{
	"name":"dan03021",
	"children":[
	{
		"name":"Eukaryotic type",
		"children":[
		{
			"name":"RNA polymerase II system",
			"children":[
			{
				"name":"RNA polymerase II",
				"children":[
				{
					"name":"Core subunits",
					"children":[
					{
						"name":"6503074 DNA-directed RNA polymerase II subunit RPB1\tK03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]"
					},
					{
						"name":"6499035 DNA-directed RNA polymerase II subunit RPB2\tK03010 RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]"
					},
					{
						"name":"6502416 DNA-directed RNA polymerase II subunit RPB3\tK03011 RPB3; DNA-directed RNA polymerase II subunit RPB3"
					},
					{
						"name":"6497920 DNA-directed RNA polymerase II subunit RPB11\tK03008 RPB11; DNA-directed RNA polymerase II subunit RPB11"
					}
					]
				},
				{
					"name":"Pol II specific subunits",
					"children":[
					{
						"name":"6494686 DNA-directed RNA polymerase II subunit RPB7\tK03015 RPB7; DNA-directed RNA polymerase II subunit RPB7"
					},
					{
						"name":"6498960 DNA-directed RNA polymerase II subunit RPB9\tK03017 RPB9; DNA-directed RNA polymerase II subunit RPB9"
					}
					]
				},
				{
					"name":"Pol I, II, III common subunits",
					"children":[
					{
						"name":"6495295 DNA-directed RNA polymerases I, II, and III subunit RPABC1\tK03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1"
					},
					{
						"name":"6500033 DNA-directed RNA polymerases I, II, and III subunit RPABC2\tK03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2"
					},
					{
						"name":"6507791 DNA-directed RNA polymerases I, II, and III subunit RPABC3\tK03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3"
					},
					{
						"name":"6495477 DNA-directed RNA polymerases I, II, and III subunit RPABC4\tK03009 RPABC4; DNA-directed RNA polymerases I, II, and III subunit RPABC4"
					},
					{
						"name":"6500009 DNA-directed RNA polymerases I, II, and III subunit RPABC5\tK03007 RPABC5; DNA-directed RNA polymerases I, II, and III subunit RPABC5"
					}
					]
				},
				{
					"name":"Pol IV and V specific subunits"
				}
				]
			},
			{
				"name":"Basal transcription factors",
				"children":[
				{
					"name":"TFIIA",
					"children":[
					{
						"name":"6499076 transcription initiation factor IIA subunit 1 isoform X1\tK03122 TFIIA1; transcription initiation factor TFIIA large subunit"
					},
					{
						"name":"6501502 transcription initiation factor IIA subunit 2\tK03123 TFIIA2; transcription initiation factor TFIIA small subunit"
					}
					]
				},
				{
					"name":"TFIIB",
					"children":[
					{
						"name":"6498595 transcription initiation factor IIB\tK03124 TFIIB; transcription initiation factor TFIIB"
					}
					]
				},
				{
					"name":"TFIID",
					"children":[
					{
						"name":"6494491 TATA-box-binding protein\tK03120 TBP; transcription initiation factor TFIID TATA-box-binding protein"
					},
					{
						"name":"6497577 TBP-related factor\tK03120 TBP; transcription initiation factor TFIID TATA-box-binding protein"
					},
					{
						"name":"6499969 transcription initiation factor TFIID subunit 1 isoform X1\tK03125 TAF1; transcription initiation factor TFIID subunit 1 [EC:2.3.1.48 2.7.11.1]"
					},
					{
						"name":"6506493 transcription initiation factor TFIID subunit 2\tK03128 TAF2; transcription initiation factor TFIID subunit 2"
					},
					{
						"name":"6506789 transcription initiation factor TFIID subunit 4 isoform X1\tK03129 TAF4; transcription initiation factor TFIID subunit 4"
					},
					{
						"name":"6493944 transcription initiation factor TFIID subunit 5\tK03130 TAF5; transcription initiation factor TFIID subunit 5"
					},
					{
						"name":"6500799 transcription initiation factor TFIID subunit 5\tK03130 TAF5; transcription initiation factor TFIID subunit 5"
					},
					{
						"name":"6506348 transcription initiation factor TFIID subunit 6\tK03131 TAF6; transcription initiation factor TFIID subunit 6"
					},
					{
						"name":"6500957 transcription initiation factor TFIID subunit 7\tK03132 TAF7; transcription initiation factor TFIID subunit 7"
					},
					{
						"name":"6502131 transcription initiation factor TFIID subunit 8\tK14649 TAF8; transcription initiation factor TFIID subunit 8"
