{ "name":"cvb00001", "children":[ { "name":"09100 Metabolism", "children":[ { "name":"09101 Carbohydrate metabolism", "children":[ { "name":"00010 Glycolysis \/ Gluconeogenesis [PATH:cvb00010]", "children":[ { "name":"R0135_05150 glk; (GenBank) glucokinase\tK00845 glk; glucokinase [EC:2.7.1.2]" }, { "name":"R0135_04165 pgi; (GenBank) glucose-6-phosphate isomerase\tK01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]" }, { "name":"R0135_08590 6-phosphofructokinase\tK21071 pfk; ATP-dependent phosphofructokinase \/ diphosphate-dependent phosphofructokinase [EC:2.7.1.11 2.7.1.90]" }, { "name":"R0135_00840 class I fructose-bisphosphate aldolase\tK01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]" }, { "name":"R0135_11290 fba; (GenBank) class II fructose-bisphosphate aldolase\tK01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]" }, { "name":"R0135_08715 tpiA; (GenBank) triose-phosphate isomerase\tK01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]" }, { "name":"R0135_03490 glyceraldehyde-3-phosphate dehydrogenase\tK00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]" }, { "name":"R0135_05170 gap; (GenBank) type I glyceraldehyde-3-phosphate dehydrogenase\tK00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]" }, { "name":"R0135_05470 gap; (GenBank) type I glyceraldehyde-3-phosphate dehydrogenase\tK00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]" }, { "name":"R0135_05475 glyceraldehyde 3-phosphate dehydrogenase NAD-binding domain-containing protein\tK00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]" }, { "name":"R0135_11295 phosphoglycerate kinase\tK00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]" }, { "name":"R0135_12395 gpmI; (GenBank) 2,3-bisphosphoglycerate-independent phosphoglycerate mutase\tK15633 gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12]" }, { "name":"R0135_05390 eno; (GenBank) phosphopyruvate hydratase\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]" }, { "name":"R0135_11045 pyk; (GenBank) pyruvate kinase\tK00873 PK; pyruvate kinase [EC:2.7.1.40]" }, { "name":"R0135_05285 ppdK; (GenBank) pyruvate, phosphate dikinase\tK01006 ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1]" }, { "name":"R0135_15350 ppsA; (GenBank) phosphoenolpyruvate synthase\tK01007 pps; pyruvate, water dikinase [EC:2.7.9.2]" }, { "name":"R0135_16750 aceE; (GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type\tK00163 aceE; pyruvate dehydrogenase E1 component [EC:1.2.4.1]" }, { "name":"R0135_16755 aceF; (GenBank) dihydrolipoyllysine-residue acetyltransferase\tK00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]" }, { "name":"R0135_02270 lpdA; (GenBank) dihydrolipoyl dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]" }, { "name":"R0135_06250 nifJ; (GenBank) pyruvate:ferredoxin (flavodoxin) oxidoreductase\tK03737 por; pyruvate-ferredoxin\/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.8.1]" }, { "name":"R0135_08105 2-oxoacid:acceptor oxidoreductase subunit alpha\tK00174 korA; 2-oxoglutarate\/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]" }, { "name":"R0135_10165 2-oxoacid:acceptor oxidoreductase subunit alpha\tK00174 korA; 2-oxoglutarate\/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]" }, { "name":"R0135_08100 2-oxoacid:ferredoxin oxidoreductase subunit beta\tK00175 korB; 2-oxoglutarate\/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]" }, { "name":"R0135_10160 2-oxoacid:ferredoxin oxidoreductase subunit beta\tK00175 korB; 2-oxoglutarate\/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]" }, { "name":"R0135_00320 S-(hydroxymethyl)glutathione dehydrogenase\/class III alcohol dehydrogenase\tK00121 frmA; S-(hydroxymethyl)glutathione dehydrogenase \/ alcohol dehydrogenase [EC:1.1.1.284 1.1.1.1]" }, { "name":"R0135_01945 aldehyde dehydrogenase family protein\tK00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]" }, { "name":"R0135_08655 acs; (GenBank) acetate--CoA ligase\tK01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]" }, { "name":"R0135_12110 aldose 1-epimerase\tK01785 galM; aldose 1-epimerase [EC:5.1.3.3]" }, { "name":"R0135_11475 phosphomannomutase\/phosphoglucomutase\tK15778 pmm-pgm; phosphomannomutase \/ phosphoglucomutase [EC:5.4.2.8 5.4.2.2]" }, { "name":"R0135_06615 D-hexose-6-phosphate mutarotase\tK01792 E5.1.3.15; glucose-6-phosphate 1-epimerase [EC:5.1.3.15]" }, { "name":"R0135_09500 phosphoenolpyruvate carboxykinase\tK01610 pckA; phosphoenolpyruvate carboxykinase (ATP) [EC:4.1.1.49]" } ] }, { "name":"00020 Citrate cycle (TCA cycle) [PATH:cvb00020]", "children":[ { "name":"R0135_02235 gltA; (GenBank) citrate synthase\tK01647 CS; citrate synthase [EC:2.3.3.1]" }, { "name":"R0135_03670 acnB; (GenBank) bifunctional aconitate hydratase 2\/2-methylisocitrate dehydratase\tK01682 acnB; aconitate hydratase 2 \/ 2-methylisocitrate dehydratase [EC:4.2.1.3 4.2.1.99]" }, { "name":"R0135_02625 icd; (GenBank) NADP-dependent isocitrate dehydrogenase\tK00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]" }, { "name":"R0135_04930 isocitrate\/isopropylmalate family dehydrogenase\tK00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]" }, { "name":"R0135_02260 2-oxoglutarate dehydrogenase E1 component\tK00164 OGDH; 2-oxoglutarate dehydrogenase E1 component [EC:1.2.4.2]" }, { "name":"R0135_02265 odhB; (GenBank) 2-oxoglutarate dehydrogenase complex dihydrolipoyllysine-residue succinyltransferase\tK00658 DLST; 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61]" }, { "name":"R0135_02270 lpdA; (GenBank) dihydrolipoyl dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]" }, { "name":"R0135_08105 2-oxoacid:acceptor oxidoreductase subunit alpha\tK00174 korA; 2-oxoglutarate\/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]" }, { "name":"R0135_10165 2-oxoacid:acceptor oxidoreductase subunit alpha\tK00174 korA; 2-oxoglutarate\/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]" }, { "name":"R0135_08100 2-oxoacid:ferredoxin oxidoreductase subunit beta\tK00175 korB; 2-oxoglutarate\/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]" }, { "name":"R0135_10160 2-oxoacid:ferredoxin oxidoreductase subunit beta\tK00175 korB; 2-oxoglutarate\/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]" }, { "name":"R0135_02280 sucD; (GenBank) succinate--CoA ligase subunit alpha\tK01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]" }, { "name":"R0135_02275 sucC; (GenBank) ADP-forming succinate--CoA ligase subunit beta\tK01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]" }, { "name":"R0135_02250 sdhA; (GenBank) succinate dehydrogenase flavoprotein subunit\tK00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]" }, { "name":"R0135_02255 succinate dehydrogenase iron-sulfur subunit\tK00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]" }, { "name":"R0135_02240 sdhC; (GenBank) succinate dehydrogenase, cytochrome b556 subunit\tK00241 sdhC; succinate dehydrogenase cytochrome b subunit" }, { "name":"R0135_02245 sdhD; (GenBank) succinate dehydrogenase, hydrophobic membrane anchor protein\tK00242 sdhD; succinate dehydrogenase membrane anchor subunit" }, { "name":"R0135_08265 fumarate reductase flavoprotein subunit\tK00233 frdA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1 7.1.1.12]" }, { "name":"R0135_08260 fumarate reductase iron-sulfur subunit\tK25995 frdB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1 7.1.1.12]" }, { "name":"R0135_08270 fumarate reductase cytochrome b subunit\tK25996 frdC; succinate dehydrogenase subunit C" }, { "name":"R0135_16950 fumarate hydratase\tK01676 E4.2.1.2A; fumarate hydratase, class I [EC:4.2.1.2]" }, { "name":"R0135_02115 malate dehydrogenase\tK00024 mdh; malate dehydrogenase [EC:1.1.1.37]" }, { "name":"R0135_09500 phosphoenolpyruvate carboxykinase\tK01610 pckA; phosphoenolpyruvate carboxykinase (ATP) [EC:4.1.1.49]" }, { "name":"R0135_16750 aceE; (GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type\tK00163 aceE; pyruvate dehydrogenase E1 component [EC:1.2.4.1]" }, { "name":"R0135_16755 aceF; (GenBank) dihydrolipoyllysine-residue acetyltransferase\tK00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]" }, { "name":"R0135_06250 nifJ; (GenBank) pyruvate:ferredoxin (flavodoxin) oxidoreductase\tK03737 por; pyruvate-ferredoxin\/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.8.1]" } ] }, { "name":"00030 Pentose phosphate pathway [PATH:cvb00030]", "children":[ { "name":"R0135_04165 pgi; (GenBank) glucose-6-phosphate isomerase\tK01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]" }, { "name":"R0135_05140 zwf; (GenBank) glucose-6-phosphate dehydrogenase\tK00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363]" }, { "name":"R0135_05135 pgl; (GenBank) 6-phosphogluconolactonase\tK01057 PGLS; 6-phosphogluconolactonase [EC:3.1.1.31]" }, { "name":"R0135_14515 rpe; (GenBank) ribulose-phosphate 3-epimerase\tK01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1]" }, { "name":"R0135_11305 tkt; (GenBank) transketolase\tK00615 E2.2.1.1; transketolase [EC:2.2.1.1]" }, { "name":"R0135_04630 tal; (GenBank) transaldolase\tK00616 TALDO1; transaldolase [EC:2.2.1.2]" }, { "name":"R0135_11235 rpiA; (GenBank) ribose-5-phosphate isomerase RpiA\tK01807 rpiA; ribose 5-phosphate isomerase A [EC:5.3.1.6]" }, { "name":"R0135_12205 deoC; (GenBank) deoxyribose-phosphate aldolase\tK01619 deoC; deoxyribose-phosphate aldolase [EC:4.1.2.4]" }, { "name":"R0135_12210 rbsK; (GenBank) ribokinase\tK28747 deoK; deoxyribokinase [EC:2.7.1.229]" }, { "name":"R0135_11475 phosphomannomutase\/phosphoglucomutase\tK15778 pmm-pgm; phosphomannomutase \/ phosphoglucomutase [EC:5.4.2.8 5.4.2.2]" }, { "name":"R0135_00910 ribose-phosphate diphosphokinase\tK00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]" }, { "name":"R0135_07555 ribose-phosphate pyrophosphokinase\tK00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]" }, { "name":"R0135_05155 edd; (GenBank) phosphogluconate dehydratase\tK01690 edd; phosphogluconate dehydratase [EC:4.2.1.12]" }, { "name":"R0135_05145 bifunctional 4-hydroxy-2-oxoglutarate aldolase\/2-dehydro-3-deoxy-phosphogluconate aldolase\tK01625 eda; 2-dehydro-3-deoxyphosphogluconate aldolase \/ (4S)-4-hydroxy-2-oxoglutarate aldolase [EC:4.1.2.14 4.1.3.42]" }, { "name":"R0135_00225 SMP-30\/gluconolactonase\/LRE family protein\tK01053 gnl; gluconolactonase [EC:3.1.1.17]" }, { "name":"R0135_14320 gluconate 2-dehydrogenase subunit 3 family protein\tK06152 E1.1.99.3G; gluconate 2-dehydrogenase gamma chain [EC:1.1.99.3]" }, { "name":"R0135_10595 sugar kinase\tK00874 kdgK; 2-dehydro-3-deoxygluconokinase [EC:2.7.1.45]" }, { "name":"R0135_00840 class I fructose-bisphosphate aldolase\tK01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]" }, { "name":"R0135_11290 fba; (GenBank) class II fructose-bisphosphate aldolase\tK01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]" }, { "name":"R0135_08590 6-phosphofructokinase\tK21071 pfk; ATP-dependent phosphofructokinase \/ diphosphate-dependent phosphofructokinase [EC:2.7.1.11 2.7.1.90]" } ] }, { "name":"00040 Pentose and glucuronate interconversions [PATH:cvb00040]", "children":[ { "name":"R0135_10615 kduD; (GenBank) 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase KduD\tK00065 kduD; 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase [EC:1.1.1.127]" }, { "name":"R0135_00500 UDP-glucose\/GDP-mannose dehydrogenase family protein\tK00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]" }, { "name":"R0135_15915 galU; (GenBank) UTP--glucose-1-phosphate uridylyltransferase GalU\tK00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]" }, { "name":"R0135_14515 rpe; (GenBank) ribulose-phosphate 3-epimerase\tK01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1]" } ] }, { "name":"00051 Fructose and mannose metabolism [PATH:cvb00051]", "children":[ { "name":"R0135_00520 ROK family protein\tK00847 E2.7.1.4; fructokinase [EC:2.7.1.4]" }, { "name":"R0135_11775 carbohydrate kinase\tK00847 E2.7.1.4; fructokinase [EC:2.7.1.4]" }, { "name":"R0135_15910 mannose-1-phosphate guanylyltransferase\/mannose-6-phosphate isomerase\tK16011 algA; mannose-1-phosphate guanylyltransferase \/ mannose-6-phosphate isomerase [EC:2.7.7.13 5.3.1.8]" }, { "name":"R0135_15920 phosphomannomutase\tK01840 manB; phosphomannomutase [EC:5.4.2.8]" }, { "name":"R0135_11475 phosphomannomutase\/phosphoglucomutase\tK15778 pmm-pgm; phosphomannomutase \/ phosphoglucomutase [EC:5.4.2.8 5.4.2.2]" }, { "name":"R0135_03805 gmd; (GenBank) GDP-mannose 4,6-dehydratase\tK01711 gmd; GDPmannose 4,6-dehydratase [EC:4.2.1.47]" }, { "name":"R0135_03800 GDP-L-fucose synthase\tK02377 TSTA3; GDP-L-fucose synthase [EC:1.1.1.271]" }, { "name":"R0135_16765 HAD-IIB family hydrolase\tK07026 E3.1.3.70; mannosyl-3-phosphoglycerate phosphatase [EC:3.1.3.70]" }, { "name":"R0135_08590 6-phosphofructokinase\tK21071 pfk; ATP-dependent phosphofructokinase \/ diphosphate-dependent phosphofructokinase [EC:2.7.1.11 2.7.1.90]" }, { "name":"R0135_00840 class I fructose-bisphosphate aldolase\tK01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]" }, { "name":"R0135_11290 fba; (GenBank) class II fructose-bisphosphate aldolase\tK01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]" }, { "name":"R0135_08715 tpiA; (GenBank) triose-phosphate isomerase\tK01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]" } ] }, { "name":"00052 Galactose metabolism [PATH:cvb00052]", "children":[ { "name":"R0135_12110 aldose 1-epimerase\tK01785 galM; aldose 1-epimerase [EC:5.1.3.3]" }, { "name":"R0135_05100 galK; (GenBank) galactokinase\tK00849 galK; galactokinase [EC:2.7.1.6]" }, { "name":"R0135_05105 UDP-glucose--hexose-1-phosphate uridylyltransferase\tK00965 galT; UDPglucose--hexose-1-phosphate uridylyltransferase [EC:2.7.7.12]" }, { "name":"R0135_00510 galE; (GenBank) UDP-glucose 4-epimerase GalE\tK01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2]" }, { "name":"R0135_15915 galU; (GenBank) UTP--glucose-1-phosphate uridylyltransferase GalU\tK00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]" }, { "name":"R0135_11475 phosphomannomutase\/phosphoglucomutase\tK15778 pmm-pgm; phosphomannomutase \/ phosphoglucomutase [EC:5.4.2.8 5.4.2.2]" }, { "name":"R0135_05150 glk; (GenBank) glucokinase\tK00845 glk; glucokinase [EC:2.7.1.2]" }, { "name":"R0135_05095 beta-galactosidase\tK12308 bgaB; beta-galactosidase [EC:3.2.1.23]" }, { "name":"R0135_05115 alpha-galactosidase\tK07407 E3.2.1.22B; alpha-galactosidase [EC:3.2.1.22]" }, { "name":"R0135_08590 6-phosphofructokinase\tK21071 pfk; ATP-dependent phosphofructokinase \/ diphosphate-dependent phosphofructokinase [EC:2.7.1.11 2.7.1.90]" } ] }, { "name":"00053 Ascorbate and aldarate metabolism [PATH:cvb00053]", "children":[ { "name":"R0135_00500 UDP-glucose\/GDP-mannose dehydrogenase family protein\tK00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]" }, { "name":"R0135_00225 SMP-30\/gluconolactonase\/LRE family protein\tK01053 gnl; gluconolactonase [EC:3.1.1.17]" }, { "name":"R0135_00505 NAD-dependent epimerase\tK08679 GAE; UDP-glucuronate 4-epimerase [EC:5.1.3.6]" }, { "name":"R0135_01945 aldehyde dehydrogenase family protein\tK00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]" } ] }, { "name":"00500 Starch and sucrose metabolism [PATH:cvb00500]", "children":[ { "name":"R0135_11795 glycoside hydrolase family 68 protein\tK00692 sacB; levansucrase [EC:2.4.1.10]" }, { "name":"R0135_15915 galU; (GenBank) UTP--glucose-1-phosphate uridylyltransferase GalU\tK00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]" }, { "name":"R0135_05190 bglX; (GenBank) beta-glucosidase BglX\tK05349 bglX; beta-glucosidase [EC:3.2.1.21]" }, { "name":"R0135_05195 glycoside hydrolase family 3 protein\tK05349 bglX; beta-glucosidase [EC:3.2.1.21]" }, { "name":"R0135_13810 glycoside hydrolase family 3 N-terminal domain-containing protein\tK05349 bglX; beta-glucosidase [EC:3.2.1.21]" }, { "name":"R0135_11475 phosphomannomutase\/phosphoglucomutase\tK15778 pmm-pgm; phosphomannomutase \/ phosphoglucomutase [EC:5.4.2.8 5.4.2.2]" }, { "name":"R0135_05150 glk; (GenBank) glucokinase\tK00845 glk; glucokinase [EC:2.7.1.2]" }, { "name":"R0135_04165 pgi; (GenBank) glucose-6-phosphate isomerase\tK01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]" }, { "name":"R0135_00520 ROK family protein\tK00847 E2.7.1.4; fructokinase [EC:2.7.1.4]" }, { "name":"R0135_11775 carbohydrate kinase\tK00847 E2.7.1.4; fructokinase [EC:2.7.1.4]" } ] }, { "name":"00620 Pyruvate metabolism [PATH:cvb00620]", "children":[ { "name":"R0135_08655 acs; (GenBank) acetate--CoA ligase\tK01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]" }, { "name":"R0135_06250 nifJ; (GenBank) pyruvate:ferredoxin (flavodoxin) oxidoreductase\tK03737 por; pyruvate-ferredoxin\/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.8.1]" }, { "name":"R0135_08105 2-oxoacid:acceptor oxidoreductase subunit alpha\tK00174 korA; 2-oxoglutarate\/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]" }, { "name":"R0135_10165 2-oxoacid:acceptor oxidoreductase subunit alpha\tK00174 korA; 2-oxoglutarate\/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]" }, { "name":"R0135_08100 2-oxoacid:ferredoxin oxidoreductase subunit beta\tK00175 korB; 2-oxoglutarate\/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]" }, { "name":"R0135_10160 2-oxoacid:ferredoxin oxidoreductase subunit beta\tK00175 korB; 2-oxoglutarate\/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]" }, { "name":"R0135_16750 aceE; (GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type\tK00163 aceE; pyruvate dehydrogenase E1 component [EC:1.2.4.1]" }, { "name":"R0135_16755 aceF; (GenBank) dihydrolipoyllysine-residue acetyltransferase\tK00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]" }, { "name":"R0135_02270 lpdA; (GenBank) dihydrolipoyl dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]" }, { "name":"R0135_00320 S-(hydroxymethyl)glutathione dehydrogenase\/class III alcohol dehydrogenase\tK00121 frmA; S-(hydroxymethyl)glutathione dehydrogenase \/ alcohol dehydrogenase [EC:1.1.1.284 1.1.1.1]" }, { "name":"R0135_11045 pyk; (GenBank) pyruvate kinase\tK00873 PK; pyruvate kinase [EC:2.7.1.40]" }, { "name":"R0135_05410 acetyl-CoA carboxylase carboxyltransferase subunit alpha\tK01962 accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15]" }, { "name":"R0135_14585 accB; (GenBank) acetyl-CoA carboxylase biotin carboxyl carrier protein\tK02160 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein" }, { "name":"R0135_14580 accC; (GenBank) acetyl-CoA carboxylase biotin carboxylase subunit\tK01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14]" }, { "name":"R0135_01945 aldehyde dehydrogenase family protein\tK00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]" }, { "name":"R0135_08195 L-lactate dehydrogenase\tK29125" }, { "name":"R0135_12240 VOC family protein\tK01759 GLO1; lactoylglutathione lyase [EC:4.4.1.5]" }, { "name":"R0135_02940 gloB; (GenBank) hydroxyacylglutathione hydrolase\tK01069 gloB; hydroxyacylglutathione hydrolase [EC:3.1.2.6]" }, { "name":"R0135_14795 MBL fold metallo-hydrolase\tK01069 gloB; hydroxyacylglutathione hydrolase [EC:3.1.2.6]" }, { "name":"R0135_05210 NADP-dependent malic enzyme\tK00029 maeB; malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+) [EC:1.1.1.40]" }, { "name":"R0135_05420 oadA; (GenBank) sodium-extruding oxaloacetate decarboxylase subunit alpha\tK01571 oadA; oxaloacetate decarboxylase (Na+ extruding) subunit alpha [EC:7.2.4.2]" }, { "name":"R0135_05415 sodium ion-translocating decarboxylase subunit beta\tK20509 madB; carboxybiotin decarboxylase [EC:7.2.4.1]" }, { "name":"R0135_05425 OadG family protein\tK01573 oadG; oxaloacetate decarboxylase (Na+ extruding) subunit gamma" }, { "name":"R0135_02115 malate dehydrogenase\tK00024 mdh; malate dehydrogenase [EC:1.1.1.37]" }, { "name":"R0135_16950 fumarate hydratase\tK01676 E4.2.1.2A; fumarate hydratase, class I [EC:4.2.1.2]" }, { "name":"R0135_08265 fumarate reductase flavoprotein subunit\tK00233 frdA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1 7.1.1.12]" }, { "name":"R0135_08260 fumarate reductase iron-sulfur subunit\tK25995 frdB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1 7.1.1.12]" }, { "name":"R0135_08270 fumarate reductase cytochrome b subunit\tK25996 frdC; succinate dehydrogenase subunit C" }, { "name":"R0135_05160 ppc; (GenBank) phosphoenolpyruvate carboxylase\tK01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31]" }, { "name":"R0135_09500 phosphoenolpyruvate carboxykinase\tK01610 pckA; phosphoenolpyruvate carboxykinase (ATP) [EC:4.1.1.49]" }, { "name":"R0135_05285 ppdK; (GenBank) pyruvate, phosphate dikinase\tK01006 ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1]" }, { "name":"R0135_15350 ppsA; (GenBank) phosphoenolpyruvate synthase\tK01007 pps; pyruvate, water dikinase [EC:2.7.9.2]" }, { "name":"R0135_07125 malate synthase G\tK01638 aceB; malate synthase [EC:2.3.3.9]" }, { "name":"R0135_00330 acetyl-CoA C-acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" }, { "name":"R0135_03970 acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" }, { "name":"R0135_04435 acetyl-CoA C-acyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" }, { "name":"R0135_05075 acetyl-CoA C-acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" }, { "name":"R0135_11080 acetyl-CoA C-acyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" }, { "name":"R0135_11085 acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" }, { "name":"R0135_12045 leuA; (GenBank) 2-isopropylmalate synthase\tK01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13]" } ] }, { "name":"00630 Glyoxylate and dicarboxylate metabolism [PATH:cvb00630]", "children":[ { "name":"R0135_01035 isocitrate lyase\tK01637 ICL; isocitrate\/methylisocitrate lyase [EC:4.1.3.1 4.1.3.30]" }, { "name":"R0135_07125 malate synthase G\tK01638 aceB; malate synthase [EC:2.3.3.9]" }, { "name":"R0135_02115 malate dehydrogenase\tK00024 mdh; malate dehydrogenase [EC:1.1.1.37]" }, { "name":"R0135_02235 gltA; (GenBank) citrate synthase\tK01647 CS; citrate synthase [EC:2.3.3.1]" }, { "name":"R0135_03670 acnB; (GenBank) bifunctional aconitate hydratase 2\/2-methylisocitrate dehydratase\tK01682 acnB; aconitate hydratase 2 \/ 2-methylisocitrate dehydratase [EC:4.2.1.3 4.2.1.99]" }, { "name":"R0135_08655 acs; (GenBank) acetate--CoA ligase\tK01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]" }, { "name":"R0135_00330 acetyl-CoA C-acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" }, { "name":"R0135_03970 acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" }, { "name":"R0135_04435 acetyl-CoA C-acyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" }, { "name":"R0135_05075 acetyl-CoA C-acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" }, { "name":"R0135_11080 acetyl-CoA C-acyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" }, { "name":"R0135_11085 acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" }, { "name":"R0135_02565 mce; (GenBank) methylmalonyl-CoA epimerase\tK05606 MCEE; methylmalonyl-CoA\/ethylmalonyl-CoA epimerase [EC:5.1.99.1]" }, { "name":"R0135_02570 scpA; (GenBank) methylmalonyl-CoA mutase\tK01847 MUT; methylmalonyl-CoA mutase [EC:5.4.99.2]" }, { "name":"R0135_16425 cobalamin-dependent protein\tK01849 E5.4.99.2B; methylmalonyl-CoA mutase, C-terminal domain [EC:5.4.99.2]" }, { "name":"R0135_16420 acyl-CoA mutase large subunit family protein\tK01848 E5.4.99.2A; methylmalonyl-CoA mutase, N-terminal domain [EC:5.4.99.2]" }, { "name":"R0135_08190 D-glycerate dehydrogenase\tK00015 gyaR; glyoxylate reductase [EC:1.1.1.26]" }, { "name":"R0135_10975 D-glycerate dehydrogenase\tK00015 gyaR; glyoxylate reductase [EC:1.1.1.26]" }, { "name":"R0135_03940 alanine--glyoxylate aminotransferase family protein\tK00830 AGXT; alanine-glyoxylate transaminase \/ serine-glyoxylate transaminase \/ serine-pyruvate transaminase [EC:2.6.1.44 2.6.1.45 2.6.1.51]" }, { "name":"R0135_08950 glutamine synthetase family protein\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]" }, { "name":"R0135_09260 glutamine synthetase family protein\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]" }, { "name":"R0135_10760 glutamine synthetase family protein\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]" }, { "name":"R0135_12435 glnA; (GenBank) glutamate--ammonia ligase\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]" }, { "name":"R0135_12885 glutamine synthetase family protein\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]" }, { "name":"R0135_15430 glyA; (GenBank) serine hydroxymethyltransferase\tK00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]" }, { "name":"R0135_00165 gcvP; (GenBank) aminomethyl-transferring glycine dehydrogenase\tK00281 GLDC; glycine cleavage system P protein (glycine dehydrogenase) [EC:1.4.4.2]" }, { "name":"R0135_12905 gcvT; (GenBank) glycine cleavage system aminomethyltransferase GcvT\tK00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]" }, { "name":"R0135_02270 lpdA; (GenBank) dihydrolipoyl dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]" }, { "name":"R0135_11180 gcvH; (GenBank) glycine cleavage system protein GcvH\tK02437 gcvH; glycine cleavage system H protein" }, { "name":"R0135_16760 hypothetical protein\tK15918 GLYK; D-glycerate 3-kinase [EC:2.7.1.31]" }, { "name":"R0135_05145 bifunctional 4-hydroxy-2-oxoglutarate aldolase\/2-dehydro-3-deoxy-phosphogluconate aldolase\tK01625 eda; 2-dehydro-3-deoxyphosphogluconate aldolase \/ (4S)-4-hydroxy-2-oxoglutarate aldolase [EC:4.1.2.14 4.1.3.42]" }, { "name":"R0135_04845 purU; (GenBank) formyltetrahydrofolate deformylase\tK01433 purU; formyltetrahydrofolate deformylase [EC:3.5.1.10]" }, { "name":"R0135_12330 acetamidase\/formamidase family protein\tK01455 fmdA; formamidase [EC:3.5.1.49]" } ] }, { "name":"00640 Propanoate metabolism [PATH:cvb00640]", "children":[ { "name":"R0135_08655 acs; (GenBank) acetate--CoA ligase\tK01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]" }, { "name":"R0135_04160 propionyl-CoA synthetase\tK01908 ACSS3; propionyl-CoA synthetase [EC:6.2.1.17]" }, { "name":"R0135_02270 lpdA; (GenBank) dihydrolipoyl dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]" }, { "name":"R0135_00290 MDR family oxidoreductase\tK19745 acuI; acrylyl-CoA reductase (NADPH) [EC:1.3.1.-]" }, { "name":"R0135_09395 fadB; (GenBank) fatty acid oxidation complex subunit alpha FadB\tK01825 fadB; 3-hydroxyacyl-CoA dehydrogenase \/ enoyl-CoA hydratase \/ 3-hydroxybutyryl-CoA epimerase \/ enoyl-CoA isomerase [EC:1.1.1.35 4.2.1.17 5.1.2.3 5.3.3.8]" }, { "name":"R0135_00335 3-hydroxyacyl-CoA dehydrogenase NAD-binding domain-containing protein\tK01782 fadJ; 3-hydroxyacyl-CoA dehydrogenase \/ enoyl-CoA hydratase \/ 3-hydroxybutyryl-CoA epimerase [EC:1.1.1.35 4.2.1.17 5.1.2.3]" }, { "name":"R0135_04935 iron-containing alcohol dehydrogenase\tK28061 dddB; 3-hydroxypropionate dehydrogenase" }, { "name":"R0135_05410 acetyl-CoA carboxylase carboxyltransferase subunit alpha\tK01962 accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15]" }, { "name":"R0135_14585 accB; (GenBank) acetyl-CoA carboxylase biotin carboxyl carrier protein\tK02160 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein" }, { "name":"R0135_14580 accC; (GenBank) acetyl-CoA carboxylase biotin carboxylase subunit\tK01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14]" }, { "name":"R0135_08990 aspartate aminotransferase family protein\tK00822 E2.6.1.18; beta-alanine--pyruvate transaminase [EC:2.6.1.18]" }, { "name":"R0135_02565 mce; (GenBank) methylmalonyl-CoA epimerase\tK05606 MCEE; methylmalonyl-CoA\/ethylmalonyl-CoA epimerase [EC:5.1.99.1]" }, { "name":"R0135_02570 scpA; (GenBank) methylmalonyl-CoA mutase\tK01847 MUT; methylmalonyl-CoA mutase [EC:5.4.99.2]" }, { "name":"R0135_16425 cobalamin-dependent protein\tK01849 E5.4.99.2B; methylmalonyl-CoA mutase, C-terminal domain [EC:5.4.99.2]" }, { "name":"R0135_16420 acyl-CoA mutase large subunit family protein\tK01848 E5.4.99.2A; methylmalonyl-CoA mutase, N-terminal domain [EC:5.4.99.2]" }, { "name":"R0135_02275 sucC; (GenBank) ADP-forming succinate--CoA ligase subunit beta\tK01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]" }, { "name":"R0135_02280 sucD; (GenBank) succinate--CoA ligase subunit alpha\tK01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]" }, { "name":"R0135_10955 CoA-acylating methylmalonate-semialdehyde dehydrogenase\tK00140 mmsA; malonate-semialdehyde dehydrogenase (acetylating) \/ methylmalonate-semialdehyde dehydrogenase [EC:1.2.1.18 1.2.1.27]" }, { "name":"R0135_03670 acnB; (GenBank) bifunctional aconitate hydratase 2\/2-methylisocitrate dehydratase\tK01682 acnB; aconitate hydratase 2 \/ 2-methylisocitrate dehydratase [EC:4.2.1.3 4.2.1.99]" }, { "name":"R0135_01035 isocitrate lyase\tK01637 ICL; isocitrate\/methylisocitrate lyase [EC:4.1.3.1 4.1.3.30]" }, { "name":"R0135_07990 glycerol dehydrogenase\tK00005 gldA; glycerol dehydrogenase [EC:1.1.1.6]" } ] }, { "name":"00650 Butanoate metabolism [PATH:cvb00650]", "children":[ { "name":"R0135_00330 acetyl-CoA C-acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" }, { "name":"R0135_03970 acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" }, { "name":"R0135_04435 acetyl-CoA C-acyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" }, { "name":"R0135_05075 acetyl-CoA C-acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" }, { "name":"R0135_11080 acetyl-CoA C-acyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" }, { "name":"R0135_11085 acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" }, { "name":"R0135_09105 3-hydroxyacyl-CoA dehydrogenase NAD-binding domain-containing protein\tK00074 paaH; 3-hydroxybutyryl-CoA dehydrogenase [EC:1.1.1.157]" }, { "name":"R0135_09395 fadB; (GenBank) fatty acid oxidation complex subunit alpha FadB\tK01825 fadB; 3-hydroxyacyl-CoA dehydrogenase \/ enoyl-CoA hydratase \/ 3-hydroxybutyryl-CoA epimerase \/ enoyl-CoA isomerase [EC:1.1.1.35 4.2.1.17 5.1.2.3 5.3.3.8]" }, { "name":"R0135_00335 3-hydroxyacyl-CoA dehydrogenase NAD-binding domain-containing protein\tK01782 fadJ; 3-hydroxyacyl-CoA dehydrogenase \/ enoyl-CoA hydratase \/ 3-hydroxybutyryl-CoA epimerase [EC:1.1.1.35 4.2.1.17 5.1.2.3]" }, { "name":"R0135_08825 enoyl-CoA hydratase\/isomerase family protein\tK01715 crt; short-chain-enoyl-CoA hydratase [EC:4.2.1.150]" }, { "name":"R0135_16780 trans-2-enoyl-CoA reductase family protein\tK00209 fabV; enoyl-[acyl-carrier protein] reductase \/ trans-2-enoyl-CoA reductase (NAD+) [EC:1.3.1.9 1.3.1.44]" }, { "name":"R0135_05415 sodium ion-translocating decarboxylase subunit beta\tK20509 madB; carboxybiotin decarboxylase [EC:7.2.4.1]" }, { "name":"R0135_02250 sdhA; (GenBank) succinate dehydrogenase flavoprotein subunit\tK00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]" }, { "name":"R0135_02255 succinate dehydrogenase iron-sulfur subunit\tK00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]" }, { "name":"R0135_02240 sdhC; (GenBank) succinate dehydrogenase, cytochrome b556 subunit\tK00241 sdhC; succinate dehydrogenase cytochrome b subunit" }, { "name":"R0135_02245 sdhD; (GenBank) succinate dehydrogenase, hydrophobic membrane anchor protein\tK00242 sdhD; succinate dehydrogenase membrane anchor subunit" }, { "name":"R0135_08265 fumarate reductase flavoprotein subunit\tK00233 frdA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1 7.1.1.12]" }, { "name":"R0135_08260 fumarate reductase iron-sulfur subunit\tK25995 frdB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1 7.1.1.12]" }, { "name":"R0135_08270 fumarate reductase cytochrome b subunit\tK25996 frdC; succinate dehydrogenase subunit C" }, { "name":"R0135_10365 aminotransferase\tK16871 POP2; 4-aminobutyrate---pyruvate transaminase [EC:2.6.1.96]" }, { "name":"R0135_01960 NAD-dependent succinate-semialdehyde dehydrogenase\tK00135 gabD; succinate-semialdehyde dehydrogenase \/ glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]" }, { "name":"R0135_06250 nifJ; (GenBank) pyruvate:ferredoxin (flavodoxin) oxidoreductase\tK03737 por; pyruvate-ferredoxin\/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.8.1]" }, { "name":"R0135_08105 2-oxoacid:acceptor oxidoreductase subunit alpha\tK00174 korA; 2-oxoglutarate\/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]" }, { "name":"R0135_10165 2-oxoacid:acceptor oxidoreductase subunit alpha\tK00174 korA; 2-oxoglutarate\/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]" }, { "name":"R0135_08100 2-oxoacid:ferredoxin oxidoreductase subunit beta\tK00175 korB; 2-oxoglutarate\/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]" }, { "name":"R0135_10160 2-oxoacid:ferredoxin oxidoreductase subunit beta\tK00175 korB; 2-oxoglutarate\/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]" }, { "name":"R0135_00130 hydroxymethylglutaryl-CoA lyase\tK01640 HMGCL; hydroxymethylglutaryl-CoA lyase [EC:4.1.3.4]" }, { "name":"R0135_15570 hydroxymethylglutaryl-CoA lyase\tK01640 HMGCL; hydroxymethylglutaryl-CoA lyase [EC:4.1.3.4]" }, { "name":"R0135_08320 CoA transferase subunit A\tK01028 scoA; 3-oxoacid CoA-transferase subunit A [EC:2.8.3.5]" }, { "name":"R0135_08315 3-oxoacid CoA-transferase subunit B\tK01029 scoB; 3-oxoacid CoA-transferase subunit B [EC:2.8.3.5]" }, { "name":"R0135_02995 serine hydrolase domain-containing protein\tK18372 acmB; methyl acetate hydrolase [EC:3.1.1.114]" }, { "name":"R0135_01660 5-guanidino-2-oxopentanoate decarboxylase\tK01652 E2.2.1.6L; acetolactate synthase I\/II\/III large subunit [EC:2.2.1.6]" }, { "name":"R0135_04490 acetolactate synthase large subunit\tK01652 E2.2.1.6L; acetolactate synthase I\/II\/III large subunit [EC:2.2.1.6]" }, { "name":"R0135_04820 ilvB; (GenBank) biosynthetic-type acetolactate synthase large subunit\tK01652 E2.2.1.6L; acetolactate synthase I\/II\/III large subunit [EC:2.2.1.6]" }, { "name":"R0135_05855 acetolactate synthase large subunit\tK01652 E2.2.1.6L; acetolactate synthase I\/II\/III large subunit [EC:2.2.1.6]" }, { "name":"R0135_17065 acetolactate synthase 3 large subunit\tK01652 E2.2.1.6L; acetolactate synthase I\/II\/III large subunit [EC:2.2.1.6]" }, { "name":"R0135_17070 ilvN; (GenBank) acetolactate synthase small subunit\tK01653 E2.2.1.6S; acetolactate synthase I\/III small subunit [EC:2.2.1.6]" } ] }, { "name":"00660 C5-Branched dibasic acid metabolism [PATH:cvb00660]", "children":[ { "name":"R0135_01660 5-guanidino-2-oxopentanoate decarboxylase\tK01652 E2.2.1.6L; acetolactate synthase I\/II\/III large subunit [EC:2.2.1.6]" }, { "name":"R0135_04490 acetolactate synthase large subunit\tK01652 E2.2.1.6L; acetolactate synthase I\/II\/III large subunit [EC:2.2.1.6]" }, { "name":"R0135_04820 ilvB; (GenBank) biosynthetic-type acetolactate synthase large subunit\tK01652 E2.2.1.6L; acetolactate synthase I\/II\/III large subunit [EC:2.2.1.6]" }, { "name":"R0135_05855 acetolactate synthase large subunit\tK01652 E2.2.1.6L; acetolactate synthase I\/II\/III large subunit [EC:2.2.1.6]" }, { "name":"R0135_17065 acetolactate synthase 3 large subunit\tK01652 E2.2.1.6L; acetolactate synthase I\/II\/III large subunit [EC:2.2.1.6]" }, { "name":"R0135_17070 ilvN; (GenBank) acetolactate synthase small subunit\tK01653 E2.2.1.6S; acetolactate synthase I\/III small subunit [EC:2.2.1.6]" }, { "name":"R0135_02275 sucC; (GenBank) ADP-forming succinate--CoA ligase subunit beta\tK01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]" }, { "name":"R0135_02280 sucD; (GenBank) succinate--CoA ligase subunit alpha\tK01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]" }, { "name":"R0135_03900 leuC; (GenBank) 3-isopropylmalate dehydratase large subunit\tK01703 leuC; 3-isopropylmalate\/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35]" }, { "name":"R0135_03895 leuD; (GenBank) 3-isopropylmalate dehydratase small subunit\tK01704 leuD; 3-isopropylmalate\/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35]" }, { "name":"R0135_03890 leuB; (GenBank) 3-isopropylmalate dehydrogenase\tK00052 leuB; 3-isopropylmalate dehydrogenase [EC:1.1.1.85]" } ] }, { "name":"00562 Inositol phosphate metabolism [PATH:cvb00562]", "children":[ { "name":"R0135_00950 inositol monophosphatase family protein\tK01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25]" }, { "name":"R0135_02860 inositol monophosphatase family protein\tK01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25]" }, { "name":"R0135_10955 CoA-acylating methylmalonate-semialdehyde dehydrogenase\tK00140 mmsA; malonate-semialdehyde dehydrogenase (acetylating) \/ methylmalonate-semialdehyde dehydrogenase [EC:1.2.1.18 1.2.1.27]" }, { "name":"R0135_08715 tpiA; (GenBank) triose-phosphate isomerase\tK01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]" } ] }, { "name":"00566 Sulfoquinovose metabolism", "children":[ { "name":"R0135_02115 malate dehydrogenase\tK00024 mdh; malate dehydrogenase [EC:1.1.1.37]" } ] } ] }, { "name":"09102 Energy metabolism", "children":[ { "name":"00190 Oxidative phosphorylation [PATH:cvb00190]", "children":[ { "name":"R0135_02250 sdhA; (GenBank) succinate dehydrogenase flavoprotein subunit\tK00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]" }, { "name":"R0135_02255 succinate dehydrogenase iron-sulfur subunit\tK00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]" }, { "name":"R0135_02240 sdhC; (GenBank) succinate dehydrogenase, cytochrome b556 subunit\tK00241 sdhC; succinate dehydrogenase cytochrome b subunit" }, { "name":"R0135_02245 sdhD; (GenBank) succinate dehydrogenase, hydrophobic membrane anchor protein\tK00242 sdhD; succinate dehydrogenase membrane anchor subunit" }, { "name":"R0135_08265 fumarate reductase flavoprotein subunit\tK00233 frdA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1 7.1.1.12]" }, { "name":"R0135_08260 fumarate reductase iron-sulfur subunit\tK25995 frdB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1 7.1.1.12]" }, { "name":"R0135_08270 fumarate reductase cytochrome b subunit\tK25996 frdC; succinate dehydrogenase subunit C" }, { "name":"R0135_07310 petA; (GenBank) ubiquinol-cytochrome c reductase iron-sulfur subunit\tK00411 UQCRFS1; ubiquinol-cytochrome c reductase iron-sulfur subunit [EC:7.1.1.8]" }, { "name":"R0135_07305 ubiquinol-cytochrome c reductase\tK00412 CYTB; ubiquinol-cytochrome c reductase cytochrome b subunit" }, { "name":"R0135_11985 cyoE; (GenBank) heme o synthase\tK02257 COX10; heme o synthase [EC:2.5.1.141]" }, { "name":"R0135_11965 cytochrome c oxidase subunit 3\tK02276 coxC; cytochrome c oxidase subunit III [EC:7.1.1.9]" }, { "name":"R0135_11955 ctaD; (GenBank) cytochrome c oxidase subunit I\tK02274 coxA; cytochrome c oxidase subunit I [EC:7.1.1.9]" }, { "name":"R0135_11950 coxB; (GenBank) cytochrome c oxidase subunit II\tK02275 coxB; cytochrome c oxidase subunit II [EC:7.1.1.9]" }, { "name":"R0135_11960 cytochrome c oxidase assembly protein\tK02258 COX11; cytochrome c oxidase assembly protein subunit 11" }, { "name":"R0135_08310 COX15\/CtaA family protein\tK02259 COX15; heme a synthase [EC:1.17.99.9]" }, { "name":"R0135_01725 ccoN; (GenBank) cytochrome-c oxidase, cbb3-type subunit I\tK00404 ccoN; cytochrome c oxidase cbb3-type subunit I [EC:7.1.1.9]" }, { "name":"R0135_01720 ccoO; (GenBank) cytochrome-c oxidase, cbb3-type subunit II\tK00405 ccoO; cytochrome c oxidase cbb3-type subunit II" }, { "name":"R0135_01715 cbb3-type cytochrome c oxidase subunit 3\tK00407 ccoQ; cytochrome c oxidase cbb3-type subunit IV" }, { "name":"R0135_01710 ccoP; (GenBank) cytochrome-c oxidase, cbb3-type subunit III\tK00406 ccoP; cytochrome c oxidase cbb3-type subunit III" }, { "name":"R0135_06120 cytochrome ubiquinol oxidase subunit I\tK00425 cydA; cytochrome bd ubiquinol oxidase subunit I [EC:7.1.1.7]" }, { "name":"R0135_06125 cydB; (GenBank) cytochrome d ubiquinol oxidase subunit II\tK00426 cydB; cytochrome bd ubiquinol oxidase subunit II [EC:7.1.1.7]" }, { "name":"R0135_11770 c-type cytochrome\tK08738 CYC; cytochrome c" }, { "name":"R0135_11670 atpA; (GenBank) F0F1 ATP synthase subunit alpha\tK02111 ATPF1A; F-type H+\/Na+-transporting ATPase subunit alpha [EC:7.1.2.2 7.2.2.1]" }, { "name":"R0135_15285 alternate F1F0 ATPase, F1 subunit alpha\tK02111 ATPF1A; F-type H+\/Na+-transporting ATPase subunit alpha [EC:7.1.2.2 7.2.2.1]" }, { "name":"R0135_11660 atpD; (GenBank) F0F1 ATP synthase subunit beta\tK02112 ATPF1B; F-type H+\/Na+-transporting ATPase subunit beta [EC:7.1.2.2 7.2.2.1]" }, { "name":"R0135_15250 atpD; (GenBank) F0F1 ATP synthase subunit beta\tK02112 ATPF1B; F-type H+\/Na+-transporting ATPase subunit beta [EC:7.1.2.2 7.2.2.1]" }, { "name":"R0135_11665 atpG; (GenBank) F0F1 ATP synthase subunit gamma\tK02115 ATPF1G; F-type H+-transporting ATPase subunit gamma" }, { "name":"R0135_15290 F0F1 ATP synthase subunit gamma\tK02115 ATPF1G; F-type H+-transporting ATPase subunit gamma" }, { "name":"R0135_11675 F0F1 ATP synthase subunit delta\tK02113 ATPF1D; F-type H+-transporting ATPase subunit delta" }, { "name":"R0135_11655 F0F1 ATP synthase subunit epsilon\tK02114 ATPF1E; F-type H+-transporting ATPase subunit epsilon" }, { "name":"R0135_15255 F0F1 ATP synthase subunit epsilon\tK02114 ATPF1E; F-type H+-transporting ATPase subunit epsilon" }, { "name":"R0135_11690 atpB; (GenBank) F0F1 ATP synthase subunit A\tK02108 ATPF0A; F-type H+-transporting ATPase subunit a" }, { "name":"R0135_15270 F0F1 ATP synthase subunit A\tK02108 ATPF0A; F-type H+-transporting ATPase subunit a" }, { "name":"R0135_11680 F0F1 ATP synthase subunit B\tK02109 ATPF0B; F-type H+-transporting ATPase subunit b" }, { "name":"R0135_15280 hypothetical protein\tK02109 ATPF0B; F-type H+-transporting ATPase subunit b" }, { "name":"R0135_11685 atpE; (GenBank) F0F1 ATP synthase subunit C\tK02110 ATPF0C; F-type H+-transporting ATPase subunit c" }, { "name":"R0135_15275 F0F1 ATP synthase subunit C\tK02110 ATPF0C; F-type H+-transporting ATPase subunit c" }, { "name":"R0135_08595 inorganic pyrophosphatase\tK01507 ppa; inorganic pyrophosphatase [EC:3.6.1.1]" }, { "name":"R0135_02020 ppk1; (GenBank) polyphosphate kinase 1\tK00937 ppk1; polyphosphate kinase [EC:2.7.4.1]" }, { "name":"R0135_00525 ppk2; (GenBank) polyphosphate kinase 2\tK22468 ppk2; polyphosphate kinase [EC:2.7.4.34]" }, { "name":"R0135_13270 ppk2; (GenBank) polyphosphate kinase 2\tK22468 ppk2; polyphosphate kinase [EC:2.7.4.34]" } ] }, { "name":"00195 Photosynthesis" }, { "name":"00196 Photosynthesis - antenna proteins" }, { "name":"00710 Carbon fixation by Calvin cycle [PATH:cvb00710]", "children":[ { "name":"R0135_11295 phosphoglycerate kinase\tK00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]" }, { "name":"R0135_03490 glyceraldehyde-3-phosphate dehydrogenase\tK00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]" }, { "name":"R0135_05170 gap; (GenBank) type I glyceraldehyde-3-phosphate dehydrogenase\tK00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]" }, { "name":"R0135_05470 gap; (GenBank) type I glyceraldehyde-3-phosphate dehydrogenase\tK00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]" }, { "name":"R0135_05475 glyceraldehyde 3-phosphate dehydrogenase NAD-binding domain-containing protein\tK00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]" }, { "name":"R0135_00840 class I fructose-bisphosphate aldolase\tK01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]" }, { "name":"R0135_11290 fba; (GenBank) class II fructose-bisphosphate aldolase\tK01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]" }, { "name":"R0135_11305 tkt; (GenBank) transketolase\tK00615 E2.2.1.1; transketolase [EC:2.2.1.1]" }, { "name":"R0135_11235 rpiA; (GenBank) ribose-5-phosphate isomerase RpiA\tK01807 rpiA; ribose 5-phosphate isomerase A [EC:5.3.1.6]" }, { "name":"R0135_08715 tpiA; (GenBank) triose-phosphate isomerase\tK01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]" }, { "name":"R0135_14515 rpe; (GenBank) ribulose-phosphate 3-epimerase\tK01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1]" }, { "name":"R0135_04630 tal; (GenBank) transaldolase\tK00616 TALDO1; transaldolase [EC:2.2.1.2]" }, { "name":"R0135_05160 ppc; (GenBank) phosphoenolpyruvate carboxylase\tK01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31]" }, { "name":"R0135_09500 phosphoenolpyruvate carboxykinase\tK01610 pckA; phosphoenolpyruvate carboxykinase (ATP) [EC:4.1.1.49]" }, { "name":"R0135_05285 ppdK; (GenBank) pyruvate, phosphate dikinase\tK01006 ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1]" }, { "name":"R0135_05210 NADP-dependent malic enzyme\tK00029 maeB; malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+) [EC:1.1.1.40]" }, { "name":"R0135_02115 malate dehydrogenase\tK00024 mdh; malate dehydrogenase [EC:1.1.1.37]" } ] }, { "name":"00720 Other carbon fixation pathways [PATH:cvb00720]", "children":[ { "name":"R0135_06250 nifJ; (GenBank) pyruvate:ferredoxin (flavodoxin) oxidoreductase\tK03737 por; pyruvate-ferredoxin\/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.8.1]" }, { "name":"R0135_15350 ppsA; (GenBank) phosphoenolpyruvate synthase\tK01007 pps; pyruvate, water dikinase [EC:2.7.9.2]" }, { "name":"R0135_05285 ppdK; (GenBank) pyruvate, phosphate dikinase\tK01006 ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1]" }, { "name":"R0135_05160 ppc; (GenBank) phosphoenolpyruvate carboxylase\tK01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31]" }, { "name":"R0135_02115 malate dehydrogenase\tK00024 mdh; malate dehydrogenase [EC:1.1.1.37]" }, { "name":"R0135_16950 fumarate hydratase\tK01676 E4.2.1.2A; fumarate hydratase, class I [EC:4.2.1.2]" }, { "name":"R0135_02250 sdhA; (GenBank) succinate dehydrogenase flavoprotein subunit\tK00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]" }, { "name":"R0135_02255 succinate dehydrogenase iron-sulfur subunit\tK00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]" }, { "name":"R0135_02240 sdhC; (GenBank) succinate dehydrogenase, cytochrome b556 subunit\tK00241 sdhC; succinate dehydrogenase cytochrome b subunit" }, { "name":"R0135_02245 sdhD; (GenBank) succinate dehydrogenase, hydrophobic membrane anchor protein\tK00242 sdhD; succinate dehydrogenase membrane anchor subunit" }, { "name":"R0135_08265 fumarate reductase flavoprotein subunit\tK00233 frdA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1 7.1.1.12]" }, { "name":"R0135_08260 fumarate reductase iron-sulfur subunit\tK25995 frdB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1 7.1.1.12]" }, { "name":"R0135_08270 fumarate reductase cytochrome b subunit\tK25996 frdC; succinate dehydrogenase subunit C" }, { "name":"R0135_02280 sucD; (GenBank) succinate--CoA ligase subunit alpha\tK01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]" }, { "name":"R0135_02275 sucC; (GenBank) ADP-forming succinate--CoA ligase subunit beta\tK01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]" }, { "name":"R0135_00330 acetyl-CoA C-acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" }, { "name":"R0135_03970 acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" }, { "name":"R0135_04435 acetyl-CoA C-acyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" }, { "name":"R0135_05075 acetyl-CoA C-acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" }, { "name":"R0135_11080 acetyl-CoA C-acyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" }, { "name":"R0135_11085 acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" }, { "name":"R0135_08105 2-oxoacid:acceptor oxidoreductase subunit alpha\tK00174 korA; 2-oxoglutarate\/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]" }, { "name":"R0135_10165 2-oxoacid:acceptor oxidoreductase subunit alpha\tK00174 korA; 2-oxoglutarate\/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]" }, { "name":"R0135_08100 2-oxoacid:ferredoxin oxidoreductase subunit beta\tK00175 korB; 2-oxoglutarate\/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]" }, { "name":"R0135_10160 2-oxoacid:ferredoxin oxidoreductase subunit beta\tK00175 korB; 2-oxoglutarate\/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]" }, { "name":"R0135_02625 icd; (GenBank) NADP-dependent isocitrate dehydrogenase\tK00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]" }, { "name":"R0135_04930 isocitrate\/isopropylmalate family dehydrogenase\tK00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]" }, { "name":"R0135_03670 acnB; (GenBank) bifunctional aconitate hydratase 2\/2-methylisocitrate dehydratase\tK01682 acnB; aconitate hydratase 2 \/ 2-methylisocitrate dehydratase [EC:4.2.1.3 4.2.1.99]" }, { "name":"R0135_05410 acetyl-CoA carboxylase carboxyltransferase subunit alpha\tK01962 accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15]" }, { "name":"R0135_14585 accB; (GenBank) acetyl-CoA carboxylase biotin carboxyl carrier protein\tK02160 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein" }, { "name":"R0135_14580 accC; (GenBank) acetyl-CoA carboxylase biotin carboxylase subunit\tK01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14]" }, { "name":"R0135_02565 mce; (GenBank) methylmalonyl-CoA epimerase\tK05606 MCEE; methylmalonyl-CoA\/ethylmalonyl-CoA epimerase [EC:5.1.99.1]" }, { "name":"R0135_02570 scpA; (GenBank) methylmalonyl-CoA mutase\tK01847 MUT; methylmalonyl-CoA mutase [EC:5.4.99.2]" }, { "name":"R0135_16420 acyl-CoA mutase large subunit family protein\tK01848 E5.4.99.2A; methylmalonyl-CoA mutase, N-terminal domain [EC:5.4.99.2]" }, { "name":"R0135_16425 cobalamin-dependent protein\tK01849 E5.4.99.2B; methylmalonyl-CoA mutase, C-terminal domain [EC:5.4.99.2]" }, { "name":"R0135_04840 folD; (GenBank) bifunctional methylenetetrahydrofolate dehydrogenase\/methenyltetrahydrofolate cyclohydrolase FolD\tK01491 folD; methylenetetrahydrofolate dehydrogenase (NADP+) \/ methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9]" }, { "name":"R0135_11325 metF; (GenBank) methylenetetrahydrofolate reductase [NAD(P)H]\tK00297 metF; methylenetetrahydrofolate reductase (NADH) [EC:1.5.1.54]" }, { "name":"R0135_08655 acs; (GenBank) acetate--CoA ligase\tK01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]" } ] }, { "name":"00680 Methane metabolism [PATH:cvb00680]", "children":[ { "name":"R0135_00320 S-(hydroxymethyl)glutathione dehydrogenase\/class III alcohol dehydrogenase\tK00121 frmA; S-(hydroxymethyl)glutathione dehydrogenase \/ alcohol dehydrogenase [EC:1.1.1.284 1.1.1.1]" }, { "name":"R0135_00325 fghA; (GenBank) S-formylglutathione hydrolase\tK01070 frmB; S-formylglutathione hydrolase [EC:3.1.2.12]" }, { "name":"R0135_15430 glyA; (GenBank) serine hydroxymethyltransferase\tK00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]" }, { "name":"R0135_03940 alanine--glyoxylate aminotransferase family protein\tK00830 AGXT; alanine-glyoxylate transaminase \/ serine-glyoxylate transaminase \/ serine-pyruvate transaminase [EC:2.6.1.44 2.6.1.45 2.6.1.51]" }, { "name":"R0135_05390 eno; (GenBank) phosphopyruvate hydratase\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]" }, { "name":"R0135_05160 ppc; (GenBank) phosphoenolpyruvate carboxylase\tK01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31]" }, { "name":"R0135_02115 malate dehydrogenase\tK00024 mdh; malate dehydrogenase [EC:1.1.1.37]" }, { "name":"R0135_00840 class I fructose-bisphosphate aldolase\tK01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]" }, { "name":"R0135_11290 fba; (GenBank) class II fructose-bisphosphate aldolase\tK01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]" }, { "name":"R0135_08590 6-phosphofructokinase\tK21071 pfk; ATP-dependent phosphofructokinase \/ diphosphate-dependent phosphofructokinase [EC:2.7.1.11 2.7.1.90]" }, { "name":"R0135_13150 methylamine dehydrogenase light chain\tK15228 mauA; methylamine dehydrogenase light chain [EC:1.4.9.1]" }, { "name":"R0135_13165 amine dehydrogenase large subunit\tK15229 mauB; methylamine dehydrogenase heavy chain [EC:1.4.9.1]" }, { "name":"R0135_08655 acs; (GenBank) acetate--CoA ligase\tK01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]" }, { "name":"R0135_15350 ppsA; (GenBank) phosphoenolpyruvate synthase\tK01007 pps; pyruvate, water dikinase [EC:2.7.9.2]" }, { "name":"R0135_12395 gpmI; (GenBank) 2,3-bisphosphoglycerate-independent phosphoglycerate mutase\tK15633 gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12]" }, { "name":"R0135_11245 serA; (GenBank) phosphoglycerate dehydrogenase\tK00058 serA; D-3-phosphoglycerate dehydrogenase \/ 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]" }, { "name":"R0135_13440 phosphoglycerate dehydrogenase\tK00058 serA; D-3-phosphoglycerate dehydrogenase \/ 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]" }, { "name":"R0135_06810 serC; (GenBank) 3-phosphoserine\/phosphohydroxythreonine transaminase\tK00831 serC; phosphoserine aminotransferase [EC:2.6.1.52]" }, { "name":"R0135_12485 serB; (GenBank) phosphoserine phosphatase SerB\tK01079 serB; phosphoserine phosphatase [EC:3.1.3.3]" } ] }, { "name":"00910 Nitrogen metabolism [PATH:cvb00910]", "children":[ { "name":"R0135_12330 acetamidase\/formamidase family protein\tK01455 fmdA; formamidase [EC:3.5.1.49]" }, { "name":"R0135_01455 nitronate monooxygenase family protein\tK00459 ncd2; nitronate monooxygenase [EC:1.13.12.16]" }, { "name":"R0135_06655 nitronate monooxygenase\tK00459 ncd2; nitronate monooxygenase [EC:1.13.12.16]" }, { "name":"R0135_11095 nitronate monooxygenase\tK00459 ncd2; nitronate monooxygenase [EC:1.13.12.16]" }, { "name":"R0135_04505 carbon-nitrogen hydrolase family protein\tK01501 E3.5.5.1; nitrilase [EC:3.5.5.1]" }, { "name":"R0135_04195 NAD-glutamate dehydrogenase\tK15371 GDH2; glutamate dehydrogenase [EC:1.4.1.2]" }, { "name":"R0135_08950 glutamine synthetase family protein\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]" }, { "name":"R0135_09260 glutamine synthetase family protein\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]" }, { "name":"R0135_10760 glutamine synthetase family protein\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]" }, { "name":"R0135_12435 glnA; (GenBank) glutamate--ammonia ligase\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]" }, { "name":"R0135_12885 glutamine synthetase family protein\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]" }, { "name":"R0135_12730 gltB; (GenBank) glutamate synthase large subunit\tK00265 gltB; glutamate synthase (NADPH) large chain [EC:1.4.1.13]" }, { "name":"R0135_12735 FAD-dependent oxidoreductase\tK00266 gltD; glutamate synthase (NADPH) small chain [EC:1.4.1.13]" }, { "name":"R0135_07055 can; (GenBank) carbonate dehydratase\tK01673 cynT; carbonic anhydrase [EC:4.2.1.1]" } ] }, { "name":"00920 Sulfur metabolism [PATH:cvb00920]", "children":[ { "name":"R0135_16000 tauD; (GenBank) taurine dioxygenase\tK03119 tauD; taurine dioxygenase [EC:1.14.11.17]" }, { "name":"R0135_07045 sat; (GenBank) sulfate adenylyltransferase\tK00958 sat; sulfate adenylyltransferase [EC:2.7.7.4]" }, { "name":"R0135_07050 cysC; (GenBank) adenylyl-sulfate kinase\tK00860 cysC; adenylylsulfate kinase [EC:2.7.1.25]" }, { "name":"R0135_15545 cysQ; (GenBank) 3'(2'),5'-bisphosphate nucleotidase CysQ\tK01082 cysQ; 3'(2'), 5'-bisphosphate nucleotidase [EC:3.1.3.7]" }, { "name":"R0135_10380 phosphoadenylyl-sulfate reductase\tK00390 cysH; phosphoadenosine phosphosulfate reductase [EC:1.8.4.8 1.8.4.10]" }, { "name":"R0135_16530 phosphoadenosine phosphosulfate reductase family protein\tK00390 cysH; phosphoadenosine phosphosulfate reductase [EC:1.8.4.8 1.8.4.10]" }, { "name":"R0135_12975 soxA; (GenBank) sulfur oxidation c-type cytochrome SoxA\tK17222 soxA; L-cysteine S-thiosulfotransferase [EC:2.8.5.2]" }, { "name":"R0135_12960 soxX; (GenBank) sulfur oxidation c-type cytochrome SoxX\tK17223 soxX; L-cysteine S-thiosulfotransferase [EC:2.8.5.2]" }, { "name":"R0135_12965 soxY; (GenBank) thiosulfate oxidation carrier protein SoxY\tK17226 soxY; sulfur-oxidizing protein SoxY" }, { "name":"R0135_12970 soxZ; (GenBank) thiosulfate oxidation carrier complex protein SoxZ\tK17227 soxZ; sulfur-oxidizing protein SoxZ" }, { "name":"R0135_12985 soxB; (GenBank) thiosulfohydrolase SoxB\tK17224 soxB; S-sulfosulfanyl-L-cysteine sulfohydrolase [EC:3.1.6.20]" }, { "name":"R0135_12950 soxC; (GenBank) sulfite dehydrogenase\tK17225 soxC; sulfane dehydrogenase subunit SoxC" }, { "name":"R0135_12955 c-type cytochrome\tK22622 soxD; S-disulfanyl-L-cysteine oxidoreductase SoxD [EC:1.8.2.6]" }, { "name":"R0135_03000 nitrite\/sulfite reductase\tK00381 cysI; sulfite reductase (NADPH) hemoprotein beta-component [EC:1.8.1.2]" }, { "name":"R0135_02895 TIGR01244 family sulfur transferase\tK17218 sqr; sulfide:quinone oxidoreductase [EC:1.8.5.4]" }, { "name":"R0135_06350 FAD\/NAD(P)-binding oxidoreductase\tK17218 sqr; sulfide:quinone oxidoreductase [EC:1.8.5.4]" }, { "name":"R0135_06890 sulfurtransferase\tK01011 TST; thiosulfate\/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2]" }, { "name":"R0135_13775 rhodanese-like domain-containing protein\tK03972 pspE; thiosulfate sulfurtransferase [EC:2.8.1.1]" }, { "name":"R0135_12745 cysE; (GenBank) serine O-acetyltransferase\tK00640 cysE; serine O-acetyltransferase [EC:2.3.1.30]" }, { "name":"R0135_13230 cysK; (GenBank) cysteine synthase A\tK01738 cysK; cysteine synthase [EC:2.5.1.47]" }, { "name":"R0135_01375 alpha\/beta fold hydrolase\tK00641 metX; homoserine O-acetyltransferase\/O-succinyltransferase [EC:2.3.1.31 2.3.1.46]" }, { "name":"R0135_11380 homoserine O-acetyltransferase\tK00641 metX; homoserine O-acetyltransferase\/O-succinyltransferase [EC:2.3.1.31 2.3.1.46]" }, { "name":"R0135_03830 O-succinylhomoserine sulfhydrylase\tK10764 metZ; O-succinylhomoserine sulfhydrylase [EC:2.5.1.-]" }, { "name":"R0135_16790 long-chain-fatty-acid--CoA ligase\tK20034 dmdB; 3-(methylthio)propionyl---CoA ligase [EC:6.2.1.44]" }, { "name":"R0135_07115 acyl-CoA dehydrogenase\tK20035 dmdC; 3-(methylsulfanyl)propanoyl-CoA dehydrogenase [EC:1.3.99.41]" }, { "name":"R0135_12790 acyl-CoA dehydrogenase C-terminal domain-containing protein\tK20035 dmdC; 3-(methylsulfanyl)propanoyl-CoA dehydrogenase [EC:1.3.99.41]" } ] } ] }, { "name":"09103 Lipid metabolism", "children":[ { "name":"00061 Fatty acid biosynthesis [PATH:cvb00061]", "children":[ { "name":"R0135_05410 acetyl-CoA carboxylase carboxyltransferase subunit alpha\tK01962 accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15]" }, { "name":"R0135_14585 accB; (GenBank) acetyl-CoA carboxylase biotin carboxyl carrier protein\tK02160 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein" }, { "name":"R0135_14580 accC; (GenBank) acetyl-CoA carboxylase biotin carboxylase subunit\tK01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14]" }, { "name":"R0135_04855 acyl-CoA synthetase\tK18660 ACSF3; malonyl-CoA\/methylmalonyl-CoA synthetase [EC:6.2.1.76 6.2.1.