{
	"name":"dpol03400",
	"children":[
	{
		"name":"Eukaryotic type",
		"children":[
		{
			"name":"SSBR (single strand breaks repair)",
			"children":[
			{
				"name":"Direct repair",
				"children":[
				{
					"name":"127865737 methylated-DNA--protein-cysteine methyltransferase-like isoform X1\tK00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]"
				},
				{
					"name":"127847997 DNA oxidative demethylase ALKBH2-like\tK10859 ALKBH2; DNA oxidative demethylase [EC:1.14.11.33]"
				},
				{
					"name":"127850163 DNA oxidative demethylase ALKBH2-like\tK10859 ALKBH2; DNA oxidative demethylase [EC:1.14.11.33]"
				},
				{
					"name":"127852137 alpha-ketoglutarate-dependent dioxygenase alkB homolog 3-like\tK10860 ALKBH3; mRNA N1-methyladenine demethylase [EC:1.14.11.54]"
				},
				{
					"name":"127852533 activating signal cointegrator 1 complex subunit 3-like\tK18663 ASCC3; activating signal cointegrator complex subunit 3 [EC:5.6.2.4]"
				},
				{
					"name":"127853552 LOW QUALITY PROTEIN: activating signal cointegrator 1 complex subunit 3-like\tK18663 ASCC3; activating signal cointegrator complex subunit 3 [EC:5.6.2.4]"
				},
				{
					"name":"127834725 deoxyribodipyrimidine photo-lyase-like isoform X1\tK01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]"
				}
				]
			},
			{
				"name":"BER (base exicision repair)",
				"children":[
				{
					"name":"DNA glycosylases",
					"children":[
					{
						"name":"127841570 uracil-DNA glycosylase-like isoform X1\tK03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]"
					},
					{
						"name":"127855837 uracil-DNA glycosylase-like\tK03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]"
					},
					{
						"name":"127855838 uracil-DNA glycosylase-like\tK03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]"
					},
					{
						"name":"127865786 uncharacterized protein LOC127865786 isoform X1\tK03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]"
					},
					{
						"name":"127838751 N-glycosylase\/DNA lyase-like\tK03660 OGG1; N-glycosylase\/DNA lyase [EC:3.2.2.- 4.2.99.18]"
					},
					{
						"name":"127879742 endonuclease 8-like 1\tK10567 NEIL1; endonuclease VIII-like 1 [EC:3.2.2.- 4.2.99.18]"
					},
					{
						"name":"127854528 endonuclease 8-like 3\tK10569 NEIL3; endonuclease VIII-like 3 [EC:3.2.2.- 4.2.99.18]"
					},
					{
						"name":"127872003 LOW QUALITY PROTEIN: endonuclease 8-like 3\tK10569 NEIL3; endonuclease VIII-like 3 [EC:3.2.2.- 4.2.99.18]"
					},
					{
						"name":"127877185 endonuclease 8-like 3\tK10569 NEIL3; endonuclease VIII-like 3 [EC:3.2.2.- 4.2.99.18]"
					}
					]
				},
				{
					"name":"AP endonucleases",
					"children":[
					{
						"name":"127850388 exodeoxyribonuclease-like isoform X1\tK10771 APEX1; AP endonuclease 1 [EC:3.1.11.2]"
					},
					{
						"name":"127881165 DNA-(apurinic or apyrimidinic site) endonuclease 2-like\tK10772 APEX2; AP endonuclease 2 [EC:3.1.11.2]"
					},
					{
						"name":"127881508 DNA-(apurinic or apyrimidinic site) endonuclease 2-like isoform X1\tK10772 APEX2; AP endonuclease 2 [EC:3.1.11.2]"
					}
					]
				},
				{
					"name":"Long Patch-BER factors",
					"children":[
					{
						"name":"DNA polymerase delta complex",
						"children":[
						{
							"name":"127840856 DNA polymerase delta catalytic subunit-like\tK02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]"
						},
						{
							"name":"127866459 DNA polymerase delta subunit 2-like isoform X1\tK02328 POLD2; DNA polymerase delta subunit 2"
						},
						{
							"name":"127833806 DNA polymerase delta subunit 3-like isoform X1\tK03504 POLD3; DNA polymerase delta subunit 3"
						}
						]
					},
					{
						"name":"DNA polymerase epsilon complex",
						"children":[
						{
							"name":"127860117 DNA polymerase epsilon catalytic subunit A-like\tK02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]"
						},
						{
							"name":"127860129 DNA polymerase epsilon catalytic subunit A-like\tK02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]"
						},
						{
							"name":"127832647 DNA polymerase epsilon subunit 2-like\tK02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]"
						},
						{
							"name":"127837271 DNA polymerase epsilon subunit 3-like\tK02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]"
						}
						]
					},
					{
						"name":"127866723 proliferating cell nuclear antigen-like\tK04802 PCNA; proliferating cell nuclear antigen"
					},
					{
						"name":"127846533 flap endonuclease 1-like\tK04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]"
					},
					{
						"name":"127866131 DNA ligase 1-like isoform X1\tK10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]"
					}
					]
				},
				{
					"name":"Short Patch-BER factors",
					"children":[
					{
						"name":"127867389 DNA polymerase beta-like isoform X1\tK02330 POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-]"
					},
					{
						"name":"127871494 DNA repair protein XRCC1-like isoform X1\tK10803 XRCC1; DNA-repair protein XRCC1"
					},
					{
						"name":"127850523 DNA ligase 3-like isoform X1\tK10776 LIG3; DNA ligase 3 [EC:6.5.1.1]"
					}
					]
				},
				{
					"name":"Other BER factors",
					"children":[
					{
						"name":"127870863 tyrosyl-DNA phosphodiesterase 1-like isoform X1\tK10862 TDP1; tyrosyl-DNA phosphodiesterase 1 [EC:3.1.4.-]"
					},
					{
						"name":"127836357 aprataxin-like\tK10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]"
					},
					{
						"name":"127841195 uncharacterized protein F21D5.5-like isoform X1\tK08073 PNKP; bifunctional polynucleotide phosphatase\/kinase [EC:3.1.3.32 2.7.1.78]"
					},
					{
						"name":"127882380 bifunctional polynucleotide phosphatase\/kinase-like\tK08073 PNKP; bifunctional polynucleotide phosphatase\/kinase [EC:3.1.3.32 2.7.1.78]"
					},
					{
						"name":"127880203 high mobility group protein B1-like\tK10802 HMGB1; high mobility group protein B1"
					},
					{
						"name":"127839443 DNA polymerase lambda-like\tK03512 POLL; DNA polymerase lambda [EC:2.7.7.7 4.2.99.-]"
					},
					{
						"name":"127872822 poly [ADP-ribose] polymerase 1-like\tK24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30]"
					},
					{
						"name":"127844148 poly [ADP-ribose] polymerase 2-like\tK28005 PARP2; poly [ADP-ribose] polymerase 2 [EC:2.4.2.30]"
					},
					{
						"name":"127844571 poly [ADP-ribose] polymerase 2-like\tK28005 PARP2; poly [ADP-ribose] polymerase 2 [EC:2.4.2.30]"
					},
					{
						"name":"127851394 uncharacterized protein LOC127851394 isoform X1\tK10798 PARP3_4; protein mono-ADP-ribosyltransferase 3\/4 [EC:2.4.2.-]"
					},
					{
						"name":"127880663 protein mono-ADP-ribosyltransferase PARP3-like\tK10798 PARP3_4; protein mono-ADP-ribosyltransferase 3\/4 [EC:2.4.2.-]"
					}
					]
				}
				]
			},
			{
				"name":"NER (nucleotide excision repair)",
				"children":[
				{
					"name":"GGR (global genome repair) factors",
					"children":[
					{
						"name":"XPC-HR23B-CETN2 complex",
						"children":[
						{
							"name":"127862156 UV excision repair protein RAD23 homolog B-like isoform X1\tK10839 RAD23; UV excision repair protein RAD23"
						},
						{
							"name":"127862157 UV excision repair protein RAD23 homolog B-like\tK10839 RAD23; UV excision repair protein RAD23"
						},
						{