					},
					{
						"name":"6496707 transcription initiation factor TFIID subunit 10b\tK03134 TAF10; transcription initiation factor TFIID subunit 10"
					},
					{
						"name":"6496728 transcription initiation factor TFIID subunit 10\tK03134 TAF10; transcription initiation factor TFIID subunit 10"
					},
					{
						"name":"6504555 transcription initiation factor TFIID subunit 11\tK03135 TAF11; transcription initiation factor TFIID subunit 11"
					},
					{
						"name":"6499421 transcription initiation factor TFIID subunit 12 isoform X2\tK03126 TAF12; transcription initiation factor TFIID subunit 12"
					},
					{
						"name":"6497273 transcription initiation factor TFIID subunit 13\tK03127 TAF13; transcription initiation factor TFIID subunit 13"
					}
					]
				},
				{
					"name":"TFIIE",
					"children":[
					{
						"name":"6507905 general transcription factor IIE subunit 1\tK03136 TFIIE1; transcription initiation factor TFIIE subunit alpha"
					},
					{
						"name":"6507686 general transcription factor IIE subunit 2\tK03137 TFIIE2; transcription initiation factor TFIIE subunit beta"
					}
					]
				},
				{
					"name":"TFIIF",
					"children":[
					{
						"name":"6501135 general transcription factor IIF subunit 1\tK03138 TFIIF1; transcription initiation factor TFIIF subunit alpha"
					},
					{
						"name":"6500221 general transcription factor IIF subunit 2\tK03139 TFIIF2; transcription initiation factor TFIIF subunit beta [EC:5.6.2.-]"
					}
					]
				},
				{
					"name":"TFIIH",
					"children":[
					{
						"name":"6496337 general transcription factor IIH subunit 1\tK03141 TFIIH1; transcription initiation factor TFIIH subunit 1"
					},
					{
						"name":"6493871 general transcription factor IIH subunit 2 isoform X1\tK03142 TFIIH2; transcription initiation factor TFIIH subunit 2"
					},
					{
						"name":"6497554 general transcription factor IIH subunit 3\tK03143 TFIIH3; transcription initiation factor TFIIH subunit 3"
					},
					{
						"name":"6493262 general transcription factor IIH subunit 4\tK03144 TFIIH4; transcription initiation factor TFIIH subunit 4"
					},
					{
						"name":"6493467 general transcription and DNA repair factor IIH helicase subunit XPB\tK10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]"
					},
					{
						"name":"6494799 general transcription and DNA repair factor IIH helicase subunit XPD\tK10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]"
					},
					{
						"name":"6498519 general transcription factor IIH subunit 5\tK10845 TTDA; TFIIH basal transcription factor complex TTD-A subunit"
					},
					{
						"name":"6503642 cyclin-dependent kinase 7\tK02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]"
					},
					{
						"name":"6493956 CDK-activating kinase assembly factor MAT1\tK10842 MNAT1; CDK-activating kinase assembly factor MAT1"
					},
					{
						"name":"6507797 cyclin-H\tK06634 CCNH; cyclin H"
					}
					]
				}
				]
			},
			{
				"name":"Mediator complex",
				"children":[
				{
					"name":"Head",
					"children":[
					{
						"name":"6505837 mediator of RNA polymerase II transcription subunit 6\tK15128 MED6; mediator of RNA polymerase II transcription subunit 6"
					},
					{
						"name":"6495518 mediator of RNA polymerase II transcription subunit 8\tK15129 MED8; mediator of RNA polymerase II transcription subunit 8"
					},
					{
						"name":"6506280 mediator of RNA polymerase II transcription subunit 11\tK15131 MED11; mediator of RNA polymerase II transcription subunit 11"
					},
					{
						"name":"6501283 mediator of RNA polymerase II transcription subunit 17\tK15133 MED17; mediator of RNA polymerase II transcription subunit 17"
					},
					{
						"name":"6503886 mediator of RNA polymerase II transcription subunit 18\tK15135 MED18; mediator of RNA polymerase II transcription subunit 18"
					},
					{
						"name":"6507856 mediator of RNA polymerase II transcription subunit 19\tK15137 MED19; mediator of RNA polymerase II transcription subunit 19"
					},
					{
						"name":"6505259 mediator of RNA polymerase II transcription subunit 20\tK13528 MED20; mediator of RNA polymerase II transcription subunit 20"
					},
					{
						"name":"6504782 mediator of RNA polymerase II transcription subunit 22\tK15139 MED22; mediator of RNA polymerase II transcription subunit 22"
