{
	"name":"dgr01001",
	"children":[
	{
		"name":"Serine\/threonine kinases: AGC group",
		"children":[
		{
			"name":"PKA family",
			"children":[
			{
				"name":"6561425 cAMP-dependent protein kinase catalytic subunit 1\tK04345 PKA; protein kinase A [EC:2.7.11.11]"
			},
			{
				"name":"6569722 cAMP-dependent protein kinase catalytic subunit 2 isoform X1\tK04345 PKA; protein kinase A [EC:2.7.11.11]"
			}
			]
		},
		{
			"name":"PKG family",
			"children":[
			{
				"name":"6561993 cGMP-dependent protein kinase, isozyme 1\tK07376 PRKG1; cGMP-dependent protein kinase 1 [EC:2.7.11.12]"
			},
			{
				"name":"6562037 cGMP-dependent protein kinase 1 isoform X1\tK07376 PRKG1; cGMP-dependent protein kinase 1 [EC:2.7.11.12]"
			},
			{
				"name":"6566754 cGMP-dependent protein kinase, isozyme 2 forms cD5\/T2 isoform X2\tK07376 PRKG1; cGMP-dependent protein kinase 1 [EC:2.7.11.12]"
			}
			]
		},
		{
			"name":"PKC family [OT]",
			"children":[
			{
				"name":"6568865 protein kinase C, brain isozyme isoform X3\tK02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]"
			},
			{
				"name":"6568866 protein kinase C, eye isozyme\tK02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]"
			},
			{
				"name":"6569320 putative protein kinase C delta type homolog isoform X1\tK06068 PRKCD; novel protein kinase C delta type [EC:2.7.11.13]"
			},
			{
				"name":"6563904 protein kinase C isoform X2\tK18050 PRKCE; novel protein kinase C epsilon type [EC:2.7.11.13]"
			},
			{
				"name":"6559922 atypical protein kinase C isoform X5\tK06069 PRKCI; atypical protein kinase C iota type [EC:2.7.11.13]"
			}
			]
		},
		{
			"name":"PKN family",
			"children":[
			{
				"name":"6560622 serine\/threonine-protein kinase N isoform X1\tK23691 PKN2; serine\/threonine-protein kinase N2 [EC:2.7.11.13]"
			}
			]
		},
		{
			"name":"AUR family [OT]",
			"children":[
			{
				"name":"6567604 aurora kinase C\tK11481 AURKA; aurora kinase A [EC:2.7.11.1]"
			},
			{
				"name":"6567101 aurora kinase B\tK11479 AURKB; aurora kinase B [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"PDK1 family",
			"children":[
			{
				"name":"6556798 3-phosphoinositide-dependent protein kinase 1 isoform X1\tK06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"AKT\/PKB family",
			"children":[
			{
				"name":"6564024 RAC serine\/threonine-protein kinase\tK04456 AKT; RAC serine\/threonine-protein kinase [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"SGK family [OT]"
		},
		{
			"name":"RSK family [OT]",
			"children":[
			{
				"name":"116805666 LOW QUALITY PROTEIN: ribosomal protein S6 kinase 2 beta\tK04373 RPS6KA; ribosomal protein S6 kinase alpha-1\/2\/3\/6 [EC:2.7.11.1]"
			},
			{
				"name":"6557203 chromosomal serine\/threonine-protein kinase JIL-1\tK04445 RPS6KA5; ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1]"
			},
			{
				"name":"6557538 ribosomal protein S6 kinase beta-2 isoform X2\tK04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]"
			},
			{
				"name":"6563868 ribosomal protein S6 kinase delta-1 isoform X1\tK20839 RSKL; ribosomal protein S6 kinase-like"
			}
			]
		},
		{
			"name":"NDR family",
			"children":[
			{
				"name":"6558504 serine\/threonine-protein kinase tricornered\tK08790 STK38; serine\/threonine kinase 38 [EC:2.7.11.1]"
			},
			{
				"name":"6569834 serine\/threonine-protein kinase Warts\tK08791 LATS1_2; serine\/threonine-protein kinase LATS1\/2 [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"MAST family [OT]",
			"children":[
			{
				"name":"6557052 LOW QUALITY PROTEIN: microtubule-associated serine\/threonine-protein kinase 1\tK08789 MAST; MAST-subfamily protein kinase [EC:2.7.11.37]"
			},
			{
				"name":"6568423 serine\/threonine-protein kinase greatwall isoform X2\tK16309 MASTL; serine\/threonine-protein kinase greatwall [EC:2.7.11.36]"
			}
			]
		},
		{
			"name":"YANK family",
			"children":[
			{
				"name":"6563261 serine\/threonine-protein kinase 32A isoform X1\tK08793 STK32; serine\/threonine kinase 32 [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"DMPK family [OT]",
			"children":[
			{
				"name":"6565215 rho-associated protein kinase 1 isoform X2\tK04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.39]"
			},
			{
				"name":"6561117 serine\/threonine-protein kinase Genghis Khan\tK16307 CDC42BP; serine\/threonine-protein kinase MRCK [EC:2.7.11.1]"
			},
			{
				"name":"6556622 citron rho-interacting kinase\tK16308 CIT; citron Rho-interacting kinase [EC:2.7.11.35]"
			}
			]
		},
		{
			"name":"GRK family [OT]",
			"children":[
			{
