{
	"name":"dhe03051",
	"children":[
	{
		"name":"Eukaryotic proteasome",
		"children":[
		{
			"name":"Core particles (20S proteasome)",
			"children":[
			{
				"name":"alpha type subunits",
				"children":[
				{
					"name":"111599909 proteasome subunit alpha type-6\tK02730 PSMA6; 20S proteasome subunit alpha 1 [EC:3.4.25.1]"
				},
				{
					"name":"111605297 proteasome subunit alpha type-6-like\tK02730 PSMA6; 20S proteasome subunit alpha 1 [EC:3.4.25.1]"
				},
				{
					"name":"111598832 proteasome subunit alpha type-2-like\tK02726 PSMA2; 20S proteasome subunit alpha 2 [EC:3.4.25.1]"
				},
				{
					"name":"111601478 proteasome subunit alpha type-2\tK02726 PSMA2; 20S proteasome subunit alpha 2 [EC:3.4.25.1]"
				},
				{
					"name":"111592490 proteasome subunit alpha type-4\tK02728 PSMA4; 20S proteasome subunit alpha 3 [EC:3.4.25.1]"
				},
				{
					"name":"111594318 proteasome subunit alpha type-7-1B\tK02731 PSMA7; 20S proteasome subunit alpha 4 [EC:3.4.25.1]"
				},
				{
					"name":"111594655 proteasome subunit alpha type-7-1B-like\tK02731 PSMA7; 20S proteasome subunit alpha 4 [EC:3.4.25.1]"
				},
				{
					"name":"111598837 proteasome subunit alpha type-7-1\tK02731 PSMA7; 20S proteasome subunit alpha 4 [EC:3.4.25.1]"
				},
				{
					"name":"111600580 proteasome subunit alpha type-5\tK02729 PSMA5; 20S proteasome subunit alpha 5 [EC:3.4.25.1]"
				},
				{
					"name":"111596303 proteasome subunit alpha type-1-like\tK02725 PSMA1; 20S proteasome subunit alpha 6 [EC:3.4.25.1]"
				},
				{
					"name":"111596646 proteasome subunit alpha type-1\tK02725 PSMA1; 20S proteasome subunit alpha 6 [EC:3.4.25.1]"
				},
				{
					"name":"111600023 proteasome subunit alpha type-3\tK02727 PSMA3; 20S proteasome subunit alpha 7 [EC:3.4.25.1]"
				}
				]
			},
			{
				"name":"beta type subunits",
				"children":[
				{
					"name":"111592110 proteasome subunit beta type-6-like\tK02738 PSMB6; 20S proteasome subunit beta 1 [EC:3.4.25.1]"
				},
				{
					"name":"111594012 proteasome subunit beta type-6\tK02738 PSMB6; 20S proteasome subunit beta 1 [EC:3.4.25.1]"
				},
				{
					"name":"111591885 proteasome subunit beta type-7\tK02739 PSMB7; 20S proteasome subunit beta 2 [EC:3.4.25.1]"
				},
				{
					"name":"111603707 proteasome subunit beta type-2-like isoform X1\tK02739 PSMB7; 20S proteasome subunit beta 2 [EC:3.4.25.1]"
				},
				{
					"name":"111604303 proteasome subunit beta type-7\tK02739 PSMB7; 20S proteasome subunit beta 2 [EC:3.4.25.1]"
				},
				{
					"name":"111604803 proteasome subunit beta type-3-like\tK02735 PSMB3; 20S proteasome subunit beta 3 [EC:3.4.25.1]"
				},
				{
					"name":"111604919 proteasome subunit beta type-3\tK02735 PSMB3; 20S proteasome subunit beta 3 [EC:3.4.25.1]"
				},
				{
					"name":"111596082 probable proteasome subunit beta type-2 isoform X1\tK02734 PSMB2; 20S proteasome subunit beta 4 [EC:3.4.25.1]"
				},
				{
					"name":"111596083 probable proteasome subunit beta type-2\tK02734 PSMB2; 20S proteasome subunit beta 4 [EC:3.4.25.1]"
				},
				{
					"name":"111602518 probable proteasome subunit beta type-2\tK02734 PSMB2; 20S proteasome subunit beta 4 [EC:3.4.25.1]"
				},
				{
					"name":"111592770 proteasome subunit beta type-5\tK02737 PSMB5; 20S proteasome subunit beta 5 [EC:3.4.25.1]"
				},
				{
					"name":"111600045 proteasome subunit beta type-5\tK02737 PSMB5; 20S proteasome subunit beta 5 [EC:3.4.25.1]"
				},
				{
					"name":"111592437 proteasome subunit beta type-1\tK02732 PSMB1; 20S proteasome subunit beta 6 [EC:3.4.25.1]"
				},
				{
					"name":"111598109 proteasome subunit beta type-1-like\tK02732 PSMB1; 20S proteasome subunit beta 6 [EC:3.4.25.1]"
				},
				{
					"name":"111604874 proteasome subunit beta type-4\tK02736 PSMB4; 20S proteasome subunit beta 7 [EC:3.4.25.1]"
				}
				]
			}
			]
		},
		{
			"name":"Regulatory particles",
			"children":[
			{
				"name":"PA700 (19S proteasome)",
				"children":[
				{
					"name":"ATPase subunits",
					"children":[
					{
