{
	"name":"cso03000",
	"children":[
	{
		"name":"Eukaryotic type",
		"children":[
		{
			"name":"Basic leucine zipper (bZIP)",
			"children":[
			{
				"name":"AP-1(-like) components, Jun"
			},
			{
				"name":"AP-1(-like) components, Fos"
			},
			{
				"name":"AP-1(-like) components, Maf"
			},
			{
				"name":"AP-1(-like) components, NF-E2"
			},
			{
				"name":"AP-1(-like) components, Fungal regulators"
			},
			{
				"name":"AP-1(-like) components, CRE-BP\/ATF"
			},
			{
				"name":"CREB"
			},
			{
				"name":"C\/EBP-like factors"
			},
			{
				"name":"bZIP\/PAR"
			},
			{
				"name":"Plant bZIP factors"
			},
			{
				"name":"ZIP only"
			}
			]
		},
		{
			"name":"Basic helix-loop-helix (bHLH)",
			"children":[
			{
				"name":"Ubiquitous (class A) factors"
			},
			{
				"name":"Myogenic transcription factors"
			},
			{
				"name":"Achaete-Scute"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, Lymphoid factors"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, Mesodermal Twist-like factors"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, HEN"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, Mesp"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, Atonal"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, Pancreatic factors"
			},
			{
				"name":"Hairy, Hairy\/E(SPL)"
			},
			{
				"name":"Hairy, Fungal regulators"
			},
			{
				"name":"Factors with PAS domain"
			},
			{
				"name":"Yabby"
			},
			{
				"name":"INO"
			},
			{
				"name":"HLH domain only"
			}
			]
		},
		{
			"name":"Basic helix-loop-helix\/leucine zipper (bHLH-ZIP)",
			"children":[
			{
				"name":"Ubiquitous bHLH-ZIP factors"
			},
			{
				"name":"Cell cycle controlling factors, Myc"
			},
			{
				"name":"Cell cycle controlling factors, Mad\/Max"
			},
			{
				"name":"Other bHLH-ZIP factors"
			}
			]
		},
		{
			"name":"Other basic domains",
			"children":[
			{
				"name":"NF-1"
			},
			{
				"name":"RF-X"
			},
			{
				"name":"AP-2 (bHSH)"
			}
			]
		},
		{
			"name":"Zinc finger",
			"children":[
			{
				"name":"Cys4 thyroid hormone receptor-like"
			},
			{
				"name":"Cys4 hepatocyte nuclear factor 4-like"
			},
			{
				"name":"Cys4 estrogen receptor-like"
			},
			{
				"name":"Cys4 nerve growth factor IB-like"
			},
			{
				"name":"Cys4 Fushi tarazu-F1-like"
			},
			{
				"name":"Cys4 germ cell nuclear factor"
			},
			{
				"name":"Cys4 Knirps\/DAX1-like"
			},
			{
				"name":"Cys4 GATA-factors"
			},
			{
				"name":"Cys2His2 SP\/KLF family and related proteins"
			},
			{
				"name":"Cys2His2 GLI-like"
			},
			{
				"name":"Cys2His2 Snail"
			},
			{
				"name":"Cys2His2 BTB-ZF factors"
			},
			{
				"name":"Cys2His2 BED"
			},
			{
				"name":"Cys2His2 PRDM"
			},
			{
				"name":"Cys2His2 metabolic regulators in fungi"
			},
			{
				"name":"Cys2His2 others"
			},
			{
				"name":"Cys2HisCys zinc factors"
			},
			{
				"name":"Cys3His zinc factors"
			},
			{
				"name":"Cys2CysHis zinc factors"
			},
			{
				"name":"CXXC CpG-binding proteins"
			},
			{
				"name":"Cys6 metabolic regulators in fungi"
			},
			{
				"name":"Other zinc fingers"
			}
			]
		},
		{
			"name":"Helix-turn-helix",
			"children":[
			{
				"name":"Homeo domain ANTP: HOXL"
			},
			{
				"name":"Homeo domain ANTP: NKL"
			},
			{
				"name":"Homeo domain Paired-related"
			},
			{
				"name":"Homeo domain LIM"
			},
			{
				"name":"Homeo domain POU"
			},
			{
				"name":"Homeo domain SINE"
			},
			{
