{
	"name":"ebs03016",
	"children":[
	{
		"name":"Eukaryotic type",
		"children":[
		{
			"name":"5'processing factors",
			"children":[
			{
				"name":"Ribonucrease P"
			}
			]
		},
		{
			"name":"3'processing and CCA adding factors",
			"children":[
			{
				"name":"3'processing factors"
			},
			{
				"name":"CCA adding factors",
				"children":[
				{
					"name":"ECTOBSL9_0360 cca; 2', 3'-cyclic nucleotide 2'-phosphodiesterase\tK00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]"
				}
				]
			}
			]
		},
		{
			"name":"tRNA spricing factors",
			"children":[
			{
				"name":"tRNA splicing endonuclease complex"
			},
			{
				"name":"tRNA splicing ligase complex"
			},
			{
				"name":"Other tRNA splicing factors"
			}
			]
		},
		{
			"name":"tRNA transport factors",
			"children":[
			{
				"name":"tRNA export factors"
			},
			{
				"name":"tRNA import factors"
			}
			]
		},
		{
			"name":"Aminoacyl-tRNA synthetases (AARSs)",
			"children":[
			{
				"name":"Multi-aminoacyl-tRNA synthetase complex (MSC)",
				"children":[
				{
					"name":"ECTOBSL9_0030 glutamyl-tRNA synthetase\tK01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]"
				},
				{
					"name":"ECTOBSL9_1821 proline--tRNA ligase\tK01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]"
				},
				{
					"name":"ECTOBSL9_0751 ileS; isoleucine--tRNA ligase\tK01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]"
				},
				{
					"name":"ECTOBSL9_1787 leuS; leucine--tRNA ligase\tK01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]"
				},
				{
					"name":"ECTOBSL9_0604 metG; methionine--tRNA ligase\tK01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]"
				},
				{
					"name":"ECTOBSL9_2940 glutamate--tRNA ligase\tK01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18]"
				},
				{
					"name":"ECTOBSL9_1395 argS; arginine--tRNA ligase\tK01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]"
				},
				{
					"name":"ECTOBSL9_3216 lysyl-tRNA synthetase\tK04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]"
				},
				{
					"name":"ECTOBSL9_1830 aspartyl-tRNA synthetase\tK01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]"
				}
				]
			},
			{
				"name":"Other AARSs",
				"children":[
				{
					"name":"ECTOBSL9_2497 alanyl-tRNA synthetase\tK01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]"
				},
				{
					"name":"ECTOBSL9_2596 threonyl-tRNA synthetase\tK01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]"
				},
				{
					"name":"ECTOBSL9_2091 seryl-tRNA synthetase\tK01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]"
				},
				{
					"name":"ECTOBSL9_1946 cysteinyl-tRNA synthetase\tK01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]"
				},
				{
					"name":"ECTOBSL9_2039 valyl-tRNA synthetase\tK01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]"
				},
				{
					"name":"ECTOBSL9_3183 histidinol dehydrogenase\tK01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]"
				},
				{
					"name":"ECTOBSL9_2600 phenylalanyl-tRNA synthetase subunit alpha\tK01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]"
				},
				{
					"name":"ECTOBSL9_2601 phenylalanyl-tRNA synthetase\tK01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]"
				},
				{
					"name":"ECTOBSL9_1768 tyrosine--tRNA ligase\tK01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]"
				},
				{
					"name":"ECTOBSL9_3070 tryptophan--tRNA ligase\tK01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]"
				}
				]
			},
			{
				"name":"Trans-editing factors",
				"children":[
				{
					"name":"ECTOBSL9_0828 D-tyrosyl-tRNA(Tyr) deacylase\tK07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]"
				}
				]
			},
			{
				"name":"AARS associated factors",
				"children":[
				{
					"name":"ECTOBSL9_2400 zinc-binding protein\tK02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]"
				}
				]
			}
			]
		},
		{
			"name":"tRNA modification factors",
			"children":[
			{
				"name":"Deaminases"
			},
			{
				"name":"Dihydorouridine synthases"
			},
			{
				"name":"Methylthiotransferase",
				"children":[
				{
					"name":"ECTOBSL9_1781 hypothetical protein\tK06168 CDK5RAP1; tRNA-2-methylthio-N6-dimethylallyladenosine synthase [EC:2.8.4.3]"
				}
				]
			},
			{
				"name":"Methyltransferases",
				"children":[
				{
					"name":"ECTOBSL9_0858 tRNA (guanine-N7)-methyltransferase\tK03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33]"
				}
				]
			},
			{
				"name":"Psudouridine synthases",
