{
	"name":"ctp04121",
	"children":[
	{
		"name":"Ubiquitins and ubiquitin-like proteins",
		"children":[
		{
			"name":"Ubiquitins",
			"children":[
			{
				"name":"CTRG_05622 ubiquitin\tK08770 UBB_C; ubiquitin B\/C"
			},
			{
				"name":"CTRG_00044 60S ribosomal protein L40\tK02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e"
			},
			{
				"name":"CTRG_03742 ubiquitin\tK02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae"
			}
			]
		},
		{
			"name":"Ubiquitin-like proteins (UBLs)",
			"children":[
			{
				"name":"CTRG_00453 conserved hypothetical protein\tK12158 NEDD8; ubiquitin-like protein Nedd8"
			},
			{
				"name":"CTRG_03667 hypothetical protein\tK08336 ATG12; ubiquitin-like protein ATG12"
			},
			{
				"name":"CTRG_04125 conserved hypothetical protein\tK12161 URM1; ubiquitin related modifier 1"
			}
			]
		}
		]
	},
	{
		"name":"Ubiquitin-activating enzymes (E1)",
		"children":[
		{
			"name":"Ubiquitin activating enzyme",
			"children":[
			{
				"name":"CTRG_05715 ubiquitin-activating enzyme E1 1\tK03178 UBE1; ubiquitin-activating enzyme E1 [EC:6.2.1.45]"
			}
			]
		},
		{
			"name":"UBL-activating enzymes",
			"children":[
			{
				"name":"CTRG_05902 hypothetical protein\tK10684 UBLE1A; ubiquitin-like 1-activating enzyme E1 A [EC:6.2.1.45]"
			},
			{
				"name":"CTRG_03998 conserved hypothetical protein\tK10685 UBLE1B; ubiquitin-like 1-activating enzyme E1 B [EC:6.2.1.45]"
			},
			{
				"name":"CTRG_02993 hypothetical protein\tK10686 UBA3; NEDD8-activating enzyme E1 [EC:6.2.1.64]"
			},
			{
				"name":"CTRG_02677 conserved hypothetical protein\tK04532 NAE1; NEDD8-activating enzyme E1 regulatory subunit"
			},
			{
				"name":"CTRG_04079 hypothetical protein\tK11996 MOCS3; adenylyltransferase and sulfurtransferase [EC:2.7.7.80 2.8.1.11]"
			},
			{
				"name":"CTRG_00668 conserved hypothetical protein\tK08337 ATG7; ubiquitin-like modifier-activating enzyme ATG7"
			}
			]
		}
		]
	},
	{
		"name":"Ubiquitin-conjugating enzymes (E2)",
		"children":[
		{
			"name":"Ubiquitin-conjugating enzymes",
			"children":[
			{
				"name":"CTRG_05196 ubiquitin-conjugating enzyme E2 2\tK10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]"
			},
			{
				"name":"CTRG_05864 ubiquitin-conjugating enzyme E2 4\tK06689 UBE2D; ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]"
			},
			{
				"name":"CTRG_05912 ubiquitin-conjugating enzyme E2-18 kDa\tK04555 UBE2G2; ubiquitin-conjugating enzyme E2 G2 [EC:2.3.2.23]"
			},
			{
				"name":"CTRG_04589 ubiquitin-conjugating enzyme E2-21 kDa 2\tK10576 UBE2H; ubiquitin-conjugating enzyme E2 H [EC:2.3.2.23]"
			},
			{
				"name":"CTRG_02458 ubiquitin-conjugating enzyme E2 6\tK04554 UBE2J2; ubiquitin-conjugating enzyme E2 J2 [EC:2.3.2.23]"
			},
			{
				"name":"CTRG_02759 ubiquitin-conjugating enzyme E2-24 kDa\tK04649 UBE2K; ubiquitin-conjugating enzyme (huntingtin interacting protein 2) [EC:2.3.2.23]"
			},
			{
				"name":"CTRG_05270 ubiquitin-conjugating enzyme E2 13\tK10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]"
			},
			{
				"name":"CTRG_05171 hypothetical protein\tK02207 UBE2R; ubiquitin-conjugating enzyme E2 R [EC:2.3.2.23]"
			},
			{
				"name":"CTRG_01929 hypothetical protein\tK10688 UBE2W; ubiquitin-conjugating enzyme E2 W [EC:2.3.2.23 2.3.2.25]"
			},
			{
				"name":"CTRG_06148 hypothetical protein\tK10689 PEX4; peroxin-4 [EC:2.3.2.23]"
