{
	"name":"dar03000",
	"children":[
	{
		"name":"Eukaryotic type",
		"children":[
		{
			"name":"Basic leucine zipper (bZIP)",
			"children":[
			{
				"name":"AP-1(-like) components, Jun"
			},
			{
				"name":"AP-1(-like) components, Fos"
			},
			{
				"name":"AP-1(-like) components, Maf"
			},
			{
				"name":"AP-1(-like) components, NF-E2"
			},
			{
				"name":"AP-1(-like) components, Fungal regulators"
			},
			{
				"name":"AP-1(-like) components, CRE-BP\/ATF"
			},
			{
				"name":"CREB"
			},
			{
				"name":"C\/EBP-like factors"
			},
			{
				"name":"bZIP\/PAR"
			},
			{
				"name":"Plant bZIP factors"
			},
			{
				"name":"ZIP only"
			}
			]
		},
		{
			"name":"Basic helix-loop-helix (bHLH)",
			"children":[
			{
				"name":"Ubiquitous (class A) factors"
			},
			{
				"name":"Myogenic transcription factors"
			},
			{
				"name":"Achaete-Scute"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, Lymphoid factors"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, Mesodermal Twist-like factors"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, HEN"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, Mesp"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, Atonal"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, Pancreatic factors"
			},
			{
				"name":"Hairy, Hairy\/E(SPL)"
			},
			{
				"name":"Hairy, Fungal regulators"
			},
			{
				"name":"Factors with PAS domain"
			},
			{
				"name":"Yabby"
			},
			{
				"name":"INO"
			},
			{
				"name":"HLH domain only"
			}
			]
		},
		{
			"name":"Basic helix-loop-helix\/leucine zipper (bHLH-ZIP)",
			"children":[
			{
				"name":"Ubiquitous bHLH-ZIP factors"
			},
			{
				"name":"Cell cycle controlling factors, Myc"
			},
			{
				"name":"Cell cycle controlling factors, Mad\/Max"
			},
			{
				"name":"Other bHLH-ZIP factors"
			}
			]
		},
		{
			"name":"Other basic domains",
			"children":[
			{
				"name":"NF-1"
			},
			{
				"name":"RF-X"
			},
			{
				"name":"AP-2 (bHSH)"
			}
			]
		},
		{
			"name":"Zinc finger",
			"children":[
			{
				"name":"Cys4 thyroid hormone receptor-like"
			},
			{
				"name":"Cys4 hepatocyte nuclear factor 4-like"
			},
			{
				"name":"Cys4 estrogen receptor-like"
			},
			{
				"name":"Cys4 nerve growth factor IB-like"
			},
			{
				"name":"Cys4 Fushi tarazu-F1-like"
			},
			{
				"name":"Cys4 germ cell nuclear factor"
			},
			{
				"name":"Cys4 Knirps\/DAX1-like"
			},
			{
				"name":"Cys4 GATA-factors"
			},
			{
				"name":"Cys2His2 SP\/KLF family and related proteins"
			},
			{
				"name":"Cys2His2 GLI-like"
			},
			{
				"name":"Cys2His2 Snail"
			},
			{
				"name":"Cys2His2 BTB-ZF factors"
			},
			{
				"name":"Cys2His2 BED"
			},
			{
				"name":"Cys2His2 PRDM"
			},
			{
				"name":"Cys2His2 metabolic regulators in fungi"
			},
			{
				"name":"Cys2His2 others"
			},
			{
				"name":"Cys2HisCys zinc factors"
			},
			{
				"name":"Cys3His zinc factors"
			},
			{
				"name":"Cys2CysHis zinc factors"
			},
			{
				"name":"CXXC CpG-binding proteins",
				"children":[
				{
					"name":"Daro_3525 C-5 cytosine-specific DNA methylase\tK00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]"
				}
				]
			},
			{
				"name":"Cys6 metabolic regulators in fungi"
			},
			{
				"name":"Other zinc fingers"
			}
			]
		},
		{
			"name":"Helix-turn-helix",
			"children":[
			{
				"name":"Homeo domain ANTP: HOXL"
			},
			{
				"name":"Homeo domain ANTP: NKL"
			},
			{
				"name":"Homeo domain Paired-related"
			},
			{
				"name":"Homeo domain LIM"
			},
			{
				"name":"Homeo domain POU"