-]" }, { "name":"R0135_03105 acpP; (GenBank) acyl carrier protein\tK02078 acpP; acyl carrier protein" }, { "name":"R0135_03115 fabD; (GenBank) ACP S-malonyltransferase\tK00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]" }, { "name":"R0135_04425 beta-ketoacyl synthase\tK18473 fabY; acetoacetyl-[acyl-carrier protein] synthase [EC:2.3.1.180]" }, { "name":"R0135_15900 fabB; (GenBank) beta-ketoacyl-ACP synthase I\tK00647 fabB; 3-oxoacyl-[acyl-carrier-protein] synthase I [EC:2.3.1.41]" }, { "name":"R0135_03100 fabF; (GenBank) beta-ketoacyl-ACP synthase II\tK09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179]" }, { "name":"R0135_03110 fabG; (GenBank) 3-oxoacyl-ACP reductase FabG\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]" }, { "name":"R0135_04290 SDR family oxidoreductase\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]" }, { "name":"R0135_08120 SDR family oxidoreductase\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]" }, { "name":"R0135_10580 SDR family oxidoreductase\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]" }, { "name":"R0135_15905 fabA; (GenBank) 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabA\tK01716 fabA; 3-hydroxyacyl-[acyl-carrier protein] dehydratase \/ trans-2-decenoyl-[acyl-carrier protein] isomerase [EC:4.2.1.59 5.3.3.14]" }, { "name":"R0135_00080 fabZ; (GenBank) 3-hydroxyacyl-ACP dehydratase FabZ\tK02372 fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:4.2.1.59]" }, { "name":"R0135_05290 nitronate monooxygenase\tK02371 fabK; enoyl-[acyl-carrier protein] reductase II [EC:1.3.1.9]" }, { "name":"R0135_16780 trans-2-enoyl-CoA reductase family protein\tK00209 fabV; enoyl-[acyl-carrier protein] reductase \/ trans-2-enoyl-CoA reductase (NAD+) [EC:1.3.1.9 1.3.1.44]" }, { "name":"R0135_05490 AMP-binding protein\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]" }, { "name":"R0135_05640 AMP-binding protein\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]" } ] }, { "name":"00062 Fatty acid elongation" }, { "name":"00071 Fatty acid degradation [PATH:cvb00071]", "children":[ { "name":"R0135_00330 acetyl-CoA C-acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" }, { "name":"R0135_03970 acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" }, { "name":"R0135_04435 acetyl-CoA C-acyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" }, { "name":"R0135_05075 acetyl-CoA C-acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" }, { "name":"R0135_11080 acetyl-CoA C-acyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" }, { "name":"R0135_11085 acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" }, { "name":"R0135_08785 acetyl-CoA C-acyltransferase\tK00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16]" }, { "name":"R0135_09400 fadA; (GenBank) acetyl-CoA C-acyltransferase FadA\tK00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16]" }, { "name":"R0135_09395 fadB; (GenBank) fatty acid oxidation complex subunit alpha FadB\tK01825 fadB; 3-hydroxyacyl-CoA dehydrogenase \/ enoyl-CoA hydratase \/ 3-hydroxybutyryl-CoA epimerase \/ enoyl-CoA isomerase [EC:1.1.1.35 4.2.1.17 5.1.2.3 5.3.3.8]" }, { "name":"R0135_00335 3-hydroxyacyl-CoA dehydrogenase NAD-binding domain-containing protein\tK01782 fadJ; 3-hydroxyacyl-CoA dehydrogenase \/ enoyl-CoA hydratase \/ 3-hydroxybutyryl-CoA epimerase [EC:1.1.1.35 4.2.1.17 5.1.2.3]" }, { "name":"R0135_05070 acyl-CoA dehydrogenase family protein\tK00249 ACADM; acyl-CoA dehydrogenase [EC:1.3.8.7]" }, { "name":"R0135_08090 acyl-CoA dehydrogenase family protein\tK00249 ACADM; acyl-CoA dehydrogenase [EC:1.3.8.7]" }, { "name":"R0135_08800 acyl-CoA dehydrogenase family protein\tK00249 ACADM; acyl-CoA dehydrogenase [EC:1.3.8.7]" }, { "name":"R0135_16005 acyl-CoA dehydrogenase family protein\tK00249 ACADM; acyl-CoA dehydrogenase [EC:1.3.8.7]" }, { "name":"R0135_01560 acyl-CoA dehydrogenase family protein\tK00255 ACADL; long-chain-acyl-CoA dehydrogenase [EC:1.3.8.8]" }, { "name":"R0135_01940 acyl-CoA dehydrogenase family protein\tK00255 ACADL; long-chain-acyl-CoA dehydrogenase [EC:1.3.8.8]" }, { "name":"R0135_04285 acyl-CoA dehydrogenase family protein\tK00255 ACADL; long-chain-acyl-CoA dehydrogenase [EC:1.3.8.8]" }, { "name":"R0135_10745 acyl-CoA dehydrogenase\tK00252 GCDH; glutaryl-CoA dehydrogenase [EC:1.3.8.6]" }, { "name":"R0135_05490 AMP-binding protein\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]" }, { "name":"R0135_05640 AMP-binding protein\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]" }, { "name":"R0135_11545 FAD-dependent oxidoreductase\tK05297 rubB; rubredoxin---NAD+ reductase [EC:1.18.1.1]" }, { "name":"R0135_00320 S-(hydroxymethyl)glutathione dehydrogenase\/class III alcohol dehydrogenase\tK00121 frmA; S-(hydroxymethyl)glutathione dehydrogenase \/ alcohol dehydrogenase [EC:1.1.1.284 1.1.1.1]" }, { "name":"R0135_01945 aldehyde dehydrogenase family protein\tK00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]" } ] }, { "name":"00073 Cutin, suberine and wax biosynthesis [PATH:cvb00073]", "children":[ { "name":"R0135_10700 SDR family oxidoreductase\tK28138 acrB; alcohol-forming fatty acyl-CoA reductase [EC:1.2.1.84]" }, { "name":"R0135_04765 hydroxymethylglutaryl-CoA reductase\tK28139 fcrA; alcohol-forming fatty acyl-CoA reductase [EC:1.2.1.84]" }, { "name":"R0135_02035 wax ester\/triacylglycerol synthase family O-acyltransferase\tK00635 tgs; wax synthase \/ diacylglycerol O-acyltransferase [EC:2.3.1.75 2.3.1.20]" }, { "name":"R0135_10170 wax ester\/triacylglycerol synthase family O-acyltransferase\tK00635 tgs; wax synthase \/ diacylglycerol O-acyltransferase [EC:2.3.1.75 2.3.1.20]" }, { "name":"R0135_14310 wax ester\/triacylglycerol synthase family O-acyltransferase\tK00635 tgs; wax synthase \/ diacylglycerol O-acyltransferase [EC:2.3.1.75 2.3.1.20]" } ] }, { "name":"00074 Mycolic acid biosynthesis [PATH:cvb00074]", "children":[ { "name":"R0135_01830 acpS; (GenBank) holo-ACP synthase\tK00997 acpS; holo-[acyl-carrier protein] synthase [EC:2.7.8.7]" }, { "name":"R0135_03105 acpP; (GenBank) acyl carrier protein\tK02078 acpP; acyl carrier protein" }, { "name":"R0135_03115 fabD; (GenBank) ACP S-malonyltransferase\tK00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]" } ] }, { "name":"00100 Steroid biosynthesis" }, { "name":"00120 Primary bile acid biosynthesis" }, { "name":"00121 Secondary bile acid biosynthesis" }, { "name":"00140 Steroid hormone biosynthesis" }, { "name":"00561 Glycerolipid metabolism [PATH:cvb00561]", "children":[ { "name":"R0135_16760 hypothetical protein\tK15918 GLYK; D-glycerate 3-kinase [EC:2.7.1.31]" }, { "name":"R0135_01945 aldehyde dehydrogenase family protein\tK00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]" }, { "name":"R0135_07990 glycerol dehydrogenase\tK00005 gldA; glycerol dehydrogenase [EC:1.1.1.6]" }, { "name":"R0135_01950 glpK; (GenBank) glycerol kinase GlpK\tK00864 glpK; glycerol kinase [EC:2.7.1.30]" }, { "name":"R0135_10175 glycerol-3-phosphate 1-O-acyltransferase\tK00631 plsB; glycerol-3-phosphate O-acyltransferase [EC:2.3.1.15]" }, { "name":"R0135_03990 lysophospholipid acyltransferase family protein\tK00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]" }, { "name":"R0135_02830 diacylglycerol kinase\tK00901 dgkA; diacylglycerol kinase (ATP) [EC:2.7.1.107]" }, { "name":"R0135_02035 wax ester\/triacylglycerol synthase family O-acyltransferase\tK00635 tgs; wax synthase \/ diacylglycerol O-acyltransferase [EC:2.3.1.75 2.3.1.20]" }, { "name":"R0135_10170 wax ester\/triacylglycerol synthase family O-acyltransferase\tK00635 tgs; wax synthase \/ diacylglycerol O-acyltransferase [EC:2.3.1.75 2.3.1.20]" }, { "name":"R0135_14310 wax ester\/triacylglycerol synthase family O-acyltransferase\tK00635 tgs; wax synthase \/ diacylglycerol O-acyltransferase [EC:2.3.1.75 2.3.1.20]" }, { "name":"R0135_12095 alpha\/beta hydrolase\tK01054 MGLL; acylglycerol lipase [EC:3.1.1.23]" }, { "name":"R0135_05115 alpha-galactosidase\tK07407 E3.2.1.22B; alpha-galactosidase [EC:3.2.1.22]" } ] }, { "name":"00564 Glycerophospholipid metabolism [PATH:cvb00564]", "children":[ { "name":"R0135_10720 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase\tK00057 gpsA; glycerol-3-phosphate dehydrogenase (NAD(P)+) [EC:1.1.1.94]" }, { "name":"R0135_10780 glycerol-3-phosphate dehydrogenase\/oxidase\tK00111 glpA; glycerol-3-phosphate dehydrogenase [EC:1.1.5.3]" }, { "name":"R0135_10175 glycerol-3-phosphate 1-O-acyltransferase\tK00631 plsB; glycerol-3-phosphate O-acyltransferase [EC:2.3.1.15]" }, { "name":"R0135_03990 lysophospholipid acyltransferase family protein\tK00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]" }, { "name":"R0135_02830 diacylglycerol kinase\tK00901 dgkA; diacylglycerol kinase (ATP) [EC:2.7.1.107]" }, { "name":"R0135_06670 phospholipase A\tK01058 pldA; phospholipase A1\/A2 [EC:3.1.1.32 3.1.1.4]" }, { "name":"R0135_11035 glpQ; (GenBank) glycerophosphodiester phosphodiesterase\tK01126 E3.1.4.46; glycerophosphoryl diester phosphodiesterase [EC:3.1.4.46]" }, { "name":"R0135_00050 phosphatidate cytidylyltransferase\tK00981 E2.7.7.41; phosphatidate cytidylyltransferase [EC:2.7.7.41]" }, { "name":"R0135_17085 pssA; (GenBank) CDP-diacylglycerol--serine O-phosphatidyltransferase\tK17103 CHO1; CDP-diacylglycerol---serine O-phosphatidyltransferase [EC:2.7.8.8]" }, { "name":"R0135_14925 asd; (GenBank) archaetidylserine decarboxylase\tK01613 psd; phosphatidylserine decarboxylase [EC:4.1.1.65]" }, { "name":"R0135_03390 pgsA; (GenBank) CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase\tK00995 PGS1; CDP-diacylglycerol---glycerol-3-phosphate 3-phosphatidyltransferase [EC:2.7.8.5]" }, { "name":"R0135_15470 phosphatidylglycerophosphatase A\tK01095 pgpA; phosphatidylglycerophosphatase A [EC:3.1.3.27]" }, { "name":"R0135_06960 cls; (GenBank) cardiolipin synthase\tK06131 clsA_B; cardiolipin synthase A\/B [EC:2.7.8.-]" }, { "name":"R0135_04370 phospholipase D family protein\tK06132 clsC; cardiolipin synthase C [EC:2.7.8.-]" }, { "name":"R0135_13245 phospholipase D family protein\tK06132 clsC; cardiolipin synthase C [EC:2.7.8.-]" } ] }, { "name":"00565 Ether lipid metabolism [PATH:cvb00565]", "children":[ { "name":"R0135_06670 phospholipase A\tK01058 pldA; phospholipase A1\/A2 [EC:3.1.1.32 3.1.1.4]" } ] }, { "name":"00600 Sphingolipid metabolism [PATH:cvb00600]", "children":[ { "name":"R0135_00110 arylsulfatase\tK01130 atsA; arylsulfatase [EC:3.1.6.1]" }, { "name":"R0135_04280 arylsulfatase\tK01130 atsA; arylsulfatase [EC:3.1.6.1]" }, { "name":"R0135_04880 arylsulfatase\tK01130 atsA; arylsulfatase [EC:3.1.6.1]" }, { "name":"R0135_05265 sulfatase-like hydrolase\/transferase\tK01130 atsA; arylsulfatase [EC:3.1.6.1]" }, { "name":"R0135_06160 arylsulfatase\tK01130 atsA; arylsulfatase [EC:3.1.6.1]" }, { "name":"R0135_09070 arylsulfatase\tK01130 atsA; arylsulfatase [EC:3.1.6.1]" }, { "name":"R0135_13110 arylsulfatase\tK01130 atsA; arylsulfatase [EC:3.1.6.1]" }, { "name":"R0135_05115 alpha-galactosidase\tK07407 E3.2.1.22B; alpha-galactosidase [EC:3.2.1.22]" } ] }, { "name":"00590 Arachidonic acid metabolism", "children":[ { "name":"R0135_06670 phospholipase A\tK01058 pldA; phospholipase A1\/A2 [EC:3.1.1.32 3.1.1.4]" } ] }, { "name":"00591 Linoleic acid metabolism", "children":[ { "name":"R0135_06670 phospholipase A\tK01058 pldA; phospholipase A1\/A2 [EC:3.1.1.32 3.1.1.4]" } ] }, { "name":"00592 alpha-Linolenic acid metabolism [PATH:cvb00592]", "children":[ { "name":"R0135_06670 phospholipase A\tK01058 pldA; phospholipase A1\/A2 [EC:3.1.1.32 3.1.1.4]" }, { "name":"R0135_08785 acetyl-CoA C-acyltransferase\tK00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16]" }, { "name":"R0135_09400 fadA; (GenBank) acetyl-CoA C-acyltransferase FadA\tK00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16]" } ] }, { "name":"01040 Biosynthesis of unsaturated fatty acids [PATH:cvb01040]", "children":[ { "name":"R0135_09275 fatty acid desaturase\tK00507 SCD; stearoyl-CoA desaturase (Delta-9 desaturase) [EC:1.14.19.1]" }, { "name":"R0135_02095 arylesterase\tK10804 tesA; acyl-CoA thioesterase I [EC:3.1.2.- 3.1.2.2 3.1.1.2 3.1.1.5]" }, { "name":"R0135_16680 acyl-CoA thioesterase II\tK10805 tesB; acyl-CoA thioesterase II [EC:3.1.2.20]" }, { "name":"R0135_11595 acyl-CoA thioesterase\tK10806 yciA; acyl-CoA thioesterase [EC:3.1.2.-]" } ] } ] }, { "name":"09104 Nucleotide metabolism", "children":[ { "name":"00230 Purine metabolism [PATH:cvb00230]", "children":[ { "name":"R0135_16965 NUDIX domain-containing protein\tK01515 nudF; ADP-ribose diphosphatase [EC:3.6.1.13 3.6.1.-]" }, { "name":"R0135_11475 phosphomannomutase\/phosphoglucomutase\tK15778 pmm-pgm; phosphomannomutase \/ phosphoglucomutase [EC:5.4.2.8 5.4.2.2]" }, { "name":"R0135_00910 ribose-phosphate diphosphokinase\tK00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]" }, { "name":"R0135_07555 ribose-phosphate pyrophosphokinase\tK00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]" }, { "name":"R0135_03835 purF; (GenBank) amidophosphoribosyltransferase\tK00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]" }, { "name":"R0135_14555 purD; (GenBank) phosphoribosylamine--glycine ligase\tK01945 purD; phosphoribosylamine---glycine ligase [EC:6.3.4.13]" }, { "name":"R0135_17415 purN; (GenBank) phosphoribosylglycinamide formyltransferase\tK11175 purN; phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2]" }, { "name":"R0135_09965 purT; (GenBank) formate-dependent phosphoribosylglycinamide formyltransferase\tK08289 purT; phosphoribosylglycinamide formyltransferase 2 [EC:6.3.1.21]" }, { "name":"R0135_00935 purL; (GenBank) phosphoribosylformylglycinamidine synthase\tK01952 PFAS; phosphoribosylformylglycinamidine synthase [EC:6.3.5.3]" }, { "name":"R0135_17420 purM; (GenBank) phosphoribosylformylglycinamidine cyclo-ligase\tK01933 purM; phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.3.1]" }, { "name":"R0135_04470 5-(carboxyamino)imidazole ribonucleotide synthase\tK01589 purK; 5-(carboxyamino)imidazole ribonucleotide synthase [EC:6.3.4.18]" }, { "name":"R0135_04475 purE; (GenBank) 5-(carboxyamino)imidazole ribonucleotide mutase\tK01588 purE; 5-(carboxyamino)imidazole ribonucleotide mutase [EC:5.4.99.18]" }, { "name":"R0135_01900 purC; (GenBank) phosphoribosylaminoimidazolesuccinocarboxamide synthase\tK01923 purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:6.3.2.6]" }, { "name":"R0135_02605 purB; (GenBank) adenylosuccinate lyase\tK01756 purB; adenylosuccinate lyase [EC:4.3.2.2]" }, { "name":"R0135_14560 purH; (GenBank) bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase\/IMP cyclohydrolase\tK00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase \/ IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]" }, { "name":"R0135_02540 5'-nucleotidase\tK01081 E3.1.3.5; 5'-nucleotidase [EC:3.1.3.5]" }, { "name":"R0135_15540 yrfG; (GenBank) GMP\/IMP nucleotidase\tK20881 yrfG; GMP\/IMP 5'-nucleotidase [EC:3.1.3.-]" }, { "name":"R0135_17050 pgeF; (GenBank) peptidoglycan editing factor PgeF\tK05810 LACC1; purine-nucleoside\/S-methyl-5'-thioadenosine phosphorylase \/ adenosine deaminase [EC:2.4.2.1 2.4.2.28 3.5.4.4]" }, { "name":"R0135_00830 guaB; (GenBank) IMP dehydrogenase\tK00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]" }, { "name":"R0135_00965 ndk; (GenBank) nucleoside-diphosphate kinase\tK00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]" }, { "name":"R0135_11395 rdgB; (GenBank) RdgB\/HAM1 family non-canonical purine NTP pyrophosphatase\tK01519 rdgB; XTP\/dITP diphosphohydrolase [EC:3.6.1.66]" }, { "name":"R0135_02750 xdhA; (GenBank) xanthine dehydrogenase small subunit\tK13481 xdhA; xanthine dehydrogenase small subunit [EC:1.17.1.4]" }, { "name":"R0135_02745 xdhB; (GenBank) xanthine dehydrogenase molybdopterin binding subunit\tK13482 xdhB; xanthine dehydrogenase large subunit [EC:1.17.1.4]" }, { "name":"R0135_00835 guaA; (GenBank) glutamine-hydrolyzing GMP synthase\tK01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]" }, { "name":"R0135_02715 guaD; (GenBank) guanine deaminase\tK01487 guaD; guanine deaminase [EC:3.5.4.3]" }, { "name":"R0135_11515 gmk; (GenBank) guanylate kinase\tK00942 gmk; guanylate kinase [EC:2.7.4.8]" }, { "name":"R0135_09370 ribonucleoside-diphosphate reductase subunit alpha\tK00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]" }, { "name":"R0135_09375 ribonucleotide-diphosphate reductase subunit beta\tK00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]" }, { "name":"R0135_11525 RelA\/SpoT family protein\tK01139 spoT; GTP diphosphokinase \/ guanosine-3',5'-bis(diphosphate) 3'-diphosphatase [EC:2.7.6.5 3.1.7.2]" }, { "name":"R0135_01475 Ppx\/GppA phosphatase family protein\tK01524 ppx-gppA; exopolyphosphatase \/ guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase [EC:3.6.1.11 3.6.1.40]" }, { "name":"R0135_01840 relA; (GenBank) GTP diphosphokinase\tK00951 relA; GTP pyrophosphokinase [EC:2.7.6.5]" }, { "name":"R0135_00815 adenylate\/guanylate cyclase domain-containing protein\tK01768 E4.6.1.1; adenylate cyclase [EC:4.6.1.1]" }, { "name":"R0135_06550 tetratricopeptide repeat protein\tK01768 E4.6.1.1; adenylate cyclase [EC:4.6.1.1]" }, { "name":"R0135_15000 adenylosuccinate synthase\tK01939 purA; adenylosuccinate synthase [EC:6.3.4.4]" }, { "name":"R0135_00410 adenosine deaminase\tK01488 add; adenosine deaminase [EC:3.5.4.4]" }, { "name":"R0135_08535 ppnN; (GenBank) nucleotide 5'-monophosphate nucleosidase PpnN\tK06966 ppnN; pyrimidine\/purine-5'-nucleotide nucleosidase [EC:3.2.2.10 3.2.2.-]" }, { "name":"R0135_13370 adenine deaminase C-terminal domain-containing protein\tK01486 ade; adenine deaminase [EC:3.5.4.2]" }, { "name":"R0135_00355 add; (GenBank) adenosine deaminase\tK21053 ade; adenine deaminase [EC:3.5.4.2]" }, { "name":"R0135_00425 adenosine deaminase\tK21053 ade; adenine deaminase [EC:3.5.4.2]" }, { "name":"R0135_01850 adk; (GenBank) adenylate kinase\tK00939 adk; adenylate kinase [EC:2.7.4.3]" }, { "name":"R0135_01845 mazG; (GenBank) nucleoside triphosphate pyrophosphohydrolase\tK04765 mazG; nucleoside triphosphate diphosphatase [EC:3.6.1.9]" }, { "name":"R0135_12165 cpdA; (GenBank) 3',5'-cyclic-AMP phosphodiesterase\tK03651 cpdA; 3',5'-cyclic-AMP phosphodiesterase [EC:3.1.4.53]" }, { "name":"R0135_14370 symmetrical bis(5'-nucleosyl)-tetraphosphatase\tK01525 apaH; bis(5'-nucleosyl)-tetraphosphatase (symmetrical) [EC:3.6.1.41]" }, { "name":"R0135_07050 cysC; (GenBank) adenylyl-sulfate kinase\tK00860 cysC; adenylylsulfate kinase [EC:2.7.1.25]" }, { "name":"R0135_07045 sat; (GenBank) sulfate adenylyltransferase\tK00958 sat; sulfate adenylyltransferase [EC:2.7.7.4]" }, { "name":"R0135_02725 uraH; (GenBank) hydroxyisourate hydrolase\tK07127 uraH; 5-hydroxyisourate hydrolase [EC:3.5.2.17]" }, { "name":"R0135_02730 uraD; (GenBank) 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase\tK16840 hpxQ; 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [EC:4.1.1.97]" }, { "name":"R0135_00405 puuE; (GenBank) allantoinase PuuE\tK16842 hpxB; allantoinase [EC:3.5.2.5]" }, { "name":"R0135_02735 alc; (GenBank) allantoicase\tK01477 alc; allantoicase [EC:3.5.3.4]" }, { "name":"R0135_02720 ureidoglycolate lyase\tK01483 allA; ureidoglycolate lyase [EC:4.3.2.3]" }, { "name":"R0135_02770 ureC; (GenBank) urease subunit alpha\tK01428 ureC; urease subunit alpha [EC:3.5.1.5]" }, { "name":"R0135_02775 urease subunit beta\tK01429 ureB; urease subunit beta [EC:3.5.1.5]" }, { "name":"R0135_02780 ureA; (GenBank) urease subunit gamma\tK01430 ureA; urease subunit gamma [EC:3.5.1.5]" } ] }, { "name":"00240 Pyrimidine metabolism [PATH:cvb00240]", "children":[ { "name":"R0135_04545 ATP-grasp domain-containing protein\tK01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]" }, { "name":"R0135_08750 carB; (GenBank) carbamoyl-phosphate synthase large subunit\tK01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]" }, { "name":"R0135_08755 carA; (GenBank) glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit\tK01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5]" }, { "name":"R0135_16960 aspartate carbamoyltransferase\tK00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2]" }, { "name":"R0135_06285 D-aminoacylase\tK01465 URA4; dihydroorotase [EC:3.5.2.3]" }, { "name":"R0135_08565 pyrC; (GenBank) dihydroorotase\tK01465 URA4; dihydroorotase [EC:3.5.2.3]" }, { "name":"R0135_10320 tRNA-dihydrouridine synthase\tK17828 pyrDI; dihydroorotate dehydrogenase (NAD+) catalytic subunit [EC:1.3.1.14]" }, { "name":"R0135_06255 dihydroorotate dehydrogenase-like protein\tK00226 pyrD; dihydroorotate dehydrogenase (fumarate) [EC:1.3.98.1]" }, { "name":"R0135_11495 pyrE; (GenBank) orotate phosphoribosyltransferase\tK00762 pyrE; orotate phosphoribosyltransferase [EC:2.4.2.10]" }, { "name":"R0135_06765 pyrF; (GenBank) orotidine-5'-phosphate decarboxylase\tK01591 pyrF; orotidine-5'-phosphate decarboxylase [EC:4.1.1.23]" }, { "name":"R0135_00035 pyrH; (GenBank) UMP kinase\tK09903 pyrH; uridylate kinase [EC:2.7.4.22]" }, { "name":"R0135_00965 ndk; (GenBank) nucleoside-diphosphate kinase\tK00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]" }, { "name":"R0135_01845 mazG; (GenBank) nucleoside triphosphate pyrophosphohydrolase\tK04765 mazG; nucleoside triphosphate diphosphatase [EC:3.6.1.9]" }, { "name":"R0135_07445 Maf family protein\tK06287 yhdE; nucleoside triphosphate pyrophosphatase [EC:3.6.1.-]" }, { "name":"R0135_05400 CTP synthase\tK01937 pyrG; CTP synthase [EC:6.3.4.2]" }, { "name":"R0135_06790 cmk; (GenBank) (d)CMP kinase\tK00945 cmk; CMP\/dCMP kinase [EC:2.7.4.25]" }, { "name":"R0135_01890 udk; (GenBank) uridine kinase\tK00876 udk; uridine kinase [EC:2.7.1.48]" }, { "name":"R0135_02540 5'-nucleotidase\tK01081 E3.1.3.5; 5'-nucleotidase [EC:3.1.3.5]" }, { "name":"R0135_08535 ppnN; (GenBank) nucleotide 5'-monophosphate nucleosidase PpnN\tK06966 ppnN; pyrimidine\/purine-5'-nucleotide nucleosidase [EC:3.2.2.10 3.2.2.-]" }, { "name":"R0135_17405 dcd; (GenBank) dCTP deaminase\tK01494 dcd; dCTP deaminase [EC:3.5.4.13]" }, { "name":"R0135_09370 ribonucleoside-diphosphate reductase subunit alpha\tK00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]" }, { "name":"R0135_09375 ribonucleotide-diphosphate reductase subunit beta\tK00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]" }, { "name":"R0135_03085 tmk; (GenBank) dTMP kinase\tK00943 tmk; dTMP kinase [EC:2.7.4.9]" }, { "name":"R0135_00905 thymidine phosphorylase family protein\tK00758 deoA; thymidine phosphorylase [EC:2.4.2.4]" }, { "name":"R0135_14735 thymidine kinase\tK00857 tdk; thymidine kinase [EC:2.7.1.21]" }, { "name":"R0135_11150 thymidylate synthase\tK00560 thyA; thymidylate synthase [EC:2.1.1.45]" }, { "name":"R0135_06435 Zn-dependent hydrolase\tK06016 pydC; beta-ureidopropionase \/ N-carbamoyl-L-amino-acid hydrolase [EC:3.5.1.6 3.5.1.87]" }, { "name":"R0135_13385 Zn-dependent hydrolase\tK06016 pydC; beta-ureidopropionase \/ N-carbamoyl-L-amino-acid hydrolase [EC:3.5.1.6 3.5.1.87]" } ] } ] }, { "name":"09105 Amino acid metabolism", "children":[ { "name":"00250 Alanine, aspartate and glutamate metabolism [PATH:cvb00250]", "children":[ { "name":"R0135_08335 amino acid aminotransferase\tK00813 aspC; aspartate aminotransferase [EC:2.6.1.1]" }, { "name":"R0135_01770 nadB; (GenBank) L-aspartate oxidase\tK00278 nadB; L-aspartate oxidase [EC:1.4.3.16]" }, { "name":"R0135_04080 amino acid racemase\tK01779 racD; aspartate racemase [EC:5.1.1.13]" }, { "name":"R0135_03965 asparaginase domain-containing protein\tK01424 E3.5.1.1; L-asparaginase [EC:3.5.1.1]" }, { "name":"R0135_12670 asparaginase\tK01424 E3.5.1.1; L-asparaginase [EC:3.5.1.1]" }, { "name":"R0135_03775 asparagine synthase-related protein\tK01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]" }, { "name":"R0135_07715 asnB; (GenBank) asparagine synthase (glutamine-hydrolyzing)\tK01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]" }, { "name":"R0135_05010 amidohydrolase\tK13566 NIT2; omega-amidase [EC:3.5.1.3]" }, { "name":"R0135_03940 alanine--glyoxylate aminotransferase family protein\tK00830 AGXT; alanine-glyoxylate transaminase \/ serine-glyoxylate transaminase \/ serine-pyruvate transaminase [EC:2.6.1.44 2.6.1.45 2.6.1.51]" }, { "name":"R0135_07130 ald; (GenBank) alanine dehydrogenase\tK00259 ald; alanine dehydrogenase [EC:1.4.1.1]" }, { "name":"R0135_08560 argininosuccinate synthase\tK01940 argG; argininosuccinate synthase [EC:6.3.4.5]" }, { "name":"R0135_09665 argH; (GenBank) argininosuccinate lyase\tK01755 argH; argininosuccinate lyase [EC:4.3.2.1]" }, { "name":"R0135_15000 adenylosuccinate synthase\tK01939 purA; adenylosuccinate synthase [EC:6.3.4.4]" }, { "name":"R0135_02605 purB; (GenBank) adenylosuccinate lyase\tK01756 purB; adenylosuccinate lyase [EC:4.3.2.2]" }, { "name":"R0135_16960 aspartate carbamoyltransferase\tK00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2]" }, { "name":"R0135_10365 aminotransferase\tK16871 POP2; 4-aminobutyrate---pyruvate transaminase [EC:2.6.1.96]" }, { "name":"R0135_01960 NAD-dependent succinate-semialdehyde dehydrogenase\tK00135 gabD; succinate-semialdehyde dehydrogenase \/ glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]" }, { "name":"R0135_12730 gltB; (GenBank) glutamate synthase large subunit\tK00265 gltB; glutamate synthase (NADPH) large chain [EC:1.4.1.13]" }, { "name":"R0135_12735 FAD-dependent oxidoreductase\tK00266 gltD; glutamate synthase (NADPH) small chain [EC:1.4.1.13]" }, { "name":"R0135_04195 NAD-glutamate dehydrogenase\tK15371 GDH2; glutamate dehydrogenase [EC:1.4.1.2]" }, { "name":"R0135_13650 putA; (GenBank) bifunctional proline dehydrogenase\/L-glutamate gamma-semialdehyde dehydrogenase PutA\tK13821 putA; RHH-type transcriptional regulator, proline utilization regulon repressor \/ proline dehydrogenase \/ delta 1-pyrroline-5-carboxylate dehydrogenase [EC:1.5.5.2 1.2.1.88]" }, { "name":"R0135_08950 glutamine synthetase family protein\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]" }, { "name":"R0135_09260 glutamine synthetase family protein\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]" }, { "name":"R0135_10760 glutamine synthetase family protein\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]" }, { "name":"R0135_12435 glnA; (GenBank) glutamate--ammonia ligase\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]" }, { "name":"R0135_12885 glutamine synthetase family protein\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]" }, { "name":"R0135_04545 ATP-grasp domain-containing protein\tK01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]" }, { "name":"R0135_08750 carB; (GenBank) carbamoyl-phosphate synthase large subunit\tK01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]" }, { "name":"R0135_08755 carA; (GenBank) glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit\tK01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5]" }, { "name":"R0135_11635 glmS; (GenBank) glutamine--fructose-6-phosphate transaminase (isomerizing)\tK00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]" }, { "name":"R0135_03835 purF; (GenBank) amidophosphoribosyltransferase\tK00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]" } ] }, { "name":"00260 Glycine, serine and threonine metabolism [PATH:cvb00260]", "children":[ { "name":"R0135_00205 aspartate kinase\tK00928 lysC; aspartate kinase [EC:2.7.2.4]" }, { "name":"R0135_03885 aspartate-semialdehyde dehydrogenase\tK00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]" }, { "name":"R0135_00775 homoserine dehydrogenase\tK00003 hom; homoserine dehydrogenase [EC:1.1.1.3]" }, { "name":"R0135_00780 thrC; (GenBank) threonine synthase\tK01733 thrC; threonine synthase [EC:4.2.3.1]" }, { "name":"R0135_06685 ltaE; (GenBank) low-specificity L-threonine aldolase\tK01620 ltaE; threonine aldolase [EC:4.1.2.48]" }, { "name":"R0135_15430 glyA; (GenBank) serine hydroxymethyltransferase\tK00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]" }, { "name":"R0135_03940 alanine--glyoxylate aminotransferase family protein\tK00830 AGXT; alanine-glyoxylate transaminase \/ serine-glyoxylate transaminase \/ serine-pyruvate transaminase [EC:2.6.1.44 2.6.1.45 2.6.1.51]" }, { "name":"R0135_12395 gpmI; (GenBank) 2,3-bisphosphoglycerate-independent phosphoglycerate mutase\tK15633 gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12]" }, { "name":"R0135_16760 hypothetical protein\tK15918 GLYK; D-glycerate 3-kinase [EC:2.7.1.31]" }, { "name":"R0135_11245 serA; (GenBank) phosphoglycerate dehydrogenase\tK00058 serA; D-3-phosphoglycerate dehydrogenase \/ 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]" }, { "name":"R0135_13440 phosphoglycerate dehydrogenase\tK00058 serA; D-3-phosphoglycerate dehydrogenase \/ 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]" }, { "name":"R0135_06810 serC; (GenBank) 3-phosphoserine\/phosphohydroxythreonine transaminase\tK00831 serC; phosphoserine aminotransferase [EC:2.6.1.52]" }, { "name":"R0135_12485 serB; (GenBank) phosphoserine phosphatase SerB\tK01079 serB; phosphoserine phosphatase [EC:3.1.3.3]" }, { "name":"R0135_05610 glycine C-acetyltransferase\tK00639 kbl; glycine C-acetyltransferase [EC:2.3.1.29]" }, { "name":"R0135_05605 tdh; (GenBank) L-threonine 3-dehydrogenase\tK00060 tdh; threonine 3-dehydrogenase [EC:1.1.1.103]" }, { "name":"R0135_15090 FAD-dependent oxidoreductase\tK00274 MAO; monoamine oxidase [EC:1.4.3.4]" }, { "name":"R0135_00165 gcvP; (GenBank) aminomethyl-transferring glycine dehydrogenase\tK00281 GLDC; glycine cleavage system P protein (glycine dehydrogenase) [EC:1.4.4.2]" }, { "name":"R0135_12905 gcvT; (GenBank) glycine cleavage system aminomethyltransferase GcvT\tK00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]" }, { "name":"R0135_02270 lpdA; (GenBank) dihydrolipoyl dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]" }, { "name":"R0135_11180 gcvH; (GenBank) glycine cleavage system protein GcvH\tK02437 gcvH; glycine cleavage system H protein" }, { "name":"R0135_17085 pssA; (GenBank) CDP-diacylglycerol--serine O-phosphatidyltransferase\tK17103 CHO1; CDP-diacylglycerol---serine O-phosphatidyltransferase [EC:2.7.8.8]" }, { "name":"R0135_04995 betA; (GenBank) choline dehydrogenase\tK00108 betA; choline dehydrogenase [EC:1.1.99.1]" }, { "name":"R0135_04990 betB; (GenBank) betaine-aldehyde dehydrogenase\tK00130 betB; betaine-aldehyde dehydrogenase [EC:1.2.1.8]" }, { "name":"R0135_05120 L-serine ammonia-lyase\tK01752 E4.3.1.17; L-serine dehydratase [EC:4.3.1.17]" }, { "name":"R0135_05125 threonine\/serine dehydratase\tK01754 E4.3.1.19; threonine dehydratase [EC:4.3.1.19]" }, { "name":"R0135_05545 threonine dehydratase\tK01754 E4.3.1.19; threonine dehydratase [EC:4.3.1.19]" }, { "name":"R0135_11230 ilvA; (GenBank) threonine ammonia-lyase, biosynthetic\tK01754 E4.3.1.19; threonine dehydratase [EC:4.3.1.19]" }, { "name":"R0135_03860 trpA; (GenBank) tryptophan synthase subunit alpha\tK01695 trpA; tryptophan synthase alpha chain [EC:4.2.1.20]" }, { "name":"R0135_03865 trpB; (GenBank) tryptophan synthase subunit beta\tK01696 trpB; tryptophan synthase beta chain [EC:4.2.1.20]" }, { "name":"R0135_06565 M14 family metallopeptidase\tK15784 doeB; N2-acetyl-L-2,4-diaminobutanoate deacetylase [EC:3.5.1.125]" } ] }, { "name":"00270 Cysteine and methionine metabolism [PATH:cvb00270]", "children":[ { "name":"R0135_12745 cysE; (GenBank) serine O-acetyltransferase\tK00640 cysE; serine O-acetyltransferase [EC:2.3.1.30]" }, { "name":"R0135_13230 cysK; (GenBank) cysteine synthase A\tK01738 cysK; cysteine synthase [EC:2.5.1.47]" }, { "name":"R0135_05585 metC; (GenBank) cystathionine beta-lyase\tK01760 metC; cysteine-S-conjugate beta-lyase [EC:4.4.1.13]" }, { "name":"R0135_02980 metH; (GenBank) methionine synthase\tK00548 metH; 5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]" }, { "name":"R0135_11315 metK; (GenBank) methionine adenosyltransferase\tK00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6]" }, { "name":"R0135_10970 methyltransferase domain-containing protein\tK00797 speE; spermidine synthase [EC:2.5.1.16]" }, { "name":"R0135_17050 pgeF; (GenBank) peptidoglycan editing factor PgeF\tK05810 LACC1; purine-nucleoside\/S-methyl-5'-thioadenosine phosphorylase \/ adenosine deaminase [EC:2.4.2.1 2.4.2.28 3.5.4.4]" }, { "name":"R0135_06820 TRZ\/ATZ family hydrolase\tK12960 mtaD; 5-methylthioadenosine\/S-adenosylhomocysteine deaminase [EC:3.5.4.31 3.5.4.28]" }, { "name":"R0135_13180 amidohydrolase\tK12960 mtaD; 5-methylthioadenosine\/S-adenosylhomocysteine deaminase [EC:3.5.4.31 3.5.4.28]" }, { "name":"R0135_03505 S-methyl-5'-thioinosine phosphorylase\tK19696 mtiP; 5'-methylthioinosine phosphorylase [EC:2.4.2.44]" }, { "name":"R0135_14900 GAF domain-containing protein\tK08968 msrC; L-methionine (R)-S-oxide reductase [EC:1.8.4.14]" }, { "name":"R0135_14175 DNA cytosine methyltransferase\tK00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]" }, { "name":"R0135_11320 ahcY; (GenBank) adenosylhomocysteinase\tK01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1]" }, { "name":"R0135_00205 aspartate kinase\tK00928 lysC; aspartate kinase [EC:2.7.2.4]" }, { "name":"R0135_03885 aspartate-semialdehyde dehydrogenase\tK00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]" }, { "name":"R0135_00775 homoserine dehydrogenase\tK00003 hom; homoserine dehydrogenase [EC:1.1.1.3]" }, { "name":"R0135_01375 alpha\/beta fold hydrolase\tK00641 metX; homoserine O-acetyltransferase\/O-succinyltransferase [EC:2.3.1.31 2.3.1.46]" }, { "name":"R0135_11380 homoserine O-acetyltransferase\tK00641 metX; homoserine O-acetyltransferase\/O-succinyltransferase [EC:2.3.1.31 2.3.1.46]" }, { "name":"R0135_07890 aminotransferase class I\/II-fold pyridoxal phosphate-dependent enzyme\tK01740 metY; O-acetylhomoserine (thiol)-lyase [EC:2.5.1.49]" }, { "name":"R0135_03830 O-succinylhomoserine sulfhydrylase\tK10764 metZ; O-succinylhomoserine sulfhydrylase [EC:2.5.1.-]" }, { "name":"R0135_08350 aminotransferase class IV\tK00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]" }, { "name":"R0135_12090 branched-chain amino acid transaminase\tK00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]" }, { "name":"R0135_09580 gshA; (GenBank) glutamate--cysteine ligase\tK01919 gshA; glutamate---cysteine ligase [EC:6.3.2.2]" }, { "name":"R0135_08335 amino acid aminotransferase\tK00813 aspC; aspartate aminotransferase [EC:2.6.1.1]" }, { "name":"R0135_06890 sulfurtransferase\tK01011 TST; thiosulfate\/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2]" }, { "name":"R0135_02115 malate dehydrogenase\tK00024 mdh; malate dehydrogenase [EC:1.1.1.37]" }, { "name":"R0135_04075 D-cysteine desulfhydrase\tK17950 cuyA; L-cysteate sulfo-lyase [EC:4.4.1.25]" }, { "name":"R0135_05120 L-serine ammonia-lyase\tK01752 E4.3.1.17; L-serine dehydratase [EC:4.3.1.17]" }, { "name":"R0135_01835 cysM; (GenBank) cysteine synthase CysM\tK12339 cysM; S-sulfo-L-cysteine synthase (O-acetyl-L-serine-dependent) [EC:2.5.1.144]" }, { "name":"R0135_11245 serA; (GenBank) phosphoglycerate dehydrogenase\tK00058 serA; D-3-phosphoglycerate dehydrogenase \/ 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]" }, { "name":"R0135_13440 phosphoglycerate dehydrogenase\tK00058 serA; D-3-phosphoglycerate dehydrogenase \/ 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]" }, { "name":"R0135_06810 serC; (GenBank) 3-phosphoserine\/phosphohydroxythreonine transaminase\tK00831 serC; phosphoserine aminotransferase [EC:2.6.1.52]" } ] }, { "name":"00280 Valine, leucine and isoleucine degradation [PATH:cvb00280]", "children":[ { "name":"R0135_08350 aminotransferase class IV\tK00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]" }, { "name":"R0135_12090 branched-chain amino acid transaminase\tK00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]" }, { "name":"R0135_17450 Glu\/Leu\/Phe\/Val dehydrogenase dimerization domain-containing protein\tK00263 E1.4.1.9; leucine dehydrogenase [EC:1.4.1.9]" }, { "name":"R0135_02270 lpdA; (GenBank) dihydrolipoyl dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]" }, { "name":"R0135_05070 acyl-CoA dehydrogenase family protein\tK00249 ACADM; acyl-CoA dehydrogenase [EC:1.3.8.7]" }, { "name":"R0135_08090 acyl-CoA dehydrogenase family protein\tK00249 ACADM; acyl-CoA dehydrogenase [EC:1.3.8.7]" }, { "name":"R0135_08800 acyl-CoA dehydrogenase family protein\tK00249 ACADM; acyl-CoA dehydrogenase [EC:1.3.8.7]" }, { "name":"R0135_16005 acyl-CoA dehydrogenase family protein\tK00249 ACADM; acyl-CoA dehydrogenase [EC:1.3.8.7]" }, { "name":"R0135_15590 isovaleryl-CoA dehydrogenase\tK00253 IVD; isovaleryl-CoA dehydrogenase [EC:1.3.8.4]" }, { "name":"R0135_09395 fadB; (GenBank) fatty acid oxidation complex subunit alpha FadB\tK01825 fadB; 3-hydroxyacyl-CoA dehydrogenase \/ enoyl-CoA hydratase \/ 3-hydroxybutyryl-CoA epimerase \/ enoyl-CoA isomerase [EC:1.1.1.35 4.2.1.17 5.1.2.3 5.3.3.8]" }, { "name":"R0135_00335 3-hydroxyacyl-CoA dehydrogenase NAD-binding domain-containing protein\tK01782 fadJ; 3-hydroxyacyl-CoA dehydrogenase \/ enoyl-CoA hydratase \/ 3-hydroxybutyryl-CoA epimerase [EC:1.1.1.35 4.2.1.17 5.1.2.3]" }, { "name":"R0135_08785 acetyl-CoA C-acyltransferase\tK00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16]" }, { "name":"R0135_09400 fadA; (GenBank) acetyl-CoA C-acyltransferase FadA\tK00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16]" }, { "name":"R0135_02565 mce; (GenBank) methylmalonyl-CoA epimerase\tK05606 MCEE; methylmalonyl-CoA\/ethylmalonyl-CoA epimerase [EC:5.1.99.1]" }, { "name":"R0135_02570 scpA; (GenBank) methylmalonyl-CoA mutase\tK01847 MUT; methylmalonyl-CoA mutase [EC:5.4.99.2]" }, { "name":"R0135_16425 cobalamin-dependent protein\tK01849 E5.4.99.2B; methylmalonyl-CoA mutase, C-terminal domain [EC:5.4.99.2]" }, { "name":"R0135_16420 acyl-CoA mutase large subunit family protein\tK01848 E5.4.99.2A; methylmalonyl-CoA mutase, N-terminal domain [EC:5.4.99.2]" }, { "name":"R0135_10935 mmsB; (GenBank) 3-hydroxyisobutyrate dehydrogenase\tK00020 HIBADH; 3-hydroxyisobutyrate dehydrogenase [EC:1.1.1.31]" }, { "name":"R0135_10955 CoA-acylating methylmalonate-semialdehyde dehydrogenase\tK00140 mmsA; malonate-semialdehyde dehydrogenase (acetylating) \/ methylmalonate-semialdehyde dehydrogenase [EC:1.2.1.18 1.2.1.27]" }, { "name":"R0135_01945 aldehyde dehydrogenase family protein\tK00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]" }, { "name":"R0135_04855 acyl-CoA synthetase\tK18660 ACSF3; malonyl-CoA\/methylmalonyl-CoA synthetase [EC:6.2.1.76 6.2.1.-]" }, { "name":"R0135_08990 aspartate aminotransferase family protein\tK00822 E2.6.1.18; beta-alanine--pyruvate transaminase [EC:2.6.1.18]" }, { "name":"R0135_15575 acetyl\/propionyl\/methylcrotonyl-CoA carboxylase subunit alpha\tK01968 MCCC1; 3-methylcrotonyl-CoA carboxylase alpha subunit [EC:6.4.1.4]" }, { "name":"R0135_15585 carboxyl transferase domain-containing protein\tK01969 MCCC2; 3-methylcrotonyl-CoA carboxylase beta subunit [EC:6.4.1.4]" }, { "name":"R0135_15580 enoyl-CoA hydratase\/isomerase family protein\tK13766 liuC; methylglutaconyl-CoA hydratase [EC:4.2.1.18]" }, { "name":"R0135_00130 hydroxymethylglutaryl-CoA lyase\tK01640 HMGCL; hydroxymethylglutaryl-CoA lyase [EC:4.1.3.4]" }, { "name":"R0135_15570 hydroxymethylglutaryl-CoA lyase\tK01640 HMGCL; hydroxymethylglutaryl-CoA lyase [EC:4.1.3.4]" }, { "name":"R0135_08320 CoA transferase subunit A\tK01028 scoA; 3-oxoacid CoA-transferase subunit A [EC:2.8.3.5]" }, { "name":"R0135_08315 3-oxoacid CoA-transferase subunit B\tK01029 scoB; 3-oxoacid CoA-transferase subunit B [EC:2.8.3.5]" }, { "name":"R0135_00330 acetyl-CoA C-acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" }, { "name":"R0135_03970 acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" }, { "name":"R0135_04435 acetyl-CoA C-acyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" }, { "name":"R0135_05075 acetyl-CoA C-acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" }, { "name":"R0135_11080 acetyl-CoA C-acyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" }, { "name":"R0135_11085 acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" } ] }, { "name":"00290 Valine, leucine and isoleucine biosynthesis [PATH:cvb00290]", "children":[ { "name":"R0135_05125 threonine\/serine dehydratase\tK01754 E4.3.1.19; threonine dehydratase [EC:4.3.1.19]" }, { "name":"R0135_05545 threonine dehydratase\tK01754 E4.3.1.19; threonine dehydratase [EC:4.3.1.19]" }, { "name":"R0135_11230 ilvA; (GenBank) threonine ammonia-lyase, biosynthetic\tK01754 E4.3.1.19; threonine dehydratase [EC:4.3.1.19]" }, { "name":"R0135_03900 leuC; (GenBank) 3-isopropylmalate dehydratase large subunit\tK01703 leuC; 3-isopropylmalate\/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35]" }, { "name":"R0135_03895 leuD; (GenBank) 3-isopropylmalate dehydratase small subunit\tK01704 leuD; 3-isopropylmalate\/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35]" }, { "name":"R0135_03890 leuB; (GenBank) 3-isopropylmalate dehydrogenase\tK00052 leuB; 3-isopropylmalate dehydrogenase [EC:1.1.1.85]" }, { "name":"R0135_01660 5-guanidino-2-oxopentanoate decarboxylase\tK01652 E2.2.1.6L; acetolactate synthase I\/II\/III large subunit [EC:2.2.1.6]" }, { "name":"R0135_04490 acetolactate synthase large subunit\tK01652 E2.2.1.6L; acetolactate synthase I\/II\/III large subunit [EC:2.2.1.6]" }, { "name":"R0135_04820 ilvB; (GenBank) biosynthetic-type acetolactate synthase large subunit\tK01652 E2.2.1.6L; acetolactate synthase I\/II\/III large subunit [EC:2.2.1.6]" }, { "name":"R0135_05855 acetolactate synthase large subunit\tK01652 E2.2.1.6L; acetolactate synthase I\/II\/III large subunit [EC:2.2.1.6]" }, { "name":"R0135_17065 acetolactate synthase 3 large subunit\tK01652 E2.2.1.6L; acetolactate synthase I\/II\/III large subunit [EC:2.2.1.6]" }, { "name":"R0135_17070 ilvN; (GenBank) acetolactate synthase small subunit\tK01653 E2.2.1.6S; acetolactate synthase I\/III small subunit [EC:2.2.1.6]" }, { "name":"R0135_17075 ilvC; (GenBank) ketol-acid reductoisomerase\tK00053 ilvC; ketol-acid reductoisomerase [EC:1.1.1.86]" }, { "name":"R0135_04485 ilvD; (GenBank) dihydroxy-acid dehydratase\tK01687 ilvD; dihydroxy-acid dehydratase [EC:4.2.1.9]" }, { "name":"R0135_05925 ilvD; (GenBank) dihydroxy-acid dehydratase\tK01687 ilvD; dihydroxy-acid dehydratase [EC:4.2.1.9]" }, { "name":"R0135_08220 dihydroxy-acid dehydratase\tK01687 ilvD; dihydroxy-acid dehydratase [EC:4.2.1.9]" }, { "name":"R0135_08350 aminotransferase class IV\tK00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]" }, { "name":"R0135_12090 branched-chain amino acid transaminase\tK00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]" }, { "name":"R0135_17450 Glu\/Leu\/Phe\/Val dehydrogenase dimerization domain-containing protein\tK00263 E1.4.1.9; leucine dehydrogenase [EC:1.4.1.9]" }, { "name":"R0135_04025 valine--pyruvate transaminase\tK00835 avtA; valine--pyruvate aminotransferase [EC:2.6.1.66]" }, { "name":"R0135_12045 leuA; (GenBank) 2-isopropylmalate synthase\tK01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13]" } ] }, { "name":"00300 Lysine biosynthesis [PATH:cvb00300]", "children":[ { "name":"R0135_00775 homoserine dehydrogenase\tK00003 hom; homoserine dehydrogenase [EC:1.1.1.3]" }, { "name":"R0135_00205 aspartate kinase\tK00928 lysC; aspartate kinase [EC:2.7.2.4]" }, { "name":"R0135_03885 aspartate-semialdehyde dehydrogenase\tK00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]" }, { "name":"R0135_17530 dapA; (GenBank) 4-hydroxy-tetrahydrodipicolinate synthase\tK01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7]" }, { "name":"R0135_16640 dapB; (GenBank) 4-hydroxy-tetrahydrodipicolinate reductase\tK00215 dapB; 4-hydroxy-tetrahydrodipicolinate reductase [EC:1.17.1.8]" }, { "name":"R0135_17565 dapD; (GenBank) 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase\tK00674 dapD; 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase [EC:2.3.1.117]" }, { "name":"R0135_09360 aspartate aminotransferase family protein\tK00821 argD; acetylornithine\/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17]" }, { "name":"R0135_00010 dapC; (GenBank) succinyldiaminopimelate transaminase\tK14267 dapC; N-succinyldiaminopimelate aminotransferase [EC:2.6.1.17]" }, { "name":"R0135_17560 dapE; (GenBank) succinyl-diaminopimelate desuccinylase\tK01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18]" }, { "name":"R0135_09680 dapF; (GenBank) diaminopimelate epimerase\tK01778 dapF; diaminopimelate epimerase [EC:5.1.1.7]" }, { "name":"R0135_04540 alanine racemase\tK01586 lysA; diaminopimelate decarboxylase [EC:4.1.1.20]" }, { "name":"R0135_09675 lysA; (GenBank) diaminopimelate decarboxylase\tK01586 lysA; diaminopimelate decarboxylase [EC:4.1.1.20]" }, { "name":"R0135_07240 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase\tK01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13]" }, { "name":"R0135_07235 murF; (GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase\tK01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10]" } ] }, { "name":"00310 Lysine degradation [PATH:cvb00310]", "children":[ { "name":"R0135_02265 odhB; (GenBank) 2-oxoglutarate dehydrogenase complex dihydrolipoyllysine-residue succinyltransferase\tK00658 DLST; 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61]" }, { "name":"R0135_02270 lpdA; (GenBank) dihydrolipoyl dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]" }, { "name":"R0135_10745 acyl-CoA dehydrogenase\tK00252 GCDH; glutaryl-CoA dehydrogenase [EC:1.3.8.6]" }, { "name":"R0135_09395 fadB; (GenBank) fatty acid oxidation complex subunit alpha FadB\tK01825 fadB; 3-hydroxyacyl-CoA dehydrogenase \/ enoyl-CoA hydratase \/ 3-hydroxybutyryl-CoA epimerase \/ enoyl-CoA isomerase [EC:1.1.1.35 4.2.1.17 5.1.2.3 5.3.3.8]" }, { "name":"R0135_00335 3-hydroxyacyl-CoA dehydrogenase NAD-binding domain-containing protein\tK01782 fadJ; 3-hydroxyacyl-CoA dehydrogenase \/ enoyl-CoA hydratase \/ 3-hydroxybutyryl-CoA epimerase [EC:1.1.1.35 4.2.1.17 5.1.2.3]" }, { "name":"R0135_00330 acetyl-CoA C-acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" }, { "name":"R0135_03970 acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" }, { "name":"R0135_04435 acetyl-CoA C-acyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" }, { "name":"R0135_05075 acetyl-CoA C-acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" }, { "name":"R0135_11080 acetyl-CoA C-acyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" }, { "name":"R0135_11085 acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" }, { "name":"R0135_01960 NAD-dependent succinate-semialdehyde dehydrogenase\tK00135 gabD; succinate-semialdehyde dehydrogenase \/ glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]" }, { "name":"R0135_00125 CoA transferase\tK01041 gcdG; glutaryl-CoA transferase [EC:2.8.3.-]" }, { "name":"R0135_10740 CoA transferase\tK01041 gcdG; glutaryl-CoA transferase [EC:2.8.3.-]" }, { "name":"R0135_01490 aminotransferase class IV\tK00824 dat; D-alanine transaminase [EC:2.6.1.21]" }, { "name":"R0135_01945 aldehyde dehydrogenase family protein\tK00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]" } ] }, { "name":"00220 Arginine biosynthesis [PATH:cvb00220]", "children":[ { "name":"R0135_09365 argF; (GenBank) ornithine carbamoyltransferase\tK00611 OTC; ornithine carbamoyltransferase [EC:2.1.3.3]" }, { "name":"R0135_08560 argininosuccinate synthase\tK01940 argG; argininosuccinate synthase [EC:6.3.4.5]" }, { "name":"R0135_09665 argH; (GenBank) argininosuccinate lyase\tK01755 argH; argininosuccinate lyase [EC:4.3.2.1]" }, { "name":"R0135_02770 ureC; (GenBank) urease subunit alpha\tK01428 ureC; urease subunit alpha [EC:3.5.1.5]" }, { "name":"R0135_02775 urease subunit beta\tK01429 ureB; urease subunit beta [EC:3.5.1.5]" }, { "name":"R0135_02780 ureA; (GenBank) urease subunit gamma\tK01430 ureA; urease subunit gamma [EC:3.5.1.5]" }, { "name":"R0135_08950 glutamine synthetase family protein\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]" }, { "name":"R0135_09260 glutamine synthetase family protein\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]" }, { "name":"R0135_10760 glutamine synthetase family protein\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]" }, { "name":"R0135_12435 glnA; (GenBank) glutamate--ammonia ligase\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]" }, { "name":"R0135_12885 glutamine synthetase family protein\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]" }, { "name":"R0135_04545 ATP-grasp domain-containing protein\tK01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]" }, { "name":"R0135_08750 carB; (GenBank) carbamoyl-phosphate synthase large subunit\tK01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]" }, { "name":"R0135_08755 carA; (GenBank) glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit\tK01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5]" }, { "name":"R0135_04195 NAD-glutamate dehydrogenase\tK15371 GDH2; glutamate dehydrogenase [EC:1.4.1.2]" }, { "name":"R0135_08335 amino acid aminotransferase\tK00813 aspC; aspartate aminotransferase [EC:2.6.1.1]" }, { "name":"R0135_12065 argA; (GenBank) amino-acid N-acetyltransferase\tK14682 argAB; amino-acid N-acetyltransferase [EC:2.3.1.1]" }, { "name":"R0135_07175 argJ; (GenBank) bifunctional glutamate N-acetyltransferase\/amino-acid acetyltransferase ArgJ\tK00620 argJ; glutamate N-acetyltransferase \/ amino-acid N-acetyltransferase [EC:2.3.1.35 2.3.1.1]" }, { "name":"R0135_11480 argB; (GenBank) acetylglutamate kinase\tK00930 argB; acetylglutamate kinase [EC:2.7.2.8]" }, { "name":"R0135_14665 argC; (GenBank) N-acetyl-gamma-glutamyl-phosphate reductase\tK00145 argC; N-acetyl-gamma-glutamyl-phosphate reductase [EC:1.2.1.38]" }, { "name":"R0135_09360 aspartate aminotransferase family protein\tK00821 argD; acetylornithine\/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17]" } ] }, { "name":"00330 Arginine and proline metabolism [PATH:cvb00330]", "children":[ { "name":"R0135_04300 creatininase family protein\tK01470 E3.5.2.10; creatinine amidohydrolase [EC:3.5.2.10]" }, { "name":"R0135_05580 creatininase family protein\tK01470 E3.5.2.10; creatinine amidohydrolase [EC:3.5.2.10]" }, { "name":"R0135_00135 hydantoinase\/oxoprolinase family protein\tK01473 hyuA; N-methylhydantoinase A [EC:3.5.2.14]" }, { "name":"R0135_00140 hydantoinase B\/oxoprolinase family protein\tK01474 hyuB; N-methylhydantoinase B [EC:3.5.2.14]" }, { "name":"R0135_03985 aminotransferase class I\/II-fold pyridoxal phosphate-dependent enzyme\tK01585 speA; arginine decarboxylase [EC:4.1.1.19]" }, { "name":"R0135_05245 agmatinase family protein\tK01480 speB; agmatinase [EC:3.5.3.11]" }, { "name":"R0135_12285 speB; (GenBank) agmatinase\tK01480 speB; agmatinase [EC:3.5.3.11]" }, { "name":"R0135_10970 methyltransferase domain-containing protein\tK00797 speE; spermidine synthase [EC:2.5.1.16]" }, { "name":"R0135_10765 aminotransferase\tK12256 spuC; putrescine---pyruvate transaminase [EC:2.6.1.113]" }, { "name":"R0135_03160 NAD(P)-binding protein\tK00316 spdH; spermidine dehydrogenase [EC:1.5.99.6]" }, { "name":"R0135_06470 NAD(P)-binding protein\tK00316 spdH; spermidine dehydrogenase [EC:1.5.99.6]" }, { "name":"R0135_12830 FAD\/NAD(P)-binding protein\tK00316 spdH; spermidine dehydrogenase [EC:1.5.99.6]" }, { "name":"R0135_15065 NAD(P)\/FAD-dependent oxidoreductase\tK00316 spdH; spermidine dehydrogenase [EC:1.5.99.6]" }, { "name":"R0135_01945 aldehyde dehydrogenase family protein\tK00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]" }, { "name":"R0135_15090 FAD-dependent oxidoreductase\tK00274 MAO; monoamine oxidase [EC:1.4.3.4]" }, { "name":"R0135_06955 pyridoxal phosphate-dependent aminotransferase\tK12252 aruH; arginine:pyruvate transaminase [EC:2.6.1.84]" }, { "name":"R0135_01955 speB; (GenBank) agmatinase\tK12255 gbuA; guanidinobutyrase [EC:3.5.3.7]" }, { "name":"R0135_00450 amidase family protein\tK01426 E3.5.1.4; amidase [EC:3.5.1.4]" }, { "name":"R0135_01070 amidase\tK01426 E3.5.1.4; amidase [EC:3.5.1.4]" }, { "name":"R0135_06570 amidase family protein\tK01426 E3.5.1.4; amidase [EC:3.5.1.4]" }, { "name":"R0135_08295 amidase\tK01426 E3.5.1.4; amidase [EC:3.5.1.4]" }, { "name":"R0135_13905 amidase family protein\tK01426 E3.5.1.4; amidase [EC:3.5.1.4]" }, { "name":"R0135_08955 FAD-binding oxidoreductase\tK09471 puuB; gamma-glutamylputrescine oxidase [EC:1.4.3.-]" }, { "name":"R0135_12880 FAD-binding oxidoreductase\tK09471 puuB; gamma-glutamylputrescine oxidase [EC:1.4.3.-]" }, { "name":"R0135_11370 proC; (GenBank) pyrroline-5-carboxylate reductase\tK00286 proC; pyrroline-5-carboxylate reductase [EC:1.5.1.2]" }, { "name":"R0135_13665 pyrroline-5-carboxylate reductase\tK00286 proC; pyrroline-5-carboxylate reductase [EC:1.5.1.2]" }, { "name":"R0135_13650 putA; (GenBank) bifunctional proline dehydrogenase\/L-glutamate gamma-semialdehyde dehydrogenase PutA\tK13821 putA; RHH-type transcriptional regulator, proline utilization regulon repressor \/ proline dehydrogenase \/ delta 1-pyrroline-5-carboxylate dehydrogenase [EC:1.5.5.2 1.2.1.88]" }, { "name":"R0135_13670 proB; (GenBank) glutamate 5-kinase\tK00931 proB; glutamate 5-kinase [EC:2.7.2.11]" }, { "name":"R0135_15945 proB; (GenBank) glutamate 5-kinase\tK00931 proB; glutamate 5-kinase [EC:2.7.2.11]" }, { "name":"R0135_09340 glutamate-5-semialdehyde dehydrogenase\tK00147 proA; glutamate-5-semialdehyde dehydrogenase [EC:1.2.1.41]" }, { "name":"R0135_13660 glutamate-5-semialdehyde dehydrogenase\tK00147 proA; glutamate-5-semialdehyde dehydrogenase [EC:1.2.1.41]" }, { "name":"R0135_08525 proline iminopeptidase-family hydrolase\tK01259 pip; proline iminopeptidase [EC:3.4.11.5]" }, { "name":"R0135_17115 2OG-Fe(II) oxygenase\tK00472 P4HA; prolyl 4-hydroxylase [EC:1.14.11.2]" }, { "name":"R0135_08335 amino acid aminotransferase\tK00813 aspC; aspartate aminotransferase [EC:2.6.1.1]" }, { "name":"R0135_01490 aminotransferase class IV\tK00824 dat; D-alanine transaminase [EC:2.6.1.21]" } ] }, { "name":"00340 Histidine metabolism [PATH:cvb00340]", "children":[ { "name":"R0135_07350 hisG; (GenBank) ATP phosphoribosyltransferase\tK00765 hisG; ATP phosphoribosyltransferase [EC:2.4.2.17]" }, { "name":"R0135_14995 ATP phosphoribosyltransferase regulatory subunit\tK02502 hisZ; ATP phosphoribosyltransferase regulatory subunit" }, { "name":"R0135_12610 phosphoribosyl-ATP diphosphatase\tK01523 hisE; phosphoribosyl-ATP pyrophosphohydrolase [EC:3.6.1.31]" }, { "name":"R0135_12615 hisI; (GenBank) phosphoribosyl-AMP cyclohydrolase\tK01496 hisI; phosphoribosyl-AMP cyclohydrolase [EC:3.5.4.19]" }, { "name":"R0135_12370 hisA; (GenBank) 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase\tK01814 hisA; phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase [EC:5.3.1.16]" }, { "name":"R0135_12365 hisH; (GenBank) imidazole glycerol phosphate synthase subunit HisH\tK02501 hisH; imidazole glycerol-phosphate synthase subunit HisH [EC:4.3.2.10]" }, { "name":"R0135_12375 hisF; (GenBank) imidazole glycerol phosphate synthase subunit HisF\tK02500 hisF; imidazole glycerol-phosphate synthase subunit HisF [EC:4.3.2.10]" }, { "name":"R0135_12360 hisB; (GenBank) imidazoleglycerol-phosphate dehydratase HisB\tK01693 hisB; imidazoleglycerol-phosphate dehydratase [EC:4.2.1.19]" }, { "name":"R0135_02225 hisC; (GenBank) histidinol-phosphate transaminase\tK00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]" }, { "name":"R0135_03320 histidinol-phosphate transaminase\tK00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]" }, { "name":"R0135_11175 HAD family hydrolase\tK28842 E3.1.3.15; histidinol-phosphatase [EC:3.1.3.15]" }, { "name":"R0135_07345 hisD; (GenBank) histidinol dehydrogenase\tK00013 hisD; histidinol dehydrogenase [EC:1.1.1.23]" }, { "name":"R0135_01945 aldehyde dehydrogenase family protein\tK00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]" }, { "name":"R0135_15090 FAD-dependent oxidoreductase\tK00274 MAO; monoamine oxidase [EC:1.4.3.4]" }, { "name":"R0135_13305 egtD; (GenBank) L-histidine N(alpha)-methyltransferase\tK18911 egtD; L-histidine Nalpha-methyltransferase [EC:2.1.1.44]" }, { "name":"R0135_09580 gshA; (GenBank) glutamate--cysteine ligase\tK01919 gshA; glutamate---cysteine ligase [EC:6.3.2.2]" } ] }, { "name":"00350 Tyrosine metabolism [PATH:cvb00350]", "children":[ { "name":"R0135_08335 amino acid aminotransferase\tK00813 aspC; aspartate aminotransferase [EC:2.6.1.1]" }, { "name":"R0135_02225 hisC; (GenBank) histidinol-phosphate transaminase\tK00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]" }, { "name":"R0135_03320 histidinol-phosphate transaminase\tK00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]" }, { "name":"R0135_04800 hppD; (GenBank) 4-hydroxyphenylpyruvate dioxygenase\tK00457 HPD; 4-hydroxyphenylpyruvate dioxygenase [EC:1.13.11.27]" }, { "name":"R0135_15985 homogentisate 1,2-dioxygenase\tK00451 HGD; homogentisate 1,2-dioxygenase [EC:1.13.11.5]" }, { "name":"R0135_15975 maiA; (GenBank) maleylacetoacetate isomerase\tK01800 maiA; maleylacetoacetate isomerase [EC:5.2.1.2]" }, { "name":"R0135_15980 fumarylacetoacetate hydrolase family protein\tK16171 faaH; fumarylacetoacetate (FAA) hydrolase [EC:3.7.1.2]" }, { "name":"R0135_15090 FAD-dependent oxidoreductase\tK00274 MAO; monoamine oxidase [EC:1.4.3.4]" }, { "name":"R0135_00320 S-(hydroxymethyl)glutathione dehydrogenase\/class III alcohol dehydrogenase\tK00121 frmA; S-(hydroxymethyl)glutathione dehydrogenase \/ alcohol dehydrogenase [EC:1.1.1.284 1.1.1.1]" }, { "name":"R0135_08205 fumarylacetoacetate hydrolase family protein\tK02509 hpaH; 2-oxo-hept-3-ene-1,7-dioate hydratase [EC:4.2.1.