			}
			]
		},
		{
			"name":"UBL-conjugating enzymes",
			"children":[
			{
				"name":"CTRG_03100 ubiquitin-conjugating enzyme E2-18 kDa\tK10577 UBE2I; ubiquitin-conjugating enzyme E2 I"
			},
			{
				"name":"CTRG_06192 NEDD8-conjugating enzyme Ubc12\tK10579 UBE2M; ubiquitin-conjugating enzyme E2 M [EC:2.3.2.34]"
			},
			{
				"name":"CTRG_04389 hypothetical protein\tK08343 ATG3; ubiquitin-like-conjugating enzyme ATG3"
			}
			]
		}
		]
	},
	{
		"name":"Ubiquitin ligases (E3)",
		"children":[
		{
			"name":"HECT type E3",
			"children":[
			{
				"name":"CTRG_00080 conserved hypothetical protein\tK10589 UBE3C; ubiquitin-protein ligase E3 C [EC:2.3.2.26]"
			},
			{
				"name":"CTRG_01498 predicted protein\tK20803 UBE3D; ubiquitin-protein ligase E3 D [EC:2.3.2.26]"
			},
			{
				"name":"CTRG_00964 hypothetical protein\tK10590 TRIP12; E3 ubiquitin-protein ligase TRIP12 [EC:2.3.2.26]"
			},
			{
				"name":"CTRG_01844 E3 ubiquitin--protein ligase RSP5\tK10591 NEDD4; E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26]"
			},
			{
				"name":"CTRG_01307 hypothetical protein\tK10592 HUWE1; E3 ubiquitin-protein ligase HUWE1 [EC:2.3.2.26]"
			},
			{
				"name":"CTRG_02307 hypothetical protein\tK12232 HECTD2; E3 ubiquitin-protein ligase HECTD2 [EC:2.3.2.26]"
			},
			{
				"name":"HECT type E3 associated proteins"
			}
			]
		},
		{
			"name":"U-box type E3",
			"children":[
			{
				"name":"CTRG_02341 hypothetical protein\tK10597 UBE4B; ubiquitin conjugation factor E4 B [EC:2.3.2.27]"
			},
			{
				"name":"CTRG_03893 predicted protein\tK09561 STUB1; STIP1 homology and U-box containing protein 1 [EC:2.3.2.27]"
			},
			{
				"name":"CTRG_05101 predicted protein\tK09561 STUB1; STIP1 homology and U-box containing protein 1 [EC:2.3.2.27]"
			},
			{
				"name":"CTRG_05612 conserved hypothetical protein\tK10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]"
			}
			]
		},
		{
			"name":"Single Ring-finger type E3",
			"children":[
			{
				"name":"BRE1 proteins",
				"children":[
				{
					"name":"CTRG_05243 conserved hypothetical protein\tK10696 BRE1; E3 ubiquitin-protein ligase BRE1 [EC:2.3.2.27]"
				}
				]
			},
			{
				"name":"CBL proteins"
			},
			{
				"name":"SINA (Seven in absentia) proteins"
			},
			{
				"name":"Ligand of Numb proteins"
			},
			{
				"name":"March proteins",
				"children":[
				{
					"name":"CTRG_04997 conserved hypothetical protein\tK10661 MARCH6; E3 ubiquitin-protein ligase MARCH6 [EC:2.3.2.27]"
				}
				]
			},
			{
				"name":"MDM2\/MDM4 proteins"
			},
			{
				"name":"NFX1 proteins",
				"children":[
				{
					"name":"CTRG_00904 conserved hypothetical protein\tK12236 NFX1; transcriptional repressor NF-X1"
				}
				]
			},
			{
				"name":"Pellino proteins"
			},
			{
				"name":"Peripheral membrane proteins",
				"children":[
				{
					"name":"CTRG_00008 hypothetical protein\tK13346 PEX10; peroxin-10 [EC:2.3.2.27]"
				},
				{
					"name":"CTRG_01296 hypothetical protein\tK13345 PEX12; peroxin-12"
				},
				{
					"name":"CTRG_01657 conserved hypothetical protein\tK06664 PEX2; peroxin-2 [EC:2.3.2.27 2.3.2.36]"
				}
				]
			},
			{
				"name":"RBR proteins",
				"children":[
				{
					"name":"CTRG_03693 hypothetical protein\tK11968 ARIH1; ariadne-1 [EC:2.3.2.31]"
				},
				{
					"name":"CTRG_02498 hypothetical protein\tK11971 RNF14; E3 ubiquitin-protein ligase RNF14 [EC:2.3.2.31]"
