{
	"name":"cvf04121",
	"children":[
	{
		"name":"Ubiquitins and ubiquitin-like proteins",
		"children":[
		{
			"name":"Ubiquitins",
			"children":[
			{
				"name":"104282178 UBC; polyubiquitin-C\tK08770 UBB_C; ubiquitin B\/C"
			},
			{
				"name":"104284384 UBB; polyubiquitin-B isoform X1\tK08770 UBB_C; ubiquitin B\/C"
			},
			{
				"name":"104284299 UBA52; ubiquitin-60S ribosomal protein L40\tK02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e"
			},
			{
				"name":"104287369 RPS27A; ubiquitin-40S ribosomal protein S27a\tK02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae"
			}
			]
		},
		{
			"name":"Ubiquitin-like proteins (UBLs)",
			"children":[
			{
				"name":"104281914 SUMO2; small ubiquitin-related modifier 2\tK12160 SUMO; small ubiquitin-related modifier"
			},
			{
				"name":"104290998 SUMO1; small ubiquitin-related modifier 1\tK12160 SUMO; small ubiquitin-related modifier"
			},
			{
				"name":"104293577 small ubiquitin-related modifier 3-like\tK12160 SUMO; small ubiquitin-related modifier"
			},
			{
				"name":"104294473 GABARAPL2; gamma-aminobutyric acid receptor-associated protein-like 2\tK08341 GABARAP; GABA(A) receptor-associated protein"
			},
			{
				"name":"104294543 GABARAPL1; gamma-aminobutyric acid receptor-associated protein-like 1\tK08341 GABARAP; GABA(A) receptor-associated protein"
			},
			{
				"name":"104289169 URM1; ubiquitin-related modifier 1\tK12161 URM1; ubiquitin related modifier 1"
			},
			{
				"name":"104289464 UFM1; ubiquitin-fold modifier 1\tK12162 UFM1; ubiquitin-fold modifier 1"
			},
			{
				"name":"104284505 UBL3; ubiquitin-like protein 3\tK28515 UBL3; membrane-anchored ubiquitin-fold protein"
			},
			{
				"name":"104289733 ZFAND4; LOW QUALITY PROTEIN: AN1-type zinc finger protein 4\tK12163 ZFAND4; AN1-type zinc finger protein 4"
			}
			]
		}
		]
	},
	{
		"name":"Ubiquitin-activating enzymes (E1)",
		"children":[
		{
			"name":"Ubiquitin activating enzyme"
		},
		{
			"name":"UBL-activating enzymes",
			"children":[
			{
				"name":"104287027 SAE1; SUMO-activating enzyme subunit 1\tK10684 UBLE1A; ubiquitin-like 1-activating enzyme E1 A [EC:6.2.1.45]"
			},
			{
				"name":"104283246 UBA2; SUMO-activating enzyme subunit 2\tK10685 UBLE1B; ubiquitin-like 1-activating enzyme E1 B [EC:6.2.1.45]"
			},
			{
				"name":"104285168 UBA3; NEDD8-activating enzyme E1 catalytic subunit isoform X1\tK10686 UBA3; NEDD8-activating enzyme E1 [EC:6.2.1.64]"
			},
			{
				"name":"104283241 NAE1; NEDD8-activating enzyme E1 regulatory subunit\tK04532 NAE1; NEDD8-activating enzyme E1 regulatory subunit"
			},
			{
				"name":"104293936 MOCS3; adenylyltransferase and sulfurtransferase MOCS3\tK11996 MOCS3; adenylyltransferase and sulfurtransferase [EC:2.7.7.80 2.8.1.11]"
			},
			{
				"name":"104295238 UBA5; ubiquitin-like modifier-activating enzyme 5\tK12164 UBA5; ubiquitin-like modifier-activating enzyme 5"
			},
			{
				"name":"104282987 UBA6; ubiquitin-like modifier-activating enzyme 6\tK10699 UBE1L2; ubiquitin-activating enzyme E1-like protein 2 [EC:6.2.1.45]"
			},
			{
				"name":"104290779 ATG7; ubiquitin-like modifier-activating enzyme ATG7\tK08337 ATG7; ubiquitin-like modifier-activating enzyme ATG7"
			}
			]
		}
		]
	},
	{
		"name":"Ubiquitin-conjugating enzymes (E2)",
		"children":[
		{
			"name":"Ubiquitin-conjugating enzymes",
			"children":[
			{
				"name":"104290258 UBE2A; ubiquitin-conjugating enzyme E2 A\tK10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]"
			},
			{
				"name":"104291636 UBE2B; ubiquitin-conjugating enzyme E2 B\tK10574 UBE2B; ubiquitin-conjugating enzyme E2 B [EC:2.3.2.23]"
			},
			{
				"name":"104286861 UBE2D3; ubiquitin-conjugating enzyme E2 D3 isoform X1\tK06689 UBE2D; ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]"
			},
			{
				"name":"104286986 UBE2D1; ubiquitin-conjugating enzyme E2 D1 isoform X1\tK06689 UBE2D; ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]"
			},
			{
				"name":"104291457 UBE2D2; ubiquitin-conjugating enzyme E2 D2\tK06689 UBE2D; ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]"
			},
			{
				"name":"104286967 UBE2E3; ubiquitin-conjugating enzyme E2 E3 isoform X1\tK20217 UBE2E; ubiquitin-conjugating enzyme E2 E [EC:2.3.2.23]"
			},
			{
				"name":"104289904 ubiquitin-conjugating enzyme E2 E1 isoform X1\tK20217 UBE2E; ubiquitin-conjugating enzyme E2 E [EC:2.3.2.23]"
			},
			{
				"name":"104286573 UBE2G1; ubiquitin-conjugating enzyme E2 G1\tK10575 UBE2G1; ubiquitin-conjugating enzyme E2 G1 [EC:2.3.2.23]"
			},
			{
				"name":"104293565 UBE2G2; ubiquitin-conjugating enzyme E2 G2\tK04555 UBE2G2; ubiquitin-conjugating enzyme E2 G2 [EC:2.3.2.23]"
			},
			{
				"name":"104284674 UBE2H; ubiquitin-conjugating enzyme E2 H\tK10576 UBE2H; ubiquitin-conjugating enzyme E2 H [EC:2.3.2.23]"
			},
			{
				"name":"104288665 UBE2J1; ubiquitin-conjugating enzyme E2 J1\tK10578 UBE2J1; ubiquitin-conjugating enzyme E2 J1 [EC:2.3.2.23]"
			},
			{
				"name":"104290483 UBE2J2; ubiquitin-conjugating enzyme E2 J2 isoform X1\tK04554 UBE2J2; ubiquitin-conjugating enzyme E2 J2 [EC:2.3.2.23]"
			},
			{
				"name":"104286363 UBE2K; ubiquitin-conjugating enzyme E2 K\tK04649 UBE2K; ubiquitin-conjugating enzyme (huntingtin interacting protein 2) [EC:2.3.2.23]"
			},
			{
				"name":"104289216 UBE2L3; ubiquitin-conjugating enzyme E2 L3\tK04552 UBE2L3; ubiquitin-conjugating enzyme E2 L3 [EC:2.3.2.23]"
			},
			{
				"name":"104284328 UBE2N; ubiquitin-conjugating enzyme E2 N\tK10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]"
			},
			{
				"name":"104284119 UBE2O; LOW QUALITY PROTEIN: E2\/E3 hybrid ubiquitin-protein ligase UBE2O\tK10581 UBE2O; ubiquitin-conjugating enzyme E2 O [EC:2.3.2.24]"
			},
			{
				"name":"104285332 UBE2QL1; ubiquitin-conjugating enzyme E2Q-like protein 1\tK10582 UBE2Q; ubiquitin-conjugating enzyme E2 Q [EC:2.3.2.23]"
			},
			{
				"name":"104287978 UBE2Q2; ubiquitin-conjugating enzyme E2 Q2\tK10582 UBE2Q; ubiquitin-conjugating enzyme E2 Q [EC:2.3.2.23]"
			},
			{
				"name":"104290842 UBE2Q1; ubiquitin-conjugating enzyme E2 Q1\tK10582 UBE2Q; ubiquitin-conjugating enzyme E2 Q [EC:2.3.2.23]"
			},
			{
				"name":"104287686 ubiquitin-conjugating enzyme E2 R2\tK02207 UBE2R; ubiquitin-conjugating enzyme E2 R [EC:2.3.2.23]"
			},
			{
				"name":"104294369 CDC34; ubiquitin-conjugating enzyme E2 R1\tK02207 UBE2R; ubiquitin-conjugating enzyme E2 R [EC:2.3.2.23]"
			},
			{
				"name":"104283177 UBE2T; ubiquitin-conjugating enzyme E2 T\tK13960 UBE2T; ubiquitin-conjugating enzyme E2 T [EC:2.3.2.23]"
			},
			{
				"name":"104292498 UBE2W; ubiquitin-conjugating enzyme E2 W\tK10688 UBE2W; ubiquitin-conjugating enzyme E2 W [EC:2.3.2.23 2.3.2.25]"
			},
			{
				"name":"104292775 UBE2Z; ubiquitin-conjugating enzyme E2 Z\tK10585 UBE2Z; ubiquitin-conjugating enzyme E2 Z [EC:2.3.2.23]"
			},
			{
				"name":"104282312 BIRC6; baculoviral IAP repeat-containing protein 6\tK10586 BIRC6; baculoviral IAP repeat-containing protein 6 (apollon) [EC:2.3.2.23]"
			}
			]
		},
		{
			"name":"UBL-conjugating enzymes",
			"children":[
			{
				"name":"104295113 UBE2I; SUMO-conjugating enzyme UBC9\tK10577 UBE2I; ubiquitin-conjugating enzyme E2 I"
			},
			{
				"name":"104288715 UBE2F; NEDD8-conjugating enzyme UBE2F\tK10687 UBE2F; ubiquitin-conjugating enzyme E2 F [EC:2.3.2.34]"
			},
			{
				"name":"104287282 UBE2M; NEDD8-conjugating enzyme Ubc12\tK10579 UBE2M; ubiquitin-conjugating enzyme E2 M [EC:2.3.2.34]"
			},
			{
				"name":"104292290 ATG3; ubiquitin-like-conjugating enzyme ATG3\tK08343 ATG3; ubiquitin-like-conjugating enzyme ATG3"
			},
			{
				"name":"104288128 ATG10; ubiquitin-like-conjugating enzyme ATG10\tK17888 ATG10L; ubiquitin-like-conjugating enzyme ATG10"
			}
			]
		}
		]
	},
	{
		"name":"Ubiquitin ligases (E3)",
		"children":[
		{
			"name":"HECT type E3",
			"children":[
			{
				"name":"104284733 UBE3A; ubiquitin-protein ligase E3A\tK10587 UBE3A; ubiquitin-protein ligase E3 A [EC:2.3.2.26]"
			},
			{
				"name":"104282239 UBE3B; ubiquitin-protein ligase E3B\tK10588 UBE3B; ubiquitin-protein ligase E3 B [EC:2.3.2.26]"
			},
			{
				"name":"104288037 UBE3C; ubiquitin-protein ligase E3C\tK10589 UBE3C; ubiquitin-protein ligase E3 C [EC:2.3.2.26]"
			},
			{
				"name":"104288681 UBE3D; E3 ubiquitin-protein ligase E3D\tK20803 UBE3D; ubiquitin-protein ligase E3 D [EC:2.3.2.26]"
			},
			{
				"name":"104290161 SMURF1; E3 ubiquitin-protein ligase SMURF1\tK04678 SMURF; E3 ubiquitin ligase SMURF1\/2 [EC:2.3.2.26]"
			},
			{
				"name":"104295080 SMURF2; E3 ubiquitin-protein ligase SMURF2\tK04678 SMURF; E3 ubiquitin ligase SMURF1\/2 [EC:2.3.2.26]"
			},
			{
				"name":"104292686 ITCH; E3 ubiquitin-protein ligase Itchy homolog isoform X1\tK05632 ITCH; E3 ubiquitin-protein ligase Itchy [EC:2.3.2.26]"
			},
			{
				"name":"104292472 WWP1; NEDD4-like E3 ubiquitin-protein ligase WWP1\tK05633 WWP1; NEDD4-like E3 ubiquitin-protein ligase WWP1 [EC:2.3.2.26]"
			},
			{
				"name":"104294432 WWP2; LOW QUALITY PROTEIN: NEDD4-like E3 ubiquitin-protein ligase WWP2\tK05630 WWP2; NEDD4-like E3 ubiquitin-protein ligase WWP2 [EC:2.3.2.26]"
			},
			{
				"name":"104290793 TRIP12; E3 ubiquitin-protein ligase TRIP12 isoform X1\tK10590 TRIP12; E3 ubiquitin-protein ligase TRIP12 [EC:2.3.2.26]"
			},
			{
				"name":"104287074 NEDD4; E3 ubiquitin-protein ligase NEDD4 isoform X1\tK10591 NEDD4; E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26]"
			},
			{
				"name":"104283814 NEDD4L; E3 ubiquitin-protein ligase NEDD4-like isoform X1\tK13305 NEDD4L; E3 ubiquitin-protein ligase NEDD4-like [EC:2.3.2.26]"
			},
			{
				"name":"104288202 AREL1; apoptosis-resistant E3 ubiquitin protein ligase 1\tK22370 AREL1; apoptosis-resistant E3 ubiquitin protein ligase 1 [EC:2.3.2.26]"
			},
			{
				"name":"104292428 UBR5; E3 ubiquitin-protein ligase UBR5\tK10593 EDD1; E3 ubiquitin-protein ligase EDD1 [EC:2.3.2.26]"
			},
			{
				"name":"104288169 G2E3; G2\/M phase-specific E3 ubiquitin-protein ligase\tK22371 G2H3; G2\/M phase-specific E3 ubiquitin-protein ligase [EC:2.3.2.26]"
			},
			{
				"name":"104287952 HERC1; probable E3 ubiquitin-protein ligase HERC1\tK10594 HERC1; E3 ubiquitin-protein ligase HERC1 [EC:2.3.2.26]"
			},
			{
				"name":"104283870 E3 ubiquitin-protein ligase HERC2\tK10595 HERC2; E3 ubiquitin-protein ligase HERC2 [EC:2.3.2.26]"
			},
			{
				"name":"104294105 probable E3 ubiquitin-protein ligase HERC3\tK10614 HERC3; E3 ubiquitin-protein ligase HERC3 [EC:2.3.2.26]"
			},
			{
				"name":"104294388 HERC4; probable E3 ubiquitin-protein ligase HERC4 isoform X1\tK10615 HERC4; E3 ubiquitin-protein ligase HERC4 [EC:2.3.2.26]"
			},
			{
				"name":"104294255 HACE1; E3 ubiquitin-protein ligase HACE1\tK12166 HACE1; E3 ubiquitin-protein ligase HACE1 [EC:2.3.2.26]"
			},
			{
				"name":"104290333 HECW1; E3 ubiquitin-protein ligase HECW1\tK12167 HECW1; E3 ubiquitin-protein ligase HECW1 [EC:2.3.2.26]"
			},
			{
				"name":"104290967 HECW2; E3 ubiquitin-protein ligase HECW2\tK12168 HECW2; E3 ubiquitin-protein ligase HECW2 [EC:2.3.2.26]"
			},
			{
				"name":"104288173 HECTD1; E3 ubiquitin-protein ligase HECTD1\tK12231 HECTD1; E3 ubiquitin-protein ligase HECTD1 [EC:2.3.2.26]"
			},
			{
				"name":"104289789 HECTD2; probable E3 ubiquitin-protein ligase HECTD2\tK12232 HECTD2; E3 ubiquitin-protein ligase HECTD2 [EC:2.3.2.26]"
			},
			{
				"name":"104286274 HECTD3; E3 ubiquitin-protein ligase HECTD3\tK12233 HECTD3; E3 ubiquitin-protein ligase HECTD3 [EC:2.3.2.26]"
			},
			{
				"name":"104286275 E3 ubiquitin-protein ligase HECTD3-like\tK12233 HECTD3; E3 ubiquitin-protein ligase HECTD3 [EC:2.3.2.26]"
			},
			{
				"name":"104282227 HECTD4; LOW QUALITY PROTEIN: probable E3 ubiquitin-protein ligase HECTD4\tK17849 HECTD4; E3 ubiquitin-protein ligase HECTD4 [EC:2.3.2.26]"
			},
			{
				"name":"HECT type E3 associated proteins",
				"children":[
				{
					"name":"104286598 NDFIP2; NEDD4 family-interacting protein 2\tK25839 NDFIP; NEDD4 family-interacting protein"
				},
				{
					"name":"104291931 NDFIP1; NEDD4 family-interacting protein 1\tK25839 NDFIP; NEDD4 family-interacting protein"
				},
				{
					"name":"104293821 N4BP3; LOW QUALITY PROTEIN: NEDD4-binding protein 3\tK26473 N4BP3; NEDD4-binding protein 3"
				},
				{
					"name":"104284558 UPF0472 protein C16orf72 homolog\tK27699 HAPSTR1; HUWE1-associated protein modifying stress responses 1"
				}
				]
			}
			]
		},
		{
			"name":"U-box type E3",
			"children":[
			{
				"name":"104296108 UBE4A; LOW QUALITY PROTEIN: ubiquitin conjugation factor E4 A\tK10596 UBE4A; ubiquitin conjugation factor E4 A [EC:2.3.2.27]"
			},
			{
				"name":"104290464 UBE4B; ubiquitin conjugation factor E4 B\tK10597 UBE4B; ubiquitin conjugation factor E4 B [EC:2.3.2.27]"
			},
			{
				"name":"104287994 LOW QUALITY PROTEIN: STIP1 homology and U box-containing protein 1-like\tK09561 STUB1; STIP1 homology and U-box containing protein 1 [EC:2.3.2.27]"
			},
			{
				"name":"104289211 PPIL2; peptidyl-prolyl cis-trans isomerase-like 2\tK10598 PPIL2; peptidyl-prolyl cis-trans isomerase-like 2 [EC:5.2.1.8]"
			},
			{
				"name":"104283270 PRPF19; pre-mRNA-processing factor 19\tK10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]"
			},
			{
				"name":"104295039 E3 ubiquitin-protein ligase RBBP6-like\tK10624 RBBP6; E3 ubiquitin-protein ligase RBBP6 [EC:2.3.2.27]"