					},
					{
						"name":"6499727 mediator of RNA polymerase II transcription subunit 28\tK15141 MED28; mediator of RNA polymerase II transcription subunit 28"
					},
					{
						"name":"6495249 mediator of RNA polymerase II transcription subunit 29\tK15142 MED29; mediator of RNA polymerase II transcription subunit 29"
					},
					{
						"name":"6492933 mediator of RNA polymerase II transcription subunit 30\tK15143 MED30; mediator of RNA polymerase II transcription subunit 30"
					}
					]
				},
				{
					"name":"Middle",
					"children":[
					{
						"name":"6506502 mediator of RNA polymerase II transcription subunit 4\tK15146 MED4; mediator of RNA polymerase II transcription subunit 4"
					},
					{
						"name":"6500222 mediator of RNA polymerase II transcription subunit 7\tK15148 MED7; mediator of RNA polymerase II transcription subunit 7"
					},
					{
						"name":"6494996 mediator of RNA polymerase II transcription subunit 9\tK15149 MED9; mediator of RNA polymerase II transcription subunit 9"
					},
					{
						"name":"6494997 protein NCBP2AS2 homolog\tK15149 MED9; mediator of RNA polymerase II transcription subunit 9"
					},
					{
						"name":"6506795 mediator of RNA polymerase II transcription subunit 10\tK15151 MED10; mediator of RNA polymerase II transcription subunit 10"
					},
					{
						"name":"26515043 mediator of RNA polymerase II transcription subunit 21\tK15152 MED21; mediator of RNA polymerase II transcription subunit 21"
					},
					{
						"name":"6499458 mediator of RNA polymerase II transcription subunit 31 isoform X1\tK15153 MED31; mediator of RNA polymerase II transcription subunit 31"
					}
					]
				},
				{
					"name":"Tail",
					"children":[
					{
						"name":"6507389 mediator of RNA polymerase II transcription subunit 14\tK15156 MED14; mediator of RNA polymerase II transcription subunit 14"
					},
					{
						"name":"6503360 mediator of RNA polymerase II transcription subunit 15\tK15157 MED15; mediator of RNA polymerase II transcription subunit 15"
					},
					{
						"name":"6494518 mediator of RNA polymerase II transcription subunit 16\tK15159 MED16; mediator of RNA polymerase II transcription subunit 16"
					}
					]
				},
				{
					"name":"CDK-module",
					"children":[
					{
						"name":"6493101 cyclin-dependent kinase 8\tK02208 CDK8_11; cyclin-dependent kinase 8\/11 [EC:2.7.11.22 2.7.11.23]"
					},
					{
						"name":"6500903 cyclin-C\tK15161 CCNC; cyclin-C"
					},
					{
						"name":"6506238 mediator of RNA polymerase II transcription subunit 12 isoform X2\tK15162 MED12; mediator of RNA polymerase II transcription subunit 12"
					},
					{
						"name":"6493066 mediator of RNA polymerase II transcription subunit 13 isoform X1\tK15164 MED13; mediator of RNA polymerase II transcription subunit 13"
					}
					]
				},
				{
					"name":"Other mediators",
					"children":[
					{
						"name":"6496392 mediator of RNA polymerase II transcription subunit 23\tK15166 MED23; mediator of RNA polymerase II transcription subunit 23"
					},
					{
						"name":"6507727 mediator of RNA polymerase II transcription subunit 24\tK15167 MED24; mediator of RNA polymerase II transcription subunit 24"
					},
					{
						"name":"6498914 mediator of RNA polymerase II transcription subunit 25\tK15168 MED25; mediator of RNA polymerase II transcription subunit 25"
					},
					{
						"name":"6500362 mediator of RNA polymerase II transcription subunit 27\tK15170 MED27; mediator of RNA polymerase II transcription subunit 27"
					}
					]
				}
				]
			},
			{
				"name":"Coactivators",
				"children":[
				{
					"name":"SAGA\/TFTC\/STAGA complex",
					"children":[
					{
						"name":"6506644 histone acetyltransferase KAT2A\tK06062 PCAF; histone acetyltransferase [EC:2.3.1.48]"
					},
					{
						"name":"6500013 transcription initiation protein SPT3 homolog\tK11313 SUPT3H; transcription initiation protein SPT3"
					},
					{
						"name":"6505796 transcriptional adapter 2A isoform X2\tK11314 TADA2A; transcriptional adapter 2-alpha"
					},
					{
						"name":"6498965 transcriptional adapter 2B isoform X1\tK15127 TADA2B; transcriptional adapter 2-beta"
					},
					{