				}
				]
			},
			{
				"name":"TRAF proteins"
			},
			{
				"name":"TRIM\/RBCC proteins"
			},
			{
				"name":"UBR box proteins",
				"children":[
				{
					"name":"CTRG_00339 hypothetical protein\tK10625 UBR1; E3 ubiquitin-protein ligase UBR1 [EC:2.3.2.27]"
				},
				{
					"name":"CTRG_00340 hypothetical protein\tK10625 UBR1; E3 ubiquitin-protein ligase UBR1 [EC:2.3.2.27]"
				},
				{
					"name":"CTRG_00402 conserved hypothetical protein\tK11979 UBR7; E3 ubiquitin-protein ligase UBR7 [EC:2.3.2.27]"
				}
				]
			},
			{
				"name":"ATL proteins"
			},
			{
				"name":"Other single Ring-finger type E3",
				"children":[
				{
					"name":"CTRG_01400 conserved hypothetical protein\tK10632 BRAP; BRCA1-associated protein [EC:2.3.2.27]"
				},
				{
					"name":"CTRG_00758 hypothetical protein\tK10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]"
				},
				{
					"name":"CTRG_00005 conserved hypothetical protein\tK22377 LTN1; E3 ubiquitin-protein ligase listerin [EC:2.3.2.27]"
				},
				{
					"name":"CTRG_02864 predicted protein\tK10627 RAD18; E3 ubiquitin-protein ligase RAD18 [EC:2.3.2.27]"
				},
				{
					"name":"CTRG_00091 predicted protein\tK26979 RNF10; E3 ubiquitin-protein ligase RNF10 [EC:2.3.2.27]"
				},
				{
					"name":"CTRG_05433 predicted protein\tK11984 SART1; U4\/U6.U5 tri-snRNP-associated protein 1"
				},
				{
					"name":"CTRG_01745 predicted protein\tK15710 SHPRH; E3 ubiquitin-protein ligase SHPRH [EC:5.6.2.- 2.3.2.27]"
				},
				{
					"name":"CTRG_00611 conserved hypothetical protein\tK10601 SYVN1; E3 ubiquitin-protein ligase synoviolin [EC:2.3.2.27]"
				},
				{
					"name":"CTRG_02828 hypothetical protein\tK22381 ZNF598; E3 ubiquitin-protein ligase ZNF598 [EC:2.3.2.27]"
				},
				{
					"name":"CTRG_05337 hypothetical protein\tK16275 BAH; E3 ubiquitin-protein ligase BAH [EC:2.3.2.27]"
				},
				{
					"name":"CTRG_05776 predicted protein\tK23788 TUL1; transmembrane E3 ubiquitin-protein ligase [EC:2.3.2.27]"
				},
				{
					"name":"CTRG_03016 conserved hypothetical protein\tK23787 DMA1_2; E3 ubiquitin-protein ligase DMA1\/2 [EC:2.3.2.27]"
				}
				]
			}
			]
		},
		{
			"name":"Atypical E3"
		},
		{
			"name":"UBL E3 ligases",
			"children":[
			{
				"name":"CTRG_02424 RING-box protein 1A\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
			},
			{
				"name":"CTRG_04453 predicted protein\tK04706 PIAS1; E3 SUMO-protein ligase PIAS1 [EC:2.3.2.-]"
			},
			{
				"name":"CTRG_02242 predicted protein\tK22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]"
			},
			{
				"name":"CTRG_01520 predicted protein\tK25662 RNF212; E3 SUMO-protein ligase RNF212 [EC:2.3.2.-]"
			},
			{
				"name":"CTRG_05683 predicted protein\tK17822 DCUN1D1_2; DCN1-like protein 1\/2"
			},
			{
				"name":"CTRG_05684 predicted protein\tK17822 DCUN1D1_2; DCN1-like protein 1\/2"
			}
			]
		},
		{
			"name":"Multi subunit type E3",
			"children":[
			{
				"name":"SCF complex",
				"children":[
				{
					"name":"Ring finger protein",
					"children":[
					{
						"name":"CTRG_02424 RING-box protein 1A\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
					}
					]
				},
				{
					"name":"Cullin",
					"children":[
					{
						"name":"CTRG_02143 conserved hypothetical protein\tK03347 CUL1; cullin 1"
					}
					]
				},
				{
					"name":"Adaptor protein",
					"children":[
