{
	"name":"dct04031",
	"children":[
	{
		"name":"Heterotrimeric G-proteins",
		"children":[
		{
			"name":"Alpha Subunits",
			"children":[
			{
				"name":"Alpha type 1 (Gi\/o) [OT]",
				"children":[
				{
					"name":"110104295 guanine nucleotide-binding protein alpha-2 subunit isoform X6\tK19729 GNAT3; guanine nucleotide-binding protein G(t) subunit alpha 3"
				}
				]
			},
			{
				"name":"Alpha type 2 (Gs)"
			},
			{
				"name":"Alpha type 3 (Gq\/11) [OT]"
			},
			{
				"name":"Alpha type 4 (G12\/13)"
			},
			{
				"name":"Alpha others - lower eukaryotes"
			}
			]
		},
		{
			"name":"Beta Subunits",
			"children":[
			{
				"name":"Beta [OT]",
				"children":[
				{
					"name":"110115474 guanine nucleotide-binding protein subunit beta\tK04536 GNB1; guanine nucleotide-binding protein G(I)\/G(S)\/G(T) subunit beta-1"
				}
				]
			}
			]
		},
		{
			"name":"Gamma Subunits",
			"children":[
			{
				"name":"Gamma [OT]",
				"children":[
				{
					"name":"110097760 guanine nucleotide-binding protein subunit gamma 1\tK24772 GG1_2; guanine nucleotide-binding protein subunit gamma 1\/2, plant"
				},
				{
					"name":"110104627 guanine nucleotide-binding protein subunit gamma 2-like\tK24772 GG1_2; guanine nucleotide-binding protein subunit gamma 1\/2, plant"
				},
				{
					"name":"110105341 guanine nucleotide-binding protein subunit gamma 2 isoform X2\tK24772 GG1_2; guanine nucleotide-binding protein subunit gamma 1\/2, plant"
				},
				{
					"name":"110095832 guanine nucleotide-binding protein subunit gamma 3\tK24773 GG3; guanine nucleotide-binding protein subunit gamma 3, plant"
				},
				{
					"name":"110109130 keratin-associated protein 4-12\tK24773 GG3; guanine nucleotide-binding protein subunit gamma 3, plant"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Small (monomeric) G-proteins",
		"children":[
		{
			"name":"Ras Family",
			"children":[
			{
				"name":"Ras [OT]"
			},
			{
				"name":"Rit"
			},
			{
				"name":"Ral"
			},
			{
				"name":"Rap [OT]"
			},
			{
				"name":"Di-Ras [OT]"
			},
			{
				"name":"RasD"
			},
			{
				"name":"Rad\/Gem\/Kir [OT]"
			},
			{
				"name":"Rheb"
			},
			{
				"name":"Nki-Ras"
			},
			{
				"name":"Others"
			}
			]
		},
		{
			"name":"Rho Family",
			"children":[
			{
				"name":"RhoA\/B\/C [OT]"
			},
			{
				"name":"Rnd [OT]"
			},
			{
				"name":"Rac\/Cdc42 [OT]",
				"children":[
				{
					"name":"110095808 rac-like GTP-binding protein 5\tK04392 RAC1; Ras-related C3 botulinum toxin substrate 1"
				},
				{
					"name":"110106047 rac-like GTP-binding protein 5\tK04392 RAC1; Ras-related C3 botulinum toxin substrate 1"
				},
				{
					"name":"110112171 rac-like GTP-binding protein 5\tK04392 RAC1; Ras-related C3 botulinum toxin substrate 1"
				},
				{
					"name":"110112855 rac-like GTP-binding protein 5\tK04392 RAC1; Ras-related C3 botulinum toxin substrate 1"
				},
				{
					"name":"110113754 rac-like GTP-binding protein ARAC4\tK04392 RAC1; Ras-related C3 botulinum toxin substrate 1"