						"name":"111604177 26S proteasome regulatory subunit 7\tK03061 PSMC2; 26S proteasome regulatory subunit T1"
					},
					{
						"name":"111598355 26S proteasome regulatory subunit 4\tK03062 PSMC1; 26S proteasome regulatory subunit T2"
					},
					{
						"name":"111598156 26S proteasome regulatory subunit 6B\tK03063 PSMC4; 26S proteasome regulatory subunit T3"
					},
					{
						"name":"111602793 26S proteasome regulatory subunit 6B\tK03063 PSMC4; 26S proteasome regulatory subunit T3"
					},
					{
						"name":"111597765 26S proteasome regulatory subunit 10B\tK03064 PSMC6; 26S proteasome regulatory subunit T4"
					},
					{
						"name":"111603539 26S proteasome regulatory subunit 10B\tK03064 PSMC6; 26S proteasome regulatory subunit T4"
					},
					{
						"name":"111602962 26S proteasome regulatory subunit 6A-B\tK03065 PSMC3; 26S proteasome regulatory subunit T5"
					},
					{
						"name":"115483798 LOW QUALITY PROTEIN: 26S proteasome regulatory subunit 6A-B-like\tK03065 PSMC3; 26S proteasome regulatory subunit T5"
					},
					{
						"name":"111597395 26S proteasome regulatory subunit 8\tK03066 PSMC5; 26S proteasome regulatory subunit T6"
					},
					{
						"name":"111598361 26S proteasome regulatory subunit 8\tK03066 PSMC5; 26S proteasome regulatory subunit T6"
					}
					]
				},
				{
					"name":"non-ATPase subunits",
					"children":[
					{
						"name":"111604435 26S proteasome non-ATPase regulatory subunit 2\tK03028 PSMD2; 26S proteasome regulatory subunit N1"
					},
					{
						"name":"111594542 26S proteasome non-ATPase regulatory subunit 1\tK03032 PSMD1; 26S proteasome regulatory subunit N2"
					},
					{
						"name":"111598969 probable 26S proteasome non-ATPase regulatory subunit 3\tK03033 PSMD3; 26S proteasome regulatory subunit N3"
					},
					{
						"name":"111605590 26S proteasome non-ATPase regulatory subunit 9\tK06693 PSMD9; 26S proteasome regulatory subunit N4"
					},
					{
						"name":"111600239 26S proteasome non-ATPase regulatory subunit 12\tK03035 PSMD12; 26S proteasome regulatory subunit N5"
					},
					{
						"name":"111601200 26S proteasome non-ATPase regulatory subunit 11 isoform X1\tK03036 PSMD11; 26S proteasome regulatory subunit N6"
					},
					{
						"name":"111600024 26S proteasome non-ATPase regulatory subunit 6\tK03037 PSMD6; 26S proteasome regulatory subunit N7"
					},
					{
						"name":"111599735 26S proteasome non-ATPase regulatory subunit 7\tK03038 PSMD7; 26S proteasome regulatory subunit N8"
					},
					{
						"name":"111602771 26S proteasome non-ATPase regulatory subunit 13\tK03039 PSMD13; 26S proteasome regulatory subunit N9"
					},
					{
						"name":"115483790 26S proteasome non-ATPase regulatory subunit 13-like\tK03039 PSMD13; 26S proteasome regulatory subunit N9"
					},
					{
						"name":"111605738 26S proteasome non-ATPase regulatory subunit 4\tK03029 PSMD4; 26S proteasome regulatory subunit N10"
					},
					{
						"name":"111599383 26S proteasome non-ATPase regulatory subunit 14\tK03030 PSMD14; 26S proteasome regulatory subunit N11"
					},
					{
						"name":"111597771 26S proteasome non-ATPase regulatory subunit 8\tK03031 PSMD8; 26S proteasome regulatory subunit N12"
					},
					{
						"name":"111604300 26S proteasome non-ATPase regulatory subunit 8\tK03031 PSMD8; 26S proteasome regulatory subunit N12"
					},
					{
						"name":"111592229 proteasomal ubiquitin receptor ADRM1 homolog isoform X1\tK06691 RPN13; 26S proteasome regulatory subunit N13"
					},
					{
						"name":"111595933 probable 26S proteasome complex subunit sem1\tK10881 SHFM1; 26 proteasome complex subunit DSS1"
					},
					{
						"name":"111602660 26S proteasome non-ATPase regulatory subunit 5\tK06692 PSMD5; 26S proteasome non-ATPase regulatory subunit 5"
					},
					{
						"name":"115482977 LOW QUALITY PROTEIN: 26S proteasome non-ATPase regulatory subunit 5-like\tK06692 PSMD5; 26S proteasome non-ATPase regulatory subunit 5"
					}
					]
				}
				]
			},
			{
				"name":"PA28 (11S REG)",
				"children":[
				{
