth like DNA glycosylase 1\tK10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]"
					}
					]
				},
				{
					"name":"AP endonucleases",
					"children":[
					{
						"name":"103231340 DNA-(apurinic or apyrimidinic site) lyase\tK10771 APEX1; AP endonuclease 1 [EC:3.1.11.2]"
					},
					{
						"name":"103231343 DNA-(apurinic or apyrimidinic site) lyase\tK10771 APEX1; AP endonuclease 1 [EC:3.1.11.2]"
					},
					{
						"name":"103232031 APEX2; apurinic\/apyrimidinic endodeoxyribonuclease 2\tK10772 APEX2; AP endonuclease 2 [EC:3.1.11.2]"
					}
					]
				},
				{
					"name":"Long Patch-BER factors",
					"children":[
					{
						"name":"DNA polymerase delta complex",
						"children":[
						{
							"name":"103235079 transcription factor Spi-B\tK02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]"
						},
						{
							"name":"103226140 POLD2; DNA polymerase delta 2, accessory subunit\tK02328 POLD2; DNA polymerase delta subunit 2"
						},
						{
							"name":"103248038 POLD3; DNA polymerase delta 3, accessory subunit\tK03504 POLD3; DNA polymerase delta subunit 3"
						},
						{
							"name":"103218460 POLD4; DNA polymerase delta 4, accessory subunit\tK03505 POLD4; DNA polymerase delta subunit 4"
						}
						]
					},
					{
						"name":"DNA polymerase epsilon complex",
						"children":[
						{
							"name":"103239455 POLE; DNA polymerase epsilon, catalytic subunit\tK02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]"
						},
						{
							"name":"103228941 POLE2; DNA polymerase epsilon 2, accessory subunit\tK02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]"
						},
						{
							"name":"103218985 POLE3; DNA polymerase epsilon 3, accessory subunit\tK02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]"
						},
						{
							"name":"103220011 POLE4; DNA polymerase epsilon 4, accessory subunit\tK03506 POLE4; DNA polymerase epsilon subunit 4 [EC:2.7.7.7]"
						}
						]
					},
					{
						"name":"103242170 proliferating cell nuclear antigen-like\tK04802 PCNA; proliferating cell nuclear antigen"
					},
					{
						"name":"103246929 PCNA; proliferating cell nuclear antigen\tK04802 PCNA; proliferating cell nuclear antigen"
					},
					{
						"name":"103234213 FEN1; flap structure-specific endonuclease 1\tK04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]"
					},
					{
						"name":"103234960 LIG1; DNA ligase 1\tK10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]"
					}
					]
				},
				{
					"name":"Short Patch-BER factors",
					"children":[
					{
						"name":"103215689 POLB; DNA polymerase beta\tK02330 POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-]"
					},
					{
						"name":"103234789 XRCC1; X-ray repair cross complementing 1\tK10803 XRCC1; DNA-repair protein XRCC1"
					},
					{
						"name":"103242720 LIG3; DNA ligase 3\tK10776 LIG3; DNA ligase 3 [EC:6.5.1.1]"
					}
					]
				},
				{
					"name":"Other BER factors",
					"children":[
					{
						"name":"103229533 TDP1; tyrosyl-DNA phosphodiesterase 1\tK10862 TDP1; tyrosyl-DNA phosphodiesterase 1 [EC:3.1.4.-]"
					},
					{
						"name":"103219297 APTX; aprataxin\tK10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]"
					},
					{
						"name":"103220122 APLF; aprataxin and PNKP like factor\tK13295 APLF; aprataxin and PNK-like factor [EC:3.1.-.-]"
					},
					{
						"name":"103235058 PNKP; polynucleotide kinase 3'-phosphatase\tK08073 PNKP; bifunctional polynucleotide phosphatase\/kinase [EC:3.1.3.32 2.7.1.78]"
					},
					{
						"name":"103237177 high mobility group protein B1\tK10802 HMGB1; high mobility group protein B1"
					},
					{
						"name":"103216413 POLL; DNA polymerase lambda\tK03512 POLL; DNA polymerase lambda [EC:2.7.7.7 4.2.99.-]"
					},
					{
						"name":"103229992 PARP1; poly(ADP-ribose) polymerase 1\tK24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30]"
					},
					{
						"name":"103231336 PARP2; poly(ADP-ribose) polymerase 2\tK28005 PARP2; poly [ADP-ribose] polymerase 2 [EC:2.4.2.30]"
					},
					{
						"name":"103227705 PARP3; poly(ADP-ribose) polymerase family member 3\tK10798 PARP3_4; protein mono-ADP-ribosyltransferase 3\/4 [EC:2.4.2.-]"
					},
					{
						"name":"103249024 PARP4; poly(ADP-ribose) polymerase family member 4\tK10798 PARP3_4; protein mono-ADP-ribosyltransferase 3\/4 [EC:2.4.2.-]"
					}
					]
				}
				]
			},
			{
				"name":"NER (nucleotide excision repair)",
				"children":[
				{
					"name":"GGR (global genome repair) factors",
					"children":[
					{
						"name":"XPC-HR23B-CETN2 complex",
						"children":[
						{
							"name":"103228047 XPC; XPC complex subunit, DNA damage recognition and repair factor\tK10838 XPC; xeroderma pigmentosum group C-complementing protein"
						},
						{
							"name":"103219057 RAD23B; RAD23 homolog B, nucleotide excision repair protein\tK10839 RAD23; UV excision repair protein RAD23"
						},
						{
							"name":"103234004 RAD23A; RAD23 homolog A, nucleotide excision repair protein\tK10839 RAD23; UV excision repair protein RAD23"
						},
						{
							"name":"103232766 CETN2; centrin 2\tK10840 CETN2; centrin-2"
						}
						]
					},
					{
						"name":"Cul4-DDB2 complex",
						"children":[
						{
							"name":"103223367 RBX1; ring-box 1\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
						},
						{
							"name":"103214836 CUL4A; cullin 4A\tK10609 CUL4; cullin 4"
						},
						{
							"name":"103247359 CUL4B; cullin 4B\tK10609 CUL4; cullin 4"
						},
						{
							"name":"103234463 DDB1; damage specific DNA binding protein 1\tK10610 DDB1; DNA damage-binding protein 1"
						},
						{
							"name":"103236219 DDB2; damage specific DNA binding protein 2\tK10140 DDB2; DNA damage-binding protein 2"
						}
						]
					},
					{
						"name":"NER4 complex"
					}
					]
				},
				{
					"name":"TCR (transcription coupled repair) factors",
					"children":[
					{
						"name":"DNA-directed RNA polymerase II complex",
						"children":[
						{
							"name":"103242561 POLR2A; RNA polymerase II subunit A\tK03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]"
						},
						{
							"name":"103235632 POLR2B; RNA polymerase II subunit B\tK03010 RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]"
						},
						{
							"name":"103233063 POLR2C; RNA polymerase II subunit C\tK03011 RPB3; DNA-directed RNA polymerase II subunit RPB3"
						},
						{
							"name":"103216869 POLR2D; RNA polymerase II subunit D\tK03012 RPB4; DNA-directed RNA polymerase II subunit RPB4"
						},
						{
							"name":"103233592 POLR2E; RNA polymerase II subunit E\tK03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1"
						},
						{
							"name":"103223297 POLR2F; RNA polymerase II subunit F\tK03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2"
						},
						{
							"name":"103233885 POLR2G; RNA polymerase II subunit G\tK03015 RPB7; DNA-directed RNA polymerase II subunit RPB7"
						},
						{
							"name":"103221131 POLR2H; RNA polymerase II subunit H\tK03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3"
						},
						{
							"name":"103234557 POLR2I; RNA polymerase II subunit I\tK03017 RPB9; DNA-directed RNA polymerase II subunit RPB9"
						},
						{
							"name":"103234512 POLR2L; RNA polymerase II subunit L\tK03007 RPABC5; DNA-directed RNA polymerases I, II, and III subunit RPABC5"
						},
						{
							"name":"103246673 POLR2J; RNA polymerase II subunit J\tK03008 RPB11; DNA-directed RNA polymerase II subunit RPB11"
						},
						{
							"name":"103237210 POLR2K; RNA polymerase II subunit K\tK03009 RPABC4; DNA-directed RNA polymerases I, II, and III subunit RPABC4"
						}
						]
					},
					{
						"name":"Cul4-CSA complex",
						"children":[
						{
							"name":"103223367 RBX1; ring-box 1\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
						},
						{
							"name":"103214836 CUL4A; cullin 4A\tK10609 CUL4; cullin 4"
						},
						{
							"name":"103247359 CUL4B; cullin 4B\tK10609 CUL4; cullin 4"
						},
						{
							"name":"103234463 DDB1; damage specific DNA binding protein 1\tK10610 DDB1; DNA damage-binding protein 1"
						},
						{
							"name":"103222012 ERCC8; ERCC excision repair 8, CSA ubiquitin ligase complex subunit\tK10570 ERCC8; DNA excision repair protein ERCC-8"