				"name":"Homeo domain ZF"
			},
			{
				"name":"Homeo domain CUT"
			},
			{
				"name":"Homeo domain PROS"
			},
			{
				"name":"Homeo domain TALE"
			},
			{
				"name":"Homeo domain other"
			},
			{
				"name":"Fork head\/winged helix developmental regulators"
			},
			{
				"name":"Fork head\/winged helix tissue-specific regulators"
			},
			{
				"name":"Fork head\/winged helix cell cycle-controlling factors, E2F"
			},
			{
				"name":"Fork head\/winged helix cell cycle-controlling factors, DP"
			},
			{
				"name":"Fork head\/winged helix other regulators"
			},
			{
				"name":"Stork head\/winged helix factors"
			},
			{
				"name":"Heat shock factors"
			},
			{
				"name":"Tryptophan clusters Myb, Myb-factors"
			},
			{
				"name":"Tryptophan clusters Myb, Myb-like factors"
			},
			{
				"name":"Tryptophan clusters Ets-type"
			},
			{
				"name":"Tryptophan clusters interferon-regulating factors"
			},
			{
				"name":"TEA domain"
			},
			{
				"name":"ARID"
			}
			]
		},
		{
			"name":"beta-Scaffold factors with minor groove contacts",
			"children":[
			{
				"name":"RHR (Rel homology region) Rel\/Ankyrin"
			},
			{
				"name":"RHR (Rel homology region) Ankyrin only"
			},
			{
				"name":"RHR (Rel homology region) NF-AT"
			},
			{
				"name":"STAT"
			},
			{
				"name":"p53"
			},
			{
				"name":"MADS-box regulators of differentiation, MEF-2"
			},
			{
				"name":"MADS-box regulators of differentiation, Homeotic genes"
			},
			{
				"name":"MADS-box regulators of differentiation, Yeast regulators"
			},
			{
				"name":"MADS-box responders to external signals"
			},
			{
				"name":"SAND domain-containing proteins"
			},
			{
				"name":"TATA-binding proteins"
			},
			{
				"name":"HMG SOX"
			},
			{
				"name":"HMG TCF-1"
			},
			{
				"name":"HMG TOX"
			},
			{
				"name":"HMG2-related"
			},
			{
				"name":"UBF"
			},
			{
				"name":"Other HMG box factors"
			},
			{
				"name":"Heteromeric CCAAT factors"
			},
			{
				"name":"Grainyhead"
			},
			{
				"name":"Cold-shock domain factors, DbpA-like"
			},
			{
				"name":"Cold-shock domain factors, YB-1\/DbpB-like"
			},
			{
				"name":"Cold-shock domain factors, FRG Y2-like"
			},
			{
				"name":"Runt"
			},
			{
				"name":"MYRF"
			}
			]
		},
		{
			"name":"Other transcription factors",
			"children":[
			{
				"name":"HMGI(Y)"
			},
			{
				"name":"NUPR"
			},
			{
				"name":"Pocket domain Rb"
			},
			{
				"name":"Pocket domain CBP"
			},
			{
				"name":"T-box"
			},
			{
				"name":"DMRT"
			},
			{
				"name":"LRRFIP"
			},
			{
				"name":"TCP"
			},
			{
				"name":"AP2\/ERF"
			},
			{
				"name":"WRKY"
			},
			{
				"name":"LOB"
			},
			{
				"name":"GRAS"
			},
			{
				"name":"NAC"
			},
			{
				"name":"Copper-fist proteins fungal regulators"
			},
			{
				"name":"Others"
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic type",
		"children":[
		{
			"name":"Helix-turn-helix",
			"children":[
			{
				"name":"AraC family"
			},
			{
				"name":"LysR family",
				"children":[
				{
					"name":"CLS_19580 transcriptional regulator, LysR family\tK11921 cynR; LysR family transcriptional regulator, cyn operon transcriptional activator"
				},
				{
					"name":"CLS_16390 Transcriptional regulator\tK21900 cysL; LysR family transcriptional regulator, transcriptional activator of the cysJI operon"
				}
				]
			},
			{
				"name":"DeoR family",
				"children":[
				{