			},
			{
				"name":"104284200 UBOX5; RING finger protein 37 isoform X1\tK10600 UBOX5; U-box domain-containing protein 5 [EC:2.3.2.27]"
			}
			]
		},
		{
			"name":"Single Ring-finger type E3",
			"children":[
			{
				"name":"BRE1 proteins",
				"children":[
				{
					"name":"104285360 RNF20; E3 ubiquitin-protein ligase BRE1A\tK10696 BRE1; E3 ubiquitin-protein ligase BRE1 [EC:2.3.2.27]"
				}
				]
			},
			{
				"name":"CBL proteins",
				"children":[
				{
					"name":"104284171 CBL; E3 ubiquitin-protein ligase CBL\tK04707 CBL; E3 ubiquitin-protein ligase CBL [EC:2.3.2.27]"
				},
				{
					"name":"104285285 CBLB; E3 ubiquitin-protein ligase CBL-B\tK22517 CBLB; E3 ubiquitin-protein ligase CBL-B [EC:2.3.2.27]"
				}
				]
			},
			{
				"name":"SINA (Seven in absentia) proteins",
				"children":[
				{
					"name":"104286476 SIAH1; E3 ubiquitin-protein ligase SIAH1\tK04506 SIAH1; E3 ubiquitin-protein ligase SIAH1 [EC:2.3.2.27]"
				},
				{
					"name":"104285944 SIAH2; E3 ubiquitin-protein ligase SIAH2\tK08742 SIAH2; E3 ubiquitin-protein ligase SIAH2 [EC:2.3.2.27]"
				}
				]
			},
			{
				"name":"Ligand of Numb proteins",
				"children":[
				{
					"name":"104284486 LNX2; ligand of Numb protein X 2\tK10692 LNX1_2; ligand of Numb protein X 1\/2 [EC:2.3.2.27]"
				},
				{
					"name":"104286390 LNX1; E3 ubiquitin-protein ligase LNX isoform X1\tK10692 LNX1_2; ligand of Numb protein X 1\/2 [EC:2.3.2.27]"
				},
				{
					"name":"104287778 ligand of Numb protein X 2-like\tK10692 LNX1_2; ligand of Numb protein X 1\/2 [EC:2.3.2.27]"
				},
				{
					"name":"104282736 PDZRN4; PDZ domain-containing RING finger protein 4\tK15682 PDZRN3_4; ligand of Numb protein X 3\/4 [EC:2.3.2.27]"
				},
				{
					"name":"104285157 PDZRN3; E3 ubiquitin-protein ligase PDZRN3\tK15682 PDZRN3_4; ligand of Numb protein X 3\/4 [EC:2.3.2.27]"
				}
				]
			},
			{
				"name":"March proteins",
				"children":[
				{
					"name":"104289734 MARCH8; E3 ubiquitin-protein ligase MARCH8 isoform X1\tK10656 MARCH1_8; E3 ubiquitin-protein ligase MARCH1\/8 [EC:2.3.2.27]"
				},
				{
					"name":"104294151 MARCH1; E3 ubiquitin-protein ligase MARCH1\tK10656 MARCH1_8; E3 ubiquitin-protein ligase MARCH1\/8 [EC:2.3.2.27]"
				},
				{
					"name":"104282495 MARCH2; E3 ubiquitin-protein ligase MARCH2\tK10657 MARCH2_3; E3 ubiquitin-protein ligase MARCH2\/3 [EC:2.3.2.27]"
				},
				{
					"name":"104290595 MARCH3; E3 ubiquitin-protein ligase MARCH3\tK10657 MARCH2_3; E3 ubiquitin-protein ligase MARCH2\/3 [EC:2.3.2.27]"
				},
				{
					"name":"104285344 MARCH11; LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase MARCH11\tK10659 MARCH4_9_11; E3 ubiquitin-protein ligase MARCH4\/9\/11 [EC:2.3.2.27]"
				},
				{
					"name":"104288513 MARCH4; E3 ubiquitin-protein ligase MARCH4\tK10659 MARCH4_9_11; E3 ubiquitin-protein ligase MARCH4\/9\/11 [EC:2.3.2.27]"
				},
				{
					"name":"104289774 MARCH5; E3 ubiquitin-protein ligase MARCH5\tK10660 MARCH5; E3 ubiquitin-protein ligase MARCH5 [EC:2.3.2.27]"
				},
				{
					"name":"104285348 MARCH6; E3 ubiquitin-protein ligase MARCH6\tK10661 MARCH6; E3 ubiquitin-protein ligase MARCH6 [EC:2.3.2.27]"
				},
				{
					"name":"104286826 MARCH7; E3 ubiquitin-protein ligase MARCH7 isoform X1\tK10662 MARCH7; E3 ubiquitin-protein ligase MARCH7 [EC:2.3.2.27]"
				}
				]
			},
			{
				"name":"MDM2\/MDM4 proteins",
				"children":[
				{
					"name":"104288920 MDM2; E3 ubiquitin-protein ligase Mdm2 isoform X1\tK06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]"
				},
				{
					"name":"104289304 MDM4; LOW QUALITY PROTEIN: protein Mdm4\tK10127 MDM4; protein Mdm4"
				}
				]
			},
			{
				"name":"NFX1 proteins",
				"children":[
				{
					"name":"104295319 NFX1; LOW QUALITY PROTEIN: transcriptional repressor NF-X1\tK12236 NFX1; transcriptional repressor NF-X1"
				},
				{
					"name":"104286421 NFXL1; NF-X1-type zinc finger protein NFXL1\tK15683 NFXL1; NF-X1-type zinc finger protein NFXL1"
				}
				]
			},
			{
				"name":"Pellino proteins",
				"children":[
				{
					"name":"104286381 PELI1; E3 ubiquitin-protein ligase pellino homolog 1\tK11964 PELI; pellino [EC:2.3.2.27]"
				},
				{
					"name":"104294361 PELI2; E3 ubiquitin-protein ligase pellino homolog 2\tK11964 PELI; pellino [EC:2.3.2.27]"
				}
				]
			},
			{
				"name":"Peripheral membrane proteins",
				"children":[
				{
					"name":"104290563 PEX10; peroxisome biogenesis factor 10\tK13346 PEX10; peroxin-10 [EC:2.3.2.27]"
				},
				{
					"name":"104286529 PEX12; peroxisome assembly protein 12\tK13345 PEX12; peroxin-12"
				},
				{
					"name":"104292487 PEX2; peroxisome biogenesis factor 2\tK06664 PEX2; peroxin-2 [EC:2.3.2.27 2.3.2.36]"
				}
				]
			},
			{
				"name":"RBR proteins",
				"children":[
				{
					"name":"104287023 PARK2; E3 ubiquitin-protein ligase parkin\tK04556 PARK2; parkin [EC:2.3.2.31]"
				},
				{
					"name":"104289016 ANKIB1; ankyrin repeat and IBR domain-containing protein 1\tK11967 ANKIB1; ankyrin repeat and IBR domain-containing protein 1 [EC:2.3.2.31]"
				},
				{
					"name":"104295787 ARIH1; E3 ubiquitin-protein ligase ARIH1\tK11968 ARIH1; ariadne-1 [EC:2.3.2.31]"
				},
				{
					"name":"104293068 ARIH2; E3 ubiquitin-protein ligase ARIH2\tK11969 ARIH2; ariadne-2 [EC:2.3.2.31]"
				},
				{
					"name":"104291414 RNF14; E3 ubiquitin-protein ligase RNF14\tK11971 RNF14; E3 ubiquitin-protein ligase RNF14 [EC:2.3.2.31]"
				},
				{
					"name":"104292436 RNF19A; E3 ubiquitin-protein ligase RNF19A\tK11972 RNF19A; E3 ubiquitin-protein ligase RNF19A [EC:2.3.2.31]"
				},
				{
					"name":"104284453 RNF19B; E3 ubiquitin-protein ligase RNF19B\tK11973 RNF19B; E3 ubiquitin-protein ligase RNF19B [EC:2.3.2.31]"
				},
				{
					"name":"104282207 RNF34; E3 ubiquitin-protein ligase RNF34\tK20804 RNF34; E3 ubiquitin-protein ligase RNF34 [EC:2.3.2.31]"
				},
				{
					"name":"104286533 RFFL; E3 ubiquitin-protein ligase rififylin\tK20804 RNF34; E3 ubiquitin-protein ligase RNF34 [EC:2.3.2.31]"
				},
				{
					"name":"104293729 RNF144A; probable E3 ubiquitin-protein ligase RNF144A\tK11975 RNF144; E3 ubiquitin-protein ligase RNF144 [EC:2.3.2.31]"
				},
				{
					"name":"104295985 RNF144B; E3 ubiquitin-protein ligase RNF144B\tK11975 RNF144; E3 ubiquitin-protein ligase RNF144 [EC:2.3.2.31]"
				},
				{
					"name":"104286755 RNF168; E3 ubiquitin-protein ligase RNF168\tK20779 RNF168; E3 ubiquitin-protein ligase RNF168 [EC:2.3.2.31]"
				},
				{
					"name":"104291743 RNF169; LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase RNF169\tK20805 RNF169; E3 ubiquitin-protein ligase RNF169 [EC:2.3.2.31]"
				},
				{
					"name":"104290145 RNF216; LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase RNF216\tK11976 RNF216; E3 ubiquitin-protein ligase RNF216 [EC:2.3.2.31]"
				},
				{
					"name":"104282105 RNF217; probable E3 ubiquitin-protein ligase RNF217\tK11977 RNF217; E3 ubiquitin-protein ligase RNF217 [EC:2.3.2.31]"
				}
				]
			},
			{
				"name":"TRAF proteins",
				"children":[
				{
					"name":"104291072 TRAF2; TNF receptor-associated factor 2\tK03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]"
				},
				{
					"name":"104289397 TRAF5; TNF receptor-associated factor 5\tK09849 TRAF5; TNF receptor-associated factor 5"
				},
				{
					"name":"104295805 TRAF6; TNF receptor-associated factor 6 isoform X1\tK03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]"
				},
				{
					"name":"104295007 TRAF7; E3 ubiquitin-protein ligase TRAF7\tK10646 TRAF7; E3 ubiquitin-protein ligase TRAF7 [EC:2.3.2.27]"
				}
				]
			},
			{
				"name":"TRIM\/RBCC proteins",
				"children":[
				{
					"name":"104281929 MID2; probable E3 ubiquitin-protein ligase MID2 isoform X1\tK10647 TRIM1; midline 2 [EC:2.3.2.27]"
				},
				{
					"name":"104294122 TRIM2; tripartite motif-containing protein 2 isoform X1\tK11997 TRIM2_3; tripartite motif-containing protein 2\/3"
				},
				{
					"name":"104287008 tripartite motif-containing protein 7-like\tK12000 TRIM7; tripartite motif-containing protein 7"
				},
				{
					"name":"104287726 LOW QUALITY PROTEIN: tripartite motif-containing protein 7-like\tK12000 TRIM7; tripartite motif-containing protein 7"
				},
				{
					"name":"104287741 zinc finger protein RFP-like\tK12000 TRIM7; tripartite motif-containing protein 7"
				},
				{
					"name":"104283367 probable E3 ubiquitin-protein ligase TRIM8\tK12001 TRIM8; tripartite motif-containing protein 8 [EC:2.3.2.27]"
				},
				{
					"name":"104292154 TRIM67; tripartite motif-containing protein 67\tK10649 TRIM9_67; tripartite motif-containing protein 9\/67"
				},
				{
					"name":"104284082 TRIM13; E3 ubiquitin-protein ligase TRIM13\tK12003 TRIM13; tripartite motif-containing protein 13 [EC:2.3.2.27]"
				},
				{
					"name":"104285718 TRIM14; tripartite motif-containing protein 14\tK12004 TRIM14; tripartite motif-containing protein 14"
				},
				{
					"name":"104287271 MID1; LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase Midline-1\tK08285 TRIM18; midline 1 [EC:2.3.2.27]"
				},
				{
					"name":"104285781 TRIM23; LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase TRIM23\tK07963 TRIM23; tripartite motif-containing protein 23 [EC:2.3.2.27]"
				},
				{
					"name":"104288607 TRIM24; transcription intermediary factor 1-alpha\tK08881 TRIM24; tripartite motif-containing protein 24 [EC:2.3.2.27]"
				},
				{
					"name":"104282162 TRIM25; E3 ubiquitin\/ISG15 ligase TRIM25\tK10652 TRIM25; tripartite motif-containing protein 25 [EC:2.3.2.27]"
				},
				{
					"name":"104287283 TRIM28; transcription intermediary factor 1-beta\tK08882 TRIM28; tripartite motif-containing protein 28 [EC:2.3.2.27]"
				},
				{
					"name":"104295397 TRIM29; tripartite motif-containing protein 29\tK12010 TRIM29; tripartite motif-containing protein 29"
				},
				{
					"name":"104289138 TRIM32; LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase TRIM32\tK10607 TRIM32; tripartite motif-containing protein 32 [EC:2.3.2.27]"
				},
				{
					"name":"104289520 TRIM33; E3 ubiquitin-protein ligase TRIM33\tK08883 TRIM33; tripartite motif-containing protein 33 [EC:2.3.2.27]"
				},
				{
					"name":"104295690 TRIM35; tripartite motif-containing protein 35\tK12012 TRIM35; tripartite motif-containing protein 35"
				},
				{
					"name":"104294222 TRIM36; E3 ubiquitin-protein ligase TRIM36 isoform X1\tK12013 TRIM36; tripartite motif-containing protein 36 [EC:2.3.2.27]"
				},
				{
					"name":"104284367 TRIM37; E3 ubiquitin-protein ligase TRIM37\tK10608 TRIM37; tripartite motif-containing protein 37 [EC:2.3.2.27]"
				},
				{
					"name":"104287725 E3 ubiquitin-protein ligase TRIM39-like\tK12015 TRIM39; tripartite motif-containing protein 39 \/ bloodthirsty-related gene family protein [EC:2.3.2.27]"
				},
				{
					"name":"104289867 E3 ubiquitin-protein ligase TRIM39-like\tK12015 TRIM39; tripartite motif-containing protein 39 \/ bloodthirsty-related gene family protein [EC:2.3.2.27]"
				},
				{
					"name":"104287737 TRIM41; E3 ubiquitin-protein ligase TRIM41\tK12017 TRIM41; tripartite motif-containing protein 41 [EC:2.3.2.27]"
				},
				{
					"name":"104290975 TRIM42; LOW QUALITY PROTEIN: tripartite motif-containing protein 42\tK12018 TRIM42; tripartite motif-containing protein 42"
				},
				{
					"name":"104281878 TRIM45; tripartite motif-containing protein 45\tK12021 TRIM45; tripartite motif-containing protein 45"
				},
				{
					"name":"104287993 TRIM46; tripartite motif-containing protein 46\tK12022 TRIM46; tripartite motif-containing protein 46"
				},
				{
					"name":"104281802 TRIM47; tripartite motif-containing protein 47\tK12023 TRIM47; tripartite motif-containing protein 47"
				},
				{
					"name":"104289872 TRIM50; E3 ubiquitin-protein ligase TRIM50\tK12024 TRIM50_73_74; tripartite motif-containing protein 50\/73\/74"
				},
				{
					"name":"104286928 TRIM55; tripartite motif-containing protein 55\tK10654 TRIM55; tripartite motif-containing protein 55"
				},
				{
					"name":"104285901 TRIM59; tripartite motif-containing protein 59\tK12028 TRIM59; tripartite motif-containing protein 59"
				},
				{
					"name":"104295973 LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase TRIM62-like\tK12030 TRIM62; tripartite motif-containing protein 62 [EC:2.3.2.27]"
				},
				{
					"name":"104283972 TRIM63; E3 ubiquitin-protein ligase TRIM63\tK10655 TRIM63; tripartite motif-containing protein 63 [EC:2.3.2.27]"
				},
				{
					"name":"104281791 TRIM65; tripartite motif-containing protein 65\tK12031 TRIM65; tripartite motif-containing protein 65"
				},
				{
					"name":"104291689 TRIM66; tripartite motif-containing protein 66\tK12032 TRIM66; tripartite motif-containing protein 66"
				},
				{
					"name":"104292567 TRIM71; E3 ubiquitin-protein ligase TRIM71\tK12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]"
				}
				]
			},
			{
				"name":"UBR box proteins",
				"children":[
				{
					"name":"104289076 UBR1; E3 ubiquitin-protein ligase UBR1\tK10625 UBR1; E3 ubiquitin-protein ligase UBR1 [EC:2.3.2.27]"
				},
				{
					"name":"104289514 UBR2; E3 ubiquitin-protein ligase UBR2\tK10626 UBR2; E3 ubiquitin-protein ligase UBR2 [EC:2.3.2.27]"
				},
				{