						}
						]
					},
					{
						"name":"Other TCR factor",
						"children":[
						{
							"name":"103215829 DNA excision repair protein ERCC-6\tK10841 ERCC6; DNA excision repair protein ERCC-6"
						},
						{
							"name":"103246488 UVSSA; UV stimulated scaffold protein A\tK23720 UVSSA; UV-stimulated scaffold protein A"
						},
						{
							"name":"103233939 ELOF1; elongation factor 1 homolog\tK25829 ELOF1; transcription elongation factor 1"
						}
						]
					}
					]
				},
				{
					"name":"TFIIH complex",
					"children":[
					{
						"name":"103216880 ERCC3; ERCC excision repair 3, TFIIH core complex helicase subunit\tK10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]"
					},
					{
						"name":"103234861 ERCC2; ERCC excision repair 2, TFIIH core complex helicase subunit\tK10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]"
					},
					{
						"name":"103239237 GTF2H1; general transcription factor IIH subunit 1\tK03141 TFIIH1; transcription initiation factor TFIIH subunit 1"
					},
					{
						"name":"103222816 GTF2H2; general transcription factor IIH subunit 2\tK03142 TFIIH2; transcription initiation factor TFIIH subunit 2"
					},
					{
						"name":"103239334 GTF2H3; general transcription factor IIH subunit 3\tK03143 TFIIH3; transcription initiation factor TFIIH subunit 3"
					},
					{
						"name":"103221812 GTF2H4; general transcription factor IIH subunit 4\tK03144 TFIIH4; transcription initiation factor TFIIH subunit 4"
					},
					{
						"name":"103222774 CDK7; cyclin dependent kinase 7\tK02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]"
					},
					{
						"name":"103224232 CCNH; cyclin H\tK06634 CCNH; cyclin H"
					},
					{
						"name":"103229118 MNAT1; MNAT1, CDK activating kinase assembly factor\tK10842 MNAT1; CDK-activating kinase assembly factor MAT1"
					}
					]
				},
				{
					"name":"RPA (replication factor A)",
					"children":[
					{
						"name":"103242545 RPA1; replication protein A1\tK07466 RFA1; replication factor A1"
					},
					{
						"name":"103225275 RPA2; replication protein A2\tK10739 RFA2; replication factor A2"
					},
					{
						"name":"103226491 RPA3; replication protein A3\tK10740 RPA3; replication factor A3"
					},
					{
						"name":"103232330 RPA4; replication protein A4\tK10741 RPA4; replication factor A4"
					}
					]
				},
				{
					"name":"Other NER factors",
					"children":[
					{
						"name":"103219158 XPA; XPA, DNA damage recognition and repair factor\tK10847 XPA; DNA-repair protein complementing XP-A cells"
					},
					{
						"name":"103234864 ERCC1; ERCC excision repair 1, endonuclease non-catalytic subunit\tK10849 ERCC1; DNA excision repair protein ERCC-1"
					},
					{
						"name":"103228615 ERCC4; ERCC excision repair 4, endonuclease catalytic subunit\tK10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]"
					},
					{
						"name":"103214745 ERCC5; ERCC excision repair 5, endonuclease\tK10846 ERCC5; DNA excision repair protein ERCC-5"
					},
					{
						"name":"103234960 LIG1; DNA ligase 1\tK10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]"
					},
					{
						"name":"103216338 MMS19; MMS19 homolog, cytosolic iron-sulfur assembly component\tK15075 MET18; DNA repair\/transcription protein MET18\/MMS19"
					},
					{
						"name":"103223124 CCDC117; coiled-coil domain containing 117\tK27967 CCDC117; coiled-coil domain-containing protein 117"
					},
					{
						"name":"103241067 CIAO1; cytosolic iron-sulfur assembly component 1\tK24730 CIAO1; cytosolic iron-sulfur protein assembly protein CIAO1"
					},
					{
						"name":"103233137 FAM96B; family with sequence similarity 96 member B\tK26403 CIAO2; cytosolic iron-sulfur assembly component 2"
					},
					{
						"name":"103245500 FAM96A; family with sequence similarity 96 member A\tK26403 CIAO2; cytosolic iron-sulfur assembly component 2"
					},
					{
						"name":"103217971 CUL3; cullin 3\tK03869 CUL3; cullin 3"
					},
					{
						"name":"103248397 CUL5; cullin 5\tK10612 CUL5; cullin 5"
					},
					{
						"name":"103236978 ELOC; elongin C\tK03872 ELOC; elongin-C"
					},
					{
						"name":"103218574 transcription elongation factor B polypeptide 2\tK03873 ELOB; elongin-B"
					},
					{
						"name":"103226961 ELOB; elongin B\tK03873 ELOB; elongin-B"
					},
					{
						"name":"103222465 RNA polymerase II transcription factor SIII subunit A3-like\tK15076 ELOA; elongin-A"
					},
					{
						"name":"103222466 ELOA2; elongin A2\tK15076 ELOA; elongin-A"
					},
					{
						"name":"103225390 ELOA; elongin A\tK15076 ELOA; elongin-A"
					},
					{
						"name":"103219279 UBAP2; ubiquitin associated protein 2\tK26545 UBAP2; ubiquitin-associated protein 2"
					},
					{
						"name":"103223929 UBAP2L; ubiquitin associated protein 2 like\tK26545 UBAP2; ubiquitin-associated protein 2"
					}
					]
				}
				]
			},
			{
				"name":"MMR (mismatch excision repair)",
				"children":[
				{
					"name":"Mismatch and loop recognition factors",
					"children":[
					{
						"name":"103220322 MSH2; mutS homolog 2\tK08735 MSH2; DNA mismatch repair protein MSH2"
					},
					{
						"name":"103223859 MSH3; mutS homolog 3\tK08736 MSH3; DNA mismatch repair protein MSH3"
					},
					{
						"name":"103220318 MSH6; mutS homolog 6\tK08737 MSH6; DNA mismatch repair protein MSH6"
					}
					]
				},
				{
					"name":"MutL homologs",
					"children":[
					{
						"name":"103217513 PMS1; PMS1 homolog 1, mismatch repair system component\tK10864 PMS1; DNA mismatch repair protein PMS1"
					},
					{
						"name":"103221085 MLH1; mutL homolog 1\tK08734 MLH1; DNA mismatch repair protein MLH1"
					},
					{
						"name":"103246803 PMS2; PMS1 homolog 2, mismatch repair system component\tK10858 PMS2; DNA mismatch repair protein PMS2"
					},
					{
						"name":"103229909 MLH3; mutL homolog 3\tK08739 MLH3; DNA mismatch repair protein MLH3"
					}
					]
				},
				{
					"name":"DNA polymerase delta complex",
					"children":[
					{
						"name":"103235079 transcription factor Spi-B\tK02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]"
					},
					{
						"name":"103226140 POLD2; DNA polymerase delta 2, accessory subunit\tK02328 POLD2; DNA polymerase delta subunit 2"
					},
					{
						"name":"103248038 POLD3; DNA polymerase delta 3, accessory subunit\tK03504 POLD3; DNA polymerase delta subunit 3"
					},
					{
						"name":"103218460 POLD4; DNA polymerase delta 4, accessory subunit\tK03505 POLD4; DNA polymerase delta subunit 4"
					}
					]
				},
				{
					"name":"RPA (replication factor A)",
					"children":[
					{
						"name":"103242545 RPA1; replication protein A1\tK07466 RFA1; replication factor A1"
					},
					{
						"name":"103225275 RPA2; replication protein A2\tK10739 RFA2; replication factor A2"
					},
					{
						"name":"103226491 RPA3; replication protein A3\tK10740 RPA3; replication factor A3"
					},
					{
						"name":"103232330 RPA4; replication protein A4\tK10741 RPA4; replication factor A4"
					}
					]
				},
				{
					"name":"RFC (replication factor C)",
					"children":[
					{
						"name":"103246204 RFC1; replication factor C subunit 1\tK10754 RFC1; replication factor C subunit 1"
					},
					{
						"name":"103241873 RFC4; replication factor C subunit 4\tK10755 RFC2_4; replication factor C subunit 2\/4"
					},
					{
						"name":"103246617 RFC2; replication factor C subunit 2\tK10755 RFC2_4; replication factor C subunit 2\/4"
					},
					{
						"name":"103214264 RFC3; replication factor C subunit 3\tK10756 RFC3_5; replication factor C subunit 3\/5"
					},
					{
						"name":"103239217 RFC5; replication factor C subunit 5\tK10756 RFC3_5; replication factor C subunit 3\/5"
					}
					]
				},
				{
					"name":"Other MMR factors",
					"children":[
					{
						"name":"103242170 proliferating cell nuclear antigen-like\tK04802 PCNA; proliferating cell nuclear antigen"
					},
					{
						"name":"103246929 PCNA; proliferating cell nuclear antigen\tK04802 PCNA; proliferating cell nuclear antigen"
					},
					{
						"name":"103230854 EXO1; exonuclease 1\tK10746 EXO1; exonuclease 1 [EC:3.1.-.-]"
					},
					{
						"name":"103237177 high mobility group protein B1\tK10802 HMGB1; high mobility group protein B1"