						"name":"6502127 transcriptional adapter 3\tK11315 TADA3; transcriptional adapter 3"
					},
					{
						"name":"6497951 transcriptional adapter 1\tK11317 TADA1; transcriptional adapter 1"
					},
					{
						"name":"6506493 transcription initiation factor TFIID subunit 2\tK03128 TAF2; transcription initiation factor TFIID subunit 2"
					},
					{
						"name":"6506789 transcription initiation factor TFIID subunit 4 isoform X1\tK03129 TAF4; transcription initiation factor TFIID subunit 4"
					},
					{
						"name":"6493944 transcription initiation factor TFIID subunit 5\tK03130 TAF5; transcription initiation factor TFIID subunit 5"
					},
					{
						"name":"6500799 transcription initiation factor TFIID subunit 5\tK03130 TAF5; transcription initiation factor TFIID subunit 5"
					},
					{
						"name":"6506348 transcription initiation factor TFIID subunit 6\tK03131 TAF6; transcription initiation factor TFIID subunit 6"
					},
					{
						"name":"6500957 transcription initiation factor TFIID subunit 7\tK03132 TAF7; transcription initiation factor TFIID subunit 7"
					},
					{
						"name":"6496707 transcription initiation factor TFIID subunit 10b\tK03134 TAF10; transcription initiation factor TFIID subunit 10"
					},
					{
						"name":"6496728 transcription initiation factor TFIID subunit 10\tK03134 TAF10; transcription initiation factor TFIID subunit 10"
					},
					{
						"name":"6499421 transcription initiation factor TFIID subunit 12 isoform X2\tK03126 TAF12; transcription initiation factor TFIID subunit 12"
					},
					{
						"name":"6493677 SAGA-associated factor 11 homolog\tK11363 ATXN7L; SAGA-associated factor 11"
					},
					{
						"name":"6494965 SAGA-associated factor 29\tK11364 SGF29; SAGA-associated factor 29"
					},
					{
						"name":"6503798 uncharacterized protein LOC6503798\tK11316 SUPT7L; STAGA complex 65 subunit gamma"
					},
					{
						"name":"6497164 chromodomain-helicase-DNA-binding protein 1 isoform X3\tK11367 CHD1; chromodomain-helicase-DNA-binding protein 1 [EC:5.6.2.-]"
					},
					{
						"name":"6503072 enhancer of yellow 2 transcription factor isoform X1\tK11368 ENY2; enhancer of yellow 2 transcription factor"
					},
					{
						"name":"6493680 ubiquitin carboxyl-terminal hydrolase nonstop\tK11366 USP22_27_51; ubiquitin carboxyl-terminal hydrolase 22\/27\/51 [EC:3.4.19.12]"
					},
					{
						"name":"6506698 splicing factor 3B subunit 3 isoform X1\tK12830 SF3B3; splicing factor 3B subunit 3"
					}
					]
				},
				{
					"name":"BAF\/PBAF complex",
					"children":[
					{
						"name":"6493236 ATP-dependent helicase brm isoform X2\tK11647 SMARCA2_4; SWI\/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2\/4 [EC:5.6.2.-]"
					},
					{
						"name":"6500039 SWI\/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1\tK11648 SMARCB1; SWI\/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1"
					},
					{
						"name":"6499261 SWI\/SNF complex subunit SMARCC1 isoform X1\tK11649 SMARCC; SWI\/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C"
					},
					{
						"name":"6503655 brahma-associated protein of 60 kDa\tK11650 SMARCD; SWI\/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D"
					},
					{
						"name":"6501893 basic proline-rich protein\tK11651 SMARCE1; SWI\/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1"
					},
					{
						"name":"6493807 actin, larval muscle\tK05692 ACTB_G1; actin beta\/gamma 1"
					},
					{
						"name":"6495063 actin-57B\tK05692 ACTB_G1; actin beta\/gamma 1"
					},
					{
						"name":"6496662 actin-42A\tK05692 ACTB_G1; actin beta\/gamma 1"
					},
					{
						"name":"6500386 actin-87E\tK05692 ACTB_G1; actin beta\/gamma 1"
					},
					{
						"name":"6501076 actin, indirect flight muscle\tK05692 ACTB_G1; actin beta\/gamma 1"
					},
					{
						"name":"6504746 actin-5C\tK05692 ACTB_G1; actin beta\/gamma 1"
					},
					{
						"name":"6494647 actin-like protein 6B\tK11652 ACTL6B; actin-like protein 6B"
					},
					{
						"name":"6505787 trithorax group protein osa isoform X1\tK11653 ARID1; AT-rich interactive domain-containing protein 1"
					},
					{
						"name":"6493922 SWI\/SNF nucleosome remodeling complex component\tK11765 ARID2; AT-rich interactive domain-containing protein 2"
					},
					{