					"name":"104294891 UBR3; E3 ubiquitin-protein ligase UBR3\tK11978 UBR3; E3 ubiquitin-protein ligase UBR3 [EC:2.3.2.27]"
				},
				{
					"name":"104290829 UBR4; LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase UBR4\tK10691 UBR4; E3 ubiquitin-protein ligase UBR4 [EC:2.3.2.27]"
				},
				{
					"name":"104295719 UBR7; putative E3 ubiquitin-protein ligase UBR7\tK11979 UBR7; E3 ubiquitin-protein ligase UBR7 [EC:2.3.2.27]"
				}
				]
			},
			{
				"name":"ATL proteins"
			},
			{
				"name":"Other single Ring-finger type E3",
				"children":[
				{
					"name":"104290354 AMFR; E3 ubiquitin-protein ligase AMFR\tK10636 AMFR; E3 ubiquitin-protein ligase AMFR [EC:2.3.2.36]"
				},
				{
					"name":"104287850 BFAR; LOW QUALITY PROTEIN: bifunctional apoptosis regulator\tK15684 BFAR; bifunctional apoptosis regulator"
				},
				{
					"name":"104290315 BIRC2; baculoviral IAP repeat-containing protein 2\tK16060 BIRC2_3; baculoviral IAP repeat-containing protein 2\/3"
				},
				{
					"name":"104290206 XIAP; E3 ubiquitin-protein ligase XIAP\tK04725 XIAP; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]"
				},
				{
					"name":"104293899 BIRC7; baculoviral IAP repeat-containing protein 7\tK16061 BIRC7_8; baculoviral IAP repeat-containing protein 7\/8"
				},
				{
					"name":"104282222 BRAP; BRCA1-associated protein\tK10632 BRAP; BRCA1-associated protein [EC:2.3.2.27]"
				},
				{
					"name":"104294439 BRCA1; LOW QUALITY PROTEIN: breast cancer type 1 susceptibility protein\tK10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]"
				},
				{
					"name":"104291608 CBLL1; E3 ubiquitin-protein ligase Hakai\tK15685 CBLL1; E3 ubiquitin-protein ligase Hakai [EC:2.3.2.27]"
				},
				{
					"name":"104289224 CHFR; E3 ubiquitin-protein ligase CHFR\tK10644 CHFR; E3 ubiquitin-protein ligase CHFR [EC:2.3.2.27]"
				},
				{
					"name":"104294746 CNOT4; CCR4-NOT transcription complex subunit 4 isoform X1\tK10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]"
				},
				{
					"name":"104286524 DTX2; probable E3 ubiquitin-protein ligase DTX2\tK06058 DTX; deltex [EC:2.3.2.27]"
				},
				{
					"name":"104287392 DTX1; E3 ubiquitin-protein ligase DTX1\tK06058 DTX; deltex [EC:2.3.2.27]"
				},
				{
					"name":"104288489 DTX3L; E3 ubiquitin-protein ligase DTX3L\tK06058 DTX; deltex [EC:2.3.2.27]"
				},
				{
					"name":"104295607 DTX4; LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase DTX4\tK06058 DTX; deltex [EC:2.3.2.27]"
				},
				{
					"name":"104287375 FANCL; E3 ubiquitin-protein ligase FANCL\tK10606 FANCL; E3 ubiquitin-protein ligase FANCL [EC:2.3.2.27]"
				},
				{
					"name":"104284929 KCMF1; E3 ubiquitin-protein ligase KCMF1\tK22376 KCMF1; E3 ubiquitin-protein ligase KCMF1 [EC:2.3.2.27]"
				},
				{
					"name":"104290942 E3 ubiquitin-protein ligase KCMF1-like\tK22376 KCMF1; E3 ubiquitin-protein ligase KCMF1 [EC:2.3.2.27]"
				},
				{
					"name":"104291124 LRSAM1; E3 ubiquitin-protein ligase LRSAM1\tK10641 LRSAM1; E3 ubiquitin-protein ligase LRSAM1 [EC:2.3.2.27]"
				},
				{
					"name":"104295189 LTN1; E3 ubiquitin-protein ligase listerin\tK22377 LTN1; E3 ubiquitin-protein ligase listerin [EC:2.3.2.27]"
				},
				{
					"name":"104287132 mitogen-activated protein kinase kinase kinase 1-like\tK04416 MAP3K1; mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25]"
				},
				{
					"name":"104294997 MAP3K1; mitogen-activated protein kinase kinase kinase 1\tK04416 MAP3K1; mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25]"
				},
				{
					"name":"104285281 MEX3C; RNA-binding E3 ubiquitin-protein ligase MEX3C\tK15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]"
				},
				{
					"name":"104287448 MEX3B; RNA-binding protein MEX3B\tK15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]"
				},
				{
					"name":"104289043 RNA-binding protein MEX3B-like\tK15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]"
				},
				{
					"name":"104291364 MEX3A; LOW QUALITY PROTEIN: RNA-binding protein MEX3A\tK15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]"
				},
				{
					"name":"104283717 MGRN1; E3 ubiquitin-protein ligase MGRN1 isoform X1\tK10604 MGRN1; E3 ubiquitin-protein ligase MGRN1 [EC:2.3.2.27]"
				},
				{
					"name":"104287918 MIB1; E3 ubiquitin-protein ligase MIB1\tK10645 MIB; E3 ubiquitin-protein ligase mind-bomb [EC:2.3.2.27]"
				},
				{
					"name":"104290499 MIB2; E3 ubiquitin-protein ligase MIB2 isoform X1\tK10645 MIB; E3 ubiquitin-protein ligase mind-bomb [EC:2.3.2.27]"
				},
				{
					"name":"104288577 MKRN1; E3 ubiquitin-protein ligase makorin-1 isoform X1\tK15687 MKRN; E3 ubiquitin-protein ligase makorin [EC:2.3.2.27]"
				},
				{
					"name":"104290253 putative E3 ubiquitin-protein ligase makorin-4\tK15687 MKRN; E3 ubiquitin-protein ligase makorin [EC:2.3.2.27]"
				},
				{
					"name":"104290772 MKRN2; probable E3 ubiquitin-protein ligase makorin-2\tK15687 MKRN; E3 ubiquitin-protein ligase makorin [EC:2.3.2.27]"
				},
				{
					"name":"104284998 mitochondrial ubiquitin ligase activator of nfkb 1-A-like\tK15688 MUL1; E3 ubiquitin-protein ligase MUL1 [EC:2.3.2.27]"
				},
				{
					"name":"104290820 MUL1; mitochondrial ubiquitin ligase activator of NFKB 1\tK15688 MUL1; E3 ubiquitin-protein ligase MUL1 [EC:2.3.2.27]"
				},
				{
					"name":"104294427 MYCBP2; LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase MYCBP2\tK10693 MYCBP2; RCR-type E3 ubiquitin transferase [EC:2.3.2.33]"
				},
				{
					"name":"104285688 MYLIP; E3 ubiquitin-protein ligase MYLIP\tK10637 MYLIP; E3 ubiquitin-protein ligase MYLIP [EC:2.3.2.27]"
				},
				{
					"name":"104283448 NEURL1; E3 ubiquitin-protein ligase NEURL1\tK01931 NEUR; protein neuralized [EC:2.3.2.27]"
				},
				{
					"name":"104283861 NEURL1B; E3 ubiquitin-protein ligase NEURL1B\tK01931 NEUR; protein neuralized [EC:2.3.2.27]"
				},
				{
					"name":"104295990 NHLRC1; E3 ubiquitin-protein ligase NHLRC1\tK10602 NHLRC1; E3 ubiquitin-protein ligase NHLRC1 [EC:2.3.2.27]"
				},
				{
					"name":"104294429 RNF219; RING finger protein 219\tK24091 OBI1; ORC ubiquitin ligase 1 [EC:2.3.2.27]"
				},
				{
					"name":"104282391 PJA2; E3 ubiquitin-protein ligase Praja-2\tK10634 PJA2; E3 ubiquitin-protein ligase Praja2 [EC:2.3.2.27]"
				},
				{
					"name":"104284522 RAD18; E3 ubiquitin-protein ligase RAD18\tK10627 RAD18; E3 ubiquitin-protein ligase RAD18 [EC:2.3.2.27]"
				},
				{
					"name":"104295804 RAG1; V(D)J recombination-activating protein 1\tK10628 RAG1; V(D)J recombination-activating protein 1 [EC:2.3.2.27]"
				},
				{
					"name":"104289272 RCHY1; RING finger and CHY zinc finger domain-containing protein 1\tK10144 RCHY1; RING finger and CHY zinc finger domain-containing protein 1 [EC:2.3.2.27]"
				},
				{
					"name":"104292847 RC3H2; roquin-2\tK15690 RC3H; RING finger and CCCH-type zinc finger domain-containing protein"
				},
				{
					"name":"104293359 RC3H1; LOW QUALITY PROTEIN: roquin-1\tK15690 RC3H; RING finger and CCCH-type zinc finger domain-containing protein"
				},
				{
					"name":"104293350 RFWD2; E3 ubiquitin-protein ligase RFWD2\tK10143 RFWD2; E3 ubiquitin-protein ligase RFWD2 [EC:2.3.2.27]"
				},
				{
					"name":"104284788 RFWD3; E3 ubiquitin-protein ligase RFWD3\tK15691 RFWD3; E3 ubiquitin-protein ligase RFWD3 [EC:2.3.2.27]"
				},
				{
					"name":"104285857 RNF2; E3 ubiquitin-protein ligase RING2\tK10695 RNF1_2; E3 ubiquitin-protein ligase RNF1\/2 [EC:2.3.2.27]"
				},
				{
					"name":"104291294 RNF4; E3 ubiquitin-protein ligase RNF4\tK22651 RNF4; E3 ubiquitin-protein ligase RNF4 [EC:2.3.2.27]"
				},
				{
					"name":"104289618 RNF185; E3 ubiquitin-protein ligase RNF185 isoform X1\tK10666 RNF5_185; E3 ubiquitin-protein ligase RNF5\/185 [EC:2.3.2.27]"
				},
				{
					"name":"104291383 RNF6; E3 ubiquitin-protein ligase RNF6\tK22753 RNF6; E3 ubiquitin-protein ligase RNF6 [EC:2.3.2.27]"
				},
				{
					"name":"104282330 RNF8; E3 ubiquitin-protein ligase RNF8\tK10667 RNF8; E3 ubiquitin-protein ligase RNF8 [EC:2.3.2.27]"
				},
				{
					"name":"104289623 RNF10; RING finger protein 10\tK26979 RNF10; E3 ubiquitin-protein ligase RNF10 [EC:2.3.2.27]"
				},
				{
					"name":"104286253 RNF11; RING finger protein 11\tK11980 RNF11; E3 ubiquitin-protein ligase RNF11"
				},
				{
					"name":"104287774 RLIM; E3 ubiquitin-protein ligase RLIM\tK16271 RLIM; E3 ubiquitin-protein ligase RLIM [EC:2.3.2.27]"
				},
				{
					"name":"104285874 RNF13; E3 ubiquitin-protein ligase RNF13\tK15692 RNF13; E3 ubiquitin-protein ligase RNF13 [EC:2.3.2.27]"
				},
				{
					"name":"104285487 RNF25; E3 ubiquitin-protein ligase RNF25\tK10640 RNF25; E3 ubiquitin-protein ligase RNF25 [EC:2.3.2.27]"
				},
				{
					"name":"104284187 RNF26; RING finger protein 26\tK15693 RNF26; E3 ubiquitin-protein ligase RNF26 [EC:2.3.2.27]"
				},
				{
					"name":"104285717 RNF38; E3 ubiquitin-protein ligase RNF38\tK19041 RNF38_44; E3 ubiquitin-protein ligase RNF38\/44 [EC:2.3.2.27]"
				},
				{
					"name":"104286378 E3 ubiquitin-protein ligase RNF38-like\tK19041 RNF38_44; E3 ubiquitin-protein ligase RNF38\/44 [EC:2.3.2.27]"
				},
				{
					"name":"104294021 E3 ubiquitin-protein ligase RNF38-like\tK19041 RNF38_44; E3 ubiquitin-protein ligase RNF38\/44 [EC:2.3.2.27]"
				},
				{
					"name":"104291811 RNF41; E3 ubiquitin-protein ligase NRDP1\tK11981 RNF41; E3 ubiquitin-protein ligase NRDP1 [EC:2.3.2.27]"
				},
				{
					"name":"104289863 RNF43; E3 ubiquitin-protein ligase RNF43\tK15694 RNF43; E3 ubiquitin-protein ligase RNF43 [EC:2.3.2.27]"
				},
				{
					"name":"104287082 RNF111; E3 ubiquitin-protein ligase Arkadia isoform X1\tK10635 RNF111; E3 ubiquitin-protein ligase Arkadia [EC:2.3.2.27]"
				},
				{
					"name":"104293820 RNF114; E3 ubiquitin-protein ligase RNF114\tK15697 RNF114; E3 ubiquitin-protein ligase RNF114 [EC:2.3.2.27]"
				},
				{
					"name":"104289964 RNF115; E3 ubiquitin-protein ligase RNF115\tK11982 RNF115_126; E3 ubiquitin-protein ligase RNF115\/126 [EC:2.3.2.27]"
				},
				{
					"name":"104294384 RNF126; E3 ubiquitin-protein ligase RNF126\tK11982 RNF115_126; E3 ubiquitin-protein ligase RNF115\/126 [EC:2.3.2.27]"
				},
				{
					"name":"104294184 RNF175; LOW QUALITY PROTEIN: RING finger protein 175\tK15698 RNF121_175; RING finger protein 121\/175"
				},
				{
					"name":"104295935 RING finger protein 121-like\tK15698 RNF121_175; RING finger protein 121\/175"
				},
				{
					"name":"104283060 RNF123; E3 ubiquitin-protein ligase RNF123\tK12169 KPC1; Kip1 ubiquitination-promoting complex protein 1 [EC:2.3.2.27]"
				},
				{
					"name":"104287296 RNF125; LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase RNF125\tK12170 RNF125; E3 ubiquitin-protein ligase RNF125 [EC:2.3.2.27]"
				},
				{
					"name":"104290195 RNF128; E3 ubiquitin-protein ligase RNF128\tK10629 RNF128; E3 ubiquitin-protein ligase RNF128 [EC:2.3.2.27]"
				},
				{
					"name":"104293111 RNF130; E3 ubiquitin-protein ligase RNF130 isoform X1\tK15701 RNF130; E3 ubiquitin-protein ligase RNF130 [EC:2.3.2.27]"
				},
				{
					"name":"104282170 RNF135; E3 ubiquitin-protein ligase RNF135\tK16272 RNF135; E3 ubiquitin-protein ligase RNF135 [EC:2.3.2.27]"
				},
				{
					"name":"104287286 RNF138; E3 ubiquitin-protein ligase RNF138\tK10668 RNF138; E3 ubiquitin-protein ligase RNF138 [EC:2.3.2.27]"
				},
				{
					"name":"104282911 RNF139; E3 ubiquitin-protein ligase RNF139\tK15703 RNF139; E3 ubiquitin-protein ligase RNF139 [EC:2.3.2.27]"
				},
				{
					"name":"104285619 RING finger protein 145-like\tK23789 RNF145; E3 ubiquitin-protein ligase RNF145 [EC:2.3.2.27]"
				},
				{
					"name":"104293675 RNF145; RING finger protein 145\tK23789 RNF145; E3 ubiquitin-protein ligase RNF145 [EC:2.3.2.27]"
				},
				{
					"name":"104282078 RNF146; E3 ubiquitin-protein ligase RNF146\tK15700 RNF146; E3 ubiquitin-protein ligase RNF146 [EC:2.3.2.27]"
				},
				{
					"name":"104284715 RNF149; E3 ubiquitin-protein ligase RNF149\tK15704 RNF149; E3 ubiquitin-protein ligase RNF149 [EC:2.3.2.27]"
				},
				{
					"name":"104285480 RNF152; E3 ubiquitin-protein ligase RNF152\tK15705 RNF152; E3 ubiquitin-protein ligase RNF152 [EC:2.3.2.27]"
				},
				{
					"name":"104295856 RNF157; RING finger protein 157\tK25192 RNF157; E3 ubiquitin-protein ligase RNF157 [EC:2.3.2.27]"
				},
				{
					"name":"104290672 RING finger protein 165-like\tK17821 RNF165; E3 ubiquitin-protein ligase RNF165 [EC:2.3.2.27]"
				},
				{
					"name":"104295055 RNF165; RING finger protein 165\tK17821 RNF165; E3 ubiquitin-protein ligase RNF165 [EC:2.3.2.27]"
				},
				{
					"name":"104290870 RNF166; RING finger protein 166\tK17044 RNF166; E3 ubiquitin-protein ligase RNF166 [EC:2.3.2.27]"
				},
				{
					"name":"104284918 RNF170; E3 ubiquitin-protein ligase RNF170 isoform X1\tK15707 RNF170; E3 ubiquitin-protein ligase RNF170 [EC:2.3.2.27]"
				},
				{
					"name":"104286225 E3 ubiquitin-protein ligase RNF170-like\tK15707 RNF170; E3 ubiquitin-protein ligase RNF170 [EC:2.3.2.27]"
				},
				{
					"name":"104293960 E3 ubiquitin-protein ligase RNF182-like\tK11983 RNF182; E3 ubiquitin-protein ligase RNF182 [EC:2.3.2.27]"
				},
				{
					"name":"104295978 RNF182; E3 ubiquitin-protein ligase RNF182\tK11983 RNF182; E3 ubiquitin-protein ligase RNF182 [EC:2.3.2.27]"
				},
				{
					"name":"104290825 RNF186; RING finger protein 186\tK25214 RNF186; E3 ubiquitin-protein ligase RNF186 [EC:2.3.2.27]"