			},
			{
				"name":"Homeo domain SINE"
			},
			{
				"name":"Homeo domain ZF"
			},
			{
				"name":"Homeo domain CUT"
			},
			{
				"name":"Homeo domain PROS"
			},
			{
				"name":"Homeo domain TALE"
			},
			{
				"name":"Homeo domain other"
			},
			{
				"name":"Fork head\/winged helix developmental regulators"
			},
			{
				"name":"Fork head\/winged helix tissue-specific regulators"
			},
			{
				"name":"Fork head\/winged helix cell cycle-controlling factors, E2F"
			},
			{
				"name":"Fork head\/winged helix cell cycle-controlling factors, DP"
			},
			{
				"name":"Fork head\/winged helix other regulators"
			},
			{
				"name":"Stork head\/winged helix factors"
			},
			{
				"name":"Heat shock factors"
			},
			{
				"name":"Tryptophan clusters Myb, Myb-factors"
			},
			{
				"name":"Tryptophan clusters Myb, Myb-like factors"
			},
			{
				"name":"Tryptophan clusters Ets-type"
			},
			{
				"name":"Tryptophan clusters interferon-regulating factors"
			},
			{
				"name":"TEA domain"
			},
			{
				"name":"ARID"
			}
			]
		},
		{
			"name":"beta-Scaffold factors with minor groove contacts",
			"children":[
			{
				"name":"RHR (Rel homology region) Rel\/Ankyrin"
			},
			{
				"name":"RHR (Rel homology region) Ankyrin only"
			},
			{
				"name":"RHR (Rel homology region) NF-AT"
			},
			{
				"name":"STAT"
			},
			{
				"name":"p53"
			},
			{
				"name":"MADS-box regulators of differentiation, MEF-2"
			},
			{
				"name":"MADS-box regulators of differentiation, Homeotic genes"
			},
			{
				"name":"MADS-box regulators of differentiation, Yeast regulators"
			},
			{
				"name":"MADS-box responders to external signals"
			},
			{
				"name":"SAND domain-containing proteins"
			},
			{
				"name":"TATA-binding proteins"
			},
			{
				"name":"HMG SOX"
			},
			{
				"name":"HMG TCF-1"
			},
			{
				"name":"HMG TOX"
			},
			{
				"name":"HMG2-related"
			},
			{
				"name":"UBF"
			},
			{
				"name":"Other HMG box factors"
			},
			{
				"name":"Heteromeric CCAAT factors"
			},
			{
				"name":"Grainyhead"
			},
			{
				"name":"Cold-shock domain factors, DbpA-like"
			},
			{
				"name":"Cold-shock domain factors, YB-1\/DbpB-like"
			},
			{
				"name":"Cold-shock domain factors, FRG Y2-like"
			},
			{
				"name":"Runt"
			},
			{
				"name":"MYRF"
			}
			]
		},
		{
			"name":"Other transcription factors",
			"children":[
			{
				"name":"HMGI(Y)"
			},
			{
				"name":"NUPR"
			},
			{
				"name":"Pocket domain Rb"
			},
			{
				"name":"Pocket domain CBP"
			},
			{
				"name":"T-box"
			},
			{
				"name":"DMRT"
			},
			{
				"name":"LRRFIP"
			},
			{
				"name":"TCP"
			},
			{
				"name":"AP2\/ERF"
			},
			{
				"name":"WRKY"
			},
			{
				"name":"LOB"
			},
			{
				"name":"GRAS"
			},
			{
				"name":"NAC"
			},
			{
				"name":"Copper-fist proteins fungal regulators"
			},
			{
				"name":"Others"
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic type",
		"children":[
		{
			"name":"Helix-turn-helix",
			"children":[
			{
				"name":"AraC family"
			},
			{
				"name":"LysR family",
				"children":[
				{
					"name":"Daro_2809 transcriptional regulator, LysR family\tK03566 gcvA; LysR family transcriptional regulator, glycine cleavage system transcriptional activator"
				},
				{
					"name":"Daro_3580 transcriptional regulator, LysR family\tK03566 gcvA; LysR family transcriptional regulator, glycine cleavage system transcriptional activator"
				},
				{
					"name":"Daro_4077 transcriptional regulator, LysR family\tK03566 gcvA; LysR family transcriptional regulator, glycine cleavage system transcriptional activator"