-]" }, { "name":"R0135_05945 aldolase\/citrate lyase family protein\tK02510 hpaI; 4-hydroxy-2-oxoheptanedioate aldolase [EC:4.1.2.52]" }, { "name":"R0135_08210 aldolase\/citrate lyase family protein\tK02510 hpaI; 4-hydroxy-2-oxoheptanedioate aldolase [EC:4.1.2.52]" }, { "name":"R0135_01960 NAD-dependent succinate-semialdehyde dehydrogenase\tK00135 gabD; succinate-semialdehyde dehydrogenase \/ glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]" }, { "name":"R0135_03620 fumarylacetoacetate hydrolase family protein\tK16165 nagK; fumarylpyruvate hydrolase [EC:3.7.1.20]" } ] }, { "name":"00360 Phenylalanine metabolism [PATH:cvb00360]", "children":[ { "name":"R0135_15995 aromatic amino acid hydroxylase\tK00500 phhA; phenylalanine-4-hydroxylase [EC:1.14.16.1]" }, { "name":"R0135_15090 FAD-dependent oxidoreductase\tK00274 MAO; monoamine oxidase [EC:1.4.3.4]" }, { "name":"R0135_01570 enoyl-CoA hydratase\/isomerase family protein\tK15866 paaG; 2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA isomerase [EC:5.3.3.18]" }, { "name":"R0135_09105 3-hydroxyacyl-CoA dehydrogenase NAD-binding domain-containing protein\tK00074 paaH; 3-hydroxybutyryl-CoA dehydrogenase [EC:1.1.1.157]" }, { "name":"R0135_08335 amino acid aminotransferase\tK00813 aspC; aspartate aminotransferase [EC:2.6.1.1]" }, { "name":"R0135_02225 hisC; (GenBank) histidinol-phosphate transaminase\tK00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]" }, { "name":"R0135_03320 histidinol-phosphate transaminase\tK00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]" }, { "name":"R0135_04800 hppD; (GenBank) 4-hydroxyphenylpyruvate dioxygenase\tK00457 HPD; 4-hydroxyphenylpyruvate dioxygenase [EC:1.13.11.27]" }, { "name":"R0135_01490 aminotransferase class IV\tK00824 dat; D-alanine transaminase [EC:2.6.1.21]" }, { "name":"R0135_13425 katG; (GenBank) catalase\/peroxidase HPI\tK03782 katG; catalase-peroxidase [EC:1.11.1.21]" }, { "name":"R0135_00450 amidase family protein\tK01426 E3.5.1.4; amidase [EC:3.5.1.4]" }, { "name":"R0135_01070 amidase\tK01426 E3.5.1.4; amidase [EC:3.5.1.4]" }, { "name":"R0135_06570 amidase family protein\tK01426 E3.5.1.4; amidase [EC:3.5.1.4]" }, { "name":"R0135_08295 amidase\tK01426 E3.5.1.4; amidase [EC:3.5.1.4]" }, { "name":"R0135_13905 amidase family protein\tK01426 E3.5.1.4; amidase [EC:3.5.1.4]" }, { "name":"R0135_10625 hypothetical protein\tK02554 mhpD; 2-keto-4-pentenoate hydratase [EC:4.2.1.80]" } ] }, { "name":"00380 Tryptophan metabolism [PATH:cvb00380]", "children":[ { "name":"R0135_04610 kynU; (GenBank) kynureninase\tK01556 KYNU; kynureninase [EC:3.7.1.3]" }, { "name":"R0135_10425 aminotransferase class V-fold PLP-dependent enzyme\tK01556 KYNU; kynureninase [EC:3.7.1.3]" }, { "name":"R0135_02265 odhB; (GenBank) 2-oxoglutarate dehydrogenase complex dihydrolipoyllysine-residue succinyltransferase\tK00658 DLST; 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61]" }, { "name":"R0135_02270 lpdA; (GenBank) dihydrolipoyl dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]" }, { "name":"R0135_10745 acyl-CoA dehydrogenase\tK00252 GCDH; glutaryl-CoA dehydrogenase [EC:1.3.8.6]" }, { "name":"R0135_09395 fadB; (GenBank) fatty acid oxidation complex subunit alpha FadB\tK01825 fadB; 3-hydroxyacyl-CoA dehydrogenase \/ enoyl-CoA hydratase \/ 3-hydroxybutyryl-CoA epimerase \/ enoyl-CoA isomerase [EC:1.1.1.35 4.2.1.17 5.1.2.3 5.3.3.8]" }, { "name":"R0135_00335 3-hydroxyacyl-CoA dehydrogenase NAD-binding domain-containing protein\tK01782 fadJ; 3-hydroxyacyl-CoA dehydrogenase \/ enoyl-CoA hydratase \/ 3-hydroxybutyryl-CoA epimerase [EC:1.1.1.35 4.2.1.17 5.1.2.3]" }, { "name":"R0135_00330 acetyl-CoA C-acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" }, { "name":"R0135_03970 acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" }, { "name":"R0135_04435 acetyl-CoA C-acyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" }, { "name":"R0135_05075 acetyl-CoA C-acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" }, { "name":"R0135_11080 acetyl-CoA C-acyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" }, { "name":"R0135_11085 acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" }, { "name":"R0135_15090 FAD-dependent oxidoreductase\tK00274 MAO; monoamine oxidase [EC:1.4.3.4]" }, { "name":"R0135_01945 aldehyde dehydrogenase family protein\tK00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]" }, { "name":"R0135_04505 carbon-nitrogen hydrolase family protein\tK01501 E3.5.5.1; nitrilase [EC:3.5.5.1]" }, { "name":"R0135_00450 amidase family protein\tK01426 E3.5.1.4; amidase [EC:3.5.1.4]" }, { "name":"R0135_01070 amidase\tK01426 E3.5.1.4; amidase [EC:3.5.1.4]" }, { "name":"R0135_06570 amidase family protein\tK01426 E3.5.1.4; amidase [EC:3.5.1.4]" }, { "name":"R0135_08295 amidase\tK01426 E3.5.1.4; amidase [EC:3.5.1.4]" }, { "name":"R0135_13905 amidase family protein\tK01426 E3.5.1.4; amidase [EC:3.5.1.4]" }, { "name":"R0135_13425 katG; (GenBank) catalase\/peroxidase HPI\tK03782 katG; catalase-peroxidase [EC:1.11.1.21]" } ] }, { "name":"00400 Phenylalanine, tyrosine and tryptophan biosynthesis [PATH:cvb00400]", "children":[ { "name":"R0135_01405 3-deoxy-7-phosphoheptulonate synthase\tK01626 E2.5.1.54; 3-deoxy-7-phosphoheptulonate synthase [EC:2.5.1.54]" }, { "name":"R0135_02970 3-deoxy-7-phosphoheptulonate synthase\tK01626 E2.5.1.54; 3-deoxy-7-phosphoheptulonate synthase [EC:2.5.1.54]" }, { "name":"R0135_10855 3-deoxy-7-phosphoheptulonate synthase\tK01626 E2.5.1.54; 3-deoxy-7-phosphoheptulonate synthase [EC:2.5.1.54]" }, { "name":"R0135_12725 aroB; (GenBank) 3-dehydroquinate synthase\tK01735 aroB; 3-dehydroquinate synthase [EC:4.2.3.4]" }, { "name":"R0135_14590 aroQ; (GenBank) type II 3-dehydroquinate dehydratase\tK03786 aroQ; 3-dehydroquinate dehydratase II [EC:4.2.1.10]" }, { "name":"R0135_11930 aroE; (GenBank) shikimate dehydrogenase\tK00014 aroE; shikimate dehydrogenase [EC:1.1.1.25]" }, { "name":"R0135_13920 PQQ-binding-like beta-propeller repeat protein\tK05358 quiA; quinate dehydrogenase (quinone) [EC:1.1.5.8]" }, { "name":"R0135_12720 aroK; (GenBank) shikimate kinase AroK\tK00891 aroK; shikimate kinase [EC:2.7.1.71]" }, { "name":"R0135_12900 shikimate kinase\tK00891 aroK; shikimate kinase [EC:2.7.1.71]" }, { "name":"R0135_06795 aroA; (GenBank) 3-phosphoshikimate 1-carboxyvinyltransferase\tK00800 aroA; 3-phosphoshikimate 1-carboxyvinyltransferase [EC:2.5.1.19]" }, { "name":"R0135_02305 aroC; (GenBank) chorismate synthase\tK01736 aroC; chorismate synthase [EC:4.2.3.5]" }, { "name":"R0135_14520 trpE; (GenBank) anthranilate synthase component I\tK01657 trpE; anthranilate synthase component I [EC:4.1.3.27]" }, { "name":"R0135_14525 aminodeoxychorismate\/anthranilate synthase component II\tK01658 trpG; anthranilate synthase component II [EC:4.1.3.27]" }, { "name":"R0135_14530 trpD; (GenBank) anthranilate phosphoribosyltransferase\tK00766 trpD; anthranilate phosphoribosyltransferase [EC:2.4.2.18]" }, { "name":"R0135_03870 phosphoribosylanthranilate isomerase\tK01817 trpF; phosphoribosylanthranilate isomerase [EC:5.3.1.24]" }, { "name":"R0135_14535 trpC; (GenBank) indole-3-glycerol phosphate synthase TrpC\tK01609 trpC; indole-3-glycerol phosphate synthase [EC:4.1.1.48]" }, { "name":"R0135_03860 trpA; (GenBank) tryptophan synthase subunit alpha\tK01695 trpA; tryptophan synthase alpha chain [EC:4.2.1.20]" }, { "name":"R0135_03865 trpB; (GenBank) tryptophan synthase subunit beta\tK01696 trpB; tryptophan synthase beta chain [EC:4.2.1.20]" }, { "name":"R0135_06805 pheA; (GenBank) prephenate dehydratase\tK14170 pheA; chorismate mutase \/ prephenate dehydratase [EC:5.4.99.5 4.2.1.51]" }, { "name":"R0135_08335 amino acid aminotransferase\tK00813 aspC; aspartate aminotransferase [EC:2.6.1.1]" }, { "name":"R0135_02225 hisC; (GenBank) histidinol-phosphate transaminase\tK00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]" }, { "name":"R0135_03320 histidinol-phosphate transaminase\tK00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]" }, { "name":"R0135_15995 aromatic amino acid hydroxylase\tK00500 phhA; phenylalanine-4-hydroxylase [EC:1.14.16.1]" } ] } ] }, { "name":"09106 Metabolism of other amino acids", "children":[ { "name":"00410 beta-Alanine metabolism [PATH:cvb00410]", "children":[ { "name":"R0135_03160 NAD(P)-binding protein\tK00316 spdH; spermidine dehydrogenase [EC:1.5.99.6]" }, { "name":"R0135_06470 NAD(P)-binding protein\tK00316 spdH; spermidine dehydrogenase [EC:1.5.99.6]" }, { "name":"R0135_12830 FAD\/NAD(P)-binding protein\tK00316 spdH; spermidine dehydrogenase [EC:1.5.99.6]" }, { "name":"R0135_15065 NAD(P)\/FAD-dependent oxidoreductase\tK00316 spdH; spermidine dehydrogenase [EC:1.5.99.6]" }, { "name":"R0135_01945 aldehyde dehydrogenase family protein\tK00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]" }, { "name":"R0135_08650 panC; (GenBank) pantoate--beta-alanine ligase\tK01918 panC; pantoate--beta-alanine ligase [EC:6.3.2.1]" }, { "name":"R0135_06435 Zn-dependent hydrolase\tK06016 pydC; beta-ureidopropionase \/ N-carbamoyl-L-amino-acid hydrolase [EC:3.5.1.6 3.5.1.87]" }, { "name":"R0135_13385 Zn-dependent hydrolase\tK06016 pydC; beta-ureidopropionase \/ N-carbamoyl-L-amino-acid hydrolase [EC:3.5.1.6 3.5.1.87]" }, { "name":"R0135_08990 aspartate aminotransferase family protein\tK00822 E2.6.1.18; beta-alanine--pyruvate transaminase [EC:2.6.1.18]" }, { "name":"R0135_09395 fadB; (GenBank) fatty acid oxidation complex subunit alpha FadB\tK01825 fadB; 3-hydroxyacyl-CoA dehydrogenase \/ enoyl-CoA hydratase \/ 3-hydroxybutyryl-CoA epimerase \/ enoyl-CoA isomerase [EC:1.1.1.35 4.2.1.17 5.1.2.3 5.3.3.8]" }, { "name":"R0135_00335 3-hydroxyacyl-CoA dehydrogenase NAD-binding domain-containing protein\tK01782 fadJ; 3-hydroxyacyl-CoA dehydrogenase \/ enoyl-CoA hydratase \/ 3-hydroxybutyryl-CoA epimerase [EC:1.1.1.35 4.2.1.17 5.1.2.3]" }, { "name":"R0135_10955 CoA-acylating methylmalonate-semialdehyde dehydrogenase\tK00140 mmsA; malonate-semialdehyde dehydrogenase (acetylating) \/ methylmalonate-semialdehyde dehydrogenase [EC:1.2.1.18 1.2.1.27]" } ] }, { "name":"00430 Taurine and hypotaurine metabolism [PATH:cvb00430]", "children":[ { "name":"R0135_05260 gamma-glutamyltransferase\tK00681 ggt; gamma-glutamyltranspeptidase \/ glutathione hydrolase [EC:2.3.2.2 3.4.19.13]" }, { "name":"R0135_12675 ggt; (GenBank) gamma-glutamyltransferase\tK00681 ggt; gamma-glutamyltranspeptidase \/ glutathione hydrolase [EC:2.3.2.2 3.4.19.13]" }, { "name":"R0135_15070 ggt; (GenBank) gamma-glutamyltransferase\tK00681 ggt; gamma-glutamyltranspeptidase \/ glutathione hydrolase [EC:2.3.2.2 3.4.19.13]" }, { "name":"R0135_16000 tauD; (GenBank) taurine dioxygenase\tK03119 tauD; taurine dioxygenase [EC:1.14.11.17]" }, { "name":"R0135_07130 ald; (GenBank) alanine dehydrogenase\tK00259 ald; alanine dehydrogenase [EC:1.4.1.1]" }, { "name":"R0135_04195 NAD-glutamate dehydrogenase\tK15371 GDH2; glutamate dehydrogenase [EC:1.4.1.2]" } ] }, { "name":"00440 Phosphonate and phosphinate metabolism" }, { "name":"00450 Selenocompound metabolism [PATH:cvb00450]", "children":[ { "name":"R0135_05585 metC; (GenBank) cystathionine beta-lyase\tK01760 metC; cysteine-S-conjugate beta-lyase [EC:4.4.1.13]" }, { "name":"R0135_02980 metH; (GenBank) methionine synthase\tK00548 metH; 5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]" }, { "name":"R0135_10000 cysteine desulfurase\tK11717 sufS; cysteine desulfurase \/ selenocysteine lyase [EC:2.8.1.7 4.4.1.16]" }, { "name":"R0135_02655 trxB; (GenBank) thioredoxin-disulfide reductase\tK00384 trxB; thioredoxin reductase (NADPH) [EC:1.8.1.9]" }, { "name":"R0135_07045 sat; (GenBank) sulfate adenylyltransferase\tK00958 sat; sulfate adenylyltransferase [EC:2.7.7.4]" }, { "name":"R0135_17395 metG; (GenBank) methionine--tRNA ligase\tK01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]" } ] }, { "name":"00460 Cyanoamino acid metabolism [PATH:cvb00460]", "children":[ { "name":"R0135_05190 bglX; (GenBank) beta-glucosidase BglX\tK05349 bglX; beta-glucosidase [EC:3.2.1.21]" }, { "name":"R0135_05195 glycoside hydrolase family 3 protein\tK05349 bglX; beta-glucosidase [EC:3.2.1.21]" }, { "name":"R0135_13810 glycoside hydrolase family 3 N-terminal domain-containing protein\tK05349 bglX; beta-glucosidase [EC:3.2.1.21]" }, { "name":"R0135_04505 carbon-nitrogen hydrolase family protein\tK01501 E3.5.5.1; nitrilase [EC:3.5.5.1]" }, { "name":"R0135_05260 gamma-glutamyltransferase\tK00681 ggt; gamma-glutamyltranspeptidase \/ glutathione hydrolase [EC:2.3.2.2 3.4.19.13]" }, { "name":"R0135_12675 ggt; (GenBank) gamma-glutamyltransferase\tK00681 ggt; gamma-glutamyltranspeptidase \/ glutathione hydrolase [EC:2.3.2.2 3.4.19.13]" }, { "name":"R0135_15070 ggt; (GenBank) gamma-glutamyltransferase\tK00681 ggt; gamma-glutamyltranspeptidase \/ glutathione hydrolase [EC:2.3.2.2 3.4.19.13]" }, { "name":"R0135_03965 asparaginase domain-containing protein\tK01424 E3.5.1.1; L-asparaginase [EC:3.5.1.1]" }, { "name":"R0135_12670 asparaginase\tK01424 E3.5.1.1; L-asparaginase [EC:3.5.1.1]" }, { "name":"R0135_15430 glyA; (GenBank) serine hydroxymethyltransferase\tK00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]" }, { "name":"R0135_12330 acetamidase\/formamidase family protein\tK01455 fmdA; formamidase [EC:3.5.1.49]" } ] }, { "name":"00470 D-Amino acid metabolism [PATH:cvb00470]", "children":[ { "name":"R0135_01485 alr; (GenBank) alanine racemase\tK01775 alr; alanine racemase [EC:5.1.1.1]" }, { "name":"R0135_01490 aminotransferase class IV\tK00824 dat; D-alanine transaminase [EC:2.6.1.21]" }, { "name":"R0135_07205 D-alanine--D-alanine ligase\tK01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]" }, { "name":"R0135_07225 murD; (GenBank) UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase\tK01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9]" }, { "name":"R0135_05050 DUF1611 domain-containing protein\tK26272 dgcN; D-glutamate N-acetyltransferase [EC:2.3.1.312]" }, { "name":"R0135_05055 dipeptide epimerase\tK19802 ycjG; L-Ala-D\/L-Glu epimerase \/ N-acetyl-D-glutamate racemase [EC:5.1.1.20 5.1.1.25]" }, { "name":"R0135_04080 amino acid racemase\tK01779 racD; aspartate racemase [EC:5.1.1.13]" }, { "name":"R0135_09680 dapF; (GenBank) diaminopimelate epimerase\tK01778 dapF; diaminopimelate epimerase [EC:5.1.1.7]" }, { "name":"R0135_04540 alanine racemase\tK01586 lysA; diaminopimelate decarboxylase [EC:4.1.1.20]" }, { "name":"R0135_09675 lysA; (GenBank) diaminopimelate decarboxylase\tK01586 lysA; diaminopimelate decarboxylase [EC:4.1.1.20]" } ] }, { "name":"00480 Glutathione metabolism [PATH:cvb00480]", "children":[ { "name":"R0135_05260 gamma-glutamyltransferase\tK00681 ggt; gamma-glutamyltranspeptidase \/ glutathione hydrolase [EC:2.3.2.2 3.4.19.13]" }, { "name":"R0135_12675 ggt; (GenBank) gamma-glutamyltransferase\tK00681 ggt; gamma-glutamyltranspeptidase \/ glutathione hydrolase [EC:2.3.2.2 3.4.19.13]" }, { "name":"R0135_15070 ggt; (GenBank) gamma-glutamyltransferase\tK00681 ggt; gamma-glutamyltranspeptidase \/ glutathione hydrolase [EC:2.3.2.2 3.4.19.13]" }, { "name":"R0135_05510 gamma-glutamylcyclotransferase\tK07232 CHAC; glutathione-specific gamma-glutamylcyclotransferase [EC:4.3.2.7]" }, { "name":"R0135_01510 5-oxoprolinase subunit PxpA\tK07160 pxpA; 5-oxoprolinase (ATP-hydrolysing) subunit A [EC:3.5.2.9]" }, { "name":"R0135_09580 gshA; (GenBank) glutamate--cysteine ligase\tK01919 gshA; glutamate---cysteine ligase [EC:6.3.2.2]" }, { "name":"R0135_11335 gshB; (GenBank) glutathione synthase\tK01920 gshB; glutathione synthase [EC:6.3.2.3]" }, { "name":"R0135_01625 leucyl aminopeptidase\tK01255 CARP; leucyl aminopeptidase [EC:3.4.11.1]" }, { "name":"R0135_04230 pepN; (GenBank) aminopeptidase N\tK01256 pepN; aminopeptidase N [EC:3.4.11.2]" }, { "name":"R0135_13605 M1 family aminopeptidase\tK01256 pepN; aminopeptidase N [EC:3.4.11.2]" }, { "name":"R0135_05625 glutathione S-transferase family protein\tK00799 GST; glutathione S-transferase [EC:2.5.1.18]" }, { "name":"R0135_05650 glutathione S-transferase\tK00799 GST; glutathione S-transferase [EC:2.5.1.18]" }, { "name":"R0135_09785 glutathione S-transferase family protein\tK00799 GST; glutathione S-transferase [EC:2.5.1.18]" }, { "name":"R0135_10085 glutathione S-transferase family protein\tK00799 GST; glutathione S-transferase [EC:2.5.1.18]" }, { "name":"R0135_13800 glutathione S-transferase family protein\tK00799 GST; glutathione S-transferase [EC:2.5.1.18]" }, { "name":"R0135_13890 glutathione S-transferase family protein\tK00799 GST; glutathione S-transferase [EC:2.5.1.18]" }, { "name":"R0135_14040 MAPEG family protein\tK00799 GST; glutathione S-transferase [EC:2.5.1.18]" }, { "name":"R0135_10875 gor; (GenBank) glutathione-disulfide reductase\tK00383 GSR; glutathione reductase (NADPH) [EC:1.8.1.7]" }, { "name":"R0135_02625 icd; (GenBank) NADP-dependent isocitrate dehydrogenase\tK00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]" }, { "name":"R0135_04930 isocitrate\/isopropylmalate family dehydrogenase\tK00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]" }, { "name":"R0135_05140 zwf; (GenBank) glucose-6-phosphate dehydrogenase\tK00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363]" }, { "name":"R0135_09280 glutathione peroxidase\tK00432 gpx; glutathione peroxidase [EC:1.11.1.9]" }, { "name":"R0135_09525 peroxiredoxin\tK24138 prx3; glutaredoxin\/glutathione-dependent peroxiredoxin [EC:1.11.1.25 1.11.1.27]" }, { "name":"R0135_10970 methyltransferase domain-containing protein\tK00797 speE; spermidine synthase [EC:2.5.1.16]" } ] } ] }, { "name":"09107 Glycan biosynthesis and metabolism", "children":[ { "name":"00520 Amino sugar and nucleotide sugar metabolism [PATH:cvb00520]", "children":[ { "name":"R0135_14675 anhydro-N-acetylmuramic acid kinase\tK09001 anmK; anhydro-N-acetylmuramic acid kinase [EC:2.7.1.170]" }, { "name":"R0135_06830 HAD-IA family hydrolase\tK22292 mupP; N-acetyl-D-muramate 6-phosphate phosphatase [EC:3.1.3.105]" }, { "name":"R0135_14505 phosphotransferase\tK07102 amgK; N-acetylmuramate 1-kinase [EC:2.7.1.221]" }, { "name":"R0135_14510 nucleotidyltransferase family protein\tK00992 murU; N-acetyl-alpha-D-muramate 1-phosphate uridylyltransferase [EC:2.7.7.99]" }, { "name":"R0135_11640 glmU; (GenBank) bifunctional UDP-N-acetylglucosamine diphosphorylase\/glucosamine-1-phosphate N-acetyltransferase GlmU\tK04042 glmU; bifunctional UDP-N-acetylglucosamine pyrophosphorylase \/ glucosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.3.1.157]" }, { "name":"R0135_07355 murA; (GenBank) UDP-N-acetylglucosamine 1-carboxyvinyltransferase\tK00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7]" }, { "name":"R0135_03400 murB; (GenBank) UDP-N-acetylmuramate dehydrogenase\tK00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98]" }, { "name":"R0135_08720 glmM; (GenBank) phosphoglucosamine mutase\tK03431 glmM; phosphoglucosamine mutase [EC:5.4.2.10]" }, { "name":"R0135_11635 glmS; (GenBank) glutamine--fructose-6-phosphate transaminase (isomerizing)\tK00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]" }, { "name":"R0135_00520 ROK family protein\tK00847 E2.7.1.4; fructokinase [EC:2.7.1.4]" }, { "name":"R0135_11775 carbohydrate kinase\tK00847 E2.7.1.4; fructokinase [EC:2.7.1.4]" }, { "name":"R0135_04165 pgi; (GenBank) glucose-6-phosphate isomerase\tK01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]" }, { "name":"R0135_15910 mannose-1-phosphate guanylyltransferase\/mannose-6-phosphate isomerase\tK16011 algA; mannose-1-phosphate guanylyltransferase \/ mannose-6-phosphate isomerase [EC:2.7.7.13 5.3.1.8]" }, { "name":"R0135_00505 NAD-dependent epimerase\tK08679 GAE; UDP-glucuronate 4-epimerase [EC:5.1.3.6]" }, { "name":"R0135_05150 glk; (GenBank) glucokinase\tK00845 glk; glucokinase [EC:2.7.1.2]" }, { "name":"R0135_11475 phosphomannomutase\/phosphoglucomutase\tK15778 pmm-pgm; phosphomannomutase \/ phosphoglucomutase [EC:5.4.2.8 5.4.2.2]" }, { "name":"R0135_15915 galU; (GenBank) UTP--glucose-1-phosphate uridylyltransferase GalU\tK00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]" }, { "name":"R0135_00500 UDP-glucose\/GDP-mannose dehydrogenase family protein\tK00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]" }, { "name":"R0135_05100 galK; (GenBank) galactokinase\tK00849 galK; galactokinase [EC:2.7.1.6]" }, { "name":"R0135_05105 UDP-glucose--hexose-1-phosphate uridylyltransferase\tK00965 galT; UDPglucose--hexose-1-phosphate uridylyltransferase [EC:2.7.7.12]" }, { "name":"R0135_00510 galE; (GenBank) UDP-glucose 4-epimerase GalE\tK01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2]" }, { "name":"R0135_15920 phosphomannomutase\tK01840 manB; phosphomannomutase [EC:5.4.2.8]" }, { "name":"R0135_12120 rfbA; (GenBank) glucose-1-phosphate thymidylyltransferase RfbA\tK00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]" } ] }, { "name":"00541 Biosynthesis of various nucleotide sugars [PATH:cvb00541]", "children":[ { "name":"R0135_11640 glmU; (GenBank) bifunctional UDP-N-acetylglucosamine diphosphorylase\/glucosamine-1-phosphate N-acetyltransferase GlmU\tK04042 glmU; bifunctional UDP-N-acetylglucosamine pyrophosphorylase \/ glucosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.3.1.157]" }, { "name":"R0135_07820 nucleotide sugar dehydrogenase\tK02474 wbpO; UDP-N-acetyl-D-glucosamine\/UDP-N-acetyl-D-galactosamine dehydrogenase [EC:1.1.1.136 1.1.1.-]" }, { "name":"R0135_06745 nucleoside-diphosphate sugar epimerase\/dehydratase\tK24300 wbpM; UDP-N-acetylglucosamine 4,6-dehydratase [EC:4.2.1.135]" }, { "name":"R0135_07375 KpsF\/GutQ family sugar-phosphate isomerase\tK06041 kdsD; arabinose-5-phosphate isomerase [EC:5.3.1.13]" }, { "name":"R0135_05395 kdsA; (GenBank) 3-deoxy-8-phosphooctulonate synthase\tK01627 kdsA; 2-dehydro-3-deoxyphosphooctonate aldolase (KDO 8-P synthase) [EC:2.5.1.55]" }, { "name":"R0135_07380 HAD-IIIA family hydrolase\tK03270 kdsC; 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (KDO 8-P phosphatase) [EC:3.1.3.45]" }, { "name":"R0135_03405 kdsB; (GenBank) 3-deoxy-manno-octulosonate cytidylyltransferase\tK00979 kdsB; 3-deoxy-manno-octulosonate cytidylyltransferase (CMP-KDO synthetase) [EC:2.7.7.38]" }, { "name":"R0135_07285 phosphoheptose isomerase\tK03271 gmhA; D-sedoheptulose 7-phosphate isomerase [EC:5.3.1.28]" }, { "name":"R0135_15915 galU; (GenBank) UTP--glucose-1-phosphate uridylyltransferase GalU\tK00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]" }, { "name":"R0135_00500 UDP-glucose\/GDP-mannose dehydrogenase family protein\tK00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]" }, { "name":"R0135_12120 rfbA; (GenBank) glucose-1-phosphate thymidylyltransferase RfbA\tK00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]" }, { "name":"R0135_12105 rfbB; (GenBank) dTDP-glucose 4,6-dehydratase\tK01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]" }, { "name":"R0135_12115 rfbC; (GenBank) dTDP-4-dehydrorhamnose 3,5-epimerase\tK01790 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase [EC:5.1.3.13]" }, { "name":"R0135_12100 rfbD; (GenBank) dTDP-4-dehydrorhamnose reductase\tK00067 rfbD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133]" }, { "name":"R0135_15885 sugar nucleotide-binding protein\tK00067 rfbD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133]" }, { "name":"R0135_15910 mannose-1-phosphate guanylyltransferase\/mannose-6-phosphate isomerase\tK16011 algA; mannose-1-phosphate guanylyltransferase \/ mannose-6-phosphate isomerase [EC:2.7.7.13 5.3.1.8]" }, { "name":"R0135_03805 gmd; (GenBank) GDP-mannose 4,6-dehydratase\tK01711 gmd; GDPmannose 4,6-dehydratase [EC:4.2.1.47]" }, { "name":"R0135_03800 GDP-L-fucose synthase\tK02377 TSTA3; GDP-L-fucose synthase [EC:1.1.1.271]" } ] }, { "name":"00510 N-Glycan biosynthesis" }, { "name":"00513 Various types of N-glycan biosynthesis" }, { "name":"00512 Mucin type O-glycan biosynthesis" }, { "name":"00515 Mannose type O-glycan biosynthesis" }, { "name":"00514 Other types of O-glycan biosynthesis" }, { "name":"00532 Glycosaminoglycan biosynthesis - chondroitin sulfate \/ dermatan sulfate" }, { "name":"00534 Glycosaminoglycan biosynthesis - heparan sulfate \/ heparin" }, { "name":"00533 Glycosaminoglycan biosynthesis - keratan sulfate" }, { "name":"00531 Glycosaminoglycan degradation" }, { "name":"00563 Glycosylphosphatidylinositol (GPI)-anchor biosynthesis" }, { "name":"00601 Glycosphingolipid biosynthesis - lacto and neolacto series" }, { "name":"00603 Glycosphingolipid biosynthesis - globo and isoglobo series" }, { "name":"00604 Glycosphingolipid biosynthesis - ganglio series" }, { "name":"00511 Other glycan degradation" }, { "name":"00540 Lipopolysaccharide biosynthesis [PATH:cvb00540]", "children":[ { "name":"R0135_00085 lpxA; (GenBank) acyl-ACP--UDP-N-acetylglucosamine O-acyltransferase\tK00677 lpxA; UDP-N-acetylglucosamine acyltransferase [EC:2.3.1.129]" }, { "name":"R0135_07185 lpxC; (GenBank) UDP-3-O-acyl-N-acetylglucosamine deacetylase\tK02535 lpxC; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [EC:3.5.1.108]" }, { "name":"R0135_00075 lpxD; (GenBank) UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase\tK02536 lpxD; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase [EC:2.3.1.191]" }, { "name":"R0135_03655 UDP-2,3-diacylglucosamine diphosphatase\tK03269 lpxH; UDP-2,3-diacylglucosamine hydrolase [EC:3.6.1.54]" }, { "name":"R0135_00090 lpxB; (GenBank) lipid-A-disaccharide synthase\tK00748 lpxB; lipid-A-disaccharide synthase [EC:2.4.1.182]" }, { "name":"R0135_03410 lpxK; (GenBank) tetraacyldisaccharide 4'-kinase\tK00912 lpxK; tetraacyldisaccharide 4'-kinase [EC:2.7.1.130]" }, { "name":"R0135_12150 waaA; (GenBank) lipid IV(A) 3-deoxy-D-manno-octulosonic acid transferase\tK02527 kdtA; 3-deoxy-D-manno-octulosonic-acid transferase [EC:2.4.99.12 2.4.99.13 2.4.99.14 2.4.99.15]" }, { "name":"R0135_11840 lysophospholipid acyltransferase family protein\tK02517 lpxL; Kdo2-lipid IVA lauroyltransferase\/acyltransferase [EC:2.3.1.241 2.3.1.-]" }, { "name":"R0135_13050 lysophospholipid acyltransferase family protein\tK02517 lpxL; Kdo2-lipid IVA lauroyltransferase\/acyltransferase [EC:2.3.1.241 2.3.1.-]" } ] }, { "name":"00542 O-Antigen repeat unit biosynthesis [PATH:cvb00542]", "children":[ { "name":"R0135_03755 hypothetical protein\tK02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate\/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35]" } ] }, { "name":"00550 Peptidoglycan biosynthesis [PATH:cvb00550]", "children":[ { "name":"R0135_07355 murA; (GenBank) UDP-N-acetylglucosamine 1-carboxyvinyltransferase\tK00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7]" }, { "name":"R0135_03400 murB; (GenBank) UDP-N-acetylmuramate dehydrogenase\tK00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98]" }, { "name":"R0135_07210 murC; (GenBank) UDP-N-acetylmuramate--L-alanine ligase\tK01924 murC; UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8]" }, { "name":"R0135_07225 murD; (GenBank) UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase\tK01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9]" }, { "name":"R0135_07240 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase\tK01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13]" }, { "name":"R0135_07205 D-alanine--D-alanine ligase\tK01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]" }, { "name":"R0135_07235 murF; (GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase\tK01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10]" }, { "name":"R0135_00045 uppS; (GenBank) polyprenyl diphosphate synthase\tK00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31]" }, { "name":"R0135_01865 undecaprenyl-diphosphate phosphatase\tK06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27]" }, { "name":"R0135_07230 mraY; (GenBank) phospho-N-acetylmuramoyl-pentapeptide-transferase\tK01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13]" }, { "name":"R0135_07215 murG; (GenBank) undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase\tK02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227]" }, { "name":"R0135_12690 penicillin-binding protein 1A\tK05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4]" }, { "name":"R0135_14620 mrcB; (GenBank) penicillin-binding protein 1B\tK05365 mrcB; penicillin-binding protein 1B [EC:2.4.99.28 3.4.16.4]" }, { "name":"R0135_07220 ftsW; (GenBank) putative lipid II flippase FtsW\tK03588 ftsW; peptidoglycan glycosyltransferase [EC:2.4.99.28]" }, { "name":"R0135_09315 rodA; (GenBank) rod shape-determining protein RodA\tK05837 rodA; peptidoglycan glycosyltransferase [EC:2.4.99.28]" }, { "name":"R0135_09320 mrdA; (GenBank) penicillin-binding protein 2\tK05515 mrdA; penicillin-binding protein 2 [EC:3.4.16.4]" }, { "name":"R0135_07245 penicillin-binding protein 2\tK03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4]" }, { "name":"R0135_09300 D-alanyl-D-alanine carboxypeptidase family protein\tK07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5\/6) [EC:3.4.16.4]" } ] }, { "name":"00552 Teichoic acid biosynthesis [PATH:cvb00552]", "children":[ { "name":"R0135_01865 undecaprenyl-diphosphate phosphatase\tK06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27]" }, { "name":"R0135_03755 hypothetical protein\tK02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate\/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35]" }, { "name":"R0135_06745 nucleoside-diphosphate sugar epimerase\/dehydratase\tK24300 wbpM; UDP-N-acetylglucosamine 4,6-dehydratase [EC:4.2.1.135]" } ] }, { "name":"00571 Lipoarabinomannan (LAM) biosynthesis" }, { "name":"00572 Arabinogalactan biosynthesis - Mycobacterium", "children":[ { "name":"R0135_03755 hypothetical protein\tK02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate\/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35]" } ] }, { "name":"00543 Exopolysaccharide biosynthesis [PATH:cvb00543]", "children":[ { "name":"R0135_03755 hypothetical protein\tK02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate\/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35]" }, { "name":"R0135_08465 MBOAT family protein\tK19294 algI; alginate O-acetyltransferase complex protein AlgI" }, { "name":"R0135_12745 cysE; (GenBank) serine O-acetyltransferase\tK00640 cysE; serine O-acetyltransferase [EC:2.3.1.30]" } ] } ] }, { "name":"09108 Metabolism of cofactors and vitamins", "children":[ { "name":"00730 Thiamine metabolism [PATH:cvb00730]", "children":[ { "name":"R0135_00960 IscS subfamily cysteine desulfurase\tK04487 iscS; cysteine desulfurase [EC:2.8.1.7]" }, { "name":"R0135_15510 dxs; (GenBank) 1-deoxy-D-xylulose-5-phosphate synthase\tK01662 dxs; 1-deoxy-D-xylulose-5-phosphate synthase [EC:2.2.1.7]" }, { "name":"R0135_15465 thiL; (GenBank) thiamine-phosphate kinase\tK00946 thiL; thiamine-monophosphate kinase [EC:2.7.4.16]" }, { "name":"R0135_14930 rsgA; (GenBank) small ribosomal subunit biogenesis GTPase RsgA\tK06949 rsgA; ribosome biogenesis GTPase \/ thiamine phosphate phosphatase [EC:3.6.1.- 3.1.3.100]" }, { "name":"R0135_10725 alkaline phosphatase\tK01077 ALP; alkaline phosphatase [EC:3.1.3.1]" }, { "name":"R0135_01850 adk; (GenBank) adenylate kinase\tK00939 adk; adenylate kinase [EC:2.7.4.3]" } ] }, { "name":"00740 Riboflavin metabolism [PATH:cvb00740]", "children":[ { "name":"R0135_15480 ribA; (GenBank) GTP cyclohydrolase II\tK01497 ribA; GTP cyclohydrolase II [EC:3.5.4.25]" }, { "name":"R0135_04440 ribB; (GenBank) 3,4-dihydroxy-2-butanone-4-phosphate synthase\tK14652 ribBA; 3,4-dihydroxy 2-butanone 4-phosphate synthase \/ GTP cyclohydrolase II [EC:4.1.99.12 3.5.4.25]" }, { "name":"R0135_15450 ribB; (GenBank) 3,4-dihydroxy-2-butanone-4-phosphate synthase\tK14652 ribBA; 3,4-dihydroxy 2-butanone 4-phosphate synthase \/ GTP cyclohydrolase II [EC:4.1.99.12 3.5.4.25]" }, { "name":"R0135_15440 ribD; (GenBank) bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase\/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD\tK11752 ribD; diaminohydroxyphosphoribosylaminopyrimidine deaminase \/ 5-amino-6-(5-phosphoribosylamino)uracil reductase [EC:3.5.4.26 1.1.1.193]" }, { "name":"R0135_09695 HAD-IA family hydrolase\tK20862 yigB; FMN hydrolase \/ 5-amino-6-(5-phospho-D-ribitylamino)uracil phosphatase [EC:3.1.3.102 3.1.3.104]" }, { "name":"R0135_15455 ribE; (GenBank) 6,7-dimethyl-8-ribityllumazine synthase\tK00794 ribH; 6,7-dimethyl-8-ribityllumazine synthase [EC:2.5.1.78]" }, { "name":"R0135_15445 riboflavin synthase\tK00793 ribE; riboflavin synthase [EC:2.5.1.9]" }, { "name":"R0135_16975 ribF; (GenBank) bifunctional riboflavin kinase\/FAD synthetase\tK11753 ribF; riboflavin kinase \/ FMN adenylyltransferase [EC:2.7.1.26 2.7.7.2]" }, { "name":"R0135_16965 NUDIX domain-containing protein\tK01515 nudF; ADP-ribose diphosphatase [EC:3.6.1.13 3.6.1.-]" }, { "name":"R0135_10995 UbiX family flavin prenyltransferase\tK03186 ubiX; flavin prenyltransferase [EC:2.5.1.129]" } ] }, { "name":"00750 Vitamin B6 metabolism [PATH:cvb00750]", "children":[ { "name":"R0135_14885 pdxH; (GenBank) pyridoxamine 5'-phosphate oxidase\tK00275 pdxH; pyridoxamine 5'-phosphate oxidase [EC:1.4.3.5]" }, { "name":"R0135_11300 glyceraldehyde 3-phosphate dehydrogenase NAD-binding domain-containing protein\tK03472 epd; D-erythrose 4-phosphate dehydrogenase [EC:1.2.1.72]" }, { "name":"R0135_02340 4-phosphoerythronate dehydrogenase\tK03473 pdxB; erythronate-4-phosphate dehydrogenase [EC:1.1.1.290]" }, { "name":"R0135_06810 serC; (GenBank) 3-phosphoserine\/phosphohydroxythreonine transaminase\tK00831 serC; phosphoserine aminotransferase [EC:2.6.1.52]" }, { "name":"R0135_14490 pdxA; (GenBank) 4-hydroxythreonine-4-phosphate dehydrogenase PdxA\tK00097 pdxA; 4-hydroxythreonine-4-phosphate dehydrogenase [EC:1.1.1.262]" }, { "name":"R0135_06880 pyridoxine 5'-phosphate synthase\tK03474 pdxJ; pyridoxine 5-phosphate synthase [EC:2.6.99.2]" }, { "name":"R0135_00780 thrC; (GenBank) threonine synthase\tK01733 thrC; threonine synthase [EC:4.2.3.1]" } ] }, { "name":"00760 Nicotinate and nicotinamide metabolism [PATH:cvb00760]", "children":[ { "name":"R0135_01770 nadB; (GenBank) L-aspartate oxidase\tK00278 nadB; L-aspartate oxidase [EC:1.4.3.16]" }, { "name":"R0135_16725 nadA; (GenBank) quinolinate synthase NadA\tK03517 nadA; quinolinate synthase [EC:2.5.1.72]" }, { "name":"R0135_07105 nadC; (GenBank) carboxylating nicotinate-nucleotide diphosphorylase\tK00767 nadC; nicotinate-nucleotide pyrophosphorylase (carboxylating) [EC:2.4.2.19]" }, { "name":"R0135_02540 5'-nucleotidase\tK01081 E3.1.3.5; 5'-nucleotidase [EC:3.1.3.5]" }, { "name":"R0135_09335 nadD; (GenBank) nicotinate-nucleotide adenylyltransferase\tK00969 nadD; nicotinate-nucleotide adenylyltransferase [EC:2.7.7.18]" }, { "name":"R0135_01845 mazG; (GenBank) nucleoside triphosphate pyrophosphohydrolase\tK04765 mazG; nucleoside triphosphate diphosphatase [EC:3.6.1.9]" }, { "name":"R0135_02915 nudC; (GenBank) NAD(+) diphosphatase\tK03426 NUDT12_13; NAD+ diphosphatase [EC:3.6.1.22]" }, { "name":"R0135_17035 NAD+ synthase\tK01950 E6.3.5.1; NAD+ synthase (glutamine-hydrolysing) [EC:6.3.5.1]" }, { "name":"R0135_11630 Sir2 family NAD-dependent protein deacetylase\tK12410 cobB; NAD-dependent protein deacetylase\/lipoamidase [EC:2.3.1.286 2.3.1.313]" }, { "name":"R0135_04250 NAD(+) kinase\tK00858 ppnK; NAD+ kinase [EC:2.7.1.23]" }, { "name":"R0135_12545 Re\/Si-specific NAD(P)(+) transhydrogenase subunit alpha\tK00324 pntA; proton-translocating NAD(P)+ transhydrogenase subunit alpha [EC:7.1.1.1]" }, { "name":"R0135_12550 NAD(P) transhydrogenase subunit alpha\tK00324 pntA; proton-translocating NAD(P)+ transhydrogenase subunit alpha [EC:7.1.1.1]" }, { "name":"R0135_12555 NAD(P)(+) transhydrogenase (Re\/Si-specific) subunit beta\tK00325 pntB; proton-translocating NAD(P)+ transhydrogenase subunit beta [EC:7.1.1.1]" }, { "name":"R0135_01960 NAD-dependent succinate-semialdehyde dehydrogenase\tK00135 gabD; succinate-semialdehyde dehydrogenase \/ glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]" } ] }, { "name":"00770 Pantothenate and CoA biosynthesis [PATH:cvb00770]", "children":[ { "name":"R0135_01660 5-guanidino-2-oxopentanoate decarboxylase\tK01652 E2.2.1.6L; acetolactate synthase I\/II\/III large subunit [EC:2.2.1.6]" }, { "name":"R0135_04490 acetolactate synthase large subunit\tK01652 E2.2.1.6L; acetolactate synthase I\/II\/III large subunit [EC:2.2.1.6]" }, { "name":"R0135_04820 ilvB; (GenBank) biosynthetic-type acetolactate synthase large subunit\tK01652 E2.2.1.6L; acetolactate synthase I\/II\/III large subunit [EC:2.2.1.6]" }, { "name":"R0135_05855 acetolactate synthase large subunit\tK01652 E2.2.1.6L; acetolactate synthase I\/II\/III large subunit [EC:2.2.1.6]" }, { "name":"R0135_17065 acetolactate synthase 3 large subunit\tK01652 E2.2.1.6L; acetolactate synthase I\/II\/III large subunit [EC:2.2.1.6]" }, { "name":"R0135_17070 ilvN; (GenBank) acetolactate synthase small subunit\tK01653 E2.2.1.6S; acetolactate synthase I\/III small subunit [EC:2.2.1.6]" }, { "name":"R0135_17075 ilvC; (GenBank) ketol-acid reductoisomerase\tK00053 ilvC; ketol-acid reductoisomerase [EC:1.1.1.86]" }, { "name":"R0135_04485 ilvD; (GenBank) dihydroxy-acid dehydratase\tK01687 ilvD; dihydroxy-acid dehydratase [EC:4.2.1.9]" }, { "name":"R0135_05925 ilvD; (GenBank) dihydroxy-acid dehydratase\tK01687 ilvD; dihydroxy-acid dehydratase [EC:4.2.1.9]" }, { "name":"R0135_08220 dihydroxy-acid dehydratase\tK01687 ilvD; dihydroxy-acid dehydratase [EC:4.2.1.9]" }, { "name":"R0135_08645 panB; (GenBank) 3-methyl-2-oxobutanoate hydroxymethyltransferase\tK00606 panB; 3-methyl-2-oxobutanoate hydroxymethyltransferase [EC:2.1.2.11]" }, { "name":"R0135_04295 2-dehydropantoate 2-reductase\tK00077 panE; 2-dehydropantoate 2-reductase [EC:1.1.1.169]" }, { "name":"R0135_07080 2-dehydropantoate 2-reductase\tK00077 panE; 2-dehydropantoate 2-reductase [EC:1.1.1.169]" }, { "name":"R0135_13900 2-dehydropantoate 2-reductase\tK00077 panE; 2-dehydropantoate 2-reductase [EC:1.1.1.169]" }, { "name":"R0135_08650 panC; (GenBank) pantoate--beta-alanine ligase\tK01918 panC; pantoate--beta-alanine ligase [EC:6.3.2.1]" }, { "name":"R0135_15605 type III pantothenate kinase\tK03525 coaX; type III pantothenate kinase [EC:2.7.1.33]" }, { "name":"R0135_11470 coaBC; (GenBank) bifunctional phosphopantothenoylcysteine decarboxylase\/phosphopantothenate--cysteine ligase CoaBC\tK13038 coaBC; phosphopantothenoylcysteine decarboxylase \/ phosphopantothenate---cysteine ligase [EC:4.1.1.36 6.3.2.5]" }, { "name":"R0135_01845 mazG; (GenBank) nucleoside triphosphate pyrophosphohydrolase\tK04765 mazG; nucleoside triphosphate diphosphatase [EC:3.6.1.9]" }, { "name":"R0135_11440 coaD; (GenBank) pantetheine-phosphate adenylyltransferase\tK00954 E2.7.7.3A; pantetheine-phosphate adenylyltransferase [EC:2.7.7.3]" }, { "name":"R0135_07165 coaE; (GenBank) dephospho-CoA kinase\tK00859 coaE; dephospho-CoA kinase [EC:2.7.1.24]" }, { "name":"R0135_01830 acpS; (GenBank) holo-ACP synthase\tK00997 acpS; holo-[acyl-carrier protein] synthase [EC:2.7.8.7]" }, { "name":"R0135_16365 ACP phosphodiesterase\tK08682 acpH; acyl carrier protein phosphodiesterase [EC:3.1.4.14]" }, { "name":"R0135_08350 aminotransferase class IV\tK00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]" }, { "name":"R0135_12090 branched-chain amino acid transaminase\tK00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]" }, { "name":"R0135_06435 Zn-dependent hydrolase\tK06016 pydC; beta-ureidopropionase \/ N-carbamoyl-L-amino-acid hydrolase [EC:3.5.1.6 3.5.1.87]" }, { "name":"R0135_13385 Zn-dependent hydrolase\tK06016 pydC; beta-ureidopropionase \/ N-carbamoyl-L-amino-acid hydrolase [EC:3.5.1.6 3.5.1.87]" }, { "name":"R0135_01945 aldehyde dehydrogenase family protein\tK00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]" } ] }, { "name":"00780 Biotin metabolism [PATH:cvb00780]", "children":[ { "name":"R0135_15900 fabB; (GenBank) beta-ketoacyl-ACP synthase I\tK00647 fabB; 3-oxoacyl-[acyl-carrier-protein] synthase I [EC:2.3.1.41]" }, { "name":"R0135_03100 fabF; (GenBank) beta-ketoacyl-ACP synthase II\tK09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179]" }, { "name":"R0135_03110 fabG; (GenBank) 3-oxoacyl-ACP reductase FabG\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]" }, { "name":"R0135_04290 SDR family oxidoreductase\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]" }, { "name":"R0135_08120 SDR family oxidoreductase\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]" }, { "name":"R0135_10580 SDR family oxidoreductase\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]" }, { "name":"R0135_00080 fabZ; (GenBank) 3-hydroxyacyl-ACP dehydratase FabZ\tK02372 fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:4.2.1.59]" }, { "name":"R0135_12785 bioB; (GenBank) biotin synthase BioB\tK01012 bioB; biotin synthase [EC:2.8.1.6]" }, { "name":"R0135_15600 birA; (GenBank) bifunctional biotin--[acetyl-CoA-carboxylase] ligase\/biotin operon repressor BirA\tK03524 birA; BirA family transcriptional regulator, biotin operon repressor \/ biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]" } ] }, { "name":"00785 Lipoic acid metabolism [PATH:cvb00785]", "children":[ { "name":"R0135_09290 lipB; (GenBank) lipoyl(octanoyl) transferase LipB\tK03801 lipB; lipoyl(octanoyl) transferase [EC:2.3.1.181]" }, { "name":"R0135_04260 lipA; (GenBank) lipoyl synthase\tK03644 lipA; lipoyl synthase [EC:2.8.1.8]" }, { "name":"R0135_02270 lpdA; (GenBank) dihydrolipoyl dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]" }, { "name":"R0135_16750 aceE; (GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type\tK00163 aceE; pyruvate dehydrogenase E1 component [EC:1.2.4.1]" }, { "name":"R0135_16755 aceF; (GenBank) dihydrolipoyllysine-residue acetyltransferase\tK00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]" }, { "name":"R0135_02260 2-oxoglutarate dehydrogenase E1 component\tK00164 OGDH; 2-oxoglutarate dehydrogenase E1 component [EC:1.2.4.2]" }, { "name":"R0135_02265 odhB; (GenBank) 2-oxoglutarate dehydrogenase complex dihydrolipoyllysine-residue succinyltransferase\tK00658 DLST; 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61]" }, { "name":"R0135_00165 gcvP; (GenBank) aminomethyl-transferring glycine dehydrogenase\tK00281 GLDC; glycine cleavage system P protein (glycine dehydrogenase) [EC:1.4.4.2]" }, { "name":"R0135_12905 gcvT; (GenBank) glycine cleavage system aminomethyltransferase GcvT\tK00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]" }, { "name":"R0135_11180 gcvH; (GenBank) glycine cleavage system protein GcvH\tK02437 gcvH; glycine cleavage system H protein" } ] }, { "name":"00790 Folate biosynthesis [PATH:cvb00790]", "children":[ { "name":"R0135_02295 folE; (GenBank) GTP cyclohydrolase I FolE\tK01495 GCH1; GTP cyclohydrolase IA [EC:3.5.4.16]" }, { "name":"R0135_05480 folE; (GenBank) GTP cyclohydrolase I FolE\tK01495 GCH1; GTP cyclohydrolase IA [EC:3.5.4.16]" }, { "name":"R0135_10725 alkaline phosphatase\tK01077 ALP; alkaline phosphatase [EC:3.1.3.1]" }, { "name":"R0135_04605 alkaline phosphatase D family protein\tK01113 phoD; alkaline phosphatase D [EC:3.1.3.1]" }, { "name":"R0135_14350 folB; (GenBank) dihydroneopterin aldolase\tK01633 folB; 7,8-dihydroneopterin aldolase\/epimerase\/oxygenase [EC:4.1.2.25 5.1.99.8 1.13.11.81]" }, { "name":"R0135_08635 folK; (GenBank) 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase\tK00950 folK; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase [EC:2.7.6.3]" }, { "name":"R0135_14355 folK; (GenBank) 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase\tK00950 folK; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase [EC:2.7.6.3]" }, { "name":"R0135_08725 folP; (GenBank) dihydropteroate synthase\tK00796 folP; dihydropteroate synthase [EC:2.5.1.15]" }, { "name":"R0135_11145 dihydrofolate reductase\tK00287 DHFR; dihydrofolate reductase [EC:1.5.1.3]" }, { "name":"R0135_03850 Mur ligase family protein\tK11754 folC; dihydrofolate synthase \/ folylpolyglutamate synthase [EC:6.3.2.12 6.3.2.17]" }, { "name":"R0135_15480 ribA; (GenBank) GTP cyclohydrolase II\tK01497 ribA; GTP cyclohydrolase II [EC:3.5.4.25]" }, { "name":"R0135_04440 ribB; (GenBank) 3,4-dihydroxy-2-butanone-4-phosphate synthase\tK14652 ribBA; 3,4-dihydroxy 2-butanone 4-phosphate synthase \/ GTP cyclohydrolase II [EC:4.1.99.12 3.5.4.25]" }, { "name":"R0135_15450 ribB; (GenBank) 3,4-dihydroxy-2-butanone-4-phosphate synthase\tK14652 ribBA; 3,4-dihydroxy 2-butanone 4-phosphate synthase \/ GTP cyclohydrolase II [EC:4.1.99.12 3.5.4.25]" }, { "name":"R0135_02550 pabB; (GenBank) aminodeoxychorismate synthase component I\tK01665 pabB; para-aminobenzoate synthetase component I [EC:2.6.1.85]" }, { "name":"R0135_03095 pabC; (GenBank) aminodeoxychorismate lyase\tK02619 pabC; 4-amino-4-deoxychorismate lyase [EC:4.1.3.38]" }, { "name":"R0135_04385 queD; (GenBank) 6-carboxytetrahydropterin synthase QueD\tK01737 queD; 6-pyruvoyltetrahydropterin\/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50]" }, { "name":"R0135_17465 6-carboxytetrahydropterin synthase\tK01737 queD; 6-pyruvoyltetrahydropterin\/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50]" }, { "name":"R0135_10555 4a-hydroxytetrahydrobiopterin dehydratase\tK01724 PCBD; 4a-hydroxytetrahydrobiopterin dehydratase [EC:4.2.1.96]" }, { "name":"R0135_15995 aromatic amino acid hydroxylase\tK00500 phhA; phenylalanine-4-hydroxylase [EC:1.14.16.1]" }, { "name":"R0135_09170 queE; (GenBank) 7-carboxy-7-deazaguanine synthase QueE\tK10026 queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3]" }, { "name":"R0135_09165 queC; (GenBank) 7-cyano-7-deazaguanine synthase QueC\tK06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20]" }, { "name":"R0135_02370 queF; (GenBank) NADPH-dependent 7-cyano-7-deazaguanine reductase QueF\tK06879 queF; 7-cyano-7-deazaguanine reductase [EC:1.7.1.13]" }, { "name":"R0135_09545 moaA; (GenBank) GTP 3',8-cyclase MoaA\tK03639 moaA; GTP 3',8-cyclase [EC:4.1.99.22]" }, { "name":"R0135_02495 moaC; (GenBank) cyclic pyranopterin monophosphate synthase MoaC\tK03637 moaC; cyclic pyranopterin monophosphate synthase [EC:4.6.1.17]" }, { "name":"R0135_02505 molybdenum cofactor biosynthesis protein MoaE\tK03635 MOCS2B; molybdopterin synthase catalytic subunit [EC:2.8.1.12]" }, { "name":"R0135_15890 moaB; (GenBank) molybdenum cofactor biosynthesis protein B\tK03638 moaB; molybdopterin adenylyltransferase [EC:2.7.7.75]" }, { "name":"R0135_15895 molybdopterin molybdotransferase MoeA\tK03750 moeA; molybdopterin molybdotransferase [EC:2.10.1.1]" }, { "name":"R0135_15970 nucleotidyltransferase family protein\tK07141 mocA; molybdenum cofactor cytidylyltransferase [EC:2.7.7.76]" }, { "name":"R0135_01855 molybdenum cofactor guanylyltransferase\tK03752 mobA; molybdenum cofactor guanylyltransferase [EC:2.7.7.77]" } ] }, { "name":"00670 One carbon pool by folate [PATH:cvb00670]", "children":[ { "name":"R0135_11145 dihydrofolate reductase\tK00287 DHFR; dihydrofolate reductase [EC:1.5.1.3]" }, { "name":"R0135_04840 folD; (GenBank) bifunctional methylenetetrahydrofolate dehydrogenase\/methenyltetrahydrofolate cyclohydrolase FolD\tK01491 folD; methylenetetrahydrofolate dehydrogenase (NADP+) \/ methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9]" }, { "name":"R0135_15430 glyA; (GenBank) serine hydroxymethyltransferase\tK00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]" }, { "name":"R0135_17415 purN; (GenBank) phosphoribosylglycinamide formyltransferase\tK11175 purN; phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2]" }, { "name":"R0135_14560 purH; (GenBank) bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase\/IMP cyclohydrolase\tK00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase \/ IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]" }, { "name":"R0135_12905 gcvT; (GenBank) glycine cleavage system aminomethyltransferase GcvT\tK00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]" }, { "name":"R0135_02980 metH; (GenBank) methionine synthase\tK00548 metH; 5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]" }, { "name":"R0135_11150 thymidylate synthase\tK00560 thyA; thymidylate synthase [EC:2.1.1.45]" }, { "name":"R0135_04845 purU; (GenBank) formyltetrahydrofolate deformylase\tK01433 purU; formyltetrahydrofolate deformylase [EC:3.5.1.10]" }, { "name":"R0135_11325 metF; (GenBank) methylenetetrahydrofolate reductase [NAD(P)H]\tK00297 metF; methylenetetrahydrofolate reductase (NADH) [EC:1.5.1.54]" }, { "name":"R0135_11220 5-formyltetrahydrofolate cyclo-ligase\tK01934 MTHFS; 5-formyltetrahydrofolate cyclo-ligase [EC:6.3.3.2]" }, { "name":"R0135_11315 metK; (GenBank) methionine adenosyltransferase\tK00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6]" }, { "name":"R0135_11320 ahcY; (GenBank) adenosylhomocysteinase\tK01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1]" }, { "name":"R0135_00165 gcvP; (GenBank) aminomethyl-transferring glycine dehydrogenase\tK00281 GLDC; glycine cleavage system P protein (glycine dehydrogenase) [EC:1.4.4.2]" }, { "name":"R0135_02270 lpdA; (GenBank) dihydrolipoyl dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]" }, { "name":"R0135_11180 gcvH; (GenBank) glycine cleavage system protein GcvH\tK02437 gcvH; glycine cleavage system H protein" }, { "name":"R0135_04995 betA; (GenBank) choline dehydrogenase\tK00108 betA; choline dehydrogenase [EC:1.1.99.1]" }, { "name":"R0135_04990 betB; (GenBank) betaine-aldehyde dehydrogenase\tK00130 betB; betaine-aldehyde dehydrogenase [EC:1.2.1.8]" } ] }, { "name":"00830 Retinol metabolism" }, { "name":"00860 Porphyrin metabolism [PATH:cvb00860]", "children":[ { "name":"R0135_04595 gltX; (GenBank) glutamate--tRNA ligase\tK01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]" }, { "name":"R0135_07520 hemA; (GenBank) glutamyl-tRNA reductase\tK02492 hemA; glutamyl-tRNA reductase [EC:1.2.1.70]" }, { "name":"R0135_14650 hemL; (GenBank) glutamate-1-semialdehyde 2,1-aminomutase\tK01845 hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8]" }, { "name":"R0135_14645 hemB; (GenBank) porphobilinogen synthase\tK01698 hemB; porphobilinogen synthase [EC:4.2.1.24]" }, { "name":"R0135_09650 hemC; (GenBank) hydroxymethylbilane synthase\tK01749 hemC; hydroxymethylbilane synthase [EC:2.5.1.61]" }, { "name":"R0135_09645 uroporphyrinogen-III synthase\tK01719 hemD; uroporphyrinogen-III synthase [EC:4.2.1.75]" }, { "name":"R0135_12740 hemE; (GenBank) uroporphyrinogen decarboxylase\tK01599 hemE; uroporphyrinogen decarboxylase [EC:4.1.1.37]" }, { "name":"R0135_11925 hemF; (GenBank) oxygen-dependent coproporphyrinogen oxidase\tK00228 CPOX; coproporphyrinogen III oxidase [EC:1.3.3.3]" }, { "name":"R0135_01740 hemN; (GenBank) oxygen-independent coproporphyrinogen III oxidase\tK02495 hemN; oxygen-independent coproporphyrinogen III oxidase [EC:1.3.98.3]" }, { "name":"R0135_17240 radical SAM protein\tK02495 hemN; oxygen-independent coproporphyrinogen III oxidase [EC:1.3.98.3]" }, { "name":"R0135_14655 CopD family protein\tK08973 hemJ; protoporphyrinogen IX oxidase [EC:1.3.99.-]" }, { "name":"R0135_15955 hemH; (GenBank) ferrochelatase\tK01772 hemH; protoporphyrin\/coproporphyrin ferrochelatase [EC:4.98.1.1 4.99.1.9]" }, { "name":"R0135_09640 uroporphyrinogen-III C-methyltransferase\tK02496 hemX; uroporphyrin-III C-methyltransferase [EC:2.1.1.107]" }, { "name":"R0135_02685 cysG; (GenBank) siroheme synthase CysG\tK02302 cysG; uroporphyrin-III C-methyltransferase \/ precorrin-2 dehydrogenase \/ sirohydrochlorin ferrochelatase [EC:2.1.1.107 1.3.1.76 4.99.1.4]" }, { "name":"R0135_11985 cyoE; (GenBank) heme o synthase\tK02257 COX10; heme o synthase [EC:2.5.1.141]" }, { "name":"R0135_08310 COX15\/CtaA family protein\tK02259 COX15; heme a synthase [EC:1.17.99.9]" }, { "name":"R0135_01350 cobO; (GenBank) cob(I)yrinic acid a,c-diamide adenosyltransferase\tK19221 cobA; cob(I)alamin adenosyltransferase [EC:2.5.1.17]" }, { "name":"R0135_17280 magnesium chelatase subunit H\tK03403 chlH; magnesium chelatase subunit H [EC:6.6.1.1]" }, { "name":"R0135_17150 magnesium chelatase subunit D\tK03404 chlD; magnesium chelatase subunit D [EC:6.6.1.1]" }, { "name":"R0135_17145 bchI; (GenBank) magnesium chelatase ATPase subunit I\tK03405 chlI; magnesium chelatase subunit I [EC:6.6.1.1]" }, { "name":"R0135_17270 bchM; (GenBank) magnesium protoporphyrin IX methyltransferase\tK03428 bchM; magnesium-protoporphyrin O-methyltransferase [EC:2.1.1.11]" }, { "name":"R0135_17325 acsF; (GenBank) magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase\tK04035 E1.14.13.81; magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase [EC:1.14.13.81]" }, { "name":"R0135_01935 NAD(P)H-binding protein\tK19073 DVR; divinyl chlorophyllide a 8-vinyl-reductase [EC:1.3.1.75]" }, { "name":"R0135_17135 bchJ; (GenBank) bacteriochlorophyll 4-vinyl reductase\tK04036 bchJ; divinyl protochlorophyllide a 8-vinyl-reductase [EC:1.-.-.-]" }, { "name":"R0135_17275 bchL; (GenBank) ferredoxin:protochlorophyllide reductase (ATP-dependent) iron-sulfur ATP-binding protein\tK04037 chlL; light-independent protochlorophyllide reductase subunit L [EC:1.3.7.7]" }, { "name":"R0135_17290 ferredoxin:protochlorophyllide reductase (ATP-dependent) subunit N\tK04038 chlN; light-independent protochlorophyllide reductase subunit N [EC:1.3.7.7]" }, { "name":"R0135_17285 bchB; (GenBank) ferredoxin:protochlorophyllide reductase (ATP-dependent) subunit B\tK04039 chlB; light-independent protochlorophyllide reductase subunit B [EC:1.3.7.7]" }, { "name":"R0135_17305 chlG; (GenBank) chlorophyll synthase ChlG\tK04040 chlG; chlorophyll\/bacteriochlorophyll a synthase [EC:2.5.1.62 2.5.1.133]" }, { "name":"R0135_17190 chlorophyllide a reductase iron protein subunit X\tK11333 bchX; 3,8-divinyl chlorophyllide a\/chlorophyllide a reductase subunit X [EC:1.3.7.14 1.3.7.15]" }, { "name":"R0135_17195 bchY; (GenBank) chlorophyllide a reductase subunit Y\tK11334 bchY; 3,8-divinyl chlorophyllide a\/chlorophyllide a reductase subunit Y [EC:1.3.7.14 1.3.7.15]" }, { "name":"R0135_17200 bchZ; (GenBank) chlorophyllide a reductase subunit Z\tK11335 bchZ; 3,8-divinyl chlorophyllide a\/chlorophyllide a reductase subunit Z [EC:1.3.7.14 1.3.7.15]" }, { "name":"R0135_17295 bchF; (GenBank) 2-vinyl bacteriochlorophyllide hydratase\tK11336 bchF; 3-vinyl bacteriochlorophyllide hydratase [EC:4.2.1.165]" }, { "name":"R0135_17185 bchC; (GenBank) chlorophyll synthesis pathway protein BchC\tK11337 bchC; bacteriochlorophyllide a dehydrogenase [EC:1.1.1.396]" }, { "name":"R0135_17315 geranylgeranyl diphosphate reductase\tK10960 chlP; geranylgeranyl diphosphate\/geranylgeranyl-bacteriochlorophyllide a reductase [EC:1.3.1.83 1.3.1.111]" }, { "name":"R0135_09350 bfr; (GenBank) bacterioferritin\tK03594 bfr; bacterioferritin [EC:1.16.3.1]" } ] }, { "name":"00130 Ubiquinone and other terpenoid-quinone biosynthesis [PATH:cvb00130]", "children":[ { "name":"R0135_09205 ybgC; (GenBank) tol-pal system-associated acyl-CoA thioesterase\tK01075 E3.1.2.23; 4-hydroxybenzoyl-CoA thioesterase [EC:3.1.2.23]" }, { "name":"R0135_11550 chorismate lyase\tK03181 ubiC; chorismate lyase [EC:4.1.3.40]" }, { "name":"R0135_11555 ubiA; (GenBank) 4-hydroxybenzoate octaprenyltransferase\tK03179 ubiA; 4-hydroxybenzoate polyprenyltransferase [EC:2.5.1.39]" }, { "name":"R0135_09630 ubiD; (GenBank) 4-hydroxy-3-polyprenylbenzoate decarboxylase\tK03182 ubiD; 4-hydroxy-3-polyprenylbenzoate decarboxylase [EC:4.1.1.98]" }, { "name":"R0135_10995 UbiX family flavin prenyltransferase\tK03186 ubiX; flavin prenyltransferase [EC:2.5.1.129]" }, { "name":"R0135_11185 UbiH\/UbiF\/VisC\/COQ6 family ubiquinone biosynthesis hydroxylase\tK18800 ubiI; 2-polyprenylphenol 6-hydroxylase [EC:1.14.13.240]" }, { "name":"R0135_06825 ubiG; (GenBank) bifunctional 2-polyprenyl-6-hydroxyphenol methylase\/3-demethylubiquinol 3-O-methyltransferase UbiG\tK00568 ubiG; 2-polyprenyl-6-hydroxyphenyl methylase \/ 3-demethylubiquinone-9 3-methyltransferase [EC:2.1.1.222 2.1.1.64]" }, { "name":"R0135_11190 ubiH; (GenBank) 2-octaprenyl-6-methoxyphenyl hydroxylase\tK03185 ubiH; 2-octaprenyl-6-methoxyphenol hydroxylase [EC:1.14.13.-]" }, { "name":"R0135_12630 ubiE; (GenBank) bifunctional demethylmenaquinone methyltransferase\/2-methoxy-6-polyprenyl-1,4-benzoquinol methylase UbiE\tK03183 ubiE; demethylmenaquinone methyltransferase \/ 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase [EC:2.1.1.163 2.1.1.201]" }, { "name":"R0135_14550 coq7; (GenBank) 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinone monooxygenase\tK06134 coq7; 3-demethoxyubiquinol 3-hydroxylase [EC:1.14.99.60]" }, { "name":"R0135_04575 prenyltransferase\tK02548 menA; 1,4-dihydroxy-2-naphthoate polyprenyltransferase [EC:2.5.1.74]" }, { "name":"R0135_14070 prenyltransferase\tK02548 menA; 1,4-dihydroxy-2-naphthoate polyprenyltransferase [EC:2.5.1.74]" }, { "name":"R0135_17485 wrbA; (GenBank) NAD(P)H:quinone oxidoreductase\tK03809 wrbA; NAD(P)H dehydrogenase (quinone) [EC:1.6.5.2]" }, { "name":"R0135_04800 hppD; (GenBank) 4-hydroxyphenylpyruvate dioxygenase\tK00457 HPD; 4-hydroxyphenylpyruvate dioxygenase [EC:1.13.11.27]" } ] } ] }, { "name":"09109 Metabolism of terpenoids and polyketides", "children":[ { "name":"00900 Terpenoid backbone biosynthesis [PATH:cvb00900]", "children":[ { "name":"R0135_15510 dxs; (GenBank) 1-deoxy-D-xylulose-5-phosphate synthase\tK01662 dxs; 1-deoxy-D-xylulose-5-phosphate synthase [EC:2.2.1.7]" }, { "name":"R0135_00055 ispC; (GenBank) 1-deoxy-D-xylulose-5-phosphate reductoisomerase\tK00099 dxr; 1-deoxy-D-xylulose-5-phosphate reductoisomerase [EC:1.1.1.267]" }, { "name":"R0135_05380 ispD; (GenBank) 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase\tK00991 ispD; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [EC:2.7.7.60]" }, { "name":"R0135_07545 ispE; (GenBank) 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase\tK00919 ispE; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [EC:2.7.1.148]" }, { "name":"R0135_05375 ispF; (GenBank) 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase\tK01770 ispF; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [EC:4.6.1.12]" }, { "name":"R0135_00980 ispG; (GenBank) flavodoxin-dependent (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase\tK03526 gcpE; (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase [EC:1.17.7.1 1.17.7.3]" }, { "name":"R0135_16995 ispH; (GenBank) 4-hydroxy-3-methylbut-2-enyl diphosphate reductase\tK03527 ispH; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase [EC:1.17.7.4]" }, { "name":"R0135_00330 acetyl-CoA C-acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" }, { "name":"R0135_03970 acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" }, { "name":"R0135_04435 acetyl-CoA C-acyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" }, { "name":"R0135_05075 acetyl-CoA C-acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" }, { "name":"R0135_11080 acetyl-CoA C-acyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" }, { "name":"R0135_11085 acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" }, { "name":"R0135_10995 UbiX family flavin prenyltransferase\tK03186 ubiX; flavin prenyltransferase [EC:2.5.1.129]" }, { "name":"R0135_17235 idi; (GenBank) isopentenyl-diphosphate Delta-isomerase\tK01823 idi; isopentenyl-diphosphate Delta-isomerase [EC:5.3.3.2]" }, { "name":"R0135_15485 polyprenyl synthetase family protein\tK00795 ispA; farnesyl diphosphate synthase [EC:2.5.1.1 2.5.1.10]" }, { "name":"R0135_17175 polyprenyl synthetase family protein\tK13789 GGPS; geranylgeranyl diphosphate synthase, type II [EC:2.5.1.1 2.5.1.10 2.5.1.29]" }, { "name":"R0135_15925 polyprenyl synthetase family protein\tK02523 ispB; octaprenyl-diphosphate synthase [EC:2.5.1.90]" }, { "name":"R0135_00045 uppS; (GenBank) polyprenyl diphosphate synthase\tK00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31]" }, { "name":"R0135_17315 geranylgeranyl diphosphate reductase\tK10960 chlP; geranylgeranyl diphosphate\/geranylgeranyl-bacteriochlorophyllide a reductase [EC:1.3.1.83 1.3.1.111]" }, { "name":"R0135_04765 hydroxymethylglutaryl-CoA reductase\tK28139 fcrA; alcohol-forming fatty acyl-CoA reductase [EC:1.2.1.84]" }, { "name":"R0135_08785 acetyl-CoA C-acyltransferase\tK00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16]" } ] }, { "name":"00902 Monoterpenoid biosynthesis" }, { "name":"00909 Sesquiterpenoid and triterpenoid biosynthesis" }, { "name":"00904 Diterpenoid biosynthesis" }, { "name":"00906 Carotenoid biosynthesis [PATH:cvb00906]", "children":[ { "name":"R0135_17165 phytoene\/squalene synthase family protein\tK02291 crtB; 15-cis-phytoene synthase [EC:2.5.1.32]" }, { "name":"R0135_17160 phytoene desaturase\tK10027 crtI; phytoene desaturase [EC:1.3.99.26 1.3.99.28 1.3.99.29 1.3.99.31]" }, { "name":"R0135_17170 carotenoid 1,2-hydratase\tK09844 crtC; carotenoid 1,2-hydratase [EC:4.2.1.131]" }, { "name":"R0135_08835 crtI; (GenBank) phytoene desaturase family protein\tK09845 crtD; 1-hydroxycarotenoid 3,4-desaturase [EC:1.3.99.27]" }, { "name":"R0135_17180 methyltransferase\tK09846 crtF; demethylspheroidene O-methyltransferase [EC:2.1.1.210]" } ] }, { "name":"00905 Brassinosteroid biosynthesis" }, { "name":"00981 Insect hormone biosynthesis" }, { "name":"00908 Zeatin biosynthesis" }, { "name":"00903 Limonene degradation", "children":[ { "name":"R0135_01945 aldehyde dehydrogenase family protein\tK00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]" } ] }, { "name":"00907 Pinene, camphor and geraniol degradation [PATH:cvb00907]", "children":[ { "name":"R0135_09395 fadB; (GenBank) fatty acid oxidation complex subunit alpha FadB\tK01825 fadB; 3-hydroxyacyl-CoA dehydrogenase \/ enoyl-CoA hydratase \/ 3-hydroxybutyryl-CoA epimerase \/ enoyl-CoA isomerase [EC:1.1.1.35 4.2.1.17 5.1.2.3 5.3.3.8]" }, { "name":"R0135_00335 3-hydroxyacyl-CoA dehydrogenase NAD-binding domain-containing protein\tK01782 fadJ; 3-hydroxyacyl-CoA dehydrogenase \/ enoyl-CoA hydratase \/ 3-hydroxybutyryl-CoA epimerase [EC:1.1.1.35 4.2.1.17 5.1.2.3]" }, { "name":"R0135_12345 NAD(P)-dependent oxidoreductase\tK13775 atuG; citronellol\/citronellal dehydrogenase" }, { "name":"R0135_10030 acetyl-CoA carboxylase biotin carboxylase subunit\tK13777 atuF; geranyl-CoA carboxylase alpha subunit [EC:6.4.1.5]" }, { "name":"R0135_10040 acyl-CoA carboxylase subunit beta\tK13778 atuC; geranyl-CoA carboxylase beta subunit [EC:6.4.1.5]" }, { "name":"R0135_10035 enoyl-CoA hydratase-related protein\tK13779 atuE; isohexenylglutaconyl-CoA hydratase [EC:4.2.1.57]" }, { "name":"R0135_00130 hydroxymethylglutaryl-CoA lyase\tK01640 HMGCL; hydroxymethylglutaryl-CoA lyase [EC:4.1.3.4]" }, { "name":"R0135_15570 hydroxymethylglutaryl-CoA lyase\tK01640 HMGCL; hydroxymethylglutaryl-CoA lyase [EC:4.1.3.4]" }, { "name":"R0135_08785 acetyl-CoA C-acyltransferase\tK00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16]" }, { "name":"R0135_09400 fadA; (GenBank) acetyl-CoA C-acyltransferase FadA\tK00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16]" } ] }, { "name":"01052 Type I polyketide structures" }, { "name":"00522 Biosynthesis of 12-, 14- and 16-membered macrolides" }, { "name":"01051 Biosynthesis of ansamycins", "children":[ { "name":"R0135_11305 tkt; (GenBank) transketolase\tK00615 E2.2.1.1; transketolase [EC:2.2.1.1]" } ] }, { "name":"01059 Biosynthesis of enediyne antibiotics" }, { "name":"01056 Biosynthesis of type II polyketide backbone" }, { "name":"01057 Biosynthesis of type II polyketide products" }, { "name":"00253 Tetracycline biosynthesis" }, { "name":"00523 Polyketide sugar unit biosynthesis [PATH:cvb00523]", "children":[ { "name":"R0135_12120 rfbA; (GenBank) glucose-1-phosphate thymidylyltransferase RfbA\tK00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]" }, { "name":"R0135_12105 rfbB; (GenBank) dTDP-glucose 4,6-dehydratase\tK01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]" }, { "name":"R0135_12115 rfbC; (GenBank) dTDP-4-dehydrorhamnose 3,5-epimerase\tK01790 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase [EC:5.1.3.13]" }, { "name":"R0135_12100 rfbD; (GenBank) dTDP-4-dehydrorhamnose reductase\tK00067 rfbD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133]" }, { "name":"R0135_15885 sugar nucleotide-binding protein\tK00067 rfbD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133]" } ] }, { "name":"01054 Nonribosomal peptide structures [PATH:cvb01054]", "children":[ { "name":"R0135_04080 amino acid racemase\tK01779 racD; aspartate racemase [EC:5.1.1.13]" } ] }, { "name":"01053 Biosynthesis of siderophore group nonribosomal peptides" }, { "name":"01055 Biosynthesis of vancomycin group antibiotics", "children":[ { "name":"R0135_12105 rfbB; (GenBank) dTDP-glucose 4,6-dehydratase\tK01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]" } ] } ] }, { "name":"09110 Biosynthesis of other secondary metabolites", "children":[ { "name":"00940 Phenylpropanoid biosynthesis" }, { "name":"00945 Stilbenoid, diarylheptanoid and gingerol biosynthesis" }, { "name":"00941 Flavonoid biosynthesis" }, { "name":"00944 Flavone and flavonol biosynthesis" }, { "name":"00942 Anthocyanin biosynthesis" }, { "name":"00943 Isoflavonoid biosynthesis" }, { "name":"00946 Degradation of flavonoids [PATH:cvb00946]", "children":[ { "name":"R0135_05190 bglX; (GenBank) beta-glucosidase BglX\tK05349 bglX; beta-glucosidase [EC:3.2.1.21]" }, { "name":"R0135_05195 glycoside hydrolase family 3 protein\tK05349 bglX; beta-glucosidase [EC:3.2.1.21]" }, { "name":"R0135_13810 glycoside hydrolase family 3 N-terminal domain-containing protein\tK05349 bglX; beta-glucosidase [EC:3.2.1.21]" } ] }, { "name":"00901 Indole alkaloid biosynthesis" }, { "name":"00403 Indole diterpene alkaloid biosynthesis" }, { "name":"00950 Isoquinoline alkaloid biosynthesis" }, { "name":"00960 Tropane, piperidine and pyridine alkaloid biosynthesis" }, { "name":"00996 Biosynthesis of various alkaloids" }, { "name":"00232 Caffeine metabolism" }, { "name":"00965 Betalain biosynthesis" }, { "name":"00966 Glucosinolate biosynthesis" }, { "name":"00402 Benzoxazinoid biosynthesis" }, { "name":"00311 Penicillin and cephalosporin biosynthesis" }, { "name":"00332 Carbapenem biosynthesis [PATH:cvb00332]", "children":[ { "name":"R0135_13670 proB; (GenBank) glutamate 5-kinase\tK00931 proB; glutamate 5-kinase [EC:2.7.2.11]" }, { "name":"R0135_15945 proB; (GenBank) glutamate 5-kinase\tK00931 proB; glutamate 5-kinase [EC:2.7.2.11]" }, { "name":"R0135_09340 glutamate-5-semialdehyde dehydrogenase\tK00147 proA; glutamate-5-semialdehyde dehydrogenase [EC:1.2.1.41]" }, { "name":"R0135_13660 glutamate-5-semialdehyde dehydrogenase\tK00147 proA; glutamate-5-semialdehyde dehydrogenase [EC:1.2.1.41]" } ] }, { "name":"00261 Monobactam biosynthesis [PATH:cvb00261]", "children":[ { "name":"R0135_07045 sat; (GenBank) sulfate adenylyltransferase\tK00958 sat; sulfate adenylyltransferase [EC:2.7.7.4]" }, { "name":"R0135_00205 aspartate kinase\tK00928 lysC; aspartate kinase [EC:2.7.2.4]" }, { "name":"R0135_03885 aspartate-semialdehyde dehydrogenase\tK00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]" }, { "name":"R0135_17530 dapA; (GenBank) 4-hydroxy-tetrahydrodipicolinate synthase\tK01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7]" }, { "name":"R0135_16640 dapB; (GenBank) 4-hydroxy-tetrahydrodipicolinate reductase\tK00215 dapB; 4-hydroxy-tetrahydrodipicolinate reductase [EC:1.17.1.8]" } ] }, { "name":"00331 Clavulanic acid biosynthesis" }, { "name":"00521 Streptomycin biosynthesis [PATH:cvb00521]", "children":[ { "name":"R0135_05150 glk; (GenBank) glucokinase\tK00845 glk; glucokinase [EC:2.7.1.2]" }, { "name":"R0135_11475 phosphomannomutase\/phosphoglucomutase\tK15778 pmm-pgm; phosphomannomutase \/ phosphoglucomutase [EC:5.4.2.8 5.4.2.2]" }, { "name":"R0135_00950 inositol monophosphatase family protein\tK01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25]" }, { "name":"R0135_02860 inositol monophosphatase family protein\tK01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25]" }, { "name":"R0135_12120 rfbA; (GenBank) glucose-1-phosphate thymidylyltransferase RfbA\tK00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]" }, { "name":"R0135_12105 rfbB; (GenBank) dTDP-glucose 4,6-dehydratase\tK01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]" }, { "name":"R0135_12115 rfbC; (GenBank) dTDP-4-dehydrorhamnose 3,5-epimerase\tK01790 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase [EC:5.1.3.13]" }, { "name":"R0135_12100 rfbD; (GenBank) dTDP-4-dehydrorhamnose reductase\tK00067 rfbD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133]" }, { "name":"R0135_15885 sugar nucleotide-binding protein\tK00067 rfbD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133]" } ] }, { "name":"00524 Neomycin, kanamycin and gentamicin biosynthesis", "children":[ { "name":"R0135_05150 glk; (GenBank) glucokinase\tK00845 glk; glucokinase [EC:2.7.1.2]" } ] }, { "name":"00525 Acarbose and validamycin biosynthesis [PATH:cvb00525]", "children":[ { "name":"R0135_12120 rfbA; (GenBank) glucose-1-phosphate thymidylyltransferase RfbA\tK00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]" }, { "name":"R0135_12105 rfbB; (GenBank) dTDP-glucose 4,6-dehydratase\tK01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]" } ] }, { "name":"00401 Novobiocin biosynthesis [PATH:cvb00401]", "children":[ { "name":"R0135_08335 amino acid aminotransferase\tK00813 aspC; aspartate aminotransferase [EC:2.6.1.1]" }, { "name":"R0135_02225 hisC; (GenBank) histidinol-phosphate transaminase\tK00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]" }, { "name":"R0135_03320 histidinol-phosphate transaminase\tK00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]" } ] }, { "name":"00404 Staurosporine biosynthesis", "children":[ { "name":"R0135_05740 tryptophan halogenase family protein\tK14266 prnA; tryptophan 7-halogenase [EC:1.14.19.9]" }, { "name":"R0135_05755 tryptophan halogenase family protein\tK14266 prnA; tryptophan 7-halogenase [EC:1.14.19.9]" } ] }, { "name":"00405 Phenazine biosynthesis", "children":[ { "name":"R0135_14520 trpE; (GenBank) anthranilate synthase component I\tK01657 trpE; anthranilate synthase component I [EC:4.1.3.27]" }, { "name":"R0135_14525 aminodeoxychorismate\/anthranilate synthase component II\tK01658 trpG; anthranilate synthase component II [EC:4.1.3.27]" } ] }, { "name":"00333 Prodigiosin biosynthesis", "children":[ { "name":"R0135_03115 fabD; (GenBank) ACP S-malonyltransferase\tK00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]" }, { "name":"R0135_03110 fabG; (GenBank) 3-oxoacyl-ACP reductase FabG\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]" }, { "name":"R0135_04290 SDR family oxidoreductase\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]" }, { "name":"R0135_08120 SDR family oxidoreductase\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]" }, { "name":"R0135_10580 SDR family oxidoreductase\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]" } ] }, { "name":"00254 Aflatoxin biosynthesis" }, { "name":"00975 Biosynthesis of various siderophores" }, { "name":"00998 Biosynthesis of various antibiotics", "children":[ { "name":"R0135_03105 acpP; (GenBank) acyl carrier protein\tK02078 acpP; acyl carrier protein" } ] }, { "name":"00999 Biosynthesis of various plant secondary metabolites [PATH:cvb00999]", "children":[ { "name":"R0135_11315 metK; (GenBank) methionine adenosyltransferase\tK00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6]" }, { "name":"R0135_11930 aroE; (GenBank) shikimate dehydrogenase\tK00014 aroE; shikimate dehydrogenase [EC:1.1.1.25]" }, { "name":"R0135_05190 bglX; (GenBank) beta-glucosidase BglX\tK05349 bglX; beta-glucosidase [EC:3.2.1.21]" }, { "name":"R0135_05195 glycoside hydrolase family 3 protein\tK05349 bglX; beta-glucosidase [EC:3.2.1.21]" }, { "name":"R0135_13810 glycoside hydrolase family 3 N-terminal domain-containing protein\tK05349 bglX; beta-glucosidase [EC:3.2.1.21]" } ] }, { "name":"00997 Biosynthesis of various other secondary metabolites" } ] }, { "name":"09111 Xenobiotics biodegradation and metabolism", "children":[ { "name":"00362 Benzoate degradation [PATH:cvb00362]", "children":[ { "name":"R0135_08785 acetyl-CoA C-acyltransferase\tK00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16]" }, { "name":"R0135_09400 fadA; (GenBank) acetyl-CoA C-acyltransferase FadA\tK00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16]" }, { "name":"R0135_10625 hypothetical protein\tK02554 mhpD; 2-keto-4-pentenoate hydratase [EC:4.2.1.80]" }, { "name":"R0135_16415 iron-containing alcohol dehydrogenase\tK00217 E1.3.1.32; maleylacetate reductase [EC:1.3.1.32]" }, { "name":"R0135_13540 2Fe-2S iron-sulfur cluster-binding protein\tK04755 fdx; ferredoxin, 2Fe-2S" }, { "name":"R0135_09205 ybgC; (GenBank) tol-pal system-associated acyl-CoA thioesterase\tK01075 E3.1.2.23; 4-hydroxybenzoyl-CoA thioesterase [EC:3.1.2.23]" }, { "name":"R0135_16650 acyl-CoA dehydrogenase family protein\tK04118 pimC; pimeloyl-CoA dehydrogenase large subunit [EC:1.3.1.62]" }, { "name":"R0135_16655 acyl-CoA dehydrogenase\tK28556 pimD; pimeloyl-CoA dehydrogenase small subunit [EC:1.3.1.62]" }, { "name":"R0135_00335 3-hydroxyacyl-CoA dehydrogenase NAD-binding domain-containing protein\tK01782 fadJ; 3-hydroxyacyl-CoA dehydrogenase \/ enoyl-CoA hydratase \/ 3-hydroxybutyryl-CoA epimerase [EC:1.1.1.35 4.2.1.17 5.1.2.3]" }, { "name":"R0135_09395 fadB; (GenBank) fatty acid oxidation complex subunit alpha FadB\tK01825 fadB; 3-hydroxyacyl-CoA dehydrogenase \/ enoyl-CoA hydratase \/ 3-hydroxybutyryl-CoA epimerase \/ enoyl-CoA isomerase [EC:1.1.1.35 4.2.1.17 5.1.2.3 5.3.3.8]" }, { "name":"R0135_05415 sodium ion-translocating decarboxylase subunit beta\tK20509 madB; carboxybiotin decarboxylase [EC:7.2.4.1]" }, { "name":"R0135_10745 acyl-CoA dehydrogenase\tK00252 GCDH; glutaryl-CoA dehydrogenase [EC:1.3.8.6]" }, { "name":"R0135_09105 3-hydroxyacyl-CoA dehydrogenase NAD-binding domain-containing protein\tK00074 paaH; 3-hydroxybutyryl-CoA dehydrogenase [EC:1.1.1.157]" }, { "name":"R0135_00330 acetyl-CoA C-acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" }, { "name":"R0135_03970 acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" }, { "name":"R0135_04435 acetyl-CoA C-acyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" }, { "name":"R0135_05075 acetyl-CoA C-acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" }, { "name":"R0135_11080 acetyl-CoA C-acyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" }, { "name":"R0135_11085 acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" } ] }, { "name":"00627 Aminobenzoate degradation [PATH:cvb00627]", "children":[ { "name":"R0135_08555 NAD(P)\/FAD-dependent oxidoreductase\tK10215 ethA; monooxygenase [EC:1.14.13.