					{
						"name":"CTRG_04163 suppressor of kinetochore protein 1\tK03094 SKP1; S-phase kinase-associated protein 1"
					}
					]
				},
				{
					"name":"Target recognizing subunit (F-box)",
					"children":[
					{
						"name":"CTRG_04413 protein MET30\tK10259 MET30; F-box and WD-40 domain protein MET30"
					},
					{
						"name":"CTRG_00845 cell division control protein 4\tK03361 CDC4; F-box and WD-40 domain protein CDC4"
					},
					{
						"name":"CTRG_06157 predicted protein\tK10273 FBXL7; F-box and leucine-rich repeat protein 7"
					},
					{
						"name":"CTRG_01004 conserved hypothetical protein\tK10276 FBXL10_11; F-box and leucine-rich repeat protein 10\/11 [EC:1.14.11.27]"
					},
					{
						"name":"CTRG_06022 hypothetical protein\tK03360 GRR1; F-box and leucine-rich repeat protein GRR1"
					},
					{
						"name":"CTRG_06183 conserved hypothetical protein\tK15068 DIA2; protein DIA2"
					},
					{
						"name":"CTRG_00193 conserved hypothetical protein\tK10295 FBXO9; F-box protein 9"
					},
					{
						"name":"CTRG_05296 hypothetical protein\tK15071 RCY1; recyclin-1"
					},
					{
						"name":"CTRG_05417 conserved hypothetical protein\tK15072 SAF1; SCF-associated factor 1"
					},
					{
						"name":"CTRG_04497 hypothetical protein\tK15073 UFO1; ubiquitin ligase complex F-box protein UFO1"
					}
					]
				}
				]
			},
			{
				"name":"Cul2 complex",
				"children":[
				{
					"name":"Ring finger protein",
					"children":[
					{
						"name":"CTRG_02424 RING-box protein 1A\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
					}
					]
				},
				{
					"name":"Cullin"
				},
				{
					"name":"Adoptor protein",
					"children":[
					{
						"name":"CTRG_04707 hypothetical protein\tK03872 ELOC; elongin-C"
					}
					]
				},
				{
					"name":"Target recognizing subunit"
				}
				]
			},
			{
				"name":"Cul3 complex",
				"children":[
				{
					"name":"Ring finger protein",
					"children":[
					{
						"name":"CTRG_02424 RING-box protein 1A\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
					}
					]
				},
				{
					"name":"Cullin",
					"children":[
					{
						"name":"CTRG_01046 conserved hypothetical protein\tK03869 CUL3; cullin 3"
					}
					]
				},
				{
					"name":"Adoptor and target recognizing subunit (BTB)",
					"children":[
					{
						"name":"CTRG_04881 conserved hypothetical protein\tK10520 ABTB1; ankyrin repeat and BTB\/POZ domain-containing protein 1"
					}
					]
				}
				]
			},
			{
				"name":"Cul4 complex",
				"children":[
				{
					"name":"Ring finger protein",
					"children":[
					{
						"name":"CTRG_02424 RING-box protein 1A\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
					}
					]
				},
				{
					"name":"Cullin",
					"children":[
					{
						"name":"CTRG_04267 conserved hypothetical protein\tK10609 CUL4; cullin 4"
					}
					]
				},
				{
					"name":"Adoptor protein"
				},
				{
					"name":"Target recognizing subunit (DCAF)",
					"children":[
					{
						"name":"CTRG_02555 conserved hypothetical protein\tK10570 ERCC8; DNA excision repair protein ERCC-8"
					},
					{
						"name":"CTRG_03179 conserved hypothetical protein\tK11805 DCAF7; DDB1- and CUL4-associated factor 7"
					},
					{
						"name":"CTRG_02124 protein SOF1\tK11806 DCAF13; DDB1- and CUL4-associated factor 13"
					},
					{