				},
				{
					"name":"110113870 rac-like GTP-binding protein 2\tK04392 RAC1; Ras-related C3 botulinum toxin substrate 1"
				},
				{
					"name":"110115341 rac-like GTP-binding protein 3\tK04392 RAC1; Ras-related C3 botulinum toxin substrate 1"
				}
				]
			},
			{
				"name":"RhoBTB"
			},
			{
				"name":"Miro",
				"children":[
				{
					"name":"110101624 mitochondrial Rho GTPase 1\tK07870 RHOT1; mitochondrial Rho GTPase 1 [EC:3.6.5.-]"
				}
				]
			},
			{
				"name":"Others"
			}
			]
		},
		{
			"name":"Rab Family",
			"children":[
			{
				"name":"Rab1\/35 [OT]",
				"children":[
				{
					"name":"110093829 GTP-binding protein YPTM2\tK07874 RAB1A; Ras-related protein Rab-1A"
				},
				{
					"name":"110103613 GTP-binding protein YPTM2\tK07874 RAB1A; Ras-related protein Rab-1A"
				},
				{
					"name":"110105640 ras-related protein RIC1 isoform X1\tK07874 RAB1A; Ras-related protein Rab-1A"
				}
				]
			},
			{
				"name":"Rab2\/4\/14 [OT]",
				"children":[
				{
					"name":"110092046 ras-related protein RABB1c-like\tK07877 RAB2A; Ras-related protein Rab-2A"
				},
				{
					"name":"110099380 ras-related protein RABB1c\tK07877 RAB2A; Ras-related protein Rab-2A"
				},
				{
					"name":"110114714 ras-related protein RABB1c\tK07877 RAB2A; Ras-related protein Rab-2A"
				}
				]
			},
			{
				"name":"Rab3\/27 [OT]"
			},
			{
				"name":"Rab5\/17\/22\/31 [OT]",
				"children":[
				{
					"name":"110092817 ras-related protein Rab5A\tK07887 RAB5A; Ras-related protein Rab-5A"
				},
				{
					"name":"110101277 ras-related protein RABF1 isoform X2\tK07887 RAB5A; Ras-related protein Rab-5A"
				},
				{
					"name":"110112640 ras-related protein RHN1\tK07887 RAB5A; Ras-related protein Rab-5A"
				}
				]
			},
			{
				"name":"Rab6\/41 [OT]",
				"children":[
				{
					"name":"110097984 ras-related protein RABH1e\tK07893 RAB6A_C_D; Ras-related protein Rab-6A\/C\/D [EC:3.6.5.2]"
				},
				{
					"name":"110108560 ras-related protein RABH1b\tK07893 RAB6A_C_D; Ras-related protein Rab-6A\/C\/D [EC:3.6.5.2]"
				}
				]
			},
			{
				"name":"Rab7\/9 [OT]",
				"children":[
				{
					"name":"110092285 ras-related protein Rab7-like isoform X1\tK07897 RAB7A; Ras-related protein Rab-7A [EC:3.6.5.2]"
				},
				{
					"name":"110094973 ras-related protein Rab7-like\tK07897 RAB7A; Ras-related protein Rab-7A [EC:3.6.5.2]"
				},
				{
					"name":"110095879 ras-related protein Rab7\tK07897 RAB7A; Ras-related protein Rab-7A [EC:3.6.5.2]"
				},
				{
					"name":"110106159 ras-related protein Rab7 isoform X1\tK07897 RAB7A; Ras-related protein Rab-7A [EC:3.6.5.2]"
				}
				]
			},
			{
				"name":"Rab8\/10\/13 [OT]",
				"children":[
				{
					"name":"110095048 ras-related protein RABE1c-like isoform X1\tK07901 RAB8A; Ras-related protein Rab-8A"
				},
				{
					"name":"110097774 ras-related protein RABE1a-like isoform X1\tK07901 RAB8A; Ras-related protein Rab-8A"
				},
				{