-]" }, { "name":"R0135_00450 amidase family protein\tK01426 E3.5.1.4; amidase [EC:3.5.1.4]" }, { "name":"R0135_01070 amidase\tK01426 E3.5.1.4; amidase [EC:3.5.1.4]" }, { "name":"R0135_06570 amidase family protein\tK01426 E3.5.1.4; amidase [EC:3.5.1.4]" }, { "name":"R0135_08295 amidase\tK01426 E3.5.1.4; amidase [EC:3.5.1.4]" }, { "name":"R0135_13905 amidase family protein\tK01426 E3.5.1.4; amidase [EC:3.5.1.4]" }, { "name":"R0135_04505 carbon-nitrogen hydrolase family protein\tK01501 E3.5.5.1; nitrilase [EC:3.5.5.1]" }, { "name":"R0135_10995 UbiX family flavin prenyltransferase\tK03186 ubiX; flavin prenyltransferase [EC:2.5.1.129]" } ] }, { "name":"00364 Fluorobenzoate degradation", "children":[ { "name":"R0135_16415 iron-containing alcohol dehydrogenase\tK00217 E1.3.1.32; maleylacetate reductase [EC:1.3.1.32]" } ] }, { "name":"00625 Chloroalkane and chloroalkene degradation [PATH:cvb00625]", "children":[ { "name":"R0135_04870 haloalkane dehalogenase\tK01563 dhaA; haloalkane dehalogenase [EC:3.8.1.5]" }, { "name":"R0135_08885 haloalkane dehalogenase\tK01563 dhaA; haloalkane dehalogenase [EC:3.8.1.5]" }, { "name":"R0135_00320 S-(hydroxymethyl)glutathione dehydrogenase\/class III alcohol dehydrogenase\tK00121 frmA; S-(hydroxymethyl)glutathione dehydrogenase \/ alcohol dehydrogenase [EC:1.1.1.284 1.1.1.1]" }, { "name":"R0135_01945 aldehyde dehydrogenase family protein\tK00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]" }, { "name":"R0135_09475 molybdopterin-dependent oxidoreductase\tK20625 ahy; acetylene hydratase [EC:4.2.1.112]" } ] }, { "name":"00361 Chlorocyclohexane and chlorobenzene degradation [PATH:cvb00361]", "children":[ { "name":"R0135_04870 haloalkane dehalogenase\tK01563 dhaA; haloalkane dehalogenase [EC:3.8.1.5]" }, { "name":"R0135_08885 haloalkane dehalogenase\tK01563 dhaA; haloalkane dehalogenase [EC:3.8.1.5]" }, { "name":"R0135_16415 iron-containing alcohol dehydrogenase\tK00217 E1.3.1.32; maleylacetate reductase [EC:1.3.1.32]" } ] }, { "name":"00623 Toluene degradation [PATH:cvb00623]", "children":[ { "name":"R0135_16415 iron-containing alcohol dehydrogenase\tK00217 E1.3.1.32; maleylacetate reductase [EC:1.3.1.32]" } ] }, { "name":"00622 Xylene degradation", "children":[ { "name":"R0135_10625 hypothetical protein\tK02554 mhpD; 2-keto-4-pentenoate hydratase [EC:4.2.1.80]" } ] }, { "name":"00633 Nitrotoluene degradation" }, { "name":"00642 Ethylbenzene degradation", "children":[ { "name":"R0135_08785 acetyl-CoA C-acyltransferase\tK00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16]" }, { "name":"R0135_09400 fadA; (GenBank) acetyl-CoA C-acyltransferase FadA\tK00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16]" } ] }, { "name":"00643 Styrene degradation [PATH:cvb00643]", "children":[ { "name":"R0135_15985 homogentisate 1,2-dioxygenase\tK00451 HGD; homogentisate 1,2-dioxygenase [EC:1.13.11.5]" }, { "name":"R0135_15975 maiA; (GenBank) maleylacetoacetate isomerase\tK01800 maiA; maleylacetoacetate isomerase [EC:5.2.1.2]" }, { "name":"R0135_15980 fumarylacetoacetate hydrolase family protein\tK16171 faaH; fumarylacetoacetate (FAA) hydrolase [EC:3.7.1.2]" }, { "name":"R0135_00450 amidase family protein\tK01426 E3.5.1.4; amidase [EC:3.5.1.4]" }, { "name":"R0135_01070 amidase\tK01426 E3.5.1.4; amidase [EC:3.5.1.4]" }, { "name":"R0135_06570 amidase family protein\tK01426 E3.5.1.4; amidase [EC:3.5.1.4]" }, { "name":"R0135_08295 amidase\tK01426 E3.5.1.4; amidase [EC:3.5.1.4]" }, { "name":"R0135_13905 amidase family protein\tK01426 E3.5.1.4; amidase [EC:3.5.1.4]" }, { "name":"R0135_04505 carbon-nitrogen hydrolase family protein\tK01501 E3.5.5.1; nitrilase [EC:3.5.5.1]" } ] }, { "name":"00791 Atrazine degradation", "children":[ { "name":"R0135_02770 ureC; (GenBank) urease subunit alpha\tK01428 ureC; urease subunit alpha [EC:3.5.1.5]" }, { "name":"R0135_02775 urease subunit beta\tK01429 ureB; urease subunit beta [EC:3.5.1.5]" }, { "name":"R0135_02780 ureA; (GenBank) urease subunit gamma\tK01430 ureA; urease subunit gamma [EC:3.5.1.5]" } ] }, { "name":"00930 Caprolactam degradation [PATH:cvb00930]", "children":[ { "name":"R0135_00225 SMP-30\/gluconolactonase\/LRE family protein\tK01053 gnl; gluconolactonase [EC:3.1.1.17]" }, { "name":"R0135_09395 fadB; (GenBank) fatty acid oxidation complex subunit alpha FadB\tK01825 fadB; 3-hydroxyacyl-CoA dehydrogenase \/ enoyl-CoA hydratase \/ 3-hydroxybutyryl-CoA epimerase \/ enoyl-CoA isomerase [EC:1.1.1.35 4.2.1.17 5.1.2.3 5.3.3.8]" }, { "name":"R0135_00335 3-hydroxyacyl-CoA dehydrogenase NAD-binding domain-containing protein\tK01782 fadJ; 3-hydroxyacyl-CoA dehydrogenase \/ enoyl-CoA hydratase \/ 3-hydroxybutyryl-CoA epimerase [EC:1.1.1.35 4.2.1.17 5.1.2.3]" } ] }, { "name":"00363 Bisphenol degradation" }, { "name":"00621 Dioxin degradation", "children":[ { "name":"R0135_10625 hypothetical protein\tK02554 mhpD; 2-keto-4-pentenoate hydratase [EC:4.2.1.80]" } ] }, { "name":"00626 Naphthalene degradation [PATH:cvb00626]", "children":[ { "name":"R0135_00320 S-(hydroxymethyl)glutathione dehydrogenase\/class III alcohol dehydrogenase\tK00121 frmA; S-(hydroxymethyl)glutathione dehydrogenase \/ alcohol dehydrogenase [EC:1.1.1.284 1.1.1.1]" } ] }, { "name":"00624 Polycyclic aromatic hydrocarbon degradation" }, { "name":"00365 Furfural degradation" }, { "name":"00984 Steroid degradation [PATH:cvb00984]", "children":[ { "name":"R0135_01565 CaiB\/BaiF CoA-transferase family protein\tK01796 AMACR; alpha-methylacyl-CoA racemase [EC:5.1.99.4]" }, { "name":"R0135_08785 acetyl-CoA C-acyltransferase\tK00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16]" }, { "name":"R0135_09400 fadA; (GenBank) acetyl-CoA C-acyltransferase FadA\tK00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16]" } ] }, { "name":"00980 Metabolism of xenobiotics by cytochrome P450" }, { "name":"00982 Drug metabolism - cytochrome P450" }, { "name":"00983 Drug metabolism - other enzymes" } ] }, { "name":"09112 Not included in regular maps", "children":[ { "name":"09113 Global maps only" } ] } ] }, { "name":"09120 Genetic Information Processing", "children":[ { "name":"09121 Transcription", "children":[ { "name":"03020 RNA polymerase [PATH:cvb03020]", "children":[ { "name":"R0135_15680 rpoB; (GenBank) DNA-directed RNA polymerase subunit beta\tK03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]" }, { "name":"R0135_15685 rpoC; (GenBank) DNA-directed RNA polymerase subunit beta'\tK03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]" }, { "name":"R0135_15860 rpoA; (GenBank) DNA-directed RNA polymerase subunit alpha\tK03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]" }, { "name":"R0135_11520 rpoZ; (GenBank) DNA-directed RNA polymerase subunit omega\tK03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]" } ] }, { "name":"03022 Basal transcription factors" }, { "name":"03040 Spliceosome" } ] }, { "name":"09122 Translation", "children":[ { "name":"03010 Ribosome [PATH:cvb03010]", "children":[ { "name":"R0135_14690 16S ribosomal RNA\tK01977 16SrRNA; 16S ribosomal RNA" }, { "name":"R0135_17090 16S ribosomal RNA\tK01977 16SrRNA; 16S ribosomal RNA" }, { "name":"R0135_14710 rrf; (GenBank) 5S ribosomal RNA\tK01985 5SrRNA; 5S ribosomal RNA" }, { "name":"R0135_17110 rrf; (GenBank) 5S ribosomal RNA\tK01985 5SrRNA; 5S ribosomal RNA" }, { "name":"R0135_06785 rpsA; (GenBank) 30S ribosomal protein S1\tK02945 RP-S1; small subunit ribosomal protein S1" }, { "name":"R0135_00025 rpsB; (GenBank) 30S ribosomal protein S2\tK02967 RP-S2; small subunit ribosomal protein S2" }, { "name":"R0135_15765 rpsC; (GenBank) 30S ribosomal protein S3\tK02982 RP-S3; small subunit ribosomal protein S3" }, { "name":"R0135_15855 rpsD; (GenBank) 30S ribosomal protein S4\tK02986 RP-S4; small subunit ribosomal protein S4" }, { "name":"R0135_15820 rpsE; (GenBank) 30S ribosomal protein S5\tK02988 RP-S5; small subunit ribosomal protein S5" }, { "name":"R0135_15370 rpsF; (GenBank) 30S ribosomal protein S6\tK02990 RP-S6; small subunit ribosomal protein S6" }, { "name":"R0135_15700 rpsG; (GenBank) 30S ribosomal protein S7\tK02992 RP-S7; small subunit ribosomal protein S7" }, { "name":"R0135_15805 rpsH; (GenBank) 30S ribosomal protein S8\tK02994 RP-S8; small subunit ribosomal protein S8" }, { "name":"R0135_07315 rpsI; (GenBank) 30S ribosomal protein S9\tK02996 RP-S9; small subunit ribosomal protein S9" }, { "name":"R0135_15730 rpsJ; (GenBank) 30S ribosomal protein S10\tK02946 RP-S10; small subunit ribosomal protein S10" }, { "name":"R0135_15850 rpsK; (GenBank) 30S ribosomal protein S11\tK02948 RP-S11; small subunit ribosomal protein S11" }, { "name":"R0135_15695 rpsL; (GenBank) 30S ribosomal protein S12\tK02950 RP-S12; small subunit ribosomal protein S12" }, { "name":"R0135_15845 rpsM; (GenBank) 30S ribosomal protein S13\tK02952 RP-S13; small subunit ribosomal protein S13" }, { "name":"R0135_15800 rpsN; (GenBank) 30S ribosomal protein S14\tK02954 RP-S14; small subunit ribosomal protein S14" }, { "name":"R0135_08670 rpsO; (GenBank) 30S ribosomal protein S15\tK02956 RP-S15; small subunit ribosomal protein S15" }, { "name":"R0135_00740 rpsP; (GenBank) 30S ribosomal protein S16\tK02959 RP-S16; small subunit ribosomal protein S16" }, { "name":"R0135_15780 rpsQ; (GenBank) 30S ribosomal protein S17\tK02961 RP-S17; small subunit ribosomal protein S17" }, { "name":"R0135_15375 rpsR; (GenBank) 30S ribosomal protein S18\tK02963 RP-S18; small subunit ribosomal protein S18" }, { "name":"R0135_15755 rpsS; (GenBank) 30S ribosomal protein S19\tK02965 RP-S19; small subunit ribosomal protein S19" }, { "name":"R0135_09445 rpsT; (GenBank) 30S ribosomal protein S20\tK02968 RP-S20; small subunit ribosomal protein S20" }, { "name":"R0135_14340 rpsU; (GenBank) 30S ribosomal protein S21\tK02970 RP-S21; small subunit ribosomal protein S21" }, { "name":"R0135_15665 rplA; (GenBank) 50S ribosomal protein L1\tK02863 RP-L1; large subunit ribosomal protein L1" }, { "name":"R0135_15750 rplB; (GenBank) 50S ribosomal protein L2\tK02886 RP-L2; large subunit ribosomal protein L2" }, { "name":"R0135_15735 rplC; (GenBank) 50S ribosomal protein L3\tK02906 RP-L3; large subunit ribosomal protein L3" }, { "name":"R0135_15740 rplD; (GenBank) 50S ribosomal protein L4\tK02926 RP-L4; large subunit ribosomal protein L4" }, { "name":"R0135_15795 rplE; (GenBank) 50S ribosomal protein L5\tK02931 RP-L5; large subunit ribosomal protein L5" }, { "name":"R0135_15810 rplF; (GenBank) 50S ribosomal protein L6\tK02933 RP-L6; large subunit ribosomal protein L6" }, { "name":"R0135_15385 rplI; (GenBank) 50S ribosomal protein L9\tK02939 RP-L9; large subunit ribosomal protein L9" }, { "name":"R0135_15670 rplJ; (GenBank) 50S ribosomal protein L10\tK02864 RP-L10; large subunit ribosomal protein L10" }, { "name":"R0135_15660 rplK; (GenBank) 50S ribosomal protein L11\tK02867 RP-L11; large subunit ribosomal protein L11" }, { "name":"R0135_15675 rplL; (GenBank) 50S ribosomal protein L7\/L12\tK02935 RP-L7; large subunit ribosomal protein L7\/L12" }, { "name":"R0135_07320 rplM; (GenBank) 50S ribosomal protein L13\tK02871 RP-L13; large subunit ribosomal protein L13" }, { "name":"R0135_15785 rplN; (GenBank) 50S ribosomal protein L14\tK02874 RP-L14; large subunit ribosomal protein L14" }, { "name":"R0135_15830 rplO; (GenBank) 50S ribosomal protein L15\tK02876 RP-L15; large subunit ribosomal protein L15" }, { "name":"R0135_15770 rplP; (GenBank) 50S ribosomal protein L16\tK02878 RP-L16; large subunit ribosomal protein L16" }, { "name":"R0135_15865 rplQ; (GenBank) 50S ribosomal protein L17\tK02879 RP-L17; large subunit ribosomal protein L17" }, { "name":"R0135_15815 rplR; (GenBank) 50S ribosomal protein L18\tK02881 RP-L18; large subunit ribosomal protein L18" }, { "name":"R0135_00755 rplS; (GenBank) 50S ribosomal protein L19\tK02884 RP-L19; large subunit ribosomal protein L19" }, { "name":"R0135_06080 rplT; (GenBank) 50S ribosomal protein L20\tK02887 RP-L20; large subunit ribosomal protein L20" }, { "name":"R0135_15930 rplU; (GenBank) 50S ribosomal protein L21\tK02888 RP-L21; large subunit ribosomal protein L21" }, { "name":"R0135_15760 rplV; (GenBank) 50S ribosomal protein L22\tK02890 RP-L22; large subunit ribosomal protein L22" }, { "name":"R0135_15745 rplW; (GenBank) 50S ribosomal protein L23\tK02892 RP-L23; large subunit ribosomal protein L23" }, { "name":"R0135_15790 rplX; (GenBank) 50S ribosomal protein L24\tK02895 RP-L24; large subunit ribosomal protein L24" }, { "name":"R0135_07560 50S ribosomal protein L25\/general stress protein Ctc\tK02897 RP-L25; large subunit ribosomal protein L25" }, { "name":"R0135_15935 rpmA; (GenBank) 50S ribosomal protein L27\tK02899 RP-L27; large subunit ribosomal protein L27" }, { "name":"R0135_11460 rpmB; (GenBank) 50S ribosomal protein L28\tK02902 RP-L28; large subunit ribosomal protein L28" }, { "name":"R0135_15775 rpmC; (GenBank) 50S ribosomal protein L29\tK02904 RP-L29; large subunit ribosomal protein L29" }, { "name":"R0135_15825 rpmD; (GenBank) 50S ribosomal protein L30\tK02907 RP-L30; large subunit ribosomal protein L30" }, { "name":"R0135_12665 rpmE; (GenBank) 50S ribosomal protein L31\tK02909 RP-L31; large subunit ribosomal protein L31" }, { "name":"R0135_03120 rpmF; (GenBank) 50S ribosomal protein L32\tK02911 RP-L32; large subunit ribosomal protein L32" }, { "name":"R0135_11455 rpmG; (GenBank) 50S ribosomal protein L33\tK02913 RP-L33; large subunit ribosomal protein L33" }, { "name":"R0135_11740 rpmH; (GenBank) 50S ribosomal protein L34\tK02914 RP-L34; large subunit ribosomal protein L34" }, { "name":"R0135_06085 rpmI; (GenBank) 50S ribosomal protein L35\tK02916 RP-L35; large subunit ribosomal protein L35" }, { "name":"R0135_15840 rpmJ; (GenBank) 50S ribosomal protein L36\tK02919 RP-L36; large subunit ribosomal protein L36" } ] }, { "name":"00970 Aminoacyl-tRNA biosynthesis [PATH:cvb00970]", "children":[ { "name":"R0135_04570 tRNA-Ala\tK14218 tRNA-Ala; tRNA Ala" }, { "name":"R0135_14700 tRNA-Ala\tK14218 tRNA-Ala; tRNA Ala" }, { "name":"R0135_17100 tRNA-Ala\tK14218 tRNA-Ala; tRNA Ala" }, { "name":"R0135_03625 tRNA-Arg\tK14219 tRNA-Arg; tRNA Arg" }, { "name":"R0135_04125 tRNA-Arg\tK14219 tRNA-Arg; tRNA Arg" }, { "name":"R0135_05965 tRNA-Arg\tK14219 tRNA-Arg; tRNA Arg" }, { "name":"R0135_13505 tRNA-Arg\tK14219 tRNA-Arg; tRNA Arg" }, { "name":"R0135_06110 tRNA-Asn\tK14220 tRNA-Asn; tRNA Asn" }, { "name":"R0135_04375 tRNA-Asp\tK14221 tRNA-Asp; tRNA Asp" }, { "name":"R0135_03380 tRNA-Cys\tK14222 tRNA-Cys; tRNA Cys" }, { "name":"R0135_07550 tRNA-Gln\tK14223 tRNA-Gln; tRNA Gln" }, { "name":"R0135_02350 tRNA-Glu\tK14224 tRNA-Glu; tRNA Glu" }, { "name":"R0135_02345 tRNA-Gly\tK14225 tRNA-Gly; tRNA Gly" }, { "name":"R0135_03385 tRNA-Gly\tK14225 tRNA-Gly; tRNA Gly" }, { "name":"R0135_13260 tRNA-Gly\tK14225 tRNA-Gly; tRNA Gly" }, { "name":"R0135_15630 tRNA-Gly\tK14225 tRNA-Gly; tRNA Gly" }, { "name":"R0135_03630 tRNA-His\tK14226 tRNA-His; tRNA His" }, { "name":"R0135_14695 tRNA-Ile\tK14227 tRNA-Ile; tRNA Ile" }, { "name":"R0135_17095 tRNA-Ile\tK14227 tRNA-Ile; tRNA Ile" }, { "name":"R0135_00695 tRNA-Leu\tK14228 tRNA-Leu; tRNA Leu" }, { "name":"R0135_03065 tRNA-Leu\tK14228 tRNA-Leu; tRNA Leu" }, { "name":"R0135_03240 tRNA-Leu\tK14228 tRNA-Leu; tRNA Leu" }, { "name":"R0135_08705 tRNA-Leu\tK14228 tRNA-Leu; tRNA Leu" }, { "name":"R0135_15355 tRNA-Leu\tK14228 tRNA-Leu; tRNA Leu" }, { "name":"R0135_09150 tRNA-Lys\tK14229 tRNA-Lys; tRNA Lys" }, { "name":"R0135_08235 tRNA-Met\tK14230 tRNA-Met; tRNA Met" }, { "name":"R0135_08700 tRNA-Met\tK14230 tRNA-Met; tRNA Met" }, { "name":"R0135_14300 tRNA-Ile\tK14230 tRNA-Met; tRNA Met" }, { "name":"R0135_12335 tRNA-Phe\tK14231 tRNA-Phe; tRNA Phe" }, { "name":"R0135_03635 tRNA-Pro\tK14232 tRNA-Pro; tRNA Pro" }, { "name":"R0135_06055 tRNA-Pro\tK14232 tRNA-Pro; tRNA Pro" }, { "name":"R0135_12800 tRNA-Pro\tK14232 tRNA-Pro; tRNA Pro" }, { "name":"R0135_00220 tRNA-Ser\tK14233 tRNA-Ser; tRNA Ser" }, { "name":"R0135_02385 tRNA-Ser\tK14233 tRNA-Ser; tRNA Ser" }, { "name":"R0135_03175 tRNA-Ser\tK14233 tRNA-Ser; tRNA Ser" }, { "name":"R0135_15615 tRNA-Thr\tK14234 tRNA-Thr; tRNA Thr" }, { "name":"R0135_15635 tRNA-Thr\tK14234 tRNA-Thr; tRNA Thr" }, { "name":"R0135_15645 tRNA-Trp\tK14235 tRNA-Trp; tRNA Trp" }, { "name":"R0135_15625 tRNA-Tyr\tK14236 tRNA-Tyr; tRNA Tyr" }, { "name":"R0135_04380 tRNA-Val\tK14237 tRNA-Val; tRNA Val" }, { "name":"R0135_10675 tRNA-Val\tK14237 tRNA-Val; tRNA Val" }, { "name":"R0135_04595 gltX; (GenBank) glutamate--tRNA ligase\tK01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]" }, { "name":"R0135_07470 gatA; (GenBank) Asp-tRNA(Asn)\/Glu-tRNA(Gln) amidotransferase subunit GatA\tK02433 gatA; aspartyl-tRNA(Asn)\/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7]" }, { "name":"R0135_07475 gatB; (GenBank) Asp-tRNA(Asn)\/Glu-tRNA(Gln) amidotransferase subunit GatB\tK02434 gatB; aspartyl-tRNA(Asn)\/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7]" }, { "name":"R0135_07465 gatC; (GenBank) Asp-tRNA(Asn)\/Glu-tRNA(Gln) amidotransferase subunit GatC\tK02435 gatC; aspartyl-tRNA(Asn)\/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7]" }, { "name":"R0135_03645 glutamine--tRNA ligase\/YqeY domain fusion protein\tK01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18]" }, { "name":"R0135_00200 alaS; (GenBank) alanine--tRNA ligase\tK01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]" }, { "name":"R0135_09230 aspS; (GenBank) aspartate--tRNA ligase\tK01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]" }, { "name":"R0135_14910 asnS; (GenBank) asparagine--tRNA ligase\tK01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]" }, { "name":"R0135_11835 glyQ; (GenBank) glycine--tRNA ligase subunit alpha\tK01878 glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14]" }, { "name":"R0135_11830 glyS; (GenBank) glycine--tRNA ligase subunit beta\tK01879 glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14]" }, { "name":"R0135_06095 thrS; (GenBank) threonine--tRNA ligase\tK01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]" }, { "name":"R0135_02680 serS; (GenBank) serine--tRNA ligase\tK01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]" }, { "name":"R0135_03640 cysS; (GenBank) cysteine--tRNA ligase\tK01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]" }, { "name":"R0135_17395 metG; (GenBank) methionine--tRNA ligase\tK01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]" }, { "name":"R0135_11900 fmt; (GenBank) methionyl-tRNA formyltransferase\tK00604 MTFMT; methionyl-tRNA formyltransferase [EC:2.1.2.9]" }, { "name":"R0135_01615 valine--tRNA ligase\tK01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]" }, { "name":"R0135_08400 leuS; (GenBank) leucine--tRNA ligase\tK01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]" }, { "name":"R0135_16980 ileS; (GenBank) isoleucine--tRNA ligase\tK01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]" }, { "name":"R0135_00795 lysS; (GenBank) lysine--tRNA ligase\tK04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]" }, { "name":"R0135_12655 argS; (GenBank) arginine--tRNA ligase\tK01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]" }, { "name":"R0135_09245 proline--tRNA ligase\tK01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]" }, { "name":"R0135_00985 hisS; (GenBank) histidine--tRNA ligase\tK01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]" }, { "name":"R0135_06075 pheS; (GenBank) phenylalanine--tRNA ligase subunit alpha\tK01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]" }, { "name":"R0135_06070 pheT; (GenBank) phenylalanine--tRNA ligase subunit beta\tK01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]" }, { "name":"R0135_14685 tyrS; (GenBank) tyrosine--tRNA ligase\tK01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]" }, { "name":"R0135_01880 trpS; (GenBank) tryptophan--tRNA ligase\tK01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]" } ] }, { "name":"03013 Nucleocytoplasmic transport" }, { "name":"03015 mRNA surveillance pathway" }, { "name":"03008 Ribosome biogenesis in eukaryotes [PATH:cvb03008]", "children":[ { "name":"R0135_01815 rnc; (GenBank) ribonuclease III\tK03685 rnc; ribonuclease III [EC:3.1.26.3]" }, { "name":"R0135_14935 orn; (GenBank) oligoribonuclease\tK13288 orn; oligoribonuclease [EC:3.1.-.-]" }, { "name":"R0135_16485 PA4780 family RIO1-like protein kinase\tK07178 RIOK1; RIO kinase 1 [EC:2.7.11.1]" } ] } ] }, { "name":"09123 Folding, sorting and degradation", "children":[ { "name":"03060 Protein export [PATH:cvb03060]", "children":[ { "name":"R0135_15835 secY; (GenBank) preprotein translocase subunit SecY\tK03076 secY; preprotein translocase subunit SecY" }, { "name":"R0135_15650 secE; (GenBank) preprotein translocase subunit SecE\tK03073 secE; preprotein translocase subunit SecE" }, { "name":"R0135_08710 secG; (GenBank) preprotein translocase subunit SecG\tK03075 secG; preprotein translocase subunit SecG" }, { "name":"R0135_00940 secD; (GenBank) protein translocase subunit SecD\tK03072 secD; preprotein translocase subunit SecD" }, { "name":"R0135_00945 secF; (GenBank) protein translocase subunit SecF\tK03074 secF; preprotein translocase subunit SecF" }, { "name":"R0135_02530 yajC; (GenBank) preprotein translocase subunit YajC\tK03210 yajC; preprotein translocase subunit YajC" }, { "name":"R0135_11725 yidC; (GenBank) membrane protein insertase YidC\tK03217 yidC; YidC\/Oxa1 family membrane protein insertase" }, { "name":"R0135_07180 secA; (GenBank) preprotein translocase subunit SecA\tK03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]" }, { "name":"R0135_12410 secB; (GenBank) protein-export chaperone SecB\tK03071 secB; preprotein translocase subunit SecB" }, { "name":"R0135_00735 ffh; (GenBank) signal recognition particle protein\tK03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]" }, { "name":"R0135_03600 ffs; (GenBank) signal recognition particle sRNA small type\tK01983 ffs; signal recognition particle 4.5S RNA" }, { "name":"R0135_11430 ftsY; (GenBank) signal recognition particle-docking protein FtsY\tK03110 ftsY; fused signal recognition particle receptor" }, { "name":"R0135_12605 tatA; (GenBank) twin-arginine translocase TatA\/TatE family subunit\tK03116 tatA; sec-independent protein translocase protein TatA" }, { "name":"R0135_12600 tatB; (GenBank) Sec-independent protein translocase protein TatB\tK03117 tatB; sec-independent protein translocase protein TatB" }, { "name":"R0135_12595 tatC; (GenBank) twin-arginine translocase subunit TatC\tK03118 tatC; sec-independent protein translocase protein TatC" }, { "name":"R0135_01805 lepB; (GenBank) signal peptidase I\tK03100 lepB; signal peptidase I [EC:3.4.21.89]" }, { "name":"R0135_16985 lspA; (GenBank) signal peptidase II\tK03101 lspA; signal peptidase II [EC:3.4.23.36]" } ] }, { "name":"04141 Protein processing in endoplasmic reticulum [PATH:cvb04141]", "children":[ { "name":"R0135_02285 htpG; (GenBank) molecular chaperone HtpG\tK04079 HSP90A; molecular chaperone HtpG" }, { "name":"R0135_15195 Hsp20\/alpha crystallin family protein\tK13993 HSP20; HSP20 family protein" } ] }, { "name":"04130 SNARE interactions in vesicular transport" }, { "name":"04120 Ubiquitin mediated proteolysis" }, { "name":"04122 Sulfur relay system [PATH:cvb04122]", "children":[ { "name":"R0135_00960 IscS subfamily cysteine desulfurase\tK04487 iscS; cysteine desulfurase [EC:2.8.1.7]" }, { "name":"R0135_06890 sulfurtransferase\tK01011 TST; thiosulfate\/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2]" }, { "name":"R0135_02330 tusA; (GenBank) sulfurtransferase TusA\tK04085 tusA; tRNA 2-thiouridine synthesizing protein A [EC:2.8.1.-]" }, { "name":"R0135_16735 sulfurtransferase TusA family protein\tK04085 tusA; tRNA 2-thiouridine synthesizing protein A [EC:2.8.1.-]" }, { "name":"R0135_03215 DsrH\/TusB family sulfur metabolism protein\tK07237 tusB; tRNA 2-thiouridine synthesizing protein B" }, { "name":"R0135_03210 DsrE family protein\tK07236 tusC; tRNA 2-thiouridine synthesizing protein C" }, { "name":"R0135_03205 tusD; (GenBank) sulfurtransferase complex subunit TusD\tK07235 tusD; tRNA 2-thiouridine synthesizing protein D [EC:2.8.1.-]" }, { "name":"R0135_03220 TusE\/DsrC\/DsvC family sulfur relay protein\tK11179 tusE; tRNA 2-thiouridine synthesizing protein E [EC:2.8.1.-]" }, { "name":"R0135_02615 mnmA; (GenBank) tRNA 2-thiouridine(34) synthase MnmA\tK00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13]" }, { "name":"R0135_02505 molybdenum cofactor biosynthesis protein MoaE\tK03635 MOCS2B; molybdopterin synthase catalytic subunit [EC:2.8.1.12]" }, { "name":"R0135_09545 moaA; (GenBank) GTP 3',8-cyclase MoaA\tK03639 moaA; GTP 3',8-cyclase [EC:4.1.99.22]" }, { "name":"R0135_02500 MoaD\/ThiS family protein\tK03636 moaD; sulfur-carrier protein" }, { "name":"R0135_07505 HesA\/MoeB\/ThiF family protein\tK21029 moeB; molybdopterin-synthase adenylyltransferase [EC:2.7.7.80]" }, { "name":"R0135_02495 moaC; (GenBank) cyclic pyranopterin monophosphate synthase MoaC\tK03637 moaC; cyclic pyranopterin monophosphate synthase [EC:4.6.1.17]" }, { "name":"R0135_15890 moaB; (GenBank) molybdenum cofactor biosynthesis protein B\tK03638 moaB; molybdopterin adenylyltransferase [EC:2.7.7.75]" } ] }, { "name":"03050 Proteasome" }, { "name":"03018 RNA degradation [PATH:cvb03018]", "children":[ { "name":"R0135_11170 RNA pyrophosphohydrolase\tK08311 nudH; putative (di)nucleoside polyphosphate hydrolase [EC:3.6.1.-]" }, { "name":"R0135_03140 rne; (GenBank) ribonuclease E\tK08300 rne; ribonuclease E [EC:3.1.26.12]" }, { "name":"R0135_07495 rhlB; (GenBank) ATP-dependent RNA helicase RhlB\tK03732 rhlB; ATP-dependent RNA helicase RhlB [EC:5.6.2.7]" }, { "name":"R0135_05390 eno; (GenBank) phosphopyruvate hydratase\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]" }, { "name":"R0135_08665 pnp; (GenBank) polyribonucleotide nucleotidyltransferase\tK00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]" }, { "name":"R0135_00315 DEAD\/DEAH box helicase\tK11927 rhlE; ATP-dependent RNA helicase RhlE [EC:5.6.2.7]" }, { "name":"R0135_06625 DEAD\/DEAH box helicase\tK11927 rhlE; ATP-dependent RNA helicase RhlE [EC:5.6.2.7]" }, { "name":"R0135_15360 rnr; (GenBank) ribonuclease R\tK12573 rnr; ribonuclease R [EC:3.1.13.1]" }, { "name":"R0135_16490 DEAD\/DEAH box helicase\tK05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7]" }, { "name":"R0135_06680 recQ; (GenBank) DNA helicase RecQ\tK03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]" }, { "name":"R0135_09625 rho; (GenBank) transcription termination factor Rho\tK03628 rho; transcription termination factor Rho" }, { "name":"R0135_10840 ribonuclease J\tK12574 rnj; ribonuclease J [EC:3.1.-.-]" }, { "name":"R0135_16630 dnaK; (GenBank) molecular chaperone DnaK\tK04043 dnaK; molecular chaperone DnaK" }, { "name":"R0135_16930 groL; (GenBank) chaperonin GroEL\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]" }, { "name":"R0135_14970 hfq; (GenBank) RNA chaperone Hfq\tK03666 hfq; host factor-I protein" }, { "name":"R0135_02020 ppk1; (GenBank) polyphosphate kinase 1\tK00937 ppk1; polyphosphate kinase [EC:2.7.4.1]" }, { "name":"R0135_00525 ppk2; (GenBank) polyphosphate kinase 2\tK22468 ppk2; polyphosphate kinase [EC:2.7.4.34]" }, { "name":"R0135_13270 ppk2; (GenBank) polyphosphate kinase 2\tK22468 ppk2; polyphosphate kinase [EC:2.7.4.34]" }, { "name":"R0135_08630 pcnB; (GenBank) polynucleotide adenylyltransferase PcnB\tK00970 pcnB; poly(A) polymerase [EC:2.7.7.19]" } ] } ] }, { "name":"09124 Replication and repair", "children":[ { "name":"03030 DNA replication [PATH:cvb03030]", "children":[ { "name":"R0135_01445 3'-5' exonuclease\tK02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]" }, { "name":"R0135_02925 dnaQ; (GenBank) DNA polymerase III subunit epsilon\tK02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]" }, { "name":"R0135_00100 dnaE; (GenBank) DNA polymerase III subunit alpha\tK02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]" }, { "name":"R0135_03595 dnaX; (GenBank) DNA polymerase III subunit gamma\/tau\tK02343 dnaX; DNA polymerase III subunit gamma\/tau [EC:2.7.7.7]" }, { "name":"R0135_03080 DNA polymerase III subunit delta'\tK02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]" }, { "name":"R0135_08410 holA; (GenBank) DNA polymerase III subunit delta\tK02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]" }, { "name":"R0135_01620 DNA polymerase III subunit chi\tK02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7]" }, { "name":"R0135_11750 dnaN; (GenBank) DNA polymerase III subunit beta\tK02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]" }, { "name":"R0135_15390 dnaB; (GenBank) replicative DNA helicase\tK02314 dnaB; replicative DNA helicase [EC:5.6.2.3]" }, { "name":"R0135_14330 dnaG; (GenBank) DNA primase\tK02316 dnaG; DNA primase [EC:2.7.7.101]" }, { "name":"R0135_15880 ssb; (GenBank) single-stranded DNA-binding protein\tK03111 ssb; single-strand DNA-binding protein" }, { "name":"R0135_02930 rnhA; (GenBank) ribonuclease HI\tK03469 rnhA; ribonuclease HI [EC:3.1.26.4]" }, { "name":"R0135_00095 rnhB; (GenBank) ribonuclease HII\tK03470 rnhB; ribonuclease HII [EC:3.1.26.4]" }, { "name":"R0135_11995 polA; (GenBank) DNA polymerase I\tK02335 polA; DNA polymerase I [EC:2.7.7.7]" }, { "name":"R0135_02180 ligA; (GenBank) NAD-dependent DNA ligase LigA\tK01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]" } ] }, { "name":"03410 Base excision repair [PATH:cvb03410]", "children":[ { "name":"R0135_00005 nth; (GenBank) endonuclease III\tK10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]" }, { "name":"R0135_01750 ung; (GenBank) uracil-DNA glycosylase\tK03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]" }, { "name":"R0135_12355 mutY; (GenBank) A\/G-specific adenine glycosylase\tK03575 mutY; A\/G-specific adenine glycosylase [EC:3.2.2.31]" }, { "name":"R0135_14170 hypothetical protein\tK03575 mutY; A\/G-specific adenine glycosylase [EC:3.2.2.31]" }, { "name":"R0135_11450 mutM; (GenBank) bifunctional DNA-formamidopyrimidine glycosylase\/DNA-(apurinic or apyrimidinic site) lyase\tK10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]" }, { "name":"R0135_10845 nei; (GenBank) endonuclease VIII\tK05522 nei; endonuclease VIII [EC:3.2.2.- 4.2.99.18]" }, { "name":"R0135_09860 DNA-3-methyladenine glycosylase 2 family protein\tK01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]" }, { "name":"R0135_16690 DNA-3-methyladenine glycosylase I\tK01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]" }, { "name":"R0135_02525 exodeoxyribonuclease III\tK01142 xthA; exodeoxyribonuclease III [EC:3.1.11.2]" }, { "name":"R0135_11500 exodeoxyribonuclease III\tK01142 xthA; exodeoxyribonuclease III [EC:3.1.11.2]" }, { "name":"R0135_15155 nfo; (GenBank) deoxyribonuclease IV\tK01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]" }, { "name":"R0135_11995 polA; (GenBank) DNA polymerase I\tK02335 polA; DNA polymerase I [EC:2.7.7.7]" }, { "name":"R0135_00785 recJ; (GenBank) single-stranded-DNA-specific exonuclease RecJ\tK07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]" }, { "name":"R0135_02180 ligA; (GenBank) NAD-dependent DNA ligase LigA\tK01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]" } ] }, { "name":"03420 Nucleotide excision repair [PATH:cvb03420]", "children":[ { "name":"R0135_03495 mfd; (GenBank) transcription-repair coupling factor\tK03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]" }, { "name":"R0135_15870 uvrA; (GenBank) excinuclease ABC subunit UvrA\tK03701 uvrA; excinuclease ABC subunit A" }, { "name":"R0135_06105 uvrB; (GenBank) excinuclease ABC subunit UvrB\tK03702 uvrB; excinuclease ABC subunit B" }, { "name":"R0135_03395 uvrC; (GenBank) excinuclease ABC subunit UvrC\tK03703 uvrC; excinuclease ABC subunit C" }, { "name":"R0135_11605 uvrD; (GenBank) DNA helicase II\tK03657 uvrD; ATP-dependent DNA helicase UvrD\/PcrA [EC:5.6.2.4]" }, { "name":"R0135_11995 polA; (GenBank) DNA polymerase I\tK02335 polA; DNA polymerase I [EC:2.7.7.7]" }, { "name":"R0135_02180 ligA; (GenBank) NAD-dependent DNA ligase LigA\tK01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]" } ] }, { "name":"03430 Mismatch repair [PATH:cvb03430]", "children":[ { "name":"R0135_05345 mutS; (GenBank) DNA mismatch repair protein MutS\tK03555 mutS; DNA mismatch repair protein MutS" }, { "name":"R0135_14960 mutL; (GenBank) DNA mismatch repair endonuclease MutL\tK03572 mutL; DNA mismatch repair protein MutL" }, { "name":"R0135_11605 uvrD; (GenBank) DNA helicase II\tK03657 uvrD; ATP-dependent DNA helicase UvrD\/PcrA [EC:5.6.2.4]" }, { "name":"R0135_16955 sbcB; (GenBank) exodeoxyribonuclease I\tK01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]" }, { "name":"R0135_00825 xseA; (GenBank) exodeoxyribonuclease VII large subunit\tK03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]" }, { "name":"R0135_00785 recJ; (GenBank) single-stranded-DNA-specific exonuclease RecJ\tK07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]" }, { "name":"R0135_15880 ssb; (GenBank) single-stranded DNA-binding protein\tK03111 ssb; single-strand DNA-binding protein" }, { "name":"R0135_00100 dnaE; (GenBank) DNA polymerase III subunit alpha\tK02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]" }, { "name":"R0135_11750 dnaN; (GenBank) DNA polymerase III subunit beta\tK02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]" }, { "name":"R0135_03595 dnaX; (GenBank) DNA polymerase III subunit gamma\/tau\tK02343 dnaX; DNA polymerase III subunit gamma\/tau [EC:2.7.7.7]" }, { "name":"R0135_08410 holA; (GenBank) DNA polymerase III subunit delta\tK02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]" }, { "name":"R0135_03080 DNA polymerase III subunit delta'\tK02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]" }, { "name":"R0135_01445 3'-5' exonuclease\tK02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]" }, { "name":"R0135_02925 dnaQ; (GenBank) DNA polymerase III subunit epsilon\tK02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]" }, { "name":"R0135_01620 DNA polymerase III subunit chi\tK02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7]" }, { "name":"R0135_02180 ligA; (GenBank) NAD-dependent DNA ligase LigA\tK01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]" } ] }, { "name":"03440 Homologous recombination [PATH:cvb03440]", "children":[ { "name":"R0135_00785 recJ; (GenBank) single-stranded-DNA-specific exonuclease RecJ\tK07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]" }, { "name":"R0135_15880 ssb; (GenBank) single-stranded DNA-binding protein\tK03111 ssb; single-strand DNA-binding protein" }, { "name":"R0135_11755 recF; (GenBank) DNA replication\/repair protein RecF\tK03629 recF; DNA replication and repair protein RecF" }, { "name":"R0135_01825 recO; (GenBank) DNA repair protein RecO\tK03584 recO; DNA repair protein RecO (recombination protein O)" }, { "name":"R0135_03585 recR; (GenBank) recombination mediator RecR\tK06187 recR; recombination protein RecR" }, { "name":"R0135_05330 recA; (GenBank) recombinase RecA\tK03553 recA; recombination protein RecA" }, { "name":"R0135_11995 polA; (GenBank) DNA polymerase I\tK02335 polA; DNA polymerase I [EC:2.7.7.7]" }, { "name":"R0135_09215 ruvA; (GenBank) Holliday junction branch migration protein RuvA\tK03550 ruvA; holliday junction DNA helicase RuvA" }, { "name":"R0135_09210 ruvB; (GenBank) Holliday junction branch migration DNA helicase RuvB\tK03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]" }, { "name":"R0135_09220 ruvC; (GenBank) crossover junction endodeoxyribonuclease RuvC\tK01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]" }, { "name":"R0135_11540 recG; (GenBank) ATP-dependent DNA helicase RecG\tK03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]" }, { "name":"R0135_14200 ATP-binding protein\tK03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]" }, { "name":"R0135_00100 dnaE; (GenBank) DNA polymerase III subunit alpha\tK02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]" }, { "name":"R0135_11750 dnaN; (GenBank) DNA polymerase III subunit beta\tK02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]" }, { "name":"R0135_03595 dnaX; (GenBank) DNA polymerase III subunit gamma\/tau\tK02343 dnaX; DNA polymerase III subunit gamma\/tau [EC:2.7.7.7]" }, { "name":"R0135_08410 holA; (GenBank) DNA polymerase III subunit delta\tK02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]" }, { "name":"R0135_03080 DNA polymerase III subunit delta'\tK02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]" }, { "name":"R0135_01445 3'-5' exonuclease\tK02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]" }, { "name":"R0135_02925 dnaQ; (GenBank) DNA polymerase III subunit epsilon\tK02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]" }, { "name":"R0135_01620 DNA polymerase III subunit chi\tK02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7]" }, { "name":"R0135_12660 primosomal protein N'\tK04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]" } ] }, { "name":"03450 Non-homologous end-joining" }, { "name":"03460 Fanconi anemia pathway" } ] }, { "name":"09126 Chromosome", "children":[ { "name":"03082 ATP-dependent chromatin remodeling" }, { "name":"03083 Polycomb repressive complex" } ] }, { "name":"09125 Information processing in viruses", "children":[ { "name":"03230 Viral genome structure" }, { "name":"03240 Viral replication" }, { "name":"03250 Viral life cycle - HIV-1 [PATH:cvb03250]", "children":[ { "name":"R0135_06875 peptidylprolyl isomerase\tK03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8]" } ] }, { "name":"03260 Virion - Human immunodeficiency virus" }, { "name":"03271 Virion - Rotavirus" }, { "name":"03262 Virion - Coronavirus" }, { "name":"03261 Virion - Influenza virus" }, { "name":"03263 Virion - Enterovirus" }, { "name":"03264 Virion - Flavivirus and Alphavirus" }, { "name":"03265 Virion - Ebolavirus, Lyssavirus and Morbillivirus" }, { "name":"03273 Virion - Lassa virus and SFTS virus" }, { "name":"03272 Virion - Hepatitis viruses", "children":[ { "name":"R0135_13630 prolyl oligopeptidase family serine peptidase\tK01278 DPP4; dipeptidyl-peptidase 4 [EC:3.4.14.5]" }, { "name":"R0135_13695 DPP IV N-terminal domain-containing protein\tK01278 DPP4; dipeptidyl-peptidase 4 [EC:3.4.14.5]" } ] }, { "name":"03266 Virion - Herpesvirus" }, { "name":"03268 Virion - Orthopoxvirus" }, { "name":"03267 Virion - Adenovirus" }, { "name":"03259 Virion - Bacteriophages T4 and T7" }, { "name":"03258 Virion - Bacteriophage lambda" } ] } ] }, { "name":"09130 Environmental Information Processing", "children":[ { "name":"09131 Membrane transport", "children":[ { "name":"02010 ABC transporters [PATH:cvb02010]", "children":[ { "name":"R0135_12775 modA; (GenBank) molybdate ABC transporter substrate-binding protein\tK02020 modA; molybdate transport system substrate-binding protein" }, { "name":"R0135_12770 modB; (GenBank) molybdate ABC transporter permease subunit\tK02018 modB; molybdate transport system permease protein" }, { "name":"R0135_12765 modC; (GenBank) molybdenum ABC transporter ATP-binding protein\tK02017 modC; molybdate transport system ATP-binding protein [EC:7.3.2.5]" }, { "name":"R0135_14630 ATP-binding cassette domain-containing protein\tK05776 modF; molybdate transport system ATP-binding protein" }, { "name":"R0135_13290 glycine betaine ABC transporter substrate-binding protein\tK05845 opuC; osmoprotectant transport system substrate-binding protein" }, { "name":"R0135_13285 ATP-binding cassette domain-containing protein\tK05847 opuA; osmoprotectant transport system ATP-binding protein [EC:7.6.2.9]" }, { "name":"R0135_07365 ABC transporter substrate-binding protein\tK07323 mlaC; phospholipid transport system substrate-binding protein" }, { "name":"R0135_17510 MlaD family protein\tK02067 mlaD; phospholipid\/cholesterol\/gamma-HCH transport system substrate-binding protein" }, { "name":"R0135_17520 ABC transporter permease\tK02066 mlaE; phospholipid\/cholesterol\/gamma-HCH transport system permease protein" }, { "name":"R0135_17515 ATP-binding cassette domain-containing protein\tK02065 mlaF; phospholipid\/cholesterol\/gamma-HCH transport system ATP-binding protein" }, { "name":"R0135_04985 ABC transporter substrate-binding protein\tK17321 glpV; glycerol transport system substrate-binding protein" }, { "name":"R0135_04970 sugar ABC transporter permease\tK17322 glpP; glycerol transport system permease protein" }, { "name":"R0135_04975 carbohydrate ABC transporter permease\tK17323 glpQ; glycerol transport system permease protein" }, { "name":"R0135_04960 ABC transporter ATP-binding protein\tK17324 glpS; glycerol transport system ATP-binding protein" }, { "name":"R0135_04965 ABC transporter ATP-binding protein\tK17325 glpT; glycerol transport system ATP-binding protein" }, { "name":"R0135_02200 phosphate ABC transporter substrate-binding protein\tK02040 pstS; phosphate transport system substrate-binding protein" }, { "name":"R0135_02205 ABC transporter permease subunit\tK02037 pstC; phosphate transport system permease protein" }, { "name":"R0135_02210 pstA; (GenBank) phosphate ABC transporter permease PstA\tK02038 pstA; phosphate transport system permease protein" }, { "name":"R0135_02215 pstB; (GenBank) phosphate ABC transporter ATP-binding protein PstB\tK02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1]" }, { "name":"R0135_05235 urtA; (GenBank) urea ABC transporter substrate-binding protein\tK11959 urtA; urea transport system substrate-binding protein" }, { "name":"R0135_05230 urtB; (GenBank) urea ABC transporter permease subunit UrtB\tK11960 urtB; urea transport system permease protein" }, { "name":"R0135_05225 urtC; (GenBank) urea ABC transporter permease subunit UrtC\tK11961 urtC; urea transport system permease protein" }, { "name":"R0135_05220 urtD; (GenBank) urea ABC transporter ATP-binding protein UrtD\tK11962 urtD; urea transport system ATP-binding protein" }, { "name":"R0135_05215 urtE; (GenBank) urea ABC transporter ATP-binding subunit UrtE\tK11963 urtE; urea transport system ATP-binding protein" }, { "name":"R0135_09930 peptide ABC transporter substrate-binding protein\tK15580 oppA; oligopeptide transport system substrate-binding protein" }, { "name":"R0135_09935 peptide ABC transporter substrate-binding protein\tK15580 oppA; oligopeptide transport system substrate-binding protein" }, { "name":"R0135_09940 ABC transporter permease subunit\tK15581 oppB; oligopeptide transport system permease protein" }, { "name":"R0135_09945 ABC transporter permease\tK15582 oppC; oligopeptide transport system permease protein" }, { "name":"R0135_16470 ABC transporter substrate-binding protein\tK13893 yejA; microcin C transport system substrate-binding protein" }, { "name":"R0135_16480 ABC transporter permease\tK13894 yejB; microcin C transport system permease protein" }, { "name":"R0135_16475 ABC transporter permease subunit\tK13895 yejE; microcin C transport system permease protein" }, { "name":"R0135_09950 dipeptide ABC transporter ATP-binding protein\tK13896 yejF; microcin C transport system ATP-binding protein" }, { "name":"R0135_14390 ABC transporter ATP-binding protein\tK09691 wzt; homopolymeric O-antigen transport system ATP-binding protein [EC:7.5.2.14]" }, { "name":"R0135_14385 ABC transporter permease\tK09692 tagG; teichoic acid transport system permease protein" }, { "name":"R0135_03435 FtsX-like permease family protein\tK09808 lolC_E_F; lipoprotein-releasing system permease protein" }, { "name":"R0135_03445 lipoprotein-releasing ABC transporter permease subunit\tK09808 lolC_E_F; lipoprotein-releasing system permease protein" }, { "name":"R0135_03440 lolD; (GenBank) lipoprotein-releasing ABC transporter ATP-binding protein LolD\tK09810 lolD; lipoprotein-releasing system ATP-binding protein [EC:7.6.2.-]" }, { "name":"R0135_02140 ccmD; (GenBank) heme exporter protein CcmD\tK02196 ccmD; heme exporter protein D" }, { "name":"R0135_02135 heme ABC transporter permease\tK02195 ccmC; heme exporter protein C" }, { "name":"R0135_02130 ccmB; (GenBank) heme exporter protein CcmB\tK02194 ccmB; heme exporter protein B" }, { "name":"R0135_02125 ccmA; (GenBank) cytochrome c biogenesis heme-transporting ATPase CcmA\tK02193 ccmA; heme exporter protein A [EC:7.6.2.5]" }, { "name":"R0135_01630 lptF; (GenBank) LPS export ABC transporter permease LptF\tK07091 lptF; lipopolysaccharide export system permease protein" }, { "name":"R0135_01635 lptG; (GenBank) LPS export ABC transporter permease LptG\tK11720 lptG; lipopolysaccharide export system permease protein" }, { "name":"R0135_07395 lptB; (GenBank) LPS export ABC transporter ATP-binding protein\tK06861 lptB; lipopolysaccharide export system ATP-binding protein [EC:7.5.2.5]" }, { "name":"R0135_11420 ftsX; (GenBank) permease-like cell division protein FtsX\tK09811 ftsX; cell division transport system permease protein" }, { "name":"R0135_11425 ftsE; (GenBank) cell division ATP-binding protein FtsE\tK09812 ftsE; cell division transport system ATP-binding protein" }, { "name":"R0135_05570 msbA; (GenBank) lipid A export permease\/ATP-binding protein MsbA\tK11085 msbA; ATP-binding cassette, subfamily B, bacterial MsbA [EC:7.5.2.6]" }, { "name":"R0135_05525 ABC transporter ATP-binding protein\/permease\tK24821 atm1; ATP-binding cassette, subfamily B, heavy metal transporter" }, { "name":"R0135_09595 ABC transporter ATP-binding protein\tK18893 vcaM; ATP-binding cassette, subfamily B, multidrug efflux pump" }, { "name":"R0135_03795 ABC transporter ATP-binding protein\tK18888 efrB; ATP-binding cassette, subfamily B, multidrug efflux pump" }, { "name":"R0135_07615 type I secretion system permease\/ATPase\tK12541 lapB; ATP-binding cassette, subfamily C, bacterial LapB" } ] }, { "name":"02060 Phosphotransferase system (PTS) [PATH:cvb02060]", "children":[ { "name":"R0135_11165 ptsP; (GenBank) phosphoenolpyruvate--protein phosphotransferase\tK08484 ptsP; phosphotransferase system, enzyme I, PtsP [EC:2.7.3.9]" }, { "name":"R0135_07420 HPr family phosphocarrier protein\tK08485 ptsO; phosphocarrier protein NPr" }, { "name":"R0135_07410 PTS sugar transporter subunit IIA\tK02806 ptsN; nitrogen PTS system EIIA component [EC:2.7.1.-]" } ] }, { "name":"03070 Bacterial secretion system [PATH:cvb03070]", "children":[ { "name":"R0135_12155 TolC family outer membrane protein\tK12340 tolC; outer membrane protein" }, { "name":"R0135_07035 gspD; (GenBank) type II secretion system secretin GspD\tK02453 gspD; general secretion pathway protein D" }, { "name":"R0135_16845 gspD; (GenBank) type II secretion system secretin GspD\tK02453 gspD; general secretion pathway protein D" }, { "name":"R0135_07040 gspC; (GenBank) type II secretion system protein GspC\tK02452 gspC; general secretion pathway protein C" }, { "name":"R0135_07025 gspF; (GenBank) type II secretion system inner membrane protein GspF\tK02455 gspF; general secretion pathway protein F" }, { "name":"R0135_16800 type II secretion system F family protein\tK02455 gspF; general secretion pathway protein F" }, { "name":"R0135_04725 type II secretion system protein GspG\tK02456 gspG; general secretion pathway protein G" }, { "name":"R0135_07020 gspG; (GenBank) type II secretion system major pseudopilin GspG\tK02456 gspG; general secretion pathway protein G" }, { "name":"R0135_16805 gspG; (GenBank) type II secretion system major pseudopilin GspG\tK02456 gspG; general secretion pathway protein G" }, { "name":"R0135_07015 type II secretion system protein\tK02457 gspH; general secretion pathway protein H" }, { "name":"R0135_16810 prepilin-type N-terminal cleavage\/methylation domain-containing protein\tK02457 gspH; general secretion pathway protein H" }, { "name":"R0135_07010 gspI; (GenBank) type II secretion system minor pseudopilin GspI\tK02458 gspI; general secretion pathway protein I" }, { "name":"R0135_16815 prepilin-type N-terminal cleavage\/methylation domain-containing protein\tK02458 gspI; general secretion pathway protein I" }, { "name":"R0135_07005 gspJ; (GenBank) type II secretion system minor pseudopilin GspJ\tK02459 gspJ; general secretion pathway protein J" }, { "name":"R0135_16820 prepilin-type N-terminal cleavage\/methylation domain-containing protein\tK02459 gspJ; general secretion pathway protein J" }, { "name":"R0135_07000 gspK; (GenBank) type II secretion system minor pseudopilin GspK\tK02460 gspK; general secretion pathway protein K" }, { "name":"R0135_16825 hypothetical protein\tK02460 gspK; general secretion pathway protein K" }, { "name":"R0135_06995 gspL; (GenBank) type II secretion system protein GspL\tK02461 gspL; general secretion pathway protein L" }, { "name":"R0135_16830 PilN domain-containing protein\tK02461 gspL; general secretion pathway protein L" }, { "name":"R0135_06990 gspM; (GenBank) type II secretion system protein GspM\tK02462 gspM; general secretion pathway protein M" }, { "name":"R0135_16835 gspM; (GenBank) type II secretion system protein GspM\tK02462 gspM; general secretion pathway protein M" }, { "name":"R0135_07030 gspE; (GenBank) type II secretion system ATPase GspE\tK02454 gspE; general secretion pathway protein E [EC:7.4.2.8]" }, { "name":"R0135_12080 GspE\/PulE family protein\tK02454 gspE; general secretion pathway protein E [EC:7.4.2.8]" }, { "name":"R0135_16795 ATPase, T2SS\/T4P\/T4SS family\tK02454 gspE; general secretion pathway protein E [EC:7.4.2.8]" }, { "name":"R0135_00940 secD; (GenBank) protein translocase subunit SecD\tK03072 secD; preprotein translocase subunit SecD" }, { "name":"R0135_00945 secF; (GenBank) protein translocase subunit SecF\tK03074 secF; preprotein translocase subunit SecF" }, { "name":"R0135_15650 secE; (GenBank) preprotein translocase subunit SecE\tK03073 secE; preprotein translocase subunit SecE" }, { "name":"R0135_08710 secG; (GenBank) preprotein translocase subunit SecG\tK03075 secG; preprotein translocase subunit SecG" }, { "name":"R0135_15835 secY; (GenBank) preprotein translocase subunit SecY\tK03076 secY; preprotein translocase subunit SecY" }, { "name":"R0135_02530 yajC; (GenBank) preprotein translocase subunit YajC\tK03210 yajC; preprotein translocase subunit YajC" }, { "name":"R0135_11725 yidC; (GenBank) membrane protein insertase YidC\tK03217 yidC; YidC\/Oxa1 family membrane protein insertase" }, { "name":"R0135_07180 secA; (GenBank) preprotein translocase subunit SecA\tK03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]" }, { "name":"R0135_11430 ftsY; (GenBank) signal recognition particle-docking protein FtsY\tK03110 ftsY; fused signal recognition particle receptor" }, { "name":"R0135_12410 secB; (GenBank) protein-export chaperone SecB\tK03071 secB; preprotein translocase subunit SecB" }, { "name":"R0135_00735 ffh; (GenBank) signal recognition particle protein\tK03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]" }, { "name":"R0135_12605 tatA; (GenBank) twin-arginine translocase TatA\/TatE family subunit\tK03116 tatA; sec-independent protein translocase protein TatA" }, { "name":"R0135_12600 tatB; (GenBank) Sec-independent protein translocase protein TatB\tK03117 tatB; sec-independent protein translocase protein TatB" }, { "name":"R0135_12595 tatC; (GenBank) twin-arginine translocase subunit TatC\tK03118 tatC; sec-independent protein translocase protein TatC" } ] } ] }, { "name":"09132 Signal transduction", "children":[ { "name":"02020 Two-component system [PATH:cvb02020]", "children":[ { "name":"R0135_02195 phoR; (GenBank) phosphate regulon sensor histidine kinase PhoR\tK07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]" }, { "name":"R0135_02190 phoB; (GenBank) phosphate regulon transcriptional regulator PhoB\tK07657 phoB; two-component system, OmpR family, phosphate regulon response regulator PhoB" }, { "name":"R0135_10725 alkaline phosphatase\tK01077 ALP; alkaline phosphatase [EC:3.1.3.1]" }, { "name":"R0135_04605 alkaline phosphatase D family protein\tK01113 phoD; alkaline phosphatase D [EC:3.1.3.1]" }, { "name":"R0135_02200 phosphate ABC transporter substrate-binding protein\tK02040 pstS; phosphate transport system substrate-binding protein" }, { "name":"R0135_01795 Do family serine endopeptidase\tK04771 degP; serine protease Do [EC:3.4.21.107]" }, { "name":"R0135_08150 trypsin-like peptidase domain-containing protein\tK04771 degP; serine protease Do [EC:3.4.21.107]" }, { "name":"R0135_15210 Do family serine endopeptidase\tK04771 degP; serine protease Do [EC:3.4.21.107]" }, { "name":"R0135_13760 ATP-binding protein\tK07642 baeS; two-component system, OmpR family, sensor histidine kinase BaeS [EC:2.7.13.3]" }, { "name":"R0135_13755 response regulator\tK07664 baeR; two-component system, OmpR family, response regulator BaeR" }, { "name":"R0135_06410 TolC family protein\tK07796 cusC; outer membrane protein, copper\/silver efflux system" }, { "name":"R0135_06415 efflux RND transporter periplasmic adaptor subunit\tK07798 cusB; membrane fusion protein, copper\/silver efflux system" }, { "name":"R0135_06420 CusA\/CzcA family heavy metal efflux RND transporter\tK07787 cusA; copper\/silver efflux system protein" }, { "name":"R0135_16135 flagellin\tK02406 fliC; flagellin" }, { "name":"R0135_16270 RNA polymerase sigma factor FliA\tK02405 fliA; RNA polymerase sigma factor FliA" }, { "name":"R0135_16275 flagellar motor protein\tK02556 motA; chemotaxis protein MotA" }, { "name":"R0135_16300 pomA; (GenBank) flagellar motor protein PomA\tK02556 motA; chemotaxis protein MotA" }, { "name":"R0135_08310 COX15\/CtaA family protein\tK02259 COX15; heme a synthase [EC:1.17.99.9]" }, { "name":"R0135_11795 glycoside hydrolase family 68 protein\tK00692 sacB; levansucrase [EC:2.4.1.10]" }, { "name":"R0135_11745 dnaA; (GenBank) chromosomal replication initiator protein DnaA\tK02313 dnaA; chromosomal replication initiator protein" }, { "name":"R0135_05175 LytTR family DNA-binding domain-containing protein\tK07705 lytT; two-component system, LytTR family, response regulator LytT" }, { "name":"R0135_12260 LytTR family DNA-binding domain-containing protein\tK07705 lytT; two-component system, LytTR family, response regulator LytT" }, { "name":"R0135_09660 sensor histidine kinase\tK08082 algZ; two-component system, LytTR family, sensor histidine kinase AlgZ [EC:2.7.13.3]" }, { "name":"R0135_09655 LytTR family DNA-binding domain-containing protein\tK08083 algR; two-component system, LytTR family, response regulator AlgR" }, { "name":"R0135_00210 csrA; (GenBank) carbon storage regulator CsrA\tK03563 csrA; carbon storage regulator" }, { "name":"R0135_00015 glnD; (GenBank) [protein-PII] uridylyltransferase\tK00990 glnD; [protein-PII] uridylyltransferase [EC:2.7.7.59]" }, { "name":"R0135_12425 glnL; (GenBank) nitrogen regulation protein NR(II)\tK07708 glnL; two-component system, NtrC family, nitrogen regulation sensor histidine kinase GlnL [EC:2.7.13.3]" }, { "name":"R0135_12420 ntrC; (GenBank) nitrogen regulation protein NR(I)\tK07712 glnG; two-component system, NtrC family, nitrogen regulation response regulator GlnG" }, { "name":"R0135_08950 glutamine synthetase family protein\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]" }, { "name":"R0135_09260 glutamine synthetase family protein\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]" }, { "name":"R0135_10760 glutamine synthetase family protein\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]" }, { "name":"R0135_12435 glnA; (GenBank) glutamate--ammonia ligase\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]" }, { "name":"R0135_12885 glutamine synthetase family protein\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]" }, { "name":"R0135_08625 sigma-54 dependent transcriptional regulator\tK07713 zraR; two-component system, NtrC family, response regulator HydG" }, { "name":"R0135_00330 acetyl-CoA C-acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" }, { "name":"R0135_03970 acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" }, { "name":"R0135_04435 acetyl-CoA C-acyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" }, { "name":"R0135_05075 acetyl-CoA C-acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" }, { "name":"R0135_11080 acetyl-CoA C-acyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" }, { "name":"R0135_11085 acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" }, { "name":"R0135_17030 HAMP domain-containing sensor histidine kinase\tK02668 pilS; two-component system, NtrC family, sensor histidine kinase PilS [EC:2.7.13.3]" }, { "name":"R0135_17025 sigma-54 dependent transcriptional regulator\tK02667 pilR; two-component system, NtrC family, response regulator PilR" }, { "name":"R0135_07400 RNA polymerase factor sigma-54\tK03092 rpoN; RNA polymerase sigma-54 factor" }, { "name":"R0135_07145 pilin\tK02650 pilA; type IV pilus assembly protein PilA" }, { "name":"R0135_14720 prepilin-type N-terminal cleavage\/methylation domain-containing protein\tK02650 pilA; type IV pilus assembly protein PilA" }, { "name":"R0135_00870 CheR family methyltransferase\tK13924 cheBR; two-component system, chemotaxis family, CheB\/CheR fusion protein [EC:2.1.1.80 3.1.1.61]" }, { "name":"R0135_15175 chemotaxis protein CheB\tK13924 cheBR; two-component system, chemotaxis family, CheB\/CheR fusion protein [EC:2.1.1.80 3.1.1.61]" }, { "name":"R0135_10610 TRAP transporter substrate-binding protein\tK11688 dctP; TRAP-type transport system periplasmic protein" }, { "name":"R0135_11600 TRAP transporter