				"name":"6559369 G protein-coupled receptor kinase 1\tK00910 ADRBK; beta-adrenergic-receptor kinase [EC:2.7.11.15]"
			},
			{
				"name":"6567694 G protein-coupled receptor kinase 2\tK08291 GRK4_5_6; G protein-coupled receptor kinase [EC:2.7.11.16]"
			}
			]
		},
		{
			"name":"Other",
			"children":[
			{
				"name":"6564903 serine\/threonine-protein kinase S6KL\tK17529 SGK494; uncharacterized serine\/threonine-protein kinase SgK494 [EC:2.7.11.1]"
			}
			]
		}
		]
	},
	{
		"name":"Serine\/threonine kinases: CAMK group",
		"children":[
		{
			"name":"CAMK1 family [OT]",
			"children":[
			{
				"name":"6570251 calcium\/calmodulin-dependent protein kinase type 1 isoform X1\tK08794 CAMK1; calcium\/calmodulin-dependent protein kinase I [EC:2.7.11.17]"
			}
			]
		},
		{
			"name":"CAMK2 family",
			"children":[
			{
				"name":"6570272 calcium\/calmodulin-dependent protein kinase type II alpha chain isoform X4\tK04515 CAMK2; calcium\/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]"
			}
			]
		},
		{
			"name":"CAMKL family",
			"children":[
			{
				"name":"6557290 serine\/threonine-protein kinase BRSK1\tK08796 BRSK; BR serine\/threonine kinase [EC:2.7.11.1]"
			},
			{
				"name":"6570236 serine\/threonine-protein kinase grp\tK02216 CHEK1; serine\/threonine-protein kinase CHEK1 [EC:2.7.11.1]"
			},
			{
				"name":"6560886 cAMP-dependent protein kinase catalytic subunit isoform X3\tK08798 MARK; MAP\/microtubule affinity-regulating kinase [EC:2.7.11.1]"
			},
			{
				"name":"6567796 serine\/threonine-protein kinase MARK2\tK08798 MARK; MAP\/microtubule affinity-regulating kinase [EC:2.7.11.1]"
			},
			{
				"name":"6566770 serine\/threonine-protein kinase SIK3\tK16310 NIM1; serine\/threonine-protein kinase NIM1 [EC:2.7.11.1]"
			},
			{
				"name":"6565234 5'-AMP-activated protein kinase catalytic subunit alpha-2\tK07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]"
			},
			{
				"name":"6566281 uncharacterized protein LOC6566281\tK16311 SIK2; serine\/threonine-protein kinase SIK2 [EC:2.7.11.1]"
			},
			{
				"name":"6560691 serine\/threonine-protein kinase par-1 isoform X1\tK19009 SIK3; serine\/threonine-protein kinase SIK3 [EC:2.7.11.1]"
			},
			{
				"name":"6560047 SNF-related serine\/threonine-protein kinase\tK08802 SNRK; SNF related kinase [EC:2.7.11.1]"
			},
			{
				"name":"6564127 serine\/threonine-protein kinase STK11\tK07298 STK11; serine\/threonine-protein kinase 11 [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"DAPK family"
		},
		{
			"name":"DCAMKL family",
			"children":[
			{
				"name":"116805688 serine\/threonine-protein kinase GA29083 isoform X1\tK08805 DCLK1_2; doublecortin-like kinase 1\/2 [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"MAPKAPK family [OT]",
			"children":[
			{
				"name":"6565865 MAP kinase-activated protein kinase 2\tK04443 MAPKAPK2; mitogen-activated protein kinase-activated protein kinase 2 [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"MLCK family",
			"children":[
			{
				"name":"6569001 myosin light chain kinase, smooth muscle\tK00907 MYLK; myosin-light-chain kinase [EC:2.7.11.18]"
			},
			{
				"name":"6557276 titin\tK12567 TTN; titin [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"PHK family",
			"children":[
			{
				"name":"6566254 phosphorylase b kinase gamma catalytic chain, skeletal muscle\/heart isoform isoform X2\tK00871 PHKG; phosphorylase kinase gamma subunit [EC:2.7.11.19]"
			}
			]
		},
		{
			"name":"PIM family [OT]"
		},
		{
			"name":"PKD family",
			"children":[
			{
				"name":"6563178 serine\/threonine-protein kinase D3\tK06070 PKD; protein kinase D [EC:2.7.11.13]"
			}
			]
		},
		{
			"name":"PSK family"
		},
		{
			"name":"RAD53 family",
			"children":[
			{
				"name":"6566473 ovarian-specific serine\/threonine-protein kinase Lok isoform X2\tK06641 CHEK2; serine\/threonine-protein kinase CHEK2 [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"Trio family [OT]",
			"children":[
			{
				"name":"6558485 triple functional domain protein isoform X1\tK08810 TRIO; triple functional domain protein [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"TSSK family",
			"children":[
			{
				"name":"6561892 testis-specific serine\/threonine-protein kinase 3\tK08811 TSSK; testis-specific serine kinase [EC:2.7.11.1]"
			},
			{
				"name":"6564267 testis-specific serine\/threonine-protein kinase 1\tK08811 TSSK; testis-specific serine kinase [EC:2.7.11.1]"
			},
			{
				"name":"6564268 testis-specific serine\/threonine-protein kinase 1\tK08811 TSSK; testis-specific serine kinase [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"CDPK family"