							"name":"127877788 uncharacterized protein LOC127877788\tK10840 CETN2; centrin-2"
						},
						{
							"name":"127878308 uncharacterized protein LOC127878308\tK10840 CETN2; centrin-2"
						},
						{
							"name":"127880972 uncharacterized protein LOC127880972\tK10840 CETN2; centrin-2"
						}
						]
					},
					{
						"name":"Cul4-DDB2 complex",
						"children":[
						{
							"name":"127842647 E3 ubiquitin-protein ligase RBX1\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
						},
						{
							"name":"127833976 cullin-4A-like isoform X1\tK10609 CUL4; cullin 4"
						},
						{
							"name":"127834212 cullin-4A-like\tK10609 CUL4; cullin 4"
						},
						{
							"name":"127831978 DNA damage-binding protein 1-like isoform X1\tK10610 DDB1; DNA damage-binding protein 1"
						},
						{
							"name":"127832055 DNA damage-binding protein 2-like\tK10140 DDB2; DNA damage-binding protein 2"
						},
						{
							"name":"127832056 DNA damage-binding protein 2-like\tK10140 DDB2; DNA damage-binding protein 2"
						}
						]
					},
					{
						"name":"NER4 complex"
					}
					]
				},
				{
					"name":"TCR (transcription coupled repair) factors",
					"children":[
					{
						"name":"DNA-directed RNA polymerase II complex",
						"children":[
						{
							"name":"127833765 DNA-directed RNA polymerase II subunit RPB1-like\tK03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]"
						},
						{
							"name":"127834155 LOW QUALITY PROTEIN: DNA-directed RNA polymerase II subunit RPB1-like\tK03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]"
						},
						{
							"name":"127836141 DNA-directed RNA polymerase II subunit RPB1-like\tK03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]"
						},
						{
							"name":"127840835 DNA-directed RNA polymerase II subunit RPB2 isoform X1\tK03010 RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]"
						},
						{
							"name":"127843611 DNA-directed RNA polymerase II subunit RPB3-like\tK03011 RPB3; DNA-directed RNA polymerase II subunit RPB3"
						},
						{
							"name":"127844923 DNA-directed RNA polymerase II subunit RPB3-like isoform X1\tK03011 RPB3; DNA-directed RNA polymerase II subunit RPB3"
						},
						{
							"name":"127831753 uncharacterized protein LOC127831753 isoform X1\tK03012 RPB4; DNA-directed RNA polymerase II subunit RPB4"
						},
						{
							"name":"127855280 DNA-directed RNA polymerases I, II, and III subunit RPABC1 isoform X1\tK03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1"
						},
						{
							"name":"127849594 DNA-directed RNA polymerases I, II, and III subunit RPABC2-like\tK03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2"
						},
						{
							"name":"127867826 DNA-directed RNA polymerase II subunit RPB7\tK03015 RPB7; DNA-directed RNA polymerase II subunit RPB7"
						},
						{
							"name":"127863357 DNA-directed RNA polymerases I, II, and III subunit RPABC3-like isoform X1\tK03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3"
						},
						{
							"name":"127873206 DNA-directed RNA polymerase II subunit RPB9-like\tK03017 RPB9; DNA-directed RNA polymerase II subunit RPB9"
						},
						{
							"name":"127841010 DNA-directed RNA polymerase II subunit RPB11-a-like\tK03008 RPB11; DNA-directed RNA polymerase II subunit RPB11"
						},
						{
							"name":"127841019 DNA-directed RNA polymerase II subunit RPB11-a-like\tK03008 RPB11; DNA-directed RNA polymerase II subunit RPB11"
						},
						{
							"name":"127857738 DNA-directed RNA polymerases I, II, and III subunit RPABC4-like\tK03009 RPABC4; DNA-directed RNA polymerases I, II, and III subunit RPABC4"
						}
						]
					},
					{
						"name":"Cul4-CSA complex",
						"children":[
						{
							"name":"127842647 E3 ubiquitin-protein ligase RBX1\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
						},
						{
							"name":"127833976 cullin-4A-like isoform X1\tK10609 CUL4; cullin 4"
						},
						{
							"name":"127834212 cullin-4A-like\tK10609 CUL4; cullin 4"
						},
						{
							"name":"127831978 DNA damage-binding protein 1-like isoform X1\tK10610 DDB1; DNA damage-binding protein 1"
						},
						{
							"name":"127867512 DNA excision repair protein ERCC-8-like isoform X1\tK10570 ERCC8; DNA excision repair protein ERCC-8"
						}
						]
					},
					{
						"name":"Other TCR factor",
						"children":[
						{
							"name":"127868634 DNA excision repair protein ERCC-6-like\tK10841 ERCC6; DNA excision repair protein ERCC-6"
						},
						{
							"name":"127840528 UV-stimulated scaffold protein A-like\tK23720 UVSSA; UV-stimulated scaffold protein A"
						},
						{
							"name":"127840815 UV-stimulated scaffold protein A-like\tK23720 UVSSA; UV-stimulated scaffold protein A"
						}
						]
					}
					]
				},
				{
					"name":"TFIIH complex",
					"children":[
					{
						"name":"127855041 general transcription and DNA repair factor IIH helicase subunit XPB-like isoform X1\tK10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]"
					},
					{
						"name":"127871313 general transcription and DNA repair factor IIH helicase subunit XPD-like\tK10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]"
					},
					{
						"name":"127870608 general transcription factor IIH subunit 1-like\tK03141 TFIIH1; transcription initiation factor TFIIH subunit 1"
					},
					{
						"name":"127882075 LOW QUALITY PROTEIN: general transcription factor IIH subunit 2-like\tK03142 TFIIH2; transcription initiation factor TFIIH subunit 2"
					},
					{
						"name":"127871454 general transcription factor IIH subunit 3-like isoform X1\tK03143 TFIIH3; transcription initiation factor TFIIH subunit 3"
					},
					{
						"name":"127837076 general transcription factor IIH subunit 4-like isoform X1\tK03144 TFIIH4; transcription initiation factor TFIIH subunit 4"
					},
					{
						"name":"127838181 general transcription factor IIH subunit 4-like isoform X1\tK03144 TFIIH4; transcription initiation factor TFIIH subunit 4"
					},
					{
						"name":"127880297 cyclin-dependent kinase 7-like\tK02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]"
					},
					{
						"name":"127854591 cyclin-H-like\tK06634 CCNH; cyclin H"
					},
					{
						"name":"127875409 CDK-activating kinase assembly factor MAT1-like\tK10842 MNAT1; CDK-activating kinase assembly factor MAT1"
					}
					]
				},
				{
					"name":"RPA (replication factor A)",
					"children":[
					{
						"name":"127871431 replication protein A 70 kDa DNA-binding subunit-like\tK07466 RFA1; replication factor A1"
					},
					{
						"name":"127855276 replication protein A 32 kDa subunit-like\tK10739 RFA2; replication factor A2"
					},
					{
						"name":"127840097 replication protein A 14 kDa subunit-like\tK10740 RPA3; replication factor A3"
					}
					]
				},
				{
					"name":"Other NER factors",
					"children":[
					{
						"name":"127879360 DNA repair protein complementing XP-A cells homolog\tK10847 XPA; DNA-repair protein complementing XP-A cells"
					},
					{
						"name":"127868569 DNA excision repair protein ERCC-1-like isoform X1\tK10849 ERCC1; DNA excision repair protein ERCC-1"
					},
					{
						"name":"127861879 DNA repair endonuclease XPF-like\tK10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]"
					},
					{