				},
				{
					"name":"Daro_0292 transcriptional regulator, LysR family\tK03717 nhaR; LysR family transcriptional regulator, transcriptional activator of nhaA"
				},
				{
					"name":"Daro_0017 transcriptional regulator, LysR family\tK04761 oxyR; LysR family transcriptional regulator, hydrogen peroxide-inducible genes activator"
				},
				{
					"name":"Daro_2910 transcriptional regulator, LysR family\tK13634 cysB; LysR family transcriptional regulator, cys regulon transcriptional activator"
				},
				{
					"name":"Daro_2129 regulatory protein, LysR:LysR, substrate-binding protein\tK13635 cbl; LysR family transcriptional regulator, cys regulon transcriptional activator"
				},
				{
					"name":"Daro_1136 transcriptional regulator, LysR family\tK16135 dmlR; LysR family transcriptional regulator, transcriptional activator for dmlA"
				},
				{
					"name":"Daro_3831 transcriptional regulator, LysR family\tK18900 bpeT; LysR family transcriptional regulator, regulator for bpeEF and oprC"
				},
				{
					"name":"Daro_0476 transcriptional regulator, LysR family\tK19338 nac; LysR family transcriptional regulator, nitrogen assimilation regulatory protein"
				},
				{
					"name":"Daro_3638 transcriptional regulator, LysR family\tK21703 cbbR; LysR family transcriptional regulator, low CO2-responsive transcriptional regulator"
				}
				]
			},
			{
				"name":"DeoR family"
			},
			{
				"name":"LacI family"
			},
			{
				"name":"GntR family",
				"children":[
				{
					"name":"Daro_2866 transcriptional regulator, GntR family\tK03710 K03710; GntR family transcriptional regulator"
				},
				{
					"name":"Daro_1767 transcriptional regulator, GntR family\tK05799 pdhR; GntR family transcriptional regulator, transcriptional repressor for pyruvate dehydrogenase complex"
				},
				{
					"name":"Daro_3790 transcriptional regulator, GntR family\tK15735 csiR; GntR family transcriptional regulator, carbon starvation induced regulator"
				}
				]
			},
			{
				"name":"TetR\/AcrR family",
				"children":[
				{
					"name":"Daro_2159 transcriptional regulator, TetR family\tK03577 acrR; TetR\/AcrR family transcriptional regulator, acrAB operon repressor"
				},
				{
					"name":"Daro_0627 cell division inhibitor SlmA\tK05501 slmA; TetR\/AcrR family transcriptional regulator"
				},
				{
					"name":"Daro_1100 transcriptional regulator, TetR family\tK16137 nemR; TetR\/AcrR family transcriptional regulator, transcriptional repressor for nem operon"
				},
				{
					"name":"Daro_1527 transcriptional regulator, TetR family\tK16137 nemR; TetR\/AcrR family transcriptional regulator, transcriptional repressor for nem operon"
				}
				]
			},
			{
				"name":"Lrp\/AsnC family",
				"children":[
				{
					"name":"Daro_0512 transcriptional regulator, AsnC family\tK03719 lrp; Lrp\/AsnC family transcriptional regulator, leucine-responsive regulatory protein"
				}
				]
			},
			{
				"name":"LuxR family"
			},
			{
				"name":"MarR family",
				"children":[
				{
					"name":"Daro_2110 regulatory protein, MarR\tK23775 ohrR; MarR family transcriptional regulator, organic hydroperoxide resistance regulator"
				}
				]
			},
			{
				"name":"MerR family",
				"children":[
				{
					"name":"Daro_0487 regulatory protein, MerR\tK22491 litR; MerR family transcriptional regulator, light-induced transcriptional regulator"
				}
				]
			},
			{
				"name":"Fur family",
				"children":[
				{
					"name":"Daro_0934 ferric uptake regulator, Fur family\tK03711 fur; Fur family transcriptional regulator, ferric uptake regulator"