				},
				{
					"name":"104284894 E3 ubiquitin-protein ligase RNF213-like\tK22754 RNF213; E3 ubiquitin-protein ligase RNF213 [EC:2.3.2.27]"
				},
				{
					"name":"104288083 RNF213; LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase RNF213\tK22754 RNF213; E3 ubiquitin-protein ligase RNF213 [EC:2.3.2.27]"
				},
				{
					"name":"104286283 RNF220; E3 ubiquitin-protein ligase RNF220\tK25174 RNF220; E3 ubiquitin-protein ligase RNF220 [EC:2.3.2.27]"
				},
				{
					"name":"104284357 RNFT1; RING finger and transmembrane domain-containing protein 1\tK22379 RNFT1; E3 ubiquitin-protein ligase RNFT1 [EC:2.3.2.27]"
				},
				{
					"name":"104288002 RNFT2; LOW QUALITY PROTEIN: RING finger and transmembrane domain-containing protein 2\tK28516 RNFT2; E3 ubiquitin-protein ligase RNFT2"
				},
				{
					"name":"104295745 SHPRH; E3 ubiquitin-protein ligase SHPRH\tK15710 SHPRH; E3 ubiquitin-protein ligase SHPRH [EC:5.6.2.- 2.3.2.27]"
				},
				{
					"name":"104282789 SH3RF2; putative E3 ubiquitin-protein ligase SH3RF2\tK12171 SH3RF; E3 ubiquitin-protein ligase SH3RF [EC:2.3.2.27]"
				},
				{
					"name":"104284738 SH3RF3; SH3 domain-containing RING finger protein 3\tK12171 SH3RF; E3 ubiquitin-protein ligase SH3RF [EC:2.3.2.27]"
				},
				{
					"name":"104294159 SH3RF1; E3 ubiquitin-protein ligase SH3RF1\tK12171 SH3RF; E3 ubiquitin-protein ligase SH3RF [EC:2.3.2.27]"
				},
				{
					"name":"104285934 HLTF; helicase-like transcription factor\tK15711 SMARCA3; SWI\/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A3 [EC:5.6.2. 2.3.2.27]"
				},
				{
					"name":"104283355 SYVN1; E3 ubiquitin-protein ligase synoviolin\tK10601 SYVN1; E3 ubiquitin-protein ligase synoviolin [EC:2.3.2.27]"
				},
				{
					"name":"104284263 TMEM129; LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase TM129\tK22380 TMEM129; E3 ubiquitin-protein ligase TM129 [EC:2.3.2.27]"
				},
				{
					"name":"104296047 TOPORS; E3 ubiquitin-protein ligase Topors\tK10631 TOPORS; E3 ubiquitin-protein ligase Topors [EC:2.3.2.27]"
				},
				{
					"name":"104291994 TRAIP; E3 ubiquitin-protein ligase TRAIP\tK11985 TRAIP; TRAF-interacting protein [EC:2.3.2.27]"
				},
				{
					"name":"104292042 TTC3; E3 ubiquitin-protein ligase TTC3\tK15712 TTC3; E3 ubiquitin-protein ligase TTC3 [EC:2.3.2.27]"
				},
				{
					"name":"104295423 UHRF1; E3 ubiquitin-protein ligase UHRF1\tK10638 UHRF1; E3 ubiquitin-protein ligase UHRF1 [EC:2.3.2.27]"
				},
				{
					"name":"104291434 UHRF2; E3 ubiquitin-protein ligase UHRF2\tK15713 UHRF2; E3 ubiquitin-protein ligase UHRF2 [EC:2.3.2.27]"
				},
				{
					"name":"104295562 UNKL; putative E3 ubiquitin-protein ligase UNKL\tK23047 UNKL; E3 ubiquitin-protein ligase UNKL [EC:2.3.2.27]"
				},
				{
					"name":"104295255 ZNF598; zinc finger protein 598\tK22381 ZNF598; E3 ubiquitin-protein ligase ZNF598 [EC:2.3.2.27]"
				},
				{
					"name":"104295606 ZFP91; E3 ubiquitin-protein ligase ZFP91\tK25175 ZFP91; E3 ubiquitin-protein ligase ZFP91 [EC:2.3.2.27]"
				},
				{
					"name":"104284784 ZNRF1; E3 ubiquitin-protein ligase ZNRF1\tK10694 ZNRF1_2; E3 ubiquitin-protein ligase ZNRF1\/2 [EC:2.3.2.27]"
				},
				{
					"name":"104290094 ZNRF3; E3 ubiquitin-protein ligase ZNRF3\tK16273 ZNRF3; E3 ubiquitin-protein ligase ZNRF3 [EC:2.3.2.27]"
				}
				]
			}
			]
		},
		{
			"name":"Atypical E3",
			"children":[
			{
				"name":"104291647 JADE2; protein Jade-2\tK22155 JADE2; E3 ubiquitin-protein ligase Jade-2 [EC:2.3.2.27]"
			},
			{
				"name":"104295323 E4F1; transcription factor E4F1\tK22401 E4F1; transcription factor E4F1 \/ E3 ubiquitin-protein ligase [EC:2.3.2.27]"
			},
			{
				"name":"104295512 NSMCE1; LOW QUALITY PROTEIN: non-structural maintenance of chromosomes element 1 homolog\tK22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27]"
			}
			]
		},
		{
			"name":"UBL E3 ligases",
			"children":[
			{
				"name":"104296047 TOPORS; E3 ubiquitin-protein ligase Topors\tK10631 TOPORS; E3 ubiquitin-protein ligase Topors [EC:2.3.2.27]"
			},
			{
				"name":"104284741 E3 SUMO-protein ligase RanBP2-like\tK12172 RANBP2; E3 SUMO-protein ligase RanBP2 [EC:2.3.2.-]"
			},
			{
				"name":"104292663 PIAS1; E3 SUMO-protein ligase PIAS1 isoform X1\tK04706 PIAS1; E3 SUMO-protein ligase PIAS1 [EC:2.3.2.-]"
			},
			{
				"name":"104295058 PIAS2; E3 SUMO-protein ligase PIAS2\tK16063 PIAS2; E3 SUMO-protein ligase PIAS2 [EC:2.3.2.-]"
			},
			{
				"name":"104295717 E3 SUMO-protein ligase PIAS2\tK16063 PIAS2; E3 SUMO-protein ligase PIAS2 [EC:2.3.2.-]"
			},
			{
				"name":"104289962 PIAS3; LOW QUALITY PROTEIN: E3 SUMO-protein ligase PIAS3\tK16064 PIAS3; E3 SUMO-protein ligase PIAS3 [EC:2.3.2.-]"
			},
			{
				"name":"104291639 PIAS4; E3 SUMO-protein ligase PIAS4\tK16065 PIAS4; E3 SUMO-protein ligase PIAS4 [EC:2.3.2.27]"
			},
			{
				"name":"104288087 CBX4; E3 SUMO-protein ligase CBX4\tK11452 CBX4; E3 SUMO-protein ligase CBX4 [EC:2.3.2.-]"
			},
			{
				"name":"104282878 NSMCE2; E3 SUMO-protein ligase NSE2\tK22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]"
			},
			{
				"name":"104284259 RNF212; probable E3 SUMO-protein ligase RNF212\tK25662 RNF212; E3 SUMO-protein ligase RNF212 [EC:2.3.2.-]"
			},
			{
				"name":"104290353 ZBED1; zinc finger BED domain-containing protein 1\tK24637 ZBED1; zinc finger BED domain-containing protein 1 (E3 SUMO-protein ligase ZBED1) [EC:2.3.2.-]"
			},
			{
				"name":"104281788 ZNF451; zinc finger protein 451\tK25176 ZNF451; E3 SUMO-protein ligase ZNF451 [EC:2.3.2.-]"
			},
			{
				"name":"104294166 probable E3 ubiquitin-protein ligase HERC4\tK22372 HERC5_6; E3 ISG15--protein ligase [EC:2.3.2.-]"
			},
			{
				"name":"104289975 UFL1; E3 UFM1-protein ligase 1\tK22755 UFL1; E3 UFM1-protein ligase 1 [EC:2.3.2.-]"
			},
			{
				"name":"104292714 DCUN1D2; DCN1-like protein 2\tK17822 DCUN1D1_2; DCN1-like protein 1\/2"
			},
			{
				"name":"104295536 DCUN1D1; DCN1-like protein 1\tK17822 DCUN1D1_2; DCN1-like protein 1\/2"
			},
			{
				"name":"104287821 DCUN1D3; DCN1-like protein 3\tK17823 DCUN1D3; DCN1-like protein 3"
			},
			{
				"name":"104286388 DCUN1D4; DCN1-like protein 4\tK17824 DCUN1D4_5; DCN1-like protein 4\/5"
			},
			{
				"name":"104290322 DCUN1D5; DCN1-like protein 5\tK17824 DCUN1D4_5; DCN1-like protein 4\/5"
			}
			]
		},
		{
			"name":"Multi subunit type E3",
			"children":[
			{
				"name":"SCF complex",
				"children":[
				{
					"name":"Ring finger protein"
				},
				{
					"name":"Cullin",
					"children":[
					{
						"name":"104295307 CUL1; cullin-1\tK03347 CUL1; cullin 1"
					}
					]
				},
				{
					"name":"Adaptor protein",
					"children":[
					{
						"name":"104291610 SKP1; S-phase kinase-associated protein 1\tK03094 SKP1; S-phase kinase-associated protein 1"
					}
					]
				},
				{
					"name":"Target recognizing subunit (F-box)",
					"children":[
					{
						"name":"104282617 FBXW11; F-box\/WD repeat-containing protein 11\tK03362 FBXW1_11; F-box and WD-40 domain protein 1\/11"
					},
					{
						"name":"104294620 BTRC; F-box\/WD repeat-containing protein 1A\tK03362 FBXW1_11; F-box and WD-40 domain protein 1\/11"
					},
					{
						"name":"104292869 FBXW2; F-box\/WD repeat-containing protein 2\tK10261 FBXW2; F-box and WD-40 domain protein 2"
					},
					{
						"name":"104294633 FBXW4; F-box\/WD repeat-containing protein 4\tK10262 FBXW4; F-box and WD-40 domain protein 4"
					},
					{
						"name":"104291071 FBXW5; F-box\/WD repeat-containing protein 5\tK10263 FBXW5; F-box and WD-40 domain protein 5"
					},
					{
						"name":"104284857 F-box\/WD repeat-containing protein 7-like\tK10260 FBXW7; F-box and WD-40 domain protein 7"
					},
					{
						"name":"104294118 FBXW7; LOW QUALITY PROTEIN: F-box\/WD repeat-containing protein 7\tK10260 FBXW7; F-box and WD-40 domain protein 7"
					},
					{
						"name":"104288007 FBXW8; F-box\/WD repeat-containing protein 8\tK10264 FBXW8; F-box and WD-40 domain protein 8"
					},
					{
						"name":"104281958 CDRT1; CMT1A duplicated region transcript 1 protein\tK10266 FBXW10; F-box and WD-40 domain protein 10"
					},
					{
						"name":"104294985 SKP2; S-phase kinase-associated protein 2\tK03875 SKP2; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)"
					},
					{
						"name":"104294876 FBXL20; F-box\/LRR-repeat protein 20\tK10268 FBXL2_20; F-box and leucine-rich repeat protein 2\/20"
					},
					{
						"name":"104295302 FBXL2; F-box\/LRR-repeat protein 2\tK10268 FBXL2_20; F-box and leucine-rich repeat protein 2\/20"
					},
					{
						"name":"104294419 FBXL3; F-box\/LRR-repeat protein 3\tK10269 FBXL3; F-box and leucine-rich repeat protein 3"
					},
					{
						"name":"104289972 FBXL4; F-box\/LRR-repeat protein 4\tK10270 FBXL4; F-box and leucine-rich repeat protein 4"
					},
					{
						"name":"104288763 FBXL5; F-box\/LRR-repeat protein 5\tK10271 FBXL5; F-box and leucine-rich repeat protein 5"
					},
					{
						"name":"104285310 FBXL7; F-box\/LRR-repeat protein 7\tK10273 FBXL7; F-box and leucine-rich repeat protein 7"
					},
					{
						"name":"104290402 FBXL8; F-box\/LRR-repeat protein 8\tK10274 FBXL8; F-box and leucine-rich repeat protein 8"
					},
					{
						"name":"104282208 KDM2B; lysine-specific demethylase 2B\tK10276 FBXL10_11; F-box and leucine-rich repeat protein 10\/11 [EC:1.14.11.27]"
					},
					{
						"name":"104287547 KDM2A; lysine-specific demethylase 2A\tK10276 FBXL10_11; F-box and leucine-rich repeat protein 10\/11 [EC:1.14.11.27]"
					},
					{
						"name":"104284635 FBXL13; LOW QUALITY PROTEIN: F-box\/LRR-repeat protein 13\tK10279 FBXL13; dynein regulatory complex subunit 6"
					},
					{
						"name":"104281703 FBXL14; F-box\/LRR-repeat protein 14\tK10280 FBXL14; F-box and leucine-rich repeat protein 14"
					},
					{
						"name":"104289745 FBXL15; F-box\/LRR-repeat protein 15\tK10281 FBXL15; F-box and leucine-rich repeat protein 15"
					},
					{
						"name":"104292202 FBXL16; F-box\/LRR-repeat protein 16\tK10282 FBXL16; F-box and leucine-rich repeat protein 16"
					},
					{
						"name":"104282393 FBXL17; F-box\/LRR-repeat protein 17\tK10283 FBXL17; F-box and leucine-rich repeat protein 17"
					},
					{
						"name":"104290147 FBXL18; F-box\/LRR-repeat protein 18\tK10284 FBXL18; F-box and leucine-rich repeat protein 18"
					},
					{
						"name":"104291752 FBXL21; F-box\/LRR-repeat protein 21 isoform X1\tK10287 FBXL21; F-box and leucine-rich repeat protein 21"
					},
					{
						"name":"104287985 FBXL22; F-box and leucine-rich protein 22\tK10288 FBXL22; F-box and leucine-rich repeat protein 22"
					},
					{
						"name":"104287650 CCNF; cyclin-F\tK10289 CCNF; F-box protein 1 (cyclin F)"
					},
					{
						"name":"104290530 FBXO2; F-box only protein 2\tK10099 FBXO2; F-box protein 2"
					},
					{
						"name":"104287569 FBXO3; F-box only protein 3\tK10290 FBXO3; F-box protein 3"
					},
					{
						"name":"104294969 FBXO4; F-box only protein 4\tK10291 FBXO4; F-box protein 4"
					},
					{
						"name":"104285585 FBXO5; F-box only protein 5\tK10292 FBXO5; F-box protein 5"
					},
					{
						"name":"104290529 F-box only protein 6-like\tK10100 FBXO6; F-box protein 6"
					},
					{
						"name":"104283764 FBXO7; F-box only protein 7\tK10293 FBXO7; F-box protein 7"
					},
					{
						"name":"104283795 FBXO8; F-box only protein 8\tK10294 FBXO8; F-box protein 8"
					},
					{
						"name":"104283898 FBXO9; F-box only protein 9\tK10295 FBXO9; F-box protein 9"
					},
					{
						"name":"104282459 FBXO10; F-box only protein 10\tK10296 FBXO10; F-box protein 10"
					},
					{
						"name":"104295108 FBXO11; F-box only protein 11\tK10297 FBXO11; F-box protein 11"
					},
					{
						"name":"104287195 FBXO15; F-box only protein 15\tK10298 FBXO15; F-box protein 15"
					},
					{
						"name":"104295682 FBXO16; F-box only protein 16\tK10299 FBXO16; F-box protein 16"
					},
					{
						"name":"104284621 FBXO18; F-box only protein 18\tK10300 FBH1; F-box DNA helicase 1 [EC:5.6.2.4]"
					},
					{
						"name":"104294796 LMO7; LIM domain only protein 7\tK06084 LMO7; F-box protein 20"
					},
					{
						"name":"104288009 FBXO21; F-box only protein 21\tK10301 FBXO21; F-box protein 21"
					},
					{
						"name":"104287976 FBXO22; F-box only protein 22\tK10302 FBXO22; F-box protein 22"
					},
					{
						"name":"104282909 FBXO32; F-box only protein 32\tK10305 FBXO25_32; F-box protein 25\/32"
					},
					{
						"name":"104292190 FBXO25; F-box only protein 25 isoform X1\tK10305 FBXO25_32; F-box protein 25\/32"
					},
					{
						"name":"104294691 FBXO28; F-box only protein 28\tK10306 FBXO28; F-box protein 28"
					},
					{
						"name":"104295744 FBXO30; F-box only protein 30\tK10307 FBXO30; F-box protein 30"
					},
					{
						"name":"104291928 FBXO31; F-box only protein 31 isoform X1\tK10308 FBXO31; F-box protein 31"
					},
					{
						"name":"104288247 FBXO33; F-box only protein 33\tK10310 FBXO33; F-box protein 33"
					},
					{
						"name":"104294320 FBXO34; F-box only protein 34\tK10311 FBXO34; F-box protein 34"
					},
					{
						"name":"104291119 FBXO36; F-box only protein 36\tK10312 FBXO36; F-box protein 36"
					},
					{
						"name":"104283831 FBXO38; F-box only protein 38 isoform X1\tK10313 FBXO38; F-box protein 38"