						"name":"CTRG_06202 protein SOF1\tK11806 DCAF13; DDB1- and CUL4-associated factor 13"
					},
					{
						"name":"CTRG_06223 protein SOF1\tK11806 DCAF13; DDB1- and CUL4-associated factor 13"
					},
					{
						"name":"CTRG_05207 conserved hypothetical protein\tK22382 WDR26; WD repeat-containing protein 26"
					},
					{
						"name":"CTRG_04866 conserved hypothetical protein\tK24755 WDR76; WD repeat-containing protein 76"
					}
					]
				}
				]
			},
			{
				"name":"Cul5 complex",
				"children":[
				{
					"name":"Ring finger protein"
				},
				{
					"name":"Cullin"
				},
				{
					"name":"Adoptor protein",
					"children":[
					{
						"name":"CTRG_04707 hypothetical protein\tK03872 ELOC; elongin-C"
					}
					]
				},
				{
					"name":"Target recognizing subunit"
				}
				]
			},
			{
				"name":"Cul7 complex",
				"children":[
				{
					"name":"Ring finger protein",
					"children":[
					{
						"name":"CTRG_02424 RING-box protein 1A\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
					}
					]
				},
				{
					"name":"Cullin"
				},
				{
					"name":"Adaptor protein",
					"children":[
					{
						"name":"CTRG_04163 suppressor of kinetochore protein 1\tK03094 SKP1; S-phase kinase-associated protein 1"
					}
					]
				},
				{
					"name":"Target recognizing subunit"
				}
				]
			},
			{
				"name":"Cul8 complex",
				"children":[
				{
					"name":"Ring finger protein",
					"children":[
					{
						"name":"CTRG_02424 RING-box protein 1A\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
					}
					]
				},
				{
					"name":"Cullin"
				},
				{
					"name":"Adaptor protein"
				},
				{
					"name":"Target recognizing subunit",
					"children":[
					{
						"name":"CTRG_01035 predicted protein\tK26122 MMS22; E3 ubiquitin-protein ligase substrate receptor MMS22"
					}
					]
				}
				]
			},
			{
				"name":"Cul9 complex",
				"children":[
				{
					"name":"Ring finger protein",
					"children":[
					{
						"name":"CTRG_02424 RING-box protein 1A\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
					}
					]
				},
				{
					"name":"Cullin"
				}
				]
			},
			{
				"name":"APC\/C",
				"children":[
				{
					"name":"Ring finger protein",
					"children":[
					{
						"name":"CTRG_05784 anaphase promoting complex subunit 11\tK03358 APC11; anaphase-promoting complex subunit 11"
					}
					]
				},
				{
					"name":"Cullin",
					"children":[
					{
						"name":"CTRG_05682 hypothetical protein\tK03349 APC2; anaphase-promoting complex subunit 2"
					}
					]
				},
				{
					"name":"Target recognizing subunit",
					"children":[
					{
						"name":"CTRG_02979 hypothetical protein\tK03363 CDC20; cell division cycle 20, cofactor of APC complex"
					},
					{
						"name":"CTRG_01113 hypothetical protein\tK03364 CDH1; cell division cycle 20-like protein 1, cofactor of APC complex"
					},
					{
						"name":"CTRG_02348 hypothetical protein\tK12782 AMA1; meiosis-specific APC\/C activator protein AMA1"
					}
					]
				},
				{
					"name":"Other subunits",
					"children":[
					{
						"name":"CTRG_04367 hypothetical protein\tK03348 APC1; anaphase-promoting complex subunit 1"
					},
					{
						"name":"CTRG_00962 hypothetical protein\tK03350 APC3; anaphase-promoting complex subunit 3"
					},
					{
						"name":"CTRG_05228 conserved hypothetical protein\tK03351 APC4; anaphase-promoting complex subunit 4"