					"name":"CLS_13530 sporulation transcriptional regulator SpoIIID\tK06283 spoIIID; putative DeoR family transcriptional regulator, stage III sporulation protein D"
				}
				]
			},
			{
				"name":"LacI family",
				"children":[
				{
					"name":"CLS_27430 Transcriptional regulators\tK02529 galR; LacI family transcriptional regulator, galactose operon repressor"
				}
				]
			},
			{
				"name":"GntR family",
				"children":[
				{
					"name":"CLS_00550 trehalose operon repressor, B. subtilis-type\tK03486 treR2; GntR family transcriptional regulator, trehalose operon transcriptional repressor"
				},
				{
					"name":"CLS_02980 transcriptional regulator, GntR family\tK03486 treR2; GntR family transcriptional regulator, trehalose operon transcriptional repressor"
				},
				{
					"name":"CLS_33590 transcriptional regulator, GntR family\tK03710 K03710; GntR family transcriptional regulator"
				},
				{
					"name":"CLS_17300 transcriptional regulator, GntR family\tK00375 K00375; GntR family transcriptional regulator \/ MocR family aminotransferase"
				}
				]
			},
			{
				"name":"TetR\/AcrR family",
				"children":[
				{
					"name":"CLS_24760 Transcriptional regulator\tK09017 rutR; TetR\/AcrR family transcriptional regulator"
				},
				{
					"name":"CLS_34380 Transcriptional regulator\tK09017 rutR; TetR\/AcrR family transcriptional regulator"
				}
				]
			},
			{
				"name":"Lrp\/AsnC family"
			},
			{
				"name":"LuxR family"
			},
			{
				"name":"MarR family"
			},
			{
				"name":"MerR family",
				"children":[
				{
					"name":"CLS_17770 Predicted transcriptional regulators\tK19591 cueR; MerR family transcriptional regulator, copper efflux regulator"
				},
				{
					"name":"CLS_11300 transcriptional regulator, MerR family\tK21745 adhR; MerR family transcriptional regulator, aldehyde-responsive regulator"
				},
				{
					"name":"CLS_10150 Predicted transcriptional regulators\tK22491 litR; MerR family transcriptional regulator, light-induced transcriptional regulator"
				}
				]
			},
			{
				"name":"Fur family",
				"children":[
				{
					"name":"CLS_18440 Fe2+\/Zn2+ uptake regulation proteins\tK03711 fur; Fur family transcriptional regulator, ferric uptake regulator"
				},
				{
					"name":"CLS_12900 Fe2+\/Zn2+ uptake regulation proteins\tK09825 perR; Fur family transcriptional regulator, peroxide stress response regulator"
				}
				]
			},
			{
				"name":"IclR family"
			},
			{
				"name":"CRP\/FNR family"
			},
			{
				"name":"Rrf2 family"
			},
			{
				"name":"ArsR family",
				"children":[
				{
					"name":"CLS_36710 transcriptional regulator, ArsR family\tK21903 cadC; ArsR family transcriptional regulator, lead\/cadmium\/zinc\/bismuth-responsive transcriptional repressor"
				}
				]
			},
			{
				"name":"XRE family"
			},
			{
				"name":"PadR family",
				"children":[
				{
					"name":"CLS_00380 transcriptional regulator, PadR family\tK10947 K10947; PadR family transcriptional regulator"
				},
				{
					"name":"CLS_23820 transcriptional regulator, PadR family\tK10947 K10947; PadR family transcriptional regulator"
				}
				]
			},
			{
				"name":"Other families",
				"children":[
				{
					"name":"CLS_04550 Mn-dependent transcriptional regulator\tK03709 troR; DtxR family transcriptional regulator, Mn-dependent transcriptional regulator"
				},
				{
					"name":"CLS_06400 Mn-dependent transcriptional regulator\tK03709 troR; DtxR family transcriptional regulator, Mn-dependent transcriptional regulator"
				},
				{