						"name":"6505826 protein polybromo-1\tK11757 PBRM1; protein polybromo-1"
					}
					]
				},
				{
					"name":"SWI\/SNF complex",
					"children":[
					{
						"name":"6500039 SWI\/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1\tK11648 SMARCB1; SWI\/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1"
					}
					]
				},
				{
					"name":"RSC complex"
				},
				{
					"name":"Others",
					"children":[
					{
						"name":"6498085 RNA polymerase II transcriptional coactivator\tK25815 SUB1; activated RNA polymerase II transcriptional coactivator p15"
					}
					]
				}
				]
			},
			{
				"name":"Other transcription-related factors",
				"children":[
				{
					"name":"Transcription elongation factors",
					"children":[
					{
						"name":"6498369 transcription elongation factor S-II\tK03145 TFIIS; transcription elongation factor S-II"
					},
					{
						"name":"6496241 transcription elongation factor SPT4\tK15171 SUPT4H1; transcription elongation factor SPT4"
					},
					{
						"name":"6495192 transcription elongation factor SPT5\tK15172 SUPT5H; transcription elongation factor SPT5"
					},
					{
						"name":"6503095 transcription elongation factor SPT6\tK11292 SUPT6H; transcription elongation factor SPT6"
					}
					]
				},
				{
					"name":"Transcription termination factor",
					"children":[
					{
						"name":"6494940 uncharacterized protein LOC6494940 isoform X5\tK14400 PCF11; pre-mRNA cleavage complex 2 protein Pcf11"
					},
					{
						"name":"6494213 cleavage and polyadenylation specificity factor subunit 1\tK14401 CPSF1; cleavage and polyadenylation specificity factor subunit 1"
					},
					{
						"name":"6500879 cleavage and polyadenylation specificity factor 73\tK14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]"
					},
					{
						"name":"26514018 cleavage and polyadenylation specificity factor subunit 4\tK14404 CPSF4; cleavage and polyadenylation specificity factor subunit 4"
					},
					{
						"name":"6496057 serine\/threonine-protein phosphatase PP-Y\tK06269 PPP1C; serine\/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"6499833 serine\/threonine-protein phosphatase alpha-2 isoform\tK06269 PPP1C; serine\/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"6502328 serine\/threonine-protein phosphatase alpha-1 isoform\tK06269 PPP1C; serine\/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"6502914 serine\/threonine-protein phosphatase PP1\tK06269 PPP1C; serine\/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"6503446 serine\/threonine-protein phosphatase alpha-1 isoform\tK06269 PPP1C; serine\/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"6503731 serine\/threonine-protein phosphatase alpha-3 isoform\tK06269 PPP1C; serine\/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"6501421 symplekin\tK06100 SYMPK; symplekin"
					},
					{
						"name":"6503127 RNA polymerase II subunit A C-terminal domain phosphatase SSU72\tK15544 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 [EC:3.1.3.16]"
					},
					{
						"name":"6498242 5'-3' exoribonuclease 2 homolog\tK12619 XRN2; 5'-3' exoribonuclease 2 [EC:3.1.13.-]"
					},
					{
						"name":"6507556 regulation of nuclear pre-mRNA domain-containing protein 1A\tK15559 RTT103; regulator of Ty1 transposition protein 103"
					},
					{
						"name":"6502028 protein no-on-transient A isoform X2\tK13219 SFPQ; splicing factor, proline- and glutamine-rich"
					},
					{
						"name":"6493350 probable helicase senataxin\tK10706 SETX; ATP-dependent RNA\/DNA helicase, senataxin [EC:5.6.2.5 5.6.2.3]"
					},
					{
						"name":"6505205 putative peptidyl-prolyl cis-trans isomerase dodo\tK09578 PIN1; peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 [EC:5.2.1.8]"
					}
					]
				},
				{
					"name":"PAF1 complex",
					"children":[
					{
						"name":"6501676 RNA polymerase II-associated factor 1 homolog\tK15174 PAF1; RNA polymerase II-associated factor 1"
					},
					{
						"name":"6499374 parafibromin\tK15175 CDC73; parafibromin"
					},
					{
						"name":"6507084 RNA polymerase-associated protein CTR9 homolog\tK15176 CTR9; RNA polymerase-associated protein CTR9"
					},
					{
						"name":"6494746 RNA polymerase-associated protein Rtf1\tK15178 RTF1; RNA polymerase-associated protein RTF1"
					}
					]
				},
				{