					},
					{
						"name":"CTRG_04056 hypothetical protein\tK03352 APC5; anaphase-promoting complex subunit 5"
					},
					{
						"name":"CTRG_03877 conserved hypothetical protein\tK03353 APC6; anaphase-promoting complex subunit 6"
					},
					{
						"name":"CTRG_03039 conserved hypothetical protein\tK03355 APC8; anaphase-promoting complex subunit 8"
					},
					{
						"name":"CTRG_03984 hypothetical protein\tK03357 APC10; anaphase-promoting complex subunit 10"
					}
					]
				}
				]
			},
			{
				"name":"BRCC complex",
				"children":[
				{
					"name":"CTRG_00891 DNA repair protein RAD51\tK04482 RAD51; DNA repair protein RAD51"
				}
				]
			},
			{
				"name":"KPC complex"
			},
			{
				"name":"LUBAC complex"
			},
			{
				"name":"CTLH complex",
				"children":[
				{
					"name":"CTRG_04706 conserved hypothetical protein\tK23333 RMND5; E3 ubiquitin-protein transferase RMND5 [EC:2.3.2.27]"
				},
				{
					"name":"CTRG_02276 conserved hypothetical protein\tK18624 MAEA; macrophage erythroblast attacher"
				},
				{
					"name":"CTRG_05707 conserved hypothetical protein\tK23335 GID4; glucose-induced degradation protein 4"
				},
				{
					"name":"CTRG_00436 predicted protein\tK23338 GID8; glucose-induced degradation protein 8"
				},
				{
					"name":"CTRG_05207 conserved hypothetical protein\tK22382 WDR26; WD repeat-containing protein 26"
				}
				]
			},
			{
				"name":"ERAD complex"
			},
			{
				"name":"LMBR1L-GP78-UBAC2 complex"
			},
			{
				"name":"STUB1-CHIC2  complex",
				"children":[
				{
					"name":"CTRG_03893 predicted protein\tK09561 STUB1; STIP1 homology and U-box containing protein 1 [EC:2.3.2.27]"
				},
				{
					"name":"CTRG_05101 predicted protein\tK09561 STUB1; STIP1 homology and U-box containing protein 1 [EC:2.3.2.27]"
				}
				]
			},
			{
				"name":"SLX5-SLX8 complex",
				"children":[
				{
					"name":"CTRG_01404 predicted protein\tK22645 SLX5; E3 ubiquitin-protein ligase complex SLX5-SLX8 subunit SLX5 [EC:2.3.2.27]"
				},
				{
					"name":"CTRG_06176 hypothetical protein\tK22646 SLX8; E3 ubiquitin-protein ligase complex SLX5-SLX8 subunit SLX8 [EC:2.3.2.27]"
				}
				]
			},
			{
				"name":"Multi subunit type E3 associated proteins",
				"children":[
				{
					"name":"CTRG_05593 conserved hypothetical protein\tK17263 CAND1; cullin-associated NEDD8-dissociated protein 1"
				},
				{
					"name":"CTRG_04161 conserved hypothetical protein\tK24350 UBXN7; UBX domain-containing protein 7"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Deubiquitinating enzyme (DUB)",
		"children":[
		{
			"name":"Ubiquitin-specific proteases (UBPs)",
			"children":[
			{
				"name":"UCH",
				"children":[
				{
					"name":"CTRG_04248 hypothetical protein\tK05609 UCHL3; ubiquitin carboxyl-terminal hydrolase L3 [EC:3.4.19.12]"
				},
				{
					"name":"CTRG_06033 conserved hypothetical protein\tK05610 UCHL5; ubiquitin carboxyl-terminal hydrolase L5 [EC:3.4.19.12]"
				}
				]
			},
			{
				"name":"UBP\/USP",
				"children":[
				{
					"name":"CTRG_04237 hypothetical protein\tK11835 USP4_11; ubiquitin carboxyl-terminal hydrolase 4\/11 [EC:3.4.19.12]"
				},
				{
					"name":"CTRG_01426 hypothetical protein\tK11836 USP5_13; ubiquitin carboxyl-terminal hydrolase 5\/13 [EC:3.4.19.12]"
				},
				{