					},
					{
						"name":"104283309 FBXO39; LOW QUALITY PROTEIN: F-box only protein 39\tK10314 FBXO39; F-box protein 39"
					},
					{
						"name":"104293542 FBXO40; LOW QUALITY PROTEIN: F-box only protein 40\tK10315 FBXO40; F-box protein 40"
					},
					{
						"name":"104281811 FBXO41; F-box only protein 41\tK10316 FBXO41; F-box protein 41"
					},
					{
						"name":"104295614 FBXO42; F-box only protein 42\tK10317 FBXO42; F-box protein 42"
					},
					{
						"name":"104292438 FBXO43; F-box only protein 43\tK10318 FBXO43; F-box protein 43"
					},
					{
						"name":"104286769 FBXO45; F-box\/SPRY domain-containing protein 1\tK10319 FBXO45; F-box protein 45"
					},
					{
						"name":"104288311 FBXO47; F-box only protein 47\tK10321 FBXO47; F-box protein 47"
					},
					{
						"name":"104285467 FBXO48; F-box only protein 48\tK27313 FBXO48; F-box protein 48"
					}
					]
				}
				]
			},
			{
				"name":"Cul2 complex",
				"children":[
				{
					"name":"Ring finger protein"
				},
				{
					"name":"Cullin",
					"children":[
					{
						"name":"104295351 CUL2; cullin-2\tK03870 CUL2; cullin 2"
					}
					]
				},
				{
					"name":"Adoptor protein",
					"children":[
					{
						"name":"104292497 TCEB1; transcription elongation factor B polypeptide 1\tK03872 ELOC; elongin-C"
					},
					{
						"name":"104289730 TCEB2; LOW QUALITY PROTEIN: transcription elongation factor B polypeptide 2\tK03873 ELOB; elongin-B"
					}
					]
				},
				{
					"name":"Target recognizing subunit",
					"children":[
					{
						"name":"104284545 VHL; von Hippel-Lindau disease tumor suppressor\tK03871 VHL; von Hippel-Lindau disease tumor supressor"
					},
					{
						"name":"104294332 LRR1; leucine-rich repeat protein 1\tK10348 LRR1; LRR-repeat protein 1"
					},
					{
						"name":"104290752 protein fem-1 homolog C-like\tK25805 FEM1A_C; protein fem-1 homolog A\/C"
					},
					{
						"name":"104294221 FEM1C; protein fem-1 homolog C\tK25805 FEM1A_C; protein fem-1 homolog A\/C"
					},
					{
						"name":"104295447 FEM1A; protein fem-1 homolog A\tK25805 FEM1A_C; protein fem-1 homolog A\/C"
					},
					{
						"name":"104292664 FEM1B; protein fem-1 homolog B\tK10349 FEM1B; protein fem-1 homolog B"
					},
					{
						"name":"104291876 APPBP2; amyloid protein-binding protein 2\tK25806 APPBP2; amyloid protein-binding protein 2"
					},
					{
						"name":"104294296 KLHDC2; kelch domain-containing protein 2\tK25807 KLHDC2; kelch domain-containing protein 2"
					},
					{
						"name":"104295134 KLHDC3; kelch domain-containing protein 3\tK25808 KLHDC3; kelch domain-containing protein 3"
					},
					{
						"name":"104284672 KLHDC10; kelch domain-containing protein 10\tK25809 KLHDC10; kelch domain-containing protein 10"
					},
					{
						"name":"104286248 protein zyg-11 homolog B\tK10350 ZYG11; Zyg-11 protein"
					},
					{
						"name":"104289121 ZER1; protein zer-1 homolog\tK10350 ZYG11; Zyg-11 protein"
					},
					{
						"name":"104289763 ZSWIM8; zinc finger SWIM domain-containing protein 8\tK25207 ZSWIM8; zinc finger SWIM domain-containing protein 8"
					}
					]
				}
				]
			},
			{
				"name":"Cul3 complex",
				"children":[
				{
					"name":"Ring finger protein"
				},
				{
					"name":"Cullin",
					"children":[
					{
						"name":"104290642 CUL3; cullin-3\tK03869 CUL3; cullin 3"
					}
					]
				},
				{
					"name":"Adoptor and target recognizing subunit (BTB)",
					"children":[
					{
						"name":"104282129 KLHL1; kelch-like protein 1\tK10442 KLHL1_4_5; kelch-like protein 1\/4\/5"
					},
					{
						"name":"104283510 KLHL4; kelch-like protein 4\tK10442 KLHL1_4_5; kelch-like protein 1\/4\/5"
					},
					{
						"name":"104286359 KLHL5; kelch-like protein 5 isoform X1\tK10442 KLHL1_4_5; kelch-like protein 1\/4\/5"
					},
					{
						"name":"104291809 KLHL3; kelch-like protein 3\tK10443 KLHL2_3; kelch-like protein 2\/3"
					},
					{
						"name":"104294152 KLHL2; kelch-like protein 2\tK10443 KLHL2_3; kelch-like protein 2\/3"
					},
					{
						"name":"104282660 KLHL6; kelch-like protein 6\tK10444 KLHL6; kelch-like protein 6"
					},
					{
						"name":"104281533 KLHL7; kelch-like protein 7\tK10445 KLHL7; kelch-like protein 7"
					},
					{
						"name":"104283536 KLHL13; kelch-like protein 13 isoform X1\tK10447 KLHL9_13; kelch-like protein 9\/13"
					},
					{
						"name":"104291089 kelch-like protein 13\tK10447 KLHL9_13; kelch-like protein 9\/13"
					},
					{
						"name":"104294779 KLHL10; kelch-like protein 10\tK10448 KLHL10; kelch-like protein 10"
					},
					{
						"name":"104295591 LOW QUALITY PROTEIN: kelch-like protein 10\tK10448 KLHL10; kelch-like protein 10"
					},
					{
						"name":"104294787 KLHL11; kelch-like protein 11\tK10449 KLHL11; kelch-like protein 11"
					},
					{
						"name":"104283192 KLHL12; kelch-like protein 12\tK10450 KLHL12; kelch-like protein 12"
					},
					{
						"name":"104287291 KLHL14; kelch-like protein 14\tK10451 KLHL14; kelch-like protein 14"
					},
					{
						"name":"104293594 KLHL15; kelch-like protein 15\tK10452 KLHL15; kelch-like protein 15"
					},
					{
						"name":"104291192 GAN; gigaxonin\tK10453 KLHL16; kelch-like protein 16 (gigaxonin)"
					},
					{
						"name":"104290476 KLHL17; kelch-like protein 17\tK10454 KLHL17; kelch-like protein 17 (actinfilin)"
					},
					{
						"name":"104289687 KLHL18; kelch-like protein 18\tK10455 KLHL18; kelch-like protein 18"
					},
					{
						"name":"104282683 KEAP1; kelch-like ECH-associated protein 1\tK10456 KLHL19; kelch-like protein 19"
					},
					{
						"name":"104293335 KLHL20; kelch-like protein 20\tK10457 KLHL20; kelch-like protein 20"
					},
					{
						"name":"104285613 KLHL21; kelch-like protein 21\tK10458 KLHL21; kelch-like protein 21"
					},
					{
						"name":"104293689 KLHL22; kelch-like protein 22\tK10459 KLHL22; kelch-like protein 22"
					},
					{
						"name":"104294895 kelch-like protein 23\tK10460 KLHL23; kelch-like protein 23"
					},
					{
						"name":"104282659 KLHL24; kelch-like protein 24\tK10461 KLHL24_35; kelch-like protein 24\/35"
					},
					{
						"name":"104291713 KLHL35; kelch-like protein 35\tK10461 KLHL24_35; kelch-like protein 24\/35"
					},
					{
						"name":"104285761 ENC1; ectoderm-neural cortex protein 1\tK10462 KLHL25_37; kelch-like protein 25\/37 (ectoderm-neural cortex protein)"
					},
					{
						"name":"104288388 KLHL25; kelch-like protein 25\tK10462 KLHL25_37; kelch-like protein 25\/37 (ectoderm-neural cortex protein)"
					},
					{
						"name":"104295403 ectoderm-neural cortex protein 1-like\tK10462 KLHL25_37; kelch-like protein 25\/37 (ectoderm-neural cortex protein)"
					},
					{
						"name":"104288972 KLHL26; kelch-like protein 26\tK10463 KLHL26; kelch-like protein 26"
					},
					{
						"name":"104286104 IPP; actin-binding protein IPP\tK13956 IPP; actin-binding protein IPP"
					},
					{
						"name":"104294292 KLHL28; kelch-like protein 28\tK10464 KLHL28; kelch-like protein 28"
					},
					{
						"name":"104286692 KLHL29; kelch-like protein 29\tK10465 KLHL29; kelch-like protein 29"
					},
					{
						"name":"104293555 KLHL30; kelch-like protein 30\tK10466 KLHL30; kelch-like protein 30"
					},
					{
						"name":"104283895 KLHL31; kelch-like protein 31\tK10467 KLHL31; kelch-like protein 31"
					},
					{
						"name":"104284436 kelch-like protein 31\tK10467 KLHL31; kelch-like protein 31"
					},
					{
						"name":"104289971 KLHL32; kelch-like protein 32 isoform X1\tK10468 KLHL32; kelch-like protein 32"
					},
					{
						"name":"104282515 KLHL33; kelch-like protein 33\tK13957 KLHL33; kelch-like protein 33"
					},
					{
						"name":"104293587 KLHL34; kelch-like protein 34\tK10469 KLHL34; kelch-like protein 34"
					},
					{
						"name":"104282816 KLHL36; kelch-like protein 36\tK13958 KLHL36; kelch-like protein 36"
					},
					{
						"name":"104282870 KLHL38; kelch-like protein 38\tK13959 KLHL38; kelch-like protein 38"
					},
					{
						"name":"104283621 KLHL42; kelch-like protein 42\tK27973 KLHL42; kelch-like protein 42"
					},
					{
						"name":"104287488 KBTBD2; kelch repeat and BTB domain-containing protein 2\tK10470 KBTBD2; kelch repeat and BTB domain-containing protein 2"
					},
					{
						"name":"104291654 KBTBD3; kelch repeat and BTB domain-containing protein 3\tK10471 KBTBD3; kelch repeat and BTB domain-containing protein 3"
					},
					{
						"name":"104295842 KBTBD4; kelch repeat and BTB domain-containing protein 4\tK10472 KBTBD4; kelch repeat and BTB domain-containing protein 4"
					},
					{
						"name":"104282401 KLHL40; kelch-like protein 40\tK10473 KBTBD5_10; kelch repeat and BTB domain-containing protein 5\/10"
					},
					{
						"name":"104294899 KLHL41; kelch-like protein 41\tK10473 KBTBD5_10; kelch repeat and BTB domain-containing protein 5\/10"
					},
					{
						"name":"104285171 KBTBD8; kelch repeat and BTB domain-containing protein 8\tK10475 KBTBD8; kelch repeat and BTB domain-containing protein 8"
					},
					{
						"name":"104290710 KBTBD12; kelch repeat and BTB domain-containing protein 12\tK21912 KBTBD12; kelch repeat and BTB domain-containing protein 12"
					},
					{
						"name":"104288643 KBTBD13; kelch repeat and BTB domain-containing protein 13\tK21913 KBTBD13; kelch repeat and BTB domain-containing protein 13"
					},
					{
						"name":"104287414 BTBD1; BTB\/POZ domain-containing protein 1\tK10477 BTBD1_2; BTB\/POZ domain-containing protein 1\/2"
					},
					{
						"name":"104288914 BTBD2; BTB\/POZ domain-containing protein 2\tK10477 BTBD1_2; BTB\/POZ domain-containing protein 1\/2"
					},
					{
						"name":"104287345 BTBD3; BTB\/POZ domain-containing protein 3\tK10478 BTBD3_6; BTB\/POZ domain-containing protein 3\/6"
					},
					{
						"name":"104291893 BTB\/POZ domain-containing protein 6\tK10478 BTBD3_6; BTB\/POZ domain-containing protein 3\/6"
					},
					{
						"name":"104295626 BTBD7; BTB\/POZ domain-containing protein 7 isoform X1\tK10479 BTBD7; BTB\/POZ domain-containing protein 7"
					},
					{
						"name":"104286171 uncharacterized protein KIAA1107-like\tK10480 BTBD8; BTB\/POZ domain-containing protein 8"
					},
					{
						"name":"104282333 BTBD9; BTB\/POZ domain-containing protein 9\tK10481 BTBD9; BTB\/POZ domain-containing protein 9"
					},
					{
						"name":"104293176 BTBD10; BTB\/POZ domain-containing protein 10 isoform X1\tK10482 BTBD10; BTB\/POZ domain-containing protein 10"
					},
					{
						"name":"104283772 BTBD11; ankyrin repeat and BTB\/POZ domain-containing protein BTBD11\tK10483 BTBD11; BTB\/POZ domain-containing protein 11"
					},
					{
						"name":"104283722 SLX4; structure-specific endonuclease subunit SLX4\tK10484 BTBD12; structure-specific endonuclease subunit SLX4 (BTB\/POZ domain-containing protein 12)"
					},
					{
						"name":"104293468 GMCL1; germ cell-less protein-like 1\tK10485 BTBD13; BTB\/POZ domain-containing protein 13 (germ cell-less protein-like 1)"
					},
					{
						"name":"104292838 NACC2; nucleus accumbens-associated protein 2\tK10486 BTBD14; BTB\/POZ domain-containing protein 14"
					},
					{
						"name":"104291896 ZBTB1; zinc finger and BTB domain-containing protein 1 isoform X1\tK10488 ZBTB1; zinc finger and BTB domain-containing protein 1"
					},
					{
						"name":"104285579 ZBTB2; zinc finger and BTB domain-containing protein 2\tK10489 ZBTB2; zinc finger and BTB domain-containing protein 2"
					},
					{
						"name":"104282456 ZBTB5; zinc finger and BTB domain-containing protein 5\tK10492 ZBTB5; zinc finger and BTB domain-containing protein 5"
					},
					{
						"name":"104284916 zinc finger and BTB domain-containing protein 5-like\tK10492 ZBTB5; zinc finger and BTB domain-containing protein 5"
					},
					{
						"name":"104292848 ZBTB6; zinc finger and BTB domain-containing protein 6\tK10493 ZBTB6; zinc finger and BTB domain-containing protein 6"
					},
					{
						"name":"104282766 ZBTB7A; zinc finger and BTB domain-containing protein 7A\tK10494 ZBTB7; zinc finger and BTB domain-containing protein 7"
					},
					{
						"name":"104284865 ZBTB7C; zinc finger and BTB domain-containing protein 7C\tK10494 ZBTB7; zinc finger and BTB domain-containing protein 7"
					},
					{
						"name":"104284422 zinc finger and BTB domain-containing protein 8A-like isoform X1\tK10495 ZBTB8; zinc finger and BTB domain-containing protein 8"
					},
					{
						"name":"104284423 zinc finger and BTB domain-containing protein 8A-like\tK10495 ZBTB8; zinc finger and BTB domain-containing protein 8"
					},
					{
						"name":"104284445 ZBTB8B; zinc finger and BTB domain-containing protein 8B\tK10495 ZBTB8; zinc finger and BTB domain-containing protein 8"
					},
					{
						"name":"104292555 ZBTB10; zinc finger and BTB domain-containing protein 10\tK10497 ZBTB10; zinc finger and BTB domain-containing protein 10"
					},
					{
						"name":"104292285 ZBTB11; zinc finger and BTB domain-containing protein 11\tK10498 ZBTB11; zinc finger and BTB domain-containing protein 11"
					},
					{
						"name":"104296105 ZBTB16; zinc finger and BTB domain-containing protein 16\tK10055 ZBTB16; zinc finger and BTB domain-containing protein 16"
					},
					{
						"name":"104295619 ZBTB17; zinc finger and BTB domain-containing protein 17\tK10500 ZBTB17; zinc finger and BTB domain-containing protein 17"