					"name":"111602411 proteasome activator complex subunit 3\tK06698 PSME3; proteasome activator subunit 3 (PA28 gamma)"
				}
				]
			},
			{
				"name":"PA200"
			},
			{
				"name":"PI31",
				"children":[
				{
					"name":"111603111 proteasome inhibitor PI31 subunit-like\tK06700 PSMF1; proteasome inhibitor subunit 1 (PI31)"
				},
				{
					"name":"111603350 proteasome inhibitor PI31 subunit\tK06700 PSMF1; proteasome inhibitor subunit 1 (PI31)"
				}
				]
			}
			]
		},
		{
			"name":"Assembling factors",
			"children":[
			{
				"name":"Assembling chaperones",
				"children":[
				{
					"name":"111594947 proteasome maturation protein\tK11599 POMP; proteasome maturation protein"
				},
				{
					"name":"111599485 proteasome maturation protein-like\tK11599 POMP; proteasome maturation protein"
				},
				{
					"name":"111600259 uncharacterized protein LOC111600259\tK11875 PSMG1; proteasome assembly chaperone 1"
				},
				{
					"name":"111601375 proteasome assembly chaperone 2\tK11876 PSMG2; proteasome assembly chaperone 2"
				},
				{
					"name":"111603454 uncharacterized protein LOC111603454\tK11878 PSMG4; proteasome assembly chaperone 4"
				}
				]
			},
			{
				"name":"Other assembling factors",
				"children":[
				{
					"name":"111605659 eukaryotic translation initiation factor 3 subunit E\tK03250 EIF3E; translation initiation factor 3 subunit E"
				},
				{
					"name":"111593623 major heat shock 70 kDa protein Ba\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
				},
				{
					"name":"111594553 heat shock 70 kDa protein cognate 2\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
				},
				{
					"name":"111596498 heat shock protein 68-like\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
				},
				{
					"name":"111601646 major heat shock 70 kDa protein Ba-like\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
				},
				{
					"name":"111603010 heat shock 70 kDa protein cognate 4\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
				},
				{
					"name":"111604194 heat shock protein 68\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
				},
				{
					"name":"111604413 heat shock 70 kDa protein cognate 1\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
				},
				{
					"name":"115482793 major heat shock 70 kDa protein Ba\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
				},
				{
					"name":"111598466 heat shock protein 83\tK04079 HSP90A; molecular chaperone HtpG"
				},
				{
					"name":"111596161 RNA-binding protein NOB1\tK11883 NOB1; RNA-binding protein NOB1"
				},
				{
					"name":"111593473 RNA-binding protein pno1\tK11884 PNO1; RNA-binding protein PNO1"
				}
				]
			}
			]
		},
		{
			"name":"Proteasome interacting proteins (PIPs)",
			"children":[
			{
				"name":"UBL-UBA shuttle proteins",
				"children":[
				{
					"name":"111593709 UV excision repair protein RAD23 homolog B\tK10839 RAD23; UV excision repair protein RAD23"
				},
				{
					"name":"111593422 ubiquilin-1\tK04523 UBQLN; ubiquilin"
				},
				{
					"name":"111605595 ubiquilin-1\tK04523 UBQLN; ubiquilin"
				},
				{
					"name":"111596774 protein DDI1 homolog 2\tK11885 DDI; DNA damage-inducible protein [EC:3.4.23.-]"
				},
				{
					"name":"111596866 NEDD8 ultimate buster 1\tK29014 NUB1; NEDD8 ultimate buster 1"
				},
				{
					"name":"111602937 NEDD8 ultimate buster 1\tK29014 NUB1; NEDD8 ultimate buster 1"
				}
				]
			},
			{
				"name":"Other PIPs",
				"children":[
				{
					"name":"111597925 proteasome-associated protein ECM29 homolog\tK11886 ECM29; proteasome component ECM29"
				},
				{
					"name":"111597054 JNK1\/MAPK8-associated membrane protein\tK28966 JKAMP; JNK1\/MAPK8-associated membrane protein"
				},
				{
					"name":"111595984 midnolin homolog\tK29091 MIDN; midnolin"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic proteasome",
		"children":[
		{
			"name":"Core particles (20S proteasome)"
		},
		{
			"name":"Bacterial regulatory particles"
		},
		{
			"name":"Archaeal regulatory particles"
		}
		]
	}
	]
}