				"children":[
				{
					"name":"ECTOBSL9_2072 truA; tRNA pseudouridine synthase A\tK06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]"
				},
				{
					"name":"ECTOBSL9_0134 pseudouridine synthase\tK03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]"
				},
				{
					"name":"ECTOBSL9_2623 pseudouridine synthase\tK06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]"
				}
				]
			},
			{
				"name":"Thiolation factors",
				"children":[
				{
					"name":"ECTOBSL9_3087 cysteine desulfurase\tK04487 iscS; cysteine desulfurase [EC:2.8.1.7]"
				},
				{
					"name":"ECTOBSL9_3167 cysteine desulfurase\tK04487 iscS; cysteine desulfurase [EC:2.8.1.7]"
				},
				{
					"name":"ECTOBSL9_3194 cysteine desulfurase\tK04487 iscS; cysteine desulfurase [EC:2.8.1.7]"
				}
				]
			},
			{
				"name":"KEOPS\/EKC complex"
			},
			{
				"name":"Elongator complex"
			},
			{
				"name":"Elongator related proteins"
			},
			{
				"name":"Other tRNA modification factors",
				"children":[
				{
					"name":"ECTOBSL9_0889 tRNA threonylcarbamoyladenosine biosynthesis protein RimN\tK07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]"
				},
				{
					"name":"ECTOBSL9_1917 tRNA dimethylallyltransferase\tK00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]"
				},
				{
					"name":"ECTOBSL9_1049 tRNA modification GTPase MnmE\tK03650 mnmE; tRNA modification GTPase [EC:3.6.-.-]"
				},
				{
					"name":"ECTOBSL9_1160 gidA; tRNA uridine 5-carboxymethylaminomethyl modification protein\tK03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme"
				}
				]
			}
			]
		},
		{
			"name":"tRNA degradation factors",
			"children":[
			{
				"name":"TRAMP complex"
			},
			{
				"name":"Rapid tRNA decay (RTD) pathway factors",
				"children":[
				{
					"name":"ECTOBSL9_1200 3'-5'-bisphosphate nucleotidase\tK01082 cysQ; 3'(2'), 5'-bisphosphate nucleotidase [EC:3.1.3.7]"
				},
				{
					"name":"ECTOBSL9_2217 adenosine-3'(2'),5'-bisphosphate nucleotidase\tK01082 cysQ; 3'(2'), 5'-bisphosphate nucleotidase [EC:3.1.3.7]"
				}
				]
			},
			{
				"name":"Other tRNA degradation factors"
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic type",
		"children":[
		{
			"name":"5'processing factors",
			"children":[
			{
				"name":"Ribonucrease P",
				"children":[
				{
					"name":"ECTOBSL9_1047 hypothetical protein\tK03536 rnpA; ribonuclease P protein component [EC:3.1.26.5]"
				},
				{
					"name":"ECTOBSL9_0418 bacterial RNase P\tK01978 rnpB; RNase P catalytic RNA component"
				}
				]
			}
			]
		},
		{
			"name":"3'processing and CCA adding factors",
			"children":[
			{
				"name":"3'processing factors",
				"children":[
				{
					"name":"ECTOBSL9_2151 ribonuclease T\tK03683 rnt; ribonuclease T [EC:3.1.13.-]"
				},
				{
					"name":"ECTOBSL9_0593 rph; ribonuclease PH\tK00989 rph; ribonuclease PH [EC:2.7.7.56]"
				},
				{
					"name":"ECTOBSL9_1270 ribonuclease D\tK03684 rnd; ribonuclease D [EC:3.1.13.5]"
				}
				]
			},
			{
				"name":"CCA adding factors",
				"children":[
				{
					"name":"ECTOBSL9_0360 cca; 2', 3'-cyclic nucleotide 2'-phosphodiesterase\tK00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]"
				}
				]
			}
			]
		},
		{
			"name":"tRNA spricing factors",
			"children":[
			{
				"name":"tRNA splicing endonucleases"
			},
			{
				"name":"tRNA splicing ligases"
			},
			{
				"name":"Other tRNA splicing factors",
				"children":[
				{
					"name":"ECTOBSL9_2017 hypothetical protein\tK01975 thpR; RNA 2',3'-cyclic 3'-phosphodiesterase [EC:3.1.4.58]"
				}
				]
			}
			]
		},
		{
			"name":"tRNA transport factors",
			"children":[
			{
				"name":"tRNA export factors",
				"children":[
				{
					"name":"ECTOBSL9_2651 ABC transporter ATP-binding protein\tK06020 ettA; energy-dependent translational throttle protein EttA"
				}
				]
			}
			]
		},
		{
			"name":"Aminoacyl-tRNA synthetases (AARSs)",
			"children":[
			{
				"name":"Multi-aminoacyl-tRNA synthetase complex (MSC)",
				"children":[
				{
					"name":"ECTOBSL9_1787 leuS; leucine--tRNA ligase\tK01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]"
				},
				{
					"name":"ECTOBSL9_1821 proline--tRNA ligase\tK01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]"
				}
				]
			},
			{
				"name":"Other AARSs",
				"children":[
				{
					"name":"ECTOBSL9_1768 tyrosine--tRNA ligase\tK01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]"
				},
				{
					"name":"ECTOBSL9_3070 tryptophan--tRNA ligase\tK01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]"