		},
		{
			"name":"CASK family",
			"children":[
			{
				"name":"6564400 peripheral plasma membrane protein CASK isoform X8\tK06103 CASK; calcium\/calmodulin-dependent serine protein kinase [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"Trbl family",
			"children":[
			{
				"name":"6556850 tribbles\tK08814 TRIB1_2; tribbles homolog 1\/2"
			}
			]
		},
		{
			"name":"Other"
		}
		]
	},
	{
		"name":"Serine\/threonine kinases: CK1 group",
		"children":[
		{
			"name":"CK1 family [OT]",
			"children":[
			{
				"name":"6562824 casein kinase I\tK08957 CSNK1A; casein kinase 1, alpha [EC:2.7.11.1]"
			},
			{
				"name":"6564282 casein kinase I\tK08957 CSNK1A; casein kinase 1, alpha [EC:2.7.11.1]"
			},
			{
				"name":"6565079 casein kinase I\tK08957 CSNK1A; casein kinase 1, alpha [EC:2.7.11.1]"
			},
			{
				"name":"6565408 casein kinase I\tK08957 CSNK1A; casein kinase 1, alpha [EC:2.7.11.1]"
			},
			{
				"name":"6567623 casein kinase I\tK08957 CSNK1A; casein kinase 1, alpha [EC:2.7.11.1]"
			},
			{
				"name":"6569386 casein kinase I\tK08957 CSNK1A; casein kinase 1, alpha [EC:2.7.11.1]"
			},
			{
				"name":"6563750 casein kinase I isoform X11\tK08958 CSNK1G; casein kinase 1, gamma [EC:2.7.11.1]"
			},
			{
				"name":"6569788 discs overgrown protein kinase\tK08960 CSNK1E; casein kinase 1, epsilon [EC:2.7.11.1]"
			},
			{
				"name":"6562858 LOW QUALITY PROTEIN: casein kinase I\tK02218 CSNK1; casein kinase 1 [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"TTBK family",
			"children":[
			{
				"name":"6570254 tau-tubulin kinase homolog Asator isoform X3\tK08815 TTBK; tau tubulin kinase [EC:2.7.11.26]"
			}
			]
		},
		{
			"name":"VRK family",
			"children":[
			{
				"name":"6568154 nucleosomal histone kinase 1\tK08816 VRK; vaccinia related kinase [EC:2.7.11.1]"
			}
			]
		}
		]
	},
	{
		"name":"Serine\/threonine kinases: CMGC group",
		"children":[
		{
			"name":"CDK family",
			"children":[
			{
				"name":"6568521 cyclin-dependent kinase 20\tK08817 CDK20; cyclin-dependent kinase 20 [EC:2.7.11.22]"
			},
			{
				"name":"6556991 serine\/threonine-protein kinase PITSLRE isoform X1\tK08818 CDC2L; cell division cycle 2-like [EC:2.7.11.22]"
			},
			{
				"name":"6566951 cyclin-dependent kinase 1\tK02087 CDK1; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]"
			},
			{
				"name":"6568595 cyclin-dependent kinase 2 isoform X1\tK02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]"
			},
			{
				"name":"6559243 cyclin-dependent kinase 4\tK02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]"
			},
			{
				"name":"6559602 cyclin-dependent kinase 5 homolog\tK02090 CDK5; cyclin-dependent kinase 5 [EC:2.7.11.22]"
			},
			{
				"name":"6566064 cyclin-dependent kinase 7\tK02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]"
			},
			{
				"name":"6571734 cyclin-dependent kinase 8\tK02208 CDK8_11; cyclin-dependent kinase 8\/11 [EC:2.7.11.22 2.7.11.23]"
			},
			{
				"name":"6559543 cyclin-dependent kinase 9\tK02211 CDK9; cyclin-dependent kinase 9 [EC:2.7.11.22 2.7.11.23]"
			},
			{
				"name":"6560063 cyclin-dependent kinase 10\tK02449 CDK10; cyclin-dependent kinase 10 [EC:2.7.11.22]"
			},
			{
				"name":"6556996 cyclin-dependent kinase 12\tK08819 CDK12_13; cyclin-dependent kinase 12\/13 [EC:2.7.11.22 2.7.11.23]"
			},
			{
				"name":"6557916 cyclin-dependent kinase 14 isoform X2\tK08821 CDK14; cyclin-dependent kinase 14 [EC:2.7.11.22]"
			}
			]
		},
		{
			"name":"MAPK family [OT]",
			"children":[
			{
				"name":"6567034 mitogen-activated protein kinase ERK-A isoform X1\tK04371 ERK; mitogen-activated protein kinase 1\/3 [EC:2.7.11.24]"
			},
			{
				"name":"6565447 extracellular signal-regulated kinase 7 isoform X1\tK19603 MAPK15; mitogen-activated protein kinase 15 [EC:2.7.11.24]"
			},
			{
				"name":"6567095 stress-activated protein kinase JNK\tK04440 JNK; mitogen-activated protein kinase 8\/9\/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]"
			},
			{
				"name":"6562920 mitogen-activated protein kinase p38b\tK04441 P38; p38 MAP kinase [EC:2.7.11.24]"
			},
			{
				"name":"6563490 mitogen-activated protein kinase p38a\tK04441 P38; p38 MAP kinase [EC:2.7.11.24]"
			},
			{
				"name":"6557597 serine\/threonine-protein kinase NLK2 isoform X1\tK04468 NLK; nemo like kinase [EC:2.7.11.24]"
			}
			]
		},
		{
			"name":"GSK family [OT]",
			"children":[
			{
				"name":"6568581 glycogen synthase kinase-3\tK03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]"
			}
			]
		},
		{
			"name":"CLK family"
		},
		{
			"name":"CDKL family",