					},
					{
						"name":"103234960 LIG1; DNA ligase 1\tK10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]"
					},
					{
						"name":"103245722 WDR76; WD repeat domain 76\tK24755 WDR76; WD repeat-containing protein 76"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"DSBR (double strand breaks repair)",
			"children":[
			{
				"name":"HR (homologous recombination)",
				"children":[
				{
					"name":"MRN(MRX) complex",
					"children":[
					{
						"name":"103248255 MRE11; MRE11 homolog, double strand break repair nuclease\tK10865 MRE11; double-strand break repair protein MRE11"
					},
					{
						"name":"103244511 RAD50; RAD50 double strand break repair protein\tK10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]"
					},
					{
						"name":"103237098 NBN; nibrin\tK10867 NBN; nibrin"
					}
					]
				},
				{
					"name":"BRCA1-core complex",
					"children":[
					{
						"name":"103243855 BRCA1; BRCA1, DNA repair associated\tK10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]"
					},
					{
						"name":"103217790 BARD1; BRCA1 associated RING domain 1\tK10683 BARD1; BRCA1-associated RING domain protein 1"
					}
					]
				},
				{
					"name":"BRCA1-A complex",
					"children":[
					{
						"name":"103243855 BRCA1; BRCA1, DNA repair associated\tK10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]"
					},
					{
						"name":"103236689 FAM175A; family with sequence similarity 175 member A\tK20774 FAM175A; BRCA1-A complex subunit Abraxas"
					},
					{
						"name":"103245041 UIMC1; ubiquitin interaction motif containing 1\tK20775 UIMC1; BRCA1-A complex subunit RAP80"
					},
					{
						"name":"103234128 BABAM1; BRISC and BRCA1 A complex member 1\tK20776 BABAM; BRISC and BRCA1-A complex member 1"
					},
					{
						"name":"103220580 BRE; brain and reproductive organ-expressed (TNFRSF1A modulator)\tK12173 BRE; BRCA1-A complex subunit BRE"
					},
					{
						"name":"103232856 BRCC3; BRCA1\/BRCA2-containing complex subunit 3\tK11864 BRCC3; BRCA1\/BRCA2-containing complex subunit 3 [EC:3.4.19.-]"
					}
					]
				},
				{
					"name":"BRCA1-B complex",
					"children":[
					{
						"name":"103243855 BRCA1; BRCA1, DNA repair associated\tK10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]"
					},
					{
						"name":"103242813 BRIP1; BRCA1 interacting protein C-terminal helicase 1\tK15362 BRIP1; fanconi anemia group J protein [EC:5.6.2.3]"
					},
					{
						"name":"103241657 TOPBP1; topoisomerase (DNA) II binding protein 1\tK10728 TOPBP1; topoisomerase (DNA) II binding protein 1"
					}
					]
				},
				{
					"name":"BRCA1-C complex",
					"children":[
					{
						"name":"103243855 BRCA1; BRCA1, DNA repair associated\tK10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]"
					},
					{
						"name":"103222645 RBBP8; RB binding protein 8, endonuclease\tK20773 RBBP8; DNA endonuclease RBBP8 [EC:3.1.-.-]"
					},
					{
						"name":"103248255 MRE11; MRE11 homolog, double strand break repair nuclease\tK10865 MRE11; double-strand break repair protein MRE11"
					},
					{
						"name":"103244511 RAD50; RAD50 double strand break repair protein\tK10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]"
					},
					{
						"name":"103237098 NBN; nibrin\tK10867 NBN; nibrin"
					}
					]
				},
				{
					"name":"BRCA complex",
					"children":[
					{
						"name":"103243855 BRCA1; BRCA1, DNA repair associated\tK10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]"
					},
					{
						"name":"103214248 BRCA2; BRCA2, DNA repair associated\tK08775 BRCA2; breast cancer 2 susceptibility protein"
					},
					{
						"name":"103231873 PALB2; partner and localizer of BRCA2\tK10897 PALB2; partner and localizer of BRCA2"
					},
					{
						"name":"103245812 RAD51; RAD51 recombinase\tK04482 RAD51; DNA repair protein RAD51"
					}
					]
				},
				{
					"name":"RecA family proteins",
					"children":[
					{
						"name":"103245812 RAD51; RAD51 recombinase\tK04482 RAD51; DNA repair protein RAD51"
					},
					{
						"name":"103229218 RAD51B; RAD51 paralog B\tK10869 RAD51L1; RAD51-like protein 1"
					},
					{
						"name":"103242836 RAD51C; RAD51 paralog C\tK10870 RAD51L2; RAD51-like protein 2"
					},
					{
						"name":"103242727 RAD51D; RAD51 paralog D\tK10871 RAD51L3; RAD51-like protein 3"
					},
					{
						"name":"103227270 XRCC2; X-ray repair cross complementing 2\tK10879 XRCC2; DNA-repair protein XRCC2"
					},
					{
						"name":"103229765 XRCC3; X-ray repair cross complementing 3\tK10880 XRCC3; DNA-repair protein XRCC3"
					}
					]
				},
				{
					"name":"Rad52 family proteins",
					"children":[
					{
						"name":"103218365 RAD52; RAD52 homolog, DNA repair protein\tK10873 RAD52; DNA repair and recombination protein RAD52"
					},
					{
						"name":"103242753 RDM1; RAD52 motif containing 1\tK10874 RDM1; RAD52 motif-containing protein 1"
					}
					]
				},
				{
					"name":"Rad54 family proteins",
					"children":[
					{
						"name":"103224890 RAD54L; RAD54-like (S. cerevisiae)\tK10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]"
					},
					{
						"name":"103227693 RAD54L2; RAD54-like 2 (S. cerevisiae)\tK10876 RAD54L2; RAD54-like protein 2 [EC:5.6.2.-]"
					},
					{
						"name":"103237146 RAD54B; RAD54 homolog B (S. cerevisiae)\tK10877 RAD54B; DNA repair and recombination protein RAD54B [EC:5.6.2.-]"
					}
					]
				},
				{
					"name":"RecQ family DNA helicases",
					"children":[
					{
						"name":"103218735 RECQL; RecQ like helicase\tK10899 RECQL; ATP-dependent DNA helicase Q1 [EC:5.6.2.4]"
					},
					{
						"name":"103215588 WRN; Werner syndrome RecQ like helicase\tK10900 WRN; werner syndrome ATP-dependent helicase [EC:5.6.2.4]"
					},
					{
						"name":"103231188 BLM; Bloom syndrome RecQ like helicase\tK10901 BLM; bloom syndrome protein [EC:5.6.2.4]"
					},
					{
						"name":"103237633 RECQL4; RecQ like helicase 4\tK10730 RECQL4; ATP-dependent DNA helicase Q4 [EC:5.6.2.4]"
					},
					{
						"name":"103243039 RECQL5; RecQ like helicase 5\tK10902 RECQL5; ATP-dependent DNA helicase Q5 [EC:5.6.2.4]"
					}
					]
				},
				{
					"name":"Bloom's syndrome complex (BTR)",
					"children":[
					{
						"name":"103231188 BLM; Bloom syndrome RecQ like helicase\tK10901 BLM; bloom syndrome protein [EC:5.6.2.4]"
					},
					{
						"name":"103222938 TOP3B; topoisomerase (DNA) III beta\tK03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]"
					},
					{
						"name":"103242491 TOP3A; topoisomerase (DNA) III alpha\tK03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]"
					},
					{
						"name":"103219670 RMI1; RecQ mediated genome instability 1\tK10990 RMI1; RecQ-mediated genome instability protein 1"
					},
					{
						"name":"103228331 RMI2; RecQ mediated genome instability 2\tK15365 RMI2; RecQ-mediated genome instability protein 2"
					}
					]
				},
				{
					"name":"RPA (replication factor A)",
					"children":[
					{
						"name":"103242545 RPA1; replication protein A1\tK07466 RFA1; replication factor A1"
					},
					{
						"name":"103225275 RPA2; replication protein A2\tK10739 RFA2; replication factor A2"
					},
					{
						"name":"103226491 RPA3; replication protein A3\tK10740 RPA3; replication factor A3"
					},
					{
						"name":"103232330 RPA4; replication protein A4\tK10741 RPA4; replication factor A4"
					}
					]
				},
				{
					"name":"Protein phosphatase 4",
					"children":[
					{
						"name":"103230568 PPP4C; protein phosphatase 4 catalytic subunit\tK15423 PPP4C; serine\/threonine-protein phosphatase 4 catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"103222759 PPP4R1; protein phosphatase 4 regulatory subunit 1\tK15424 PPP4R1; serine\/threonine-protein phosphatase 4 regulatory subunit 1"
					},
					{
						"name":"103243620 putative serine\/threonine-protein phosphatase 4 regulatory subunit 1-like\tK15424 PPP4R1; serine\/threonine-protein phosphatase 4 regulatory subunit 1"
					},
					{
						"name":"103227906 PPP4R2; protein phosphatase 4 regulatory subunit 2\tK15425 PPP4R2; serine\/threonine-protein phosphatase 4 regulatory subunit 2"
					},
					{
						"name":"103220234 PPP4R3B; protein phosphatase 4 regulatory subunit 3B\tK17491 SMEK; protein phosphatase 4 regulatory subunit 3"