substrate-binding protein\tK11688 dctP; TRAP-type transport system periplasmic protein" }, { "name":"R0135_10605 TRAP transporter small permease\tK11689 dctQ; TRAP-type transport system small permease protein" }, { "name":"R0135_11585 TRAP transporter small permease subunit\tK11689 dctQ; TRAP-type transport system small permease protein" }, { "name":"R0135_10600 TRAP transporter large permease\tK11690 dctM; TRAP-type transport system large permease protein" }, { "name":"R0135_11590 TRAP transporter large permease subunit\tK11690 dctM; TRAP-type transport system large permease protein" }, { "name":"R0135_00865 response regulator\tK14987 fixJ; two-component system, LuxR family, response regulator FixJ" }, { "name":"R0135_16170 ATP-binding protein\tK10942 flrB; two-component system, sensor histidine kinase FlrB [EC:2.7.13.3]" }, { "name":"R0135_16175 sigma-54 dependent transcriptional regulator\tK10943 flrC; two-component system, response regulator FlrC" }, { "name":"R0135_00820 Crp\/Fnr family transcriptional regulator\tK10914 crp; CRP\/FNR family transcriptional regulator, cyclic AMP receptor protein" }, { "name":"R0135_05940 Crp\/Fnr family transcriptional regulator\tK10914 crp; CRP\/FNR family transcriptional regulator, cyclic AMP receptor protein" }, { "name":"R0135_14540 crp; (GenBank) cAMP-activated global transcriptional regulator CRP\tK10914 crp; CRP\/FNR family transcriptional regulator, cyclic AMP receptor protein" }, { "name":"R0135_13335 light-harvesting protein\tK08930 pucA; light-harvesting protein B-800-850 alpha chain" }, { "name":"R0135_13340 pufB; (GenBank) light-harvesting antenna LH1, beta subunit\tK08939 pucB; light-harvesting protein B-800-850 beta chain" }, { "name":"R0135_17215 pufM; (GenBank) photosynthetic reaction center subunit M\tK08929 pufM; photosynthetic reaction center M subunit" }, { "name":"R0135_17210 pufL; (GenBank) photosynthetic reaction center subunit L\tK08928 pufL; photosynthetic reaction center L subunit" }, { "name":"R0135_17230 pufA; (GenBank) light-harvesting antenna LH1, alpha subunit\tK08926 pufA; light-harvesting complex 1 alpha chain" }, { "name":"R0135_17225 pufB; (GenBank) light-harvesting antenna LH1, beta subunit\tK08927 pufB; light-harvesting complex 1 beta chain" }, { "name":"R0135_17260 puhA; (GenBank) photosynthetic reaction center subunit H\tK13991 puhA; photosynthetic reaction center H subunit" }, { "name":"R0135_07310 petA; (GenBank) ubiquinol-cytochrome c reductase iron-sulfur subunit\tK00411 UQCRFS1; ubiquinol-cytochrome c reductase iron-sulfur subunit [EC:7.1.1.8]" }, { "name":"R0135_07305 ubiquinol-cytochrome c reductase\tK00412 CYTB; ubiquinol-cytochrome c reductase cytochrome b subunit" }, { "name":"R0135_11770 c-type cytochrome\tK08738 CYC; cytochrome c" }, { "name":"R0135_01725 ccoN; (GenBank) cytochrome-c oxidase, cbb3-type subunit I\tK00404 ccoN; cytochrome c oxidase cbb3-type subunit I [EC:7.1.1.9]" }, { "name":"R0135_01720 ccoO; (GenBank) cytochrome-c oxidase, cbb3-type subunit II\tK00405 ccoO; cytochrome c oxidase cbb3-type subunit II" }, { "name":"R0135_01715 cbb3-type cytochrome c oxidase subunit 3\tK00407 ccoQ; cytochrome c oxidase cbb3-type subunit IV" }, { "name":"R0135_01710 ccoP; (GenBank) cytochrome-c oxidase, cbb3-type subunit III\tK00406 ccoP; cytochrome c oxidase cbb3-type subunit III" }, { "name":"R0135_06120 cytochrome ubiquinol oxidase subunit I\tK00425 cydA; cytochrome bd ubiquinol oxidase subunit I [EC:7.1.1.7]" }, { "name":"R0135_06125 cydB; (GenBank) cytochrome d ubiquinol oxidase subunit II\tK00426 cydB; cytochrome bd ubiquinol oxidase subunit II [EC:7.1.1.7]" }, { "name":"R0135_12155 TolC family outer membrane protein\tK12340 tolC; outer membrane protein" }, { "name":"R0135_07800 polysaccharide export protein\tK01991 wza; polysaccharide biosynthesis\/export protein" }, { "name":"R0135_10235 SLBB domain-containing protein\tK01991 wza; polysaccharide biosynthesis\/export protein" }, { "name":"R0135_00885 PAS domain-containing sensor histidine kinase\tK20975 K20975; two-component system, sensor histidine kinase [EC:2.7.13.3]" }, { "name":"R0135_16070 flgM; (GenBank) flagellar biosynthesis anti-sigma factor FlgM\tK02398 flgM; negative regulator of flagellin synthesis FlgM" } ] }, { "name":"04010 MAPK signaling pathway" }, { "name":"04013 MAPK signaling pathway - fly" }, { "name":"04016 MAPK signaling pathway - plant" }, { "name":"04011 MAPK signaling pathway - yeast" }, { "name":"04012 ErbB signaling pathway" }, { "name":"04014 Ras signaling pathway" }, { "name":"04015 Rap1 signaling pathway" }, { "name":"04310 Wnt signaling pathway" }, { "name":"04330 Notch signaling pathway" }, { "name":"04340 Hedgehog signaling pathway" }, { "name":"04341 Hedgehog signaling pathway - fly" }, { "name":"04350 TGF-beta signaling pathway" }, { "name":"04390 Hippo signaling pathway" }, { "name":"04391 Hippo signaling pathway - fly" }, { "name":"04392 Hippo signaling pathway - multiple species" }, { "name":"04370 VEGF signaling pathway" }, { "name":"04371 Apelin signaling pathway" }, { "name":"04630 JAK-STAT signaling pathway" }, { "name":"04064 NF-kappa B signaling pathway" }, { "name":"04668 TNF signaling pathway" }, { "name":"04066 HIF-1 signaling pathway" }, { "name":"04068 FoxO signaling pathway" }, { "name":"04020 Calcium signaling pathway" }, { "name":"04070 Phosphatidylinositol signaling system" }, { "name":"04072 Phospholipase D signaling pathway" }, { "name":"04071 Sphingolipid signaling pathway" }, { "name":"04024 cAMP signaling pathway" }, { "name":"04022 cGMP-PKG signaling pathway" }, { "name":"04151 PI3K-Akt signaling pathway" }, { "name":"04152 AMPK signaling pathway" }, { "name":"04150 mTOR signaling pathway" }, { "name":"04075 Plant hormone signal transduction" } ] }, { "name":"09133 Signaling molecules and interaction", "children":[ { "name":"04080 Neuroactive ligand-receptor interaction" }, { "name":"04082 Neuroactive ligand signaling" }, { "name":"04081 Hormone signaling" }, { "name":"04060 Cytokine-cytokine receptor interaction" }, { "name":"04061 Viral protein interaction with cytokine and cytokine receptor" }, { "name":"04512 ECM-receptor interaction" }, { "name":"04514 Cell adhesion molecule (CAM) interaction" }, { "name":"04517 IgSF CAM signaling" }, { "name":"04518 Integrin signaling" }, { "name":"04519 Cadherin signaling" } ] } ] }, { "name":"09140 Cellular Processes", "children":[ { "name":"09141 Transport and catabolism", "children":[ { "name":"04144 Endocytosis" }, { "name":"04145 Phagocytosis", "children":[ { "name":"R0135_10725 alkaline phosphatase\tK01077 ALP; alkaline phosphatase [EC:3.1.3.1]" } ] }, { "name":"04142 Lysosome biogenesis" }, { "name":"04146 Peroxisome [PATH:cvb04146]", "children":[ { "name":"R0135_01565 CaiB\/BaiF CoA-transferase family protein\tK01796 AMACR; alpha-methylacyl-CoA racemase [EC:5.1.99.4]" }, { "name":"R0135_05490 AMP-binding protein\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]" }, { "name":"R0135_05640 AMP-binding protein\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]" }, { "name":"R0135_02915 nudC; (GenBank) NAD(+) diphosphatase\tK03426 NUDT12_13; NAD+ diphosphatase [EC:3.6.1.22]" }, { "name":"R0135_03940 alanine--glyoxylate aminotransferase family protein\tK00830 AGXT; alanine-glyoxylate transaminase \/ serine-glyoxylate transaminase \/ serine-pyruvate transaminase [EC:2.6.1.44 2.6.1.45 2.6.1.51]" }, { "name":"R0135_02625 icd; (GenBank) NADP-dependent isocitrate dehydrogenase\tK00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]" }, { "name":"R0135_04930 isocitrate\/isopropylmalate family dehydrogenase\tK00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]" }, { "name":"R0135_00130 hydroxymethylglutaryl-CoA lyase\tK01640 HMGCL; hydroxymethylglutaryl-CoA lyase [EC:4.1.3.4]" }, { "name":"R0135_15570 hydroxymethylglutaryl-CoA lyase\tK01640 HMGCL; hydroxymethylglutaryl-CoA lyase [EC:4.1.3.4]" }, { "name":"R0135_16935 Fe-Mn family superoxide dismutase\tK04564 SOD2; superoxide dismutase, Fe-Mn family [EC:1.15.1.1]" } ] }, { "name":"04149 Peroxisome - yeast" }, { "name":"04140 Autophagy - animal" }, { "name":"04138 Autophagy - yeast" }, { "name":"04136 Autophagy - other" }, { "name":"04137 Mitophagy - animal" }, { "name":"04139 Mitophagy - yeast" }, { "name":"04148 Efferocytosis", "children":[ { "name":"R0135_07310 petA; (GenBank) ubiquinol-cytochrome c reductase iron-sulfur subunit\tK00411 UQCRFS1; ubiquinol-cytochrome c reductase iron-sulfur subunit [EC:7.1.1.8]" } ] } ] }, { "name":"09143 Cell growth and death", "children":[ { "name":"04110 Cell cycle" }, { "name":"04111 Cell cycle - yeast" }, { "name":"04112 Cell cycle - Caulobacter" }, { "name":"04113 Meiosis - yeast" }, { "name":"04114 Oocyte meiosis" }, { "name":"04210 Apoptosis" }, { "name":"04214 Apoptosis - fly" }, { "name":"04215 Apoptosis - multiple species" }, { "name":"04216 Ferroptosis" }, { "name":"04217 Necroptosis" }, { "name":"04115 p53 signaling pathway" }, { "name":"04218 Cellular senescence" }, { "name":"04156 Integrated stress response (ISR) signaling pathway [PATH:cvb04156]", "children":[ { "name":"R0135_02285 htpG; (GenBank) molecular chaperone HtpG\tK04079 HSP90A; molecular chaperone HtpG" }, { "name":"R0135_08235 tRNA-Met\tK14230 tRNA-Met; tRNA Met" }, { "name":"R0135_08700 tRNA-Met\tK14230 tRNA-Met; tRNA Met" }, { "name":"R0135_14300 tRNA-Ile\tK14230 tRNA-Met; tRNA Met" }, { "name":"R0135_16630 dnaK; (GenBank) molecular chaperone DnaK\tK04043 dnaK; molecular chaperone DnaK" }, { "name":"R0135_16930 groL; (GenBank) chaperonin GroEL\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]" }, { "name":"R0135_05510 gamma-glutamylcyclotransferase\tK07232 CHAC; glutathione-specific gamma-glutamylcyclotransferase [EC:4.3.2.7]" } ] } ] }, { "name":"09144 Cellular community - eukaryotes", "children":[ { "name":"04510 Focal adhesion" }, { "name":"04520 Adherens junction" }, { "name":"04530 Tight junction" }, { "name":"04540 Gap junction" }, { "name":"04550 Signaling pathways regulating pluripotency of stem cells" } ] }, { "name":"09145 Cellular community - prokaryotes", "children":[ { "name":"02024 Quorum sensing [PATH:cvb02024]", "children":[ { "name":"R0135_14970 hfq; (GenBank) RNA chaperone Hfq\tK03666 hfq; host factor-I protein" }, { "name":"R0135_14520 trpE; (GenBank) anthranilate synthase component I\tK01657 trpE; anthranilate synthase component I [EC:4.1.3.27]" }, { "name":"R0135_14525 aminodeoxychorismate\/anthranilate synthase component II\tK01658 trpG; anthranilate synthase component II [EC:4.1.3.27]" }, { "name":"R0135_15505 glycosyltransferase family 2 protein\tK12990 rfbF; rhamnosyltransferase [EC:2.4.1.-]" }, { "name":"R0135_01405 3-deoxy-7-phosphoheptulonate synthase\tK01626 E2.5.1.54; 3-deoxy-7-phosphoheptulonate synthase [EC:2.5.1.54]" }, { "name":"R0135_02970 3-deoxy-7-phosphoheptulonate synthase\tK01626 E2.5.1.54; 3-deoxy-7-phosphoheptulonate synthase [EC:2.5.1.54]" }, { "name":"R0135_10855 3-deoxy-7-phosphoheptulonate synthase\tK01626 E2.5.1.54; 3-deoxy-7-phosphoheptulonate synthase [EC:2.5.1.54]" }, { "name":"R0135_10770 APC family permease\tK20265 gadC; glutamate:GABA antiporter" }, { "name":"R0135_07965 extracellular solute-binding protein\tK02055 ABC.SP.S; putative spermidine\/putrescine transport system substrate-binding protein" }, { "name":"R0135_05490 AMP-binding protein\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]" }, { "name":"R0135_05640 AMP-binding protein\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]" }, { "name":"R0135_00820 Crp\/Fnr family transcriptional regulator\tK10914 crp; CRP\/FNR family transcriptional regulator, cyclic AMP receptor protein" }, { "name":"R0135_05940 Crp\/Fnr family transcriptional regulator\tK10914 crp; CRP\/FNR family transcriptional regulator, cyclic AMP receptor protein" }, { "name":"R0135_14540 crp; (GenBank) cAMP-activated global transcriptional regulator CRP\tK10914 crp; CRP\/FNR family transcriptional regulator, cyclic AMP receptor protein" }, { "name":"R0135_15480 ribA; (GenBank) GTP cyclohydrolase II\tK01497 ribA; GTP cyclohydrolase II [EC:3.5.4.25]" }, { "name":"R0135_15440 ribD; (GenBank) bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase\/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD\tK11752 ribD; diaminohydroxyphosphoribosylaminopyrimidine deaminase \/ 5-amino-6-(5-phosphoribosylamino)uracil reductase [EC:3.5.4.26 1.1.1.193]" }, { "name":"R0135_09930 peptide ABC transporter substrate-binding protein\tK15580 oppA; oligopeptide transport system substrate-binding protein" }, { "name":"R0135_09935 peptide ABC transporter substrate-binding protein\tK15580 oppA; oligopeptide transport system substrate-binding protein" }, { "name":"R0135_09940 ABC transporter permease subunit\tK15581 oppB; oligopeptide transport system permease protein" }, { "name":"R0135_09945 ABC transporter permease\tK15582 oppC; oligopeptide transport system permease protein" }, { "name":"R0135_16465 ABC transporter ATP-binding protein\tK02031 ddpD; peptide\/nickel transport system ATP-binding protein" }, { "name":"R0135_16460 ATP-binding cassette domain-containing protein\tK02032 ddpF; peptide\/nickel transport system ATP-binding protein" }, { "name":"R0135_11725 yidC; (GenBank) membrane protein insertase YidC\tK03217 yidC; YidC\/Oxa1 family membrane protein insertase" }, { "name":"R0135_10805 S8 family serine peptidase\tK14645 K14645; serine protease [EC:3.4.21.-]" }, { "name":"R0135_15650 secE; (GenBank) preprotein translocase subunit SecE\tK03073 secE; preprotein translocase subunit SecE" }, { "name":"R0135_08710 secG; (GenBank) preprotein translocase subunit SecG\tK03075 secG; preprotein translocase subunit SecG" }, { "name":"R0135_15835 secY; (GenBank) preprotein translocase subunit SecY\tK03076 secY; preprotein translocase subunit SecY" }, { "name":"R0135_02530 yajC; (GenBank) preprotein translocase subunit YajC\tK03210 yajC; preprotein translocase subunit YajC" }, { "name":"R0135_07180 secA; (GenBank) preprotein translocase subunit SecA\tK03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]" }, { "name":"R0135_11430 ftsY; (GenBank) signal recognition particle-docking protein FtsY\tK03110 ftsY; fused signal recognition particle receptor" }, { "name":"R0135_12410 secB; (GenBank) protein-export chaperone SecB\tK03071 secB; preprotein translocase subunit SecB" }, { "name":"R0135_00735 ffh; (GenBank) signal recognition particle protein\tK03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]" } ] }, { "name":"05111 Biofilm formation - Vibrio cholerae" }, { "name":"02025 Biofilm formation - Pseudomonas aeruginosa" }, { "name":"02026 Biofilm formation - Escherichia coli" } ] }, { "name":"09142 Cell motility", "children":[ { "name":"02030 Bacterial chemotaxis [PATH:cvb02030]", "children":[ { "name":"R0135_00870 CheR family methyltransferase\tK13924 cheBR; two-component system, chemotaxis family, CheB\/CheR fusion protein [EC:2.1.1.80 3.1.1.61]" }, { "name":"R0135_15175 chemotaxis protein CheB\tK13924 cheBR; two-component system, chemotaxis family, CheB\/CheR fusion protein [EC:2.1.1.80 3.1.1.61]" }, { "name":"R0135_16190 fliG; (GenBank) flagellar motor switch protein FliG\tK02410 fliG; flagellar motor switch protein FliG" }, { "name":"R0135_16220 FliM\/FliN family flagellar motor switch protein\tK02416 fliM; flagellar motor switch protein FliM" }, { "name":"R0135_16225 fliN; (GenBank) flagellar motor switch protein FliN\tK02417 fliN; flagellar motor switch protein FliN" }, { "name":"R0135_16275 flagellar motor protein\tK02556 motA; chemotaxis protein MotA" }, { "name":"R0135_16300 pomA; (GenBank) flagellar motor protein PomA\tK02556 motA; chemotaxis protein MotA" }, { "name":"R0135_16280 OmpA family protein\tK02557 motB; chemotaxis protein MotB" }, { "name":"R0135_16295 flagellar motor protein MotB\tK02557 motB; chemotaxis protein MotB" } ] }, { "name":"02040 Flagellar assembly [PATH:cvb02040]", "children":[ { "name":"R0135_16180 fliE; (GenBank) flagellar hook-basal body complex protein FliE\tK02408 fliE; flagellar hook-basal body complex protein FliE" }, { "name":"R0135_16185 fliF; (GenBank) flagellar basal-body MS-ring\/collar protein FliF\tK02409 fliF; flagellar M-ring protein FliF" }, { "name":"R0135_16190 fliG; (GenBank) flagellar motor switch protein FliG\tK02410 fliG; flagellar motor switch protein FliG" }, { "name":"R0135_16195 FliH\/SctL family protein\tK02411 fliH; flagellar assembly protein FliH" }, { "name":"R0135_16200 FliI\/YscN family ATPase\tK02412 fliI; flagellum-specific ATP synthase [EC:7.4.2.8]" }, { "name":"R0135_16205 fliJ; (GenBank) flagellar export protein FliJ\tK02413 fliJ; flagellar protein FliJ" }, { "name":"R0135_16210 flagellar hook-length control protein FliK\tK02414 fliK; flagellar hook-length control protein FliK" }, { "name":"R0135_16215 flagellar basal body-associated FliL family protein\tK02415 fliL; flagellar protein FliL" }, { "name":"R0135_16220 FliM\/FliN family flagellar motor switch protein\tK02416 fliM; flagellar motor switch protein FliM" }, { "name":"R0135_16225 fliN; (GenBank) flagellar motor switch protein FliN\tK02417 fliN; flagellar motor switch protein FliN" }, { "name":"R0135_16230 fliO; (GenBank) flagellar biosynthetic protein FliO\tK02418 fliO; flagellar protein FliO\/FliZ" }, { "name":"R0135_16235 fliP; (GenBank) flagellar type III secretion system pore protein FliP\tK02419 fliP; flagellar biosynthesis protein FliP" }, { "name":"R0135_16240 fliQ; (GenBank) flagellar biosynthesis protein FliQ\tK02420 fliQ; flagellar biosynthesis protein FliQ" }, { "name":"R0135_16245 fliR; (GenBank) flagellar biosynthetic protein FliR\tK02421 fliR; flagellar biosynthesis protein FliR" }, { "name":"R0135_16255 flhA; (GenBank) flagellar biosynthesis protein FlhA\tK02400 flhA; flagellar biosynthesis protein FlhA" }, { "name":"R0135_16250 flhB; (GenBank) flagellar biosynthesis protein FlhB\tK02401 flhB; flagellar biosynthesis protein FlhB" }, { "name":"R0135_16075 flgA; (GenBank) flagellar basal body P-ring formation chaperone FlgA\tK02386 flgA; flagellar basal body P-ring formation protein FlgA" }, { "name":"R0135_16080 flgB; (GenBank) flagellar basal body rod protein FlgB\tK02387 flgB; flagellar basal-body rod protein FlgB" }, { "name":"R0135_16085 flgC; (GenBank) flagellar basal body rod protein FlgC\tK02388 flgC; flagellar basal-body rod protein FlgC" }, { "name":"R0135_16090 flagellar hook capping FlgD N-terminal domain-containing protein\tK02389 flgD; flagellar basal-body rod modification protein FlgD" }, { "name":"R0135_16095 flgE; (GenBank) flagellar hook protein FlgE\tK02390 flgE; flagellar hook protein FlgE" }, { "name":"R0135_16100 flagellar basal body rod protein FlgF\tK02391 flgF; flagellar basal-body rod protein FlgF" }, { "name":"R0135_16105 flgG; (GenBank) flagellar basal-body rod protein FlgG\tK02392 flgG; flagellar basal-body rod protein FlgG" }, { "name":"R0135_16110 flgH; (GenBank) flagellar basal body L-ring protein FlgH\tK02393 flgH; flagellar L-ring protein FlgH" }, { "name":"R0135_16115 flagellar basal body P-ring protein FlgI\tK02394 flgI; flagellar P-ring protein FlgI" }, { "name":"R0135_16120 flgJ; (GenBank) flagellar assembly peptidoglycan hydrolase FlgJ\tK02395 flgJ; peptidoglycan hydrolase FlgJ" }, { "name":"R0135_16125 flgK; (GenBank) flagellar hook-associated protein FlgK\tK02396 flgK; flagellar hook-associated protein 1" }, { "name":"R0135_16130 flgL; (GenBank) flagellar hook-associated protein FlgL\tK02397 flgL; flagellar hook-associated protein 3 FlgL" }, { "name":"R0135_16135 flagellin\tK02406 fliC; flagellin" }, { "name":"R0135_16145 fliD; (GenBank) flagellar filament capping protein FliD\tK02407 fliD; flagellar hook-associated protein 2" }, { "name":"R0135_16150 fliS; (GenBank) flagellar export chaperone FliS\tK02422 fliS; flagellar secretion chaperone FliS" }, { "name":"R0135_16275 flagellar motor protein\tK02556 motA; chemotaxis protein MotA" }, { "name":"R0135_16300 pomA; (GenBank) flagellar motor protein PomA\tK02556 motA; chemotaxis protein MotA" }, { "name":"R0135_16280 OmpA family protein\tK02557 motB; chemotaxis protein MotB" }, { "name":"R0135_16295 flagellar motor protein MotB\tK02557 motB; chemotaxis protein MotB" }, { "name":"R0135_16070 flgM; (GenBank) flagellar biosynthesis anti-sigma factor FlgM\tK02398 flgM; negative regulator of flagellin synthesis FlgM" }, { "name":"R0135_16065 flagellar protein FlgN\tK02399 flgN; flagellar biosynthesis protein FlgN" }, { "name":"R0135_14325 rpoD; (GenBank) RNA polymerase sigma factor RpoD\tK03086 rpoD; RNA polymerase primary sigma factor" }, { "name":"R0135_07400 RNA polymerase factor sigma-54\tK03092 rpoN; RNA polymerase sigma-54 factor" }, { "name":"R0135_16175 sigma-54 dependent transcriptional regulator\tK10943 flrC; two-component system, response regulator FlrC" }, { "name":"R0135_16270 RNA polymerase sigma factor FliA\tK02405 fliA; RNA polymerase sigma factor FliA" } ] }, { "name":"04814 Motor proteins" }, { "name":"04820 Cytoskeleton in muscle cells", "children":[ { "name":"R0135_05390 eno; (GenBank) phosphopyruvate hydratase\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]" } ] }, { "name":"04810 Regulation of actin cytoskeleton" } ] } ] }, { "name":"09150 Organismal Systems", "children":[ { "name":"09151 Immune system", "children":[ { "name":"04640 Hematopoietic cell lineage" }, { "name":"04610 Complement and coagulation cascades" }, { "name":"04611 Platelet activation" }, { "name":"04613 Neutrophil extracellular trap formation" }, { "name":"04620 Toll-like receptor signaling pathway" }, { "name":"04624 Toll and Imd signaling pathway" }, { "name":"04621 NOD-like receptor signaling pathway" }, { "name":"04622 RIG-I-like receptor signaling pathway" }, { "name":"04623 Cytosolic DNA-sensing pathway" }, { "name":"04625 C-type lectin receptor signaling pathway" }, { "name":"04650 Natural killer cell mediated cytotoxicity" }, { "name":"04612 Antigen processing and presentation" }, { "name":"04660 T cell receptor signaling pathway" }, { "name":"04658 Th1 and Th2 cell differentiation" }, { "name":"04659 Th17 cell differentiation" }, { "name":"04657 IL-17 signaling pathway" }, { "name":"04662 B cell receptor signaling pathway" }, { "name":"04664 Fc epsilon RI signaling pathway" }, { "name":"04666 Fc gamma R-mediated phagosome formation" }, { "name":"04670 Leukocyte transendothelial migration" }, { "name":"04672 Intestinal immune network for IgA production" }, { "name":"04062 Chemokine signaling pathway" } ] }, { "name":"09152 Endocrine system", "children":[ { "name":"04911 Insulin secretion" }, { "name":"04910 Insulin signaling pathway" }, { "name":"04922 Glucagon signaling pathway" }, { "name":"04923 Regulation of lipolysis in adipocytes" }, { "name":"04920 Adipocytokine signaling pathway" }, { "name":"03320 PPAR signaling pathway" }, { "name":"04929 GnRH secretion" }, { "name":"04912 GnRH signaling pathway" }, { "name":"04913 Ovarian steroidogenesis" }, { "name":"04915 Estrogen signaling pathway" }, { "name":"04914 Progesterone-mediated oocyte maturation" }, { "name":"04917 Prolactin signaling pathway" }, { "name":"04921 Oxytocin signaling pathway" }, { "name":"04926 Relaxin signaling pathway" }, { "name":"04935 Growth hormone synthesis, secretion and action" }, { "name":"04918 Thyroid hormone synthesis" }, { "name":"04919 Thyroid hormone signaling pathway" }, { "name":"04928 Parathyroid hormone synthesis, secretion and action" }, { "name":"04916 Melanogenesis" }, { "name":"04924 Renin secretion" }, { "name":"04614 Renin-angiotensin system" }, { "name":"04925 Aldosterone synthesis and secretion" }, { "name":"04927 Cortisol synthesis and secretion" } ] }, { "name":"09153 Circulatory system", "children":[ { "name":"04260 Cardiac muscle contraction" }, { "name":"04261 Adrenergic signaling in cardiomyocytes" }, { "name":"04270 Vascular smooth muscle contraction" } ] }, { "name":"09154 Digestive system", "children":[ { "name":"04970 Salivary secretion" }, { "name":"04971 Gastric acid secretion" }, { "name":"04972 Pancreatic secretion" }, { "name":"04976 Bile secretion" }, { "name":"04973 Carbohydrate digestion and absorption" }, { "name":"04974 Protein digestion and absorption" }, { "name":"04975 Fat digestion and absorption" }, { "name":"04979 Cholesterol metabolism" }, { "name":"04977 Vitamin digestion and absorption" }, { "name":"04981 Folate transport and metabolism [PATH:cvb04981]", "children":[ { "name":"R0135_11220 5-formyltetrahydrofolate cyclo-ligase\tK01934 MTHFS; 5-formyltetrahydrofolate cyclo-ligase [EC:6.3.3.2]" }, { "name":"R0135_11145 dihydrofolate reductase\tK00287 DHFR; dihydrofolate reductase [EC:1.5.1.3]" }, { "name":"R0135_15430 glyA; (GenBank) serine hydroxymethyltransferase\tK00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]" }, { "name":"R0135_11150 thymidylate synthase\tK00560 thyA; thymidylate synthase [EC:2.1.1.45]" }, { "name":"R0135_02980 metH; (GenBank) methionine synthase\tK00548 metH; 5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]" } ] }, { "name":"04980 Cobalamin transport and metabolism [PATH:cvb04980]", "children":[ { "name":"R0135_02575 meaB; (GenBank) methylmalonyl Co-A mutase-associated GTPase MeaB\tK07588 MMAA; GTPase [EC:3.6.5.-]" }, { "name":"R0135_16430 meaB; (GenBank) methylmalonyl Co-A mutase-associated GTPase MeaB\tK07588 MMAA; GTPase [EC:3.6.5.-]" }, { "name":"R0135_02570 scpA; (GenBank) methylmalonyl-CoA mutase\tK01847 MUT; methylmalonyl-CoA mutase [EC:5.4.99.2]" }, { "name":"R0135_02980 metH; (GenBank) methionine synthase\tK00548 metH; 5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]" } ] }, { "name":"04978 Mineral absorption" } ] }, { "name":"09155 Excretory system", "children":[ { "name":"04962 Vasopressin-regulated water reabsorption" }, { "name":"04960 Aldosterone-regulated sodium reabsorption" }, { "name":"04961 Endocrine and other factor-regulated calcium reabsorption" }, { "name":"04964 Proximal tubule bicarbonate reclamation" }, { "name":"04966 Collecting duct acid secretion" } ] }, { "name":"09156 Nervous system", "children":[ { "name":"04724 Glutamatergic synapse" }, { "name":"04727 GABAergic synapse" }, { "name":"04725 Cholinergic synapse" }, { "name":"04728 Dopaminergic synapse" }, { "name":"04726 Serotonergic synapse" }, { "name":"04720 Long-term potentiation" }, { "name":"04730 Long-term depression" }, { "name":"04723 Retrograde endocannabinoid signaling" }, { "name":"04721 Synaptic vesicle cycle" }, { "name":"04722 Neurotrophin signaling pathway" } ] }, { "name":"09157 Sensory system", "children":[ { "name":"04744 Phototransduction" }, { "name":"04745 Phototransduction - fly" }, { "name":"04740 Olfactory transduction" }, { "name":"04742 Taste transduction" }, { "name":"04750 Inflammatory mediator regulation of TRP channels" } ] }, { "name":"09158 Development and regeneration", "children":[ { "name":"04320 Dorso-ventral axis formation" }, { "name":"04360 Axon guidance" }, { "name":"04361 Axon regeneration" }, { "name":"04380 Osteoclast differentiation" }, { "name":"04382 Cornified envelope formation" } ] }, { "name":"09149 Aging", "children":[ { "name":"04211 Longevity regulating pathway" }, { "name":"04212 Longevity regulating pathway - worm" }, { "name":"04213 Longevity regulating pathway - multiple species" } ] }, { "name":"09159 Environmental adaptation", "children":[ { "name":"04710 Circadian rhythm" }, { "name":"04713 Circadian entrainment" }, { "name":"04711 Circadian rhythm - fly" }, { "name":"04712 Circadian rhythm - plant" }, { "name":"04714 Thermogenesis" }, { "name":"04626 Plant-pathogen interaction" } ] } ] }, { "name":"09160 Human Diseases", "children":[ { "name":"09161 Cancer: overview", "children":[ { "name":"05200 Pathways in cancer" }, { "name":"05202 Transcriptional misregulation in cancer" }, { "name":"05206 MicroRNAs in cancer" }, { "name":"05205 Proteoglycans in cancer" }, { "name":"05204 Chemical carcinogenesis - DNA adducts" }, { "name":"05207 Chemical carcinogenesis - receptor activation" }, { "name":"05208 Chemical carcinogenesis - reactive oxygen species" }, { "name":"05203 Viral carcinogenesis" }, { "name":"05230 Central carbon metabolism in cancer" }, { "name":"05231 Choline metabolism in cancer" }, { "name":"05235 PD-L1 expression and PD-1 checkpoint pathway in cancer" } ] }, { "name":"09162 Cancer: specific types", "children":[ { "name":"05210 Colorectal cancer" }, { "name":"05212 Pancreatic cancer" }, { "name":"05225 Hepatocellular carcinoma" }, { "name":"05226 Gastric cancer" }, { "name":"05214 Glioma" }, { "name":"05216 Thyroid cancer" }, { "name":"05221 Acute myeloid leukemia" }, { "name":"05220 Chronic myeloid leukemia" }, { "name":"05217 Basal cell carcinoma" }, { "name":"05218 Melanoma" }, { "name":"05211 Renal cell carcinoma" }, { "name":"05219 Bladder cancer" }, { "name":"05215 Prostate cancer" }, { "name":"05213 Endometrial cancer" }, { "name":"05224 Breast cancer" }, { "name":"05222 Small cell lung cancer" }, { "name":"05223 Non-small cell lung cancer" } ] }, { "name":"09172 Infectious disease: viral", "children":[ { "name":"05166 Human T-cell leukemia virus 1 infection" }, { "name":"05170 Human immunodeficiency virus 1 infection" }, { "name":"05161 Hepatitis B" }, { "name":"05160 Hepatitis C" }, { "name":"05171 Coronavirus disease" }, { "name":"05164 Influenza A" }, { "name":"05162 Measles" }, { "name":"05168 Herpes simplex virus 1 infection" }, { "name":"05163 Human cytomegalovirus infection" }, { "name":"05167 Kaposi sarcoma-associated herpesvirus infection" }, { "name":"05169 Epstein-Barr virus infection" }, { "name":"05165 Human papillomavirus infection" } ] }, { "name":"09171 Infectious disease: bacterial", "children":[ { "name":"05110 Vibrio cholerae infection" }, { "name":"05120 Epithelial cell signaling in Helicobacter pylori infection" }, { "name":"05130 Pathogenic Escherichia coli infection" }, { "name":"05132 Salmonella infection" }, { "name":"05131 Shigellosis" }, { "name":"05135 Yersinia infection" }, { "name":"05133 Pertussis" }, { "name":"05134 Legionellosis" }, { "name":"05150 Staphylococcus aureus infection" }, { "name":"05152 Tuberculosis" }, { "name":"05100 Bacterial invasion of epithelial cells" } ] }, { "name":"09174 Infectious disease: parasitic", "children":[ { "name":"05146 Amoebiasis" }, { "name":"05144 Malaria" }, { "name":"05145 Toxoplasmosis" }, { "name":"05140 Leishmaniasis" }, { "name":"05142 Chagas disease" }, { "name":"05143 African trypanosomiasis" } ] }, { "name":"09163 Immune disease", "children":[ { "name":"05310 Asthma" }, { "name":"05322 Systemic lupus erythematosus" }, { "name":"05323 Rheumatoid arthritis" }, { "name":"05320 Autoimmune thyroid disease" }, { "name":"05321 Inflammatory bowel disease" }, { "name":"05330 Allograft rejection" }, { "name":"05332 Graft-versus-host disease" }, { "name":"05340 Primary immunodeficiency" } ] }, { "name":"09164 Neurodegenerative disease", "children":[ { "name":"05010 Alzheimer disease" }, { "name":"05012 Parkinson disease" }, { "name":"05014 Amyotrophic lateral sclerosis" }, { "name":"05016 Huntington disease" }, { "name":"05017 Spinocerebellar ataxia" }, { "name":"05020 Prion disease" }, { "name":"05022 Pathways of neurodegeneration - multiple diseases" } ] }, { "name":"09165 Substance dependence", "children":[ { "name":"05030 Cocaine addiction" }, { "name":"05031 Amphetamine addiction" }, { "name":"05032 Morphine addiction" }, { "name":"05033 Nicotine addiction" }, { "name":"05034 Alcoholism" } ] }, { "name":"09166 Cardiovascular disease", "children":[ { "name":"05417 Lipid and atherosclerosis" }, { "name":"05418 Fluid shear stress and atherosclerosis" }, { "name":"05410 Hypertrophic cardiomyopathy" }, { "name":"05412 Arrhythmogenic right ventricular cardiomyopathy" }, { "name":"05414 Dilated cardiomyopathy" }, { "name":"05415 Diabetic cardiomyopathy" }, { "name":"05416 Viral myocarditis" } ] }, { "name":"09167 Endocrine and metabolic disease", "children":[ { "name":"04930 Type II diabetes mellitus" }, { "name":"04940 Type I diabetes mellitus" }, { "name":"04950 Maturity onset diabetes of the young" }, { "name":"04936 Alcoholic liver disease" }, { "name":"04932 Non-alcoholic fatty liver disease" }, { "name":"04931 Insulin resistance" }, { "name":"04933 AGE-RAGE signaling pathway in diabetic complications" }, { "name":"04934 Cushing syndrome" } ] }, { "name":"09175 Drug resistance: antimicrobial", "children":[ { "name":"01501 beta-Lactam resistance [PATH:cvb01501]", "children":[ { "name":"R0135_16910 AmpG family muropeptide MFS transporter\tK08218 ampG; MFS transporter, PAT family, beta-lactamase induction signal transducer AmpG" }, { "name":"R0135_09930 peptide ABC transporter substrate-binding protein\tK15580 oppA; oligopeptide transport system substrate-binding protein" }, { "name":"R0135_09935 peptide ABC transporter substrate-binding protein\tK15580 oppA; oligopeptide transport system substrate-binding protein" }, { "name":"R0135_09940 ABC transporter permease subunit\tK15581 oppB; oligopeptide transport system permease protein" }, { "name":"R0135_09945 ABC transporter permease\tK15582 oppC; oligopeptide transport system permease protein" }, { "name":"R0135_01530 efflux RND transporter periplasmic adaptor subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system" }, { "name":"R0135_05670 efflux RND transporter periplasmic adaptor subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system" }, { "name":"R0135_09045 efflux RND transporter periplasmic adaptor subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system" }, { "name":"R0135_09575 efflux RND transporter periplasmic adaptor subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system" }, { "name":"R0135_12680 efflux RND transporter periplasmic adaptor subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system" }, { "name":"R0135_01525 efflux RND transporter permease subunit\tK18138 acrB; multidrug efflux pump" }, { "name":"R0135_05675 efflux RND transporter permease subunit\tK18138 acrB; multidrug efflux pump" }, { "name":"R0135_09040 efflux RND transporter permease subunit\tK18138 acrB; multidrug efflux pump" }, { "name":"R0135_09570 efflux RND transporter permease subunit\tK18138 acrB; multidrug efflux pump" }, { "name":"R0135_12685 efflux RND transporter permease subunit\tK18138 acrB; multidrug efflux pump" }, { "name":"R0135_12155 TolC family outer membrane protein\tK12340 tolC; outer membrane protein" }, { "name":"R0135_12690 penicillin-binding protein 1A\tK05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4]" }, { "name":"R0135_09320 mrdA; (GenBank) penicillin-binding protein 2\tK05515 mrdA; penicillin-binding protein 2 [EC:3.4.16.4]" }, { "name":"R0135_07245 penicillin-binding protein 2\tK03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4]" } ] }, { "name":"01502 Vancomycin resistance [PATH:cvb01502]", "children":[ { "name":"R0135_07205 D-alanine--D-alanine ligase\tK01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]" }, { "name":"R0135_01485 alr; (GenBank) alanine racemase\tK01775 alr; alanine racemase [EC:5.1.1.1]" }, { "name":"R0135_07235 murF; (GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase\tK01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10]" }, { "name":"R0135_07230 mraY; (GenBank) phospho-N-acetylmuramoyl-pentapeptide-transferase\tK01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13]" }, { "name":"R0135_07215 murG; (GenBank) undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase\tK02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227]" } ] }, { "name":"01503 Cationic antimicrobial peptide (CAMP) resistance [PATH:cvb01503]", "children":[ { "name":"R0135_14955 N-acetylmuramoyl-L-alanine amidase\tK01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]" }, { "name":"R0135_01795 Do family serine endopeptidase\tK04771 degP; serine protease Do [EC:3.4.21.107]" }, { "name":"R0135_08150 trypsin-like peptidase domain-containing protein\tK04771 degP; serine protease Do [EC:3.4.21.107]" }, { "name":"R0135_15210 Do family serine endopeptidase\tK04771 degP; serine protease Do [EC:3.4.21.107]" }, { "name":"R0135_12020 thiol:disulfide interchange protein DsbA\/DsbL\tK03673 dsbA; protein dithiol oxidoreductase (disulfide-forming) [EC:1.8.4.15]" }, { "name":"R0135_06875 peptidylprolyl isomerase\tK03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8]" }, { "name":"R0135_01530 efflux RND transporter periplasmic adaptor subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system" }, { "name":"R0135_05670 efflux RND transporter periplasmic adaptor subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system" }, { "name":"R0135_09045 efflux RND transporter periplasmic adaptor subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system" }, { "name":"R0135_09575 efflux RND transporter periplasmic adaptor subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system" }, { "name":"R0135_12680 efflux RND transporter periplasmic adaptor subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system" }, { "name":"R0135_01525 efflux RND transporter permease subunit\tK18138 acrB; multidrug efflux pump" }, { "name":"R0135_05675 efflux RND transporter permease subunit\tK18138 acrB; multidrug efflux pump" }, { "name":"R0135_09040 efflux RND transporter permease subunit\tK18138 acrB; multidrug efflux pump" }, { "name":"R0135_09570 efflux RND transporter permease subunit\tK18138 acrB; multidrug efflux pump" }, { "name":"R0135_12685 efflux RND transporter permease subunit\tK18138 acrB; multidrug efflux pump" }, { "name":"R0135_12155 TolC family outer membrane protein\tK12340 tolC; outer membrane protein" }, { "name":"R0135_00085 lpxA; (GenBank) acyl-ACP--UDP-N-acetylglucosamine O-acyltransferase\tK00677 lpxA; UDP-N-acetylglucosamine acyltransferase [EC:2.3.1.129]" } ] } ] }, { "name":"09176 Drug resistance: antineoplastic", "children":[ { "name":"01521 EGFR tyrosine kinase inhibitor resistance" }, { "name":"01524 Platinum drug resistance" }, { "name":"01523 Antifolate resistance" }, { "name":"01522 Endocrine resistance" } ] } ] }, { "name":"09180 Brite Hierarchies", "children":[ { "name":"09181 Protein families: metabolism", "children":[ { "name":"01000 Enzymes [BR:cvb01000]" }, { "name":"01001 Protein kinases [BR:cvb01001]", "children":[ { "name":"R0135_16485 PA4780 family RIO1-like protein kinase\tK07178 RIOK1; RIO kinase 1 [EC:2.7.11.1]" }, { "name":"R0135_07085 serine\/threonine-protein kinase\tK12132 prkC; eukaryotic-like serine\/threonine-protein kinase [EC:2.7.11.1]" }, { "name":"R0135_03745 polysaccharide biosynthesis tyrosine autokinase\tK16554 exoP; polysaccharide biosynthesis transport protein [EC:2.7.10.3]" }, { "name":"R0135_07790 XrtA-associated tyrosine autokinase\tK00903 epsB; protein-tyrosine kinase [EC:2.7.10.3]" }, { "name":"R0135_02195 phoR; (GenBank) phosphate regulon sensor histidine kinase PhoR\tK07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]" }, { "name":"R0135_13760 ATP-binding protein\tK07642 baeS; two-component system, OmpR family, sensor histidine kinase BaeS [EC:2.7.13.3]" }, { "name":"R0135_09660 sensor histidine kinase\tK08082 algZ; two-component system, LytTR family, sensor histidine kinase AlgZ [EC:2.7.13.3]" }, { "name":"R0135_12425 glnL; (GenBank) nitrogen regulation protein NR(II)\tK07708 glnL; two-component system, NtrC family, nitrogen regulation sensor histidine kinase GlnL [EC:2.7.13.3]" }, { "name":"R0135_17030 HAMP domain-containing sensor histidine kinase\tK02668 pilS; two-component system, NtrC family, sensor histidine kinase PilS [EC:2.7.13.3]" }, { "name":"R0135_16170 ATP-binding protein\tK10942 flrB; two-component system, sensor histidine kinase FlrB [EC:2.7.13.3]" }, { "name":"R0135_00885 PAS domain-containing sensor histidine kinase\tK20975 K20975; two-component system, sensor histidine kinase [EC:2.7.13.3]" } ] }, { "name":"01009 Protein phosphatases and associated proteins [BR:cvb01009]", "children":[ { "name":"R0135_11320 ahcY; (GenBank) adenosylhomocysteinase\tK01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1]" }, { "name":"R0135_02285 htpG; (GenBank) molecular chaperone HtpG\tK04079 HSP90A; molecular chaperone HtpG" }, { "name":"R0135_12485 serB; (GenBank) phosphoserine phosphatase SerB\tK01079 serB; phosphoserine phosphatase [EC:3.1.3.3]" } ] }, { "name":"01002 Peptidases and inhibitors [BR:cvb01002]", "children":[ { "name":"R0135_16985 lspA; (GenBank) signal peptidase II\tK03101 lspA; signal peptidase II [EC:3.4.23.36]" }, { "name":"R0135_07160 A24 family peptidase\tK02654 pilD; leader peptidase (prepilin peptidase) \/ N-methyltransferase [EC:3.4.23.43 2.1.1.-]" }, { "name":"R0135_15320 hydrogenase maturation protease\tK03605 hyaD; hydrogenase maturation protease [EC:3.4.23.-]" }, { "name":"R0135_00835 guaA; (GenBank) glutamine-hydrolyzing GMP synthase\tK01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]" }, { "name":"R0135_12450 gamma-glutamyl-gamma-aminobutyrate hydrolase family protein\tK07010 K07010; putative glutamine amidotransferase" }, { "name":"R0135_03835 purF; (GenBank) amidophosphoribosyltransferase\tK00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]" }, { "name":"R0135_12730 gltB; (GenBank) glutamate synthase large subunit\tK00265 gltB; glutamate synthase (NADPH) large chain [EC:1.4.1.13]" }, { "name":"R0135_11635 glmS; (GenBank) glutamine--fructose-6-phosphate transaminase (isomerizing)\tK00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]" }, { "name":"R0135_03775 asparagine synthase-related protein\tK01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]" }, { "name":"R0135_07715 asnB; (GenBank) asparagine synthase (glutamine-hydrolyzing)\tK01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]" }, { "name":"R0135_09910 class D sortase\tK07284 srtA; sortase A [EC:3.4.22.70]" }, { "name":"R0135_01285 type II CAAX endopeptidase family protein\tK07052 K07052; CAAX protease family protein" }, { "name":"R0135_14080 CPBP family intramembrane glutamic endopeptidase\tK07052 K07052; CAAX protease family protein" }, { "name":"R0135_04230 pepN; (GenBank) aminopeptidase N\tK01256 pepN; aminopeptidase N [EC:3.4.11.2]" }, { "name":"R0135_13605 M1 family aminopeptidase\tK01256 pepN; aminopeptidase N [EC:3.4.11.2]" }, { "name":"R0135_07995 prlC; (GenBank) oligopeptidase A\tK01414 prlC; oligopeptidase A [EC:3.4.24.70]" }, { "name":"R0135_13485 M3 family metallopeptidase\tK01284 dcp; peptidyl-dipeptidase Dcp [EC:3.4.15.5]" }, { "name":"R0135_04700 insulinase family protein\tK06972 PITRM1; presequence protease [EC:3.4.24.-]" }, { "name":"R0135_04340 insulinase family protein\tK07263 pqqL; zinc protease [EC:3.4.24.-]" }, { "name":"R0135_01625 leucyl aminopeptidase\tK01255 CARP; leucyl aminopeptidase [EC:3.4.11.1]" }, { "name":"R0135_04620 dipeptidase\tK01273 DPEP; membrane dipeptidase [EC:3.4.13.19]" }, { "name":"R0135_06690 membrane dipeptidase\tK01273 DPEP; membrane dipeptidase [EC:3.4.13.19]" }, { "name":"R0135_04185 M20\/M25\/M40 family metallo-hydrolase\tK01295 cpg; glutamate carboxypeptidase [EC:3.4.17.11]" }, { "name":"R0135_05845 M20\/M25\/M40 family metallo-hydrolase\tK01295 cpg; glutamate carboxypeptidase [EC:3.4.17.11]" }, { "name":"R0135_17560 dapE; (GenBank) succinyl-diaminopimelate desuccinylase\tK01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18]" }, { "name":"R0135_08160 M20\/M25\/M40 family metallo-hydrolase\tK13049 PM20D1; carboxypeptidase PM20D1 [EC:3.4.17.-]" }, { "name":"R0135_14730 M20 family peptidase\tK13049 PM20D1; carboxypeptidase PM20D1 [EC:3.4.17.-]" }, { "name":"R0135_04020 amidohydrolase\tK12941 abgB; aminobenzoyl-glutamate utilization protein B" }, { "name":"R0135_04315 amidohydrolase\tK12941 abgB; aminobenzoyl-glutamate utilization protein B" }, { "name":"R0135_06610 amidohydrolase\tK12941 abgB; aminobenzoyl-glutamate utilization protein B" }, { "name":"R0135_08895 amidohydrolase\tK12941 abgB; aminobenzoyl-glutamate utilization protein B" }, { "name":"R0135_00020 map; (GenBank) type I methionyl aminopeptidase\tK01265 map; methionyl aminopeptidase [EC:3.4.11.18]" }, { "name":"R0135_06975 aminopeptidase P family protein\tK01262 pepP; Xaa-Pro aminopeptidase [EC:3.4.11.9]" }, { "name":"R0135_11195 pepP; (GenBank) Xaa-Pro aminopeptidase\tK01262 pepP; Xaa-Pro aminopeptidase [EC:3.4.11.9]" }, { "name":"R0135_00310 amidohydrolase family protein\tK01305 iadA; beta-aspartyl-dipeptidase (metallo-type) [EC:3.4.19.-]" }, { "name":"R0135_08730 ftsH; (GenBank) ATP-dependent zinc metalloprotease FtsH\tK03798 ftsH; cell division protease FtsH [EC:3.4.24.-]" }, { "name":"R0135_15185 ftsH; (GenBank) ATP-dependent zinc metalloprotease FtsH\tK03798 ftsH; cell division protease FtsH [EC:3.4.24.-]" }, { "name":"R0135_06940 htpX; (GenBank) protease HtpX\tK03799 htpX; heat shock protein HtpX [EC:3.4.24.-]" }, { "name":"R0135_16730 M48 family metalloprotease\tK01423 bepA; beta-barrel assembly-enhancing protease [EC:3.4.-.-]" }, { "name":"R0135_00060 rseP; (GenBank) RIP metalloprotease RseP\tK11749 rseP; regulator of sigma E protease [EC:3.4.24.-]" }, { "name":"R0135_01795 Do family serine endopeptidase\tK04771 degP; serine protease Do [EC:3.4.21.107]" }, { "name":"R0135_08150 trypsin-like peptidase domain-containing protein\tK04771 degP; serine protease Do [EC:3.4.21.107]" }, { "name":"R0135_15210 Do family serine endopeptidase\tK04771 degP; serine protease Do [EC:3.4.21.107]" }, { "name":"R0135_07340 trypsin-like peptidase domain-containing protein\tK04691 hhoB; serine protease DegS [EC:3.4.21.-]" }, { "name":"R0135_10805 S8 family serine peptidase\tK14645 K14645; serine protease [EC:3.4.21.-]" }, { "name":"R0135_13630 prolyl oligopeptidase family serine peptidase\tK01278 DPP4; dipeptidyl-peptidase 4 [EC:3.4.14.5]" }, { "name":"R0135_13695 DPP IV N-terminal domain-containing protein\tK01278 DPP4; dipeptidyl-peptidase 4 [EC:3.4.14.5]" }, { "name":"R0135_09300 D-alanyl-D-alanine carboxypeptidase family protein\tK07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5\/6) [EC:3.4.16.4]" }, { "name":"R0135_03055 clpP; (GenBank) ATP-dependent Clp endopeptidase proteolytic subunit ClpP\tK01358 clpP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92]" }, { "name":"R0135_03045 lon; (GenBank) endopeptidase La\tK01338 lon; ATP-dependent Lon protease [EC:3.4.21.53]" }, { "name":"R0135_08365 lon; (GenBank) endopeptidase La\tK01338 lon; ATP-dependent Lon protease [EC:3.4.21.53]" }, { "name":"R0135_03520 lexA; (GenBank) transcriptional repressor LexA\tK01356 lexA; repressor LexA [EC:3.4.21.88]" }, { "name":"R0135_01805 lepB; (GenBank) signal peptidase I\tK03100 lepB; signal peptidase I [EC:3.4.21.89]" }, { "name":"R0135_08525 proline iminopeptidase-family hydrolase\tK01259 pip; proline iminopeptidase [EC:3.4.11.5]" }, { "name":"R0135_10530 alpha\/beta fold hydrolase\tK27108 ephA_B; epoxide hydrolase A\/B [EC:3.3.2.-]" }, { "name":"R0135_12095 alpha\/beta hydrolase\tK01054 MGLL; acylglycerol lipase [EC:3.1.1.23]" }, { "name":"R0135_02695 carboxy terminal-processing peptidase\tK03797 E3.4.21.102; carboxyl-terminal processing protease [EC:3.4.21.102]" }, { "name":"R0135_12385 S41 family peptidase\tK03797 E3.4.21.102; carboxyl-terminal processing protease [EC:3.4.21.102]" }, { "name":"R0135_17495 sppA; (GenBank) signal peptide peptidase SppA\tK04773 sppA; protease IV [EC:3.4.21.-]" }, { "name":"R0135_02910 sohB; (GenBank) protease SohB\tK04774 sohB; serine protease SohB [EC:3.4.21.-]" }, { "name":"R0135_04245 rhomboid family intramembrane serine protease\tK02441 glpG; rhomboid protease GlpG [EC:3.4.21.105]" }, { "name":"R0135_12645 hslV; (GenBank) ATP-dependent protease subunit HslV\tK01419 hslV; ATP-dependent HslUV protease, peptidase subunit HslV [EC:3.4.25.2]" }, { "name":"R0135_05260 gamma-glutamyltransferase\tK00681 ggt; gamma-glutamyltranspeptidase \/ glutathione hydrolase [EC:2.3.2.2 3.4.19.13]" }, { "name":"R0135_12675 ggt; (GenBank) gamma-glutamyltransferase\tK00681 ggt; gamma-glutamyltranspeptidase \/ glutathione hydrolase [EC:2.3.2.2 3.4.19.13]" }, { "name":"R0135_15070 ggt; (GenBank) gamma-glutamyltransferase\tK00681 ggt; gamma-glutamyltranspeptidase \/ glutathione hydrolase [EC:2.3.2.2 3.4.19.13]" }, { "name":"R0135_09060 TldD\/PmbA family protein\tK03568 tldD; TldD protein" }, { "name":"R0135_14985 hflC; (GenBank) protease modulator HflC\tK04087 hflC; modulator of FtsH protease HflC" }, { "name":"R0135_14980 hflK; (GenBank) FtsH protease activity modulator HflK\tK04088 hflK; modulator of FtsH protease HflK" } ] }, { "name":"01003 Glycosyltransferases [BR:cvb01003]", "children":[ { "name":"R0135_07695 glycosyltransferase family 4 protein\tK13668 pimB; phosphatidyl-myo-inositol dimannoside synthase [EC:2.4.1.346]" }, { "name":"R0135_14620 mrcB; (GenBank) penicillin-binding protein 1B\tK05365 mrcB; penicillin-binding protein 1B [EC:2.4.99.28 3.4.16.4]" }, { "name":"R0135_12690 penicillin-binding protein 1A\tK05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4]" }, { "name":"R0135_07220 ftsW; (GenBank) putative lipid II flippase FtsW\tK03588 ftsW; peptidoglycan glycosyltransferase [EC:2.4.99.28]" }, { "name":"R0135_09315 rodA; (GenBank) rod shape-determining protein RodA\tK05837 rodA; peptidoglycan glycosyltransferase [EC:2.4.99.28]" }, { "name":"R0135_03755 hypothetical protein\tK02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate\/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35]" }, { "name":"R0135_11795 glycoside hydrolase family 68 protein\tK00692 sacB; levansucrase [EC:2.4.1.10]" }, { "name":"R0135_15205 glucoamylase family protein\tK13688 chvB; cyclic beta-1,2-glucan glucanotransferase [EC:2.4.1.397]" }, { "name":"R0135_12130 glycosyltransferase family 4 protein\tK26815 manT; MMP alpha-(1->4)-mannosyltransferase [EC:2.4.1.393]" }, { "name":"R0135_16770 glycosyl transferase\tK13693 gpgS; glucosyl-3-phosphoglycerate synthase [EC:2.4.1.266]" } ] }, { "name":"01005 Lipopolysaccharide biosynthesis proteins [BR:cvb01005]", "children":[ { "name":"R0135_00085 lpxA; (GenBank) acyl-ACP--UDP-N-acetylglucosamine O-acyltransferase\tK00677 lpxA; UDP-N-acetylglucosamine acyltransferase [EC:2.3.1.129]" }, { "name":"R0135_00090 lpxB; (GenBank) lipid-A-disaccharide synthase\tK00748 lpxB; lipid-A-disaccharide synthase [EC:2.4.1.182]" }, { "name":"R0135_07185 lpxC; (GenBank) UDP-3-O-acyl-N-acetylglucosamine deacetylase\tK02535 lpxC; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [EC:3.5.1.108]" }, { "name":"R0135_00075 lpxD; (GenBank) UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase\tK02536 lpxD; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase [EC:2.3.1.191]" }, { "name":"R0135_03655 UDP-2,3-diacylglucosamine diphosphatase\tK03269 lpxH; UDP-2,3-diacylglucosamine hydrolase [EC:3.6.1.54]" }, { "name":"R0135_03410 lpxK; (GenBank) tetraacyldisaccharide 4'-kinase\tK00912 lpxK; tetraacyldisaccharide 4'-kinase [EC:2.7.1.130]" }, { "name":"R0135_11840 lysophospholipid acyltransferase family protein\tK02517 lpxL; Kdo2-lipid IVA lauroyltransferase\/acyltransferase [EC:2.3.1.241 2.3.1.-]" }, { "name":"R0135_13050 lysophospholipid acyltransferase family protein\tK02517 lpxL; Kdo2-lipid IVA lauroyltransferase\/acyltransferase [EC:2.3.1.241 2.3.1.-]" }, { "name":"R0135_12150 waaA; (GenBank) lipid IV(A) 3-deoxy-D-manno-octulosonic acid transferase\tK02527 kdtA; 3-deoxy-D-manno-octulosonic-acid transferase [EC:2.4.99.12 2.4.99.13 2.4.99.14 2.4.99.15]" }, { "name":"R0135_05395 kdsA; (GenBank) 3-deoxy-8-phosphooctulonate synthase\tK01627 kdsA; 2-dehydro-3-deoxyphosphooctonate aldolase (KDO 8-P synthase) [EC:2.5.1.55]" }, { "name":"R0135_03405 kdsB; (GenBank) 3-deoxy-manno-octulosonate cytidylyltransferase\tK00979 kdsB; 3-deoxy-manno-octulosonate cytidylyltransferase (CMP-KDO synthetase) [EC:2.7.7.38]" }, { "name":"R0135_07380 HAD-IIIA family hydrolase\tK03270 kdsC; 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (KDO 8-P phosphatase) [EC:3.1.3.45]" }, { "name":"R0135_07375 KpsF\/GutQ family sugar-phosphate isomerase\tK06041 kdsD; arabinose-5-phosphate isomerase [EC:5.3.1.13]" }, { "name":"R0135_07285 phosphoheptose isomerase\tK03271 gmhA; D-sedoheptulose 7-phosphate isomerase [EC:5.3.1.28]" }, { "name":"R0135_06750 glycosyltransferase family 4 protein\tK13007 wbpL; glycosyltransferase WbpL [EC:2.4.1.-]" }, { "name":"R0135_15505 glycosyltransferase family 2 protein\tK12990 rfbF; rhamnosyltransferase [EC:2.4.1.-]" }, { "name":"R0135_10695 glycosyltransferase family 2 protein\tK20534 gtrB; polyisoprenyl-phosphate glycosyltransferase [EC:2.4.-.-]" }, { "name":"R0135_03755 hypothetical protein\tK02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate\/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35]" } ] }, { "name":"01011 Peptidoglycan biosynthesis and degradation proteins [BR:cvb01011]", "children":[ { "name":"R0135_07355 murA; (GenBank) UDP-N-acetylglucosamine 1-carboxyvinyltransferase\tK00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7]" }, { "name":"R0135_03400 murB; (GenBank) UDP-N-acetylmuramate dehydrogenase\tK00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98]" }, { "name":"R0135_07210 murC; (GenBank) UDP-N-acetylmuramate--L-alanine ligase\tK01924 murC; UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8]" }, { "name":"R0135_07225 murD; (GenBank) UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase\tK01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9]" }, { "name":"R0135_07240 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase\tK01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13]" }, { "name":"R0135_07205 D-alanine--D-alanine ligase\tK01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]" }, { "name":"R0135_01485 alr; (GenBank) alanine racemase\tK01775 alr; alanine racemase [EC:5.1.1.1]" }, { "name":"R0135_07230 mraY; (GenBank) phospho-N-acetylmuramoyl-pentapeptide-transferase\tK01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13]" }, { "name":"R0135_07215 murG; (GenBank) undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase\tK02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227]" }, { "name":"R0135_01865 undecaprenyl-diphosphate phosphatase\tK06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27]" }, { "name":"R0135_16970 murJ; (GenBank) murein biosynthesis integral membrane protein MurJ\tK03980 murJ; putative peptidoglycan lipid II flippase" }, { "name":"R0135_12690 penicillin-binding protein 1A\tK05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4]" }, { "name":"R0135_14620 mrcB; (GenBank) penicillin-binding protein 1B\tK05365 mrcB; penicillin-binding protein 1B [EC:2.4.99.28 3.4.16.4]" }, { "name":"R0135_09320 mrdA; (GenBank) penicillin-binding protein 2\tK05515 mrdA; penicillin-binding protein 2 [EC:3.4.16.4]" }, { "name":"R0135_07245 penicillin-binding protein 2\tK03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4]" }, { "name":"R0135_09300 D-alanyl-D-alanine carboxypeptidase family protein\tK07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5\/6) [EC:3.4.16.4]" }, { "name":"R0135_07220 ftsW; (GenBank) putative lipid II flippase FtsW\tK03588 ftsW; peptidoglycan glycosyltransferase [EC:2.4.99.28]" }, { "name":"R0135_09315 rodA; (GenBank) rod shape-determining protein RodA\tK05837 rodA; peptidoglycan glycosyltransferase [EC:2.4.99.28]" }, { "name":"R0135_09910 class D sortase\tK07284 srtA; sortase A [EC:3.4.22.70]" }, { "name":"R0135_04055 transglycosylase SLT domain-containing protein\tK08309 slt; peptidoglycan lytic transglycosylase [EC:4.2.2.29]" }, { "name":"R0135_02390 lytic murein transglycosylase\tK08305 mltB; peptidoglycan lytic transglycosylase B [EC:4.2.2.29]" }, { "name":"R0135_09310 mltB; (GenBank) lytic murein transglycosylase B\tK08305 mltB; peptidoglycan lytic transglycosylase B [EC:4.2.2.29]" }, { "name":"R0135_02405 murein transglycosylase domain-containing protein\tK08306 mltC; peptidoglycan lytic transglycosylase C [EC:4.2.2.29]" }, { "name":"R0135_02945 LysM peptidoglycan-binding domain-containing protein\tK08307 mltD; peptidoglycan lytic transglycosylase D [EC:4.2.2.29]" }, { "name":"R0135_00930 mltF; (GenBank) membrane-bound lytic murein transglycosylase MltF\tK18691 mltF; peptidoglycan lytic transglycosylase F [EC:4.2.2.29]" }, { "name":"R0135_03090 mltG; (GenBank) endolytic transglycosylase MltG\tK07082 mltG; peptidoglycan lytic transglycosylase G [EC:4.2.2.29]" }, { "name":"R0135_09305 septal ring lytic transglycosylase RlpA family protein\tK03642 rlpA; peptidoglycan lytic transglycosylase [EC:4.2.2.29]" }, { "name":"R0135_14955 N-acetylmuramoyl-L-alanine amidase\tK01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]" }, { "name":"R0135_07100 ampD; (GenBank) 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD\tK03806 ampD; N-acetyl-anhydromuramoyl-L-alanine amidase [EC:3.5.1.28]" } ] }, { "name":"01004 Lipid biosynthesis proteins [BR:cvb01004]", "children":[ { "name":"R0135_03115 fabD; (GenBank) ACP S-malonyltransferase\tK00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]" }, { "name":"R0135_04425 beta-ketoacyl synthase\tK18473 fabY; acetoacetyl-[acyl-carrier protein] synthase [EC:2.3.1.180]" }, { "name":"R0135_15900 fabB; (GenBank) beta-ketoacyl-ACP synthase I\tK00647 fabB; 3-oxoacyl-[acyl-carrier-protein] synthase I [EC:2.3.1.41]" }, { "name":"R0135_03100 fabF; (GenBank) beta-ketoacyl-ACP synthase II\tK09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179]" }, { "name":"R0135_03110 fabG; (GenBank) 3-oxoacyl-ACP reductase FabG\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]" }, { "name":"R0135_04290 SDR family oxidoreductase\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]" }, { "name":"R0135_08120 SDR family oxidoreductase\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]" }, { "name":"R0135_10580 SDR family oxidoreductase\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]" }, { "name":"R0135_15905 fabA; (GenBank) 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabA\tK01716 fabA; 3-hydroxyacyl-[acyl-carrier protein] dehydratase \/ trans-2-decenoyl-[acyl-carrier protein] isomerase [EC:4.2.1.59 5.3.3.14]" }, { "name":"R0135_00080 fabZ; (GenBank) 3-hydroxyacyl-ACP dehydratase FabZ\tK02372 fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:4.2.1.59]" }, { "name":"R0135_05290 nitronate monooxygenase\tK02371 fabK; enoyl-[acyl-carrier protein] reductase II [EC:1.3.1.9]" }, { "name":"R0135_16780 trans-2-enoyl-CoA reductase family protein\tK00209 fabV; enoyl-[acyl-carrier protein] reductase \/ trans-2-enoyl-CoA reductase (NAD+) [EC:1.3.1.9 1.3.1.44]" }, { "name":"R0135_08515 PaaI family thioesterase\tK17362 ACOT13; acyl-coenzyme A thioesterase 13 [EC:3.1.2.-]" }, { "name":"R0135_02095 arylesterase\tK10804 tesA; acyl-CoA thioesterase I [EC:3.1.2.- 3.1.2.2 3.1.1.2 3.1.1.5]" }, { "name":"R0135_16680 acyl-CoA thioesterase II\tK10805 tesB; acyl-CoA thioesterase II [EC:3.1.2.20]" }, { "name":"R0135_11595 acyl-CoA thioesterase\tK10806 yciA; acyl-CoA thioesterase [EC:3.1.2.-]" }, { "name":"R0135_09275 fatty acid desaturase\tK00507 SCD; stearoyl-CoA desaturase (Delta-9 desaturase) [EC:1.14.19.1]" }, { "name":"R0135_08655 acs; (GenBank) acetate--CoA ligase\tK01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]" }, { "name":"R0135_04160 propionyl-CoA synthetase\tK01908 ACSS3; propionyl-CoA synthetase [EC:6.2.1.17]" }, { "name":"R0135_05490 AMP-binding protein\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]" }, { "name":"R0135_05640 AMP-binding protein\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]" }, { "name":"R0135_10175 glycerol-3-phosphate 1-O-acyltransferase\tK00631 plsB; glycerol-3-phosphate O-acyltransferase [EC:2.3.1.15]" }, { "name":"R0135_03990 lysophospholipid acyltransferase family protein\tK00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]" } ] }, { "name":"01008 Polyketide biosynthesis proteins [BR:cvb01008]", "children":[ { "name":"R0135_04080 amino acid racemase\tK01779 racD; aspartate racemase [EC:5.1.1.13]" } ] }, { "name":"01006 Prenyltransferases [BR:cvb01006]", "children":[ { "name":"R0135_15485 polyprenyl synthetase family protein\tK00795 ispA; farnesyl diphosphate synthase [EC:2.5.1.1 2.5.1.10]" }, { "name":"R0135_17175 polyprenyl synthetase family protein\tK13789 GGPS; geranylgeranyl diphosphate synthase, type II [EC:2.5.1.1 2.5.1.10 2.5.1.29]" }, { "name":"R0135_15925 polyprenyl synthetase family protein\tK02523 ispB; octaprenyl-diphosphate synthase [EC:2.5.1.90]" }, { "name":"R0135_00045 uppS; (GenBank) polyprenyl diphosphate synthase\tK00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31]" }, { "name":"R0135_17165 phytoene\/squalene synthase family protein\tK02291 crtB; 15-cis-phytoene synthase [EC:2.5.1.32]" }, { "name":"R0135_14965 miaA; (GenBank) tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA\tK00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]" }, { "name":"R0135_04575 prenyltransferase\tK02548 menA; 1,4-dihydroxy-2-naphthoate polyprenyltransferase [EC:2.5.1.74]" }, { "name":"R0135_14070 prenyltransferase\tK02548 menA; 1,4-dihydroxy-2-naphthoate polyprenyltransferase [EC:2.5.1.74]" }, { "name":"R0135_11555 ubiA; (GenBank) 4-hydroxybenzoate octaprenyltransferase\tK03179 ubiA; 4-hydroxybenzoate polyprenyltransferase [EC:2.5.1.39]" }, { "name":"R0135_11985 cyoE; (GenBank) heme o synthase\tK02257 COX10; heme o synthase [EC:2.5.1.141]" }, { "name":"R0135_17305 chlG; (GenBank) chlorophyll synthase ChlG\tK04040 chlG; chlorophyll\/bacteriochlorophyll a synthase [EC:2.5.1.62 2.5.1.133]" } ] }, { "name":"01007 Amino acid related enzymes [BR:cvb01007]", "children":[ { "name":"R0135_04595 gltX; (GenBank) glutamate--tRNA ligase\tK01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]" }, { "name":"R0135_03645 glutamine--tRNA ligase\/YqeY domain fusion protein\tK01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18]" }, { "name":"R0135_08615 gluQRS; (GenBank) tRNA glutamyl-Q(34) synthetase GluQRS\tK01894 gluQ; glutamyl-Q tRNA(Asp) synthetase [EC:6.1.1.