			"children":[
			{
				"name":"6562503 cyclin-dependent kinase-like 1 isoform X1\tK08824 CDKL; cyclin-dependent kinase-like [EC:2.7.11.22]"
			}
			]
		},
		{
			"name":"DYRK family [OT]",
			"children":[
			{
				"name":"6565021 serine\/threonine-protein kinase minibrain\tK08825 DYRK1; dual specificity tyrosine-phosphorylation-regulated kinase 1 [EC:2.7.12.1]"
			},
			{
				"name":"6562855 dual specificity tyrosine-phosphorylation-regulated kinase 2\tK18669 DYRK2_3_4; dual specificity tyrosine-phosphorylation-regulated kinase 2\/3\/4 [EC:2.7.12.1]"
			},
			{
				"name":"6557840 homeodomain-interacting protein kinase 2\tK08826 HIPK; homeodomain interacting protein kinase [EC:2.7.11.1]"
			},
			{
				"name":"6557251 serine\/threonine-protein kinase PRP4 homolog\tK08827 PRPF4B; serine\/threonine-protein kinase PRP4 [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"RCK family [OT]",
			"children":[
			{
				"name":"6562645 probable serine\/threonine-protein kinase DDB_G0268078\tK08829 MAK; male germ cell-associated kinase [EC:2.7.11.22]"
			}
			]
		},
		{
			"name":"SRPK family [OT]",
			"children":[
			{
				"name":"6560413 SRSF protein kinase 1\tK15409 SRPK1; serine\/threonine-protein kinase SRPK1 [EC:2.7.11.1]"
			}
			]
		}
		]
	},
	{
		"name":"Serine\/threonine kinases: STE group",
		"children":[
		{
			"name":"STE7 family",
			"children":[
			{
				"name":"6565443 dual specificity mitogen-activated protein kinase kinase dSOR1 isoform X1\tK04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]"
			},
			{
				"name":"6566302 dual specificity mitogen-activated protein kinase kinase 6\tK04432 MAP2K3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]"
			},
			{
				"name":"6567864 dual specificity mitogen-activated protein kinase kinase 4\tK04430 MAP2K4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]"
			}
			]
		},
		{
			"name":"STE20 family",
			"children":[
			{
				"name":"6568662 mitogen-activated protein kinase kinase kinase kinase 5 isoform X1\tK08833 MAP4K5; mitogen-activated protein kinase kinase kinase kinase 5 [EC:2.7.11.1]"
			},
			{
				"name":"6558541 serine\/threonine-protein kinase mig-15 isoform X1\tK08840 TNIK; TRAF2 and NCK interacting kinase [EC:2.7.11.1]"
			},
			{
				"name":"6567118 neither inactivation nor afterpotential protein C\tK08834 MYO3; myosin III [EC:2.7.11.1]"
			},
			{
				"name":"6564430 serine\/threonine-protein kinase OSR1\tK08835 OXSR1; serine\/threonine-protein kinase OSR1\/STK39 [EC:2.7.11.1]"
			},
			{
				"name":"6563835 serine\/threonine-protein kinase PAK 2\tK04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]"
			},
			{
				"name":"6564346 serine\/threonine-protein kinase Pak\tK04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]"
			},
			{
				"name":"6565213 serine\/threonine-protein kinase PAK mbt\tK05736 PAK5; p21-activated kinase 5 [EC:2.7.11.1]"
			},
			{
				"name":"6559572 serine\/threonine-protein kinase 10 isoform X1\tK08836 SLK; STE20-like kinase [EC:2.7.11.1]"
			},
			{
				"name":"6556450 putative serine\/threonine-protein kinase STE20-like\tK08271 STRADA; STE20-related kinase adapter protein alpha"
			},
			{
				"name":"6568702 serine\/threonine-protein kinase hippo\tK04412 STK3; serine\/threonine kinase 3"
			},
			{
				"name":"6567827 serine\/threonine-protein kinase svkA\tK08838 STK24_25_MST4; serine\/threonine-protein kinase 24\/25\/MST4 [EC:2.7.11.1]"
			},
			{
				"name":"6565361 serine\/threonine-protein kinase Tao isoform X1\tK04429 TAO; thousand and one amino acid protein kinase [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"STE11 family",
			"children":[
			{
				"name":"6567297 mitogen-activated protein kinase kinase kinase 4 isoform X1\tK04428 MAP3K4; mitogen-activated protein kinase kinase kinase 4 [EC:2.7.11.25]"
			},
			{
				"name":"6567932 mitogen-activated protein kinase kinase kinase 15 isoform X4\tK04426 MAP3K5; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]"
			}
			]
		},
		{
			"name":"Other"
		}
		]
	},
	{
		"name":"Serine\/threonine kinases: TKL group",
		"children":[
		{
			"name":"IRAK family",
			"children":[
			{
				"name":"6568515 serine\/threonine-protein kinase pelle\tK04730 IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]"
			},
			{
				"name":"6569885 protein Tube\tK04733 IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"LISK family [OT]",
			"children":[
			{
				"name":"6565968 LIM domain kinase 1 isoform X2\tK05743 LIMK1; LIM domain kinase 1 [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"LRRK family"
		},
		{
			"name":"MLK family",