					},
					{
						"name":"103229557 PPP4R3A; protein phosphatase 4 regulatory subunit 3A\tK17491 SMEK; protein phosphatase 4 regulatory subunit 3"
					},
					{
						"name":"103231745 putative SMEK homolog 3\tK17491 SMEK; protein phosphatase 4 regulatory subunit 3"
					},
					{
						"name":"103229603 PPP4R4; protein phosphatase 4 regulatory subunit 4\tK15426 PPP4R4; serine\/threonine-protein phosphatase 4 regulatory subunit 4"
					}
					]
				},
				{
					"name":"AP-5 complex",
					"children":[
					{
						"name":"103226881 AP5B1; adaptor related protein complex 5 beta 1 subunit\tK19022 AP5B1; AP-5 complex subunit beta-1"
					},
					{
						"name":"103229066 AP5M1; adaptor related protein complex 5 mu 1 subunit\tK19023 AP5M1; AP-5 complex subunit mu-1"
					},
					{
						"name":"103247570 AP5S1; adaptor related protein complex 5 sigma 1 subunit\tK19024 AP5S1; AP-5 complex subunit sigma-1"
					},
					{
						"name":"103246849 AP5Z1; adaptor related protein complex 5 zeta 1 subunit\tK19025 AP5Z1; AP-5 complex subunit zeta-1"
					}
					]
				},
				{
					"name":"SMC5-SMC6 complex",
					"children":[
					{
						"name":"103219563 SMC5; structural maintenance of chromosomes 5\tK22803 SMC5; structural maintenance of chromosomes protein 5"
					},
					{
						"name":"103220752 SMC6; structural maintenance of chromosomes 6\tK22804 SMC6; structural maintenance of chromosomes protein 6"
					},
					{
						"name":"103220782 FAM84A; family with sequence similarity 84 member A\tK22805 FAM84A; protein FAM84A"
					},
					{
						"name":"103230090 NSMCE1; NSE1 homolog, SMC5-SMC6 complex component\tK22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27]"
					},
					{
						"name":"103237413 NSMCE2; NSE2\/MMS21 homolog, SMC5-SMC6 complex SUMO ligase\tK22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]"
					},
					{
						"name":"103245949 NSMCE3; NSE3 homolog, SMC5-SMC6 complex component\tK22823 NSMCE3; non-structural maintenance of chromosomes element 3"
					},
					{
						"name":"103216825 NSMCE4A; NSE4 homolog A, SMC5-SMC6 complex component\tK22825 NSMCE4; non-structural maintenance of chromosomes element 4"
					},
					{
						"name":"103224712 SLF1; SMC5-SMC6 complex localization factor 1\tK26126 SLF1; SMC5-SMC6 complex localization factor protein 1"
					},
					{
						"name":"103216399 SLF2; SMC5-SMC6 complex localization factor 2\tK26127 SLF2; SMC5-SMC6 complex localization factor protein 2"
					},
					{
						"name":"103245023 SIMC1; SUMO interacting motifs containing 1\tK28408 SIMC1; SUMO-interacting motif-containing protein 1"
					}
					]
				},
				{
					"name":"Other HR factors",
					"children":[
					{
						"name":"103242936 EME1; essential meiotic structure-specific endonuclease 1\tK10882 EME1; crossover junction endonuclease EME1 [EC:3.1.22.-]"
					},
					{
						"name":"103226307 EME2; essential meiotic structure-specific endonuclease subunit 2\tK10883 EME2; crossover junction endonuclease EME2"
					},
					{
						"name":"103229241 EXD2; exonuclease 3'-5' domain containing 2\tK20777 EXD2; exonuclease 3'-5' domain-containing protein 2 [EC:3.1.11.1]"
					},
					{
						"name":"103243152 crossover junction endonuclease MUS81\tK08991 MUS81; crossover junction endonuclease MUS81 [EC:3.1.22.-]"
					},
					{
						"name":"103226516 SEM1; SEM1, 26S proteasome complex subunit\tK10881 SHFM1; 26 proteasome complex subunit DSS1"
					},
					{
						"name":"103239805 SWI5; SWI5 homologous recombination repair protein\tK10991 SWI5; DNA repair protein Swi5\/Sae3"
					},
					{
						"name":"103216469 SFR1; SWI5 dependent homologous recombination repair protein 1\tK10992 SFR1; Swi5-dependent recombination DNA repair protein 1"
					},
					{
						"name":"103230455 SLX1A; SLX1 homolog A, structure-specific endonuclease subunit\tK15078 SLX1; structure-specific endonuclease subunit SLX1 [EC:3.6.1.-]"
					},
					{
						"name":"103227532 SLX4; SLX4 structure-specific endonuclease subunit\tK10484 BTBD12; structure-specific endonuclease subunit SLX4 (BTB\/POZ domain-containing protein 12)"
					},
					{
						"name":"103220753 GEN1; GEN1, Holliday junction 5' flap endonuclease\tK15338 GEN1; holliday junction resolvase GEN1\/YEN1 [EC:3.1.-.-]"
					},
					{
						"name":"103246093 SPG11; spastic paraplegia 11 (autosomal recessive)\tK19026 SPG11; spatacsin"
					},
					{
						"name":"103229216 ZFYVE26; zinc finger FYVE-type containing 26\tK19027 ZFYVE26; zinc finger FYVE domain-containing protein 26"
					},
					{
						"name":"103218421 RAD51AP1; RAD51 associated protein 1\tK20778 RAD51AP1; RAD51-associated protein 1"
					},
					{
						"name":"103230218 NUCKS1; nuclear casein kinase and cyclin dependent kinase substrate 1\tK28888 NUCKS1; nuclear ubiquitous casein and cyclin-dependent kinase substrate 1"
					},
					{
						"name":"103228439 mortality factor 4-like protein 1\tK11339 MORF4L1; mortality factor 4-like protein 1"
					},
					{
						"name":"103245243 MORF4L1; mortality factor 4 like 1\tK11339 MORF4L1; mortality factor 4-like protein 1"
					},
					{
						"name":"103216548 SAMHD1; SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1\tK22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-]"
					},
					{
						"name":"103226077 FIGNL1; fidgetin like 1\tK22766 FIGNL1; fidgetin-like protein 1 [EC:5.6.2.-]"
					},
					{
						"name":"103236756 SPIDR; scaffolding protein involved in DNA repair\tK22806 SPIDR; DNA repair-scaffolding protein"
					},
					{
						"name":"103237425 FAM84B; family with sequence similarity 84 member B\tK22810 FAM84B; protein FAM84B"
					},
					{
						"name":"103246959 BRAT1; BRCA1 associated ATM activator 1\tK23112 BRAT1; BRCA1-associated ATM activator 1"
					},
					{
						"name":"103219802 C2H21orf2; chromosome 2 C21orf2 homolog\tK23456 CFAP410; cilla- and flagella-associated protein"
					},
					{
						"name":"103233701 hepatoma-derived growth factor-related protein 2\tK25065 HDGFL2; hepatoma-derived growth factor-related protein 2"
					},
					{
						"name":"103242454 ZSWIM7; zinc finger SWIM-type containing 7\tK25770 ZSWIM7; zinc finger SWIM domain-containing protein 7"
					},
					{
						"name":"103233929 SWSAP1; SWIM-type zinc finger 7 associated protein 1\tK25771 SWSAP1; ATPase SWSAP1"
					},
					{
						"name":"103248079 EMSY; EMSY, BRCA2 interacting transcriptional repressor\tK25790 EMSY; BRCA2-interacting transcriptional repressor EMSY"
					},
					{
						"name":"103219571 HSF2BP; heat shock transcription factor 2 binding protein\tK25791 HSF2BP; heat shock factor 2-binding protein"
					},
					{
						"name":"103240697 MMS22L; MMS22 like, DNA repair protein\tK26125 MMS22L; protein MMS22-like"
					},
					{
						"name":"103237627 TONSL; tonsoku-like, DNA repair protein\tK09257 NFKBIL2; NF-kappa-B inhibitor-like protein 2"
					},
					{
						"name":"103246348 BOD1L1; biorientation of chromosomes in cell division 1 like 1\tK27262 BOD1L1; biorientation of chromosomes in cell division protein 1-like 1"
					},
					{
						"name":"103238955 PARPBP; PARP1 binding protein\tK27412 PARPBP; PCNA-interacting partner"
					},
					{
						"name":"103243333 C16H17orf53; chromosome 16 open reading frame, human C17orf53\tK27803 HROB; homologous recombination OB-fold protein"
					},
					{
						"name":"103246811 MCM8; minichromosome maintenance 8 homologous recombination repair factor\tK10737 MCM8; DNA helicase MCM8 [EC:5.6.2.4]"
					},
					{
						"name":"103240484 MCM9; minichromosome maintenance 9 homologous recombination repair factor\tK10738 MCM9; DNA helicase MCM9 [EC:5.6.2.4]"
					},
					{
						"name":"103234726 HNRNPUL1; heterogeneous nuclear ribonucleoprotein U like 1\tK15047 HNRNPUL1; heterogeneous nuclear ribonucleoprotein U-like protein 1"
					},
					{
						"name":"103233912 HNRNPUL2; heterogeneous nuclear ribonucleoprotein U like 2\tK28611 HNRNPUL2; heterogeneous nuclear ribonucleoprotein U-like protein 2"
					},
					{
						"name":"103245111 MRNIP; MRN complex interacting protein\tK28623 MRNIP; MRN complex-interacting protein"
					},
					{
						"name":"103232445 CXHXorf57; chromosome X open reading frame, human CXorf57\tK29002 RADX; RPA-related protein RADX"