					"name":"NELF complex",
					"children":[
					{
						"name":"6501714 negative elongation factor A\tK15179 WHSC2; negative elongation factor A"
					},
					{
						"name":"6503808 negative elongation factor B\tK15180 COBRA1; negative elongation factor B"
					},
					{
						"name":"6502324 negative elongation factor D\tK15181 TH1L; negative elongation factor C\/D"
					},
					{
						"name":"6493031 negative elongation factor E\tK15182 RDBP; negative elongation factor E"
					}
					]
				},
				{
					"name":"Super elongation complex (SEC)",
					"children":[
					{
						"name":"6495851 cyclin-dependent kinase 9\tK02211 CDK9; cyclin-dependent kinase 9 [EC:2.7.11.22 2.7.11.23]"
					}
					]
				},
				{
					"name":"Little elongation complex (LEC)"
				},
				{
					"name":"Brd4\/P-TEFb complex",
					"children":[
					{
						"name":"6495851 cyclin-dependent kinase 9\tK02211 CDK9; cyclin-dependent kinase 9 [EC:2.7.11.22 2.7.11.23]"
					}
					]
				},
				{
					"name":"BUR kinase complex"
				},
				{
					"name":"CTDK-I complex"
				},
				{
					"name":"7SK RNP complex",
					"children":[
					{
						"name":"6500235 protein HEXIM1\tK15189 HEXIM1_2; protein HEXIM1\/2"
					},
					{
						"name":"6493917 probable RNA methyltransferase bin3\tK15190 MEPCE; 7SK snRNA methylphosphate capping enzyme [EC:2.1.1.-]"
					},
					{
						"name":"6495851 cyclin-dependent kinase 9\tK02211 CDK9; cyclin-dependent kinase 9 [EC:2.7.11.22 2.7.11.23]"
					}
					]
				},
				{
					"name":"DBIRD complex"
				},
				{
					"name":"Others",
					"children":[
					{
						"name":"6501327 TATA-binding protein-associated factor 172\tK15192 BTAF1; TATA-binding protein-associated factor [EC:5.6.2.-]"
					},
					{
						"name":"6497715 protein Dr1\tK21751 DR1; down-regulator of transcription 1"
					},
					{
						"name":"6496100 dr1-associated corepressor\tK21752 DRAP1; Dr1-associated corepressor"
					},
					{
						"name":"6494106 RNA polymerase II subunit A C-terminal domain phosphatase\tK15732 CTDP1; RNA polymerase II subunit A C-terminal domain phosphatase [EC:3.1.3.16]"
					},
					{
						"name":"6493234 carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1\tK15731 CTDSP; carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase [EC:3.1.3.16]"
					},
					{
						"name":"6498048 putative RNA polymerase II subunit B1 CTD phosphatase RPAP2 homolog\tK20827 RPAP2; RNA polymerase II-associated protein 2 [EC:3.1.3.16]"
					},
					{
						"name":"6498195 cyclin-K\tK23326 CCNK; cyclin K"
					},
					{
						"name":"6493822 GPN-loop GTPase 2\tK24104 GPN; GPN-loop GTPase"
					},
					{
						"name":"6500439 GPN-loop GTPase 3\tK24104 GPN; GPN-loop GTPase"
					},
					{
						"name":"6504717 GPN-loop GTPase 1\tK24104 GPN; GPN-loop GTPase"
					},
					{
						"name":"6498281 probable RNA polymerase II nuclear localization protein SLC7A6OS isoform X1\tK28237 SLC7A6OS; RNA polymerase II nuclear localization protein"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"RNA polymerase III system",
			"children":[
			{
				"name":"RNA polymerase III",
				"children":[
				{
					"name":"Core subunits",
					"children":[
					{
						"name":"6497685 DNA-directed RNA polymerase III subunit RPC1\tK03018 RPC1; DNA-directed RNA polymerase III subunit RPC1 [EC:2.7.7.6]"
					},
					{
						"name":"6495138 DNA-directed RNA polymerase III subunit RPC2\tK03021 RPC2; DNA-directed RNA polymerase III subunit RPC2 [EC:2.7.7.6]"
					},
					{
						"name":"6504212 DNA-directed RNA polymerases I and III subunit RPAC1\tK03027 RPAC1; DNA-directed RNA polymerases I and III subunit RPAC1"
					},
					{
						"name":"6498018 probable DNA-directed RNA polymerases I and III subunit RPAC2\tK03020 RPAC2; DNA-directed RNA polymerases I and III subunit RPAC2"
					}
					]
				},
				{
					"name":"Pol III specific subunits",
					"children":[
					{
						"name":"6500745 DNA-directed RNA polymerase III subunit RPC3\tK03023 RPC3; DNA-directed RNA polymerase III subunit RPC3"
					},
					{
						"name":"6506926 DNA-directed RNA polymerase III subunit RPC5\tK14721 RPC5; DNA-directed RNA polymerase III subunit RPC5"
					},
					{
						"name":"6499728 probable DNA-directed RNA polymerase III subunit RPC6\tK03025 RPC6; DNA-directed RNA polymerase III subunit RPC6"