			"children":[
			{
				"name":"116805478 uncharacterized protein LOC116805478 isoform X1\tK04427 MAP3K7; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]"
			},
			{
				"name":"116805724 mitogen-activated protein kinase kinase kinase 7-like isoform X1\tK04427 MAP3K7; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]"
			},
			{
				"name":"116805733 mitogen-activated protein kinase kinase kinase 7-like isoform X3\tK04427 MAP3K7; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]"
			},
			{
				"name":"6569467 mitogen-activated protein kinase kinase kinase 7\tK04427 MAP3K7; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]"
			},
			{
				"name":"6565991 mitogen-activated protein kinase kinase kinase\tK04417 MAP3K9; mitogen-activated protein kinase kinase kinase 9 [EC:2.7.11.25]"
			},
			{
				"name":"6558067 mitogen-activated protein kinase kinase kinase 13-B isoform X1\tK04422 MAP3K13; mitogen-activated protein kinase kinase kinase 13 [EC:2.7.11.25]"
			},
			{
				"name":"6557157 integrin-linked protein kinase\tK06272 ILK; integrin-linked kinase [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"RAF family [OT]",
			"children":[
			{
				"name":"6564665 raf homolog serine\/threonine-protein kinase Raf isoform X1\tK04365 BRAF; B-Raf proto-oncogene serine\/threonine-protein kinase [EC:2.7.11.1]"
			},
			{
				"name":"6563880 kinase suppressor of Ras 2\tK18529 KSR2; kinase suppressor of Ras 2 [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"RIPK family [OT]"
		},
		{
			"name":"Other"
		}
		]
	},
	{
		"name":"Serine\/threonine kinases: Other",
		"children":[
		{
			"name":"RGC family [OT]",
			"children":[
			{
				"name":"6559935 atrial natriuretic peptide receptor 1\tK12323 NPR1; atrial natriuretic peptide receptor 1 [EC:4.6.1.2]"
			},
			{
				"name":"6571759 atrial natriuretic peptide receptor 1 isoform X1\tK12323 NPR1; atrial natriuretic peptide receptor 1 [EC:4.6.1.2]"
			},
			{
				"name":"6564343 uncharacterized protein LOC6564343\tK12322 GUCY2F; guanylate cyclase 2F [EC:4.6.1.2]"
			}
			]
		},
		{
			"name":"BUB family",
			"children":[
			{
				"name":"6560139 uncharacterized protein LOC6560139\tK02178 BUB1; checkpoint serine\/threonine-protein kinase [EC:2.7.11.1]"
			},
			{
				"name":"6566908 uncharacterized protein LOC6566908\tK02178 BUB1; checkpoint serine\/threonine-protein kinase [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"Bud32 family",
			"children":[
			{
				"name":"6558662 EKC\/KEOPS complex subunit TP53RK\tK08851 TP53RK; TP53 regulating kinase and related kinases [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"CAMKK family",
			"children":[
			{
				"name":"116806045 calcium\/calmodulin-dependent protein kinase kinase 1\tK07359 CAMKK2; calcium\/calmodulin-dependent protein kinase kinase 2 [EC:2.7.11.17]"
			}
			]
		},
		{
			"name":"CDC7 family",
			"children":[
			{
				"name":"6561801 cell division cycle 7-related protein kinase\tK02214 CDC7; cell division control protein 7 [EC:2.7.11.1]"
			},
			{
				"name":"6566107 cell division cycle 7-related protein kinase isoform X1\tK02214 CDC7; cell division control protein 7 [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"CK2 family",
			"children":[
			{
				"name":"6570015 casein kinase II subunit alpha\tK03097 CSNK2A; casein kinase II subunit alpha [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"Haspin family",
			"children":[
			{
				"name":"6567179 serine\/threonine-protein kinase haspin homolog isoform X1\tK16315 GSG2; serine\/threonine-protein kinase haspin [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"IKK family [OT]",
			"children":[
			{
				"name":"6563402 inhibitor of nuclear factor kappa-B kinase subunit beta\tK07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]"
			},
			{
				"name":"6562287 serine\/threonine-protein kinase TBK1\tK05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]"
			}
			]
		},
		{
			"name":"IRE family",
			"children":[
			{
				"name":"6567778 serine\/threonine-protein kinase\/endoribonuclease IRE1\tK08852 ERN1; serine\/threonine-protein kinase\/endoribonuclease IRE1 [EC:2.7.11.1 3.1.26.-]"
			}
			]
		},
		{
			"name":"MOS family"
		},
		{
			"name":"NAK family [OT]",
			"children":[
			{
				"name":"6561866 AP2-associated protein kinase 1 isoform X1\tK08853 AAK; AP2-associated kinase [EC:2.7.11.1]"
			},
			{
				"name":"6564091 cyclin-G-associated kinase\tK08855 GAK; cyclin G-associated kinase [EC:2.7.11.1]"
			},
			{
				"name":"6563434 serine\/threonine-protein kinase 16\tK08856 STK16; serine\/threonine kinase 16 [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"NEK family",