					},
					{
						"name":"103228637 RBM6; RNA binding motif protein 6\tK29038 RBM6; RNA-binding protein 6"
					}
					]
				}
				]
			},
			{
				"name":"NHEJ (non-homologous end-joining)",
				"children":[
				{
					"name":"DNA-PK complex",
					"children":[
					{
						"name":"103216276 X-ray repair cross-complementing protein 6-like\tK10884 XRCC6; ATP-dependent DNA helicase 2 subunit 1"
					},
					{
						"name":"103223389 XRCC6; X-ray repair cross complementing 6\tK10884 XRCC6; ATP-dependent DNA helicase 2 subunit 1"
					},
					{
						"name":"103217811 XRCC5; X-ray repair cross complementing 5\tK10885 XRCC5; ATP-dependent DNA helicase 2 subunit 2"
					},
					{
						"name":"103236758 PRKDC; protein kinase, DNA-activated, catalytic polypeptide\tK06642 PRKDC; DNA-dependent protein kinase catalytic subunit [EC:2.7.11.1]"
					}
					]
				},
				{
					"name":"MRX complex",
					"children":[
					{
						"name":"103248255 MRE11; MRE11 homolog, double strand break repair nuclease\tK10865 MRE11; double-strand break repair protein MRE11"
					},
					{
						"name":"103244511 RAD50; RAD50 double strand break repair protein\tK10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]"
					}
					]
				},
				{
					"name":"DNA Ligase 4 complex",
					"children":[
					{
						"name":"103214778 LIG4; DNA ligase 4\tK10777 LIG4; DNA ligase 4 [EC:6.5.1.1]"
					},
					{
						"name":"103224082 XRCC4; X-ray repair cross complementing 4\tK10886 XRCC4; DNA-repair protein XRCC4"
					},
					{
						"name":"103217895 NHEJ1; non-homologous end joining factor 1\tK10980 NHEJ1; non-homologous end-joining factor 1"
					}
					]
				},
				{
					"name":"X-family DNA polymerases",
					"children":[
					{
						"name":"103216413 POLL; DNA polymerase lambda\tK03512 POLL; DNA polymerase lambda [EC:2.7.7.7 4.2.99.-]"
					},
					{
						"name":"103226146 POLM; DNA polymerase mu\tK03513 POLM; DNA polymerase mu [EC:2.7.7.7]"
					},
					{
						"name":"103216324 DNTT; DNA nucleotidylexotransferase\tK00977 DNTT; DNA nucleotidylexotransferase [EC:2.7.7.31]"
					},
					{
						"name":"103215689 POLB; DNA polymerase beta\tK02330 POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-]"
					}
					]
				},
				{
					"name":"Other NHEJ factors",
					"children":[
					{
						"name":"103219297 APTX; aprataxin\tK10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]"
					},
					{
						"name":"103220122 APLF; aprataxin and PNKP like factor\tK13295 APLF; aprataxin and PNK-like factor [EC:3.1.-.-]"
					},
					{
						"name":"103238145 DCLRE1C; DNA cross-link repair 1C\tK10887 DCLRE1C; DNA cross-link repair 1C protein [EC:3.1.-.-]"
					},
					{
						"name":"103222049 TDP2; tyrosyl-DNA phosphodiesterase 2\tK19619 TDP2; tyrosyl-DNA phosphodiesterase 2 [EC:3.1.4.-]"
					},
					{
						"name":"103222694 SMCHD1; structural maintenance of chromosomes flexible hinge domain containing 1\tK23113 SMCHD1; structural maintenance of chromosomes flexible hinge domain-containing protein 1"
					},
					{
						"name":"103232442 MUM1L1; MUM1 like 1\tK23386 PWWP3; PWWP domain-containing DNA repair factor 3"
					},
					{
						"name":"103233604 PWWP domain-containing protein MUM1\tK23386 PWWP3; PWWP domain-containing DNA repair factor 3"
					},
					{
						"name":"103239595 C12H9orf142; chromosome 12 open reading frame, human C9orf142\tK25772 PAXX; protein PAXX"
					},
					{
						"name":"103226941 C21H7orf49; chromosome 21 open reading frame, human C7orf49\tK26155 CYREN; cell cycle regulator of non-homologous end joining"
					},
					{
						"name":"103225614 JMJD8; jumonji domain containing 8\tK25792 JMJD8; jumonji domain-containing protein 8"
					},
					{
						"name":"103246842 C2H20orf196; chromosome 2 open reading frame, human C20orf196\tK26128 SHLD1; shieldin complex subunit 1"
					},
					{
						"name":"103215861 FAM35A; family with sequence similarity 35 member A\tK26129 SHLD2; shieldin complex subunit 2"
					},
					{
						"name":"103222379 uncharacterized LOC103222379\tK26130 SHLD3; shieldin complex subunit 3"
					},
					{
						"name":"103246162 BEND4; BEN domain containing 4\tK27845 BEND4; BEN domain-containing protein 4"
					},
					{
						"name":"103218463 IFFO1; intermediate filament family orphan 1\tK28738 IFFO; non-homologous end joining factor IFFO"
					},
					{
						"name":"103225486 IFFO2; intermediate filament family orphan 2\tK28738 IFFO; non-homologous end joining factor IFFO"
					}
					]
				}
				]
			},
			{
				"name":"FA (Fanconi anemia) pathway",
				"children":[
				{
					"name":"FA core complex",
					"children":[
					{
						"name":"103233491 FANCA; Fanconi anemia complementation group A\tK10888 FANCA; fanconi anemia group A protein"
					},
					{
						"name":"103231629 FANCB; Fanconi anemia complementation group B\tK10889 FANCB; fanconi anemia group B protein"
					},
					{
						"name":"103219828 FANCC; Fanconi anemia complementation group C\tK10890 FANCC; fanconi anemia group C protein"
					},
					{
						"name":"103221613 FANCE; Fanconi anemia complementation group E\tK10892 FANCE; fanconi anemia group E protein"
					},
					{
						"name":"103238775 FANCF; Fanconi anemia complementation group F\tK10893 FANCF; fanconi anemia group F protein"
					},
					{
						"name":"103219234 FANCG; Fanconi anemia complementation group G\tK10894 FANCG; fanconi anemia group G protein"
					},
					{
						"name":"103220221 FANCL; Fanconi anemia complementation group L\tK10606 FANCL; E3 ubiquitin-protein ligase FANCL [EC:2.3.2.27]"
					},
					{
						"name":"103228909 FANCM; Fanconi anemia complementation group M\tK10896 FANCM; fanconi anemia group M protein"
					},
					{
						"name":"103234452 FAAP24; Fanconi anemia core complex associated protein 24\tK10898 FAAP24; fanconi anemia-associated protein"
					},
					{
						"name":"103243721 Fanconi anemia-associated protein of 100 kDa\tK10993 FAAP100; fanconi anemia core complex 100 kDa subunit"
					},
					{
						"name":"103243722 Fanconi anemia-associated protein of 100 kDa-like\tK10993 FAAP100; fanconi anemia core complex 100 kDa subunit"
					}
					]
				},
				{
					"name":"FA core complex binding factors",
					"children":[
					{
						"name":"103241935 HES1; hes family bHLH transcription factor 1\tK06054 HES1; hairy and enhancer of split 1"
					},
					{
						"name":"103225627 centromere protein S\tK11511 APITD1; centromere protein S"
					},
					{
						"name":"103243746 CENPX; centromere protein X\tK15360 STRA13; centromere protein X"
					},
					{
						"name":"103230310 UBE2T; ubiquitin conjugating enzyme E2 T\tK13960 UBE2T; ubiquitin-conjugating enzyme E2 T [EC:2.3.2.23]"
					}
					]
				},
				{
					"name":"Bloom's syndrome complex (BTR)",
					"children":[
					{
						"name":"103231188 BLM; Bloom syndrome RecQ like helicase\tK10901 BLM; bloom syndrome protein [EC:5.6.2.4]"
					},
					{
						"name":"103222938 TOP3B; topoisomerase (DNA) III beta\tK03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]"
					},
					{
						"name":"103242491 TOP3A; topoisomerase (DNA) III alpha\tK03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]"
					},
					{
						"name":"103219670 RMI1; RecQ mediated genome instability 1\tK10990 RMI1; RecQ-mediated genome instability protein 1"
					},
					{
						"name":"103228331 RMI2; RecQ mediated genome instability 2\tK15365 RMI2; RecQ-mediated genome instability protein 2"
					}
					]
				},
				{
					"name":"FANCD2-I complex",
					"children":[
					{
						"name":"103228652 FANCD2; Fanconi anemia complementation group D2\tK10891 FANCD2; fanconi anemia group D2 protein"
					},
					{
						"name":"103231150 FANCI; Fanconi anemia complementation group I\tK10895 FANCI; fanconi anemia group I protein"
					}
					]
				},
				{
					"name":"Downstream FA components",
					"children":[
					{
						"name":"103243855 BRCA1; BRCA1, DNA repair associated\tK10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]"
					},
					{
						"name":"103214248 BRCA2; BRCA2, DNA repair associated\tK08775 BRCA2; breast cancer 2 susceptibility protein"
					},
					{
						"name":"103242813 BRIP1; BRCA1 interacting protein C-terminal helicase 1\tK15362 BRIP1; fanconi anemia group J protein [EC:5.6.2.3]"