-]" }, { "name":"R0135_14685 tyrS; (GenBank) tyrosine--tRNA ligase\tK01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]" }, { "name":"R0135_01880 trpS; (GenBank) tryptophan--tRNA ligase\tK01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]" }, { "name":"R0135_03640 cysS; (GenBank) cysteine--tRNA ligase\tK01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]" }, { "name":"R0135_12655 argS; (GenBank) arginine--tRNA ligase\tK01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]" }, { "name":"R0135_17395 metG; (GenBank) methionine--tRNA ligase\tK01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]" }, { "name":"R0135_16980 ileS; (GenBank) isoleucine--tRNA ligase\tK01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]" }, { "name":"R0135_01615 valine--tRNA ligase\tK01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]" }, { "name":"R0135_08400 leuS; (GenBank) leucine--tRNA ligase\tK01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]" }, { "name":"R0135_00795 lysS; (GenBank) lysine--tRNA ligase\tK04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]" }, { "name":"R0135_09230 aspS; (GenBank) aspartate--tRNA ligase\tK01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]" }, { "name":"R0135_14910 asnS; (GenBank) asparagine--tRNA ligase\tK01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]" }, { "name":"R0135_00985 hisS; (GenBank) histidine--tRNA ligase\tK01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]" }, { "name":"R0135_11835 glyQ; (GenBank) glycine--tRNA ligase subunit alpha\tK01878 glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14]" }, { "name":"R0135_11830 glyS; (GenBank) glycine--tRNA ligase subunit beta\tK01879 glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14]" }, { "name":"R0135_02680 serS; (GenBank) serine--tRNA ligase\tK01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]" }, { "name":"R0135_09245 proline--tRNA ligase\tK01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]" }, { "name":"R0135_06095 thrS; (GenBank) threonine--tRNA ligase\tK01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]" }, { "name":"R0135_00200 alaS; (GenBank) alanine--tRNA ligase\tK01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]" }, { "name":"R0135_06075 pheS; (GenBank) phenylalanine--tRNA ligase subunit alpha\tK01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]" }, { "name":"R0135_06070 pheT; (GenBank) phenylalanine--tRNA ligase subunit beta\tK01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]" }, { "name":"R0135_08335 amino acid aminotransferase\tK00813 aspC; aspartate aminotransferase [EC:2.6.1.1]" }, { "name":"R0135_04025 valine--pyruvate transaminase\tK00835 avtA; valine--pyruvate aminotransferase [EC:2.6.1.66]" }, { "name":"R0135_00770 alaC; (GenBank) alanine transaminase\tK14261 alaC; alanine-synthesizing transaminase [EC:2.6.1.-]" }, { "name":"R0135_05015 methionine aminotransferase\tK14287 ybdL; methionine transaminase [EC:2.6.1.88]" }, { "name":"R0135_06955 pyridoxal phosphate-dependent aminotransferase\tK12252 aruH; arginine:pyruvate transaminase [EC:2.6.1.84]" }, { "name":"R0135_00010 dapC; (GenBank) succinyldiaminopimelate transaminase\tK14267 dapC; N-succinyldiaminopimelate aminotransferase [EC:2.6.1.17]" }, { "name":"R0135_02225 hisC; (GenBank) histidinol-phosphate transaminase\tK00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]" }, { "name":"R0135_03320 histidinol-phosphate transaminase\tK00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]" }, { "name":"R0135_05610 glycine C-acetyltransferase\tK00639 kbl; glycine C-acetyltransferase [EC:2.3.1.29]" }, { "name":"R0135_08990 aspartate aminotransferase family protein\tK00822 E2.6.1.18; beta-alanine--pyruvate transaminase [EC:2.6.1.18]" }, { "name":"R0135_09360 aspartate aminotransferase family protein\tK00821 argD; acetylornithine\/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17]" }, { "name":"R0135_10765 aminotransferase\tK12256 spuC; putrescine---pyruvate transaminase [EC:2.6.1.113]" }, { "name":"R0135_14650 hemL; (GenBank) glutamate-1-semialdehyde 2,1-aminomutase\tK01845 hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8]" }, { "name":"R0135_01490 aminotransferase class IV\tK00824 dat; D-alanine transaminase [EC:2.6.1.21]" }, { "name":"R0135_08350 aminotransferase class IV\tK00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]" }, { "name":"R0135_12090 branched-chain amino acid transaminase\tK00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]" }, { "name":"R0135_03940 alanine--glyoxylate aminotransferase family protein\tK00830 AGXT; alanine-glyoxylate transaminase \/ serine-glyoxylate transaminase \/ serine-pyruvate transaminase [EC:2.6.1.44 2.6.1.45 2.6.1.51]" }, { "name":"R0135_06810 serC; (GenBank) 3-phosphoserine\/phosphohydroxythreonine transaminase\tK00831 serC; phosphoserine aminotransferase [EC:2.6.1.52]" } ] }, { "name":"00199 Cytochrome P450" }, { "name":"00194 Photosynthesis proteins [BR:cvb00194]", "children":[ { "name":"R0135_11655 F0F1 ATP synthase subunit epsilon\tK02114 ATPF1E; F-type H+-transporting ATPase subunit epsilon" }, { "name":"R0135_15255 F0F1 ATP synthase subunit epsilon\tK02114 ATPF1E; F-type H+-transporting ATPase subunit epsilon" }, { "name":"R0135_11660 atpD; (GenBank) F0F1 ATP synthase subunit beta\tK02112 ATPF1B; F-type H+\/Na+-transporting ATPase subunit beta [EC:7.1.2.2 7.2.2.1]" }, { "name":"R0135_15250 atpD; (GenBank) F0F1 ATP synthase subunit beta\tK02112 ATPF1B; F-type H+\/Na+-transporting ATPase subunit beta [EC:7.1.2.2 7.2.2.1]" }, { "name":"R0135_11665 atpG; (GenBank) F0F1 ATP synthase subunit gamma\tK02115 ATPF1G; F-type H+-transporting ATPase subunit gamma" }, { "name":"R0135_15290 F0F1 ATP synthase subunit gamma\tK02115 ATPF1G; F-type H+-transporting ATPase subunit gamma" }, { "name":"R0135_11670 atpA; (GenBank) F0F1 ATP synthase subunit alpha\tK02111 ATPF1A; F-type H+\/Na+-transporting ATPase subunit alpha [EC:7.1.2.2 7.2.2.1]" }, { "name":"R0135_15285 alternate F1F0 ATPase, F1 subunit alpha\tK02111 ATPF1A; F-type H+\/Na+-transporting ATPase subunit alpha [EC:7.1.2.2 7.2.2.1]" }, { "name":"R0135_11675 F0F1 ATP synthase subunit delta\tK02113 ATPF1D; F-type H+-transporting ATPase subunit delta" }, { "name":"R0135_11680 F0F1 ATP synthase subunit B\tK02109 ATPF0B; F-type H+-transporting ATPase subunit b" }, { "name":"R0135_15280 hypothetical protein\tK02109 ATPF0B; F-type H+-transporting ATPase subunit b" }, { "name":"R0135_11685 atpE; (GenBank) F0F1 ATP synthase subunit C\tK02110 ATPF0C; F-type H+-transporting ATPase subunit c" }, { "name":"R0135_15275 F0F1 ATP synthase subunit C\tK02110 ATPF0C; F-type H+-transporting ATPase subunit c" }, { "name":"R0135_11690 atpB; (GenBank) F0F1 ATP synthase subunit A\tK02108 ATPF0A; F-type H+-transporting ATPase subunit a" }, { "name":"R0135_15270 F0F1 ATP synthase subunit A\tK02108 ATPF0A; F-type H+-transporting ATPase subunit a" }, { "name":"R0135_11695 ATP synthase subunit I\tK02116 atpI; ATP synthase protein I" }, { "name":"R0135_15260 AtpZ\/AtpI family protein\tK02116 atpI; ATP synthase protein I" }, { "name":"R0135_17210 pufL; (GenBank) photosynthetic reaction center subunit L\tK08928 pufL; photosynthetic reaction center L subunit" }, { "name":"R0135_17215 pufM; (GenBank) photosynthetic reaction center subunit M\tK08929 pufM; photosynthetic reaction center M subunit" }, { "name":"R0135_17260 puhA; (GenBank) photosynthetic reaction center subunit H\tK13991 puhA; photosynthetic reaction center H subunit" }, { "name":"R0135_17230 pufA; (GenBank) light-harvesting antenna LH1, alpha subunit\tK08926 pufA; light-harvesting complex 1 alpha chain" }, { "name":"R0135_17225 pufB; (GenBank) light-harvesting antenna LH1, beta subunit\tK08927 pufB; light-harvesting complex 1 beta chain" }, { "name":"R0135_13335 light-harvesting protein\tK08930 pucA; light-harvesting protein B-800-850 alpha chain" }, { "name":"R0135_13340 pufB; (GenBank) light-harvesting antenna LH1, beta subunit\tK08939 pucB; light-harvesting protein B-800-850 beta chain" } ] } ] }, { "name":"09182 Protein families: genetic information processing", "children":[ { "name":"03000 Transcription factors [BR:cvb03000]", "children":[ { "name":"R0135_14175 DNA cytosine methyltransferase\tK00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]" }, { "name":"R0135_06005 methylated-DNA--[protein]-cysteine S-methyltransferase\tK10778 ada; AraC family transcriptional regulator, regulatory protein of adaptative response \/ methylated-DNA-[protein]-cysteine methyltransferase [EC:2.1.1.63]" }, { "name":"R0135_06445 LysR substrate-binding domain-containing protein\tK03566 gcvA; LysR family transcriptional regulator, glycine cleavage system transcriptional activator" }, { "name":"R0135_17080 ilvY; (GenBank) HTH-type transcriptional activator IlvY\tK02521 ilvY; LysR family transcriptional regulator, positive regulator for ilvC" }, { "name":"R0135_04795 LysR family transcriptional regulator\tK03717 nhaR; LysR family transcriptional regulator, transcriptional activator of nhaA" }, { "name":"R0135_02085 hydrogen peroxide-inducible genes activator\tK04761 oxyR; LysR family transcriptional regulator, hydrogen peroxide-inducible genes activator" }, { "name":"R0135_11815 hydrogen peroxide-inducible genes activator\tK04761 oxyR; LysR family transcriptional regulator, hydrogen peroxide-inducible genes activator" }, { "name":"R0135_12850 hydrogen peroxide-inducible genes activator\tK04761 oxyR; LysR family transcriptional regulator, hydrogen peroxide-inducible genes activator" }, { "name":"R0135_02545 cysB; (GenBank) HTH-type transcriptional regulator CysB\tK13634 cysB; LysR family transcriptional regulator, cys regulon transcriptional activator" }, { "name":"R0135_08325 LysR substrate-binding domain-containing protein\tK17737 dhcR; LysR family transcriptional regulator, carnitine catabolism transcriptional activator" }, { "name":"R0135_10620 LacI family DNA-binding transcriptional regulator\tK02529 galR; LacI family transcriptional regulator, galactose operon repressor" }, { "name":"R0135_11485 slmA; (GenBank) nucleoid occlusion factor SlmA\tK05501 slmA; TetR\/AcrR family transcriptional regulator" }, { "name":"R0135_04805 Lrp\/AsnC family transcriptional regulator\tK03719 lrp; Lrp\/AsnC family transcriptional regulator, leucine-responsive regulatory protein" }, { "name":"R0135_12040 Lrp\/AsnC family transcriptional regulator\tK03719 lrp; Lrp\/AsnC family transcriptional regulator, leucine-responsive regulatory protein" }, { "name":"R0135_10925 Lrp\/AsnC family transcriptional regulator\tK05800 decR; Lrp\/AsnC family transcriptional regulator, cysteine-sensing transcriptional activator" }, { "name":"R0135_17440 Lrp\/AsnC family transcriptional regulator\tK05800 decR; Lrp\/AsnC family transcriptional regulator, cysteine-sensing transcriptional activator" }, { "name":"R0135_16610 fur; (GenBank) ferric iron uptake transcriptional regulator\tK03711 fur; Fur family transcriptional regulator, ferric uptake regulator" }, { "name":"R0135_09080 IclR family transcriptional regulator\tK19333 kdgR; IclR family transcriptional regulator, KDG regulon repressor" }, { "name":"R0135_00820 Crp\/Fnr family transcriptional regulator\tK10914 crp; CRP\/FNR family transcriptional regulator, cyclic AMP receptor protein" }, { "name":"R0135_05940 Crp\/Fnr family transcriptional regulator\tK10914 crp; CRP\/FNR family transcriptional regulator, cyclic AMP receptor protein" }, { "name":"R0135_14540 crp; (GenBank) cAMP-activated global transcriptional regulator CRP\tK10914 crp; CRP\/FNR family transcriptional regulator, cyclic AMP receptor protein" }, { "name":"R0135_01735 fnr; (GenBank) fumarate\/nitrate reduction transcriptional regulator Fnr\tK01420 fnr; CRP\/FNR family transcriptional regulator, anaerobic regulatory protein" }, { "name":"R0135_10020 iscR; (GenBank) Fe-S cluster assembly transcriptional regulator IscR\tK13643 iscR; Rrf2 family transcriptional regulator, iron-sulfur cluster assembly transcription factor" }, { "name":"R0135_06115 Rrf2 family transcriptional regulator\tK13771 nsrR; Rrf2 family transcriptional regulator, nitric oxide-sensitive transcriptional repressor" }, { "name":"R0135_12945 metalloregulator ArsR\/SmtB family transcription factor\tK22042 hlyU; ArsR family transcriptional regulator, virulence genes transcriptional regulator" }, { "name":"R0135_05165 hexR; (GenBank) transcriptional regulator HexR\tK19337 hexR; RpiR family transcriptional regulator, carbohydrate utilization regulator" }, { "name":"R0135_15600 birA; (GenBank) bifunctional biotin--[acetyl-CoA-carboxylase] ligase\/biotin operon repressor BirA\tK03524 birA; BirA family transcriptional regulator, biotin operon repressor \/ biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]" }, { "name":"R0135_14565 fis; (GenBank) DNA-binding transcriptional regulator Fis\tK03557 fis; Fis family transcriptional regulator, factor for inversion stimulation protein" }, { "name":"R0135_00150 sigma 54-interacting transcriptional regulator\tK02688 prpR; transcriptional regulator, propionate catabolism operon regulatory protein" }, { "name":"R0135_13650 putA; (GenBank) bifunctional proline dehydrogenase\/L-glutamate gamma-semialdehyde dehydrogenase PutA\tK13821 putA; RHH-type transcriptional regulator, proline utilization regulon repressor \/ proline dehydrogenase \/ delta 1-pyrroline-5-carboxylate dehydrogenase [EC:1.5.5.2 1.2.1.88]" }, { "name":"R0135_01650 BolA\/IbaG family iron-sulfur metabolism protein\tK05527 bolA; BolA family transcriptional regulator, general stress-responsive regulator" }, { "name":"R0135_11700 ParB\/RepB\/Spo0J family partition protein\tK03497 parB; ParB family transcriptional regulator, chromosome partitioning protein" }, { "name":"R0135_03690 transcription termination\/antitermination NusG family protein\tK05785 rfaH; transcriptional antiterminator RfaH" }, { "name":"R0135_16620 hrcA; (GenBank) heat-inducible transcriptional repressor HrcA\tK03705 hrcA; heat-inducible transcriptional repressor" }, { "name":"R0135_13195 PaaX\tK02616 paaX; phenylacetic acid degradation operon negative regulatory protein" }, { "name":"R0135_01970 pspF; (GenBank) phage shock protein operon transcriptional activator\tK03974 pspF; psp operon transcriptional activator" }, { "name":"R0135_11345 YqgE\/AlgH family protein\tK07735 algH; putative transcriptional regulator" }, { "name":"R0135_08610 dksA; (GenBank) RNA polymerase-binding protein DksA\tK06204 dksA; RNA polymerase-binding transcription factor" }, { "name":"R0135_15435 nrdR; (GenBank) transcriptional regulator NrdR\tK07738 nrdR; transcriptional repressor NrdR" }, { "name":"R0135_07260 mraZ; (GenBank) division\/cell wall cluster transcriptional repressor MraZ\tK03925 mraZ; transcriptional regulator MraZ" } ] }, { "name":"03021 Transcription machinery [BR:cvb03021]", "children":[ { "name":"R0135_15860 rpoA; (GenBank) DNA-directed RNA polymerase subunit alpha\tK03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]" }, { "name":"R0135_15680 rpoB; (GenBank) DNA-directed RNA polymerase subunit beta\tK03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]" }, { "name":"R0135_15685 rpoC; (GenBank) DNA-directed RNA polymerase subunit beta'\tK03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]" }, { "name":"R0135_11520 rpoZ; (GenBank) DNA-directed RNA polymerase subunit omega\tK03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]" }, { "name":"R0135_14325 rpoD; (GenBank) RNA polymerase sigma factor RpoD\tK03086 rpoD; RNA polymerase primary sigma factor" }, { "name":"R0135_03270 sigma-70 family RNA polymerase sigma factor\tK03087 rpoS; RNA polymerase nonessential primary-like sigma factor" }, { "name":"R0135_05355 rpoS; (GenBank) RNA polymerase sigma factor RpoS\tK03087 rpoS; RNA polymerase nonessential primary-like sigma factor" }, { "name":"R0135_01775 rpoE; (GenBank) RNA polymerase sigma factor RpoE\tK03088 rpoE; RNA polymerase sigma-70 factor, ECF subfamily" }, { "name":"R0135_09900 sigma-70 family RNA polymerase sigma factor\tK03088 rpoE; RNA polymerase sigma-70 factor, ECF subfamily" }, { "name":"R0135_12535 sigma-70 family RNA polymerase sigma factor\tK03088 rpoE; RNA polymerase sigma-70 factor, ECF subfamily" }, { "name":"R0135_11415 rpoH; (GenBank) RNA polymerase sigma factor RpoH\tK03089 rpoH; RNA polymerase sigma-32 factor" }, { "name":"R0135_07400 RNA polymerase factor sigma-54\tK03092 rpoN; RNA polymerase sigma-54 factor" }, { "name":"R0135_16270 RNA polymerase sigma factor FliA\tK02405 fliA; RNA polymerase sigma factor FliA" }, { "name":"R0135_01585 rapA; (GenBank) RNA polymerase-associated protein RapA\tK03580 hepA; ATP-dependent helicase HepA [EC:5.6.2.-]" }, { "name":"R0135_08690 nusA; (GenBank) transcription termination factor NusA\tK02600 nusA; transcription termination\/antitermination protein NusA" }, { "name":"R0135_15460 nusB; (GenBank) transcription antitermination factor NusB\tK03625 nusB; transcription antitermination protein NusB" }, { "name":"R0135_15655 nusG; (GenBank) transcription termination\/antitermination protein NusG\tK02601 nusG; transcription termination\/antitermination protein NusG" }, { "name":"R0135_07300 glutathione S-transferase N-terminal domain-containing protein\tK03599 sspA; stringent starvation protein A" }, { "name":"R0135_07295 ClpXP protease specificity-enhancing factor\tK03600 sspB; stringent starvation protein B" }, { "name":"R0135_01780 sigma-E factor negative regulatory protein\tK03597 rseA; sigma-E factor negative regulatory protein RseA" }, { "name":"R0135_01785 MucB\/RseB C-terminal domain-containing protein\tK03598 rseB; sigma-E factor negative regulatory protein RseB" }, { "name":"R0135_01790 SoxR reducing system RseC family protein\tK03803 rseC; sigma-E factor negative regulatory protein RseC" }, { "name":"R0135_08610 dksA; (GenBank) RNA polymerase-binding protein DksA\tK06204 dksA; RNA polymerase-binding transcription factor" }, { "name":"R0135_08745 greA; (GenBank) transcription elongation factor GreA\tK03624 greA; transcription elongation factor GreA" }, { "name":"R0135_00175 greB; (GenBank) transcription elongation factor GreB\tK04760 greB; transcription elongation factor GreB" }, { "name":"R0135_09625 rho; (GenBank) transcription termination factor Rho\tK03628 rho; transcription termination factor Rho" } ] }, { "name":"03019 Messenger RNA biogenesis [BR:cvb03019]", "children":[ { "name":"R0135_03140 rne; (GenBank) ribonuclease E\tK08300 rne; ribonuclease E [EC:3.1.26.12]" }, { "name":"R0135_07440 rng; (GenBank) ribonuclease G\tK08301 rng; ribonuclease G [EC:3.1.26.-]" }, { "name":"R0135_01815 rnc; (GenBank) ribonuclease III\tK03685 rnc; ribonuclease III [EC:3.1.26.3]" }, { "name":"R0135_10840 ribonuclease J\tK12574 rnj; ribonuclease J [EC:3.1.-.-]" }, { "name":"R0135_15360 rnr; (GenBank) ribonuclease R\tK12573 rnr; ribonuclease R [EC:3.1.13.1]" }, { "name":"R0135_14935 orn; (GenBank) oligoribonuclease\tK13288 orn; oligoribonuclease [EC:3.1.-.-]" }, { "name":"R0135_07495 rhlB; (GenBank) ATP-dependent RNA helicase RhlB\tK03732 rhlB; ATP-dependent RNA helicase RhlB [EC:5.6.2.7]" }, { "name":"R0135_00315 DEAD\/DEAH box helicase\tK11927 rhlE; ATP-dependent RNA helicase RhlE [EC:5.6.2.7]" }, { "name":"R0135_06625 DEAD\/DEAH box helicase\tK11927 rhlE; ATP-dependent RNA helicase RhlE [EC:5.6.2.7]" }, { "name":"R0135_16490 DEAD\/DEAH box helicase\tK05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7]" }, { "name":"R0135_06680 recQ; (GenBank) DNA helicase RecQ\tK03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]" }, { "name":"R0135_05390 eno; (GenBank) phosphopyruvate hydratase\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]" }, { "name":"R0135_08665 pnp; (GenBank) polyribonucleotide nucleotidyltransferase\tK00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]" }, { "name":"R0135_09625 rho; (GenBank) transcription termination factor Rho\tK03628 rho; transcription termination factor Rho" }, { "name":"R0135_16630 dnaK; (GenBank) molecular chaperone DnaK\tK04043 dnaK; molecular chaperone DnaK" }, { "name":"R0135_16930 groL; (GenBank) chaperonin GroEL\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]" }, { "name":"R0135_14970 hfq; (GenBank) RNA chaperone Hfq\tK03666 hfq; host factor-I protein" }, { "name":"R0135_02020 ppk1; (GenBank) polyphosphate kinase 1\tK00937 ppk1; polyphosphate kinase [EC:2.7.4.1]" }, { "name":"R0135_00525 ppk2; (GenBank) polyphosphate kinase 2\tK22468 ppk2; polyphosphate kinase [EC:2.7.4.34]" }, { "name":"R0135_13270 ppk2; (GenBank) polyphosphate kinase 2\tK22468 ppk2; polyphosphate kinase [EC:2.7.4.34]" }, { "name":"R0135_08630 pcnB; (GenBank) polynucleotide adenylyltransferase PcnB\tK00970 pcnB; poly(A) polymerase [EC:2.7.7.19]" }, { "name":"R0135_11170 RNA pyrophosphohydrolase\tK08311 nudH; putative (di)nucleoside polyphosphate hydrolase [EC:3.6.1.-]" }, { "name":"R0135_00210 csrA; (GenBank) carbon storage regulator CsrA\tK03563 csrA; carbon storage regulator" }, { "name":"R0135_07110 rraA; (GenBank) ribonuclease E activity regulator RraA\tK02553 rraA; regulator of ribonuclease activity A" }, { "name":"R0135_07415 rapZ; (GenBank) RNase adapter RapZ\tK06958 rapZ; RNase adapter protein RapZ" }, { "name":"R0135_04670 hrpA; (GenBank) ATP-dependent RNA helicase HrpA\tK03578 hrpA; ATP-dependent RNA helicase HrpA [EC:5.6.2.6]" }, { "name":"R0135_08875 hrpB; (GenBank) ATP-dependent helicase HrpB\tK03579 hrpB; ATP-dependent RNA helicase HrpB [EC:5.6.2.6]" } ] }, { "name":"03041 Spliceosome" }, { "name":"03011 Ribosome [BR:cvb03011]", "children":[ { "name":"R0135_06785 rpsA; (GenBank) 30S ribosomal protein S1\tK02945 RP-S1; small subunit ribosomal protein S1" }, { "name":"R0135_00025 rpsB; (GenBank) 30S ribosomal protein S2\tK02967 RP-S2; small subunit ribosomal protein S2" }, { "name":"R0135_15765 rpsC; (GenBank) 30S ribosomal protein S3\tK02982 RP-S3; small subunit ribosomal protein S3" }, { "name":"R0135_15855 rpsD; (GenBank) 30S ribosomal protein S4\tK02986 RP-S4; small subunit ribosomal protein S4" }, { "name":"R0135_15820 rpsE; (GenBank) 30S ribosomal protein S5\tK02988 RP-S5; small subunit ribosomal protein S5" }, { "name":"R0135_15370 rpsF; (GenBank) 30S ribosomal protein S6\tK02990 RP-S6; small subunit ribosomal protein S6" }, { "name":"R0135_15700 rpsG; (GenBank) 30S ribosomal protein S7\tK02992 RP-S7; small subunit ribosomal protein S7" }, { "name":"R0135_15805 rpsH; (GenBank) 30S ribosomal protein S8\tK02994 RP-S8; small subunit ribosomal protein S8" }, { "name":"R0135_07315 rpsI; (GenBank) 30S ribosomal protein S9\tK02996 RP-S9; small subunit ribosomal protein S9" }, { "name":"R0135_15730 rpsJ; (GenBank) 30S ribosomal protein S10\tK02946 RP-S10; small subunit ribosomal protein S10" }, { "name":"R0135_15850 rpsK; (GenBank) 30S ribosomal protein S11\tK02948 RP-S11; small subunit ribosomal protein S11" }, { "name":"R0135_15695 rpsL; (GenBank) 30S ribosomal protein S12\tK02950 RP-S12; small subunit ribosomal protein S12" }, { "name":"R0135_15845 rpsM; (GenBank) 30S ribosomal protein S13\tK02952 RP-S13; small subunit ribosomal protein S13" }, { "name":"R0135_15800 rpsN; (GenBank) 30S ribosomal protein S14\tK02954 RP-S14; small subunit ribosomal protein S14" }, { "name":"R0135_08670 rpsO; (GenBank) 30S ribosomal protein S15\tK02956 RP-S15; small subunit ribosomal protein S15" }, { "name":"R0135_00740 rpsP; (GenBank) 30S ribosomal protein S16\tK02959 RP-S16; small subunit ribosomal protein S16" }, { "name":"R0135_15780 rpsQ; (GenBank) 30S ribosomal protein S17\tK02961 RP-S17; small subunit ribosomal protein S17" }, { "name":"R0135_15375 rpsR; (GenBank) 30S ribosomal protein S18\tK02963 RP-S18; small subunit ribosomal protein S18" }, { "name":"R0135_15755 rpsS; (GenBank) 30S ribosomal protein S19\tK02965 RP-S19; small subunit ribosomal protein S19" }, { "name":"R0135_09445 rpsT; (GenBank) 30S ribosomal protein S20\tK02968 RP-S20; small subunit ribosomal protein S20" }, { "name":"R0135_14340 rpsU; (GenBank) 30S ribosomal protein S21\tK02970 RP-S21; small subunit ribosomal protein S21" }, { "name":"R0135_15665 rplA; (GenBank) 50S ribosomal protein L1\tK02863 RP-L1; large subunit ribosomal protein L1" }, { "name":"R0135_15750 rplB; (GenBank) 50S ribosomal protein L2\tK02886 RP-L2; large subunit ribosomal protein L2" }, { "name":"R0135_15735 rplC; (GenBank) 50S ribosomal protein L3\tK02906 RP-L3; large subunit ribosomal protein L3" }, { "name":"R0135_15740 rplD; (GenBank) 50S ribosomal protein L4\tK02926 RP-L4; large subunit ribosomal protein L4" }, { "name":"R0135_15795 rplE; (GenBank) 50S ribosomal protein L5\tK02931 RP-L5; large subunit ribosomal protein L5" }, { "name":"R0135_15810 rplF; (GenBank) 50S ribosomal protein L6\tK02933 RP-L6; large subunit ribosomal protein L6" }, { "name":"R0135_15385 rplI; (GenBank) 50S ribosomal protein L9\tK02939 RP-L9; large subunit ribosomal protein L9" }, { "name":"R0135_15670 rplJ; (GenBank) 50S ribosomal protein L10\tK02864 RP-L10; large subunit ribosomal protein L10" }, { "name":"R0135_15660 rplK; (GenBank) 50S ribosomal protein L11\tK02867 RP-L11; large subunit ribosomal protein L11" }, { "name":"R0135_15675 rplL; (GenBank) 50S ribosomal protein L7\/L12\tK02935 RP-L7; large subunit ribosomal protein L7\/L12" }, { "name":"R0135_07320 rplM; (GenBank) 50S ribosomal protein L13\tK02871 RP-L13; large subunit ribosomal protein L13" }, { "name":"R0135_15785 rplN; (GenBank) 50S ribosomal protein L14\tK02874 RP-L14; large subunit ribosomal protein L14" }, { "name":"R0135_15830 rplO; (GenBank) 50S ribosomal protein L15\tK02876 RP-L15; large subunit ribosomal protein L15" }, { "name":"R0135_15770 rplP; (GenBank) 50S ribosomal protein L16\tK02878 RP-L16; large subunit ribosomal protein L16" }, { "name":"R0135_15865 rplQ; (GenBank) 50S ribosomal protein L17\tK02879 RP-L17; large subunit ribosomal protein L17" }, { "name":"R0135_15815 rplR; (GenBank) 50S ribosomal protein L18\tK02881 RP-L18; large subunit ribosomal protein L18" }, { "name":"R0135_00755 rplS; (GenBank) 50S ribosomal protein L19\tK02884 RP-L19; large subunit ribosomal protein L19" }, { "name":"R0135_06080 rplT; (GenBank) 50S ribosomal protein L20\tK02887 RP-L20; large subunit ribosomal protein L20" }, { "name":"R0135_15930 rplU; (GenBank) 50S ribosomal protein L21\tK02888 RP-L21; large subunit ribosomal protein L21" }, { "name":"R0135_15760 rplV; (GenBank) 50S ribosomal protein L22\tK02890 RP-L22; large subunit ribosomal protein L22" }, { "name":"R0135_15745 rplW; (GenBank) 50S ribosomal protein L23\tK02892 RP-L23; large subunit ribosomal protein L23" }, { "name":"R0135_15790 rplX; (GenBank) 50S ribosomal protein L24\tK02895 RP-L24; large subunit ribosomal protein L24" }, { "name":"R0135_15935 rpmA; (GenBank) 50S ribosomal protein L27\tK02899 RP-L27; large subunit ribosomal protein L27" }, { "name":"R0135_11460 rpmB; (GenBank) 50S ribosomal protein L28\tK02902 RP-L28; large subunit ribosomal protein L28" }, { "name":"R0135_15775 rpmC; (GenBank) 50S ribosomal protein L29\tK02904 RP-L29; large subunit ribosomal protein L29" }, { "name":"R0135_15825 rpmD; (GenBank) 50S ribosomal protein L30\tK02907 RP-L30; large subunit ribosomal protein L30" }, { "name":"R0135_12665 rpmE; (GenBank) 50S ribosomal protein L31\tK02909 RP-L31; large subunit ribosomal protein L31" }, { "name":"R0135_03120 rpmF; (GenBank) 50S ribosomal protein L32\tK02911 RP-L32; large subunit ribosomal protein L32" }, { "name":"R0135_11455 rpmG; (GenBank) 50S ribosomal protein L33\tK02913 RP-L33; large subunit ribosomal protein L33" }, { "name":"R0135_11740 rpmH; (GenBank) 50S ribosomal protein L34\tK02914 RP-L34; large subunit ribosomal protein L34" }, { "name":"R0135_06085 rpmI; (GenBank) 50S ribosomal protein L35\tK02916 RP-L35; large subunit ribosomal protein L35" }, { "name":"R0135_15840 rpmJ; (GenBank) 50S ribosomal protein L36\tK02919 RP-L36; large subunit ribosomal protein L36" }, { "name":"R0135_07560 50S ribosomal protein L25\/general stress protein Ctc\tK02897 RP-L25; large subunit ribosomal protein L25" }, { "name":"R0135_14690 16S ribosomal RNA\tK01977 16SrRNA; 16S ribosomal RNA" }, { "name":"R0135_17090 16S ribosomal RNA\tK01977 16SrRNA; 16S ribosomal RNA" }, { "name":"R0135_14710 rrf; (GenBank) 5S ribosomal RNA\tK01985 5SrRNA; 5S ribosomal RNA" }, { "name":"R0135_17110 rrf; (GenBank) 5S ribosomal RNA\tK01985 5SrRNA; 5S ribosomal RNA" } ] }, { "name":"03009 Ribosome biogenesis [BR:cvb03009]", "children":[ { "name":"R0135_01815 rnc; (GenBank) ribonuclease III\tK03685 rnc; ribonuclease III [EC:3.1.26.3]" }, { "name":"R0135_16485 PA4780 family RIO1-like protein kinase\tK07178 RIOK1; RIO kinase 1 [EC:2.7.11.1]" }, { "name":"R0135_14935 orn; (GenBank) oligoribonuclease\tK13288 orn; oligoribonuclease [EC:3.1.-.-]" }, { "name":"R0135_01820 era; (GenBank) GTPase Era\tK03595 era; GTPase" }, { "name":"R0135_15940 cgtA; (GenBank) Obg family GTPase CgtA\tK03979 obgE; GTPase [EC:3.6.5.-]" }, { "name":"R0135_08610 dksA; (GenBank) RNA polymerase-binding protein DksA\tK06204 dksA; RNA polymerase-binding transcription factor" }, { "name":"R0135_08690 nusA; (GenBank) transcription termination factor NusA\tK02600 nusA; transcription termination\/antitermination protein NusA" }, { "name":"R0135_15460 nusB; (GenBank) transcription antitermination factor NusB\tK03625 nusB; transcription antitermination protein NusB" }, { "name":"R0135_15655 nusG; (GenBank) transcription termination\/antitermination protein NusG\tK02601 nusG; transcription termination\/antitermination protein NusG" }, { "name":"R0135_06595 pseudouridine synthase\tK06183 rsuA; 16S rRNA pseudouridine516 synthase [EC:5.4.99.19]" }, { "name":"R0135_14380 rsmA; (GenBank) 16S rRNA (adenine(1518)-N(6)\/adenine(1519)-N(6))-dimethyltransferase RsmA\tK02528 ksgA; 16S rRNA (adenine1518-N6\/adenine1519-N6)-dimethyltransferase [EC:2.1.1.182]" }, { "name":"R0135_11895 rsmB; (GenBank) 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB\tK03500 rsmB; 16S rRNA (cytosine967-C5)-methyltransferase [EC:2.1.1.176]" }, { "name":"R0135_11435 rsmD; (GenBank) 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD\tK08316 rsmD; 16S rRNA (guanine966-N2)-methyltransferase [EC:2.1.1.171]" }, { "name":"R0135_11330 16S rRNA (uracil(1498)-N(3))-methyltransferase\tK09761 rsmE; 16S rRNA (uracil1498-N3)-methyltransferase [EC:2.1.1.193]" }, { "name":"R0135_11710 rsmG; (GenBank) 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG\tK03501 gidB; 16S rRNA (guanine527-N7)-methyltransferase [EC:2.1.1.170]" }, { "name":"R0135_07255 rsmH; (GenBank) 16S rRNA (cytosine(1402)-N(4))-methyltransferase RsmH\tK03438 mraW; 16S rRNA (cytosine1402-N4)-methyltransferase [EC:2.1.1.199]" }, { "name":"R0135_07270 rsmI; (GenBank) 16S rRNA (cytidine(1402)-2'-O)-methyltransferase\tK07056 rsmI; 16S rRNA (cytidine1402-2'-O)-methyltransferase [EC:2.1.1.198]" }, { "name":"R0135_17550 class I SAM-dependent methyltransferase\tK15984 rsmJ; 16S rRNA (guanine1516-N2)-methyltransferase [EC:2.1.1.242]" }, { "name":"R0135_06660 methyltransferase domain-containing protein\tK00563 rlmA1; 23S rRNA (guanine745-N1)-methyltransferase [EC:2.1.1.187]" }, { "name":"R0135_03555 RNA methyltransferase\tK03218 rlmB; 23S rRNA (guanosine2251-2'-O)-methyltransferase [EC:2.1.1.185]" }, { "name":"R0135_15365 rlmB; (GenBank) 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB\tK03218 rlmB; 23S rRNA (guanosine2251-2'-O)-methyltransferase [EC:2.1.1.185]" }, { "name":"R0135_08735 rlmE; (GenBank) 23S rRNA (uridine(2552)-2'-O)-methyltransferase RlmE\tK02427 rlmE; 23S rRNA (uridine2552-2'-O)-methyltransferase [EC:2.1.1.166]" }, { "name":"R0135_10515 methyltransferase\tK11391 rlmG; 23S rRNA (guanine1835-N2)-methyltransferase [EC:2.1.1.174]" }, { "name":"R0135_09325 rlmH; (GenBank) 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH\tK00783 rlmH; 23S rRNA (pseudouridine1915-N3)-methyltransferase [EC:2.1.1.177]" }, { "name":"R0135_03920 rlmKL; (GenBank) bifunctional 23S rRNA (guanine(2069)-N(7))-methyltransferase RlmK\/23S rRNA (guanine(2445)-N(2))-methyltransferase RlmL\tK12297 rlmKL; 23S rRNA (guanine2069-N7)-methyltransferase \/ 23S rRNA (guanine2445-N2)-methyltransferase [EC:2.1.1.264 2.1.1.173]" }, { "name":"R0135_00970 rlmN; (GenBank) 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN\tK06941 rlmN; 23S rRNA (adenine2503-C2)-methyltransferase [EC:2.1.1.192]" }, { "name":"R0135_16390 class I SAM-dependent RNA methyltransferase\tK03215 rumA; 23S rRNA (uracil1939-C5)-methyltransferase [EC:2.1.1.190]" }, { "name":"R0135_06885 RluA family pseudouridine synthase\tK06177 rluA; tRNA pseudouridine32 synthase \/ 23S rRNA pseudouridine746 synthase [EC:5.4.99.28 5.4.99.29]" }, { "name":"R0135_06840 pseudouridine synthase\tK06178 rluB; 23S rRNA pseudouridine2605 synthase [EC:5.4.99.22]" }, { "name":"R0135_03135 RluA family pseudouridine synthase\tK06179 rluC; 23S rRNA pseudouridine955\/2504\/2580 synthase [EC:5.4.99.24]" }, { "name":"R0135_17045 rluD; (GenBank) 23S rRNA pseudouridine(1911\/1915\/1917) synthase RluD\tK06180 rluD; 23S rRNA pseudouridine1911\/1915\/1917 synthase [EC:5.4.99.23]" }, { "name":"R0135_02620 pseudouridine synthase\tK06181 rluE; 23S rRNA pseudouridine2457 synthase [EC:5.4.99.20]" }, { "name":"R0135_17355 rimI; (GenBank) ribosomal protein S18-alanine N-acetyltransferase\tK03789 rimI; [ribosomal protein S18]-alanine N-acetyltransferase \/ [ribosomal protein L31]-L-lysine N-acetyltransferase [EC:2.3.1.266 2.3.1.338]" }, { "name":"R0135_11650 rimK; (GenBank) 30S ribosomal protein S6--L-glutamate ligase\tK05844 rimK; ribosomal protein S6--L-glutamate ligase [EC:6.3.2.-]" }, { "name":"R0135_04350 GNAT family N-acetyltransferase\tK03817 rimL; ribosomal-protein-serine acetyltransferase [EC:2.3.1.-]" }, { "name":"R0135_00745 rimM; (GenBank) ribosome maturation factor RimM\tK02860 rimM; 16S rRNA processing protein RimM" }, { "name":"R0135_06905 rimO; (GenBank) 30S ribosomal protein S12 methylthiotransferase RimO\tK14441 rimO; ribosomal protein S12 methylthiotransferase [EC:2.8.4.4]" }, { "name":"R0135_05950 OsmC domain\/YcaO domain-containing protein\tK09136 ycaO; ribosomal protein S12 methylthiotransferase accessory factor" }, { "name":"R0135_14575 prmA; (GenBank) 50S ribosomal protein L11 methyltransferase\tK02687 prmA; ribosomal protein L11 methyltransferase [EC:2.1.1.-]" }, { "name":"R0135_02300 prmB; (GenBank) 50S ribosomal protein L3 N(5)-glutamine methyltransferase\tK07320 prmB; ribosomal protein L3 glutamine methyltransferase [EC:2.1.1.298]" }, { "name":"R0135_02600 cupin domain-containing protein\tK18850 ycfD; 50S ribosomal protein L16 3-hydroxylase [EC:1.14.11.47]" }, { "name":"R0135_03140 rne; (GenBank) ribonuclease E\tK08300 rne; ribonuclease E [EC:3.1.26.12]" }, { "name":"R0135_07440 rng; (GenBank) ribonuclease G\tK08301 rng; ribonuclease G [EC:3.1.26.-]" }, { "name":"R0135_11350 ruvX; (GenBank) Holliday junction resolvase RuvX\tK07447 ruvX; putative pre-16S rRNA nuclease [EC:3.1.-.-]" }, { "name":"R0135_04810 dbpA; (GenBank) ATP-dependent RNA helicase DbpA\tK05591 dbpA; ATP-dependent RNA helicase DbpA [EC:5.6.2.6]" }, { "name":"R0135_16490 DEAD\/DEAH box helicase\tK05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7]" }, { "name":"R0135_14930 rsgA; (GenBank) small ribosomal subunit biogenesis GTPase RsgA\tK06949 rsgA; ribosome biogenesis GTPase \/ thiamine phosphate phosphatase [EC:3.6.1.- 3.1.3.100]" }, { "name":"R0135_01000 der; (GenBank) ribosome biogenesis GTPase Der\tK03977 engA; GTPase" }, { "name":"R0135_14975 hflX; (GenBank) ribosome rescue GTPase HflX\tK03665 hflX; GTPase" }, { "name":"R0135_11920 L-threonylcarbamoyladenylate synthase\tK07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]" }, { "name":"R0135_11525 RelA\/SpoT family protein\tK01139 spoT; GTP diphosphokinase \/ guanosine-3',5'-bis(diphosphate) 3'-diphosphatase [EC:2.7.6.5 3.1.7.2]" }, { "name":"R0135_08680 rbfA; (GenBank) 30S ribosome-binding factor RbfA\tK02834 rbfA; ribosome-binding factor A" }, { "name":"R0135_08695 rimP; (GenBank) ribosome maturation factor RimP\tK09748 rimP; ribosome maturation factor RimP" }, { "name":"R0135_13740 RNA-binding S4 domain-containing protein\tK14761 rlbA; ribosome-associated protein" }, { "name":"R0135_09330 rsfS; (GenBank) ribosome silencing factor\tK09710 ybeB; ribosome-associated protein" }, { "name":"R0135_08385 ybeY; (GenBank) rRNA maturation RNase YbeY\tK07042 ybeY; probable rRNA maturation factor" }, { "name":"R0135_08740 YhbY family RNA-binding protein\tK07574 yhbY; RNA-binding protein" }, { "name":"R0135_07430 yjgA; (GenBank) ribosome biogenesis factor YjgA\tK09889 yjgA; ribosome-associated protein" }, { "name":"R0135_04190 rmf; (GenBank) ribosome modulation factor\tK03812 rmf; ribosome modulation factor" }, { "name":"R0135_07405 raiA; (GenBank) ribosome-associated translation inhibitor RaiA\tK05808 hpf; ribosome hibernation promoting factor" }, { "name":"R0135_07570 ychF; (GenBank) redox-regulated ATPase YchF\tK06942 ychF; ribosome-binding ATPase" }, { "name":"R0135_03125 YceD family protein\tK07040 yceD; DUF177 domain-containing protein" } ] }, { "name":"03016 Transfer RNA biogenesis [BR:cvb03016]", "children":[ { "name":"R0135_04875 MBL fold metallo-hydrolase\tK00784 rnz; ribonuclease Z [EC:3.1.26.11]" }, { "name":"R0135_14360 multifunctional CCA addition\/repair protein\tK00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]" }, { "name":"R0135_04595 gltX; (GenBank) glutamate--tRNA ligase\tK01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]" }, { "name":"R0135_09245 proline--tRNA ligase\tK01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]" }, { "name":"R0135_16980 ileS; (GenBank) isoleucine--tRNA ligase\tK01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]" }, { "name":"R0135_08400 leuS; (GenBank) leucine--tRNA ligase\tK01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]" }, { "name":"R0135_17395 metG; (GenBank) methionine--tRNA ligase\tK01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]" }, { "name":"R0135_03645 glutamine--tRNA ligase\/YqeY domain fusion protein\tK01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18]" }, { "name":"R0135_12655 argS; (GenBank) arginine--tRNA ligase\tK01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]" }, { "name":"R0135_00795 lysS; (GenBank) lysine--tRNA ligase\tK04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]" }, { "name":"R0135_09230 aspS; (GenBank) aspartate--tRNA ligase\tK01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]" }, { "name":"R0135_00200 alaS; (GenBank) alanine--tRNA ligase\tK01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]" }, { "name":"R0135_14910 asnS; (GenBank) asparagine--tRNA ligase\tK01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]" }, { "name":"R0135_06095 thrS; (GenBank) threonine--tRNA ligase\tK01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]" }, { "name":"R0135_02680 serS; (GenBank) serine--tRNA ligase\tK01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]" }, { "name":"R0135_03640 cysS; (GenBank) cysteine--tRNA ligase\tK01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]" }, { "name":"R0135_01615 valine--tRNA ligase\tK01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]" }, { "name":"R0135_00985 hisS; (GenBank) histidine--tRNA ligase\tK01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]" }, { "name":"R0135_06075 pheS; (GenBank) phenylalanine--tRNA ligase subunit alpha\tK01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]" }, { "name":"R0135_06070 pheT; (GenBank) phenylalanine--tRNA ligase subunit beta\tK01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]" }, { "name":"R0135_14685 tyrS; (GenBank) tyrosine--tRNA ligase\tK01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]" }, { "name":"R0135_01880 trpS; (GenBank) tryptophan--tRNA ligase\tK01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]" }, { "name":"R0135_12445 dtd; (GenBank) D-aminoacyl-tRNA deacylase\tK07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]" }, { "name":"R0135_00195 histidine triad nucleotide-binding protein\tK02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]" }, { "name":"R0135_08375 miaB; (GenBank) tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB\tK06168 CDK5RAP1; tRNA-2-methylthio-N6-dimethylallyladenosine synthase [EC:2.8.4.3]" }, { "name":"R0135_11405 trmB; (GenBank) tRNA (guanosine(46)-N7)-methyltransferase TrmB\tK03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33]" }, { "name":"R0135_12750 SAM-dependent methyltransferase\tK03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33]" }, { "name":"R0135_03875 truA; (GenBank) tRNA pseudouridine(38-40) synthase TruA\tK06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]" }, { "name":"R0135_08675 truB; (GenBank) tRNA pseudouridine(55) synthase TruB\tK03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]" }, { "name":"R0135_13980 tRNA pseudouridine(13) synthase TruD\tK06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]" }, { "name":"R0135_00960 IscS subfamily cysteine desulfurase\tK04487 iscS; cysteine desulfurase [EC:2.8.1.7]" }, { "name":"R0135_11920 L-threonylcarbamoyladenylate synthase\tK07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]" }, { "name":"R0135_14965 miaA; (GenBank) tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA\tK00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]" }, { "name":"R0135_11720 mnmE; (GenBank) tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE\tK03650 mnmE; tRNA modification GTPase [EC:3.6.-.-]" }, { "name":"R0135_11715 mnmG; (GenBank) tRNA uridine-5-carboxymethylaminomethyl(34) synthesis enzyme MnmG\tK03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme" }, { "name":"R0135_15545 cysQ; (GenBank) 3'(2'),5'-bisphosphate nucleotidase CysQ\tK01082 cysQ; 3'(2'), 5'-bisphosphate nucleotidase [EC:3.1.3.7]" }, { "name":"R0135_11735 rnpA; (GenBank) ribonuclease P protein component\tK03536 rnpA; ribonuclease P protein component [EC:3.1.26.5]" }, { "name":"R0135_07265 rnpB; (GenBank) RNase P RNA component class A\tK01978 rnpB; RNase P catalytic RNA component" }, { "name":"R0135_08570 rnt; (GenBank) ribonuclease T\tK03683 rnt; ribonuclease T [EC:3.1.13.-]" }, { "name":"R0135_11505 rph; (GenBank) ribonuclease PH\tK00989 rph; ribonuclease PH [EC:2.7.7.56]" }, { "name":"R0135_14915 VacB\/RNase II family 3'-5' exoribonuclease\tK01147 rnb; exoribonuclease II [EC:3.1.13.1]" }, { "name":"R0135_03580 rnd; (GenBank) ribonuclease D\tK03684 rnd; ribonuclease D [EC:3.1.13.5]" }, { "name":"R0135_09050 thpR; (GenBank) RNA 2',3'-cyclic phosphodiesterase\tK01975 thpR; RNA 2',3'-cyclic 3'-phosphodiesterase [EC:3.1.4.58]" }, { "name":"R0135_15425 ettA; (GenBank) energy-dependent translational throttle protein EttA\tK06020 ettA; energy-dependent translational throttle protein EttA" }, { "name":"R0135_11835 glyQ; (GenBank) glycine--tRNA ligase subunit alpha\tK01878 glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14]" }, { "name":"R0135_11830 glyS; (GenBank) glycine--tRNA ligase subunit beta\tK01879 glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14]" }, { "name":"R0135_08615 gluQRS; (GenBank) tRNA glutamyl-Q(34) synthetase GluQRS\tK01894 gluQ; glutamyl-Q tRNA(Asp) synthetase [EC:6.1.1.-]" }, { "name":"R0135_00925 tadA; (GenBank) tRNA adenosine(34) deaminase TadA\tK11991 tadA; tRNA(adenine34) deaminase [EC:3.5.4.33]" }, { "name":"R0135_04625 dusA; (GenBank) tRNA dihydrouridine(20\/20a) synthase DusA\tK05539 dusA; tRNA-dihydrouridine synthase A [EC:1.-.-.-]" }, { "name":"R0135_14570 dusB; (GenBank) tRNA dihydrouridine synthase DusB\tK05540 dusB; tRNA-dihydrouridine synthase B [EC:1.-.-.-]" }, { "name":"R0135_05430 tRNA-dihydrouridine synthase\tK05541 dusC; tRNA-dihydrouridine synthase C [EC:1.-.-.-]" }, { "name":"R0135_08355 cmoA; (GenBank) carboxy-S-adenosyl-L-methionine synthase CmoA\tK15256 cmoA; tRNA (cmo5U34)-methyltransferase [EC:2.1.1.-]" }, { "name":"R0135_08360 cmoB; (GenBank) tRNA 5-methoxyuridine(34)\/uridine 5-oxyacetic acid(34) synthase CmoB\tK15257 cmoB; tRNA (mo5U34)-methyltransferase [EC:2.1.1.-]" }, { "name":"R0135_03225 trmA; (GenBank) tRNA (uridine(54)-C5)-methyltransferase TrmA\tK00557 trmA; tRNA (uracil-5-)-methyltransferase [EC:2.1.1.35]" }, { "name":"R0135_00750 trmD; (GenBank) tRNA (guanosine(37)-N1)-methyltransferase TrmD\tK00554 trmD; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228]" }, { "name":"R0135_00955 RNA methyltransferase\tK15396 trmJ; tRNA (cytidine32\/uridine32-2'-O)-methyltransferase [EC:2.1.1.200]" }, { "name":"R0135_12415 trmL; (GenBank) tRNA (uridine(34)\/cytosine(34)\/5-carboxymethylaminomethyluridine(34)-2'-O)-methyltransferase TrmL\tK03216 trmL; tRNA (cytidine\/uridine-2'-O-)-methyltransferase [EC:2.1.1.207]" }, { "name":"R0135_13885 truC; (GenBank) tRNA pseudouridine(65) synthase TruC\tK06175 truC; tRNA pseudouridine65 synthase [EC:5.4.99.26]" }, { "name":"R0135_06885 RluA family pseudouridine synthase\tK06177 rluA; tRNA pseudouridine32 synthase \/ 23S rRNA pseudouridine746 synthase [EC:5.4.99.28 5.4.99.29]" }, { "name":"R0135_02615 mnmA; (GenBank) tRNA 2-thiouridine(34) synthase MnmA\tK00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13]" }, { "name":"R0135_02120 ttcA; (GenBank) tRNA 2-thiocytidine(32) synthetase TtcA\tK14058 ttcA; tRNA 2-thiocytidine biosynthesis protein TtcA" }, { "name":"R0135_02330 tusA; (GenBank) sulfurtransferase TusA\tK04085 tusA; tRNA 2-thiouridine synthesizing protein A [EC:2.8.1.-]" }, { "name":"R0135_16735 sulfurtransferase TusA family protein\tK04085 tusA; tRNA 2-thiouridine synthesizing protein A [EC:2.8.1.-]" }, { "name":"R0135_03215 DsrH\/TusB family sulfur metabolism protein\tK07237 tusB; tRNA 2-thiouridine synthesizing protein B" }, { "name":"R0135_03210 DsrE family protein\tK07236 tusC; tRNA 2-thiouridine synthesizing protein C" }, { "name":"R0135_03205 tusD; (GenBank) sulfurtransferase complex subunit TusD\tK07235 tusD; tRNA 2-thiouridine synthesizing protein D [EC:2.8.1.-]" }, { "name":"R0135_03220 TusE\/DsrC\/DsvC family sulfur relay protein\tK11179 tusE; tRNA 2-thiouridine synthesizing protein E [EC:2.8.1.-]" }, { "name":"R0135_09995 iron-sulfur cluster assembly accessory protein\tK13628 iscA; iron-sulfur cluster assembly protein" }, { "name":"R0135_01755 folate-binding protein\tK06980 ygfZ; tRNA-modifying protein YgfZ" }, { "name":"R0135_03660 miaE; (GenBank) tRNA isopentenyl-2-thiomethyl-A-37 hydroxylase MiaE\tK06169 miaE; tRNA 2-(methylsulfanyl)-N6-isopentenyladenosine37 hydroxylase [EC:1.14.99.69]" }, { "name":"R0135_12825 tRNA-(ms[2]io[6]A)-hydroxylase\tK06169 miaE; tRNA 2-(methylsulfanyl)-N6-isopentenyladenosine37 hydroxylase [EC:1.14.99.69]" }, { "name":"R0135_04690 mnmC; (GenBank) bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD\/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC\tK15461 mnmC; tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein [EC:2.1.1.61 1.5.-.-]" }, { "name":"R0135_00705 queA; (GenBank) tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA\tK07568 queA; S-adenosylmethionine:tRNA ribosyltransferase-isomerase [EC:2.4.99.17]" }, { "name":"R0135_09165 queC; (GenBank) 7-cyano-7-deazaguanine synthase QueC\tK06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20]" }, { "name":"R0135_04385 queD; (GenBank) 6-carboxytetrahydropterin synthase QueD\tK01737 queD; 6-pyruvoyltetrahydropterin\/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50]" }, { "name":"R0135_17465 6-carboxytetrahydropterin synthase\tK01737 queD; 6-pyruvoyltetrahydropterin\/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50]" }, { "name":"R0135_09170 queE; (GenBank) 7-carboxy-7-deazaguanine synthase QueE\tK10026 queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3]" }, { "name":"R0135_02370 queF; (GenBank) NADPH-dependent 7-cyano-7-deazaguanine reductase QueF\tK06879 queF; 7-cyano-7-deazaguanine reductase [EC:1.7.1.13]" }, { "name":"R0135_14940 queG; (GenBank) tRNA epoxyqueuosine(34) reductase QueG\tK18979 queG; epoxyqueuosine reductase [EC:1.17.99.6]" }, { "name":"R0135_12250 mnmH; (GenBank) tRNA 2-selenouridine(34) synthase MnmH\tK06917 selU; tRNA 2-selenouridine synthase [EC:2.9.1.3]" }, { "name":"R0135_00710 tgt; (GenBank) tRNA guanosine(34) transglycosylase Tgt\tK00773 tgt; queuine tRNA-ribosyltransferase [EC:2.4.2.29]" }, { "name":"R0135_05405 tilS; (GenBank) tRNA lysidine(34) synthetase TilS\tK04075 tilS; tRNA(Ile)-lysidine synthase [EC:6.3.4.19]" }, { "name":"R0135_01860 tsaB; (GenBank) tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex dimerization subunit type 1 TsaB\tK14742 tsaB; tRNA threonylcarbamoyladenosine biosynthesis protein TsaB" }, { "name":"R0135_14345 tsaD; (GenBank) tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD\tK25706 tsaD; tRNA N6-adenosine threonylcarbamoyltransferase [EC:2.3.1.234]" }, { "name":"R0135_14950 tsaE; (GenBank) tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE\tK06925 tsaE; tRNA threonylcarbamoyladenosine biosynthesis protein TsaE" }, { "name":"R0135_15360 rnr; (GenBank) ribonuclease R\tK12573 rnr; ribonuclease R [EC:3.1.13.1]" }, { "name":"R0135_08665 pnp; (GenBank) polyribonucleotide nucleotidyltransferase\tK00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]" } ] }, { "name":"03012 Translation factors [BR:cvb03012]", "children":[ { "name":"R0135_04035 stress response translation initiation inhibitor YciH\tK03113 EIF1; translation initiation factor 1" }, { "name":"R0135_08685 infB; (GenBank) translation initiation factor IF-2\tK02519 infB; translation initiation factor IF-2" }, { "name":"R0135_06090 infC; (GenBank) translation initiation factor IF-3\tK02520 infC; translation initiation factor IF-3" }, { "name":"R0135_09605 ATP-binding cassette domain-containing protein\tK06158 ABCF3; ATP-binding cassette, subfamily F, member 3" }, { "name":"R0135_00030 tsf; (GenBank) translation elongation factor Ts\tK02357 tsf; elongation factor Ts" }, { "name":"R0135_15640 tuf; (GenBank) elongation factor Tu\tK02358 tuf; elongation factor Tu" }, { "name":"R0135_15710 tuf; (GenBank) elongation factor Tu\tK02358 tuf; elongation factor Tu" }, { "name":"R0135_09815 fusA; (GenBank) elongation factor G\tK02355 fusA; elongation factor G" }, { "name":"R0135_15705 fusA; (GenBank) elongation factor G\tK02355 fusA; elongation factor G" }, { "name":"R0135_07515 prfA; (GenBank) peptide chain release factor 1\tK02835 prfA; peptide chain release factor 1" }, { "name":"R0135_00040 frr; (GenBank) ribosome recycling factor\tK02838 frr; ribosome recycling factor" }, { "name":"R0135_07510 prmC; (GenBank) peptide chain release factor N(5)-glutamine methyltransferase\tK02493 hemK; release factor glutamine methyltransferase [EC:2.1.1.297]" }, { "name":"R0135_07565 pth; (GenBank) aminoacyl-tRNA hydrolase\tK01056 PTH1; peptidyl-tRNA hydrolase, PTH1 family [EC:3.1.1.29]" }, { "name":"R0135_02640 infA; (GenBank) translation initiation factor IF-1\tK02518 infA; translation initiation factor IF-1" }, { "name":"R0135_12495 efp; (GenBank) elongation factor P\tK02356 efp; elongation factor P" }, { "name":"R0135_12500 epmA; (GenBank) EF-P lysine aminoacylase EpmA\tK04568 epmA; elongation factor P--(R)-beta-lysine ligase [EC:6.3.1.-]" }, { "name":"R0135_12875 epmB; (GenBank) EF-P beta-lysylation protein EpmB\tK19810 epmB; L-lysine 2,3-aminomutase [EC:5.4.3.-]" }, { "name":"R0135_02335 elongation factor P hydroxylase\tK09906 epmC; elongation factor P hydroxylase [EC:1.14.-.-]" }, { "name":"R0135_00790 prfB; (GenBank) peptide chain release factor 2\tK02836 prfB; peptide chain release factor 2" }, { "name":"R0135_09285 peptide chain release factor 3\tK02837 prfC; peptide chain release factor 3" }, { "name":"R0135_02470 arfB; (GenBank) alternative ribosome rescue aminoacyl-tRNA hydrolase ArfB\tK15034 yaeJ; ribosome-associated protein" } ] }, { "name":"03110 Chaperones and folding catalysts [BR:cvb03110]", "children":[ { "name":"R0135_02635 clpA; (GenBank) ATP-dependent Clp protease ATP-binding subunit ClpA\tK03694 clpA; ATP-dependent Clp protease ATP-binding subunit ClpA" }, { "name":"R0135_17055 clpB; (GenBank) ATP-dependent chaperone ClpB\tK03695 clpB; ATP-dependent Clp protease ATP-binding subunit ClpB" }, { "name":"R0135_03050 clpX; (GenBank) ATP-dependent Clp protease ATP-binding subunit ClpX\tK03544 clpX; ATP-dependent Clp protease ATP-binding subunit ClpX" }, { "name":"R0135_12640 hslU; (GenBank) ATP-dependent protease ATPase subunit HslU\tK03667 hslU; ATP-dependent HslUV protease ATP-binding subunit HslU" }, { "name":"R0135_02285 htpG; (GenBank) molecular chaperone HtpG\tK04079 HSP90A; molecular chaperone HtpG" }, { "name":"R0135_16630 dnaK; (GenBank) molecular chaperone DnaK\tK04043 dnaK; molecular chaperone DnaK" }, { "name":"R0135_16930 groL; (GenBank) chaperonin GroEL\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]" }, { "name":"R0135_16635 dnaJ; (GenBank) molecular chaperone DnaJ\tK03686 dnaJ; molecular chaperone DnaJ" }, { "name":"R0135_00880 DnaJ C-terminal domain-containing protein\tK05516 cbpA; curved DNA-binding protein" }, { "name":"R0135_11845 djlA; (GenBank) co-chaperone DjlA\tK05801 djlA; DnaJ like chaperone protein" }, { "name":"R0135_09495 hslO; (GenBank) Hsp33 family molecular chaperone HslO\tK04083 hslO; molecular chaperone Hsp33" }, { "name":"R0135_16625 grpE; (GenBank) nucleotide exchange factor GrpE\tK03687 GRPE; molecular chaperone GrpE" }, { "name":"R0135_15195 Hsp20\/alpha crystallin family protein\tK13993 HSP20; HSP20 family protein" }, { "name":"R0135_09970 Hsp20 family protein\tK04080 ibpA; molecular chaperone IbpA" }, { "name":"R0135_15535 S4 domain-containing protein\tK04762 hslR; ribosome-associated heat shock protein Hsp15" }, { "name":"R0135_16925 co-chaperone GroES\tK04078 groES; chaperonin GroES" }, { "name":"R0135_01795 Do family serine endopeptidase\tK04771 degP; serine protease Do [EC:3.4.21.107]" }, { "name":"R0135_08150 trypsin-like peptidase domain-containing protein\tK04771 degP; serine protease Do [EC:3.4.21.107]" }, { "name":"R0135_15210 Do family serine endopeptidase\tK04771 degP; serine protease Do [EC:3.4.21.107]" }, { "name":"R0135_08730 ftsH; (GenBank) ATP-dependent zinc metalloprotease FtsH\tK03798 ftsH; cell division protease FtsH [EC:3.4.24.-]" }, { "name":"R0135_15185 ftsH; (GenBank) ATP-dependent zinc metalloprotease FtsH\tK03798 ftsH; cell division protease FtsH [EC:3.4.24.-]" }, { "name":"R0135_11690 atpB; (GenBank) F0F1 ATP synthase subunit A\tK02108 ATPF0A; F-type H+-transporting ATPase subunit a" }, { "name":"R0135_15270 F0F1 ATP synthase subunit A\tK02108 ATPF0A; F-type H+-transporting ATPase subunit a" }, { "name":"R0135_12410 secB; (GenBank) protein-export chaperone SecB\tK03071 secB; preprotein translocase subunit SecB" }, { "name":"R0135_14600 copper chaperone PCu(A)C\tK09796 pccA; periplasmic copper chaperone A" }, { "name":"R0135_15315 hydrogenase maturation nickel metallochaperone HypA\tK04651 hypA; hydrogenase nickel incorporation protein HypA\/HybF" }, { "name":"R0135_10805 S8 family serine peptidase\tK14645 K14645; serine protease [EC:3.4.21.