					},
					{
						"name":"104281861 ZBTB20; zinc finger and BTB domain-containing protein 20\tK10501 ZBTB20; zinc finger and BTB domain-containing protein 20"
					},
					{
						"name":"104294269 ZBTB24; zinc finger and BTB domain-containing protein 24\tK10503 ZBTB24; zinc finger and BTB domain-containing protein 24"
					},
					{
						"name":"104291897 ZBTB25; zinc finger and BTB domain-containing protein 25\tK10504 ZBTB25; zinc finger and BTB domain-containing protein 25"
					},
					{
						"name":"104292849 ZBTB26; zinc finger and BTB domain-containing protein 26\tK10505 ZBTB26; zinc finger and BTB domain-containing protein 26"
					},
					{
						"name":"104290201 ZBTB33; transcriptional regulator Kaiso\tK10507 ZBTB33; zinc finger and BTB domain-containing protein 33"
					},
					{
						"name":"104292864 ZBTB34; zinc finger and BTB domain-containing protein 34\tK10508 ZBTB34; zinc finger and BTB domain-containing protein 34"
					},
					{
						"name":"104293362 ZBTB37; zinc finger and BTB domain-containing protein 37\tK10509 ZBTB37; zinc finger and BTB domain-containing protein 37"
					},
					{
						"name":"104290833 ZBTB38; zinc finger and BTB domain-containing protein 38\tK10510 ZBTB38; zinc finger and BTB domain-containing protein 38"
					},
					{
						"name":"104284473 ZBTB39; zinc finger and BTB domain-containing protein 39\tK10511 ZBTB39; zinc finger and BTB domain-containing protein 39"
					},
					{
						"name":"104290697 ZBTB40; zinc finger and BTB domain-containing protein 40\tK10512 ZBTB40; zinc finger and BTB domain-containing protein 40"
					},
					{
						"name":"104286221 ZBTB41; zinc finger and BTB domain-containing protein 41\tK10513 ZBTB41; zinc finger and BTB domain-containing protein 41"
					},
					{
						"name":"104292863 ZBTB43; zinc finger and BTB domain-containing protein 43\tK10514 ZBTB43; zinc finger and BTB domain-containing protein 43"
					},
					{
						"name":"104291548 ZBTB44; zinc finger and BTB domain-containing protein 44\tK10515 ZBTB44; zinc finger and BTB domain-containing protein 44"
					},
					{
						"name":"104287285 ZBTB45; zinc finger and BTB domain-containing protein 45\tK10516 ZBTB45; zinc finger and BTB domain-containing protein 45"
					},
					{
						"name":"104293881 ZBTB46; zinc finger and BTB domain-containing protein 46\tK10517 ZBTB46; zinc finger and BTB domain-containing protein 46"
					},
					{
						"name":"104282420 ZBTB47; zinc finger and BTB domain-containing protein 47\tK10518 ZBTB47; zinc finger and BTB domain-containing protein 47"
					},
					{
						"name":"104290736 ABTB1; ankyrin repeat and BTB\/POZ domain-containing protein 1\tK10520 ABTB1; ankyrin repeat and BTB\/POZ domain-containing protein 1"
					},
					{
						"name":"104287524 ABTB2; ankyrin repeat and BTB\/POZ domain-containing protein 2\tK10521 ABTB2; ankyrin repeat and BTB\/POZ domain-containing protein 2"
					},
					{
						"name":"104285667 RHOBTB2; rho-related BTB domain-containing protein 2\tK07868 RHOBTB1_2; Rho-related BTB domain-containing protein 1\/2"
					},
					{
						"name":"104290683 RHOBTB1; rho-related BTB domain-containing protein 1\tK07868 RHOBTB1_2; Rho-related BTB domain-containing protein 1\/2"
					},
					{
						"name":"104285823 RHOBTB3; rho-related BTB domain-containing protein 3\tK07869 RHOBTB3; Rho-related BTB domain-containing protein 3"
					},
					{
						"name":"104282237 KCTD10; BTB\/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 isoform X1\tK15074 BACURD; BTB\/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein"
					},
					{
						"name":"104283289 TNFAIP1; BTB\/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2\tK15074 BACURD; BTB\/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein"
					},
					{
						"name":"104283226 KCTD15; BTB\/POZ domain-containing protein KCTD15\tK21754 KCTD1_15; BTB\/POZ domain-containing protein KCTD1\/15"
					},
					{
						"name":"104287904 KCTD1; BTB\/POZ domain-containing protein KCTD1\tK21754 KCTD1_15; BTB\/POZ domain-containing protein KCTD1\/15"
					},
					{
						"name":"104281935 KCTD2; BTB\/POZ domain-containing protein KCTD2\tK21914 KCTD2_5_17; BTB\/POZ domain-containing protein KCTD2\/5\/17"
					},
					{
						"name":"104283695 KCTD17; BTB\/POZ domain-containing protein KCTD17\tK21914 KCTD2_5_17; BTB\/POZ domain-containing protein KCTD2\/5\/17"
					},
					{
						"name":"104295533 KCTD5; BTB\/POZ domain-containing protein KCTD5\tK21914 KCTD2_5_17; BTB\/POZ domain-containing protein KCTD2\/5\/17"
					},
					{
						"name":"104294679 KCTD3; BTB\/POZ domain-containing protein KCTD3\tK21915 KCTD3; BTB\/POZ domain-containing protein KCTD3"
					},
					{
						"name":"104293065 KCTD6; BTB\/POZ domain-containing protein KCTD6\tK21916 KCTD6; BTB\/POZ domain-containing protein KCTD6"
					},
					{
						"name":"104283070 KCTD14; BTB\/POZ domain-containing protein KCTD14\tK21917 KCTD7_14; BTB\/POZ domain-containing protein KCTD7\/14"
					},
					{
						"name":"104286549 KCTD7; BTB\/POZ domain-containing protein KCTD7\tK21917 KCTD7_14; BTB\/POZ domain-containing protein KCTD7\/14"
					},
					{
						"name":"104282712 KCTD12; BTB\/POZ domain-containing protein KCTD12\tK21918 KCTD8_12_16; BTB\/POZ domain-containing protein KCTD8\/12\/16"
					},
					{
						"name":"104291331 KCTD16; BTB\/POZ domain-containing protein KCTD16\tK21918 KCTD8_12_16; BTB\/POZ domain-containing protein KCTD8\/12\/16"
					},
					{
						"name":"104285676 KCTD9; BTB\/POZ domain-containing protein KCTD9\tK21919 KCTD9; BTB\/POZ domain-containing protein KCTD9"
					},
					{
						"name":"104290981 KCTD18; BTB\/POZ domain-containing protein KCTD18\tK21921 KCTD18; BTB\/POZ domain-containing protein KCTD18"
					},
					{
						"name":"104283066 KCTD21; BTB\/POZ domain-containing protein KCTD21\tK21922 KCTD21; BTB\/POZ domain-containing protein KCTD21"
					},
					{
						"name":"104282213 DIABLO; diablo homolog, mitochondrial\tK10522 DIABLO; diablo"
					},
					{
						"name":"104292342 SPOPL; speckle-type POZ protein-like isoform X1\tK10523 SPOP; speckle-type POZ protein"
					},
					{
						"name":"104292784 SPOP; speckle-type POZ protein\tK10523 SPOP; speckle-type POZ protein"
					},
					{
						"name":"104283189 LZTR1; leucine-zipper-like transcriptional regulator 1\tK23330 LZTR1; leucine-zipper-like transcriptional regulator 1"
					}
					]
				}
				]
			},
			{
				"name":"Cul4 complex",
				"children":[
				{
					"name":"Ring finger protein"
				},
				{
					"name":"Cullin",
					"children":[
					{
						"name":"104290203 CUL4B; cullin-4B\tK10609 CUL4; cullin 4"
					},
					{
						"name":"104292735 CUL4A; cullin-4A\tK10609 CUL4; cullin 4"
					}
					]
				},
				{
					"name":"Adoptor protein",
					"children":[
					{
						"name":"104288862 DDB1; DNA damage-binding protein 1\tK10610 DDB1; DNA damage-binding protein 1"
					}
					]
				},
				{
					"name":"Target recognizing subunit (DCAF)",
					"children":[
					{
						"name":"104295853 DDB2; DNA damage-binding protein 2 isoform X1\tK10140 DDB2; DNA damage-binding protein 2"
					},
					{
						"name":"104295720 ERCC8; DNA excision repair protein ERCC-8 isoform X1\tK10570 ERCC8; DNA excision repair protein ERCC-8"
					},
					{
						"name":"104288437 DET1; DET1 homolog isoform X1\tK10571 DET1; de-etiolated-1"
					},
					{
						"name":"104293350 RFWD2; E3 ubiquitin-protein ligase RFWD2\tK10143 RFWD2; E3 ubiquitin-protein ligase RFWD2 [EC:2.3.2.27]"
					},
					{
						"name":"104292950 DDA1; DET1- and DDB1-associated protein 1\tK11792 DDA1; DET1- and DDB1-associated protein 1"
					},
					{
						"name":"104284536 CRBN; protein cereblon\tK11793 CRBN; cereblon"
					},
					{
						"name":"104292695 TRPC4AP; short transient receptor potential channel 4-associated protein\tK11796 TRPC4AP; Trpc4-associated protein"
					},
					{
						"name":"104291952 VPRBP; protein VPRBP\tK11789 DCAF1; DDB1- and CUL4-associated factor 1 [EC:2.7.11.1]"
					},
					{
						"name":"104289609 DTL; denticleless protein homolog\tK11790 DTL; denticleless"
					},
					{
						"name":"104284001 DCAF4; DDB1- and CUL4-associated factor 4 isoform X1\tK11799 DCAF4; DDB1- and CUL4-associated factor 4"
					},
					{
						"name":"104285093 DCAF5; DDB1- and CUL4-associated factor 5 isoform X1\tK11800 DCAF5; DDB1- and CUL4-associated factor 5"
					},
					{
						"name":"104290939 DCAF6; DDB1- and CUL4-associated factor 6\tK11795 DCAF6; DDB1- and CUL4-associated factor 6"
					},
					{
						"name":"104285379 DCAF7; DDB1- and CUL4-associated factor 7\tK11805 DCAF7; DDB1- and CUL4-associated factor 7"
					},
					{
						"name":"104288883 DCAF8; DDB1- and CUL4-associated factor 8\tK11804 DCAF8; DDB1- and CUL4-associated factor 8"
					},
					{
						"name":"104283923 WDTC1; WD and tetratricopeptide repeats protein 1 isoform X1\tK11807 WDTC1; WD and tetratricopeptide repeats protein 1"
					},
					{
						"name":"104282462 DCAF10; DDB1- and CUL4-associated factor 10\tK11802 DCAF10; DDB1- and CUL4-associated factor 10"
					},
					{
						"name":"104290639 DCAF12; DDB1- and CUL4-associated factor 12\tK11803 DCAF12; DDB1- and CUL4-associated factor 12"
					},
					{
						"name":"104295715 DDB1- and CUL4-associated factor 12-like\tK11803 DCAF12; DDB1- and CUL4-associated factor 12"
					},
					{
						"name":"104292507 DCAF13; DDB1- and CUL4-associated factor 13\tK11806 DCAF13; DDB1- and CUL4-associated factor 13"
					},
					{
						"name":"104288633 PHIP; PH-interacting protein\tK11797 PHIP; PH-interacting protein"
					},
					{
						"name":"104294948 DCAF17; DDB1- and CUL4-associated factor 17\tK23331 DCAF17; DDB1- and CUL4-associated factor 17"
					},
					{
						"name":"104283501 BRWD3; bromodomain and WD repeat-containing protein 3\tK11798 BRWD1_3; bromodomain and WD repeat domain containing protein 1\/3"
					},
					{
						"name":"104292016 BRWD1; bromodomain and WD repeat-containing protein 1\tK11798 BRWD1_3; bromodomain and WD repeat domain containing protein 1\/3"
					},
					{
						"name":"104294658 WDR26; WD repeat-containing protein 26\tK22382 WDR26; WD repeat-containing protein 26"
					},
					{
						"name":"104295009 WDR70; WD repeat-containing protein 70\tK24752 WDR70; WD repeat-containing protein 70"
					},
					{
						"name":"104283016 WDR76; WD repeat-containing protein 76\tK24755 WDR76; WD repeat-containing protein 76"
					}
					]
				}
				]
			},
			{
				"name":"Cul5 complex",
				"children":[
				{
					"name":"Ring finger protein",
					"children":[
					{
						"name":"104291149 RNF7; RING-box protein 2\tK10611 RBX2; RING-box protein 2"
					}
					]
				},
				{
					"name":"Cullin",
					"children":[
					{
						"name":"104291648 CUL5; cullin-5\tK10612 CUL5; cullin 5"
					}
					]
				},
				{
					"name":"Adoptor protein",
					"children":[
					{
						"name":"104292497 TCEB1; transcription elongation factor B polypeptide 1\tK03872 ELOC; elongin-C"
					},
					{
						"name":"104289730 TCEB2; LOW QUALITY PROTEIN: transcription elongation factor B polypeptide 2\tK03873 ELOB; elongin-B"
					}
					]
				},
				{
					"name":"Target recognizing subunit",
					"children":[
					{
						"name":"104291948 CISH; cytokine-inducible SH2-containing protein\tK04701 CISH; cytokine inducible SH2-containing protein"
					},
					{
						"name":"104288869 SOCS1; suppressor of cytokine signaling 1\tK04694 SOCS1; suppressor of cytokine signaling 1"
					},
					{
						"name":"104284327 SOCS2; LOW QUALITY PROTEIN: suppressor of cytokine signaling 2\tK04695 SOCS2; suppressor of cytokine signaling 2"
					},
					{
						"name":"104283146 SOCS3; suppressor of cytokine signaling 3\tK04696 SOCS3; suppressor of cytokine signaling 3"
					},
					{
						"name":"104294316 SOCS4; suppressor of cytokine signaling 4\tK04697 SOCS4; suppressor of cytokine signaling 4"
					},
					{
						"name":"104282545 SOCS5; suppressor of cytokine signaling 5\tK04698 SOCS5; suppressor of cytokine signaling 5"
					},
					{
						"name":"104286479 SOCS7; suppressor of cytokine signaling 7\tK04699 SOCS6_7; suppressor of cytokine signaling 6\/7"
					},
					{
						"name":"104290008 SOCS6; suppressor of cytokine signaling 6\tK04699 SOCS6_7; suppressor of cytokine signaling 6\/7"
					},
					{
						"name":"104287150 ASB1; ankyrin repeat and SOCS box protein 1\tK10323 ASB1; ankyrin repeat and SOCS box protein 1"
					},
					{
						"name":"104295662 ASB2; ankyrin repeat and SOCS box protein 2 isoform X1\tK10324 ASB2; ankyrin repeat and SOCS box protein 2"
					},
					{
						"name":"104287314 ASB3; ankyrin repeat and SOCS box protein 3\tK10325 ASB3; ankyrin repeat and SOCS box protein 3"
					},
					{
						"name":"104295577 ASB4; ankyrin repeat and SOCS box protein 4\tK10326 ASB4; ankyrin repeat and SOCS box protein 4"
					},
					{
						"name":"104283789 ASB5; LOW QUALITY PROTEIN: ankyrin repeat and SOCS box protein 5\tK10327 ASB5; ankyrin repeat and SOCS box protein 5"
					},
					{
						"name":"104289109 ASB6; LOW QUALITY PROTEIN: ankyrin repeat and SOCS box protein 6\tK10328 ASB6; ankyrin repeat and SOCS box protein 6"
					},
					{