						"name":"127862128 DNA repair endonuclease XPF-like isoform X1\tK10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]"
					},
					{
						"name":"127866131 DNA ligase 1-like isoform X1\tK10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]"
					},
					{
						"name":"127857506 MMS19 nucleotide excision repair protein homolog isoform X1\tK15075 MET18; DNA repair\/transcription protein MET18\/MMS19"
					},
					{
						"name":"127861015 probable cytosolic iron-sulfur protein assembly protein CIAO1 homolog\tK24730 CIAO1; cytosolic iron-sulfur protein assembly protein CIAO1"
					},
					{
						"name":"127844554 cytosolic iron-sulfur assembly component 2B-like\tK26403 CIAO2; cytosolic iron-sulfur assembly component 2"
					},
					{
						"name":"127834124 cullin-3-like\tK03869 CUL3; cullin 3"
					},
					{
						"name":"127850446 cullin-5-like\tK10612 CUL5; cullin 5"
					},
					{
						"name":"127861506 elongin-C isoform X1\tK03872 ELOC; elongin-C"
					},
					{
						"name":"127846722 elongin-B-like\tK03873 ELOB; elongin-B"
					},
					{
						"name":"127876934 protein lingerer-like isoform X1\tK26545 UBAP2; ubiquitin-associated protein 2"
					}
					]
				}
				]
			},
			{
				"name":"MMR (mismatch excision repair)",
				"children":[
				{
					"name":"Mismatch and loop recognition factors",
					"children":[
					{
						"name":"127852333 DNA mismatch repair protein Msh2-like\tK08735 MSH2; DNA mismatch repair protein MSH2"
					},
					{
						"name":"127879013 DNA mismatch repair protein Msh3-like isoform X1\tK08736 MSH3; DNA mismatch repair protein MSH3"
					},
					{
						"name":"127857841 DNA mismatch repair protein Msh6-like\tK08737 MSH6; DNA mismatch repair protein MSH6"
					}
					]
				},
				{
					"name":"MutL homologs",
					"children":[
					{
						"name":"127856468 DNA mismatch repair protein Mlh1-like\tK08734 MLH1; DNA mismatch repair protein MLH1"
					}
					]
				},
				{
					"name":"DNA polymerase delta complex",
					"children":[
					{
						"name":"127840856 DNA polymerase delta catalytic subunit-like\tK02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]"
					},
					{
						"name":"127866459 DNA polymerase delta subunit 2-like isoform X1\tK02328 POLD2; DNA polymerase delta subunit 2"
					},
					{
						"name":"127833806 DNA polymerase delta subunit 3-like isoform X1\tK03504 POLD3; DNA polymerase delta subunit 3"
					}
					]
				},
				{
					"name":"RPA (replication factor A)",
					"children":[
					{
						"name":"127871431 replication protein A 70 kDa DNA-binding subunit-like\tK07466 RFA1; replication factor A1"
					},
					{
						"name":"127855276 replication protein A 32 kDa subunit-like\tK10739 RFA2; replication factor A2"
					},
					{
						"name":"127840097 replication protein A 14 kDa subunit-like\tK10740 RPA3; replication factor A3"
					}
					]
				},
				{
					"name":"RFC (replication factor C)",
					"children":[
					{
						"name":"127871969 replication factor C subunit 1-like\tK10754 RFC1; replication factor C subunit 1"
					},
					{
						"name":"127872691 LOW QUALITY PROTEIN: replication factor C subunit 1-like\tK10754 RFC1; replication factor C subunit 1"
					},
					{
						"name":"127834234 replication factor C subunit 4-like\tK10755 RFC2_4; replication factor C subunit 2\/4"
					},
					{
						"name":"127834385 replication factor C subunit 4-like\tK10755 RFC2_4; replication factor C subunit 2\/4"
					},
					{
						"name":"127871442 replication factor C subunit 2-like isoform X1\tK10755 RFC2_4; replication factor C subunit 2\/4"
					},
					{
						"name":"127834383 replication factor C subunit 5-like\tK10756 RFC3_5; replication factor C subunit 3\/5"
					},
					{
						"name":"127877752 replication factor C subunit 3-like\tK10756 RFC3_5; replication factor C subunit 3\/5"
					}
					]
				},
				{
					"name":"Other MMR factors",
					"children":[
					{
						"name":"127866723 proliferating cell nuclear antigen-like\tK04802 PCNA; proliferating cell nuclear antigen"
					},
					{
						"name":"127880203 high mobility group protein B1-like\tK10802 HMGB1; high mobility group protein B1"
					},
					{
						"name":"127866131 DNA ligase 1-like isoform X1\tK10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]"
					},
					{
						"name":"127868343 WD repeat-containing protein 76-like isoform X1\tK24755 WDR76; WD repeat-containing protein 76"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"DSBR (double strand breaks repair)",
			"children":[
			{
				"name":"HR (homologous recombination)",
				"children":[
				{
					"name":"MRN(MRX) complex",
					"children":[
					{
						"name":"127867645 double-strand break repair protein MRE11-like isoform X1\tK10865 MRE11; double-strand break repair protein MRE11"
					},
					{
						"name":"127877166 DNA repair protein RAD50-like\tK10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]"
					},
					{
						"name":"127843977 nibrin-like isoform X1\tK10867 NBN; nibrin"
					},
					{
						"name":"127843978 nibrin-like isoform X1\tK10867 NBN; nibrin"
					}
					]
				},
				{
					"name":"BRCA1-core complex",
					"children":[
					{
						"name":"127854987 BRCA1-associated RING domain protein 1-like\tK10683 BARD1; BRCA1-associated RING domain protein 1"
					}
					]
				},
				{
					"name":"BRCA1-A complex",
					"children":[
					{
						"name":"127861397 BRISC and BRCA1-A complex member 1-like\tK20776 BABAM; BRISC and BRCA1-A complex member 1"
					},
					{
						"name":"127872909 BRISC and BRCA1-A complex member 2-like isoform X1\tK12173 BRE; BRCA1-A complex subunit BRE"
					},
					{
						"name":"127868011 lys-63-specific deubiquitinase BRCC36-like\tK11864 BRCC3; BRCA1\/BRCA2-containing complex subunit 3 [EC:3.4.19.-]"
					},
					{
						"name":"127868075 lys-63-specific deubiquitinase BRCC36-like\tK11864 BRCC3; BRCA1\/BRCA2-containing complex subunit 3 [EC:3.4.19.-]"
					}
					]
				},
				{
					"name":"BRCA1-B complex"
				},
				{
					"name":"BRCA1-C complex",
					"children":[
					{
						"name":"127857683 uncharacterized protein LOC127857683\tK20773 RBBP8; DNA endonuclease RBBP8 [EC:3.1.-.-]"
					},
					{
						"name":"127867645 double-strand break repair protein MRE11-like isoform X1\tK10865 MRE11; double-strand break repair protein MRE11"
					},
					{
						"name":"127877166 DNA repair protein RAD50-like\tK10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]"
					},
					{
						"name":"127843977 nibrin-like isoform X1\tK10867 NBN; nibrin"
					},
					{
						"name":"127843978 nibrin-like isoform X1\tK10867 NBN; nibrin"
					}
					]
				},
				{
					"name":"BRCA complex",
					"children":[
					{
						"name":"127876253 breast cancer type 2 susceptibility protein homolog isoform X1\tK08775 BRCA2; breast cancer 2 susceptibility protein"
					},
					{
						"name":"127857615 DNA repair protein RAD51 homolog 1\tK04482 RAD51; DNA repair protein RAD51"
					}
					]
				},
				{
					"name":"RecA family proteins",
					"children":[
					{
						"name":"127857615 DNA repair protein RAD51 homolog 1\tK04482 RAD51; DNA repair protein RAD51"
					},
					{
						"name":"127871932 DNA repair protein RAD51 homolog 3-like\tK10870 RAD51L2; RAD51-like protein 2"
					},
					{
						"name":"127834380 DNA repair protein RAD51 homolog 4-like\tK10871 RAD51L3; RAD51-like protein 3"
					},
					{