					},
					{
						"name":"103231873 PALB2; partner and localizer of BRCA2\tK10897 PALB2; partner and localizer of BRCA2"
					}
					]
				},
				{
					"name":"Other FA pathway factors",
					"children":[
					{
						"name":"103245944 FAN1; FANCD2 and FANCI associated nuclease 1\tK15363 FAN1; fanconi-associated nuclease 1 [EC:3.1.21.- 3.1.4.1]"
					},
					{
						"name":"103245812 RAD51; RAD51 recombinase\tK04482 RAD51; DNA repair protein RAD51"
					},
					{
						"name":"103242836 RAD51C; RAD51 paralog C\tK10870 RAD51L2; RAD51-like protein 2"
					},
					{
						"name":"103226141 TELO2; telomere maintenance 2\tK11137 TELO2; telomere length regulation protein"
					},
					{
						"name":"103224705 USP1; ubiquitin specific peptidase 1\tK11832 USP1; ubiquitin carboxyl-terminal hydrolase 1 [EC:3.4.19.12]"
					},
					{
						"name":"103221048 WDR48; WD repeat domain 48\tK15361 WDR48; WD repeat-containing protein 48"
					}
					]
				}
				]
			},
			{
				"name":"Other DSBR factors",
				"children":[
				{
					"name":"Protein phosphatase 6",
					"children":[
					{
						"name":"103239872 PPP6C; protein phosphatase 6 catalytic subunit\tK15498 PPP6C; serine\/threonine-protein phosphatase 6 catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"103235564 PPP6R1; protein phosphatase 6 regulatory subunit 1\tK15499 PPP6R1; serine\/threonine-protein phosphatase 6 regulatory subunit 1"
					},
					{
						"name":"103223559 PPP6R2; protein phosphatase 6 regulatory subunit 2\tK15500 PPP6R2; serine\/threonine-protein phosphatase 6 regulatory subunit 2"
					},
					{
						"name":"103248840 PPP6R3; protein phosphatase 6 regulatory subunit 3\tK15501 PPP6R3; serine\/threonine-protein phosphatase 6 regulatory subunit 3"
					},
					{
						"name":"103241720 ANKRD28; ankyrin repeat domain 28\tK15502 ANKRD28; serine\/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A"
					},
					{
						"name":"103217578 ANKRD44; ankyrin repeat domain 44\tK15503 ANKRD44; serine\/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B"
					},
					{
						"name":"103238514 ANKRD52; ankyrin repeat domain 52\tK15504 ANKRD52; serine\/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C"
					}
					]
				},
				{
					"name":"Ubiquitin ligases",
					"children":[
					{
						"name":"103221569 RNF8; ring finger protein 8\tK10667 RNF8; E3 ubiquitin-protein ligase RNF8 [EC:2.3.2.27]"
					},
					{
						"name":"103241996 RNF168; ring finger protein 168\tK20779 RNF168; E3 ubiquitin-protein ligase RNF168 [EC:2.3.2.31]"
					},
					{
						"name":"103248045 RNF169; ring finger protein 169\tK20805 RNF169; E3 ubiquitin-protein ligase RNF169 [EC:2.3.2.31]"
					},
					{
						"name":"103245991 HERC2; HECT and RLD domain containing E3 ubiquitin protein ligase 2\tK10595 HERC2; E3 ubiquitin-protein ligase HERC2 [EC:2.3.2.26]"
					}
					]
				},
				{
					"name":"Others",
					"children":[
					{
						"name":"103242321 WRAP53; WD repeat containing antisense to TP53\tK23314 WRAP53; telomerase Cajal body protein 1"
					},
					{
						"name":"103239571 TPRN; taperin\tK24164 TPRN; taperin"
					},
					{
						"name":"103246948 ZCWPW1; zinc finger CW-type and PWWP domain containing 1\tK24688 ZCWPW1; zinc finger CW-type PWWP domain protein 1"
					},
					{
						"name":"103215150 WDR70; WD repeat domain 70\tK24752 WDR70; WD repeat-containing protein 70"
					},
					{
						"name":"103245722 WDR76; WD repeat domain 76\tK24755 WDR76; WD repeat-containing protein 76"
					},
					{
						"name":"103228077 HMCES; 5-hydroxymethylcytosine (hmC) binding, ES cell-specific\tK28434 HMCES; abasic site processing protein HMCES"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"TLS (translesion DNA synthesis) factors",
			"children":[
			{
				"name":"Y-family DNA polymerases",
				"children":[
				{
					"name":"103221454 POLH; DNA polymerase eta\tK03509 POLH; DNA polymerase eta [EC:2.7.7.7]"
				},
				{
					"name":"103222404 POLI; DNA polymerase iota\tK03510 POLI; DNA polymerase iota [EC:2.7.7.7]"
				},
				{
					"name":"103223255 POLK; DNA polymerase kappa\tK03511 POLK; DNA polymerase kappa [EC:2.7.7.7]"
				},
				{
					"name":"103241114 REV1; REV1, DNA directed polymerase\tK03515 REV1; DNA repair protein REV1 [EC:2.7.7.-]"
				}
				]
			},
			{
				"name":"B-family DNA polymerases",
				"children":[
				{
					"name":"103240579 REV3L; REV3 like, DNA directed polymerase zeta catalytic subunit\tK02350 REV3L; DNA polymerase zeta [EC:2.7.7.7]"
				}
				]
			},
			{
				"name":"A-family DNA polymerase",
				"children":[
				{
					"name":"103246469 POLN; DNA polymerase nu\tK16618 POLN; DNA polymerase nu [EC:2.7.7.7]"
				}
				]
			},
			{
				"name":"Rad6 epistasis group",
				"children":[
				{
					"name":"103247335 UBE2A; ubiquitin conjugating enzyme E2 A\tK10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]"
				},
				{
					"name":"103244546 UBE2B; ubiquitin conjugating enzyme E2 B\tK10574 UBE2B; ubiquitin-conjugating enzyme E2 B [EC:2.3.2.23]"
				},
				{
					"name":"103227963 RAD18; RAD18, E3 ubiquitin protein ligase\tK10627 RAD18; E3 ubiquitin-protein ligase RAD18 [EC:2.3.2.27]"
				},
				{
					"name":"103241505 HLTF; helicase like transcription factor\tK15711 SMARCA3; SWI\/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A3 [EC:5.6.2. 2.3.2.27]"
				},
				{
					"name":"103218272 ubiquitin-conjugating enzyme E2 variant 1\tK10704 UBE2V; ubiquitin-conjugating enzyme E2 variant"
				},
				{
					"name":"103222584 ubiquitin-conjugating enzyme E2 variant 2\tK10704 UBE2V; ubiquitin-conjugating enzyme E2 variant"
				},
				{
					"name":"103236760 UBE2V2; ubiquitin conjugating enzyme E2 V2\tK10704 UBE2V; ubiquitin-conjugating enzyme E2 variant"
				},
				{
					"name":"103244472 UBE2V1; ubiquitin conjugating enzyme E2 V1\tK10704 UBE2V; ubiquitin-conjugating enzyme E2 variant"
				},
				{
					"name":"103232698 ubiquitin-conjugating enzyme E2 N-like\tK10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]"
				},
				{
					"name":"103233100 ubiquitin-conjugating enzyme E2 N-like\tK10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]"
				},
				{
					"name":"103233237 ubiquitin-conjugating enzyme E2 N-like\tK10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]"
				},
				{
					"name":"103236528 ubiquitin-conjugating enzyme E2 N-like\tK10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]"
				},
				{
					"name":"103238868 UBE2N; ubiquitin conjugating enzyme E2 N\tK10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]"
				}
				]
			},
			{
				"name":"Other TLS factors",
				"children":[
				{
					"name":"103242170 proliferating cell nuclear antigen-like\tK04802 PCNA; proliferating cell nuclear antigen"
				},
				{
					"name":"103246929 PCNA; proliferating cell nuclear antigen\tK04802 PCNA; proliferating cell nuclear antigen"
				},
				{
					"name":"103245496 PCLAF; PCNA clamp associated factor\tK28763 PCLAF; PCNA-associated factor"
				},
				{
					"name":"103238955 PARPBP; PARP1 binding protein\tK27412 PARPBP; PCNA-interacting partner"
				},
				{
					"name":"103230754 SPRTN; SprT-like N-terminal domain\tK24051 SPRTN; SprT-like domain-contaning protein Spartan"
				},
				{
					"name":"103232165 GCNA; germ cell nuclear acidic peptidase\tK26957 GCNA; germ cell nuclear acidic protein"
				},
				{
					"name":"103243904 DPPA5; developmental pluripotency associated 5\tK28975 DPPA5; developmental pluripotency-associated protein 5"
				}
				]
			}
			]
		},
		{
			"name":"Check point factors",
			"children":[
			{
				"name":"Rad9-Hus1-Rad1 complex",
				"children":[
				{
					"name":"103218667 RAD9A; RAD9 checkpoint clamp component A\tK10994 RAD9A; cell cycle checkpoint control protein RAD9A [EC:3.1.11.2]"
				},
				{
					"name":"103239112 RAD9B; RAD9 checkpoint clamp component B\tK10995 RAD9B; cell cycle checkpoint control protein RAD9B"
				},
				{
					"name":"103226096 HUS1; HUS1 checkpoint clamp component\tK10903 HUS1; HUS1 checkpoint protein"
				},
				{
					"name":"103222315 HUS1B; HUS1 checkpoint clamp component B\tK10996 HUS1B; checkpoint protein HUS1B"
				},
				{
					"name":"103215115 RAD1; RAD1 checkpoint DNA exonuclease\tK02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]"