					},
					{
						"name":"6506944 DNA-directed RNA polymerase III subunit RPC7-like\tK03024 RPC7; DNA-directed RNA polymerase III subunit RPC7"
					},
					{
						"name":"6507904 DNA-directed RNA polymerase III subunit RPC8\tK03022 RPC8; DNA-directed RNA polymerase III subunit RPC8"
					},
					{
						"name":"6496751 DNA-directed RNA polymerase III subunit RPC9\tK25304 RPC9; DNA-directed RNA polymerase III subunit RPC9"
					},
					{
						"name":"6495599 DNA-directed RNA polymerase III subunit RPC10\tK03019 RPC11; DNA-directed RNA polymerase III subunit RPC11"
					}
					]
				},
				{
					"name":"Pol I, II, III common subunits",
					"children":[
					{
						"name":"6495295 DNA-directed RNA polymerases I, II, and III subunit RPABC1\tK03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1"
					},
					{
						"name":"6500033 DNA-directed RNA polymerases I, II, and III subunit RPABC2\tK03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2"
					},
					{
						"name":"6507791 DNA-directed RNA polymerases I, II, and III subunit RPABC3\tK03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3"
					},
					{
						"name":"6495477 DNA-directed RNA polymerases I, II, and III subunit RPABC4\tK03009 RPABC4; DNA-directed RNA polymerases I, II, and III subunit RPABC4"
					},
					{
						"name":"6500009 DNA-directed RNA polymerases I, II, and III subunit RPABC5\tK03007 RPABC5; DNA-directed RNA polymerases I, II, and III subunit RPABC5"
					}
					]
				}
				]
			},
			{
				"name":"Basal transcription factors",
				"children":[
				{
					"name":"TFIIIA"
				},
				{
					"name":"TFIIIB",
					"children":[
					{
						"name":"6494491 TATA-box-binding protein\tK03120 TBP; transcription initiation factor TFIID TATA-box-binding protein"
					},
					{
						"name":"6497577 TBP-related factor\tK03120 TBP; transcription initiation factor TFIID TATA-box-binding protein"
					},
					{
						"name":"6499678 transcription factor IIIB 90 kDa subunit\tK15196 BRF1; transcription factor IIIB 90 kDa subunit"
					},
					{
						"name":"6504338 transcription factor TFIIIB component B''\tK15198 BDP1; transcription factor TFIIIB component B''"
					}
					]
				},
				{
					"name":"TFIIIC",
					"children":[
					{
						"name":"6496269 general transcription factor 3C polypeptide 3\tK15201 GTP3C3; general transcription factor 3C polypeptide 3 (transcription factor C subunit 4)"
					},
					{
						"name":"6497525 general transcription factor 3C polypeptide 5\tK15202 GTF3C5; general transcription factor 3C polypeptide 5 (transcription factor C subunit 1)"
					}
					]
				},
				{
					"name":"TFIIIC, fungi type",
					"children":[
					{
						"name":"6497525 general transcription factor 3C polypeptide 5\tK15202 GTF3C5; general transcription factor 3C polypeptide 5 (transcription factor C subunit 1)"
					},
					{
						"name":"6496269 general transcription factor 3C polypeptide 3\tK15201 GTP3C3; general transcription factor 3C polypeptide 3 (transcription factor C subunit 4)"
					}
					]
				}
				]
			},
			{
				"name":"Other transcription-related factors",
				"children":[
				{
					"name":"snRNA-activating protein complex (SNAPc)"
				},
				{
					"name":"Octamer transcription factors",
					"children":[
					{
						"name":"6497028 protein nubbin isoform X2\tK09364 POU2F; POU domain transcription factor, class 2"
					}
					]
				},
				{
					"name":"Others",
					"children":[
					{
						"name":"6496778 repressor of RNA polymerase III transcription MAF1 homolog isoform X2\tK25817 MAF1; repressor of RNA polymerase III transcription MAF1"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"RNA polymerase I system",
			"children":[
			{
				"name":"RNA polymerase I",
				"children":[
				{
					"name":"Core subunits",
					"children":[
					{
						"name":"6496368 DNA-directed RNA polymerase I subunit RPA1\tK02999 RPA1; DNA-directed RNA polymerase I subunit RPA1 [EC:2.7.7.6]"
					},
					{
						"name":"6503344 DNA-directed RNA polymerase I subunit RPA2\tK03002 RPA2; DNA-directed RNA polymerase I subunit RPA2 [EC:2.7.7.6]"
					},
					{
						"name":"6504212 DNA-directed RNA polymerases I and III subunit RPAC1\tK03027 RPAC1; DNA-directed RNA polymerases I and III subunit RPAC1"
					},
					{