						"name":"127837532 DNA repair protein XRCC2-like isoform X1\tK10879 XRCC2; DNA-repair protein XRCC2"
					},
					{
						"name":"127872174 DNA repair protein XRCC3-like\tK10880 XRCC3; DNA-repair protein XRCC3"
					},
					{
						"name":"127874751 DNA repair protein XRCC3-like\tK10880 XRCC3; DNA-repair protein XRCC3"
					}
					]
				},
				{
					"name":"Rad52 family proteins",
					"children":[
					{
						"name":"127858210 RAD52 motif-containing protein 1-like isoform X1\tK10874 RDM1; RAD52 motif-containing protein 1"
					}
					]
				},
				{
					"name":"Rad54 family proteins",
					"children":[
					{
						"name":"127862914 DNA repair and recombination protein RAD54-like\tK10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]"
					},
					{
						"name":"127832552 helicase ARIP4-like isoform X1\tK10876 RAD54L2; RAD54-like protein 2 [EC:5.6.2.-]"
					},
					{
						"name":"127881594 helicase ARIP4-like\tK10876 RAD54L2; RAD54-like protein 2 [EC:5.6.2.-]"
					},
					{
						"name":"127866365 DNA repair and recombination protein RAD54B-like\tK10877 RAD54B; DNA repair and recombination protein RAD54B [EC:5.6.2.-]"
					}
					]
				},
				{
					"name":"RecQ family DNA helicases",
					"children":[
					{
						"name":"127834484 uncharacterized protein LOC127834484 isoform X1\tK10899 RECQL; ATP-dependent DNA helicase Q1 [EC:5.6.2.4]"
					},
					{
						"name":"127840843 putative ATP-dependent DNA helicase Q1\tK10899 RECQL; ATP-dependent DNA helicase Q1 [EC:5.6.2.4]"
					},
					{
						"name":"127853625 putative ATP-dependent DNA helicase Q1\tK10899 RECQL; ATP-dependent DNA helicase Q1 [EC:5.6.2.4]"
					},
					{
						"name":"127871409 ATP-dependent DNA helicase Q1-like isoform X1\tK10899 RECQL; ATP-dependent DNA helicase Q1 [EC:5.6.2.4]"
					},
					{
						"name":"127878161 putative ATP-dependent DNA helicase Q1 isoform X1\tK10899 RECQL; ATP-dependent DNA helicase Q1 [EC:5.6.2.4]"
					},
					{
						"name":"127880854 ATP-dependent DNA helicase RecQ-like\tK10899 RECQL; ATP-dependent DNA helicase Q1 [EC:5.6.2.4]"
					},
					{
						"name":"127861409 bifunctional 3'-5' exonuclease\/ATP-dependent helicase WRN-like isoform X1\tK10900 WRN; werner syndrome ATP-dependent helicase [EC:5.6.2.4]"
					},
					{
						"name":"127879413 ATP-dependent DNA helicase Q5-like isoform X1\tK10902 RECQL5; ATP-dependent DNA helicase Q5 [EC:5.6.2.4]"
					}
					]
				},
				{
					"name":"Bloom's syndrome complex (BTR)",
					"children":[
					{
						"name":"127847317 DNA topoisomerase 3-beta-1-like\tK03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]"
					},
					{
						"name":"127867203 DNA topoisomerase 3-alpha-like isoform X1\tK03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]"
					},
					{
						"name":"127869762 DNA topoisomerase 3-alpha-like\tK03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]"
					},
					{
						"name":"127861652 uncharacterized protein LOC127861652\tK15365 RMI2; RecQ-mediated genome instability protein 2"
					},
					{
						"name":"127861653 uncharacterized protein LOC127861653 isoform X1\tK15365 RMI2; RecQ-mediated genome instability protein 2"
					},
					{
						"name":"127861655 uncharacterized protein LOC127861655\tK15365 RMI2; RecQ-mediated genome instability protein 2"
					}
					]
				},
				{
					"name":"RPA (replication factor A)",
					"children":[
					{
						"name":"127871431 replication protein A 70 kDa DNA-binding subunit-like\tK07466 RFA1; replication factor A1"
					},
					{
						"name":"127855276 replication protein A 32 kDa subunit-like\tK10739 RFA2; replication factor A2"
					},
					{
						"name":"127840097 replication protein A 14 kDa subunit-like\tK10740 RPA3; replication factor A3"
					}
					]
				},
				{
					"name":"Protein phosphatase 4",
					"children":[
					{
						"name":"127853244 serine\/threonine-protein phosphatase 4 catalytic subunit\tK15423 PPP4C; serine\/threonine-protein phosphatase 4 catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"127874716 serine\/threonine-protein phosphatase 4 regulatory subunit 3A-like isoform X1\tK17491 SMEK; protein phosphatase 4 regulatory subunit 3"
					},
					{
						"name":"127875075 LOW QUALITY PROTEIN: serine\/threonine-protein phosphatase 4 regulatory subunit 4-like\tK15426 PPP4R4; serine\/threonine-protein phosphatase 4 regulatory subunit 4"
					}
					]
				},
				{
					"name":"AP-5 complex",
					"children":[
					{
						"name":"127877681 AP-5 complex subunit beta-1-like isoform X1\tK19022 AP5B1; AP-5 complex subunit beta-1"
					},
					{
						"name":"127857991 AP-5 complex subunit mu-1-like isoform X1\tK19023 AP5M1; AP-5 complex subunit mu-1"
					},
					{
						"name":"127842271 AP-5 complex subunit sigma-1-like\tK19024 AP5S1; AP-5 complex subunit sigma-1"
					}
					]
				},
				{
					"name":"SMC5-SMC6 complex",
					"children":[
					{
						"name":"127875946 structural maintenance of chromosomes protein 5-like\tK22803 SMC5; structural maintenance of chromosomes protein 5"
					},
					{
						"name":"127861429 structural maintenance of chromosomes protein 6-like isoform X1\tK22804 SMC6; structural maintenance of chromosomes protein 6"
					},
					{
						"name":"127862772 non-structural maintenance of chromosomes element 1 homolog isoform X1\tK22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27]"
					},
					{
						"name":"127862789 non-structural maintenance of chromosomes element 1 homolog isoform X1\tK22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27]"
					},
					{
						"name":"127880532 E3 SUMO-protein ligase NSE2-like\tK22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]"
					},
					{
						"name":"127880729 E3 SUMO-protein ligase NSE2-like\tK22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]"
					},
					{
						"name":"127880730 E3 SUMO-protein ligase NSE2-like\tK22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]"
					},
					{
						"name":"127841834 non-structural maintenance of chromosomes element 3 homolog isoform X1\tK22823 NSMCE3; non-structural maintenance of chromosomes element 3"
					},
					{
						"name":"127871094 EP300-interacting inhibitor of differentiation 3-like\tK22825 NSMCE4; non-structural maintenance of chromosomes element 4"
					}
					]
				},
				{
					"name":"Other HR factors",
					"children":[
					{
						"name":"127866856 crossover junction endonuclease EME1-like\tK10882 EME1; crossover junction endonuclease EME1 [EC:3.1.22.-]"
					},
					{
						"name":"127857899 exonuclease 3'-5' domain-containing protein 2-like isoform X1\tK20777 EXD2; exonuclease 3'-5' domain-containing protein 2 [EC:3.1.11.1]"
					},
					{
						"name":"127854304 26S proteasome complex subunit SEM1-like\tK10881 SHFM1; 26 proteasome complex subunit DSS1"
					},
					{
						"name":"127840123 DNA repair protein SWI5 homolog isoform X1\tK10991 SWI5; DNA repair protein Swi5\/Sae3"
					},
					{
						"name":"127853367 structure-specific endonuclease subunit slx1-like isoform X1\tK15078 SLX1; structure-specific endonuclease subunit SLX1 [EC:3.6.1.-]"
					},
					{
						"name":"127852232 spatacsin-like isoform X1\tK19026 SPG11; spatacsin"
					},
					{
						"name":"127852233 spatacsin-like\tK19026 SPG11; spatacsin"
					},
					{
						"name":"127855764 mortality factor 4-like protein 1\tK11339 MORF4L1; mortality factor 4-like protein 1"