				}
				]
			},
			{
				"name":"HRAD17(Rad24)-RFC complex",
				"children":[
				{
					"name":"103222718 RAD17; RAD17 checkpoint clamp loader component\tK06662 HRAD17; cell cycle checkpoint protein"
				},
				{
					"name":"103241873 RFC4; replication factor C subunit 4\tK10755 RFC2_4; replication factor C subunit 2\/4"
				},
				{
					"name":"103246617 RFC2; replication factor C subunit 2\tK10755 RFC2_4; replication factor C subunit 2\/4"
				},
				{
					"name":"103214264 RFC3; replication factor C subunit 3\tK10756 RFC3_5; replication factor C subunit 3\/5"
				},
				{
					"name":"103239217 RFC5; replication factor C subunit 5\tK10756 RFC3_5; replication factor C subunit 3\/5"
				}
				]
			},
			{
				"name":"Rad17-Mec3-Ddc1 complex",
				"children":[
				{
					"name":"103215115 RAD1; RAD1 checkpoint DNA exonuclease\tK02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]"
				}
				]
			},
			{
				"name":"FPC (fork protection complex)",
				"children":[
				{
					"name":"103238528 TIMELESS; timeless circadian clock\tK10997 TIMELESS; replication fork protection complex subunit TIMELESS\/Tof1\/Swi1"
				},
				{
					"name":"103245452 TIPIN; TIMELESS interacting protein\tK10998 TIPIN; replication fork protection complex subunit TIPIN\/Csm3\/Swi3"
				},
				{
					"name":"103225127 CLSPN; claspin\tK25773 CLSPN; claspin"
				}
				]
			},
			{
				"name":"Triple T complex",
				"children":[
				{
					"name":"103226141 TELO2; telomere maintenance 2\tK11137 TELO2; telomere length regulation protein"
				},
				{
					"name":"103246312 TTI1; TELO2 interacting protein 1\tK20403 TTI1; TELO2-interacting protein 1"
				},
				{
					"name":"103215600 TTI2; TELO2 interacting protein 2\tK23115 TTI2; TELO2-interacting protein 2"
				}
				]
			},
			{
				"name":"BAG6-UBL4A-GET4 complex",
				"children":[
				{
					"name":"103224260 UBL4B; ubiquitin like 4B\tK23388 UBL4; ubiquitin-like protein 4"
				},
				{
					"name":"103232828 UBL4A; ubiquitin like 4A\tK23388 UBL4; ubiquitin-like protein 4"
				},
				{
					"name":"103246895 GET4; golgi to ER traffic protein 4\tK23387 GET4; golgi to ER traffic protein 4"
				}
				]
			},
			{
				"name":"SOSS complex",
				"children":[
				{
					"name":"103223949 INTS3; integrator complex subunit 3\tK13140 INTS3; integrator complex subunit 3 (SOSS complex subunit A)"
				},
				{
					"name":"103217540 NABP1; nucleic acid binding protein 1\tK28889 NABP; SOSS complex subunit B"
				},
				{
					"name":"103238517 NABP2; nucleic acid binding protein 2\tK28889 NABP; SOSS complex subunit B"
				},
				{
					"name":"103219006 INIP; INTS3 and NABP interacting protein\tK28890 INIP; SOSS complex subunit C"
				}
				]
			},
			{
				"name":"Other check point factors",
				"children":[
				{
					"name":"103241557 ATR; ATR serine\/threonine kinase\tK06640 ATR; serine\/threonine-protein kinase ATR [EC:2.7.11.1]"
				},
				{
					"name":"103227590 ATRIP; ATR interacting protein\tK10905 ATRIP; ATR interacting protein"
				},
				{
					"name":"103220137 ETAA1; Ewing tumor associated antigen 1\tK28856 ETAA1; Ewing's tumor-associated antigen 1"
				},
				{
					"name":"103248401 ATM; ATM serine\/threonine kinase\tK04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]"
				},
				{
					"name":"103242323 TP53; tumor protein p53\tK04451 TP53; tumor protein p53"
				},
				{
					"name":"103248769 CHEK1; checkpoint kinase 1\tK02216 CHEK1; serine\/threonine-protein kinase CHEK1 [EC:2.7.11.1]"
				},
				{
					"name":"103223122 CHEK2; checkpoint kinase 2\tK06641 CHEK2; serine\/threonine-protein kinase CHEK2 [EC:2.7.11.1]"
				},
				{
					"name":"103228635 CDC25A; cell division cycle 25A\tK06645 CDC25A; M-phase inducer phosphatase 1 [EC:3.1.3.48]"
				},
				{
					"name":"103247543 CDC25B; cell division cycle 25B\tK05866 CDC25B; M-phase inducer phosphatase 2 [EC:3.1.3.48]"
				},
				{
					"name":"103244613 CDC25C; cell division cycle 25C\tK05867 CDC25C; M-phase inducer phosphatase 3 [EC:3.1.3.48]"
				},
				{
					"name":"103220843 YWHAQ; tyrosine 3-monooxygenase\/tryptophan 5-monooxygenase activation protein theta\tK16197 YWHAB_Q_Z; 14-3-3 protein beta\/theta\/zeta"
				},
				{
					"name":"103237221 YWHAZ; tyrosine 3-monooxygenase\/tryptophan 5-monooxygenase activation protein zeta\tK16197 YWHAB_Q_Z; 14-3-3 protein beta\/theta\/zeta"
				},
				{
					"name":"103245470 YWHAB; tyrosine 3-monooxygenase\/tryptophan 5-monooxygenase activation protein beta\tK16197 YWHAB_Q_Z; 14-3-3 protein beta\/theta\/zeta"
				},
				{
					"name":"103223201 YWHAH; tyrosine 3-monooxygenase\/tryptophan 5-monooxygenase activation protein eta\tK16198 YWHAG_H; 14-3-3 protein gamma\/eta"
				},
				{
					"name":"103246662 YWHAG; tyrosine 3-monooxygenase\/tryptophan 5-monooxygenase activation protein gamma\tK16198 YWHAG_H; 14-3-3 protein gamma\/eta"
				},
				{
					"name":"103242121 YWHAE; tyrosine 3-monooxygenase\/tryptophan 5-monooxygenase activation protein epsilon\tK06630 YWHAE; 14-3-3 protein epsilon"
				},
				{
					"name":"103238916 NAV2; neuron navigator 2\tK19483 NAV2; neuron navigator 2 [EC:5.6.2.4]"
				},
				{
					"name":"103227031 WEE2; WEE1 homolog 2\tK06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]"
				},
				{
					"name":"103240451 WEE1; WEE1 G2 checkpoint kinase\tK06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]"
				},
				{
					"name":"103242342 PER1; period circadian clock 1\tK21944 PER1; period circadian protein 1"
				},
				{
					"name":"103218182 PER2; period circadian clock 2\tK02633 PER2; period circadian protein 2"
				},
				{
					"name":"103225668 PER3; period circadian clock 3\tK21945 PER3; period circadian protein 3"
				},
				{
					"name":"103221821 MDC1; mediator of DNA damage checkpoint 1\tK20780 MDC1; mediator of DNA damage checkpoint protein 1"
				},
				{
					"name":"103247415 plastin-3-like\tK17336 PLS3; plastin-3"
				},
				{
					"name":"103231135 AEN; apoptosis enhancing nuclease\tK18340 AEN; apoptosis-enhancing nuclease [EC:3.1.-.-]"
				},
				{
					"name":"103224928 PLK3; polo like kinase 3\tK08862 PLK3; polo-like kinase 3 [EC:2.7.11.21]"
				},
				{
					"name":"103233613 PLK5; polo like kinase 5\tK19596 PLK5; inactive serine\/threonine-protein kinase PLK5"
				},
				{
					"name":"103214473 NEK5; NIMA related kinase 5\tK08857 NEK1_4_5; serine\/threonine-protein kinase Nek1\/4\/5 [EC:2.7.11.1]"
				},
				{
					"name":"103227744 NEK4; NIMA related kinase 4\tK08857 NEK1_4_5; serine\/threonine-protein kinase Nek1\/4\/5 [EC:2.7.11.1]"
				},
				{
					"name":"103236516 NEK1; NIMA related kinase 1\tK08857 NEK1_4_5; serine\/threonine-protein kinase Nek1\/4\/5 [EC:2.7.11.1]"
				},
				{
					"name":"103241786 NEK10; NIMA related kinase 10\tK20879 NEK10; serine\/threonine-protein kinase Nek10 [EC:2.7.11.1]"
				},
				{
					"name":"103241692 NEK11; NIMA related kinase 11\tK20880 NEK11; serine\/threonine-protein kinase Nek11 [EC:2.7.11.1]"
				},
				{
					"name":"103216712 DONSON; downstream neighbor of SON\tK22422 DONSON; protein downstream neighbor of Son"
				},
				{
					"name":"103219533 KANK1; KN motif and ankyrin repeat domains 1\tK22808 KANK; KN motif and ankyrin repeat domain-containing protein"
				},
				{
					"name":"103224706 KANK4; KN motif and ankyrin repeat domains 4\tK22808 KANK; KN motif and ankyrin repeat domain-containing protein"
				},
				{
					"name":"103233837 KANK3; KN motif and ankyrin repeat domains 3\tK22808 KANK; KN motif and ankyrin repeat domain-containing protein"
				},
				{
					"name":"103233918 KANK2; KN motif and ankyrin repeat domains 2\tK22808 KANK; KN motif and ankyrin repeat domain-containing protein"
				},
				{
					"name":"103216209 KLLN; killin, p53-regulated DNA replication inhibitor\tK23389 KLLN; killin"
				},
				{
					"name":"103242730 SLFN11; schlafen family member 11\tK24458 SLFN11; schlafen family member 11 [EC:3.6.-.-]"
				},
				{
					"name":"103237049 CHMP4C; charged multivesicular body protein 4C\tK24782 CHMP4C; charged multivesicular body protein 4C"
				},
				{
					"name":"103233218 VPS4A; vacuolar protein sorting 4 homolog A\tK12196 VPS4; vacuolar protein-sorting-associated protein 4"
				},
				{
					"name":"103244163 VPS4B; vacuolar protein sorting 4 homolog B\tK12196 VPS4; vacuolar protein-sorting-associated protein 4"