						"name":"6498018 probable DNA-directed RNA polymerases I and III subunit RPAC2\tK03020 RPAC2; DNA-directed RNA polymerases I and III subunit RPAC2"
					}
					]
				},
				{
					"name":"Pol I specific subunits",
					"children":[
					{
						"name":"6500249 DNA-directed RNA polymerase I subunit RPA12\tK03000 RPA12; DNA-directed RNA polymerase I subunit RPA12"
					}
					]
				},
				{
					"name":"Pol I, II, III common subunits",
					"children":[
					{
						"name":"6495295 DNA-directed RNA polymerases I, II, and III subunit RPABC1\tK03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1"
					},
					{
						"name":"6500033 DNA-directed RNA polymerases I, II, and III subunit RPABC2\tK03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2"
					},
					{
						"name":"6507791 DNA-directed RNA polymerases I, II, and III subunit RPABC3\tK03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3"
					},
					{
						"name":"6495477 DNA-directed RNA polymerases I, II, and III subunit RPABC4\tK03009 RPABC4; DNA-directed RNA polymerases I, II, and III subunit RPABC4"
					},
					{
						"name":"6500009 DNA-directed RNA polymerases I, II, and III subunit RPABC5\tK03007 RPABC5; DNA-directed RNA polymerases I, II, and III subunit RPABC5"
					}
					]
				}
				]
			},
			{
				"name":"Basal transcription factors",
				"children":[
				{
					"name":"SL1\/TIF-1B",
					"children":[
					{
						"name":"6494491 TATA-box-binding protein\tK03120 TBP; transcription initiation factor TFIID TATA-box-binding protein"
					},
					{
						"name":"6497577 TBP-related factor\tK03120 TBP; transcription initiation factor TFIID TATA-box-binding protein"
					}
					]
				}
				]
			},
			{
				"name":"Other transcription-related factors",
				"children":[
				{
					"name":"UBF"
				},
				{
					"name":"Transcription initiation factors",
					"children":[
					{
						"name":"6505408 RNA polymerase I-specific transcription initiation factor RRN3 isoform X1\tK15216 RRN3; RNA polymerase I-specific transcription initiation factor RRN3"
					},
					{
						"name":"6506880 upstream activation factor subunit spp27\tK15223 UAF30; upstream activation factor subunit UAF30"
					}
					]
				},
				{
					"name":"Transcription elongation factors",
					"children":[
					{
						"name":"6496241 transcription elongation factor SPT4\tK15171 SUPT4H1; transcription elongation factor SPT4"
					},
					{
						"name":"6495192 transcription elongation factor SPT5\tK15172 SUPT5H; transcription elongation factor SPT5"
					}
					]
				},
				{
					"name":"NoRC (nucleolar remodeling complex)",
					"children":[
					{
						"name":"6496242 chromatin-remodeling complex ATPase chain Iswi\tK11654 SMARCA5; SWI\/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 [EC:5.6.2.-]"
					}
					]
				},
				{
					"name":"CTDK-I complex"
				},
				{
					"name":"Transcription termination factors"
				},
				{
					"name":"Others",
					"children":[
					{
						"name":"6493799 nucleolar protein dao-5 isoform X3\tK25818 NOLC1; nucleolar and coiled-body phosphoprotein 1"
					}
					]
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic type",
		"children":[
		{
			"name":"Bacterial type",
			"children":[
			{
				"name":"RNA polymerase",
				"children":[
				{
					"name":"Core subunits"
				},
				{
					"name":"Sigma factors"
				}
				]
			},
			{
				"name":"Other transcription-related factors",
				"children":[
				{
					"name":"RNA polymerase-associated proteins"
				},
				{
					"name":"Transcription elongation factors"
				},
				{
					"name":"Transcription termination factor"
				}
				]
			}
			]
		},
		{
			"name":"Archaeal type",
			"children":[
			{
				"name":"RNA polymerase",
				"children":[
				{
					"name":"Core subunits"
				}
				]
			},
			{
				"name":"Basal transcription factors",
				"children":[
				{
					"name":"TFB",
					"children":[
					{
						"name":"6498595 transcription initiation factor IIB\tK03124 TFIIB; transcription initiation factor TFIIB"
					}
					]
				},
				{
					"name":"TFE",
					"children":[
					{
						"name":"6507905 general transcription factor IIE subunit 1\tK03136 TFIIE1; transcription initiation factor TFIIE subunit alpha"
					}
					]
				},
				{
					"name":"TFS"
				}
				]
			}
			]
		}
		]
	}
	]
}