					"name":"CTRG_02092 conserved hypothetical protein\tK11838 USP7; ubiquitin carboxyl-terminal hydrolase 7 [EC:3.4.19.12]"
				},
				{
					"name":"CTRG_03675 hypothetical protein\tK11839 USP8; ubiquitin carboxyl-terminal hydrolase 8 [EC:3.4.19.12]"
				},
				{
					"name":"CTRG_03025 hypothetical protein\tK11841 USP10; ubiquitin carboxyl-terminal hydrolase 10 [EC:3.4.19.12]"
				},
				{
					"name":"CTRG_04315 hypothetical protein\tK11843 USP14; ubiquitin carboxyl-terminal hydrolase 14 [EC:3.4.19.12]"
				},
				{
					"name":"CTRG_02089 conserved hypothetical protein\tK11366 USP22_27_51; ubiquitin carboxyl-terminal hydrolase 22\/27\/51 [EC:3.4.19.12]"
				},
				{
					"name":"CTRG_00656 hypothetical protein\tK11849 USP25; ubiquitin carboxyl-terminal hydrolase 25 [EC:3.4.19.12]"
				},
				{
					"name":"CTRG_02447 predicted protein\tK11870 UBP1; ubiquitin carboxyl-terminal hydrolase 1 [EC:3.4.19.12]"
				},
				{
					"name":"CTRG_03923 hypothetical protein\tK11871 UBP7_11; ubiquitin carboxyl-terminal hydrolase 7\/11 [EC:3.4.19.12]"
				},
				{
					"name":"CTRG_01163 hypothetical protein\tK11872 UBP9_13; ubiquitin carboxyl-terminal hydrolase 9\/13 [EC:3.4.19.12]"
				},
				{
					"name":"CTRG_00472 hypothetical protein\tK11873 UBP10; ubiquitin carboxyl-terminal hydrolase 10 [EC:3.4.19.12]"
				},
				{
					"name":"CTRG_04611 conserved hypothetical protein\tK11874 UBP16; ubiquitin carboxyl-terminal hydrolase 16 [EC:3.4.19.12]"
				}
				]
			},
			{
				"name":"OTU",
				"children":[
				{
					"name":"CTRG_05364 conserved hypothetical protein\tK18342 OTUD6; OTU domain-containing protein 6 [EC:3.4.19.12]"
				}
				]
			},
			{
				"name":"MJD"
			},
			{
				"name":"MINDY",
				"children":[
				{
					"name":"CTRG_01859 conserved hypothetical protein\tK01309 MINDY1_2; ubiquitin carboxyl-terminal hydrolase MINDY-1\/2 [EC:3.4.19.12]"
				}
				]
			},
			{
				"name":"JAMM",
				"children":[
				{
					"name":"CTRG_03719 26S proteasome regulatory subunit RPN11\tK03030 PSMD14; 26S proteasome regulatory subunit N11"
				}
				]
			},
			{
				"name":"PPPDE"
			},
			{
				"name":"ZUFSP"
			},
			{
				"name":"BRISC complex"
			}
			]
		},
		{
			"name":"UBL-specific proteases (ULPs)",
			"children":[
			{
				"name":"CTRG_00737 conserved hypothetical protein\tK08592 SENP1; sentrin-specific protease 1 [EC:3.4.22.68]"
			},
			{
				"name":"CTRG_00755 conserved hypothetical protein\tK08592 SENP1; sentrin-specific protease 1 [EC:3.4.22.68]"
			},
			{
				"name":"CTRG_06173 predicted protein\tK08596 SENP7; sentrin-specific protease 7 [EC:3.4.22.68]"
			},
			{
				"name":"CTRG_02468 conserved hypothetical protein\tK08597 SENP8; sentrin-specific protease 8 [EC:3.4.22.68]"
			},
			{
				"name":"CTRG_04248 hypothetical protein\tK05609 UCHL3; ubiquitin carboxyl-terminal hydrolase L3 [EC:3.4.19.12]"
			},
			{
				"name":"CTRG_06151 conserved hypothetical protein\tK22762 DESI1; desumoylating isopeptidase 1 [EC:3.4.-.-]"
			},
			{
				"name":"COP9 signalosome (CSN) complex",
				"children":[
				{
					"name":"CTRG_02073 predicted protein\tK12176 COPS2; COP9 signalosome complex subunit 2"
				},
				{
					"name":"CTRG_00474 COP9 signalosome complex subunit 5\tK09613 COPS5; COP9 signalosome complex subunit 5 [EC:3.4.-.-]"
				},
				{
					"name":"CTRG_06021 conserved hypothetical protein\tK24364 CSN12; COP9 signalosome complex subunit 12"
				}
				]
			}
			]
		}
		]
	}
	]
}