			"children":[
			{
				"name":"6565818 serine\/threonine-protein kinase Nek1\tK20872 NEK2; serine\/threonine-protein kinase Nek2 [EC:2.7.11.1]"
			},
			{
				"name":"6567737 serine\/threonine-protein kinase Nek8\tK20877 NEK8; serine\/threonine-protein kinase Nek8 [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"NKF1 family",
			"children":[
			{
				"name":"6559072 serine\/threonine-protein kinase meng-po isoform X2\tK08858 SBK; serine\/threonine-protein kinase SBK [EC:2.7.11.1]"
			},
			{
				"name":"6562516 serine\/threonine-protein kinase meng-po\tK08858 SBK; serine\/threonine-protein kinase SBK [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"NKF2 family"
		},
		{
			"name":"NKF3 family"
		},
		{
			"name":"NKF4 family"
		},
		{
			"name":"NKF5 family"
		},
		{
			"name":"NRBP family",
			"children":[
			{
				"name":"6564359 nuclear receptor-binding protein homolog\tK08875 NRBP; nuclear receptor-binding protein"
			}
			]
		},
		{
			"name":"PEK family [OT]",
			"children":[
			{
				"name":"6567621 eukaryotic translation initiation factor 2-alpha kinase isoform X1\tK08860 EIF2AK3; eukaryotic translation initiation factor 2-alpha kinase 3 [EC:2.7.11.1]"
			},
			{
				"name":"6567684 eIF-2-alpha kinase GCN2\tK16196 EIF2AK4; eukaryotic translation initiation factor 2-alpha kinase 4 [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"PLK family [OT]",
			"children":[
			{
				"name":"6558478 serine\/threonine-protein kinase polo\tK06631 PLK1; polo-like kinase 1 [EC:2.7.11.21]"
			},
			{
				"name":"6556999 serine\/threonine-protein kinase PLK4\tK08863 PLK4; polo-like kinase 4 [EC:2.7.11.21]"
			}
			]
		},
		{
			"name":"SCY1 family [OT]",
			"children":[
			{
				"name":"6569638 N-terminal kinase-like protein\tK08876 SCYL1; SCY1-like protein 1"
			},
			{
				"name":"6557040 SCY1-like protein 2 isoform X1\tK17541 SCYL2; SCY1-like protein 2"
			},
			{
				"name":"6567257 SCY1-like protein 2\tK17541 SCYL2; SCY1-like protein 2"
			},
			{
				"name":"6566412 protein-associating with the carboxyl-terminal domain of ezrin\tK17542 SCYL3; SCY1-like protein 3"
			}
			]
		},
		{
			"name":"Slob family",
			"children":[
			{
				"name":"6560850 PX domain-containing protein kinase-like protein\tK17543 PXK; PX domain-containing protein kinase-like protein"
			}
			]
		},
		{
			"name":"TBCK family",
			"children":[
			{
				"name":"6565077 TBC domain-containing protein kinase-like protein isoform X2\tK17544 TBCK; TBC domain-containing protein kinase-like protein"
			}
			]
		},
		{
			"name":"TLK family",
			"children":[
			{
				"name":"6565958 neurogenic protein mastermind\tK08864 TLK; tousled-like kinase [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"TOPK family",
			"children":[
			{
				"name":"6564574 lymphokine-activated killer T-cell-originated protein kinase\tK08865 PBK; PDZ-binding kinase [EC:2.7.12.2]"
			}
			]
		},
		{
			"name":"TTK family",
			"children":[
			{
				"name":"6563948 dual specificity protein kinase TTK\tK08866 TTK; serine\/threonine-protein kinase TTK\/MPS1 [EC:2.7.12.1]"
			}
			]
		},
		{
			"name":"ULK family [OT]",
			"children":[
			{
				"name":"6565432 serine\/threonine-protein kinase fused\tK06228 FU; fused [EC:2.7.11.1]"
			},
			{
				"name":"6557110 serine\/threonine-protein kinase unc-51\tK08269 ULK2; serine\/threonine-protein kinase ULK2 [EC:2.7.11.1]"
			},
			{
				"name":"6570039 serine\/threonine-protein kinase ULK3 isoform X1\tK21358 ULK3; serine\/threonine-protein kinase ULK3 [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"VPS15 family",
			"children":[
			{
				"name":"6568620 phosphoinositide 3-kinase regulatory subunit 4\tK08333 PIK3R4; phosphoinositide-3-kinase, regulatory subunit 4 [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"WEE family",
			"children":[
			{
				"name":"6558127 membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase isoform X1\tK06633 PKMYT; membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase [EC:2.7.11.1]"
			},
			{
				"name":"6566886 membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase\tK06633 PKMYT; membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase [EC:2.7.11.1]"
			},
			{
				"name":"6566976 wee1-like protein kinase\tK06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"Wnk family",
			"children":[
			{
				"name":"6556968 uncharacterized protein LOC6556968\tK08867 WNK; WNK lysine deficient protein kinase [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"ABC1 family",
			"children":[
			{