					},
					{
						"name":"127844463 deoxynucleoside triphosphate triphosphohydrolase SAMHD1-like isoform X1\tK22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-]"
					},
					{
						"name":"127845419 deoxynucleoside triphosphate triphosphohydrolase SAMHD1-like\tK22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-]"
					},
					{
						"name":"127845909 deoxynucleoside triphosphate triphosphohydrolase SAMHD1-like\tK22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-]"
					},
					{
						"name":"127846364 deoxynucleoside triphosphate triphosphohydrolase SAMHD1-like\tK22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-]"
					},
					{
						"name":"127868555 fidgetin-like protein 1 isoform X1\tK22766 FIGNL1; fidgetin-like protein 1 [EC:5.6.2.-]"
					},
					{
						"name":"127868556 fidgetin-like protein 1 isoform X1\tK22766 FIGNL1; fidgetin-like protein 1 [EC:5.6.2.-]"
					},
					{
						"name":"127845741 DNA repair-scaffolding protein-like\tK22806 SPIDR; DNA repair-scaffolding protein"
					},
					{
						"name":"127845742 DNA repair-scaffolding protein-like\tK22806 SPIDR; DNA repair-scaffolding protein"
					},
					{
						"name":"127839194 cilia- and flagella-associated protein 410-like\tK23456 CFAP410; cilla- and flagella-associated protein"
					},
					{
						"name":"127848160 hepatoma-derived growth factor-related protein 2-like\tK25065 HDGFL2; hepatoma-derived growth factor-related protein 2"
					},
					{
						"name":"127872702 zinc finger SWIM domain-containing protein 7-like isoform X1\tK25770 ZSWIM7; zinc finger SWIM domain-containing protein 7"
					},
					{
						"name":"127833567 BRCA2-interacting transcriptional repressor EMSY-like isoform X1\tK25790 EMSY; BRCA2-interacting transcriptional repressor EMSY"
					},
					{
						"name":"127876712 heat shock factor 2-binding protein-like isoform X1\tK25791 HSF2BP; heat shock factor 2-binding protein"
					},
					{
						"name":"127852897 protein MMS22-like isoform X1\tK26125 MMS22L; protein MMS22-like"
					},
					{
						"name":"127874166 PCNA-interacting partner-like isoform X1\tK27412 PARPBP; PCNA-interacting partner"
					},
					{
						"name":"127877547 uncharacterized protein LOC127877547 isoform X1\tK27803 HROB; homologous recombination OB-fold protein"
					},
					{
						"name":"127841481 DNA helicase MCM8-like isoform X1\tK10737 MCM8; DNA helicase MCM8 [EC:5.6.2.4]"
					},
					{
						"name":"127847782 uncharacterized protein LOC127847782\tK28623 MRNIP; MRN complex-interacting protein"
					},
					{
						"name":"127871010 RPA-related protein RADX-like\tK29002 RADX; RPA-related protein RADX"
					}
					]
				}
				]
			},
			{
				"name":"NHEJ (non-homologous end-joining)",
				"children":[
				{
					"name":"DNA-PK complex",
					"children":[
					{
						"name":"127843731 X-ray repair cross-complementing protein 6-like isoform X1\tK10884 XRCC6; ATP-dependent DNA helicase 2 subunit 1"
					},
					{
						"name":"127858403 X-ray repair cross-complementing protein 5-like isoform X1\tK10885 XRCC5; ATP-dependent DNA helicase 2 subunit 2"
					},
					{
						"name":"127866349 DNA-dependent protein kinase catalytic subunit-like isoform X1\tK06642 PRKDC; DNA-dependent protein kinase catalytic subunit [EC:2.7.11.1]"
					}
					]
				},
				{
					"name":"MRX complex",
					"children":[
					{
						"name":"127867645 double-strand break repair protein MRE11-like isoform X1\tK10865 MRE11; double-strand break repair protein MRE11"
					},
					{
						"name":"127877166 DNA repair protein RAD50-like\tK10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]"
					}
					]
				},
				{
					"name":"DNA Ligase 4 complex",
					"children":[
					{
						"name":"127862315 DNA ligase 4-like\tK10777 LIG4; DNA ligase 4 [EC:6.5.1.1]"
					},
					{
						"name":"127862389 DNA ligase 4-like\tK10777 LIG4; DNA ligase 4 [EC:6.5.1.1]"
					},
					{
						"name":"127835743 DNA repair protein XRCC4-like\tK10886 XRCC4; DNA-repair protein XRCC4"
					}
					]
				},
				{
					"name":"X-family DNA polymerases",
					"children":[
					{
						"name":"127839443 DNA polymerase lambda-like\tK03512 POLL; DNA polymerase lambda [EC:2.7.7.7 4.2.99.-]"
					},
					{
						"name":"127867389 DNA polymerase beta-like isoform X1\tK02330 POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-]"
					}
					]
				},
				{
					"name":"Other NHEJ factors",
					"children":[
					{
						"name":"127836357 aprataxin-like\tK10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]"
					},
					{
						"name":"127857090 tyrosyl-DNA phosphodiesterase 2-like isoform X1\tK19619 TDP2; tyrosyl-DNA phosphodiesterase 2 [EC:3.1.4.-]"
					},
					{
						"name":"127857616 structural maintenance of chromosomes flexible hinge domain-containing protein 1-like\tK23113 SMCHD1; structural maintenance of chromosomes flexible hinge domain-containing protein 1"
					},
					{
						"name":"127875261 uncharacterized protein LOC127875261\tK25772 PAXX; protein PAXX"
					},
					{
						"name":"127866687 jmjC domain-containing protein 8-like isoform X1\tK25792 JMJD8; jumonji domain-containing protein 8"
					}
					]
				}
				]
			},
			{
				"name":"FA (Fanconi anemia) pathway",
				"children":[
				{
					"name":"FA core complex",
					"children":[
					{
						"name":"127873784 E3 ubiquitin-protein ligase FANCL-like isoform X1\tK10606 FANCL; E3 ubiquitin-protein ligase FANCL [EC:2.3.2.27]"
					},
					{
						"name":"127872885 Fanconi anemia group M protein-like\tK10896 FANCM; fanconi anemia group M protein"
					},
					{
						"name":"127866555 Fanconi anemia core complex-associated protein 24-like\tK10898 FAAP24; fanconi anemia-associated protein"
					}
					]
				},
				{
					"name":"FA core complex binding factors",
					"children":[
					{
						"name":"127842345 transcription factor HES-4-like\tK06054 HES1; hairy and enhancer of split 1"
					},
					{
						"name":"127881451 protein hairy-like\tK06054 HES1; hairy and enhancer of split 1"
					},
					{
						"name":"127881523 centromere protein S-like\tK11511 APITD1; centromere protein S"
					},
					{
						"name":"127866515 centromere protein X-like\tK15360 STRA13; centromere protein X"
					},
					{
						"name":"127840668 ubiquitin-conjugating enzyme E2 T-like\tK13960 UBE2T; ubiquitin-conjugating enzyme E2 T [EC:2.3.2.23]"
					}
					]
				},
				{
					"name":"Bloom's syndrome complex (BTR)",
					"children":[
					{
						"name":"127847317 DNA topoisomerase 3-beta-1-like\tK03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]"
					},
					{
						"name":"127867203 DNA topoisomerase 3-alpha-like isoform X1\tK03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]"
					},
					{
						"name":"127869762 DNA topoisomerase 3-alpha-like\tK03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]"
					},
					{
						"name":"127861652 uncharacterized protein LOC127861652\tK15365 RMI2; RecQ-mediated genome instability protein 2"
					},
					{
						"name":"127861653 uncharacterized protein LOC127861653 isoform X1\tK15365 RMI2; RecQ-mediated genome instability protein 2"
					},
					{
						"name":"127861655 uncharacterized protein LOC127861655\tK15365 RMI2; RecQ-mediated genome instability protein 2"
					}
					]
				},
				{
					"name":"FANCD2-I complex",
					"children":[
					{