					"name":"110104476 ras-related protein RABE1c\tK07901 RAB8A; Ras-related protein Rab-8A"
				}
				]
			},
			{
				"name":"Rab11\/25 [OT]",
				"children":[
				{
					"name":"110091936 ras-related protein RABA1f\tK07904 RAB11A; Ras-related protein Rab-11A"
				},
				{
					"name":"110093387 ras-related protein RABA1f-like isoform X1\tK07904 RAB11A; Ras-related protein Rab-11A"
				},
				{
					"name":"110094405 ras-related protein RABA1f-like\tK07904 RAB11A; Ras-related protein Rab-11A"
				},
				{
					"name":"110094986 ras-related protein RABA1d-like\tK07904 RAB11A; Ras-related protein Rab-11A"
				},
				{
					"name":"110096963 ras-related protein RABA2a-like\tK07904 RAB11A; Ras-related protein Rab-11A"
				},
				{
					"name":"110103594 ras-related protein Rab2BV-like\tK07904 RAB11A; Ras-related protein Rab-11A"
				},
				{
					"name":"110104868 ras-related protein RIC2\tK07904 RAB11A; Ras-related protein Rab-11A"
				},
				{
					"name":"110114166 ras-related protein Rab11C-like\tK07904 RAB11A; Ras-related protein Rab-11A"
				},
				{
					"name":"110115688 ras-related protein RIC2\tK07904 RAB11A; Ras-related protein Rab-11A"
				}
				]
			},
			{
				"name":"Rab12\/18",
				"children":[
				{
					"name":"110097656 ras-related protein RABC2a\tK07910 RAB18; Ras-related protein Rab-18"
				},
				{
					"name":"110104147 ras-related protein RABC1-like isoform X1\tK07910 RAB18; Ras-related protein Rab-18"
				},
				{
					"name":"110105133 ras-related protein RABC2a\tK07910 RAB18; Ras-related protein Rab-18"
				},
				{
					"name":"110115959 ras-related protein RABC1\tK07910 RAB18; Ras-related protein Rab-18"
				}
				]
			},
			{
				"name":"Rab15"
			},
			{
				"name":"Rab19\/30\/43 [OT]"
			},
			{
				"name":"Rab20\/21\/24 [OT]"
			},
			{
				"name":"Rab23"
			},
			{
				"name":"Rab26\/37"
			},
			{
				"name":"Rab28"
			},
			{
				"name":"Rab29\/32\/38 [OT]"
			},
			{
				"name":"Rab33"
			},
			{
				"name":"Rab34\/36"
			},
			{
				"name":"Rab39\/42 [OT]"
			},
			{
				"name":"Rab40"
			},
			{
				"name":"Rab45"
			},
			{
				"name":"Rab-like"
			},
			{
				"name":"Others",
				"children":[
				{
					"name":"110094198 ras-related protein RABA5c\tK07976 RAB; Rab family, other"
				},
				{
					"name":"110106578 septum-promoting GTP-binding protein 1 isoform X1\tK07976 RAB; Rab family, other"
				}
				]
			}
			]
		},
		{
			"name":"Ran Family",
			"children":[
			{
				"name":"Ran",
				"children":[
				{
					"name":"110110197 GTP-binding nuclear protein Ran1-like\tK07936 RAN; GTP-binding nuclear protein Ran"
				},
				{
					"name":"110110915 GTP-binding nuclear protein Ran-A1-like\tK07936 RAN; GTP-binding nuclear protein Ran"
				},
				{
					"name":"110114859 GTP-binding nuclear protein Ran-A1\tK07936 RAN; GTP-binding nuclear protein Ran"
				}
				]
			}
			]
		},
		{
			"name":"Arf\/Sar Family",
			"children":[
			{
				"name":"Arf [OT]",
				"children":[
				{
					"name":"110098236 ADP-ribosylation factor 2\tK07937 ARF1_2; ADP-ribosylation factor 1\/2"