-]" }, { "name":"R0135_06875 peptidylprolyl isomerase\tK03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8]" }, { "name":"R0135_03650 peptidylprolyl isomerase\tK03768 PPIB; peptidyl-prolyl cis-trans isomerase B (cyclophilin B) [EC:5.2.1.8]" }, { "name":"R0135_03035 SurA N-terminal domain-containing protein\tK03770 ppiD; peptidyl-prolyl cis-trans isomerase D [EC:5.2.1.8]" }, { "name":"R0135_09590 FKBP-type peptidyl-prolyl cis-trans isomerase\tK03773 fklB; FKBP-type peptidyl-prolyl cis-trans isomerase FklB [EC:5.2.1.8]" }, { "name":"R0135_16990 peptidylprolyl isomerase\tK03774 slpA; FKBP-type peptidyl-prolyl cis-trans isomerase SlpA [EC:5.2.1.8]" }, { "name":"R0135_04915 peptidylprolyl isomerase\tK03775 slyD; FKBP-type peptidyl-prolyl cis-trans isomerase SlyD [EC:5.2.1.8]" }, { "name":"R0135_16860 peptidylprolyl isomerase\tK03769 ppiC; peptidyl-prolyl cis-trans isomerase C [EC:5.2.1.8]" }, { "name":"R0135_14495 peptidylprolyl isomerase\tK03771 surA; peptidyl-prolyl cis-trans isomerase SurA [EC:5.2.1.8]" }, { "name":"R0135_09620 trxA; (GenBank) thioredoxin TrxA\tK03671 TXN; thioredoxin" }, { "name":"R0135_10540 trxC; (GenBank) thioredoxin TrxC\tK03672 trxC; thioredoxin 2 [EC:1.8.1.8]" }, { "name":"R0135_16645 trxA; (GenBank) thioredoxin\tK05838 ybbN; putative thioredoxin" }, { "name":"R0135_12405 grxC; (GenBank) glutaredoxin 3\tK03676 grxC; glutaredoxin 3" }, { "name":"R0135_09355 grxD; (GenBank) Grx4 family monothiol glutaredoxin\tK07390 grxD; monothiol glutaredoxin" }, { "name":"R0135_12020 thiol:disulfide interchange protein DsbA\/DsbL\tK03673 dsbA; protein dithiol oxidoreductase (disulfide-forming) [EC:1.8.4.15]" }, { "name":"R0135_09585 disulfide bond formation protein B\tK03611 dsbB; protein dithiol:quinone oxidoreductase [EC:1.8.5.9]" }, { "name":"R0135_00765 DsbC family protein\tK03981 dsbC; thiol:disulfide interchange protein DsbC [EC:5.3.4.1]" }, { "name":"R0135_02155 DsbE family thiol:disulfide interchange protein\tK02199 ccmG; cytochrome c biogenesis protein CcmG, thiol:disulfide interchange protein DsbE" } ] }, { "name":"04131 Membrane trafficking [BR:cvb04131]", "children":[ { "name":"R0135_00965 ndk; (GenBank) nucleoside-diphosphate kinase\tK00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]" }, { "name":"R0135_00840 class I fructose-bisphosphate aldolase\tK01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]" }, { "name":"R0135_03490 glyceraldehyde-3-phosphate dehydrogenase\tK00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]" }, { "name":"R0135_05170 gap; (GenBank) type I glyceraldehyde-3-phosphate dehydrogenase\tK00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]" }, { "name":"R0135_05470 gap; (GenBank) type I glyceraldehyde-3-phosphate dehydrogenase\tK00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]" }, { "name":"R0135_05475 glyceraldehyde 3-phosphate dehydrogenase NAD-binding domain-containing protein\tK00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]" }, { "name":"R0135_11045 pyk; (GenBank) pyruvate kinase\tK00873 PK; pyruvate kinase [EC:2.7.1.40]" }, { "name":"R0135_02285 htpG; (GenBank) molecular chaperone HtpG\tK04079 HSP90A; molecular chaperone HtpG" } ] }, { "name":"04121 Ubiquitin system" }, { "name":"03051 Proteasome [BR:cvb03051]", "children":[ { "name":"R0135_02285 htpG; (GenBank) molecular chaperone HtpG\tK04079 HSP90A; molecular chaperone HtpG" } ] }, { "name":"03032 DNA replication proteins [BR:cvb03032]", "children":[ { "name":"R0135_02930 rnhA; (GenBank) ribonuclease HI\tK03469 rnhA; ribonuclease HI [EC:3.1.26.4]" }, { "name":"R0135_14175 DNA cytosine methyltransferase\tK00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]" }, { "name":"R0135_03040 HU family DNA-binding protein\tK03530 hupB; DNA-binding protein HU-beta" }, { "name":"R0135_06065 ihfA; (GenBank) integration host factor subunit alpha\tK04764 ihfA; integration host factor subunit alpha" }, { "name":"R0135_06780 ihfB; (GenBank) integration host factor subunit beta\tK05788 ihfB; integration host factor subunit beta" }, { "name":"R0135_11745 dnaA; (GenBank) chromosomal replication initiator protein DnaA\tK02313 dnaA; chromosomal replication initiator protein" }, { "name":"R0135_15390 dnaB; (GenBank) replicative DNA helicase\tK02314 dnaB; replicative DNA helicase [EC:5.6.2.3]" }, { "name":"R0135_14330 dnaG; (GenBank) DNA primase\tK02316 dnaG; DNA primase [EC:2.7.7.101]" }, { "name":"R0135_15880 ssb; (GenBank) single-stranded DNA-binding protein\tK03111 ssb; single-strand DNA-binding protein" }, { "name":"R0135_00100 dnaE; (GenBank) DNA polymerase III subunit alpha\tK02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]" }, { "name":"R0135_11750 dnaN; (GenBank) DNA polymerase III subunit beta\tK02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]" }, { "name":"R0135_01620 DNA polymerase III subunit chi\tK02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7]" }, { "name":"R0135_08410 holA; (GenBank) DNA polymerase III subunit delta\tK02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]" }, { "name":"R0135_03080 DNA polymerase III subunit delta'\tK02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]" }, { "name":"R0135_01445 3'-5' exonuclease\tK02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]" }, { "name":"R0135_02925 dnaQ; (GenBank) DNA polymerase III subunit epsilon\tK02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]" }, { "name":"R0135_03595 dnaX; (GenBank) DNA polymerase III subunit gamma\/tau\tK02343 dnaX; DNA polymerase III subunit gamma\/tau [EC:2.7.7.7]" }, { "name":"R0135_00095 rnhB; (GenBank) ribonuclease HII\tK03470 rnhB; ribonuclease HII [EC:3.1.26.4]" }, { "name":"R0135_11995 polA; (GenBank) DNA polymerase I\tK02335 polA; DNA polymerase I [EC:2.7.7.7]" }, { "name":"R0135_02180 ligA; (GenBank) NAD-dependent DNA ligase LigA\tK01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]" }, { "name":"R0135_17435 hda; (GenBank) DnaA regulatory inactivator Hda\tK10763 hda; DnaA-homolog protein" }, { "name":"R0135_06815 gyrA; (GenBank) DNA gyrase subunit A\tK02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]" }, { "name":"R0135_11760 gyrB; (GenBank) DNA topoisomerase (ATP-hydrolyzing) subunit B\tK02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]" }, { "name":"R0135_12475 parC; (GenBank) DNA topoisomerase IV subunit A\tK02621 parC; topoisomerase IV subunit A [EC:5.6.2.2]" }, { "name":"R0135_12170 parE; (GenBank) DNA topoisomerase IV subunit B\tK02622 parE; topoisomerase IV subunit B [EC:5.6.2.2]" }, { "name":"R0135_03535 topA; (GenBank) type I DNA topoisomerase\tK03168 topA; DNA topoisomerase I [EC:5.6.2.1]" } ] }, { "name":"03036 Chromosome and associated proteins [BR:cvb03036]", "children":[ { "name":"R0135_14175 DNA cytosine methyltransferase\tK00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]" }, { "name":"R0135_01815 rnc; (GenBank) ribonuclease III\tK03685 rnc; ribonuclease III [EC:3.1.26.3]" }, { "name":"R0135_00840 class I fructose-bisphosphate aldolase\tK01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]" }, { "name":"R0135_03040 HU family DNA-binding protein\tK03530 hupB; DNA-binding protein HU-beta" }, { "name":"R0135_06065 ihfA; (GenBank) integration host factor subunit alpha\tK04764 ihfA; integration host factor subunit alpha" }, { "name":"R0135_06780 ihfB; (GenBank) integration host factor subunit beta\tK05788 ihfB; integration host factor subunit beta" }, { "name":"R0135_00880 DnaJ C-terminal domain-containing protein\tK05516 cbpA; curved DNA-binding protein" }, { "name":"R0135_00875 chaperone modulator CbpM\tK18997 cbpM; chaperone modulatory protein CbpM" }, { "name":"R0135_11745 dnaA; (GenBank) chromosomal replication initiator protein DnaA\tK02313 dnaA; chromosomal replication initiator protein" }, { "name":"R0135_16320 Dps family protein\tK04047 dps; starvation-inducible DNA-binding protein" }, { "name":"R0135_14565 fis; (GenBank) DNA-binding transcriptional regulator Fis\tK03557 fis; Fis family transcriptional regulator, factor for inversion stimulation protein" }, { "name":"R0135_14970 hfq; (GenBank) RNA chaperone Hfq\tK03666 hfq; host factor-I protein" }, { "name":"R0135_04805 Lrp\/AsnC family transcriptional regulator\tK03719 lrp; Lrp\/AsnC family transcriptional regulator, leucine-responsive regulatory protein" }, { "name":"R0135_12040 Lrp\/AsnC family transcriptional regulator\tK03719 lrp; Lrp\/AsnC family transcriptional regulator, leucine-responsive regulatory protein" }, { "name":"R0135_02170 smc; (GenBank) chromosome segregation protein SMC\tK03529 smc; chromosome segregation protein" }, { "name":"R0135_06850 ScpA family protein\tK05896 scpA; segregation and condensation protein A" }, { "name":"R0135_06845 scpB; (GenBank) SMC-Scp complex subunit ScpB\tK06024 scpB; segregation and condensation protein B" }, { "name":"R0135_07195 ftsA; (GenBank) cell division protein FtsA\tK03590 ftsA; cell division protein FtsA" }, { "name":"R0135_05385 ftsB; (GenBank) cell division protein FtsB\tK05589 ftsB; cell division protein FtsB" }, { "name":"R0135_11425 ftsE; (GenBank) cell division ATP-binding protein FtsE\tK09812 ftsE; cell division transport system ATP-binding protein" }, { "name":"R0135_07245 penicillin-binding protein 2\tK03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4]" }, { "name":"R0135_02660 DNA translocase FtsK 4TM domain-containing protein\tK03466 ftsK; DNA segregation ATPase FtsK\/SpoIIIE, S-DNA-T family" }, { "name":"R0135_07250 ftsL; (GenBank) cell division protein FtsL\tK03586 ftsL; cell division protein FtsL" }, { "name":"R0135_07200 FtsQ-type POTRA domain-containing protein\tK03589 ftsQ; cell division protein FtsQ" }, { "name":"R0135_07220 ftsW; (GenBank) putative lipid II flippase FtsW\tK03588 ftsW; peptidoglycan glycosyltransferase [EC:2.4.99.28]" }, { "name":"R0135_11420 ftsX; (GenBank) permease-like cell division protein FtsX\tK09811 ftsX; cell division transport system permease protein" }, { "name":"R0135_07190 ftsZ; (GenBank) cell division protein FtsZ\tK03531 ftsZ; cell division protein FtsZ" }, { "name":"R0135_02175 zipA; (GenBank) cell division protein ZipA\tK03528 zipA; cell division protein ZipA" }, { "name":"R0135_11210 cell division protein ZapA\tK09888 zapA; cell division protein ZapA" }, { "name":"R0135_11205 zapB; (GenBank) cell division protein ZapB\tK09892 zapB; cell division protein ZapB" }, { "name":"R0135_07325 zapE; (GenBank) cell division protein ZapE\tK06916 zapE; cell division protein ZapE" }, { "name":"R0135_14955 N-acetylmuramoyl-L-alanine amidase\tK01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]" }, { "name":"R0135_01530 efflux RND transporter periplasmic adaptor subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system" }, { "name":"R0135_05670 efflux RND transporter periplasmic adaptor subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system" }, { "name":"R0135_09045 efflux RND transporter periplasmic adaptor subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system" }, { "name":"R0135_09575 efflux RND transporter periplasmic adaptor subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system" }, { "name":"R0135_12680 efflux RND transporter periplasmic adaptor subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system" }, { "name":"R0135_11485 slmA; (GenBank) nucleoid occlusion factor SlmA\tK05501 slmA; TetR\/AcrR family transcriptional regulator" }, { "name":"R0135_07460 rod shape-determining protein\tK03569 mreB; rod shape-determining protein MreB and related proteins" }, { "name":"R0135_07455 mreC; (GenBank) rod shape-determining protein MreC\tK03570 mreC; rod shape-determining protein MreC" }, { "name":"R0135_07450 mreD; (GenBank) rod shape-determining protein MreD\tK03571 mreD; rod shape-determining protein MreD" }, { "name":"R0135_09315 rodA; (GenBank) rod shape-determining protein RodA\tK05837 rodA; peptidoglycan glycosyltransferase [EC:2.4.99.28]" }, { "name":"R0135_11705 ParA family protein\tK03496 parA; chromosome partitioning protein" }, { "name":"R0135_14895 ParA family protein\tK03496 parA; chromosome partitioning protein" }, { "name":"R0135_11700 ParB\/RepB\/Spo0J family partition protein\tK03497 parB; ParB family transcriptional regulator, chromosome partitioning protein" }, { "name":"R0135_12475 parC; (GenBank) DNA topoisomerase IV subunit A\tK02621 parC; topoisomerase IV subunit A [EC:5.6.2.2]" }, { "name":"R0135_12170 parE; (GenBank) DNA topoisomerase IV subunit B\tK02622 parE; topoisomerase IV subunit B [EC:5.6.2.2]" }, { "name":"R0135_11715 mnmG; (GenBank) tRNA uridine-5-carboxymethylaminomethyl(34) synthesis enzyme MnmG\tK03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme" }, { "name":"R0135_11710 rsmG; (GenBank) 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG\tK03501 gidB; 16S rRNA (guanine527-N7)-methyltransferase [EC:2.1.1.170]" }, { "name":"R0135_09690 xerC; (GenBank) tyrosine recombinase XerC\tK03733 xerC; integrase\/recombinase XerC" }, { "name":"R0135_00760 xerD; (GenBank) site-specific tyrosine recombinase XerD\tK04763 xerD; integrase\/recombinase XerD" }, { "name":"R0135_17400 apbC; (GenBank) iron-sulfur cluster carrier protein ApbC\tK03593 mrp; ATP-binding protein involved in chromosome partitioning" }, { "name":"R0135_12000 yihA; (GenBank) ribosome biogenesis GTP-binding protein YihA\/YsxC\tK03978 engB; GTP-binding protein" } ] }, { "name":"03400 DNA repair and recombination proteins [BR:cvb03400]", "children":[ { "name":"R0135_03285 deoxyribodipyrimidine photo-lyase\tK01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]" }, { "name":"R0135_10200 deoxyribodipyrimidine photo-lyase\tK01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]" }, { "name":"R0135_01750 ung; (GenBank) uracil-DNA glycosylase\tK03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]" }, { "name":"R0135_12355 mutY; (GenBank) A\/G-specific adenine glycosylase\tK03575 mutY; A\/G-specific adenine glycosylase [EC:3.2.2.31]" }, { "name":"R0135_14170 hypothetical protein\tK03575 mutY; A\/G-specific adenine glycosylase [EC:3.2.2.31]" }, { "name":"R0135_00005 nth; (GenBank) endonuclease III\tK10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]" }, { "name":"R0135_03975 S1\/P1 nuclease\tK05986 NUCS; nuclease S1 [EC:3.1.30.1]" }, { "name":"R0135_07170 mutT; (GenBank) 8-oxo-dGTP diphosphatase MutT\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]" }, { "name":"R0135_06005 methylated-DNA--[protein]-cysteine S-methyltransferase\tK10778 ada; AraC family transcriptional regulator, regulatory protein of adaptative response \/ methylated-DNA-[protein]-cysteine methyltransferase [EC:2.1.1.63]" }, { "name":"R0135_16035 cryptochrome\/photolyase family protein\tK06876 phrB; (6-4)DNA photolyase [EC:4.1.99.13]" }, { "name":"R0135_09860 DNA-3-methyladenine glycosylase 2 family protein\tK01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]" }, { "name":"R0135_16690 DNA-3-methyladenine glycosylase I\tK01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]" }, { "name":"R0135_11450 mutM; (GenBank) bifunctional DNA-formamidopyrimidine glycosylase\/DNA-(apurinic or apyrimidinic site) lyase\tK10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]" }, { "name":"R0135_10845 nei; (GenBank) endonuclease VIII\tK05522 nei; endonuclease VIII [EC:3.2.2.- 4.2.99.18]" }, { "name":"R0135_02525 exodeoxyribonuclease III\tK01142 xthA; exodeoxyribonuclease III [EC:3.1.11.2]" }, { "name":"R0135_11500 exodeoxyribonuclease III\tK01142 xthA; exodeoxyribonuclease III [EC:3.1.11.2]" }, { "name":"R0135_15155 nfo; (GenBank) deoxyribonuclease IV\tK01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]" }, { "name":"R0135_00785 recJ; (GenBank) single-stranded-DNA-specific exonuclease RecJ\tK07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]" }, { "name":"R0135_02180 ligA; (GenBank) NAD-dependent DNA ligase LigA\tK01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]" }, { "name":"R0135_11995 polA; (GenBank) DNA polymerase I\tK02335 polA; DNA polymerase I [EC:2.7.7.7]" }, { "name":"R0135_15870 uvrA; (GenBank) excinuclease ABC subunit UvrA\tK03701 uvrA; excinuclease ABC subunit A" }, { "name":"R0135_06105 uvrB; (GenBank) excinuclease ABC subunit UvrB\tK03702 uvrB; excinuclease ABC subunit B" }, { "name":"R0135_03395 uvrC; (GenBank) excinuclease ABC subunit UvrC\tK03703 uvrC; excinuclease ABC subunit C" }, { "name":"R0135_10195 GIY-YIG nuclease family protein\tK05984 cho; excinuclease Cho [EC:3.1.25.-]" }, { "name":"R0135_11605 uvrD; (GenBank) DNA helicase II\tK03657 uvrD; ATP-dependent DNA helicase UvrD\/PcrA [EC:5.6.2.4]" }, { "name":"R0135_15680 rpoB; (GenBank) DNA-directed RNA polymerase subunit beta\tK03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]" }, { "name":"R0135_15685 rpoC; (GenBank) DNA-directed RNA polymerase subunit beta'\tK03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]" }, { "name":"R0135_15860 rpoA; (GenBank) DNA-directed RNA polymerase subunit alpha\tK03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]" }, { "name":"R0135_11520 rpoZ; (GenBank) DNA-directed RNA polymerase subunit omega\tK03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]" }, { "name":"R0135_03495 mfd; (GenBank) transcription-repair coupling factor\tK03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]" }, { "name":"R0135_05345 mutS; (GenBank) DNA mismatch repair protein MutS\tK03555 mutS; DNA mismatch repair protein MutS" }, { "name":"R0135_14960 mutL; (GenBank) DNA mismatch repair endonuclease MutL\tK03572 mutL; DNA mismatch repair protein MutL" }, { "name":"R0135_16955 sbcB; (GenBank) exodeoxyribonuclease I\tK01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]" }, { "name":"R0135_00825 xseA; (GenBank) exodeoxyribonuclease VII large subunit\tK03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]" }, { "name":"R0135_00100 dnaE; (GenBank) DNA polymerase III subunit alpha\tK02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]" }, { "name":"R0135_11750 dnaN; (GenBank) DNA polymerase III subunit beta\tK02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]" }, { "name":"R0135_01620 DNA polymerase III subunit chi\tK02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7]" }, { "name":"R0135_08410 holA; (GenBank) DNA polymerase III subunit delta\tK02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]" }, { "name":"R0135_03080 DNA polymerase III subunit delta'\tK02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]" }, { "name":"R0135_01445 3'-5' exonuclease\tK02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]" }, { "name":"R0135_02925 dnaQ; (GenBank) DNA polymerase III subunit epsilon\tK02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]" }, { "name":"R0135_03595 dnaX; (GenBank) DNA polymerase III subunit gamma\/tau\tK02343 dnaX; DNA polymerase III subunit gamma\/tau [EC:2.7.7.7]" }, { "name":"R0135_15880 ssb; (GenBank) single-stranded DNA-binding protein\tK03111 ssb; single-strand DNA-binding protein" }, { "name":"R0135_05330 recA; (GenBank) recombinase RecA\tK03553 recA; recombination protein RecA" }, { "name":"R0135_09215 ruvA; (GenBank) Holliday junction branch migration protein RuvA\tK03550 ruvA; holliday junction DNA helicase RuvA" }, { "name":"R0135_09210 ruvB; (GenBank) Holliday junction branch migration DNA helicase RuvB\tK03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]" }, { "name":"R0135_09220 ruvC; (GenBank) crossover junction endodeoxyribonuclease RuvC\tK01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]" }, { "name":"R0135_12660 primosomal protein N'\tK04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]" }, { "name":"R0135_15410 radA; (GenBank) DNA repair protein RadA\tK04485 radA; DNA repair protein RadA\/Sms" }, { "name":"R0135_11755 recF; (GenBank) DNA replication\/repair protein RecF\tK03629 recF; DNA replication and repair protein RecF" }, { "name":"R0135_11540 recG; (GenBank) ATP-dependent DNA helicase RecG\tK03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]" }, { "name":"R0135_14200 ATP-binding protein\tK03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]" }, { "name":"R0135_01825 recO; (GenBank) DNA repair protein RecO\tK03584 recO; DNA repair protein RecO (recombination protein O)" }, { "name":"R0135_03585 recR; (GenBank) recombination mediator RecR\tK06187 recR; recombination protein RecR" }, { "name":"R0135_16615 recN; (GenBank) DNA repair protein RecN\tK03631 recN; DNA repair protein RecN (Recombination protein N)" }, { "name":"R0135_12245 recombination-associated protein RdgC\tK03554 rdgC; recombination associated protein RdgC" }, { "name":"R0135_02030 helicase HerA-like domain-containing protein\tK06915 herA; DNA double-strand break repair helicase HerA and related ATPase" }, { "name":"R0135_06815 gyrA; (GenBank) DNA gyrase subunit A\tK02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]" }, { "name":"R0135_11760 gyrB; (GenBank) DNA topoisomerase (ATP-hydrolyzing) subunit B\tK02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]" }, { "name":"R0135_03535 topA; (GenBank) type I DNA topoisomerase\tK03168 topA; DNA topoisomerase I [EC:5.6.2.1]" }, { "name":"R0135_03040 HU family DNA-binding protein\tK03530 hupB; DNA-binding protein HU-beta" }, { "name":"R0135_14565 fis; (GenBank) DNA-binding transcriptional regulator Fis\tK03557 fis; Fis family transcriptional regulator, factor for inversion stimulation protein" }, { "name":"R0135_06065 ihfA; (GenBank) integration host factor subunit alpha\tK04764 ihfA; integration host factor subunit alpha" }, { "name":"R0135_06780 ihfB; (GenBank) integration host factor subunit beta\tK05788 ihfB; integration host factor subunit beta" }, { "name":"R0135_06680 recQ; (GenBank) DNA helicase RecQ\tK03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]" }, { "name":"R0135_05250 dinB; (GenBank) DNA polymerase IV\tK02346 dinB; DNA polymerase IV [EC:2.7.7.7]" }, { "name":"R0135_03520 lexA; (GenBank) transcriptional repressor LexA\tK01356 lexA; repressor LexA [EC:3.4.21.88]" }, { "name":"R0135_08420 imuA; (GenBank) translesion DNA synthesis-associated protein ImuA\tK14160 imuA; protein ImuA" }, { "name":"R0135_08435 DNA polymerase Y family protein\tK14161 imuB; protein ImuB" }, { "name":"R0135_08505 error-prone DNA polymerase\tK14162 dnaE2; error-prone DNA polymerase [EC:2.7.7.7]" }, { "name":"R0135_05325 regulatory protein RecX\tK03565 recX; regulatory protein" }, { "name":"R0135_09425 dinG; (GenBank) ATP-dependent DNA helicase DinG\tK03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]" }, { "name":"R0135_09370 ribonucleoside-diphosphate reductase subunit alpha\tK00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]" }, { "name":"R0135_09375 ribonucleotide-diphosphate reductase subunit beta\tK00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]" } ] }, { "name":"03029 Mitochondrial biogenesis [BR:cvb03029]", "children":[ { "name":"R0135_07305 ubiquinol-cytochrome c reductase\tK00412 CYTB; ubiquinol-cytochrome c reductase cytochrome b subunit" }, { "name":"R0135_08685 infB; (GenBank) translation initiation factor IF-2\tK02519 infB; translation initiation factor IF-2" }, { "name":"R0135_06090 infC; (GenBank) translation initiation factor IF-3\tK02520 infC; translation initiation factor IF-3" }, { "name":"R0135_00030 tsf; (GenBank) translation elongation factor Ts\tK02357 tsf; elongation factor Ts" }, { "name":"R0135_15640 tuf; (GenBank) elongation factor Tu\tK02358 tuf; elongation factor Tu" }, { "name":"R0135_15710 tuf; (GenBank) elongation factor Tu\tK02358 tuf; elongation factor Tu" }, { "name":"R0135_09815 fusA; (GenBank) elongation factor G\tK02355 fusA; elongation factor G" }, { "name":"R0135_15705 fusA; (GenBank) elongation factor G\tK02355 fusA; elongation factor G" }, { "name":"R0135_01820 era; (GenBank) GTPase Era\tK03595 era; GTPase" }, { "name":"R0135_14685 tyrS; (GenBank) tyrosine--tRNA ligase\tK01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]" }, { "name":"R0135_08400 leuS; (GenBank) leucine--tRNA ligase\tK01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]" }, { "name":"R0135_09230 aspS; (GenBank) aspartate--tRNA ligase\tK01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]" }, { "name":"R0135_12655 argS; (GenBank) arginine--tRNA ligase\tK01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]" }, { "name":"R0135_07470 gatA; (GenBank) Asp-tRNA(Asn)\/Glu-tRNA(Gln) amidotransferase subunit GatA\tK02433 gatA; aspartyl-tRNA(Asn)\/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7]" }, { "name":"R0135_07475 gatB; (GenBank) Asp-tRNA(Asn)\/Glu-tRNA(Gln) amidotransferase subunit GatB\tK02434 gatB; aspartyl-tRNA(Asn)\/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7]" }, { "name":"R0135_07465 gatC; (GenBank) Asp-tRNA(Asn)\/Glu-tRNA(Gln) amidotransferase subunit GatC\tK02435 gatC; aspartyl-tRNA(Asn)\/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7]" }, { "name":"R0135_15880 ssb; (GenBank) single-stranded DNA-binding protein\tK03111 ssb; single-strand DNA-binding protein" }, { "name":"R0135_00065 bamA; (GenBank) outer membrane protein assembly factor BamA\tK07277 SAM50; outer membrane protein insertion porin family" }, { "name":"R0135_16630 dnaK; (GenBank) molecular chaperone DnaK\tK04043 dnaK; molecular chaperone DnaK" }, { "name":"R0135_16625 grpE; (GenBank) nucleotide exchange factor GrpE\tK03687 GRPE; molecular chaperone GrpE" }, { "name":"R0135_16930 groL; (GenBank) chaperonin GroEL\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]" }, { "name":"R0135_16925 co-chaperone GroES\tK04078 groES; chaperonin GroES" }, { "name":"R0135_16635 dnaJ; (GenBank) molecular chaperone DnaJ\tK03686 dnaJ; molecular chaperone DnaJ" }, { "name":"R0135_00960 IscS subfamily cysteine desulfurase\tK04487 iscS; cysteine desulfurase [EC:2.8.1.7]" }, { "name":"R0135_09355 grxD; (GenBank) Grx4 family monothiol glutaredoxin\tK07390 grxD; monothiol glutaredoxin" }, { "name":"R0135_17400 apbC; (GenBank) iron-sulfur cluster carrier protein ApbC\tK03593 mrp; ATP-binding protein involved in chromosome partitioning" }, { "name":"R0135_11985 cyoE; (GenBank) heme o synthase\tK02257 COX10; heme o synthase [EC:2.5.1.141]" }, { "name":"R0135_11960 cytochrome c oxidase assembly protein\tK02258 COX11; cytochrome c oxidase assembly protein subunit 11" }, { "name":"R0135_08310 COX15\/CtaA family protein\tK02259 COX15; heme a synthase [EC:1.17.99.9]" }, { "name":"R0135_11725 yidC; (GenBank) membrane protein insertase YidC\tK03217 yidC; YidC\/Oxa1 family membrane protein insertase" }, { "name":"R0135_11975 SURF1 family protein\tK14998 SURF1; surfeit locus 1 family protein" }, { "name":"R0135_10670 SCO family protein\tK07152 SCO1; protein SCO1" }, { "name":"R0135_11990 SCO family protein\tK07152 SCO1; protein SCO1" }, { "name":"R0135_02285 htpG; (GenBank) molecular chaperone HtpG\tK04079 HSP90A; molecular chaperone HtpG" } ] } ] }, { "name":"09183 Protein families: signaling and cellular processes", "children":[ { "name":"02000 Transporters [BR:cvb02000]", "children":[ { "name":"R0135_05570 msbA; (GenBank) lipid A export permease\/ATP-binding protein MsbA\tK11085 msbA; ATP-binding cassette, subfamily B, bacterial MsbA [EC:7.5.2.6]" }, { "name":"R0135_03795 ABC transporter ATP-binding protein\tK18888 efrB; ATP-binding cassette, subfamily B, multidrug efflux pump" }, { "name":"R0135_05525 ABC transporter ATP-binding protein\/permease\tK24821 atm1; ATP-binding cassette, subfamily B, heavy metal transporter" }, { "name":"R0135_09595 ABC transporter ATP-binding protein\tK18893 vcaM; ATP-binding cassette, subfamily B, multidrug efflux pump" }, { "name":"R0135_12585 ABC transporter transmembrane domain-containing protein\tK06147 ABCB-BAC; ATP-binding cassette, subfamily B, bacterial" }, { "name":"R0135_07615 type I secretion system permease\/ATPase\tK12541 lapB; ATP-binding cassette, subfamily C, bacterial LapB" }, { "name":"R0135_08330 ATP-binding cassette domain-containing protein\tK15738 uup; ABC transport system ATP-binding\/permease protein" }, { "name":"R0135_12775 modA; (GenBank) molybdate ABC transporter substrate-binding protein\tK02020 modA; molybdate transport system substrate-binding protein" }, { "name":"R0135_12770 modB; (GenBank) molybdate ABC transporter permease subunit\tK02018 modB; molybdate transport system permease protein" }, { "name":"R0135_12765 modC; (GenBank) molybdenum ABC transporter ATP-binding protein\tK02017 modC; molybdate transport system ATP-binding protein [EC:7.3.2.5]" }, { "name":"R0135_14630 ATP-binding cassette domain-containing protein\tK05776 modF; molybdate transport system ATP-binding protein" }, { "name":"R0135_07965 extracellular solute-binding protein\tK02055 ABC.SP.S; putative spermidine\/putrescine transport system substrate-binding protein" }, { "name":"R0135_13290 glycine betaine ABC transporter substrate-binding protein\tK05845 opuC; osmoprotectant transport system substrate-binding protein" }, { "name":"R0135_13285 ATP-binding cassette domain-containing protein\tK05847 opuA; osmoprotectant transport system ATP-binding protein [EC:7.6.2.9]" }, { "name":"R0135_04985 ABC transporter substrate-binding protein\tK17321 glpV; glycerol transport system substrate-binding protein" }, { "name":"R0135_04970 sugar ABC transporter permease\tK17322 glpP; glycerol transport system permease protein" }, { "name":"R0135_04975 carbohydrate ABC transporter permease\tK17323 glpQ; glycerol transport system permease protein" }, { "name":"R0135_04960 ABC transporter ATP-binding protein\tK17324 glpS; glycerol transport system ATP-binding protein" }, { "name":"R0135_04965 ABC transporter ATP-binding protein\tK17325 glpT; glycerol transport system ATP-binding protein" }, { "name":"R0135_17510 MlaD family protein\tK02067 mlaD; phospholipid\/cholesterol\/gamma-HCH transport system substrate-binding protein" }, { "name":"R0135_17520 ABC transporter permease\tK02066 mlaE; phospholipid\/cholesterol\/gamma-HCH transport system permease protein" }, { "name":"R0135_17515 ATP-binding cassette domain-containing protein\tK02065 mlaF; phospholipid\/cholesterol\/gamma-HCH transport system ATP-binding protein" }, { "name":"R0135_07365 ABC transporter substrate-binding protein\tK07323 mlaC; phospholipid transport system substrate-binding protein" }, { "name":"R0135_02200 phosphate ABC transporter substrate-binding protein\tK02040 pstS; phosphate transport system substrate-binding protein" }, { "name":"R0135_02205 ABC transporter permease subunit\tK02037 pstC; phosphate transport system permease protein" }, { "name":"R0135_02210 pstA; (GenBank) phosphate ABC transporter permease PstA\tK02038 pstA; phosphate transport system permease protein" }, { "name":"R0135_02215 pstB; (GenBank) phosphate ABC transporter ATP-binding protein PstB\tK02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1]" }, { "name":"R0135_05235 urtA; (GenBank) urea ABC transporter substrate-binding protein\tK11959 urtA; urea transport system substrate-binding protein" }, { "name":"R0135_05230 urtB; (GenBank) urea ABC transporter permease subunit UrtB\tK11960 urtB; urea transport system permease protein" }, { "name":"R0135_05225 urtC; (GenBank) urea ABC transporter permease subunit UrtC\tK11961 urtC; urea transport system permease protein" }, { "name":"R0135_05220 urtD; (GenBank) urea ABC transporter ATP-binding protein UrtD\tK11962 urtD; urea transport system ATP-binding protein" }, { "name":"R0135_05215 urtE; (GenBank) urea ABC transporter ATP-binding subunit UrtE\tK11963 urtE; urea transport system ATP-binding protein" }, { "name":"R0135_16575 transporter substrate-binding domain-containing protein\tK02030 ABC.PA.S; polar amino acid transport system substrate-binding protein" }, { "name":"R0135_09930 peptide ABC transporter substrate-binding protein\tK15580 oppA; oligopeptide transport system substrate-binding protein" }, { "name":"R0135_09935 peptide ABC transporter substrate-binding protein\tK15580 oppA; oligopeptide transport system substrate-binding protein" }, { "name":"R0135_09940 ABC transporter permease subunit\tK15581 oppB; oligopeptide transport system permease protein" }, { "name":"R0135_09945 ABC transporter permease\tK15582 oppC; oligopeptide transport system permease protein" }, { "name":"R0135_16465 ABC transporter ATP-binding protein\tK02031 ddpD; peptide\/nickel transport system ATP-binding protein" }, { "name":"R0135_16460 ATP-binding cassette domain-containing protein\tK02032 ddpF; peptide\/nickel transport system ATP-binding protein" }, { "name":"R0135_16470 ABC transporter substrate-binding protein\tK13893 yejA; microcin C transport system substrate-binding protein" }, { "name":"R0135_16480 ABC transporter permease\tK13894 yejB; microcin C transport system permease protein" }, { "name":"R0135_16475 ABC transporter permease subunit\tK13895 yejE; microcin C transport system permease protein" }, { "name":"R0135_09950 dipeptide ABC transporter ATP-binding protein\tK13896 yejF; microcin C transport system ATP-binding protein" }, { "name":"R0135_01345 iron ABC transporter permease\tK25133 hmuU; heme transport system permease protein" }, { "name":"R0135_01340 ATP-binding cassette domain-containing protein\tK10834 hmuV; heme transport system ATP-binding protein [EC:7.6.2.5]" }, { "name":"R0135_01335 helical backbone metal receptor\tK02016 ABC.FEV.S; iron complex transport system substrate-binding protein" }, { "name":"R0135_14390 ABC transporter ATP-binding protein\tK09691 wzt; homopolymeric O-antigen transport system ATP-binding protein [EC:7.5.2.14]" }, { "name":"R0135_01630 lptF; (GenBank) LPS export ABC transporter permease LptF\tK07091 lptF; lipopolysaccharide export system permease protein" }, { "name":"R0135_01635 lptG; (GenBank) LPS export ABC transporter permease LptG\tK11720 lptG; lipopolysaccharide export system permease protein" }, { "name":"R0135_07395 lptB; (GenBank) LPS export ABC transporter ATP-binding protein\tK06861 lptB; lipopolysaccharide export system ATP-binding protein [EC:7.5.2.5]" }, { "name":"R0135_14385 ABC transporter permease\tK09692 tagG; teichoic acid transport system permease protein" }, { "name":"R0135_10885 ABC transporter ATP-binding protein\tK25152 gldA; gliding motility-associated transport system ATP-binding protein" }, { "name":"R0135_03435 FtsX-like permease family protein\tK09808 lolC_E_F; lipoprotein-releasing system permease protein" }, { "name":"R0135_03445 lipoprotein-releasing ABC transporter permease subunit\tK09808 lolC_E_F; lipoprotein-releasing system permease protein" }, { "name":"R0135_03440 lolD; (GenBank) lipoprotein-releasing ABC transporter ATP-binding protein LolD\tK09810 lolD; lipoprotein-releasing system ATP-binding protein [EC:7.6.2.-]" }, { "name":"R0135_02140 ccmD; (GenBank) heme exporter protein CcmD\tK02196 ccmD; heme exporter protein D" }, { "name":"R0135_02135 heme ABC transporter permease\tK02195 ccmC; heme exporter protein C" }, { "name":"R0135_02130 ccmB; (GenBank) heme exporter protein CcmB\tK02194 ccmB; heme exporter protein B" }, { "name":"R0135_02125 ccmA; (GenBank) cytochrome c biogenesis heme-transporting ATPase CcmA\tK02193 ccmA; heme exporter protein A [EC:7.6.2.5]" }, { "name":"R0135_11420 ftsX; (GenBank) permease-like cell division protein FtsX\tK09811 ftsX; cell division transport system permease protein" }, { "name":"R0135_11425 ftsE; (GenBank) cell division ATP-binding protein FtsE\tK09812 ftsE; cell division transport system ATP-binding protein" }, { "name":"R0135_02365 ABC transporter permease\tK01992 ABC-2.P; ABC-2 type transport system permease protein" }, { "name":"R0135_01025 ABC transporter ATP-binding protein\tK01990 ABC-2.A; ABC-2 type transport system ATP-binding protein" }, { "name":"R0135_02360 ABC transporter ATP-binding protein\tK01990 ABC-2.A; ABC-2 type transport system ATP-binding protein" }, { "name":"R0135_02105 FtsX-like permease family protein\tK02004 ABC.CD.P; putative ABC transport system permease protein" }, { "name":"R0135_06325 FtsX-like permease family protein\tK02004 ABC.CD.P; putative ABC transport system permease protein" }, { "name":"R0135_06330 ABC transporter permease\tK02004 ABC.CD.P; putative ABC transport system permease protein" }, { "name":"R0135_02100 ABC transporter ATP-binding protein\tK02003 ABC.CD.A; putative ABC transport system ATP-binding protein" }, { "name":"R0135_06320 ABC transporter ATP-binding protein\tK02003 ABC.CD.A; putative ABC transport system ATP-binding protein" }, { "name":"R0135_10340 ABC transporter ATP-binding protein\tK02003 ABC.CD.A; putative ABC transport system ATP-binding protein" }, { "name":"R0135_10010 sufC; (GenBank) Fe-S cluster assembly ATPase SufC\tK09013 sufC; Fe-S cluster assembly ATP-binding protein" }, { "name":"R0135_02885 DASS family sodium-coupled anion symporter\tK14445 SLC13A2_3_5; solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2\/3\/5" }, { "name":"R0135_09540 SLC13 family permease\tK14445 SLC13A2_3_5; solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2\/3\/5" }, { "name":"R0135_02065 MATE family efflux transporter\tK26939 norM; MATE family, multidrug efflux pump" }, { "name":"R0135_09270 MATE family efflux transporter\tK26937 dinF; MATE family, multidrug efflux pump" }, { "name":"R0135_11945 MATE family efflux transporter\tK26937 dinF; MATE family, multidrug efflux pump" }, { "name":"R0135_15060 MATE family efflux transporter\tK26937 dinF; MATE family, multidrug efflux pump" }, { "name":"R0135_13070 tsgA; (GenBank) MFS transporter TsgA\tK06141 tsgA; MFS transporter, TsgA protein" }, { "name":"R0135_10585 MFS transporter\tK08191 exuT; MFS transporter, ACS family, aldohexuronate transporter" }, { "name":"R0135_13330 PucC family protein\tK08226 pucC; MFS transporter, BCD family, chlorophyll transporter" }, { "name":"R0135_17265 BCD family MFS transporter\tK08226 pucC; MFS transporter, BCD family, chlorophyll transporter" }, { "name":"R0135_17310 BCD family MFS transporter\tK08226 pucC; MFS transporter, BCD family, chlorophyll transporter" }, { "name":"R0135_16910 AmpG family muropeptide MFS transporter\tK08218 ampG; MFS transporter, PAT family, beta-lactamase induction signal transducer AmpG" }, { "name":"R0135_12030 multidrug effflux MFS transporter\tK07552 bcr; MFS transporter, DHA1 family, multidrug resistance protein" }, { "name":"R0135_11165 ptsP; (GenBank) phosphoenolpyruvate--protein phosphotransferase\tK08484 ptsP; phosphotransferase system, enzyme I, PtsP [EC:2.7.3.9]" }, { "name":"R0135_07420 HPr family phosphocarrier protein\tK08485 ptsO; phosphocarrier protein NPr" }, { "name":"R0135_07410 PTS sugar transporter subunit IIA\tK02806 ptsN; nitrogen PTS system EIIA component [EC:2.7.1.-]" }, { "name":"R0135_02090 ion transporter\tK10716 kch; voltage-gated potassium channel" }, { "name":"R0135_09760 ammonium transporter\tK03320 amt; ammonium transporter, Amt family" }, { "name":"R0135_05625 glutathione S-transferase family protein\tK00799 GST; glutathione S-transferase [EC:2.5.1.18]" }, { "name":"R0135_05650 glutathione S-transferase\tK00799 GST; glutathione S-transferase [EC:2.5.1.18]" }, { "name":"R0135_09785 glutathione S-transferase family protein\tK00799 GST; glutathione S-transferase [EC:2.5.1.18]" }, { "name":"R0135_10085 glutathione S-transferase family protein\tK00799 GST; glutathione S-transferase [EC:2.5.1.18]" }, { "name":"R0135_13800 glutathione S-transferase family protein\tK00799 GST; glutathione S-transferase [EC:2.5.1.18]" }, { "name":"R0135_13890 glutathione S-transferase family protein\tK00799 GST; glutathione S-transferase [EC:2.5.1.18]" }, { "name":"R0135_14040 MAPEG family protein\tK00799 GST; glutathione S-transferase [EC:2.5.1.18]" }, { "name":"R0135_07300 glutathione S-transferase N-terminal domain-containing protein\tK03599 sspA; stringent starvation protein A" }, { "name":"R0135_00370 VWA domain-containing protein\tK07114 yfbK; Ca-activated chloride channel homolog" }, { "name":"R0135_00375 VWA domain-containing protein\tK07114 yfbK; Ca-activated chloride channel homolog" }, { "name":"R0135_04215 VWA domain-containing protein\tK07114 yfbK; Ca-activated chloride channel homolog" }, { "name":"R0135_04220 VWA domain-containing protein\tK07114 yfbK; Ca-activated chloride channel homolog" }, { "name":"R0135_03200 Bax inhibitor-1\/YccA family protein\tK19416 yccA; modulator of FtsH protease" }, { "name":"R0135_13590 mscL; (GenBank) large conductance mechanosensitive channel protein MscL\tK03282 mscL; large conductance mechanosensitive channel" }, { "name":"R0135_05315 mechanosensitive ion channel\tK22051 mscM; miniconductance mechanosensitive channel" }, { "name":"R0135_17500 mechanosensitive ion channel\tK03442 mscS; small conductance mechanosensitive channel" }, { "name":"R0135_03510 mechanosensitive ion channel family protein\tK16052 ynaI; MscS family membrane protein" }, { "name":"R0135_12590 mechanosensitive ion channel\tK16052 ynaI; MscS family membrane protein" }, { "name":"R0135_07425 mgtE; (GenBank) magnesium transporter\tK06213 mgtE; magnesium transporter" }, { "name":"R0135_16275 flagellar motor protein\tK02556 motA; chemotaxis protein MotA" }, { "name":"R0135_16300 pomA; (GenBank) flagellar motor protein PomA\tK02556 motA; chemotaxis protein MotA" }, { "name":"R0135_16280 OmpA family protein\tK02557 motB; chemotaxis protein MotB" }, { "name":"R0135_16295 flagellar motor protein MotB\tK02557 motB; chemotaxis protein MotB" }, { "name":"R0135_03420 MotA\/TolQ\/ExbB proton channel family protein\tK03561 exbB; biopolymer transport protein ExbB" }, { "name":"R0135_11130 MotA\/TolQ\/ExbB proton channel family protein\tK03561 exbB; biopolymer transport protein ExbB" }, { "name":"R0135_11135 MotA\/TolQ\/ExbB proton channel family protein\tK03561 exbB; biopolymer transport protein ExbB" }, { "name":"R0135_15125 MotA\/TolQ\/ExbB proton channel family protein\tK03561 exbB; biopolymer transport protein ExbB" }, { "name":"R0135_15130 MotA\/TolQ\/ExbB proton channel family protein\tK03561 exbB; biopolymer transport protein ExbB" }, { "name":"R0135_03415 biopolymer transporter ExbD\tK03559 exbD; biopolymer transport protein ExbD" }, { "name":"R0135_11120 biopolymer transporter ExbD\tK03559 exbD; biopolymer transport protein ExbD" }, { "name":"R0135_11125 biopolymer transporter ExbD\tK03559 exbD; biopolymer transport protein ExbD" }, { "name":"R0135_15120 biopolymer transporter ExbD\tK03559 exbD; biopolymer transport protein ExbD" }, { "name":"R0135_09200 tolQ; (GenBank) protein TolQ\tK03562 tolQ; biopolymer transport protein TolQ" }, { "name":"R0135_09195 tolR; (GenBank) protein TolR\tK03560 tolR; biopolymer transport protein TolR" }, { "name":"R0135_02840 magnesium transporter CorA family protein\tK03284 corA; magnesium transporter" }, { "name":"R0135_02800 zinc transporter ZntB\tK16074 zntB; zinc transporter" }, { "name":"R0135_02675 crcB; (GenBank) fluoride efflux transporter CrcB\tK06199 crcB; fluoride exporter" }, { "name":"R0135_00725 HlyC\/CorC family transporter\tK03699 tlyC; magnesium and cobalt exporter, CNNM family" }, { "name":"R0135_08820 OmpA family protein\tK03286 TC.OOP; OmpA-OmpF porin, OOP family" }, { "name":"R0135_12940 outer membrane protein transport protein\tK06076 fadL; long-chain fatty acid transport protein" }, { "name":"R0135_09710 TonB-dependent receptor\tK16091 fecA; Fe(3+) dicitrate transport protein" }, { "name":"R0135_01355 TonB-dependent receptor\tK16092 btuB; vitamin B12 transporter" }, { "name":"R0135_00155 TonB-dependent receptor\tK02014 TC.FEV.OM; iron complex outermembrane recepter protein" }, { "name":"R0135_00395 TonB-dependent receptor\tK02014 TC.FEV.OM; iron complex outermembrane recepter protein" }, { "name":"R0135_01885 TonB-dependent receptor\tK02014 TC.FEV.OM; iron complex outermembrane recepter protein" }, { "name":"R0135_03310 TonB-dependent receptor\tK02014 TC.FEV.OM; iron complex outermembrane recepter protein" }, { "name":"R0135_05280 TonB-dependent receptor\tK02014 TC.FEV.OM; iron complex outermembrane recepter protein" }, { "name":"R0135_05875 TonB-dependent receptor\tK02014 TC.FEV.OM; iron complex outermembrane recepter protein" }, { "name":"R0135_06195 TonB-dependent receptor\tK02014 TC.FEV.OM; iron complex outermembrane recepter protein" }, { "name":"R0135_06710 TonB-dependent receptor\tK02014 TC.FEV.OM; iron complex outermembrane recepter protein" }, { "name":"R0135_08185 TonB-dependent receptor\tK02014 TC.FEV.OM; iron complex outermembrane recepter protein" }, { "name":"R0135_08300 TonB-dependent receptor\tK02014 TC.FEV.OM; iron complex outermembrane recepter protein" }, { "name":"R0135_08890 TonB-dependent receptor\tK02014 TC.FEV.OM; iron complex outermembrane recepter protein" }, { "name":"R0135_09075 TonB-dependent receptor\tK02014 TC.FEV.OM; iron complex outermembrane recepter protein" }, { "name":"R0135_09130 TonB-dependent receptor\tK02014 TC.FEV.OM; iron complex outermembrane recepter protein" }, { "name":"R0135_09415 TonB-dependent receptor\tK02014 TC.FEV.OM; iron complex outermembrane recepter protein" }, { "name":"R0135_10400 TonB-dependent receptor\tK02014 TC.FEV.OM; iron complex outermembrane recepter protein" }, { "name":"R0135_11010 TonB-dependent receptor\tK02014 TC.FEV.OM; iron complex outermembrane recepter protein" }, { "name":"R0135_16400 TonB-dependent receptor\tK02014 TC.FEV.OM; iron complex outermembrane recepter protein" }, { "name":"R0135_06410 TolC family protein\tK07796 cusC; outer membrane protein, copper\/silver efflux system" }, { "name":"R0135_12155 TolC family outer membrane protein\tK12340 tolC; outer membrane protein" }, { "name":"R0135_07580 TolC family outer membrane protein\tK12543 lapE; outer membrane protein, adhesin transport system" }, { "name":"R0135_16340 efflux transporter outer membrane subunit\tK18904 nodT; outer membrane protein, multidrug efflux system" }, { "name":"R0135_03750 polysaccharide biosynthesis\/export family protein\tK20988 vpsN; polysaccharide biosynthesis\/export protein VpsN" }, { "name":"R0135_07800 polysaccharide export protein\tK01991 wza; polysaccharide biosynthesis\/export protein" }, { "name":"R0135_10235 SLBB domain-containing protein\tK01991 wza; polysaccharide biosynthesis\/export protein" }, { "name":"R0135_00065 bamA; (GenBank) outer membrane protein assembly factor BamA\tK07277 SAM50; outer membrane protein insertion porin family" }, { "name":"R0135_00995 bamB; (GenBank) outer membrane protein assembly factor BamB\tK17713 bamB; outer membrane protein assembly factor BamB" }, { "name":"R0135_17535 bamC; (GenBank) outer membrane protein assembly factor BamC\tK07287 bamC; outer membrane protein assembly factor BamC" }, { "name":"R0135_17040 outer membrane protein assembly factor BamD\tK05807 bamD; outer membrane protein assembly factor BamD" }, { "name":"R0135_16605 bamE; (GenBank) outer membrane protein assembly factor BamE\tK06186 bamE; outer membrane protein assembly factor BamE" }, { "name":"R0135_03955 BamA\/TamA family outer membrane protein\tK07278 tamA; translocation and assembly module TamA" }, { "name":"R0135_07390 lptA; (GenBank) lipopolysaccharide transport periplasmic protein LptA\tK09774 lptA; lipopolysaccharide export system protein LptA" }, { "name":"R0135_07385 lptC; (GenBank) LPS export ABC transporter periplasmic protein LptC\tK11719 lptC; lipopolysaccharide export system protein LptC" }, { "name":"R0135_14500 lptD; (GenBank) LPS assembly protein LptD\tK04744 lptD; LPS-assembly protein" }, { "name":"R0135_08405 lptE; (GenBank) LPS assembly lipoprotein LptE\tK03643 lptE; LPS-assembly lipoprotein" }, { "name":"R0135_03680 outer membrane beta-barrel protein\tK20920 vpsM; polysaccharide biosynthesis protein VpsM" }, { "name":"R0135_04270 MipA\/OmpV family protein\tK07274 mipA; MipA family protein" }, { "name":"R0135_08390 transporter associated domain-containing protein\tK06189 corC; hemolysin (HlyC) family protein" }, { "name":"R0135_10770 APC family permease\tK20265 gadC; glutamate:GABA antiporter" }, { "name":"R0135_06715 cation diffusion facilitator family transporter\tK13283 fieF; ferrous-iron efflux pump FieF" }, { "name":"R0135_06420 CusA\/CzcA family heavy metal efflux RND transporter\tK07787 cusA; copper\/silver efflux system protein" }, { "name":"R0135_01525 efflux RND transporter permease subunit\tK18138 acrB; multidrug efflux pump" }, { "name":"R0135_05675 efflux RND transporter permease subunit\tK18138 acrB; multidrug efflux pump" }, { "name":"R0135_09040 efflux RND transporter permease subunit\tK18138 acrB; multidrug efflux pump" }, { "name":"R0135_09570 efflux RND transporter permease subunit\tK18138 acrB; multidrug efflux pump" }, { "name":"R0135_12685 efflux RND transporter permease subunit\tK18138 acrB; multidrug efflux pump" }, { "name":"R0135_05560 efflux RND transporter permease subunit\tK18989 vexF; multidrug efflux pump" }, { "name":"R0135_12580 BCCT family transporter\tK02168 betT; choline\/glycine\/proline betaine transport protein" }, { "name":"R0135_07370 calcium\/sodium antiporter\tK07301 yrbG; cation:H+ antiporter" }, { "name":"R0135_08970 sodium:solute symporter family protein\tK14392 panF; sodium\/pantothenate symporter" }, { "name":"R0135_11015 sodium:solute symporter family protein\tK14392 panF; sodium\/pantothenate symporter" }, { "name":"R0135_01430 sodium:solute symporter family protein\tK14393 actP; cation\/acetate symporter" }, { "name":"R0135_01330 sstT; (GenBank) serine\/threonine transporter SstT\tK07862 sstT; serine\/threonine transporter" }, { "name":"R0135_13705 nhaA; (GenBank) Na+\/H+ antiporter NhaA\tK03313 nhaA; Na+:H+ antiporter, NhaA family" }, { "name":"R0135_02920 nhaB; (GenBank) sodium\/proton antiporter NhaB\tK03314 nhaB; Na+:H+ antiporter, NhaB family" }, { "name":"R0135_12510 nhaC; (GenBank) Na+\/H+ antiporter NhaC\tK03315 nhaC; Na+:H+ antiporter, NhaC family" }, { "name":"R0135_03165 Na+\/H+ antiporter NhaC family protein\tK18218 tet35; tetracycline resistance efflux pump" }, { "name":"R0135_09980 sodium:proton antiporter\tK03316 nhaP; Na+:H+ antiporter" }, { "name":"R0135_01390 cation:proton antiporter\tK26730 napA; Na+:H+ antiporter" }, { "name":"R0135_11885 TrkH family potassium uptake protein\tK03498 trkH; trk\/ktr system potassium uptake protein" }, { "name":"R0135_11890 trkA; (GenBank) Trk system potassium transporter TrkA\tK03499 trkA; trk\/ktr system potassium uptake protein" }, { "name":"R0135_13445 cytosine permease\tK10974 codB; cytosine permease" }, { "name":"R0135_13175 nucleobase:cation symporter-2 family protein\tK24206 uacT; uric acid transporter" }, { "name":"R0135_00350 NCS2 family permease\tK06901 pbuG; adenine\/guanine\/hypoxanthine permease" }, { "name":"R0135_14660 chloride channel protein\tK03281 clcA; chloride channel protein, CIC family" }, { "name":"R0135_01385 SulP family inorganic anion transporter\tK03321 TC.SULP; sulfate permease, SulP family" }, { "name":"R0135_02900 sulP; (GenBank) sulfate permease\tK03321 TC.SULP; sulfate permease, SulP family" }, { "name":"R0135_12855 SulP family inorganic anion transporter\tK03321 TC.SULP; sulfate permease, SulP family" }, { "name":"R0135_10610 TRAP transporter substrate-binding protein\tK11688 dctP; TRAP-type transport system periplasmic protein" }, { "name":"R0135_11600 TRAP transporter substrate-binding protein\tK11688 dctP; TRAP-type transport system periplasmic protein" }, { "name":"R0135_10605 TRAP transporter small permease\tK11689 dctQ; TRAP-type transport system small permease protein" }, { "name":"R0135_11585 TRAP transporter small permease subunit\tK11689 dctQ; TRAP-type transport system small permease protein" }, { "name":"R0135_10600 TRAP transporter large permease\tK11690 dctM; TRAP-type transport system large permease protein" }, { "name":"R0135_11590 TRAP transporter large permease subunit\tK11690 dctM; TRAP-type transport system large permease protein" }, { "name":"R0135_07975 Na\/Pi symporter\tK03324 yjbB; phosphate:Na+ symporter" }, { "name":"R0135_14445 MOP flippase family protein\tK16695 wzxC; lipopolysaccharide exporter" }, { "name":"R0135_16970 murJ; (GenBank) murein biosynthesis integral membrane protein MurJ\tK03980 murJ; putative peptidoglycan lipid II flippase" }, { "name":"R0135_02870 AEC family transporter\tK13936 mdcF; malonate transporter and related proteins" }, { "name":"R0135_08040 AEC family transporter\tK24180 mleP; malate permease and related proteins" }, { "name":"R0135_13960 LysE family translocator\tK05834 rhtB; homoserine\/homoserine lactone efflux protein" }, { "name":"R0135_04390 LysE family translocator\tK05835 rhtC; threonine efflux protein" }, { "name":"R0135_06360 LysE family translocator\tK05835 rhtC; threonine efflux protein" }, { "name":"R0135_16380 AzlC family ABC transporter permease\tK26605 azlC; branched chain amino acid efflux pump" }, { "name":"R0135_16385 AzlD domain-containing protein\tK26606 azlD; branched chain amino acid efflux pump" }, { "name":"R0135_16740 AI-2E family transporter\tK03548 perM; putative permease" }, { "name":"R0135_17455 queuosine precursor transporter\tK09125 yhhQ; queuosine precursor transporter" }, { "name":"R0135_07220 ftsW; (GenBank) putative lipid II flippase FtsW\tK03588 ftsW; peptidoglycan glycosyltransferase [EC:2.4.99.28]" }, { "name":"R0135_11115 energy transducer TonB\tK03832 tonB; periplasmic protein TonB" }, { "name":"R0135_11340 energy transducer TonB\tK03832 tonB; periplasmic protein TonB" }, { "name":"R0135_15115 TonB family protein\tK03832 tonB; periplasmic protein TonB" }, { "name":"R0135_09180 pal; (GenBank) peptidoglycan-associated lipoprotein Pal\tK03640 pal; peptidoglycan-associated lipoprotein" }, { "name":"R0135_09185 tolB; (GenBank) Tol-Pal system beta propeller repeat protein TolB\tK03641 tolB; TolB protein" }, { "name":"R0135_13185 sodium-translocating pyrophosphatase\tK15987 hppA; K(+)-stimulated pyrophosphate-energized sodium pump [EC:7.2.3.1]" }, { "name":"R0135_05415 sodium ion-translocating decarboxylase subunit beta\tK20509 madB; carboxybiotin decarboxylase [EC:7.2.4.1]" }, { "name":"R0135_05420 oadA; (GenBank) sodium-extruding oxaloacetate decarboxylase subunit alpha\tK01571 oadA; oxaloacetate decarboxylase (Na+ extruding) subunit alpha [EC:7.2.4.2]" }, { "name":"R0135_05425 OadG family protein\tK01573 oadG; oxaloacetate decarboxylase (Na+ extruding) subunit gamma" }, { "name":"R0135_06415 efflux RND transporter periplasmic adaptor subunit\tK07798 cusB; membrane fusion protein, copper\/silver efflux system" }, { "name":"R0135_07610 HlyD family type I secretion periplasmic adaptor subunit\tK12542 lapC; membrane fusion protein, adhesin transport system" }, { "name":"R0135_01530 efflux RND transporter periplasmic adaptor subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system" }, { "name":"R0135_05670 efflux RND transporter periplasmic adaptor subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system" }, { "name":"R0135_09045 efflux RND transporter periplasmic adaptor subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system" }, { "name":"R0135_09575 efflux RND transporter periplasmic adaptor subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system" }, { "name":"R0135_12680 efflux RND transporter periplasmic adaptor subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system" }, { "name":"R0135_05555 efflux RND transporter periplasmic adaptor subunit\tK18990 vexE; membrane fusion protein, multidrug efflux system" }, { "name":"R0135_03745 polysaccharide biosynthesis tyrosine autokinase\tK16554 exoP; polysaccharide biosynthesis transport protein [EC:2.7.10.3]" }, { "name":"R0135_07790 XrtA-associated tyrosine autokinase\tK00903 epsB; protein-tyrosine kinase [EC:2.7.10.3]" }, { "name":"R0135_07795 chain length-determining protein\tK25590 epsF; protein tyrosine kinase modulator" }, { "name":"R0135_07290 BON domain-containing protein\tK28369 dolP; outer membrane lipoprotein DolP" }, { "name":"R0135_07070 pnuC; (GenBank) nicotinamide riboside transporter PnuC\tK03811 pnuC; nicotinamide mononucleotide transporter" }, { "name":"R0135_05520 FeoA family protein\tK04758 feoA; ferrous iron transport protein A" }, { "name":"R0135_05515 ferrous iron transporter B\tK04759 feoB; ferrous iron transport protein B" }, { "name":"R0135_17505 PqiC family protein\tK09857 pqiC; intermembrane transport lipoprotein PqiC" }, { "name":"R0135_02150 heme lyase CcmF\/NrfE family subunit\tK02198 ccmF; cytochrome c-type biogenesis protein CcmF" }, { "name":"R0135_02725 uraH; (GenBank) hydroxyisourate hydrolase\tK07127 uraH; 5-hydroxyisourate hydrolase [EC:3.5.2.17]" } ] }, { "name":"02044 Secretion system [BR:cvb02044]", "children":[ { "name":"R0135_12155 TolC family outer membrane protein\tK12340 tolC; outer membrane protein" }, { "name":"R0135_07615 type I secretion system permease\/ATPase\tK12541 lapB; ATP-binding cassette, subfamily C, bacterial LapB" }, { "name":"R0135_07610 HlyD family type I secretion periplasmic adaptor subunit\tK12542 lapC; membrane fusion protein, adhesin transport system" }, { "name":"R0135_07580 TolC family outer membrane protein\tK12543 lapE; outer membrane protein, adhesin transport system" }, { "name":"R0135_01465 AAA family ATPase\tK02450 gspA; general secretion pathway protein A" }, { "name":"R0135_01470 general secretion pathway protein GspB\tK02451 gspB; general secretion pathway protein B" }, { "name":"R0135_07040 gspC; (GenBank) type II secretion system protein GspC\tK02452 gspC; general secretion pathway protein C" }, { "name":"R0135_07035 gspD; (GenBank) type II secretion system secretin GspD\tK02453 gspD; general secretion pathway protein D" }, { "name":"R0135_16845 gspD; (GenBank) type II secretion system secretin GspD\tK02453 gspD; general secretion pathway protein D" }, { "name":"R0135_07030 gspE; (GenBank) type II secretion system ATPase GspE\tK02454 gspE; general secretion pathway protein E [EC:7.4.2.8]" }, { "name":"R0135_12080 GspE\/PulE family protein\tK02454 gspE; general secretion pathway protein E [EC:7.4.2.8]" }, { "name":"R0135_16795 ATPase, T2SS\/T4P\/T4SS family\tK02454 gspE; general secretion pathway protein E [EC:7.4.2.8]" }, { "name":"R0135_07025 gspF; (GenBank) type II secretion system inner membrane protein GspF\tK02455 gspF; general secretion pathway protein F" }, { "name":"R0135_16800 type II secretion system F family protein\tK02455 gspF; general secretion pathway protein F" }, { "name":"R0135_04725 type II secretion system protein GspG\tK02456 gspG; general secretion pathway protein G" }, { "name":"R0135_07020 gspG; (GenBank) type II secretion system major pseudopilin GspG\tK02456 gspG; general secretion pathway protein G" }, { "name":"R0135_16805 gspG; (GenBank) type II secretion system major pseudopilin GspG\tK02456 gspG; general secretion pathway protein G" }, { "name":"R0135_07015 type II secretion system protein\tK02457 gspH; general secretion pathway protein H" }, { "name":"R0135_16810 prepilin-type N-terminal cleavage\/methylation domain-containing protein\tK02457 gspH; general secretion pathway protein H" }, { "name":"R0135_07010 gspI; (GenBank) type II secretion system minor pseudopilin GspI\tK02458 gspI; general secretion pathway protein I" }, { "name":"R0135_16815 prepilin-type N-terminal cleavage\/methylation domain-containing protein\tK02458 gspI; general secretion pathway protein I" }, { "name":"R0135_07005 gspJ; (GenBank) type II secretion system minor pseudopilin GspJ\tK02459 gspJ; general secretion pathway protein J" }, { "name":"R0135_16820 prepilin-type N-terminal cleavage\/methylation domain-containing protein\tK02459 gspJ; general secretion pathway protein J" }, { "name":"R0135_07000 gspK; (GenBank) type II secretion system minor pseudopilin GspK\tK02460 gspK; general secretion pathway protein K" }, { "name":"R0135_16825 hypothetical protein\tK02460 gspK; general secretion pathway protein K" }, { "name":"R0135_06995 gspL; (GenBank) type II secretion system protein GspL\tK02461 gspL; general secretion pathway protein L" }, { "name":"R0135_16830 PilN domain-containing protein\tK02461 gspL; general secretion pathway protein L" }, { "name":"R0135_06990 gspM; (GenBank) type II secretion system protein GspM\tK02462 gspM; general secretion pathway protein M" }, { "name":"R0135_16835 gspM; (GenBank) type II secretion system protein GspM\tK02462 gspM; general secretion pathway protein M" }, { "name":"R0135_06985 type II secretion system protein N\tK02463 gspN; general secretion pathway protein N" }, { "name":"R0135_07160 A24 family peptidase\tK02654 pilD; leader peptidase (prepilin peptidase) \/ N-methyltransferase [EC:3.4.23.43 2.1.1.-]" }, { "name":"R0135_07145 pilin\tK02650 pilA; type IV pilus assembly protein PilA" }, { "name":"R0135_14720 prepilin-type N-terminal cleavage\/methylation domain-containing protein\tK02650 pilA; type IV pilus assembly protein PilA" }, { "name":"R0135_07150 pilB; (GenBank) type IV-A pilus assembly ATPase PilB\tK02652 pilB; type IV pilus assembly protein PilB" }, { "name":"R0135_07155 type II secretion system F family protein\tK02653 pilC; type IV pilus assembly protein PilC" }, { "name":"R0135_17020 type IV pilin protein\tK02655 pilE; type IV pilus assembly protein PilE" }, { "name":"R0135_00975 pilW; (GenBank) type IV pilus biogenesis\/stability protein PilW\tK02656 pilF; type IV pilus assembly protein PilF" }, { "name":"R0135_12695 pilus assembly protein PilM\tK02662 pilM; type IV pilus assembly protein PilM" }, { "name":"R0135_12700 PilN domain-containing protein\tK02663 pilN; type IV pilus assembly protein PilN" }, { "name":"R0135_12705 pilO; (GenBank) type 4a pilus biogenesis protein PilO\tK02664 pilO; type IV pilus assembly protein PilO" }, { "name":"R0135_12710 pilus assembly protein PilP\tK02665 pilP; type IV pilus assembly protein PilP" }, { "name":"R0135_12715 pilQ; (GenBank) type IV pilus secretin PilQ\tK02666 pilQ; type IV pilus assembly protein PilQ" }, { "name":"R0135_11360 type IV pilus twitching motility protein PilT\tK02669 pilT; twitching motility protein PilT" }, { "name":"R0135_04130 PilT\/PilU family type 4a pilus ATPase\tK02670 pilU; twitching motility protein PilU" }, { "name":"R0135_11355 PilT\/PilU family type 4a pilus ATPase\tK02670 pilU; twitching motility protein PilU" }, { "name":"R0135_17000 pilV; (GenBank) type IV pilus modification protein PilV\tK02671 pilV; type IV pilus assembly protein PilV" }, { "name":"R0135_17005 PilW family protein\tK02672 pilW; type IV pilus assembly protein PilW" }, { "name":"R0135_17015 PilC\/PilY family type IV pilus protein\tK02674 pilY1; type IV pilus assembly protein PilY1" }, { "name":"R0135_03075 PilZ domain-containing protein\tK02676 pilZ; type IV pilus assembly protein PilZ" }, { "name":"R0135_03880 FimV\/HubP family polar landmark protein\tK08086 fimV; pilus assembly protein FimV" }, { "name":"R0135_11375 YggT family protein\tK02221 yggT; YggT family protein" }, { "name":"R0135_06760 ComEA family DNA-binding protein\tK02237 comEA; competence protein ComEA" }, { "name":"R0135_03425 DNA internalization-related competence protein ComEC\/Rec2\tK02238 comEC; competence protein ComEC" }, { "name":"R0135_16255 flhA; (GenBank) flagellar biosynthesis protein FlhA\tK02400 flhA; flagellar biosynthesis protein FlhA" }, { "name":"R0135_16250 flhB; (GenBank) flagellar biosynthesis protein FlhB\tK02401 flhB; flagellar biosynthesis protein FlhB" }, { "name":"R0135_16310 EscU\/YscU\/HrcU family type III secretion system export apparatus switch protein\tK04061 flhB2; flagellar biosynthesis protein" }, { "name":"R0135_16185 fliF; (GenBank) flagellar basal-body MS-ring\/collar protein FliF\tK02409 fliF; flagellar M-ring protein FliF" }, { "name":"R0135_16195 FliH\/SctL family protein\tK02411 fliH; flagellar assembly protein FliH" }, { "name":"R0135_16200 FliI\/YscN family ATPase\tK02412 fliI; flagellum-specific ATP synthase [EC:7.4.2.8]" }, { "name":"R0135_16225 fliN; (GenBank) flagellar motor switch protein FliN\tK02417 fliN; flagellar motor switch protein FliN" }, { "name":"R0135_16230 fliO; (GenBank) flagellar biosynthetic protein FliO\tK02418 fliO; flagellar protein FliO\/FliZ" }, { "name":"R0135_16235 fliP; (GenBank) flagellar type III secretion system pore protein FliP\tK02419 fliP; flagellar biosynthesis protein FliP" }, { "name":"R0135_16240 fliQ; (GenBank) flagellar biosynthesis protein FliQ\tK02420 fliQ; flagellar biosynthesis protein FliQ" }, { "name":"R0135_16245 fliR; (GenBank) flagellar biosynthetic protein FliR\tK02421 fliR; flagellar biosynthesis protein FliR" }, { "name":"R0135_00765 DsbC family protein\tK03981 dsbC; thiol:disulfide interchange protein DsbC [EC:5.3.4.1]" }, { "name":"R0135_07180 secA; (GenBank) preprotein translocase subunit SecA\tK03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]" }, { "name":"R0135_12410 secB; (GenBank) protein-export chaperone SecB\tK03071 secB; preprotein translocase subunit SecB" }, { "name":"R0135_00940 secD; (GenBank) protein translocase subunit SecD\tK03072 secD; preprotein translocase subunit SecD" }, { "name":"R0135_15650 secE; (GenBank) preprotein translocase subunit SecE\tK03073 secE; preprotein translocase subunit SecE" }, { "name":"R0135_00945 secF; (GenBank) protein translocase subunit SecF\tK03074 secF; preprotein translocase subunit SecF" }, { "name":"R0135_08710 secG; (GenBank) preprotein translocase subunit SecG\tK03075 secG; preprotein translocase subunit SecG" }, { "name":"R0135_15835 secY; (GenBank) preprotein translocase subunit SecY\tK03076 secY; preprotein translocase subunit SecY" }, { "name":"R0135_00735 ffh; (GenBank) signal recognition particle protein\tK03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]" }, { "name":"R0135_11430 ftsY; (GenBank) signal recognition particle-docking protein FtsY\tK03110 ftsY; fused signal recognition particle receptor" }, { "name":"R0135_02530 yajC; (GenBank) preprotein translocase subunit YajC\tK03210 yajC; preprotein translocase subunit YajC" }, { "name":"R0135_11725 yidC; (GenBank) membrane protein insertase YidC\tK03217 yidC; YidC\/Oxa1 family membrane protein insertase" }, { "name":"R0135_12605 tatA; (GenBank) twin-arginine translocase TatA\/TatE family subunit\tK03116 tatA; sec-independent protein translocase protein TatA" }, { "name":"R0135_12600 tatB; (GenBank) Sec-independent protein translocase protein TatB\tK03117 tatB; sec-independent protein translocase protein TatB" }, { "name":"R0135_12595 tatC; (GenBank) twin-arginine translocase subunit TatC\tK03118 tatC; sec-independent protein translocase protein TatC" } ] }, { "name":"02042 Bacterial toxins [BR:cvb02042]", "children":[ { "name":"R0135_00725 HlyC\/CorC family transporter\tK03699 tlyC; magnesium and cobalt exporter, CNNM family" } ] }, { "name":"02022 Two-component system [BR:cvb02022]", "children":[ { "name":"R0135_02195 phoR; (GenBank) phosphate regulon sensor histidine kinase PhoR\tK07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]" }, { "name":"R0135_02190 phoB; (GenBank) phosphate regulon transcriptional regulator PhoB\tK07657 phoB; two-component system, OmpR family, phosphate regulon response regulator PhoB" }, { "name":"R0135_13760 ATP-binding protein\tK07642 baeS; two-component system, OmpR family, sensor histidine kinase BaeS [EC:2.7.13.3]" }, { "name":"R0135_13755 response regulator\tK07664 baeR; two-component system, OmpR family, response regulator BaeR" }, { "name":"R0135_05175 LytTR family DNA-binding domain-containing protein\tK07705 lytT; two-component system, LytTR family, response regulator LytT" }, { "name":"R0135_12260 LytTR family DNA-binding domain-containing protein\tK07705 lytT; two-component system, LytTR family, response regulator LytT" }, { "name":"R0135_09660 sensor histidine kinase\tK08082 algZ; two-component system, LytTR family, sensor histidine kinase AlgZ [EC:2.7.13.3]" }, { "name":"R0135_09655 LytTR family DNA-binding domain-containing protein\tK08083 algR; two-component system, LytTR family, response regulator AlgR" }, { "name":"R0135_12425 glnL; (GenBank) nitrogen regulation protein NR(II)\tK07708 glnL; two-component system, NtrC family, nitrogen regulation sensor histidine kinase GlnL [EC:2.7.13.3]" }, { "name":"R0135_12420 ntrC; (GenBank) nitrogen regulation protein NR(I)\tK07712 glnG; two-component system, NtrC family, nitrogen regulation response regulator GlnG" }, { "name":"R0135_08625 sigma-54 dependent transcriptional regulator\tK07713 zraR; two-component system, NtrC family, response regulator HydG" }, { "name":"R0135_17030 HAMP domain-containing sensor histidine kinase\tK02668 pilS; two-component system, NtrC family, sensor histidine kinase PilS [EC:2.7.13.3]" }, { "name":"R0135_17025 sigma-54 dependent transcriptional regulator\tK02667 pilR; two-component system, NtrC family, response regulator PilR" }, { "name":"R0135_07830 prsR; (GenBank) PEP-CTERM-box response regulator transcription factor\tK02481 flgR; two-component system, NtrC family, response regulator" }, { "name":"R0135_00870 CheR family methyltransferase\tK13924 cheBR; two-component system, chemotaxis family, CheB\/CheR fusion protein [EC:2.1.1.80 3.1.1.61]" }, { "name":"R0135_15175 chemotaxis protein CheB\tK13924 cheBR; two-component system, chemotaxis family, CheB\/CheR fusion protein [EC:2.1.1.80 3.1.1.61]" }, { "name":"R0135_00865 response regulator\tK14987 fixJ; two-component system, LuxR family, response regulator FixJ" }, { "name":"R0135_16170 ATP-binding protein\tK10942 flrB; two-component system, sensor histidine kinase FlrB [EC:2.7.13.3]" }, { "name":"R0135_16175 sigma-54 dependent transcriptional regulator\tK10943 flrC; two-component system, response regulator FlrC" }, { "name":"R0135_00885 PAS domain-containing sensor histidine kinase\tK20975 K20975; two-component system, sensor histidine kinase [EC:2.7.13.3]" } ] }, { "name":"02035 Bacterial motility proteins [BR:cvb02035]", "children":[ { "name":"R0135_00870 CheR family methyltransferase\tK13924 cheBR; two-component system, chemotaxis family, CheB\/CheR fusion protein [EC:2.1.1.80 3.1.1.61]" }, { "name":"R0135_15175 chemotaxis protein CheB\tK13924 cheBR; two-component system, chemotaxis family, CheB\/CheR fusion protein [EC:2.1.1.80 3.1.1.61]" }, { "name":"R0135_16195 FliH\/SctL family protein\tK02411 fliH; flagellar assembly protein FliH" }, { "name":"R0135_16200 FliI\/YscN family ATPase\tK02412 fliI; flagellum-specific ATP synthase [EC:7.4.2.8]" }, { "name":"R0135_16205 fliJ; (GenBank) flagellar export protein FliJ\tK02413 fliJ; flagellar protein FliJ" }, { "name":"R0135_16230 fliO; (GenBank) flagellar biosynthetic protein FliO\tK02418 fliO; flagellar protein FliO\/FliZ" }, { "name":"R0135_16235 fliP; (GenBank) flagellar type III secretion system pore protein FliP\tK02419 fliP; flagellar biosynthesis protein FliP" }, { "name":"R0135_16240 fliQ; (GenBank) flagellar biosynthesis protein FliQ\tK02420 fliQ; flagellar biosynthesis protein FliQ" }, { "name":"R0135_16245 fliR; (GenBank) flagellar biosynthetic protein FliR\tK02421 fliR; flagellar biosynthesis protein FliR" }, { "name":"R0135_16255 flhA; (GenBank) flagellar biosynthesis protein FlhA\tK02400 flhA; flagellar biosynthesis protein FlhA" }, { "name":"R0135_16250 flhB; (GenBank) flagellar biosynthesis protein FlhB\tK02401 flhB; flagellar biosynthesis protein FlhB" }, { "name":"R0135_16190 fliG; (GenBank) flagellar motor switch protein FliG\tK02410 fliG; flagellar motor switch protein FliG" }, { "name":"R0135_16220 FliM\/FliN family flagellar motor switch protein\tK02416 fliM; flagellar motor switch protein FliM" }, { "name":"R0135_16225 fliN; (GenBank) flagellar motor switch protein FliN\tK02417 fliN; flagellar motor switch protein FliN" }, { "name":"R0135_16185 fliF; (GenBank) flagellar basal-body MS-ring\/collar protein FliF\tK02409 fliF; flagellar M-ring protein FliF" }, { "name":"R0135_16115 flagellar basal body P-ring protein FlgI\tK02394 flgI; flagellar P-ring protein FlgI" }, { "name":"R0135_16075 flgA; (GenBank) flagellar basal body P-ring formation chaperone FlgA\tK02386 flgA; flagellar basal body P-ring formation protein FlgA" }, { "name":"R0135_16110 flgH; (GenBank) flagellar basal body L-ring protein FlgH\tK02393 flgH; flagellar L-ring protein FlgH" }, { "name":"R0135_16215 flagellar basal body-associated FliL family protein\tK02415 fliL; flagellar protein FliL" }, { "name":"R0135_16180 fliE; (GenBank) flagellar hook-basal body complex protein FliE\tK02408 fliE; flagellar hook-basal body complex protein FliE" }, { "name":"R0135_16210 flagellar hook-length control protein FliK\tK02414 fliK; flagellar hook-length control protein FliK" }, { "name":"R0135_16080 flgB; (GenBank) flagellar basal body rod protein FlgB\tK02387 flgB; flagellar basal-body rod protein FlgB" }, { "name":"R0135_16085 flgC; (GenBank) flagellar basal body rod protein FlgC\tK02388 flgC; flagellar basal-body rod protein FlgC" }, { "name":"R0135_16090 flagellar hook capping FlgD N-terminal domain-containing protein\tK02389 flgD; flagellar basal-body rod modification protein FlgD" }, { "name":"R0135_16100 flagellar basal body rod protein FlgF\tK02391 flgF; flagellar basal-body rod protein FlgF" }, { "name":"R0135_16105 flgG; (GenBank) flagellar basal-body rod protein FlgG\tK02392 flgG; flagellar basal-body rod protein FlgG" }, { "name":"R0135_16120 flgJ; (GenBank) flagellar assembly peptidoglycan hydrolase FlgJ\tK02395 flgJ; peptidoglycan hydrolase FlgJ" }, { "name":"R0135_16095 flgE; (GenBank) flagellar hook protein FlgE\tK02390 flgE; flagellar hook protein FlgE" }, { "name":"R0135_16125 flgK; (GenBank) flagellar hook-associated protein FlgK\tK02396 flgK; flagellar hook-associated protein 1" }, { "name":"R0135_16130 flgL; (GenBank) flagellar hook-associated protein FlgL\tK02397 flgL; flagellar hook-associated protein 3 FlgL" }, { "name":"R0135_16065 flagellar protein FlgN\tK02399 flgN; flagellar biosynthesis protein FlgN" }, { "name":"R0135_16135 flagellin\tK02406 fliC; flagellin" }, { "name":"R0135_16145 fliD; (GenBank) flagellar filament capping protein FliD\tK02407 fliD; flagellar hook-associated protein 2" }, { "name":"R0135_16150 fliS; (GenBank) flagellar export chaperone FliS\tK02422 fliS; flagellar secretion chaperone FliS" }, { "name":"R0135_16270 RNA polymerase sigma factor FliA\tK02405 fliA; RNA polymerase sigma factor FliA" }, { "name":"R0135_16275 flagellar motor protein\tK02556 motA; chemotaxis protein MotA" }, { "name":"R0135_16300 pomA; (GenBank) flagellar motor protein PomA\tK02556 motA; chemotaxis protein MotA" }, { "name":"R0135_16280 OmpA family protein\tK02557 motB; chemotaxis protein MotB" }, { "name":"R0135_16295 flagellar motor protein MotB\tK02557 motB; chemotaxis protein MotB" }, { "name":"R0135_16170 ATP-binding protein\tK10942 flrB; two-component system, sensor histidine kinase FlrB [EC:2.7.13.3]" }, { "name":"R0135_16175 sigma-54 dependent transcriptional regulator\tK10943 flrC; two-component system, response regulator FlrC" }, { "name":"R0135_16070 flgM; (GenBank) flagellar biosynthesis anti-sigma factor FlgM\tK02398 flgM; negative regulator of flagellin synthesis FlgM" }, { "name":"R0135_16140 flagellar protein FlaG\tK06603 flaG; flagellar protein FlaG" }, { "name":"R0135_16260 flhF; (GenBank) flagellar biosynthesis protein FlhF\tK02404 flhF; flagellar biosynthesis protein FlhF" }, { "name":"R0135_16265 MinD\/ParA family protein\tK04562 flhG; flagellar biosynthesis protein FlhG" }, { "name":"R0135_17025 sigma-54 dependent transcriptional regulator\tK02667 pilR; two-component system, NtrC family, response regulator PilR" }, { "name":"R0135_17030 HAMP domain-containing sensor histidine kinase\tK02668 pilS; two-component system, NtrC family, sensor histidine kinase PilS [EC:2.7.13.3]" }, { "name":"R0135_11360 type IV pilus twitching motility protein PilT\tK02669 pilT; twitching motility protein PilT" }, { "name":"R0135_04130 PilT\/PilU family type 4a pilus ATPase\tK02670 pilU; twitching motility protein PilU" }, { "name":"R0135_11355 PilT\/PilU family type 4a pilus ATPase\tK02670 pilU; twitching motility protein PilU" }, { "name":"R0135_07145 pilin\tK02650 pilA; type IV pilus assembly protein PilA" }, { "name":"R0135_14720 prepilin-type N-terminal cleavage\/methylation domain-containing protein\tK02650 pilA; type IV pilus assembly protein PilA" }, { "name":"R0135_07150 pilB; (GenBank) type IV-A pilus assembly ATPase PilB\tK02652 pilB; type IV pilus assembly protein PilB" }, { "name":"R0135_07155 type II secretion system F family protein\tK02653 pilC; type IV pilus assembly protein PilC" }, { "name":"R0135_07160 A24 family peptidase\tK02654 pilD; leader peptidase (prepilin peptidase) \/ N-methyltransferase [EC:3.4.23.43 2.1.1.