						"name":"127880818 Fanconi anemia group D2 protein-like isoform X1\tK10891 FANCD2; fanconi anemia group D2 protein"
					},
					{
						"name":"127880820 Fanconi anemia group D2 protein-like\tK10891 FANCD2; fanconi anemia group D2 protein"
					},
					{
						"name":"127857140 Fanconi anemia group I protein-like isoform X1\tK10895 FANCI; fanconi anemia group I protein"
					}
					]
				},
				{
					"name":"Downstream FA components",
					"children":[
					{
						"name":"127876253 breast cancer type 2 susceptibility protein homolog isoform X1\tK08775 BRCA2; breast cancer 2 susceptibility protein"
					}
					]
				},
				{
					"name":"Other FA pathway factors",
					"children":[
					{
						"name":"127852356 fanconi-associated nuclease 1-like isoform X1\tK15363 FAN1; fanconi-associated nuclease 1 [EC:3.1.21.- 3.1.4.1]"
					},
					{
						"name":"127857615 DNA repair protein RAD51 homolog 1\tK04482 RAD51; DNA repair protein RAD51"
					},
					{
						"name":"127871932 DNA repair protein RAD51 homolog 3-like\tK10870 RAD51L2; RAD51-like protein 2"
					},
					{
						"name":"127867421 telomere length regulation protein TEL2 homolog isoform X1\tK11137 TELO2; telomere length regulation protein"
					},
					{
						"name":"127857631 WD repeat-containing protein 48-like isoform X1\tK15361 WDR48; WD repeat-containing protein 48"
					}
					]
				}
				]
			},
			{
				"name":"Other DSBR factors",
				"children":[
				{
					"name":"Protein phosphatase 6",
					"children":[
					{
						"name":"127837541 serine\/threonine-protein phosphatase 6 catalytic subunit\tK15498 PPP6C; serine\/threonine-protein phosphatase 6 catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"127848531 serine\/threonine-protein phosphatase 6 regulatory subunit 3-like isoform X1\tK15501 PPP6R3; serine\/threonine-protein phosphatase 6 regulatory subunit 3"
					},
					{
						"name":"127855674 serine\/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A-like\tK15502 ANKRD28; serine\/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A"
					},
					{
						"name":"127855998 serine\/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A-like\tK15502 ANKRD28; serine\/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A"
					}
					]
				},
				{
					"name":"Ubiquitin ligases",
					"children":[
					{
						"name":"127873347 E3 ubiquitin-protein ligase RNF8-like\tK10667 RNF8; E3 ubiquitin-protein ligase RNF8 [EC:2.3.2.27]"
					},
					{
						"name":"127873348 E3 ubiquitin-protein ligase RNF8-like\tK10667 RNF8; E3 ubiquitin-protein ligase RNF8 [EC:2.3.2.27]"
					},
					{
						"name":"127876751 E3 ubiquitin-protein ligase HERC2-like isoform X1\tK10595 HERC2; E3 ubiquitin-protein ligase HERC2 [EC:2.3.2.26]"
					},
					{
						"name":"127876902 E3 ubiquitin-protein ligase HERC2-like\tK10595 HERC2; E3 ubiquitin-protein ligase HERC2 [EC:2.3.2.26]"
					}
					]
				},
				{
					"name":"Others",
					"children":[
					{
						"name":"127861442 telomerase Cajal body protein 1-like isoform X1\tK23314 WRAP53; telomerase Cajal body protein 1"
					},
					{
						"name":"127832643 zinc finger CW-type PWWP domain protein 1-like isoform X1\tK24688 ZCWPW1; zinc finger CW-type PWWP domain protein 1"
					},
					{
						"name":"127862193 WD repeat-containing protein 70-like\tK24752 WDR70; WD repeat-containing protein 70"
					},
					{
						"name":"127862440 WD repeat-containing protein 70-like\tK24752 WDR70; WD repeat-containing protein 70"
					},
					{
						"name":"127868343 WD repeat-containing protein 76-like isoform X1\tK24755 WDR76; WD repeat-containing protein 76"
					},
					{
						"name":"127842548 abasic site processing protein HMCES-like isoform X1\tK28434 HMCES; abasic site processing protein HMCES"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"TLS (translesion DNA synthesis) factors",
			"children":[
			{
				"name":"Y-family DNA polymerases",
				"children":[
				{
					"name":"127874832 DNA polymerase eta-like isoform X1\tK03509 POLH; DNA polymerase eta [EC:2.7.7.7]"
				},
				{
					"name":"127879748 DNA polymerase iota-like\tK03510 POLI; DNA polymerase iota [EC:2.7.7.7]"
				},
				{
					"name":"127877946 DNA polymerase kappa-like isoform X1\tK03511 POLK; DNA polymerase kappa [EC:2.7.7.7]"
				}
				]
			},
			{
				"name":"B-family DNA polymerases"
			},
			{
				"name":"A-family DNA polymerase"
			},
			{
				"name":"Rad6 epistasis group",
				"children":[
				{
					"name":"127877836 ubiquitin-conjugating enzyme E2-17 kDa isoform X1\tK10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]"
				},
				{
					"name":"127845170 ubiquitin-conjugating enzyme E2 variant 1-like\tK10704 UBE2V; ubiquitin-conjugating enzyme E2 variant"
				},
				{
					"name":"127881792 ubiquitin-conjugating enzyme E2 N isoform X1\tK10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]"
				}
				]
			},
			{
				"name":"Other TLS factors",
				"children":[
				{
					"name":"127866723 proliferating cell nuclear antigen-like\tK04802 PCNA; proliferating cell nuclear antigen"
				},
				{
					"name":"127882041 PCNA-associated factor-like\tK28763 PCLAF; PCNA-associated factor"
				},
				{
					"name":"127874166 PCNA-interacting partner-like isoform X1\tK27412 PARPBP; PCNA-interacting partner"
				},
				{
					"name":"127873266 DNA-dependent metalloprotease SPRTN-like\tK24051 SPRTN; SprT-like domain-contaning protein Spartan"
				},
				{
					"name":"127876050 uncharacterized protein LOC127876050\tK26957 GCNA; germ cell nuclear acidic protein"
				},
				{
					"name":"127877077 uncharacterized protein LOC127877077\tK26957 GCNA; germ cell nuclear acidic protein"
				}
				]
			}
			]
		},
		{
			"name":"Check point factors",
			"children":[
			{
				"name":"Rad9-Hus1-Rad1 complex",
				"children":[
				{
					"name":"127865194 cell cycle checkpoint control protein RAD9A-like isoform X1\tK10994 RAD9A; cell cycle checkpoint control protein RAD9A [EC:3.1.11.2]"
				},
				{
					"name":"127859822 checkpoint protein HUS1-like isoform X1\tK10903 HUS1; HUS1 checkpoint protein"
				},
				{
					"name":"127853478 cell cycle checkpoint protein RAD1-like\tK02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]"
				}
				]
			},
			{
				"name":"HRAD17(Rad24)-RFC complex",
				"children":[
				{
					"name":"127862002 cell cycle checkpoint protein RAD17-like\tK06662 HRAD17; cell cycle checkpoint protein"
				},
				{
					"name":"127834234 replication factor C subunit 4-like\tK10755 RFC2_4; replication factor C subunit 2\/4"
				},
				{
					"name":"127834385 replication factor C subunit 4-like\tK10755 RFC2_4; replication factor C subunit 2\/4"
				},
				{
					"name":"127871442 replication factor C subunit 2-like isoform X1\tK10755 RFC2_4; replication factor C subunit 2\/4"
				},
				{
					"name":"127834383 replication factor C subunit 5-like\tK10756 RFC3_5; replication factor C subunit 3\/5"
				},
				{
					"name":"127877752 replication factor C subunit 3-like\tK10756 RFC3_5; replication factor C subunit 3\/5"
				}
				]
			},
			{
				"name":"Rad17-Mec3-Ddc1 complex",
				"children":[
				{
					"name":"127853478 cell cycle checkpoint protein RAD1-like\tK02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]"
				}
				]
			},
			{
				"name":"FPC (fork protection complex)",
				"children":[
				{