				}
				]
			},
			{
				"name":"IclR family",
				"children":[
				{
					"name":"Daro_0897 regulatory protein, IclR\tK05818 mhpR; IclR family transcriptional regulator, mhp operon transcriptional activator"
				}
				]
			},
			{
				"name":"CRP\/FNR family",
				"children":[
				{
					"name":"Daro_0248 Cyclic nucleotide-binding protein\tK10914 crp; CRP\/FNR family transcriptional regulator, cyclic AMP receptor protein"
				},
				{
					"name":"Daro_1294 Cyclic nucleotide-binding:Bacterial regulatory protein, Crp\tK10914 crp; CRP\/FNR family transcriptional regulator, cyclic AMP receptor protein"
				},
				{
					"name":"Daro_1047 Cyclic nucleotide-binding:Bacterial regulatory protein, Crp\tK01420 fnr; CRP\/FNR family transcriptional regulator, anaerobic regulatory protein"
				},
				{
					"name":"Daro_3649 Cyclic nucleotide-binding:Bacterial regulatory protein, Crp\tK01420 fnr; CRP\/FNR family transcriptional regulator, anaerobic regulatory protein"
				},
				{
					"name":"Daro_1089 transcriptional regulator, Crp\/Fnr family\tK21555 cooA; CRP\/FNR family transcriptional regulator, carbon monoxide oxidation system transcription regulator"
				},
				{
					"name":"Daro_1036 Cyclic nucleotide-binding protein\tK21563 dnr; CRP\/FNR family transcriptional regulator, dissimilatory nitrate respiration regulator"
				},
				{
					"name":"Daro_1669 transcriptional regulator, Crp\/Fnr family\tK21563 dnr; CRP\/FNR family transcriptional regulator, dissimilatory nitrate respiration regulator"
				},
				{
					"name":"Daro_3198 transcriptional regulator, Crp\/Fnr family\tK21563 dnr; CRP\/FNR family transcriptional regulator, dissimilatory nitrate respiration regulator"
				}
				]
			},
			{
				"name":"Rrf2 family",
				"children":[
				{
					"name":"Daro_1948 transcriptional regulator, BadM\/Rrf2 family\tK13643 iscR; Rrf2 family transcriptional regulator, iron-sulfur cluster assembly transcription factor"
				},
				{
					"name":"Daro_2918 transcriptional regulator, BadM\/Rrf2 family\tK13771 nsrR; Rrf2 family transcriptional regulator, nitric oxide-sensitive transcriptional repressor"
				}
				]
			},
			{
				"name":"ArsR family",
				"children":[
				{
					"name":"Daro_0401 regulatory protein, ArsR\tK03892 arsR; ArsR family transcriptional regulator, arsenate\/arsenite\/antimonite-responsive transcriptional repressor"
				},
				{
					"name":"Daro_0698 transcriptional regulator, ArsR family\tK03892 arsR; ArsR family transcriptional regulator, arsenate\/arsenite\/antimonite-responsive transcriptional repressor"
				},
				{
					"name":"Daro_2641 transcriptional regulator, ArsR family\tK03892 arsR; ArsR family transcriptional regulator, arsenate\/arsenite\/antimonite-responsive transcriptional repressor"
				},
				{
					"name":"Daro_2281 transcriptional regulator, ArsR family\tK21903 cadC; ArsR family transcriptional regulator, lead\/cadmium\/zinc\/bismuth-responsive transcriptional repressor"
				}
				]
			},
			{
				"name":"XRE family"
			},
			{
				"name":"PadR family"
			},
			{
				"name":"Other families",
				"children":[
				{
					"name":"Daro_3757 Biotin--acetyl-CoA-carboxylase ligase\tK03524 birA; BirA family transcriptional regulator, biotin operon repressor \/ biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]"
				},
				{
					"name":"Daro_3666 Helix-turn-helix, Fis-type\tK03557 fis; Fis family transcriptional regulator, factor for inversion stimulation protein"
				},
				{