-]" }, { "name":"R0135_00975 pilW; (GenBank) type IV pilus biogenesis\/stability protein PilW\tK02656 pilF; type IV pilus assembly protein PilF" }, { "name":"R0135_12715 pilQ; (GenBank) type IV pilus secretin PilQ\tK02666 pilQ; type IV pilus assembly protein PilQ" }, { "name":"R0135_12710 pilus assembly protein PilP\tK02665 pilP; type IV pilus assembly protein PilP" }, { "name":"R0135_12705 pilO; (GenBank) type 4a pilus biogenesis protein PilO\tK02664 pilO; type IV pilus assembly protein PilO" }, { "name":"R0135_12700 PilN domain-containing protein\tK02663 pilN; type IV pilus assembly protein PilN" }, { "name":"R0135_12695 pilus assembly protein PilM\tK02662 pilM; type IV pilus assembly protein PilM" }, { "name":"R0135_03075 PilZ domain-containing protein\tK02676 pilZ; type IV pilus assembly protein PilZ" }, { "name":"R0135_17000 pilV; (GenBank) type IV pilus modification protein PilV\tK02671 pilV; type IV pilus assembly protein PilV" }, { "name":"R0135_17005 PilW family protein\tK02672 pilW; type IV pilus assembly protein PilW" }, { "name":"R0135_17015 PilC\/PilY family type IV pilus protein\tK02674 pilY1; type IV pilus assembly protein PilY1" }, { "name":"R0135_17020 type IV pilin protein\tK02655 pilE; type IV pilus assembly protein PilE" } ] }, { "name":"03037 Cilium and associated proteins" }, { "name":"04812 Cytoskeleton proteins [BR:cvb04812]", "children":[ { "name":"R0135_07460 rod shape-determining protein\tK03569 mreB; rod shape-determining protein MreB and related proteins" }, { "name":"R0135_07190 ftsZ; (GenBank) cell division protein FtsZ\tK03531 ftsZ; cell division protein FtsZ" }, { "name":"R0135_07195 ftsA; (GenBank) cell division protein FtsA\tK03590 ftsA; cell division protein FtsA" }, { "name":"R0135_11705 ParA family protein\tK03496 parA; chromosome partitioning protein" }, { "name":"R0135_14895 ParA family protein\tK03496 parA; chromosome partitioning protein" }, { "name":"R0135_11700 ParB\/RepB\/Spo0J family partition protein\tK03497 parB; ParB family transcriptional regulator, chromosome partitioning protein" } ] }, { "name":"04147 Exosome [BR:cvb04147]", "children":[ { "name":"R0135_02285 htpG; (GenBank) molecular chaperone HtpG\tK04079 HSP90A; molecular chaperone HtpG" }, { "name":"R0135_00840 class I fructose-bisphosphate aldolase\tK01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]" }, { "name":"R0135_05390 eno; (GenBank) phosphopyruvate hydratase\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]" }, { "name":"R0135_03490 glyceraldehyde-3-phosphate dehydrogenase\tK00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]" }, { "name":"R0135_05170 gap; (GenBank) type I glyceraldehyde-3-phosphate dehydrogenase\tK00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]" }, { "name":"R0135_05470 gap; (GenBank) type I glyceraldehyde-3-phosphate dehydrogenase\tK00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]" }, { "name":"R0135_05475 glyceraldehyde 3-phosphate dehydrogenase NAD-binding domain-containing protein\tK00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]" }, { "name":"R0135_11295 phosphoglycerate kinase\tK00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]" }, { "name":"R0135_11045 pyk; (GenBank) pyruvate kinase\tK00873 PK; pyruvate kinase [EC:2.7.1.40]" }, { "name":"R0135_06875 peptidylprolyl isomerase\tK03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8]" }, { "name":"R0135_04620 dipeptidase\tK01273 DPEP; membrane dipeptidase [EC:3.4.13.19]" }, { "name":"R0135_06690 membrane dipeptidase\tK01273 DPEP; membrane dipeptidase [EC:3.4.13.19]" }, { "name":"R0135_16930 groL; (GenBank) chaperonin GroEL\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]" }, { "name":"R0135_16630 dnaK; (GenBank) molecular chaperone DnaK\tK04043 dnaK; molecular chaperone DnaK" }, { "name":"R0135_04165 pgi; (GenBank) glucose-6-phosphate isomerase\tK01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]" }, { "name":"R0135_13630 prolyl oligopeptidase family serine peptidase\tK01278 DPP4; dipeptidyl-peptidase 4 [EC:3.4.14.5]" }, { "name":"R0135_13695 DPP IV N-terminal domain-containing protein\tK01278 DPP4; dipeptidyl-peptidase 4 [EC:3.4.14.5]" }, { "name":"R0135_00225 SMP-30\/gluconolactonase\/LRE family protein\tK01053 gnl; gluconolactonase [EC:3.1.1.17]" }, { "name":"R0135_00830 guaB; (GenBank) IMP dehydrogenase\tK00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]" }, { "name":"R0135_15640 tuf; (GenBank) elongation factor Tu\tK02358 tuf; elongation factor Tu" }, { "name":"R0135_15710 tuf; (GenBank) elongation factor Tu\tK02358 tuf; elongation factor Tu" }, { "name":"R0135_00195 histidine triad nucleotide-binding protein\tK02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]" }, { "name":"R0135_05490 AMP-binding protein\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]" }, { "name":"R0135_05640 AMP-binding protein\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]" }, { "name":"R0135_00330 acetyl-CoA C-acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" }, { "name":"R0135_03970 acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" }, { "name":"R0135_04435 acetyl-CoA C-acyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" }, { "name":"R0135_05075 acetyl-CoA C-acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" }, { "name":"R0135_11080 acetyl-CoA C-acyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" }, { "name":"R0135_11085 acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]" }, { "name":"R0135_11320 ahcY; (GenBank) adenosylhomocysteinase\tK01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1]" }, { "name":"R0135_01850 adk; (GenBank) adenylate kinase\tK00939 adk; adenylate kinase [EC:2.7.4.3]" }, { "name":"R0135_09665 argH; (GenBank) argininosuccinate lyase\tK01755 argH; argininosuccinate lyase [EC:4.3.2.1]" }, { "name":"R0135_08560 argininosuccinate synthase\tK01940 argG; argininosuccinate synthase [EC:6.3.4.5]" }, { "name":"R0135_05100 galK; (GenBank) galactokinase\tK00849 galK; galactokinase [EC:2.7.1.6]" }, { "name":"R0135_01950 glpK; (GenBank) glycerol kinase GlpK\tK00864 glpK; glycerol kinase [EC:2.7.1.30]" }, { "name":"R0135_08950 glutamine synthetase family protein\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]" }, { "name":"R0135_09260 glutamine synthetase family protein\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]" }, { "name":"R0135_10760 glutamine synthetase family protein\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]" }, { "name":"R0135_12435 glnA; (GenBank) glutamate--ammonia ligase\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]" }, { "name":"R0135_12885 glutamine synthetase family protein\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]" }, { "name":"R0135_14645 hemB; (GenBank) porphobilinogen synthase\tK01698 hemB; porphobilinogen synthase [EC:4.2.1.24]" }, { "name":"R0135_04800 hppD; (GenBank) 4-hydroxyphenylpyruvate dioxygenase\tK00457 HPD; 4-hydroxyphenylpyruvate dioxygenase [EC:1.13.11.27]" }, { "name":"R0135_10555 4a-hydroxytetrahydrobiopterin dehydratase\tK01724 PCBD; 4a-hydroxytetrahydrobiopterin dehydratase [EC:4.2.1.96]" }, { "name":"R0135_10725 alkaline phosphatase\tK01077 ALP; alkaline phosphatase [EC:3.1.3.1]" }, { "name":"R0135_11245 serA; (GenBank) phosphoglycerate dehydrogenase\tK00058 serA; D-3-phosphoglycerate dehydrogenase \/ 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]" }, { "name":"R0135_13440 phosphoglycerate dehydrogenase\tK00058 serA; D-3-phosphoglycerate dehydrogenase \/ 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]" }, { "name":"R0135_14560 purH; (GenBank) bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase\/IMP cyclohydrolase\tK00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase \/ IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]" }, { "name":"R0135_02270 lpdA; (GenBank) dihydrolipoyl dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]" }, { "name":"R0135_03015 FAD-binding protein\tK03522 fixB; electron transfer flavoprotein alpha subunit" }, { "name":"R0135_05140 zwf; (GenBank) glucose-6-phosphate dehydrogenase\tK00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363]" }, { "name":"R0135_08715 tpiA; (GenBank) triose-phosphate isomerase\tK01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]" }, { "name":"R0135_08445 lipocalin family protein\tK03098 APOD; apolipoprotein D and lipocalin family protein" } ] }, { "name":"02048 Prokaryotic defense system [BR:cvb02048]", "children":[ { "name":"R0135_00600 type I-E CRISPR-associated protein Cas6\/Cse3\/CasE\tK19126 casE; CRISPR system Cascade subunit CasE" }, { "name":"R0135_14175 DNA cytosine methyltransferase\tK00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]" }, { "name":"R0135_01985 pspB; (GenBank) envelope stress response membrane protein PspB\tK03970 pspB; phage shock protein B" }, { "name":"R0135_08155 HigA family addiction module antitoxin\tK21498 higA-1; antitoxin HigA-1" }, { "name":"R0135_07190 ftsZ; (GenBank) cell division protein FtsZ\tK03531 ftsZ; cell division protein FtsZ" }, { "name":"R0135_07460 rod shape-determining protein\tK03569 mreB; rod shape-determining protein MreB and related proteins" }, { "name":"R0135_12475 parC; (GenBank) DNA topoisomerase IV subunit A\tK02621 parC; topoisomerase IV subunit A [EC:5.6.2.2]" }, { "name":"R0135_12170 parE; (GenBank) DNA topoisomerase IV subunit B\tK02622 parE; topoisomerase IV subunit B [EC:5.6.2.2]" }, { "name":"R0135_04595 gltX; (GenBank) glutamate--tRNA ligase\tK01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]" }, { "name":"R0135_01760 succinate dehydrogenase assembly factor 2\tK09159 cptB; antitoxin CptB" }, { "name":"R0135_00960 IscS subfamily cysteine desulfurase\tK04487 iscS; cysteine desulfurase [EC:2.8.1.7]" } ] }, { "name":"04030 G protein-coupled receptors" }, { "name":"04050 Cytokine receptors" }, { "name":"04054 Pattern recognition receptors" }, { "name":"03310 Nuclear receptors" }, { "name":"04040 Ion channels" }, { "name":"04031 GTP-binding proteins" }, { "name":"04052 Cytokines and neuropeptides" }, { "name":"04515 Cell adhesion molecules" }, { "name":"04090 CD molecules [BR:cvb04090]", "children":[ { "name":"R0135_13630 prolyl oligopeptidase family serine peptidase\tK01278 DPP4; dipeptidyl-peptidase 4 [EC:3.4.14.5]" }, { "name":"R0135_13695 DPP IV N-terminal domain-containing protein\tK01278 DPP4; dipeptidyl-peptidase 4 [EC:3.4.14.5]" } ] }, { "name":"01504 Antimicrobial resistance genes [BR:cvb01504]", "children":[ { "name":"R0135_03165 Na+\/H+ antiporter NhaC family protein\tK18218 tet35; tetracycline resistance efflux pump" }, { "name":"R0135_01370 cytochrome C\tK18235 vgb; virginiamycin B lyase [EC:4.2.99.-]" }, { "name":"R0135_01530 efflux RND transporter periplasmic adaptor subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system" }, { "name":"R0135_05670 efflux RND transporter periplasmic adaptor subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system" }, { "name":"R0135_09045 efflux RND transporter periplasmic adaptor subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system" }, { "name":"R0135_09575 efflux RND transporter periplasmic adaptor subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system" }, { "name":"R0135_12680 efflux RND transporter periplasmic adaptor subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system" }, { "name":"R0135_01525 efflux RND transporter permease subunit\tK18138 acrB; multidrug efflux pump" }, { "name":"R0135_05675 efflux RND transporter permease subunit\tK18138 acrB; multidrug efflux pump" }, { "name":"R0135_09040 efflux RND transporter permease subunit\tK18138 acrB; multidrug efflux pump" }, { "name":"R0135_09570 efflux RND transporter permease subunit\tK18138 acrB; multidrug efflux pump" }, { "name":"R0135_12685 efflux RND transporter permease subunit\tK18138 acrB; multidrug efflux pump" }, { "name":"R0135_12155 TolC family outer membrane protein\tK12340 tolC; outer membrane protein" } ] }, { "name":"00535 Proteoglycans" }, { "name":"00536 Glycosaminoglycan binding proteins" }, { "name":"00537 Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:cvb00537]", "children":[ { "name":"R0135_10725 alkaline phosphatase\tK01077 ALP; alkaline phosphatase [EC:3.1.3.1]" }, { "name":"R0135_04620 dipeptidase\tK01273 DPEP; membrane dipeptidase [EC:3.4.13.19]" }, { "name":"R0135_06690 membrane dipeptidase\tK01273 DPEP; membrane dipeptidase [EC:3.4.13.19]" } ] }, { "name":"04091 Lectins" }, { "name":"04990 Domain-containing proteins not elsewhere classified" } ] }, { "name":"09185 Viral protein families", "children":[ { "name":"03200 Viral proteins" }, { "name":"03210 Viral fusion proteins" } ] }, { "name":"09184 RNA family", "children":[ { "name":"03100 Non-coding RNAs [BR:cvb03100]", "children":[ { "name":"R0135_04570 tRNA-Ala\tK14218 tRNA-Ala; tRNA Ala" }, { "name":"R0135_14700 tRNA-Ala\tK14218 tRNA-Ala; tRNA Ala" }, { "name":"R0135_17100 tRNA-Ala\tK14218 tRNA-Ala; tRNA Ala" }, { "name":"R0135_03625 tRNA-Arg\tK14219 tRNA-Arg; tRNA Arg" }, { "name":"R0135_04125 tRNA-Arg\tK14219 tRNA-Arg; tRNA Arg" }, { "name":"R0135_05965 tRNA-Arg\tK14219 tRNA-Arg; tRNA Arg" }, { "name":"R0135_13505 tRNA-Arg\tK14219 tRNA-Arg; tRNA Arg" }, { "name":"R0135_06110 tRNA-Asn\tK14220 tRNA-Asn; tRNA Asn" }, { "name":"R0135_04375 tRNA-Asp\tK14221 tRNA-Asp; tRNA Asp" }, { "name":"R0135_03380 tRNA-Cys\tK14222 tRNA-Cys; tRNA Cys" }, { "name":"R0135_07550 tRNA-Gln\tK14223 tRNA-Gln; tRNA Gln" }, { "name":"R0135_02350 tRNA-Glu\tK14224 tRNA-Glu; tRNA Glu" }, { "name":"R0135_02345 tRNA-Gly\tK14225 tRNA-Gly; tRNA Gly" }, { "name":"R0135_03385 tRNA-Gly\tK14225 tRNA-Gly; tRNA Gly" }, { "name":"R0135_13260 tRNA-Gly\tK14225 tRNA-Gly; tRNA Gly" }, { "name":"R0135_15630 tRNA-Gly\tK14225 tRNA-Gly; tRNA Gly" }, { "name":"R0135_03630 tRNA-His\tK14226 tRNA-His; tRNA His" }, { "name":"R0135_14695 tRNA-Ile\tK14227 tRNA-Ile; tRNA Ile" }, { "name":"R0135_17095 tRNA-Ile\tK14227 tRNA-Ile; tRNA Ile" }, { "name":"R0135_00695 tRNA-Leu\tK14228 tRNA-Leu; tRNA Leu" }, { "name":"R0135_03065 tRNA-Leu\tK14228 tRNA-Leu; tRNA Leu" }, { "name":"R0135_03240 tRNA-Leu\tK14228 tRNA-Leu; tRNA Leu" }, { "name":"R0135_08705 tRNA-Leu\tK14228 tRNA-Leu; tRNA Leu" }, { "name":"R0135_15355 tRNA-Leu\tK14228 tRNA-Leu; tRNA Leu" }, { "name":"R0135_09150 tRNA-Lys\tK14229 tRNA-Lys; tRNA Lys" }, { "name":"R0135_08235 tRNA-Met\tK14230 tRNA-Met; tRNA Met" }, { "name":"R0135_08700 tRNA-Met\tK14230 tRNA-Met; tRNA Met" }, { "name":"R0135_14300 tRNA-Ile\tK14230 tRNA-Met; tRNA Met" }, { "name":"R0135_12335 tRNA-Phe\tK14231 tRNA-Phe; tRNA Phe" }, { "name":"R0135_03635 tRNA-Pro\tK14232 tRNA-Pro; tRNA Pro" }, { "name":"R0135_06055 tRNA-Pro\tK14232 tRNA-Pro; tRNA Pro" }, { "name":"R0135_12800 tRNA-Pro\tK14232 tRNA-Pro; tRNA Pro" }, { "name":"R0135_00220 tRNA-Ser\tK14233 tRNA-Ser; tRNA Ser" }, { "name":"R0135_02385 tRNA-Ser\tK14233 tRNA-Ser; tRNA Ser" }, { "name":"R0135_03175 tRNA-Ser\tK14233 tRNA-Ser; tRNA Ser" }, { "name":"R0135_15615 tRNA-Thr\tK14234 tRNA-Thr; tRNA Thr" }, { "name":"R0135_15635 tRNA-Thr\tK14234 tRNA-Thr; tRNA Thr" }, { "name":"R0135_15645 tRNA-Trp\tK14235 tRNA-Trp; tRNA Trp" }, { "name":"R0135_15625 tRNA-Tyr\tK14236 tRNA-Tyr; tRNA Tyr" }, { "name":"R0135_04380 tRNA-Val\tK14237 tRNA-Val; tRNA Val" }, { "name":"R0135_10675 tRNA-Val\tK14237 tRNA-Val; tRNA Val" }, { "name":"R0135_14690 16S ribosomal RNA\tK01977 16SrRNA; 16S ribosomal RNA" }, { "name":"R0135_17090 16S ribosomal RNA\tK01977 16SrRNA; 16S ribosomal RNA" }, { "name":"R0135_14710 rrf; (GenBank) 5S ribosomal RNA\tK01985 5SrRNA; 5S ribosomal RNA" }, { "name":"R0135_17110 rrf; (GenBank) 5S ribosomal RNA\tK01985 5SrRNA; 5S ribosomal RNA" }, { "name":"R0135_07265 rnpB; (GenBank) RNase P RNA component class A\tK01978 rnpB; RNase P catalytic RNA component" }, { "name":"R0135_16545 ssrA; (GenBank) transfer-messenger RNA\tK15035 ssrA; transfer-messenger RNA" }, { "name":"R0135_11215 ssrS; (GenBank) 6S RNA\tK28358 ssrS; RNA polymerase binding 6S RNA" }, { "name":"R0135_03600 ffs; (GenBank) signal recognition particle sRNA small type\tK01983 ffs; signal recognition particle 4.5S RNA" } ] } ] } ] }, { "name":"09190 Not Included in Pathway or Brite", "children":[ { "name":"09191 Unclassified: metabolism", "children":[ { "name":"99980 Enzymes with EC numbers", "children":[ { "name":"R0135_08530 PQQ-dependent sugar dehydrogenase\tK21430 yliI; aldose sugar dehydrogenase [EC:1.1.5.-]" }, { "name":"R0135_10820 PQQ-dependent sugar dehydrogenase\tK21430 yliI; aldose sugar dehydrogenase [EC:1.1.5.-]" }, { "name":"R0135_13915 PQQ-dependent sugar dehydrogenase\tK21430 yliI; aldose sugar dehydrogenase [EC:1.1.5.-]" }, { "name":"R0135_06290 PQQ-dependent dehydrogenase, methanol\/ethanol family\tK17760 qheDH; quinohemoprotein ethanol dehydrogenase [EC:1.1.9.1]" }, { "name":"R0135_08215 PQQ-dependent dehydrogenase, methanol\/ethanol family\tK17760 qheDH; quinohemoprotein ethanol dehydrogenase [EC:1.1.9.1]" }, { "name":"R0135_08865 PQQ-dependent dehydrogenase, methanol\/ethanol family\tK17760 qheDH; quinohemoprotein ethanol dehydrogenase [EC:1.1.9.1]" }, { "name":"R0135_10535 PQQ-dependent dehydrogenase, methanol\/ethanol family\tK17760 qheDH; quinohemoprotein ethanol dehydrogenase [EC:1.1.9.1]" }, { "name":"R0135_13710 PQQ-dependent dehydrogenase, methanol\/ethanol family\tK17760 qheDH; quinohemoprotein ethanol dehydrogenase [EC:1.1.9.1]" }, { "name":"R0135_08225 coniferyl aldehyde dehydrogenase\tK00154 E1.2.1.68; coniferyl-aldehyde dehydrogenase [EC:1.2.1.68]" }, { "name":"R0135_11030 coniferyl aldehyde dehydrogenase\tK00154 E1.2.1.68; coniferyl-aldehyde dehydrogenase [EC:1.2.1.68]" }, { "name":"R0135_17445 indolepyruvate ferredoxin oxidoreductase family protein\tK04090 E1.2.7.8; indolepyruvate ferredoxin oxidoreductase [EC:1.2.7.8]" }, { "name":"R0135_05985 NADPH-dependent 2,4-dienoyl-CoA reductase\tK00219 fadH; 2,4-dienoyl-CoA reductase (NADPH2) [EC:1.3.1.34]" }, { "name":"R0135_16540 SagB family peptide dehydrogenase\tK05897 patGox; oxazoline\/thiazoline dehydrogenase [EC:1.3.3.16]" }, { "name":"R0135_10355 (2Fe-2S)-binding protein\tK07302 iorA; isoquinoline 1-oxidoreductase subunit alpha [EC:1.3.99.16]" }, { "name":"R0135_13210 (2Fe-2S)-binding protein\tK07302 iorA; isoquinoline 1-oxidoreductase subunit alpha [EC:1.3.99.16]" }, { "name":"R0135_13525 (2Fe-2S)-binding protein\tK07302 iorA; isoquinoline 1-oxidoreductase subunit alpha [EC:1.3.99.16]" }, { "name":"R0135_10350 molybdopterin cofactor-binding domain-containing protein\tK07303 iorB; isoquinoline 1-oxidoreductase subunit beta [EC:1.3.99.16]" }, { "name":"R0135_13215 molybdopterin cofactor-binding domain-containing protein\tK07303 iorB; isoquinoline 1-oxidoreductase subunit beta [EC:1.3.99.16]" }, { "name":"R0135_13530 molybdopterin cofactor-binding domain-containing protein\tK07303 iorB; isoquinoline 1-oxidoreductase subunit beta [EC:1.3.99.16]" }, { "name":"R0135_02850 solA; (GenBank) N-methyl-L-tryptophan oxidase\tK02846 solA; N-methyl-L-tryptophan oxidase [EC:1.5.3.-]" }, { "name":"R0135_03025 electron transfer flavoprotein-ubiquinone oxidoreductase\tK00311 ETFDH; electron-transferring-flavoprotein dehydrogenase [EC:1.5.5.1]" }, { "name":"R0135_08780 NADPH:quinone oxidoreductase family protein\tK00344 qor; NADPH:quinone reductase [EC:1.6.5.5]" }, { "name":"R0135_17470 quinone oxidoreductase\tK00344 qor; NADPH:quinone reductase [EC:1.6.5.5]" }, { "name":"R0135_08035 nitronate monooxygenase family protein\tK23948 E1.6.5.9; NADH:quinone reductase (non-electrogenic) [EC:1.6.5.9]" }, { "name":"R0135_01450 msrA; (GenBank) peptide-methionine (S)-S-oxide reductase MsrA\tK07304 msrA; peptide-methionine (S)-S-oxide reductase [EC:1.8.4.11]" }, { "name":"R0135_06920 msrA; (GenBank) peptide-methionine (S)-S-oxide reductase MsrA\tK07304 msrA; peptide-methionine (S)-S-oxide reductase [EC:1.8.4.11]" }, { "name":"R0135_14750 msrB; (GenBank) peptide-methionine (R)-S-oxide reductase MsrB\tK07305 msrB; peptide-methionine (R)-S-oxide reductase [EC:1.8.4.12]" }, { "name":"R0135_13200 yghU; (GenBank) glutathione-dependent disulfide-bond oxidoreductase\tK11209 yghU; GSH-dependent disulfide-bond oxidoreductase [EC:1.8.4.-]" }, { "name":"R0135_14770 glutathione S-transferase family protein\tK07393 ECM4; glutathionyl-hydroquinone reductase [EC:1.8.5.7]" }, { "name":"R0135_06140 cytochrome-c peroxidase\tK00428 E1.11.1.5; cytochrome c peroxidase [EC:1.11.1.5]" }, { "name":"R0135_09010 cytochrome c peroxidase\tK00428 E1.11.1.5; cytochrome c peroxidase [EC:1.11.1.5]" }, { "name":"R0135_02060 peroxiredoxin\tK03564 BCP; thioredoxin-dependent peroxiredoxin [EC:1.11.1.24]" }, { "name":"R0135_02520 bcp; (GenBank) thioredoxin-dependent thiol peroxidase\tK03564 BCP; thioredoxin-dependent peroxiredoxin [EC:1.11.1.24]" }, { "name":"R0135_08550 peroxiredoxin\tK24157 prxII; thioredoxin-dependent peroxiredoxin [EC:1.11.1.24]" }, { "name":"R0135_14780 pirin family protein\tK06911 PIR; quercetin 2,3-dioxygenase [EC:1.13.11.24]" }, { "name":"R0135_05890 TauD\/TfdA family dioxygenase\tK21728 sdpA; (S)-dichlorprop dioxygenase (2-oxoglutarate) [EC:1.14.11.43]" }, { "name":"R0135_11255 aspartyl\/asparaginyl beta-hydroxylase domain-containing protein\tK22616 olsC; ornithine lipid ester-linked acyl 2-hydroxylase [EC:1.14.11.58]" }, { "name":"R0135_16565 ferredoxin--NADP reductase\tK00528 fpr; ferredoxin\/flavodoxin---NADP+ reductase [EC:1.18.1.2 1.19.1.1]" }, { "name":"R0135_05130 ArsC\/Spx\/MgsR family protein\tK00537 arsC; arsenate reductase (glutaredoxin) [EC:1.20.4.1]" }, { "name":"R0135_10055 arsenate reductase ArsC\tK03741 arsC; arsenate reductase (thioredoxin) [EC:1.20.4.4]" }, { "name":"R0135_05370 protein-L-isoaspartate(D-aspartate) O-methyltransferase\tK00573 E2.1.1.77; protein-L-isoaspartate(D-aspartate) O-methyltransferase [EC:2.1.1.77]" }, { "name":"R0135_12520 cyclopropane-fatty-acyl-phospholipid synthase family protein\tK00574 cfa; cyclopropane-fatty-acyl-phospholipid synthase [EC:2.1.1.79]" }, { "name":"R0135_13010 tam; (GenBank) trans-aconitate 2-methyltransferase\tK00598 tam; trans-aconitate 2-methyltransferase [EC:2.1.1.144]" }, { "name":"R0135_12145 class I SAM-dependent methyltransferase\tK24288 meT1; MMP 1-O-methyltransferase [EC:2.1.1.365]" }, { "name":"R0135_02230 beta-ketoacyl-ACP synthase III\tK16872 E2.3.1.207; beta-ketodecanoyl-[acyl-carrier-protein] synthase [EC:2.3.1.207]" }, { "name":"R0135_08395 lnt; (GenBank) apolipoprotein N-acyltransferase\tK03820 lnt; apolipoprotein N-acyltransferase [EC:2.3.1.269]" }, { "name":"R0135_09125 3-keto-5-aminohexanoate cleavage protein\tK27838 E2.3.1.319; 3,5-dioxohexanoate:acetyl-CoA acetone transferase [EC:2.3.1.319]" }, { "name":"R0135_06520 N-acetyltransferase\tK03824 yhbS; putative acetyltransferase [EC:2.3.1.-]" }, { "name":"R0135_04905 GNAT family N-acetyltransferase\tK03829 yedL; putative acetyltransferase [EC:2.3.1.-]" }, { "name":"R0135_04695 glutaminyl-peptide cyclotransferase\tK22757 QCT; glutaminyl-peptide cyclotransferase [EC:2.3.2.5]" }, { "name":"R0135_02650 aat; (GenBank) leucyl\/phenylalanyl-tRNA--protein transferase\tK00684 aat; leucyl\/phenylalanyl-tRNA---protein transferase [EC:2.3.2.6]" }, { "name":"R0135_03815 DUF3488 and transglutaminase-like domain-containing protein\tK22452 tgpA; protein-glutamine gamma-glutamyltransferase [EC:2.3.2.13]" }, { "name":"R0135_02645 arginyltransferase\tK21420 bpt; leucyl-tRNA---protein transferase [EC:2.3.2.29]" }, { "name":"R0135_16775 sugar phosphorylase\tK22597 E2.4.1.352; glucosylglycerate phosphorylase [EC:2.4.1.352]" }, { "name":"R0135_11155 lgt; (GenBank) prolipoprotein diacylglyceryl transferase\tK13292 lgt; phosphatidylglycerol---prolipoprotein diacylglyceryl transferase [EC:2.5.1.145]" }, { "name":"R0135_03455 FAD:protein FMN transferase\tK03734 apbE; FAD:protein FMN transferase [EC:2.7.1.180]" }, { "name":"R0135_12085 glnE; (GenBank) bifunctional [glutamate--ammonia ligase]-adenylyl-L-tyrosine phosphorylase\/[glutamate--ammonia-ligase] adenylyltransferase\tK00982 glnE; [glutamine synthetase] adenylyltransferase \/ [glutamine synthetase]-adenylyl-L-tyrosine phosphorylase [EC:2.7.7.42 2.7.7.89]" }, { "name":"R0135_10315 YdiU family protein\tK08997 SELENOO; protein adenylyltransferase [EC:2.7.7.108]" }, { "name":"R0135_15620 sulfatase-like hydrolase\/transferase\tK01002 mdoB; phosphoglycerol transferase [EC:2.7.8.20]" }, { "name":"R0135_16665 aceK; (GenBank) bifunctional isocitrate dehydrogenase kinase\/phosphatase\tK00906 aceK; isocitrate dehydrogenase kinase\/phosphatase [EC:2.7.11.5 3.1.3.-]" }, { "name":"R0135_04925 carboxylesterase family protein\tK03929 pnbA; para-nitrobenzyl esterase [EC:3.1.1.-]" }, { "name":"R0135_12035 carboxylesterase family protein\tK03929 pnbA; para-nitrobenzyl esterase [EC:3.1.1.-]" }, { "name":"R0135_08770 thioesterase family protein\tK07107 ybgC; acyl-CoA thioester hydrolase [EC:3.1.2.-]" }, { "name":"R0135_12505 thioesterase family protein\tK07107 ybgC; acyl-CoA thioester hydrolase [EC:3.1.2.-]" }, { "name":"R0135_13005 thioesterase family protein\tK07107 ybgC; acyl-CoA thioester hydrolase [EC:3.1.2.-]" }, { "name":"R0135_10715 HAD-IB family hydrolase\tK15781 serB-plsC; putative phosphoserine phosphatase \/ 1-acylglycerol-3-phosphate O-acyltransferase [EC:3.1.3.3 2.3.1.51]" }, { "name":"R0135_03740 CpsB\/CapC family capsule biosynthesis tyrosine phosphatase\tK01104 E3.1.3.48; protein-tyrosine phosphatase [EC:3.1.3.48]" }, { "name":"R0135_09440 tyrosine-protein phosphatase\tK01104 E3.1.3.48; protein-tyrosine phosphatase [EC:3.1.3.48]" }, { "name":"R0135_14765 histidine phosphatase family protein\tK08296 sixA; phosphohistidine phosphatase [EC:3.1.3.-]" }, { "name":"R0135_13020 alkyl sulfatase dimerization domain-containing protein\tK25227 sdsA1; linear primary-alkylsulfatase [EC:3.1.6.21]" }, { "name":"R0135_01590 TatD family hydrolase\tK03424 tatD; TatD DNase family protein [EC:3.1.21.-]" }, { "name":"R0135_00685 thermonuclease family protein\tK01174 nuc; micrococcal nuclease [EC:3.1.31.1]" }, { "name":"R0135_04400 alpha\/beta fold hydrolase\tK01175 ybfF; esterase [EC:3.1.-.-]" }, { "name":"R0135_12140 prenyltransferase\tK27194 mmpH; MMP endo-(1,4)-3-O-methyl-alpha-D-mannosidase [EC:3.2.1.221]" }, { "name":"R0135_13835 family 16 glycosylhydrolase\tK16559 exoK; endo-1,3-1,4-beta-glycanase ExoK [EC:3.2.1.-]" }, { "name":"R0135_11905 def; (GenBank) peptide deformylase\tK01462 PDF; peptide deformylase [EC:3.5.1.88]" }, { "name":"R0135_13325 def; (GenBank) peptide deformylase\tK01462 PDF; peptide deformylase [EC:3.5.1.88]" }, { "name":"R0135_00515 acylase\tK07116 pvdQ; acyl-homoserine-lactone acylase [EC:3.5.1.97]" }, { "name":"R0135_05730 acylase\tK07116 pvdQ; acyl-homoserine-lactone acylase [EC:3.5.1.97]" }, { "name":"R0135_08025 acylase\tK07116 pvdQ; acyl-homoserine-lactone acylase [EC:3.5.1.97]" }, { "name":"R0135_15395 polysaccharide deacetylase\tK22278 pgdA; peptidoglycan-N-acetylglucosamine deacetylase [EC:3.5.1.104]" }, { "name":"R0135_02705 8-oxoguanine deaminase\tK18456 E3.5.4.32; 8-oxoguanine deaminase [EC:3.5.4.32]" }, { "name":"R0135_09155 Rid family hydrolase\tK09022 ridA; 2-iminobutanoate\/2-iminopropanoate deaminase [EC:3.5.99.10]" }, { "name":"R0135_03130 nucleoside triphosphate pyrophosphatase\tK25422 yceF; 7-methyl-GTP pyrophosphatase [EC:3.6.1.-]" }, { "name":"R0135_00390 MoxR family ATPase\tK03924 moxR; MoxR-like ATPase [EC:3.6.3.-]" }, { "name":"R0135_03825 AAA family ATPase\tK03924 moxR; MoxR-like ATPase [EC:3.6.3.-]" }, { "name":"R0135_04200 MoxR family ATPase\tK03924 moxR; MoxR-like ATPase [EC:3.6.3.-]" }, { "name":"R0135_07865 low molecular weight phosphotyrosine protein phosphatase\tK20201 ywlE; protein arginine phosphatase [EC:3.9.1.2]" }, { "name":"R0135_07855 FAD-binding oxidoreductase\tK27855 cndG; 1'-carboxy-chondrochloren decarboxylase [EC:4.1.1.129]" }, { "name":"R0135_14945 NAD(P)H-hydrate dehydratase\tK23997 nnr; ADP-dependent NAD(P)H-hydrate dehydratase \/ NAD(P)H-hydrate epimerase [EC:4.2.1.136 5.1.99.6]" }, { "name":"R0135_10575 alginate lyase family protein\tK20525 alg17C; oligo-alginate lyase [EC:4.2.2.26]" }, { "name":"R0135_16405 AMP-binding protein\tK02182 caiC; carnitine-CoA ligase [EC:6.2.1.48]" }, { "name":"R0135_01545 AMP-binding protein\tK25775 casG; steroid-24-oyl-CoA synthetase [EC:6.2.1.-]" }, { "name":"R0135_08805 class I adenylate-forming enzyme family protein\tK25775 casG; steroid-24-oyl-CoA synthetase [EC:6.2.1.-]" }, { "name":"R0135_16535 TOMM precursor leader peptide-binding protein\tK24411 patD; oxazoline\/thiazoline synthase [EC:6.2.2.2 6.2.2.3]" }, { "name":"R0135_00300 cphA; (GenBank) cyanophycin synthetase\tK03802 cphA; cyanophycin synthetase [EC:6.3.2.29 6.3.2.30]" }, { "name":"R0135_08585 mpl; (GenBank) UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase\tK02558 mpl; UDP-N-acetylmuramate: L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase [EC:6.3.2.45]" }, { "name":"R0135_17375 rsxD; (GenBank) electron transport complex subunit RsxD\tK03614 rnfD; H+\/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit D [EC:7.1.1.11 7.2.1.2]" }, { "name":"R0135_17380 rsxC; (GenBank) electron transport complex subunit RsxC\tK03615 rnfC; H+\/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit C [EC:7.1.1.11 7.2.1.2]" }, { "name":"R0135_17385 rsxB; (GenBank) electron transport complex subunit RsxB\tK03616 rnfB; H+\/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit B [EC:7.1.1.11 7.2.1.2]" }, { "name":"R0135_03485 Na(+)-translocating NADH-quinone reductase subunit A\tK00346 nqrA; Na+-transporting NADH:ubiquinone oxidoreductase subunit A [EC:7.2.1.1]" }, { "name":"R0135_03480 NADH:ubiquinone reductase (Na(+)-transporting) subunit B\tK00347 nqrB; Na+-transporting NADH:ubiquinone oxidoreductase subunit B [EC:7.2.1.1]" }, { "name":"R0135_03475 Na(+)-translocating NADH-quinone reductase subunit C\tK00348 nqrC; Na+-transporting NADH:ubiquinone oxidoreductase subunit C [EC:7.2.1.1]" }, { "name":"R0135_03470 NADH:ubiquinone reductase (Na(+)-transporting) subunit D\tK00349 nqrD; Na+-transporting NADH:ubiquinone oxidoreductase subunit D [EC:7.2.1.1]" }, { "name":"R0135_03465 nqrE; (GenBank) NADH:ubiquinone reductase (Na(+)-transporting) subunit E\tK00350 nqrE; Na+-transporting NADH:ubiquinone oxidoreductase subunit E [EC:7.2.1.1]" }, { "name":"R0135_03460 nqrF; (GenBank) NADH:ubiquinone reductase (Na(+)-transporting) subunit F\tK00351 nqrF; Na+-transporting NADH:ubiquinone oxidoreductase subunit F [EC:7.2.1.1]" }, { "name":"R0135_01695 heavy metal translocating P-type ATPase\tK01533 copB; P-type Cu2+ transporter [EC:7.2.2.9]" }, { "name":"R0135_00900 cation-transporting P-type ATPase\tK01537 ATP2C; P-type Ca2+ transporter type 2C [EC:7.2.2.10]" } ] }, { "name":"99981 Carbohydrate metabolism", "children":[ { "name":"R0135_17125 sfsA; (GenBank) DNA\/RNA nuclease SfsA\tK06206 sfsA; sugar fermentation stimulation protein A" }, { "name":"R0135_06915 CBS domain-containing protein\tK04767 acuB; acetoin utilization protein AcuB" }, { "name":"R0135_05450 (Fe-S)-binding protein\tK18928 lldE; L-lactate dehydrogenase complex protein LldE" }, { "name":"R0135_05455 lactate utilization protein B\tK18929 lldF; L-lactate dehydrogenase complex protein LldF" }, { "name":"R0135_05460 LUD domain-containing protein\tK00782 lldG; L-lactate dehydrogenase complex protein LldG" } ] }, { "name":"99982 Energy metabolism", "children":[ { "name":"R0135_05350 ferredoxin family protein\tK05524 fdxA; ferredoxin" }, { "name":"R0135_17370 rsxG; (GenBank) electron transport complex subunit RsxG\tK03612 rnfG; H+\/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit G" }, { "name":"R0135_17365 electron transport complex subunit E\tK03613 rnfE; H+\/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit E" }, { "name":"R0135_17390 rsxA; (GenBank) electron transport complex subunit RsxA\tK03617 rnfA; H+\/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit A" }, { "name":"R0135_03020 electron transfer flavoprotein subunit beta\/FixA family protein\tK03521 fixA; electron transfer flavoprotein beta subunit" } ] }, { "name":"99983 Lipid metabolism" }, { "name":"99984 Nucleotide metabolism" }, { "name":"99985 Amino acid metabolism", "children":[ { "name":"R0135_07490 cysZ; (GenBank) sulfate transporter CysZ\tK06203 cysZ; CysZ protein" }, { "name":"R0135_11365 YggS family pyridoxal phosphate-dependent enzyme\tK06997 yggS; PLP dependent protein" }, { "name":"R0135_08545 GNAT family protein\tK22479 argA; N-acetyltransferase" } ] }, { "name":"99986 Glycan metabolism", "children":[ { "name":"R0135_06770 lapB; (GenBank) lipopolysaccharide assembly protein LapB\tK19804 lapB; lipopolysaccharide assembly protein B" } ] }, { "name":"99987 Cofactor metabolism", "children":[ { "name":"R0135_09635 heme biosynthesis HemY N-terminal domain-containing protein\tK02498 hemY; HemY protein" }, { "name":"R0135_12620 ubiB; (GenBank) ubiquinone biosynthesis regulatory protein kinase UbiB\tK03688 ubiB; ubiquinone biosynthesis protein" }, { "name":"R0135_12625 SCP2 sterol-binding domain-containing protein\tK03690 ubiJ; ubiquinone biosynthesis accessory factor UbiJ" }, { "name":"R0135_09770 accessory factor UbiK family protein\tK09806 ubiK; ubiquinone biosynthesis accessory factor UbiK" }, { "name":"R0135_17155 alpha\/beta fold hydrolase\tK06049 bchO; magnesium chelatase accessory protein" } ] }, { "name":"99988 Secondary metabolism" }, { "name":"99999 Others", "children":[ { "name":"R0135_04520 DoxX family protein\tK15977 K15977; putative oxidoreductase" }, { "name":"R0135_13735 DoxX family protein\tK15977 K15977; putative oxidoreductase" }, { "name":"R0135_08145 carboxylesterase\tK06999 K06999; phospholipase\/carboxylesterase" } ] } ] }, { "name":"09192 Unclassified: genetic information processing", "children":[ { "name":"99973 Transcription", "children":[ { "name":"R0135_01315 cold-shock protein\tK03704 cspA; cold shock protein" }, { "name":"R0135_01605 cold shock domain-containing protein\tK03704 cspA; cold shock protein" }, { "name":"R0135_01610 cold shock domain-containing protein\tK03704 cspA; cold shock protein" }, { "name":"R0135_11065 cold-shock protein\tK03704 cspA; cold shock protein" }, { "name":"R0135_09705 P-II family nitrogen regulator\tK04752 glnK; nitrogen regulatory protein P-II 2" }, { "name":"R0135_09765 glnK; (GenBank) P-II family nitrogen regulator\tK04752 glnK; nitrogen regulatory protein P-II 2" }, { "name":"R0135_02865 Tex family protein\tK06959 tex; protein Tex" } ] }, { "name":"99974 Translation", "children":[ { "name":"R0135_06430 MBL fold metallo-hydrolase\tK07576 K07576; metallo-beta-lactamase family protein" } ] }, { "name":"99975 Protein processing", "children":[ { "name":"R0135_02630 clpS; (GenBank) ATP-dependent Clp protease adapter ClpS\tK06891 clpS; ATP-dependent Clp protease adaptor protein ClpS" }, { "name":"R0135_03060 tig; (GenBank) trigger factor\tK03545 tig; trigger factor" }, { "name":"R0135_02765 ureE; (GenBank) urease accessory protein UreE\tK03187 ureE; urease accessory protein" }, { "name":"R0135_02760 urease accessory protein UreF\tK03188 ureF; urease accessory protein" }, { "name":"R0135_02755 ureG; (GenBank) urease accessory protein UreG\tK03189 ureG; urease accessory protein" }, { "name":"R0135_02785 urease accessory protein UreD\tK03190 ureD; urease accessory protein" }, { "name":"R0135_16585 smpB; (GenBank) SsrA-binding protein SmpB\tK03664 smpB; SsrA-binding protein" }, { "name":"R0135_15305 HypC\/HybG\/HupF family hydrogenase formation chaperone\tK04653 hypC; hydrogenase expression\/formation protein HypC" }, { "name":"R0135_15300 hypD; (GenBank) hydrogenase formation protein HypD\tK04654 hypD; hydrogenase expression\/formation protein HypD" }, { "name":"R0135_15295 hypE; (GenBank) hydrogenase expression\/formation protein HypE\tK04655 hypE; hydrogenase expression\/formation protein HypE" }, { "name":"R0135_15310 hypF; (GenBank) carbamoyltransferase HypF\tK04656 hypF; hydrogenase maturation protein HypF" }, { "name":"R0135_09775 YifB family Mg chelatase-like AAA ATPase\tK07391 comM; magnesium chelatase family protein" }, { "name":"R0135_15040 proteasome-type protease\tK07395 K07395; putative proteasome-type protease" }, { "name":"R0135_14545 OsmC family protein\tK07397 yhfA; putative redox protein" }, { "name":"R0135_02975 nfuA; (GenBank) Fe-S biogenesis protein NfuA\tK07400 nfuA; Fe\/S biogenesis protein NfuA" }, { "name":"R0135_02740 xdhC; (GenBank) xanthine dehydrogenase accessory protein XdhC\tK07402 xdhC; xanthine dehydrogenase accessory factor" }, { "name":"R0135_03290 XdhC family protein\tK07402 xdhC; xanthine dehydrogenase accessory factor" } ] }, { "name":"99976 Replication and repair", "children":[ { "name":"R0135_16915 MGMT family protein\tK07443 ybaZ; methylated-DNA-protein-cysteine methyltransferase related protein" }, { "name":"R0135_11465 radC; (GenBank) DNA repair protein RadC\tK03630 radC; DNA repair protein RadC" }, { "name":"R0135_11825 rmuC; (GenBank) DNA recombination protein RmuC\tK09760 rmuC; DNA recombination protein RmuC" }, { "name":"R0135_07280 YraN family protein\tK07460 yraN; putative endonuclease" }, { "name":"R0135_09610 GIY-YIG nuclease family protein\tK07461 K07461; putative endonuclease" }, { "name":"R0135_11915 dprA; (GenBank) DNA-processing protein DprA\tK04096 smf; DNA processing protein" }, { "name":"R0135_02670 replication-associated recombination protein A\tK07478 ycaJ; putative ATPase" }, { "name":"R0135_01065 IS30 family transposase\tK07482 K07482; transposase, IS30 family" }, { "name":"R0135_01110 IS30 family transposase\tK07482 K07482; transposase, IS30 family" }, { "name":"R0135_01180 IS30 family transposase\tK07482 K07482; transposase, IS30 family" }, { "name":"R0135_01205 IS30 family transposase\tK07482 K07482; transposase, IS30 family" }, { "name":"R0135_03335 IS3 family transposase\tK07497 K07497; putative transposase" }, { "name":"R0135_14405 IS3 family transposase\tK07497 K07497; putative transposase" }, { "name":"R0135_08180 IS6 family transposase\tK07498 K07498; putative transposase" } ] }, { "name":"99979 Viral proteins" }, { "name":"99998 Others", "children":[ { "name":"R0135_01980 pspA; (GenBank) phage shock protein PspA\tK03969 pspA; phage shock protein A" }, { "name":"R0135_03590 YbaB\/EbfC family nucleoid-associated protein\tK09747 ebfC; nucleoid-associated protein EbfC" }, { "name":"R0135_16045 DASH family cryptochrome\tK25656 cry; cryptochrome" } ] } ] }, { "name":"09193 Unclassified: signaling and cellular processes", "children":[ { "name":"99977 Transport", "children":[ { "name":"R0135_05185 MFS transporter\tK03292 TC.GPH; glycoside\/pentoside\/hexuronide:cation symporter, GPH family" }, { "name":"R0135_10850 MFS transporter\tK03292 TC.GPH; glycoside\/pentoside\/hexuronide:cation symporter, GPH family" }, { "name":"R0135_11790 MFS transporter\tK03292 TC.GPH; glycoside\/pentoside\/hexuronide:cation symporter, GPH family" }, { "name":"R0135_04580 amino acid permease\tK03294 TC.APA; basic amino acid\/polyamine antiporter, APA family" }, { "name":"R0135_05435 peptide MFS transporter\tK03305 TC.POT; proton-dependent oligopeptide transporter, POT family" }, { "name":"R0135_12070 anion permease\tK03306 TC.PIT; inorganic phosphate transporter, PiT family" }, { "name":"R0135_05110 SLC5 family protein\tK03307 TC.SSS; solute:Na+ symporter, SSS family" }, { "name":"R0135_08020 solute:sodium symporter family transporter\tK03307 TC.SSS; solute:Na+ symporter, SSS family" }, { "name":"R0135_13655 putP; (GenBank) sodium\/proline symporter PutP\tK03307 TC.SSS; solute:Na+ symporter, SSS family" }, { "name":"R0135_03250 sodium-dependent transporter\tK03308 TC.NSS; neurotransmitter:Na+ symporter, NSS family" }, { "name":"R0135_06970 sodium-dependent transporter\tK03308 TC.NSS; neurotransmitter:Na+ symporter, NSS family" }, { "name":"R0135_16590 sodium-dependent transporter\tK03308 TC.NSS; neurotransmitter:Na+ symporter, NSS family" }, { "name":"R0135_02535 sodium:alanine symporter family protein\tK03310 TC.AGCS; alanine or glycine:cation symporter, AGCS family" }, { "name":"R0135_06965 alanine\/glycine:cation symporter family protein\tK03310 TC.AGCS; alanine or glycine:cation symporter, AGCS family" }, { "name":"R0135_07910 alanine\/glycine:cation symporter family protein\tK03310 TC.AGCS; alanine or glycine:cation symporter, AGCS family" }, { "name":"R0135_12050 alanine\/glycine:cation symporter family protein\tK03310 TC.AGCS; alanine or glycine:cation symporter, AGCS family" }, { "name":"R0135_05700 bile acid:sodium symporter\tK03453 TC.BASS; bile acid:Na+ symporter, BASS family" }, { "name":"R0135_01895 NupC\/NupG family nucleoside CNT transporter\tK03317 TC.CNT; concentrative nucleoside transporter, CNT family" } ] }, { "name":"99978 Cell growth", "children":[ { "name":"R0135_06860 inner membrane-spanning protein YciB\tK06190 ispZ; intracellular septation protein" }, { "name":"R0135_12390 peptidoglycan DD-metalloendopeptidase family protein\tK22719 envC; murein hydrolase activator" } ] }, { "name":"99993 Cell motility" }, { "name":"99995 Signaling proteins", "children":[ { "name":"R0135_07095 ampE; (GenBank) regulatory signaling modulator protein AmpE\tK03807 ampE; AmpE protein" }, { "name":"R0135_03545 universal stress protein\tK06149 uspA; universal stress protein A" }, { "name":"R0135_02015 universal stress protein\tK14055 uspE; universal stress protein E" }, { "name":"R0135_04780 universal stress protein\tK14055 uspE; universal stress protein E" }, { "name":"R0135_12440 typA; (GenBank) translational GTPase TypA\tK06207 typA; GTP-binding protein" }, { "name":"R0135_12540 ChrR family anti-sigma-E factor\tK07167 chrR; putative transcriptional regulator" }, { "name":"R0135_08380 PhoH family protein\tK06217 phoH; phosphate starvation-inducible protein PhoH and related proteins" }, { "name":"R0135_14920 PhoH family protein\tK07175 phoH2; PhoH-like ATPase" }, { "name":"R0135_01440 putative nucleotidyltransferase substrate binding domain-containing protein\tK07182 K07182; CBS domain-containing protein" }, { "name":"R0135_06870 TIGR04211 family SH3 domain-containing protein\tK07184 ygiM; SH3 domain protein" } ] }, { "name":"99992 Structural proteins", "children":[ { "name":"R0135_02665 outer-membrane lipoprotein carrier protein LolA\tK03634 lolA; outer membrane lipoprotein carrier protein" }, { "name":"R0135_07530 lolB; (GenBank) lipoprotein insertase outer membrane protein LolB\tK02494 lolB; outer membrane lipoprotein LolB" }, { "name":"R0135_04650 VacJ family lipoprotein\tK04754 mlaA; phospholipid-binding lipoprotein MlaA" }, { "name":"R0135_00070 OmpH family outer membrane protein\tK06142 hlpA; outer membrane protein" }, { "name":"R0135_05360 peptidoglycan DD-metalloendopeptidase family protein\tK06194 nlpD; lipoprotein NlpD" }, { "name":"R0135_01675 OmpW family outer membrane protein\tK07275 ompW; outer membrane protein" }, { "name":"R0135_10275 AsmA family protein\tK07289 asmA; AsmA protein" }, { "name":"R0135_16505 NHLP bacteriocin system secretion protein\tK02022 ABC.MR.TX; HlyD family secretion protein" }, { "name":"R0135_06315 efflux RND transporter periplasmic adaptor subunit\tK02005 ABC.CD.TX; HlyD family secretion protein" }, { "name":"R0135_02145 ccmE; (GenBank) cytochrome c maturation protein CcmE\tK02197 ccmE; cytochrome c-type biogenesis protein CcmE" }, { "name":"R0135_02160 cytochrome c-type biogenesis protein\tK02200 ccmH; cytochrome c-type biogenesis protein CcmH" }, { "name":"R0135_02165 ccmI; (GenBank) c-type cytochrome biogenesis protein CcmI\tK02200 ccmH; cytochrome c-type biogenesis protein CcmH" } ] }, { "name":"99994 Others", "children":[ { "name":"R0135_02220 phoU; (GenBank) phosphate signaling complex protein PhoU\tK02039 phoU; phosphate transport system protein" }, { "name":"R0135_09345 bacterioferritin-associated ferredoxin\tK02192 bfd; bacterioferritin-associated ferredoxin" }, { "name":"R0135_14375 apaG; (GenBank) Co2+\/Mg2+ efflux protein ApaG\tK06195 apaG; ApaG protein" } ] } ] }, { "name":"09194 Poorly characterized", "children":[ { "name":"99996 General function prediction only", "children":[ { "name":"R0135_03840 CvpA family protein\tK03558 cvpA; membrane protein required for colicin V production" }, { "name":"R0135_02395 glucosaminidase domain-containing protein\tK03796 bax; Bax protein" }, { "name":"R0135_12465 GNAT family N-acetyltransferase\tK02348 elaA; ElaA protein" }, { "name":"R0135_01005 group III truncated hemoglobin\tK06886 glbN; hemoglobin" }, { "name":"R0135_01535 DUF3336 domain-containing protein\tK07001 K07001; NTE family protein" }, { "name":"R0135_10475 patatin-like phospholipase family protein\tK07001 K07001; NTE family protein" }, { "name":"R0135_13030 patatin-like phospholipase family protein\tK07001 K07001; NTE family protein" }, { "name":"R0135_14670 erpA; (GenBank) iron-sulfur cluster insertion protein ErpA\tK15724 erpA; iron-sulfur cluster insertion protein" }, { "name":"R0135_10015 sufB; (GenBank) Fe-S cluster assembly protein SufB\tK09014 sufB; Fe-S cluster assembly protein SufB" }, { "name":"R0135_10005 sufD; (GenBank) Fe-S cluster assembly protein SufD\tK09015 sufD; Fe-S cluster assembly protein SufD" }, { "name":"R0135_03945 metal-dependent hydrolase\tK07038 K07038; inner membrane protein" }, { "name":"R0135_14075 YihY\/virulence factor BrkB family protein\tK07058 K07058; membrane protein" }, { "name":"R0135_17480 YihY family inner membrane protein\tK07058 K07058; membrane protein" }, { "name":"R0135_16920 FxsA family protein\tK07113 fxsA; UPF0716 protein FxsA" }, { "name":"R0135_09985 SufE family protein\tK02426 sufE; cysteine desulfuration protein SufE" }, { "name":"R0135_01655 rhodanese-related sulfurtransferase\tK07146 K07146; UPF0176 protein" }, { "name":"R0135_02610 hflD; (GenBank) high frequency lysogenization protein HflD\tK07153 hflD; high frequency lysogenization protein" }, { "name":"R0135_15015 LemA family protein\tK03744 lemA; LemA protein" }, { "name":"R0135_04030 SlyX family protein\tK03745 slyX; SlyX protein" }, { "name":"R0135_03845 SPOR domain-containing protein\tK03749 dedD; DedD protein" }, { "name":"R0135_05365 DUF368 domain-containing protein\tK08974 K08974; putative membrane protein" }, { "name":"R0135_13550 YchJ family metal-binding protein\tK09858 K09858; SEC-C motif domain protein" }, { "name":"R0135_10490 zinc ribbon domain-containing protein YjdM\tK06193 phnA; protein PhnA" } ] }, { "name":"99997 Function unknown", "children":[ { "name":"R0135_16375 alpha\/beta fold hydrolase\tK06889 K06889; uncharacterized protein" }, { "name":"R0135_13580 CoA-binding protein\tK06929 K06929; uncharacterized protein" }, { "name":"R0135_00720 DUF1289 domain-containing protein\tK06938 K06938; uncharacterized protein" }, { "name":"R0135_03665 DUF1289 domain-containing protein\tK06938 K06938; uncharacterized protein" }, { "name":"R0135_12530 FAD-dependent oxidoreductase\tK06954 K06954; uncharacterized protein" }, { "name":"R0135_10920 GNAT family N-acetyltransferase\tK06977 K06977; uncharacterized protein" }, { "name":"R0135_02820 succinylglutamate desuccinylase\/aspartoacylase family protein\tK06987 K06987; uncharacterized protein" }, { "name":"R0135_13500 M14 family metallopeptidase\tK06987 K06987; uncharacterized protein" }, { "name":"R0135_12055 VOC family protein\tK06991 K06991; uncharacterized protein" }, { "name":"R0135_04705 cysteine peptidase family C39 domain-containing protein\tK06992 K06992; uncharacterized protein" }, { "name":"R0135_08960 cupin domain-containing protein\tK06995 K06995; uncharacterized protein" }, { "name":"R0135_04070 VOC family protein\tK06996 K06996; uncharacterized protein" }, { "name":"R0135_07850 outer membrane lipoprotein-sorting protein\tK07003 K07003; uncharacterized protein" }, { "name":"R0135_08580 MMPL family transporter\tK07003 K07003; uncharacterized protein" }, { "name":"R0135_01275 pyridoxamine 5'-phosphate oxidase family protein\tK07006 K07006; uncharacterized protein" }, { "name":"R0135_08520 pyridoxamine 5'-phosphate oxidase family protein\tK07006 K07006; uncharacterized protein" }, { "name":"R0135_08910 metal-dependent hydrolase\tK07044 K07044; uncharacterized protein" }, { "name":"R0135_08485 neutral zinc metallopeptidase\tK07054 K07054; uncharacterized protein" }, { "name":"R0135_03275 TIGR01777 family oxidoreductase\tK07071 K07071; uncharacterized protein" }, { "name":"R0135_01905 sulfite exporter TauE\/SafE family protein\tK07090 K07090; uncharacterized protein" }, { "name":"R0135_04835 sulfite exporter TauE\/SafE family protein\tK07090 K07090; uncharacterized protein" }, { "name":"R0135_10880 sulfite exporter TauE\/SafE family protein\tK07090 K07090; uncharacterized protein" }, { "name":"R0135_16580 sulfite exporter TauE\/SafE family protein\tK07090 K07090; uncharacterized protein" }, { "name":"R0135_00345 phosphoribosyltransferase family protein\tK07101 K07101; uncharacterized protein" }, { "name":"R0135_13140 phosphoribosyltransferase family protein\tK07101 K07101; uncharacterized protein" }, { "name":"R0135_13170 phosphoribosyltransferase family protein\tK07101 K07101; uncharacterized protein" }, { "name":"R0135_05535 YeeE\/YedE thiosulfate transporter family protein\tK07112 K07112; uncharacterized protein" }, { "name":"R0135_05540 DUF6691 family protein\tK07112 K07112; uncharacterized protein" }, { "name":"R0135_12920 DUF6691 family protein\tK07112 K07112; uncharacterized protein" }, { "name":"R0135_12925 YeeE\/YedE thiosulfate transporter family protein\tK07112 K07112; uncharacterized protein" }, { "name":"R0135_07275 penicillin-binding protein activator\tK07121 K07121; uncharacterized protein" }, { "name":"R0135_02375 SDR family oxidoreductase\tK07124 K07124; uncharacterized protein" }, { "name":"R0135_17555 SDR family oxidoreductase\tK07124 K07124; uncharacterized protein" }, { "name":"R0135_13265 tetratricopeptide repeat protein\tK07126 K07126; uncharacterized protein" }, { "name":"R0135_06270 MOSC N-terminal beta barrel domain-containing protein\tK07140 K07140; MOSC domain-containing protein" }, { "name":"R0135_10865 MOSC domain-containing protein\tK07140 K07140; MOSC domain-containing protein" }, { "name":"R0135_08575 LON peptidase substrate-binding domain-containing protein\tK07157 K07157; uncharacterized protein" }, { "name":"R0135_09555 VWA domain-containing protein\tK07161 K07161; uncharacterized protein" }, { "name":"R0135_11730 yidD; (GenBank) membrane protein insertion efficiency factor YidD\tK08998 K08998; uncharacterized protein" }, { "name":"R0135_01360 DUF501 domain-containing protein\tK09009 K09009; uncharacterized protein" }, { "name":"R0135_14335 GatB\/YqeY domain-containing protein\tK09117 K09117; uncharacterized protein" }, { "name":"R0135_09295 DUF493 domain-containing protein\tK09158 K09158; uncharacterized protein" }, { "name":"R0135_01400 YcgN family cysteine cluster protein\tK09160 K09160; uncharacterized protein" }, { "name":"R0135_12525 DUF1365 domain-containing protein\tK09701 K09701; uncharacterized protein" }, { "name":"R0135_13455 DUF917 domain-containing protein\tK09703 K09703; uncharacterized protein" }, { "name":"R0135_00400 cupin domain-containing protein\tK09705 K09705; uncharacterized protein" }, { "name":"R0135_05485 YaiI\/YqxD family protein\tK09768 K09768; uncharacterized protein" }, { "name":"R0135_06865 YciI family protein\tK09780 K09780; uncharacterized protein" }, { "name":"R0135_02025 DUF808 domain-containing protein\tK09781 K09781; uncharacterized protein" }, { "name":"R0135_00190 Trm112 family protein\tK09791 K09791; uncharacterized protein" }, { "name":"R0135_01685 sulfite exporter TauE\/SafE family protein\tK09792 K09792; uncharacterized protein" }, { "name":"R0135_15720 DUF465 domain-containing protein\tK09794 K09794; uncharacterized protein" }, { "name":"R0135_13225 SIMPL domain-containing protein\tK09797 K09797; uncharacterized protein" }, { "name":"R0135_16600 RnfH family protein\tK09801 K09801; uncharacterized protein" }, { "name":"R0135_02700 SIMPL domain-containing protein\tK09807 K09807; uncharacterized protein" }, { "name":"R0135_03450 nqrM; (GenBank) (Na+)-NQR maturation NqrM\tK05952 K05952; uncharacterized protein" }, { "name":"R0135_06630 S1-like domain-containing RNA-binding protein\tK00243 K00243; uncharacterized protein" }, { "name":"R0135_04785 DUF2309 domain-containing protein\tK09822 K09822; uncharacterized protein" }, { "name":"R0135_04955 DUF2309 domain-containing protein\tK09822 K09822; uncharacterized protein" }, { "name":"R0135_11580 yaaA; (GenBank) peroxide stress protein YaaA\tK09861 K09861; uncharacterized protein" }, { "name":"R0135_11200 UPF0149 family protein\tK09895 K09895; uncharacterized protein" }, { "name":"R0135_02325 YheU family protein\tK09898 K09898; uncharacterized protein" }, { "name":"R0135_03575 YcgL domain-containing protein\tK09902 K09902; uncharacterized protein" }, { "name":"R0135_07330 DUF1043 family protein\tK09908 K09908; uncharacterized protein" }, { "name":"R0135_04940 DUF2058 domain-containing protein\tK09912 K09912; uncharacterized protein" }, { "name":"R0135_04240 DUF1315 family protein\tK09916 K09916; uncharacterized protein" }, { "name":"R0135_11560 GNAT family N-acetyltransferase\tK09919 K09919; uncharacterized protein" }, { "name":"R0135_12160 DUF1249 domain-containing protein\tK09920 K09920; uncharacterized protein" }, { "name":"R0135_09685 DUF484 family protein\tK09921 K09921; uncharacterized protein" }, { "name":"R0135_01700 FixH family protein\tK09926 K09926; uncharacterized protein" }, { "name":"R0135_06050 crosslink repair DNA glycosylase YcaQ family protein\tK09927 K09927; uncharacterized protein" }, { "name":"R0135_03430 DUF2062 domain-containing protein\tK09928 K09928; uncharacterized protein" }, { "name":"R0135_04655 putative DNA-binding domain-containing protein\tK09929 K09929; uncharacterized protein" }, { "name":"R0135_04660 DUF692 domain-containing protein\tK09930 K09930; uncharacterized protein" }, { "name":"R0135_04045 TIGR04282 family arsenosugar biosynthesis glycosyltransferase\tK09931 K09931; uncharacterized protein" }, { "name":"R0135_14990 DUF2065 domain-containing protein\tK09937 K09937; uncharacterized protein" }, { "name":"R0135_17425 DUF2066 domain-containing protein\tK09938 K09938; uncharacterized protein" }, { "name":"R0135_08495 DUF1415 domain-containing protein\tK09941 K09941; uncharacterized protein" }, { "name":"R0135_15965 YegP family protein\tK09946 K09946; uncharacterized protein" }, { "name":"R0135_00105 DUF1244 domain-containing protein\tK09948 K09948; uncharacterized protein" }, { "name":"R0135_07940 DUF2237 domain-containing protein\tK09966 K09966; uncharacterized protein" }, { "name":"R0135_13955 DUF1993 domain-containing protein\tK09983 K09983; uncharacterized protein" }, { "name":"R0135_03030 DUF1285 domain-containing protein\tK09986 K09986; uncharacterized protein" }, { "name":"R0135_03560 VWA domain-containing protein\tK09989 K09989; uncharacterized protein" }, { "name":"R0135_12075 DUF47 family protein\tK07220 K07220; uncharacterized protein" }, { "name":"R0135_13035 ELM1\/GtrOC1 family putative glycosyltransferase\tK07276 K07276; uncharacterized protein" } ] } ] } ] } ] }