					"name":"CLS_18400 Mn-dependent transcriptional regulator\tK03709 troR; DtxR family transcriptional regulator, Mn-dependent transcriptional regulator"
				},
				{
					"name":"CLS_17420 birA, biotin-[acetyl-CoA-carboxylase] ligase region\tK03524 birA; BirA family transcriptional regulator, biotin operon repressor \/ biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]"
				},
				{
					"name":"CLS_15420 transcriptional regulator, CdaR family\tK02647 cdaR; carbohydrate diacid regulator"
				},
				{
					"name":"CLS_24200 GTP-sensing transcriptional pleiotropic repressor CodY\tK03706 codY; transcriptional pleiotropic repressor"
				},
				{
					"name":"CLS_07730 Predicted transcriptional regulators\tK07726 K07726; putative transcriptional regulator"
				},
				{
					"name":"CLS_17890 Predicted transcriptional regulator\tK07727 K07727; putative transcriptional regulator"
				},
				{
					"name":"CLS_22290 Predicted transcriptional regulator\tK07727 K07727; putative transcriptional regulator"
				},
				{
					"name":"CLS_24800 Predicted transcriptional regulator\tK07727 K07727; putative transcriptional regulator"
				},
				{
					"name":"CLS_30910 Predicted transcriptional regulator\tK07727 K07727; putative transcriptional regulator"
				}
				]
			}
			]
		},
		{
			"name":"Ribbon-helix-helix",
			"children":[
			{
				"name":"CopG family"
			},
			{
				"name":"Other families"
			}
			]
		},
		{
			"name":"Other transcription factors",
			"children":[
			{
				"name":"BglG family",
				"children":[
				{
					"name":"CLS_24480 transcriptional antiterminator, BglG family\tK03488 licT; beta-glucoside operon transcriptional antiterminator"
				},
				{
					"name":"CLS_32010 transcriptional antiterminator, BglG family\tK03480 glcT; transcriptional antiterminator"
				},
				{
					"name":"CLS_37090 Transcriptional antiterminator\tK03491 licR; probable licABCH operon transcriptional regulator"
				}
				]
			},
			{
				"name":"Others",
				"children":[
				{
					"name":"CLS_08800 Uncharacterized protein conserved in bacteria\tK21600 csoR; CsoR family transcriptional regulator, copper-sensing transcriptional repressor"
				},
				{
					"name":"CLS_28130 Uncharacterized protein conserved in bacteria\tK21600 csoR; CsoR family transcriptional regulator, copper-sensing transcriptional repressor"
				},
				{
					"name":"CLS_00870 transcriptional regulator, AbrB family\tK04769 spoVT; AbrB family transcriptional regulator, stage V sporulation protein T"
				},
				{
					"name":"CLS_05650 ParB-like partition proteins\tK03497 parB; ParB family transcriptional regulator, chromosome partitioning protein"
				},
				{
					"name":"CLS_05720 ParB-like partition proteins\tK03497 parB; ParB family transcriptional regulator, chromosome partitioning protein"
				},
				{
					"name":"CLS_37000 Glycerol-3-phosphate responsive antiterminator (mRNA-binding)\tK02443 glpP; glycerol uptake operon antiterminator"
				},
				{
					"name":"CLS_13390 transcriptional regulator, ArgR family\tK03402 argR; transcriptional regulator of arginine metabolism"
				},
				{
					"name":"CLS_37710 heat-inducible transcription repressor HrcA\tK03705 hrcA; heat-inducible transcriptional repressor"
				},
				{
					"name":"CLS_07220 Putative transcription activator\tK03707 tenA; thiaminase (transcriptional activator TenA) [EC:3.5.99.2]"
				},
				{
					"name":"CLS_38040 mraZ protein\tK03925 mraZ; transcriptional regulator MraZ"
				}
				]
			}
			]
		}
		]
	}
	]
}