				},
				{
					"name":"103245818 zinc finger FYVE domain-containing protein 19-like\tK24778 ZFYVE19; abscission\/NoCut checkpoint regulator"
				},
				{
					"name":"103229997 SDE2; SDE2 telomere maintenance homolog\tK25059 SDE2; replication stress response regulator SDE2"
				},
				{
					"name":"103241357 KRCC1; lysine rich coiled-coil 1\tK29003 KRCC1; lysine-rich coiled-coil protein 1"
				},
				{
					"name":"103246346 BLCAP; bladder cancer associated protein\tK29062 BLCAP; apoptosis inducing factor BLCAP"
				}
				]
			}
			]
		},
		{
			"name":"Other factors with a suspected DNA repair function",
			"children":[
			{
				"name":"DNA polymerases",
				"children":[
				{
					"name":"103228671 POLQ; DNA polymerase theta\tK02349 POLQ; DNA polymerase theta [EC:2.7.7.7]"
				},
				{
					"name":"103242185 MYBBP1A; MYB binding protein 1a\tK02331 POL5; DNA polymerase phi [EC:2.7.7.7]"
				},
				{
					"name":"103236615 PRIMPOL; primase and DNA directed polymerase\tK22761 PRIMPOL; DNA-directed primase\/polymerase protein [EC:2.7.7.102 2.7.7.7]"
				}
				]
			},
			{
				"name":"Nucleases",
				"children":[
				{
					"name":"103227588 TREX1; three prime repair exonuclease 1\tK10790 TREX1; three prime repair exonuclease 1 [EC:3.1.11.2]"
				},
				{
					"name":"103232785 TREX2; three prime repair exonuclease 2\tK10791 TREX2; three prime repair exonuclease 2 [EC:3.1.11.2]"
				},
				{
					"name":"103216540 DCLRE1A; DNA cross-link repair 1A\tK15340 DCLRE1A; DNA cross-link repair 1A protein"
				},
				{
					"name":"103224182 DCLRE1B; DNA cross-link repair 1B\tK15341 DCLRE1B; DNA cross-link repair 1B protein [EC:3.1.-.-]"
				},
				{
					"name":"103225026 EXO5; exonuclease 5\tK17815 EXO5; exonuclease V [EC:3.1.-.-]"
				},
				{
					"name":"103243694 ENDOV; endonuclease V\tK21813 ENDOV; endonuclease V [EC:3.1.26.-]"
				},
				{
					"name":"103216987 ZRANB3; zinc finger RANBP2-type containing 3\tK25861 ZRANB3; DNA annealing helicase and endonuclease ZRANB3 [EC:5.6.2.- 3.1.-.-]"
				},
				{
					"name":"103234129 ANKLE1; ankyrin repeat and LEM domain containing 1\tK21411 ANKLE1; ankyrin repeat and LEM domain-containing protein 1"
				}
				]
			},
			{
				"name":"Helicases",
				"children":[
				{
					"name":"103235905 HELQ; helicase, POLQ-like\tK19178 HELQ; POLQ-like helicase [EC:5.6.2.4]"
				},
				{
					"name":"103219822 DNA excision repair protein ERCC-6\tK20098 ERCC6L2; DNA excision repair protein ERCC-6-like 2 [EC:5.6.2.-]"
				}
				]
			},
			{
				"name":"PSO4 complex",
				"children":[
				{
					"name":"103234589 PRPF19; pre-mRNA processing factor 19\tK10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]"
				},
				{
					"name":"103221429 CDC5L; cell division cycle 5 like\tK12860 CDC5L; pre-mRNA-splicing factor CDC5\/CEF1"
				},
				{
					"name":"103224172 BCAS2; BCAS2, pre-mRNA processing factor\tK12861 BCAS2; pre-mRNA-splicing factor SPF27"
				},
				{
					"name":"103236418 PLRG1; pleiotropic regulator 1\tK12862 PLRG1; pleiotropic regulator 1"
				}
				]
			},
			{
				"name":"Modulation of nucleotide pools",
				"children":[
				{
					"name":"103214400 NUDT15; nudix hydrolase 15\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]"
				},
				{
					"name":"103246873 NUDT1; nudix hydrolase 1\tK17816 NUDT1; 8-oxo-dGTP diphosphatase \/ 2-hydroxy-dATP diphosphatase [EC:3.6.1.55 3.6.1.56]"
				},
				{
					"name":"103215715 NUDT18; nudix hydrolase 18\tK17817 NUDT18; 8-oxo-dGDP phosphatase [EC:3.6.1.58]"
				},
				{
					"name":"103245674 DUT; deoxyuridine triphosphatase\tK01520 dut; dUTP diphosphatase [EC:3.6.1.23]"
				},
				{
					"name":"103247970 RRM1; ribonucleotide reductase catalytic subunit M1\tK10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]"
				},
				{
					"name":"103220834 RRM2; ribonucleotide reductase regulatory subunit M2\tK10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]"
				},
				{
					"name":"103237238 RRM2B; ribonucleotide reductase regulatory TP53 inducible subunit M2B\tK10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic type",
		"children":[
		{
			"name":"SSBR (single strand breaks repair)",
			"children":[
			{
				"name":"Direct repair",
				"children":[
				{
					"name":"103216705 MGMT; O-6-methylguanine-DNA methyltransferase\tK00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]"
				}
				]
			},
			{
				"name":"BER (base exicision repair)",
				"children":[
				{
					"name":"DNA glycosylases",
					"children":[
					{
						"name":"103239082 UNG; uracil DNA glycosylase\tK03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]"
					},
					{
						"name":"103238429 SMUG1; single-strand-selective monofunctional uracil-DNA glycosylase 1\tK10800 SMUG1; single-strand selective monofunctional uracil DNA glycosylase [EC:3.2.2.-]"
					},
					{
						"name":"103225339 MPG; N-methylpurine DNA glycosylase\tK03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]"
					},
					{
						"name":"103224913 MUTYH; mutY DNA glycosylase\tK03575 mutY; A\/G-specific adenine glycosylase [EC:3.2.2.31]"
					},
					{
						"name":"103226630 NTHL1; nth like DNA glycosylase 1\tK10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]"
					}
					]
				},
				{
					"name":"AP endonucleases"
				},
				{
					"name":"RecJ"
				},
				{
					"name":"DNA ligase"
				},
				{
					"name":"DNA polymerase I"
				}
				]
			},
			{
				"name":"NER (nucleotide excision repair)",
				"children":[
				{
					"name":"GGR (global genome repair) factors"
				},
				{
					"name":"TCR (transcription coupled repair) factors",
					"children":[
					{
						"name":"DNA-directed RNA polymerase complex (RNAP)"
					},
					{
						"name":"TRCF (transcription-repair coupling factor)"
					}
					]
				}
				]
			},
			{
				"name":"MMR (mismatch excision repair)",
				"children":[
				{
					"name":"Mismatch and loop recognition factors"
				},
				{
					"name":"Molecular matchmaker"
				},
				{
					"name":"Strand discrimination factor"
				},
				{
					"name":"DNA exonucleases"
				},
				{
					"name":"DNA polymerase III holoenzyme"
				},
				{
					"name":"DNA ligase"
				},
				{
					"name":"Other MMR factors",
					"children":[
					{
						"name":"103227037 SSBP1; single stranded DNA binding protein 1\tK03111 ssb; single-strand DNA-binding protein"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"DSBR (double strand breaks repair)",
			"children":[
			{
				"name":"HR (homologous recombination)",
				"children":[
				{
					"name":"RecBC pathway proteins"
				},
				{
					"name":"RecFOR pathway proteins"
				},
				{
					"name":"AddAB pathway proteins"
				},
				{
					"name":"Other HR factor"
				},
				{
					"name":"Archaeal homologous recombinant proteins"
				}
				]
			},
			{
				"name":"NHEJ (non-homologous end-joining)",
				"children":[
				{
					"name":"Two-component NHEJ DNA repair complex"
				},
				{
					"name":"SHIIR (short-homology-independent illegitimate recombination)",
					"children":[
					{
						"name":"Facilitator"
					},
					{
						"name":"Supressor"
					}
					]
				},
				{
					"name":"SHDIR (short-homology-dependent illegitimate recombination)",
					"children":[
					{
						"name":"RecET pathway"
					},
					{
						"name":"Facilitator"
					},
					{
						"name":"Supressor"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"TLS (translesion DNA synthesis) factors",
			"children":[
			{
				"name":"Y-family DNA polymerases"
			},
			{
				"name":"Other SOS response factors",
				"children":[
				{
					"name":"103227037 SSBP1; single stranded DNA binding protein 1\tK03111 ssb; single-strand DNA-binding protein"
				}
				]
			}
			]
		},
		{
			"name":"Other factors with a suspected DNA repair function",
			"children":[
			{
				"name":"DNA polymerase"
			},
			{
				"name":"DNA helicases"
			},
			{
				"name":"Modulation of nucleotide pools",
				"children":[
				{
					"name":"103214400 NUDT15; nudix hydrolase 15\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]"
				},
				{
					"name":"103245674 DUT; deoxyuridine triphosphatase\tK01520 dut; dUTP diphosphatase [EC:3.6.1.23]"
				}
				]
			},
			{
				"name":"Others"
			}
			]
		}
		]
	}
	]
}