					"name":"127861177 protein timeless homolog isoform X1\tK10997 TIMELESS; replication fork protection complex subunit TIMELESS\/Tof1\/Swi1"
				}
				]
			},
			{
				"name":"Triple T complex",
				"children":[
				{
					"name":"127867421 telomere length regulation protein TEL2 homolog isoform X1\tK11137 TELO2; telomere length regulation protein"
				},
				{
					"name":"127881932 TELO2-interacting protein 1 homolog\tK20403 TTI1; TELO2-interacting protein 1"
				}
				]
			},
			{
				"name":"BAG6-UBL4A-GET4 complex",
				"children":[
				{
					"name":"127837639 large proline-rich protein BAG6-like isoform X1\tK23390 BAG6; large proline-rich protein BAG6"
				},
				{
					"name":"127865045 ubiquitin-like protein 4A\tK23388 UBL4; ubiquitin-like protein 4"
				},
				{
					"name":"127868730 Golgi to ER traffic protein 4 homolog\tK23387 GET4; golgi to ER traffic protein 4"
				}
				]
			},
			{
				"name":"SOSS complex",
				"children":[
				{
					"name":"127875908 integrator complex subunit 3-like isoform X1\tK13140 INTS3; integrator complex subunit 3 (SOSS complex subunit A)"
				},
				{
					"name":"127845503 SOSS complex subunit B1-like isoform X1\tK28889 NABP; SOSS complex subunit B"
				},
				{
					"name":"127834530 SOSS complex subunit C-like\tK28890 INIP; SOSS complex subunit C"
				}
				]
			},
			{
				"name":"Other check point factors",
				"children":[
				{
					"name":"127832548 serine\/threonine-protein kinase ATR-like isoform X1\tK06640 ATR; serine\/threonine-protein kinase ATR [EC:2.7.11.1]"
				},
				{
					"name":"127852742 serine-protein kinase ATM-like isoform X1\tK04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]"
				},
				{
					"name":"127868280 serine\/threonine-protein kinase Chk1-like\tK02216 CHEK1; serine\/threonine-protein kinase CHEK1 [EC:2.7.11.1]"
				},
				{
					"name":"127868312 serine\/threonine-protein kinase Chk1-like\tK02216 CHEK1; serine\/threonine-protein kinase CHEK1 [EC:2.7.11.1]"
				},
				{
					"name":"127852373 serine\/threonine-protein kinase Chk2-like isoform X1\tK06641 CHEK2; serine\/threonine-protein kinase CHEK2 [EC:2.7.11.1]"
				},
				{
					"name":"127842558 M-phase inducer phosphatase 1-like\tK05866 CDC25B; M-phase inducer phosphatase 2 [EC:3.1.3.48]"
				},
				{
					"name":"127856871 M-phase inducer phosphatase 1-like isoform X1\tK05866 CDC25B; M-phase inducer phosphatase 2 [EC:3.1.3.48]"
				},
				{
					"name":"127861707 M-phase inducer phosphatase-like\tK05866 CDC25B; M-phase inducer phosphatase 2 [EC:3.1.3.48]"
				},
				{
					"name":"127847425 14-3-3 protein homolog 2-like\tK16197 YWHAB_Q_Z; 14-3-3 protein beta\/theta\/zeta"
				},
				{
					"name":"127847426 14-3-3 protein homolog 2-like\tK16197 YWHAB_Q_Z; 14-3-3 protein beta\/theta\/zeta"
				},
				{
					"name":"127848440 14-3-3-like protein 2\tK16197 YWHAB_Q_Z; 14-3-3 protein beta\/theta\/zeta"
				},
				{
					"name":"127855693 14-3-3 protein beta\/alpha-like\tK16197 YWHAB_Q_Z; 14-3-3 protein beta\/theta\/zeta"
				},
				{
					"name":"127856124 14-3-3 protein beta\/alpha-like\tK16197 YWHAB_Q_Z; 14-3-3 protein beta\/theta\/zeta"
				},
				{
					"name":"127862463 14-3-3-like protein 2\tK16197 YWHAB_Q_Z; 14-3-3 protein beta\/theta\/zeta"
				},
				{
					"name":"127882249 14-3-3-like protein 1\tK16197 YWHAB_Q_Z; 14-3-3 protein beta\/theta\/zeta"
				},
				{
					"name":"127854654 LOW QUALITY PROTEIN: 14-3-3 protein epsilon-like\tK06630 YWHAE; 14-3-3 protein epsilon"
				},
				{
					"name":"127854666 14-3-3 protein epsilon-like\tK06630 YWHAE; 14-3-3 protein epsilon"
				},
				{
					"name":"127856081 14-3-3 protein zeta\/delta-like\tK06630 YWHAE; 14-3-3 protein epsilon"
				},
				{
					"name":"127856387 14-3-3 protein zeta\/delta-like\tK06630 YWHAE; 14-3-3 protein epsilon"
				},
				{
					"name":"127852999 wee1-like protein kinase 1-A isoform X1\tK06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]"
				},
				{
					"name":"127863129 mediator of DNA damage checkpoint protein 1-like isoform X1\tK20780 MDC1; mediator of DNA damage checkpoint protein 1"
				},
				{
					"name":"127881966 plastin-2-like isoform X1\tK17336 PLS3; plastin-3"
				},
				{
					"name":"127841633 serine\/threonine-protein kinase Nek1-like isoform X1\tK08857 NEK1_4_5; serine\/threonine-protein kinase Nek1\/4\/5 [EC:2.7.11.1]"
				},
				{
					"name":"127877140 serine\/threonine-protein kinase Nek4-like isoform X1\tK08857 NEK1_4_5; serine\/threonine-protein kinase Nek1\/4\/5 [EC:2.7.11.1]"
				},
				{
					"name":"127862983 serine\/threonine-protein kinase Nek10-like\tK20879 NEK10; serine\/threonine-protein kinase Nek10 [EC:2.7.11.1]"
				},
				{
					"name":"127863335 serine\/threonine-protein kinase Nek10-like isoform X1\tK20879 NEK10; serine\/threonine-protein kinase Nek10 [EC:2.7.11.1]"
				},
				{
					"name":"127844051 serine\/threonine-protein kinase Nek11-like isoform X1\tK20880 NEK11; serine\/threonine-protein kinase Nek11 [EC:2.7.11.1]"
				},
				{
					"name":"127850706 protein downstream neighbor of Son-like\tK22422 DONSON; protein downstream neighbor of Son"
				},
				{
					"name":"127834458 vacuolar protein sorting-associated protein 4B-like\tK12196 VPS4; vacuolar protein-sorting-associated protein 4"
				},
				{
					"name":"127835191 vacuolar protein sorting-associated protein 4B-like isoform X1\tK12196 VPS4; vacuolar protein-sorting-associated protein 4"
				},
				{
					"name":"127845675 vacuolar protein sorting-associated protein 4B-like isoform X1\tK12196 VPS4; vacuolar protein-sorting-associated protein 4"
				},
				{
					"name":"127845681 vacuolar protein sorting-associated protein 4A-like isoform X1\tK12196 VPS4; vacuolar protein-sorting-associated protein 4"
				},
				{
					"name":"127871668 abscission\/NoCut checkpoint regulator-like isoform X1\tK24778 ZFYVE19; abscission\/NoCut checkpoint regulator"
				},
				{
					"name":"127871714 replication stress response regulator SDE2-like\tK25059 SDE2; replication stress response regulator SDE2"
				}
				]
			}
			]
		},
		{
			"name":"Other factors with a suspected DNA repair function",
			"children":[
			{
				"name":"DNA polymerases",
				"children":[
				{
					"name":"127868758 DNA-directed primase\/polymerase protein-like isoform X1\tK22761 PRIMPOL; DNA-directed primase\/polymerase protein [EC:2.7.7.102 2.7.7.7]"
				}
				]
			},
			{
				"name":"Nucleases",
				"children":[
				{
					"name":"127831141 5' exonuclease Apollo-like\tK15341 DCLRE1B; DNA cross-link repair 1B protein [EC:3.1.-.-]"
				},
				{
					"name":"127843884 exonuclease V-like isoform X1\tK17815 EXO5; exonuclease V [EC:3.1.-.-]"
				},
				{
					"name":"127857020 endonuclease V-like isoform X1\tK21813 ENDOV; endonuclease V [EC:3.1.26.-]"
				},
				{
					"name":"127877613 uncharacterized protein LOC127877613\tK21411 ANKLE1; ankyrin repeat and LEM domain-containing protein 1"
				}
				]
			},
			{
				"name":"Helicases",
				"children":[
				{
					"name":"127871070 helicase POLQ-like\tK19178 HELQ; POLQ-like helicase [EC:5.6.2.4]"
				}
				]
			},
			{
				"name":"PSO4 complex",
				"children":[
				{
					"name":"127844548 pre-mRNA-processing factor 19-like\tK10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]"
				},
				{
					"name":"127852159 cell division cycle 5-like protein\tK12860 CDC5L; pre-mRNA-splicing factor CDC5\/CEF1"
				},
				{