						"name":"104288216 ASB7; LOW QUALITY PROTEIN: ankyrin repeat and SOCS box protein 7\tK10329 ASB7; ankyrin repeat and SOCS box protein 7"
					},
					{
						"name":"104291813 ASB8; ankyrin repeat and SOCS box protein 8\tK10330 ASB8; ankyrin repeat and SOCS box protein 8"
					},
					{
						"name":"104289990 ASB9; ankyrin repeat and SOCS box protein 9\tK10331 ASB9; ankyrin repeat and SOCS box protein 9"
					},
					{
						"name":"104290102 ASB10; ankyrin repeat and SOCS box protein 10\tK10332 ASB10; ankyrin repeat and SOCS box protein 10"
					},
					{
						"name":"104289989 ASB11; ankyrin repeat and SOCS box protein 11 isoform X1\tK10333 ASB11; ankyrin repeat and SOCS box protein 11"
					},
					{
						"name":"104282955 LOW QUALITY PROTEIN: ankyrin repeat and SOCS box protein 12-like\tK10334 ASB12; ankyrin repeat and SOCS box protein 12"
					},
					{
						"name":"104284665 ASB13; ankyrin repeat and SOCS box protein 13\tK10335 ASB13; ankyrin repeat and SOCS box protein 13"
					},
					{
						"name":"104295919 ASB14; LOW QUALITY PROTEIN: ankyrin repeat and SOCS box protein 14\tK10336 ASB14; ankyrin repeat and SOCS box protein 14"
					},
					{
						"name":"104285237 ASB15; ankyrin repeat and SOCS box protein 15\tK10337 ASB15; ankyrin repeat and SOCS box protein 15"
					},
					{
						"name":"104288728 ASB18; ankyrin repeat and SOCS box protein 18\tK10340 ASB18; ankyrin repeat and SOCS box protein 18"
					},
					{
						"name":"104283321 WSB1; WD repeat and SOCS box-containing protein 1\tK10341 WSB1; WD repeat and SOCS box-containing protein 1"
					},
					{
						"name":"104287390 WSB2; WD repeat and SOCS box-containing protein 2\tK10342 WSB2; WD repeat and SOCS box-containing protein 2"
					},
					{
						"name":"104290471 SPSB1; SPRY domain-containing SOCS box protein 1\tK10343 SPSB1_4; SPRY domain-containing SOCS box protein 1\/4"
					},
					{
						"name":"104290518 SPSB4; SPRY domain-containing SOCS box protein 4\tK10343 SPSB1_4; SPRY domain-containing SOCS box protein 1\/4"
					},
					{
						"name":"104292201 SPSB3; SPRY domain-containing SOCS box protein 3\tK10345 SPSB3; SPRY domain-containing SOCS box protein 3"
					},
					{
						"name":"104289759 RAB40B; ras-related protein Rab-40B\tK07928 RAB40; Ras-related protein Rab-40"
					},
					{
						"name":"104292206 RAB40C; ras-related protein Rab-40C\tK07928 RAB40; Ras-related protein Rab-40"
					},
					{
						"name":"104294807 RSPRY1; RING finger and SPRY domain-containing protein 1\tK23332 RSPRY1; RING finger and SPRY domain-containing protein 1"
					},
					{
						"name":"104283687 ankyrin repeat domain-containing protein 9-like\tK25208 ANKRD9; ankyrin repeat domain-containing protein 9"
					},
					{
						"name":"104291769 ANKRD9; ankyrin repeat domain-containing protein 9\tK25208 ANKRD9; ankyrin repeat domain-containing protein 9"
					},
					{
						"name":"104294335 KLHDC1; kelch domain-containing protein 1\tK25810 KLHDC1; kelch domain-containing protein 1"
					}
					]
				}
				]
			},
			{
				"name":"Cul7 complex",
				"children":[
				{
					"name":"Ring finger protein"
				},
				{
					"name":"Cullin"
				},
				{
					"name":"Adaptor protein",
					"children":[
					{
						"name":"104291610 SKP1; S-phase kinase-associated protein 1\tK03094 SKP1; S-phase kinase-associated protein 1"
					}
					]
				},
				{
					"name":"Target recognizing subunit",
					"children":[
					{
						"name":"104288007 FBXW8; F-box\/WD repeat-containing protein 8\tK10264 FBXW8; F-box and WD-40 domain protein 8"
					}
					]
				}
				]
			},
			{
				"name":"Cul8 complex",
				"children":[
				{
					"name":"Ring finger protein"
				},
				{
					"name":"Cullin"
				},
				{
					"name":"Adaptor protein"
				},
				{
					"name":"Target recognizing subunit"
				}
				]
			},
			{
				"name":"Cul9 complex",
				"children":[
				{
					"name":"Ring finger protein"
				},
				{
					"name":"Cullin",
					"children":[
					{
						"name":"104295164 CUL9; cullin-9\tK11970 CUL9; cullin 9"
					},
					{
						"name":"104296027 cullin-9-like\tK11970 CUL9; cullin 9"
					}
					]
				}
				]
			},
			{
				"name":"APC\/C",
				"children":[
				{
					"name":"Ring finger protein"
				},
				{
					"name":"Cullin",
					"children":[
					{
						"name":"104283786 ANAPC2; anaphase-promoting complex subunit 2\tK03349 APC2; anaphase-promoting complex subunit 2"
					}
					]
				},
				{
					"name":"Target recognizing subunit",
					"children":[
					{
						"name":"104286126 CDC20; cell division cycle protein 20 homolog\tK03363 CDC20; cell division cycle 20, cofactor of APC complex"
					},
					{
						"name":"104282507 FZR1; fizzy-related protein homolog isoform X1\tK03364 CDH1; cell division cycle 20-like protein 1, cofactor of APC complex"
					}
					]
				},
				{
					"name":"Other subunits",
					"children":[
					{
						"name":"104287310 ANAPC1; anaphase-promoting complex subunit 1\tK03348 APC1; anaphase-promoting complex subunit 1"
					},
					{
						"name":"104285388 CDC27; LOW QUALITY PROTEIN: cell division cycle protein 27 homolog\tK03350 APC3; anaphase-promoting complex subunit 3"
					},
					{
						"name":"104288779 ANAPC4; anaphase-promoting complex subunit 4\tK03351 APC4; anaphase-promoting complex subunit 4"
					},
					{
						"name":"104282206 ANAPC5; anaphase-promoting complex subunit 5\tK03352 APC5; anaphase-promoting complex subunit 5"
					},
					{
						"name":"104292709 CDC16; cell division cycle protein 16 homolog\tK03353 APC6; anaphase-promoting complex subunit 6"
					},
					{
						"name":"104282201 ANAPC7; LOW QUALITY PROTEIN: anaphase-promoting complex subunit 7\tK03354 APC7; anaphase-promoting complex subunit 7"
					},
					{
						"name":"104282786 CDC23; cell division cycle protein 23 homolog\tK03355 APC8; anaphase-promoting complex subunit 8"
					},
					{
						"name":"104291490 ANAPC10; anaphase-promoting complex subunit 10\tK03357 APC10; anaphase-promoting complex subunit 10"
					},
					{
						"name":"104288539 ANAPC13; anaphase-promoting complex subunit 13\tK12456 APC13; anaphase-promoting complex subunit 13"
					},
					{
						"name":"104295959 ANAPC16; anaphase-promoting complex subunit 16 isoform X1\tK25229 APC16; anaphase-promoting complex subunit 16"
					}
					]
				}
				]
			},
			{
				"name":"BRCC complex",
				"children":[
				{
					"name":"104294439 BRCA1; LOW QUALITY PROTEIN: breast cancer type 1 susceptibility protein\tK10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]"
				},
				{
					"name":"104289466 BRCA2; LOW QUALITY PROTEIN: breast cancer type 2 susceptibility protein\tK08775 BRCA2; breast cancer 2 susceptibility protein"
				},
				{
					"name":"104282590 BRCC3; lys-63-specific deubiquitinase BRCC36\tK11864 BRCC3; BRCA1\/BRCA2-containing complex subunit 3 [EC:3.4.19.-]"
				},
				{
					"name":"104288741 BARD1; BRCA1-associated RING domain protein 1\tK10683 BARD1; BRCA1-associated RING domain protein 1"
				},
				{
					"name":"104282549 BRE; BRCA1-A complex subunit BRE\tK12173 BRE; BRCA1-A complex subunit BRE"
				},
				{
					"name":"104292987 RAD51; DNA repair protein RAD51 homolog 1 isoform X1\tK04482 RAD51; DNA repair protein RAD51"
				}
				]
			},
			{
				"name":"KPC complex",
				"children":[
				{
					"name":"104283060 RNF123; E3 ubiquitin-protein ligase RNF123\tK12169 KPC1; Kip1 ubiquitination-promoting complex protein 1 [EC:2.3.2.27]"
				},
				{
					"name":"104292909 UBAC1; ubiquitin-associated domain-containing protein 1\tK12174 KPC2; Kip1 ubiquitination-promoting complex protein 2"
				}
				]
			},
			{
				"name":"LUBAC complex"
			},
			{
				"name":"CTLH complex",
				"children":[
				{
					"name":"104284216 RMND5A; protein RMD5 homolog A\tK23333 RMND5; E3 ubiquitin-protein transferase RMND5 [EC:2.3.2.27]"
				},
				{
					"name":"104294825 RANBP10; ran-binding protein 10\tK23334 RANBP9_10; Ran-binding protein 9\/10"
				},
				{
					"name":"104295979 RANBP9; ran-binding protein 9\tK23334 RANBP9_10; Ran-binding protein 9\/10"
				},
				{
					"name":"104288542 ARMC8; armadillo repeat-containing protein 8\tK23336 ARMC8; armadillo repeat-containing protein 8"
				},
				{
					"name":"104284612 MKLN1; muskelin\tK23337 MKLN1; muskelin"
				},
				{
					"name":"104284227 MAEA; macrophage erythroblast attacher isoform X1\tK18624 MAEA; macrophage erythroblast attacher"
				},
				{
					"name":"104289586 GID4; glucose-induced degradation protein 4 homolog\tK23335 GID4; glucose-induced degradation protein 4"
				},
				{
					"name":"104293902 GID8; glucose-induced degradation protein 8 homolog isoform X1\tK23338 GID8; glucose-induced degradation protein 8"
				},
				{
					"name":"104283676 YPEL5; protein yippee-like 5\tK23339 YPEL5; protein yippee-like 5"
				},
				{
					"name":"104294658 WDR26; WD repeat-containing protein 26\tK22382 WDR26; WD repeat-containing protein 26"
				}
				]
			},
			{
				"name":"ERAD complex",
				"children":[
				{
					"name":"104290354 AMFR; E3 ubiquitin-protein ligase AMFR\tK10636 AMFR; E3 ubiquitin-protein ligase AMFR [EC:2.3.2.36]"
				},
				{
					"name":"104283429 ERLIN1; erlin-1\tK23341 ERLIN; erlin"
				},
				{
					"name":"104285860 ERLIN2; erlin-2\tK23341 ERLIN; erlin"
				}
				]
			},
			{
				"name":"LMBR1L-GP78-UBAC2 complex",
				"children":[
				{
					"name":"104284811 LMBR1L; protein LMBR1L\tK25215 LMBR1L; protein LMBR1L"
				},
				{
					"name":"104290354 AMFR; E3 ubiquitin-protein ligase AMFR\tK10636 AMFR; E3 ubiquitin-protein ligase AMFR [EC:2.3.2.36]"
				},
				{
					"name":"104292571 UBAC2; ubiquitin-associated domain-containing protein 2\tK25216 UBAC2; ubiquitin-associated domain-containing protein 2"
				}
				]
			},
			{
				"name":"STUB1-CHIC2  complex",
				"children":[
				{
					"name":"104287994 LOW QUALITY PROTEIN: STIP1 homology and U box-containing protein 1-like\tK09561 STUB1; STIP1 homology and U-box containing protein 1 [EC:2.3.2.27]"
				},
				{
					"name":"104286435 CHIC2; cysteine-rich hydrophobic domain-containing protein 2\tK28185 CHIC2; cysteine-rich hydrophobic domain-containing protein 2"
				}
				]
			},
			{
				"name":"SLX5-SLX8 complex"
			},
			{
				"name":"Multi subunit type E3 associated proteins",
				"children":[
				{
					"name":"104288927 CAND1; cullin-associated NEDD8-dissociated protein 1\tK17263 CAND1; cullin-associated NEDD8-dissociated protein 1"
				},
				{
					"name":"104284527 LOW QUALITY PROTEIN: cullin-associated NEDD8-dissociated protein 1-like\tK24172 CAND2; cullin-associated NEDD8-dissociated protein 2"
				},
				{
					"name":"104293052 COMMD1; COMM domain-containing protein 1\tK22557 COMMD1; COMM domain containing 1"
				},
				{
					"name":"104285940 COMMD2; COMM domain-containing protein 2\tK22558 COMMD2; COMM domain containing 2"
				},
				{
					"name":"104290250 COMM domain-containing protein 5-like\tK22561 COMMD5; COMM domain containing 5"
				},
				{
					"name":"104294797 COMMD6; COMM domain-containing protein 6\tK22562 COMMD6; COMM domain containing 6"
				},
				{
					"name":"104293980 COMMD7; COMM domain-containing protein 7\tK22563 COMMD7; COMM domain containing 7"
				},
				{
					"name":"104286382 COMMD8; COMM domain-containing protein 8\tK22564 COMMD8; COMM domain containing 8"
				},
				{
					"name":"104295808 COMMD9; COMM domain-containing protein 9\tK22565 COMMD9; COMM domain containing 9"
				},
				{
					"name":"104291271 COMMD10; COMM domain-containing protein 10\tK22566 COMMD10; COMM domain containing 10"
				},
				{
					"name":"104284241 DDRGK1; DDRGK domain-containing protein 1\tK23344 DDRGK1; DDRGK domain-containing protein 1"
				},
				{
					"name":"104286173 GLMN; glomulin\tK23345 GLMN; glomulin"
				},
				{
					"name":"104285879 IVNS1ABP; influenza virus NS1A-binding protein\tK15046 IVNS1ABP; influenza virus NS1A-binding protein"
				},
				{
					"name":"104286768 UBXN7; UBX domain-containing protein 7\tK24350 UBXN7; UBX domain-containing protein 7"
				},
				{
					"name":"104292117 PACRG; parkin coregulated gene protein isoform X1\tK26163 PACRG; parkin coregulated gene protein"
				},
				{
					"name":"104287134 ubiquitin-associated protein 2-like\tK26545 UBAP2; ubiquitin-associated protein 2"
				},
				{
					"name":"104290640 UBAP2; LOW QUALITY PROTEIN: ubiquitin-associated protein 2\tK26545 UBAP2; ubiquitin-associated protein 2"
				},
				{
					"name":"104292246 UBAP2L; ubiquitin-associated protein 2-like\tK26545 UBAP2; ubiquitin-associated protein 2"
				},
				{
					"name":"104292599 UEVLD; ubiquitin-conjugating enzyme E2 variant 3 isoform X1\tK28518 UEVLD; ubiquitin-conjugating enzyme E2 variant 3"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Deubiquitinating enzyme (DUB)",
		"children":[
		{
			"name":"Ubiquitin-specific proteases (UBPs)",
			"children":[
			{
				"name":"UCH",
				"children":[
				{
					"name":"104286412 UCHL1; ubiquitin carboxyl-terminal hydrolase isozyme L1\tK05611 UCHL1; ubiquitin carboxyl-terminal hydrolase L1 [EC:3.4.19.12]"
				},
				{
					"name":"104291964 BAP1; ubiquitin carboxyl-terminal hydrolase BAP1\tK08588 BAP1; ubiquitin carboxyl-terminal hydrolase BAP1 [EC:3.4.19.12]"
				},
				{
					"name":"104294795 UCHL3; ubiquitin carboxyl-terminal hydrolase isozyme L3\tK05609 UCHL3; ubiquitin carboxyl-terminal hydrolase L3 [EC:3.4.19.12]"
				},