				"name":"6557642 uncharacterized aarF domain-containing protein kinase 5 isoform X2\tK08869 ADCK; aarF domain-containing kinase"
			},
			{
				"name":"6559394 LOW QUALITY PROTEIN: aarF domain-containing kinase 1\tK08869 ADCK; aarF domain-containing kinase"
			},
			{
				"name":"6569221 atypical kinase COQ8B, mitochondrial\tK08869 ADCK; aarF domain-containing kinase"
			}
			]
		},
		{
			"name":"Alpha family [OT]"
		},
		{
			"name":"BCR family"
		},
		{
			"name":"BRD family [OT]"
		},
		{
			"name":"FAST family"
		},
		{
			"name":"G11 family"
		},
		{
			"name":"H11 family"
		},
		{
			"name":"PDHK family [OT]",
			"children":[
			{
				"name":"6561094 pyruvate dehydrogenase (acetyl-transferring) kinase, mitochondrial isoform X2\tK00898 PDK2_3_4; pyruvate dehydrogenase kinase 2\/3\/4 [EC:2.7.11.2]"
			}
			]
		},
		{
			"name":"PIKK family [OT]",
			"children":[
			{
				"name":"6569928 serine\/threonine-protein kinase ATM\tK04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]"
			},
			{
				"name":"6566559 serine\/threonine-protein kinase ATR\tK06640 ATR; serine\/threonine-protein kinase ATR [EC:2.7.11.1]"
			},
			{
				"name":"6562099 serine\/threonine-protein kinase Tor\tK07203 MTOR; serine\/threonine-protein kinase mTOR [EC:2.7.11.1]"
			},
			{
				"name":"6569502 serine\/threonine-protein kinase Smg1\tK08873 SMG1; serine\/threonine-protein kinase SMG1 [EC:2.7.11.1]"
			},
			{
				"name":"6560614 transcription-associated protein 1\tK08874 TRRAP; transformation\/transcription domain-associated protein"
			}
			]
		},
		{
			"name":"RIO family [OT]",
			"children":[
			{
				"name":"6558361 serine\/threonine-protein kinase RIO1\tK07178 RIOK1; RIO kinase 1 [EC:2.7.11.1]"
			},
			{
				"name":"6568320 serine\/threonine-protein kinase rio2\tK07179 RIOK2; RIO kinase 2 [EC:2.7.11.1]"
			},
			{
				"name":"6566639 serine\/threonine-protein kinase RIO3\tK08872 RIOK3; RIO kinase 3 [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"TAF1 family",
			"children":[
			{
				"name":"6563196 transcription initiation factor TFIID subunit 1 isoform X1\tK03125 TAF1; transcription initiation factor TFIID subunit 1 [EC:2.3.1.48 2.7.11.1]"
			}
			]
		},
		{
			"name":"TIF1 family [OT]",
			"children":[
			{
				"name":"6568593 transcription intermediary factor 1-alpha isoform X1\tK08883 TRIM33; tripartite motif-containing protein 33 [EC:2.3.2.27]"
			}
			]
		},
		{
			"name":"Other",
			"children":[
			{
				"name":"6568972 protein mahjong\tK11789 DCAF1; DDB1- and CUL4-associated factor 1 [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"Bacterial family"
		}
		]
	},
	{
		"name":"Receptor serine\/threonine kinases (RSTK): TKL group",
		"children":[
		{
			"name":"TGFBR1 family [OT]",
			"children":[
			{
				"name":"6559092 activin receptor type-1 isoform X1\tK04675 ACVR1; activin receptor type-1 [EC:2.7.11.30]"
			},
			{
				"name":"6566681 bone morphogenetic protein receptor type-1B isoform X1\tK13578 BMPR1B; bone morphogenetic protein receptor type-1B [EC:2.7.11.30]"
			},
			{
				"name":"6561166 TGF-beta receptor type-1 isoform X1\tK04674 TGFBR1; TGF-beta receptor type-1 [EC:2.7.11.30]"
			}
			]
		},
		{
			"name":"TGFBR2 family [OT]",
			"children":[
			{
				"name":"6569671 activin receptor type-2A\tK13596 ACVR2B; activin receptor type-2B [EC:2.7.11.30]"
			},
			{
				"name":"6570686 bone morphogenetic protein receptor type-2\tK04671 BMPR2; bone morphogenetic protein receptor type-2 [EC:2.7.11.30]"
			},
			{
				"name":"6566455 inhibin beta A chain\tK04669 TGFBRX; TGF-beta receptor, other"
			},
			{
				"name":"6570293 growth\/differentiation factor 8\tK04669 TGFBRX; TGF-beta receptor, other"
			}
			]
		}
		]
	},
	{
		"name":"Receptor tyrosine kinases (RTK)",
		"children":[
		{
			"name":"EGFR family [OT]",
			"children":[
			{
				"name":"6560193 epidermal growth factor receptor\tK04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]"
			}
			]
		},
		{
			"name":"INSR family [OT]",
			"children":[
			{
				"name":"6563200 insulin-like receptor isoform X1\tK05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]"
			},
			{
				"name":"6567180 atrial natriuretic peptide receptor 1\tK05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]"
			}
			]
		},
		{
			"name":"PDGFR family [OT]"
		},
		{
			"name":"FGFR family [OT]",
			"children":[
			{
				"name":"6564406 tyrosine kinase receptor Cad96Ca\tK04362 FGFR1; fibroblast growth factor receptor 1 [EC:2.7.10.1]"
			},
			{
				"name":"6568139 fibroblast growth factor receptor homolog 1\tK05094 FGFR3; fibroblast growth factor receptor 3 [EC:2.7.10.1]"