					"name":"127832661 pre-mRNA-splicing factor SPF27-like\tK12861 BCAS2; pre-mRNA-splicing factor SPF27"
				},
				{
					"name":"127869180 pre-mRNA-splicing factor SPF27-like isoform X1\tK12861 BCAS2; pre-mRNA-splicing factor SPF27"
				},
				{
					"name":"127878897 pleiotropic regulator 1-like\tK12862 PLRG1; pleiotropic regulator 1"
				}
				]
			},
			{
				"name":"Modulation of nucleotide pools",
				"children":[
				{
					"name":"127876871 nucleotide triphosphate diphosphatase NUDT15-like\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]"
				},
				{
					"name":"127852132 8-oxo-dGDP phosphatase NUDT18-like isoform X1\tK17817 NUDT18; 8-oxo-dGDP phosphatase [EC:3.6.1.58]"
				},
				{
					"name":"127859015 deoxyuridine 5'-triphosphate nucleotidohydrolase-like\tK01520 dut; dUTP diphosphatase [EC:3.6.1.23]"
				},
				{
					"name":"127859016 deoxyuridine 5'-triphosphate nucleotidohydrolase-like\tK01520 dut; dUTP diphosphatase [EC:3.6.1.23]"
				},
				{
					"name":"127867004 deoxyuridine 5'-triphosphate nucleotidohydrolase-like isoform X1\tK01520 dut; dUTP diphosphatase [EC:3.6.1.23]"
				},
				{
					"name":"127879234 ribonucleoside-diphosphate reductase large subunit-like isoform X1\tK10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]"
				},
				{
					"name":"127861616 ribonucleoside-diphosphate reductase small chain-like\tK10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic type",
		"children":[
		{
			"name":"SSBR (single strand breaks repair)",
			"children":[
			{
				"name":"Direct repair",
				"children":[
				{
					"name":"127865737 methylated-DNA--protein-cysteine methyltransferase-like isoform X1\tK00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]"
				},
				{
					"name":"127834725 deoxyribodipyrimidine photo-lyase-like isoform X1\tK01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]"
				}
				]
			},
			{
				"name":"BER (base exicision repair)",
				"children":[
				{
					"name":"DNA glycosylases",
					"children":[
					{
						"name":"127841570 uracil-DNA glycosylase-like isoform X1\tK03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]"
					},
					{
						"name":"127855837 uracil-DNA glycosylase-like\tK03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]"
					},
					{
						"name":"127855838 uracil-DNA glycosylase-like\tK03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]"
					},
					{
						"name":"127865786 uncharacterized protein LOC127865786 isoform X1\tK03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]"
					}
					]
				},
				{
					"name":"AP endonucleases"
				},
				{
					"name":"RecJ"
				},
				{
					"name":"DNA ligase"
				},
				{
					"name":"DNA polymerase I"
				}
				]
			},
			{
				"name":"NER (nucleotide excision repair)",
				"children":[
				{
					"name":"GGR (global genome repair) factors"
				},
				{
					"name":"TCR (transcription coupled repair) factors",
					"children":[
					{
						"name":"DNA-directed RNA polymerase complex (RNAP)"
					},
					{
						"name":"TRCF (transcription-repair coupling factor)"
					}
					]
				}
				]
			},
			{
				"name":"MMR (mismatch excision repair)",
				"children":[
				{
					"name":"Mismatch and loop recognition factors"
				},
				{
					"name":"Molecular matchmaker"
				},
				{
					"name":"Strand discrimination factor"
				},
				{
					"name":"DNA exonucleases"
				},
				{
					"name":"DNA polymerase III holoenzyme"
				},
				{
					"name":"DNA ligase"
				},
				{
					"name":"Other MMR factors"
				}
				]
			}
			]
		},
		{
			"name":"DSBR (double strand breaks repair)",
			"children":[
			{
				"name":"HR (homologous recombination)",
				"children":[
				{
					"name":"RecBC pathway proteins"
				},
				{
					"name":"RecFOR pathway proteins"
				},
				{
					"name":"AddAB pathway proteins"
				},
				{
					"name":"Other HR factor"
				},
				{
					"name":"Archaeal homologous recombinant proteins"
				}
				]
			},
			{
				"name":"NHEJ (non-homologous end-joining)",
				"children":[
				{
					"name":"Two-component NHEJ DNA repair complex"
				},
				{
					"name":"SHIIR (short-homology-independent illegitimate recombination)",
					"children":[
					{
						"name":"Facilitator"
					},
					{
						"name":"Supressor"
					}
					]
				},
				{
					"name":"SHDIR (short-homology-dependent illegitimate recombination)",
					"children":[
					{
						"name":"RecET pathway"
					},
					{
						"name":"Facilitator"
					},
					{
						"name":"Supressor",
						"children":[
						{
							"name":"127831647 putative ATP-dependent DNA helicase Q1\tK03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]"
						},
						{
							"name":"127838516 ATP-dependent DNA helicase RecQ-like\tK03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]"
						},
						{
							"name":"127842655 ATP-dependent DNA helicase RecQ-like\tK03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]"
						},
						{
							"name":"127843076 uncharacterized protein LOC127843076\tK03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]"
						},
						{
							"name":"127848364 ATP-dependent DNA helicase RecQ-like\tK03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]"
						},
						{
							"name":"127854223 uncharacterized protein LOC127854223\tK03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]"
						},
						{
							"name":"127862342 ATP-dependent DNA helicase RecQ-like\tK03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]"
						},
						{
							"name":"127864184 uncharacterized protein LOC127864184\tK03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]"
						},
						{
							"name":"127865207 uncharacterized protein LOC127865207\tK03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]"
						},
						{
							"name":"127874207 ATP-dependent DNA helicase RecQ-like\tK03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]"
						},
						{
							"name":"127874814 putative ATP-dependent DNA helicase Q1\tK03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]"
						},
						{
							"name":"127877727 uncharacterized protein LOC127877727\tK03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]"
						},
						{
							"name":"127879570 putative ATP-dependent DNA helicase Q1\tK03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]"
						}
						]
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"TLS (translesion DNA synthesis) factors",
			"children":[
			{
				"name":"Y-family DNA polymerases"
			},
			{
				"name":"Other SOS response factors"
			}
			]
		},
		{
			"name":"Other factors with a suspected DNA repair function",
			"children":[
			{
				"name":"DNA polymerase"
			},
			{
				"name":"DNA helicases"
			},
			{
				"name":"Modulation of nucleotide pools",
				"children":[
				{
					"name":"127876871 nucleotide triphosphate diphosphatase NUDT15-like\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]"
				},
				{
					"name":"127859015 deoxyuridine 5'-triphosphate nucleotidohydrolase-like\tK01520 dut; dUTP diphosphatase [EC:3.6.1.23]"
				},
				{
					"name":"127859016 deoxyuridine 5'-triphosphate nucleotidohydrolase-like\tK01520 dut; dUTP diphosphatase [EC:3.6.1.23]"
				},
				{
					"name":"127867004 deoxyuridine 5'-triphosphate nucleotidohydrolase-like isoform X1\tK01520 dut; dUTP diphosphatase [EC:3.6.1.23]"
				}
				]
			},
			{
				"name":"Others"
			}
			]
		}
		]
	}
	]
}