					"name":"Daro_1000 GAF modulated sigma54 specific transcriptional regulator, Fis family\tK21405 acoR; sigma-54 dependent transcriptional regulator, acetoin dehydrogenase operon transcriptional activator AcoR"
				},
				{
					"name":"Daro_1017 GAF modulated sigma54 specific transcriptional regulator, Fis family\tK21405 acoR; sigma-54 dependent transcriptional regulator, acetoin dehydrogenase operon transcriptional activator AcoR"
				},
				{
					"name":"Daro_1487 Helix-turn-helix, Fis-type:Nif-specific regulatory protein\tK02584 nifA; Nif-specific regulatory protein"
				},
				{
					"name":"Daro_1477 Molybdenum-binding protein, N-terminal:Molybdenum-pterin binding protein\tK02019 modE; molybdate transport system regulatory protein"
				},
				{
					"name":"Daro_1478 Molybdenum-pterin binding protein\tK02019 modE; molybdate transport system regulatory protein"
				}
				]
			}
			]
		},
		{
			"name":"Ribbon-helix-helix",
			"children":[
			{
				"name":"CopG family",
				"children":[
				{
					"name":"Daro_0076 transcriptional regulator, CopG family\tK07722 nikR; CopG family transcriptional regulator, nickel-responsive regulator"
				},
				{
					"name":"Daro_3947 transcriptional regulator, CopG family\tK07722 nikR; CopG family transcriptional regulator, nickel-responsive regulator"
				}
				]
			},
			{
				"name":"Other families"
			}
			]
		},
		{
			"name":"Other transcription factors",
			"children":[
			{
				"name":"BglG family"
			},
			{
				"name":"Others",
				"children":[
				{
					"name":"Daro_2905 transcriptional regulator, BolA protein family\tK05527 bolA; BolA family transcriptional regulator, general stress-responsive regulator"
				},
				{
					"name":"Daro_2219 ParB-like nuclease\tK03497 parB; ParB family transcriptional regulator, chromosome partitioning protein"
				},
				{
					"name":"Daro_2542 ParB family protein\tK03497 parB; ParB family transcriptional regulator, chromosome partitioning protein"
				},
				{
					"name":"Daro_3014 ParB family protein\tK03497 parB; ParB family transcriptional regulator, chromosome partitioning protein"
				},
				{
					"name":"Daro_4106 chromosome segregation DNA-binding protein\tK03497 parB; ParB family transcriptional regulator, chromosome partitioning protein"
				},
				{
					"name":"Daro_0930 heat-inducible transcription repressor HrcA\tK03705 hrcA; heat-inducible transcriptional repressor"
				},
				{
					"name":"Daro_0386 Phenylacetic acid degradation operon negative regulatory protein paaX\tK02616 paaX; phenylacetic acid degradation operon negative regulatory protein"
				},
				{
					"name":"Daro_3891 Phosphoribosyltransferase\tK02825 pyrR; pyrimidine operon attenuation protein \/ uracil phosphoribosyltransferase [EC:2.4.2.9]"
				},
				{
					"name":"Daro_2246 Prophage CP4-57 regulatory\tK07733 alpA; prophage regulatory protein"
				},
				{
					"name":"Daro_2566 Prophage CP4-57 regulatory\tK07733 alpA; prophage regulatory protein"
				},
				{
					"name":"Daro_0091 negative transcriptional regulator\tK07734 paiB; transcriptional regulator"
				},
				{
					"name":"Daro_3893 Protein of unknown function DUF179\tK07735 algH; putative transcriptional regulator"
				},
				{
					"name":"Daro_2447 transcriptional regulator, TraR\/DksA family\tK06204 dksA; RNA polymerase-binding transcription factor"
				},
				{
					"name":"Daro_0604 Protein of unknown function DUF193\tK07738 nrdR; transcriptional repressor NrdR"
				},
				{
					"name":"Daro_3507 Protein of unknown function UPF0040\tK03925 mraZ; transcriptional regulator MraZ"
				}
				]
			}
			]
		}
		]
	}
	]
}