			}
			]
		},
		{
			"name":"VEGFR family [OT]",
			"children":[
			{
				"name":"6561707 platelet-derived growth factor receptor alpha isoform X1\tK05096 FLT1; FMS-like tyrosine kinase 1 [EC:2.7.10.1]"
			}
			]
		},
		{
			"name":"MET family"
		},
		{
			"name":"TRK family [OT]"
		},
		{
			"name":"EPH family [OT]",
			"children":[
			{
				"name":"6570312 ephrin type-B receptor 1-B\tK05110 EPHB1; Eph receptor B1 [EC:2.7.10.1]"
			}
			]
		},
		{
			"name":"AXL family"
		},
		{
			"name":"ALK family",
			"children":[
			{
				"name":"6569115 ALK tyrosine kinase receptor\tK05119 ALK; anaplastic lymphoma kinase [EC:2.7.10.1]"
			}
			]
		},
		{
			"name":"TIE family"
		},
		{
			"name":"ROR family",
			"children":[
			{
				"name":"6566956 tyrosine-protein kinase transmembrane receptor Ror isoform X1\tK05122 ROR1; receptor tyrosine kinase-like orphan receptor 1 [EC:2.7.10.1]"
			}
			]
		},
		{
			"name":"DDR family",
			"children":[
			{
				"name":"6562682 discoidin domain-containing receptor 2\tK05125 DDR2; discoidin domain receptor family member 2 [EC:2.7.10.1]"
			}
			]
		},
		{
			"name":"RET family",
			"children":[
			{
				"name":"6561746 uncharacterized protein LOC6561746\tK05126 RET; proto-oncogene tyrosine-protein kinase Ret [EC:2.7.10.1]"
			}
			]
		},
		{
			"name":"ROS family",
			"children":[
			{
				"name":"6569293 protein sevenless\tK05088 ROS1; proto-oncogene tyrosine-protein kinase ROS [EC:2.7.10.1]"
			}
			]
		},
		{
			"name":"CCK family",
			"children":[
			{
				"name":"6560223 tyrosine-protein kinase-like otk\tK05127 PTK7; PTK7 protein tyrosine kinase 7 [EC:2.7.10.1]"
			}
			]
		},
		{
			"name":"RYK family",
			"children":[
			{
				"name":"6561014 tyrosine-protein kinase RYK\tK05128 RYK; RYK receptor-like tyrosine kinase [EC:2.7.10.1]"
			},
			{
				"name":"6566848 tyrosine-protein kinase Dnt\tK05128 RYK; RYK receptor-like tyrosine kinase [EC:2.7.10.1]"
			},
			{
				"name":"6566852 tyrosine-protein kinase Drl\tK05128 RYK; RYK receptor-like tyrosine kinase [EC:2.7.10.1]"
			}
			]
		},
		{
			"name":"MUSK family",
			"children":[
			{
				"name":"6559740 tyrosine-protein kinase transmembrane receptor Ror2\tK05129 MUSK; muscle, skeletal, receptor tyrosine kinase [EC:2.7.10.1]"
			}
			]
		},
		{
			"name":"LMR family [OT]"
		}
		]
	},
	{
		"name":"Non-receptor tyrosine kinases",
		"children":[
		{
			"name":"ABL family",
			"children":[
			{
				"name":"6558858 tyrosine-protein kinase Abl isoform X4\tK06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]"
			}
			]
		},
		{
			"name":"ACK family",
			"children":[
			{
				"name":"6557190 uncharacterized protein LOC6557190\tK08886 TNK2; activated CDC42 kinase 1 [EC:2.7.10.2 2.7.11.1]"
			}
			]
		},
		{
			"name":"CSK family",
			"children":[
			{
				"name":"6563603 tyrosine-protein kinase CSK isoform X2\tK05728 CSK; C-terminal Src kinase [EC:2.7.10.4]"
			}
			]
		},
		{
			"name":"FAK family",
			"children":[
			{
				"name":"6560353 focal adhesion kinase 1 isoform X2\tK05725 PTK2; focal adhesion kinase 1 [EC:2.7.10.2]"
			}
			]
		},
		{
			"name":"FES family",
			"children":[
			{
				"name":"6563299 tyrosine-protein kinase Fer isoform X1\tK08889 FER; tyrosine-protein kinase Fer [EC:2.7.10.2]"
			}
			]
		},
		{
			"name":"JAK family [OT]",
			"children":[
			{
				"name":"6564516 tyrosine-protein kinase hopscotch\tK04447 JAK2; Janus kinase 2 [EC:2.7.10.2]"
			}
			]
		},
		{
			"name":"SRC family",
			"children":[
			{
				"name":"6560453 tyrosine-protein kinase Src42A isoform X5\tK08892 FRK; fyn-related kinase [EC:2.7.10.2]"
			},
			{
				"name":"6557856 tyrosine-protein kinase Src64B\tK05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]"
			}
			]
		},
		{
			"name":"TEC family",
			"children":[
			{
				"name":"6561963 tyrosine-protein kinase Btk29A isoform X1\tK07364 TEC; tyrosine-protein kinase Tec [EC:2.7.10.2]"
			}
			]
		},
		{
			"name":"SYK family",
			"children":[
			{
				"name":"6569019 tyrosine-protein kinase Shark\tK17512 SHARK; tyrosine-protein kinase shark [EC:2.7.10.2]"
			}
			]
		},
		{
			"name":"Other"
		},
		{
			"name":"Bacterial"
		}
		]
	},
	{
		"name":"Histidine kinases",
		"children":[
		{
			"name":"OmpR family"
		},
		{
			"name":"NarL family"
		},
		{
			"name":"Spo family [OT]"
		},
		{
			"name":"CitB family [OT]"
		},
		{
			"name":"LytTR family [OT]"
		},
		{
			"name":"NtrC family"
		},
		{
			"name":"CheA family [OT]"
		},
		{
			"name":"Cell cycle family [OT]"
		},
		{
			"name":"Lux family [OT]"
		},
		{
			"name":"LuxR family [OT]"
		},
		{
			"name":"Other"
		}
		]
	}
	]
}