				},
				{
					"name":"110099281 ADP-ribosylation factor 1\tK07937 ARF1_2; ADP-ribosylation factor 1\/2"
				},
				{
					"name":"110102761 ADP-ribosylation factor\tK07937 ARF1_2; ADP-ribosylation factor 1\/2"
				},
				{
					"name":"110107119 ADP-ribosylation factor 2\tK07937 ARF1_2; ADP-ribosylation factor 1\/2"
				},
				{
					"name":"110109306 ADP-ribosylation factor\tK07937 ARF1_2; ADP-ribosylation factor 1\/2"
				},
				{
					"name":"110111440 ADP-ribosylation factor\tK07937 ARF1_2; ADP-ribosylation factor 1\/2"
				},
				{
					"name":"110111689 ADP-ribosylation factor 1-like\tK07937 ARF1_2; ADP-ribosylation factor 1\/2"
				},
				{
					"name":"110115155 ADP-ribosylation factor\tK07937 ARF1_2; ADP-ribosylation factor 1\/2"
				}
				]
			},
			{
				"name":"Arl1\/Arl5 [OT]",
				"children":[
				{
					"name":"110101238 ADP-ribosylation factor 3\tK07942 ARL1; ADP-ribosylation factor-like protein 1"
				},
				{
					"name":"110097300 ADP-ribosylation factor-like protein 5\tK07950 ARL5B; ADP-ribosylation factor-like protein 5B"
				}
				]
			},
			{
				"name":"Arl2\/Arl3",
				"children":[
				{
					"name":"110093557 ADP-ribosylation factor-like protein 2\tK07943 ARL2; ADP-ribosylation factor-like protein 2"
				}
				]
			},
			{
				"name":"Arl4\/Arl7"
			},
			{
				"name":"Arl6"
			},
			{
				"name":"Arp",
				"children":[
				{
					"name":"110100160 ADP-ribosylation factor-related protein 1 isoform X2\tK07952 ARFRP1; ADP-ribosylation factor related protein 1"
				}
				]
			},
			{
				"name":"Sar",
				"children":[
				{
					"name":"110100850 GTP-binding protein SAR1A\tK07953 SAR1; GTP-binding protein SAR1 [EC:3.6.5.-]"
				},
				{
					"name":"110101627 GTP-binding protein SAR1A\tK07953 SAR1; GTP-binding protein SAR1 [EC:3.6.5.-]"
				},
				{
					"name":"110107455 GTP-binding protein SAR1\tK07953 SAR1; GTP-binding protein SAR1 [EC:3.6.5.-]"
				},
				{
					"name":"110113225 GTP-binding protein SAR1A-like\tK07953 SAR1; GTP-binding protein SAR1 [EC:3.6.5.-]"
				}
				]
			},
			{
				"name":"Arl8",
				"children":[
				{
					"name":"110092308 ADP-ribosylation factor-like protein 8a\tK07955 ARL8; ADP-ribosylation factor-like protein 8"
				},
				{
					"name":"110098161 ADP-ribosylation factor-like protein 8c isoform X1\tK07955 ARL8; ADP-ribosylation factor-like protein 8"
				},
				{
					"name":"110105882 ADP-ribosylation factor-like protein 8b\tK07955 ARL8; ADP-ribosylation factor-like protein 8"
				}
				]
			},
			{
				"name":"Others"
			}
			]
		},
		{
			"name":"Unclassified",
			"children":[
			{
				"name":"110097626 small GTPase LIP1-like\tK07933 RABL3; Rab-like protein 3"
			},
			{
				"name":"110109520 small GTPase LIP1-like isoform X1\tK07933 RABL3; Rab-like protein 3"
			},
			{
				"name":"110104022 signal recognition particle receptor subunit beta-like\tK12272 SRPRB; signal recognition particle receptor subunit beta"
			}
			]
		}
		]
	}
	]
}