				{
					"name":"104293369 UCHL5; ubiquitin carboxyl-terminal hydrolase isozyme L5\tK05610 UCHL5; ubiquitin carboxyl-terminal hydrolase L5 [EC:3.4.19.12]"
				}
				]
			},
			{
				"name":"UBP\/USP",
				"children":[
				{
					"name":"104283995 ubiquitin carboxyl-terminal hydrolase CYLD-like\tK08601 CYLD; ubiquitin carboxyl-terminal hydrolase CYLD [EC:3.4.19.12]"
				},
				{
					"name":"104286470 CYLD; LOW QUALITY PROTEIN: ubiquitin carboxyl-terminal hydrolase CYLD\tK08601 CYLD; ubiquitin carboxyl-terminal hydrolase CYLD [EC:3.4.19.12]"
				},
				{
					"name":"104285515 USP1; ubiquitin carboxyl-terminal hydrolase 1\tK11832 USP1; ubiquitin carboxyl-terminal hydrolase 1 [EC:3.4.19.12]"
				},
				{
					"name":"104284168 USP2; ubiquitin carboxyl-terminal hydrolase 2\tK11833 USP2; ubiquitin carboxyl-terminal hydrolase 2 [EC:3.4.19.12]"
				},
				{
					"name":"104287953 USP3; ubiquitin carboxyl-terminal hydrolase 3\tK11986 USP3; ubiquitin carboxyl-terminal hydrolase 3 [EC:3.4.19.12]"
				},
				{
					"name":"104282972 USP4; ubiquitin carboxyl-terminal hydrolase 4\tK11835 USP4_11; ubiquitin carboxyl-terminal hydrolase 4\/11 [EC:3.4.19.12]"
				},
				{
					"name":"104292983 USP5; ubiquitin carboxyl-terminal hydrolase 5 isoform X1\tK11836 USP5_13; ubiquitin carboxyl-terminal hydrolase 5\/13 [EC:3.4.19.12]"
				},
				{
					"name":"104295560 USP13; ubiquitin carboxyl-terminal hydrolase 13\tK11836 USP5_13; ubiquitin carboxyl-terminal hydrolase 5\/13 [EC:3.4.19.12]"
				},
				{
					"name":"104291886 USP32; ubiquitin carboxyl-terminal hydrolase 32\tK11837 USP6_32; ubiquitin carboxyl-terminal hydrolase 6\/32 [EC:3.4.19.12]"
				},
				{
					"name":"104284553 USP7; ubiquitin carboxyl-terminal hydrolase 7\tK11838 USP7; ubiquitin carboxyl-terminal hydrolase 7 [EC:3.4.19.12]"
				},
				{
					"name":"104287419 USP8; ubiquitin carboxyl-terminal hydrolase 8 isoform X1\tK11839 USP8; ubiquitin carboxyl-terminal hydrolase 8 [EC:3.4.19.12]"
				},
				{
					"name":"104286050 USP24; ubiquitin carboxyl-terminal hydrolase 24\tK11840 USP9_24; ubiquitin carboxyl-terminal hydrolase 9\/24 [EC:3.4.19.12]"
				},
				{
					"name":"104293751 USP9X; probable ubiquitin carboxyl-terminal hydrolase FAF-X isoform X1\tK11840 USP9_24; ubiquitin carboxyl-terminal hydrolase 9\/24 [EC:3.4.19.12]"
				},
				{
					"name":"104282825 USP10; ubiquitin carboxyl-terminal hydrolase 10\tK11841 USP10; ubiquitin carboxyl-terminal hydrolase 10 [EC:3.4.19.12]"
				},
				{
					"name":"104284499 USP12; ubiquitin carboxyl-terminal hydrolase 12\tK11842 USP12_46; ubiquitin carboxyl-terminal hydrolase 12\/46 [EC:3.4.19.12]"
				},
				{
					"name":"104286432 USP46; ubiquitin carboxyl-terminal hydrolase 46\tK11842 USP12_46; ubiquitin carboxyl-terminal hydrolase 12\/46 [EC:3.4.19.12]"
				},
				{
					"name":"104287775 ubiquitin carboxyl-terminal hydrolase 12-like isoform X1\tK11842 USP12_46; ubiquitin carboxyl-terminal hydrolase 12\/46 [EC:3.4.19.12]"
				},
				{
					"name":"104287915 USP14; ubiquitin carboxyl-terminal hydrolase 14\tK11843 USP14; ubiquitin carboxyl-terminal hydrolase 14 [EC:3.4.19.12]"
				},
				{
					"name":"104288965 USP15; ubiquitin carboxyl-terminal hydrolase 15\tK21343 USP15; ubiquitin carboxyl-terminal hydrolase 15 [EC:3.4.19.12]"
				},
				{
					"name":"104289982 USP45; ubiquitin carboxyl-terminal hydrolase 45\tK11844 USP16_45; ubiquitin carboxyl-terminal hydrolase 16\/45 [EC:3.4.19.12]"
				},
				{
					"name":"104295188 USP16; LOW QUALITY PROTEIN: ubiquitin carboxyl-terminal hydrolase 16\tK11844 USP16_45; ubiquitin carboxyl-terminal hydrolase 16\/45 [EC:3.4.19.12]"
				},
				{
					"name":"104281614 USP18; ubl carboxyl-terminal hydrolase 18\tK11846 USP18_41; ubiquitin carboxyl-terminal hydrolase 18\/41 [EC:3.4.19.12]"
				},
				{
					"name":"104293086 USP19; ubiquitin carboxyl-terminal hydrolase 19\tK11847 USP19; ubiquitin carboxyl-terminal hydrolase 19 [EC:3.4.19.12]"
				},
				{
					"name":"104286133 USP33; ubiquitin carboxyl-terminal hydrolase 33 isoform X1\tK11848 USP20_33; ubiquitin carboxyl-terminal hydrolase 20\/33 [EC:3.4.19.12]"
				},
				{
					"name":"104289103 USP20; ubiquitin carboxyl-terminal hydrolase 20\tK11848 USP20_33; ubiquitin carboxyl-terminal hydrolase 20\/33 [EC:3.4.19.12]"
				},
				{
					"name":"104290136 USP22; ubiquitin carboxyl-terminal hydrolase 22 isoform X1\tK11366 USP22_27_51; ubiquitin carboxyl-terminal hydrolase 22\/27\/51 [EC:3.4.19.12]"
				},
				{
					"name":"104285414 USP25; ubiquitin carboxyl-terminal hydrolase 25\tK11849 USP25; ubiquitin carboxyl-terminal hydrolase 25 [EC:3.4.19.12]"
				},
				{
					"name":"104285304 USP37; ubiquitin carboxyl-terminal hydrolase 37\tK11850 USP26_29_37; ubiquitin carboxyl-terminal hydrolase 26\/29\/37 [EC:3.4.19.12]"
				},
				{
					"name":"104296107 USP28; ubiquitin carboxyl-terminal hydrolase 28\tK21122 USP28; ubiquitin carboxyl-terminal hydrolase 28 [EC:3.4.19.12]"
				},
				{
					"name":"104282234 USP30; ubiquitin carboxyl-terminal hydrolase 30 isoform X1\tK11851 USP30; ubiquitin carboxyl-terminal hydrolase 30 [EC:3.4.19.12]"
				},
				{
					"name":"104295071 USP31; ubiquitin carboxyl-terminal hydrolase 31\tK11852 USP31; ubiquitin carboxyl-terminal hydrolase 31 [EC:3.4.19.12]"
				},
				{
					"name":"104287380 USP34; LOW QUALITY PROTEIN: ubiquitin carboxyl-terminal hydrolase 34\tK11853 USP34; ubiquitin carboxyl-terminal hydrolase 34 [EC:3.4.19.12]"
				},
				{
					"name":"104283065 USP35; LOW QUALITY PROTEIN: ubiquitin carboxyl-terminal hydrolase 35\tK11854 USP35_38; ubiquitin carboxyl-terminal hydrolase 35\/38 [EC:3.4.19.12]"
				},
				{
					"name":"104294561 USP38; ubiquitin carboxyl-terminal hydrolase 38\tK11854 USP35_38; ubiquitin carboxyl-terminal hydrolase 35\/38 [EC:3.4.19.12]"
				},
				{
					"name":"104283149 USP36; ubiquitin carboxyl-terminal hydrolase 36\tK11855 USP36_42; ubiquitin carboxyl-terminal hydrolase 36\/42 [EC:3.4.19.12]"
				},
				{
					"name":"104287551 USP42; ubiquitin carboxyl-terminal hydrolase 42\tK11855 USP36_42; ubiquitin carboxyl-terminal hydrolase 36\/42 [EC:3.4.19.12]"
				},
				{
					"name":"104287144 USP40; ubiquitin carboxyl-terminal hydrolase 40\tK11869 USP40; ubiquitin carboxyl-terminal hydrolase 40 [EC:3.4.19.12]"
				},
				{
					"name":"104284280 USP44; ubiquitin carboxyl-terminal hydrolase 44\tK11834 USP44_49; ubiquitin carboxyl-terminal hydrolase 44\/49 [EC:3.4.19.12]"
				},
				{
					"name":"104289313 USP49; ubiquitin carboxyl-terminal hydrolase 49\tK11834 USP44_49; ubiquitin carboxyl-terminal hydrolase 44\/49 [EC:3.4.19.12]"
				},
				{
					"name":"104293170 USP47; ubiquitin carboxyl-terminal hydrolase 47\tK11857 USP47; ubiquitin carboxyl-terminal hydrolase 47 [EC:3.4.19.12]"
				},
				{
					"name":"104290899 USP48; ubiquitin carboxyl-terminal hydrolase 48\tK11858 USP48; ubiquitin carboxyl-terminal hydrolase 48 [EC:3.4.19.12]"
				},
				{
					"name":"104287459 USP50; inactive ubiquitin carboxyl-terminal hydrolase 50\tK28833 USP50; ubiquitin carboxyl-terminal hydrolase 50 [EC:3.4.19.12]"
				},
				{
					"name":"104289757 USP54; inactive ubiquitin carboxyl-terminal hydrolase 54\tK27920 USP54; ubiquitin carboxyl-terminal hydrolase 54 [EC:3.4.19.12]"
				}
				]
			},
			{
				"name":"OTU",
				"children":[
				{
					"name":"104282932 OTUB1; ubiquitin thioesterase OTUB1\tK09602 OTUB1; ubiquitin thioesterase protein OTUB1 [EC:3.4.19.12]"
				},
				{
					"name":"104290806 OTUD3; OTU domain-containing protein 3\tK13717 OTUD3; OTU domain-containing protein 3 [EC:3.4.19.12]"
				},
				{
					"name":"104292464 OTUD6B; OTU domain-containing protein 6B\tK18342 OTUD6; OTU domain-containing protein 6 [EC:3.4.19.12]"
				},
				{
					"name":"104287095 OTUD7A; OTU domain-containing protein 7A\tK11860 OTUD7A_B; OTU domain-containing protein 7 [EC:3.4.19.12]"
				},
				{
					"name":"104287479 OTUD7B; OTU domain-containing protein 7B\tK11860 OTUD7A_B; OTU domain-containing protein 7 [EC:3.4.19.12]"
				},
				{
					"name":"104285312 OTULIN; ubiquitin thioesterase otulin\tK18343 OTULIN; ubiquitin thioesterase otulin [EC:3.4.19.12]"
				},
				{
					"name":"104284020 TNFAIP3; tumor necrosis factor alpha-induced protein 3 isoform X1\tK11859 TNFAIP3; tumor necrosis factor, alpha-induced protein 3 [EC:3.4.19.12]"
				},
				{
					"name":"104286934 VCPIP1; deubiquitinating protein VCIP135\tK11861 VCPIP1; deubiquitinating protein VCIP135 [EC:3.4.19.12]"
				},
				{
					"name":"104293234 ZRANB1; LOW QUALITY PROTEIN: ubiquitin thioesterase ZRANB1\tK11862 ZRANB1; ubiquitin thioesterase ZRANB1 [EC:3.4.19.12]"
				}
				]
			},
			{
				"name":"MJD",
				"children":[
				{
					"name":"104295321 ATXN3; ataxin-3 isoform X1\tK11863 ATXN3; ataxin-3 [EC:3.4.22.-]"
				},
				{
					"name":"104283625 JOSD1; josephin-1\tK15235 JOSD; josephin [EC:3.4.19.12]"
				}
				]
			},
			{
				"name":"MINDY",
				"children":[
				{
					"name":"104287113 FAM63B; protein FAM63B\tK01309 MINDY1_2; ubiquitin carboxyl-terminal hydrolase MINDY-1\/2 [EC:3.4.19.12]"
				},
				{
					"name":"104282047 FAM188B; protein FAM188B\tK22647 MINDY3_4; ubiquitin carboxyl-terminal hydrolase MINDY-3\/4 [EC:3.4.19.12]"
				},
				{
					"name":"104288345 FAM188A; protein FAM188A\tK22647 MINDY3_4; ubiquitin carboxyl-terminal hydrolase MINDY-3\/4 [EC:3.4.19.12]"
				}
				]
			},
			{
				"name":"JAMM",
				"children":[
				{
					"name":"104282590 BRCC3; lys-63-specific deubiquitinase BRCC36\tK11864 BRCC3; BRCA1\/BRCA2-containing complex subunit 3 [EC:3.4.19.-]"
				},
				{
					"name":"104286227 MYSM1; histone H2A deubiquitinase MYSM1\tK11865 MYSM1; histone H2A deubiquitinase [EC:3.4.19.-]"
				},
				{
					"name":"104294927 PSMD14; 26S proteasome non-ATPase regulatory subunit 14\tK03030 PSMD14; 26S proteasome regulatory subunit N11"
				},
				{
					"name":"104282024 STAMBP; STAM-binding protein\tK11866 STAMBP; STAM-binding protein [EC:3.4.19.12]"
				},
				{
					"name":"104289715 STAMBPL1; AMSH-like protease\tK11867 STAMBPL1; AMSH-like protease [EC:3.4.19.12]"
				}
				]
			},
			{
				"name":"PPPDE",
				"children":[
				{
					"name":"104283916 desumoylating isopeptidase 2-like\tK22763 DESI2; deubiquitinase DESI2 [EC:3.4.19.12]"
				},
				{
					"name":"104294085 DESI2; desumoylating isopeptidase 2\tK22763 DESI2; deubiquitinase DESI2 [EC:3.4.19.12]"
				}
				]
			},
			{
				"name":"ZUFSP",
				"children":[
				{
					"name":"104291278 ZUFSP; zinc finger with UFM1-specific peptidase domain protein\tK24134 ZUP1; zinc finger-containing ubiquitin peptidase 1 [EC:3.4.19.12]"
				}
				]
			},
			{
				"name":"BRISC complex",
				"children":[
				{
					"name":"104293264 FAM175B; BRISC complex subunit Abro1\tK20799 FAM175B; BRISC complex subunit Abro1"
				},
				{
					"name":"104282590 BRCC3; lys-63-specific deubiquitinase BRCC36\tK11864 BRCC3; BRCA1\/BRCA2-containing complex subunit 3 [EC:3.4.19.-]"
				},
				{
					"name":"104282549 BRE; BRCA1-A complex subunit BRE\tK12173 BRE; BRCA1-A complex subunit BRE"
				}
				]
			}
			]
		},
		{
			"name":"UBL-specific proteases (ULPs)",
			"children":[
			{
				"name":"104291814 SENP1; sentrin-specific protease 1\tK08592 SENP1; sentrin-specific protease 1 [EC:3.4.22.68]"
			},
			{
				"name":"104295528 SENP5; sentrin-specific protease 5\tK08594 SENP5; sentrin-specific protease 5 [EC:3.4.22.68]"
			},
			{
				"name":"104295946 SENP6; sentrin-specific protease 6\tK08595 SENP6; sentrin-specific protease 6 [EC:3.4.22.68]"
			},
			{
				"name":"104292280 SENP7; sentrin-specific protease 7\tK08596 SENP7; sentrin-specific protease 7 [EC:3.4.22.68]"
			},
			{
				"name":"104295765 SENP8; sentrin-specific protease 8\tK08597 SENP8; sentrin-specific protease 8 [EC:3.4.22.68]"
			},
			{
				"name":"104294795 UCHL3; ubiquitin carboxyl-terminal hydrolase isozyme L3\tK05609 UCHL3; ubiquitin carboxyl-terminal hydrolase L3 [EC:3.4.19.12]"
			},
			{
				"name":"104295520 DESI1; desumoylating isopeptidase 1\tK22762 DESI1; desumoylating isopeptidase 1 [EC:3.4.-.-]"
			},
			{
				"name":"104284496 USPL1; SUMO-specific isopeptidase USPL1\tK23008 USPL1; SUMO-specific isopeptidase USPL1 [EC:3.4.22.-]"
			},
			{
				"name":"COP9 signalosome (CSN) complex",
				"children":[
				{
					"name":"104283113 GPS1; COP9 signalosome complex subunit 1\tK12175 GPS1; COP9 signalosome complex subunit 1"
				},
				{
					"name":"104287428 COPS2; COP9 signalosome complex subunit 2\tK12176 COPS2; COP9 signalosome complex subunit 2"
				},
				{
					"name":"104290134 COPS3; COP9 signalosome complex subunit 3\tK12177 COPS3; COP9 signalosome complex subunit 3"
				},
				{
					"name":"104288710 COPS4; COP9 signalosome complex subunit 4\tK12178 COPS4; COP9 signalosome complex subunit 4"
				},
				{
					"name":"104286922 COPS5; COP9 signalosome complex subunit 5\tK09613 COPS5; COP9 signalosome complex subunit 5 [EC:3.4.-.-]"
				},
				{
					"name":"104284953 COPS7B; COP9 signalosome complex subunit 7b isoform X1\tK12180 COPS7; COP9 signalosome complex subunit 7"
				},
				{
					"name":"104293438 COPS7A; COP9 signalosome complex subunit 7a\tK12180 COPS7; COP9 signalosome complex subunit 7"
				},
				{
					"name":"104288713 COPS8; COP9 signalosome complex subunit 8\tK12181 COPS8; COP9 signalosome complex subunit 8"
				}
				]
			}
			]
		}
		]
	}
	]
}