				},
				{
					"name":"ECTOBSL9_2596 threonyl-tRNA synthetase\tK01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]"
				},
				{
					"name":"ECTOBSL9_0751 ileS; isoleucine--tRNA ligase\tK01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]"
				},
				{
					"name":"ECTOBSL9_3216 lysyl-tRNA synthetase\tK04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]"
				},
				{
					"name":"ECTOBSL9_2497 alanyl-tRNA synthetase\tK01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]"
				},
				{
					"name":"ECTOBSL9_2039 valyl-tRNA synthetase\tK01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]"
				},
				{
					"name":"ECTOBSL9_0604 metG; methionine--tRNA ligase\tK01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]"
				},
				{
					"name":"ECTOBSL9_2091 seryl-tRNA synthetase\tK01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]"
				},
				{
					"name":"ECTOBSL9_1830 aspartyl-tRNA synthetase\tK01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]"
				},
				{
					"name":"ECTOBSL9_0848 glycyl-tRNA synthetase\tK01878 glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14]"
				},
				{
					"name":"ECTOBSL9_0847 glyS; glycyl-tRNA ligase\tK01879 glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14]"
				},
				{
					"name":"ECTOBSL9_1946 cysteinyl-tRNA synthetase\tK01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]"
				},
				{
					"name":"ECTOBSL9_0030 glutamyl-tRNA synthetase\tK01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]"
				},
				{
					"name":"ECTOBSL9_2940 glutamate--tRNA ligase\tK01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18]"
				},
				{
					"name":"ECTOBSL9_1395 argS; arginine--tRNA ligase\tK01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]"
				},
				{
					"name":"ECTOBSL9_2600 phenylalanyl-tRNA synthetase subunit alpha\tK01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]"
				},
				{
					"name":"ECTOBSL9_2601 phenylalanyl-tRNA synthetase\tK01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]"
				},
				{
					"name":"ECTOBSL9_3183 histidinol dehydrogenase\tK01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]"
				}
				]
			},
			{
				"name":"Trans-editing factors",
				"children":[
				{
					"name":"ECTOBSL9_0828 D-tyrosyl-tRNA(Tyr) deacylase\tK07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]"
				}
				]
			}
			]
		},
		{
			"name":"tRNA modification factors",
			"children":[
			{
				"name":"Deaminases",
				"children":[
				{
					"name":"ECTOBSL9_0075 hypothetical protein\tK11991 tadA; tRNA(adenine34) deaminase [EC:3.5.4.33]"
				}
				]
			},
			{
				"name":"Dihydorouridine synthases",
				"children":[
				{
					"name":"ECTOBSL9_1461 tRNA-dihydrouridine synthase B\tK05540 dusB; tRNA-dihydrouridine synthase B [EC:1.-.-.-]"
				}
				]
			},
			{
				"name":"Methylthiotransferases",
				"children":[
				{
					"name":"ECTOBSL9_1781 hypothetical protein\tK06168 CDK5RAP1; tRNA-2-methylthio-N6-dimethylallyladenosine synthase [EC:2.8.4.3]"
				}
				]
			},
			{
				"name":"Methyltransferases",
				"children":[
				{
					"name":"ECTOBSL9_0858 tRNA (guanine-N7)-methyltransferase\tK03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33]"
				},
				{
					"name":"ECTOBSL9_1680 tRNA (guanine-N1)-methyltransferase\tK00554 trmD; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228]"
				},
				{
					"name":"ECTOBSL9_1049 tRNA modification GTPase MnmE\tK03650 mnmE; tRNA modification GTPase [EC:3.6.-.-]"
				},
				{
					"name":"ECTOBSL9_3197 RNA methyltransferase\tK15396 trmJ; tRNA (cytidine32\/uridine32-2'-O)-methyltransferase [EC:2.1.1.200]"
				},
				{
					"name":"ECTOBSL9_1185 rRNA methylase\tK03216 trmL; tRNA (cytidine\/uridine-2'-O-)-methyltransferase [EC:2.1.1.207]"
				}
				]
			},
			{
				"name":"Psudouridine synthases",
				"children":[
				{
					"name":"ECTOBSL9_2072 truA; tRNA pseudouridine synthase A\tK06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]"
				},
				{
					"name":"ECTOBSL9_0134 pseudouridine synthase\tK03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]"
				},
				{
					"name":"ECTOBSL9_2623 pseudouridine synthase\tK06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]"
				}
				]
			},
			{
				"name":"Thiolation factors",
				"children":[
				{
					"name":"ECTOBSL9_2699 mnmA; tRNA 2-thiouridylase\tK00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13]"
				},
				{
					"name":"ECTOBSL9_0830 potassium ABC transporter ATPase\tK14058 ttcA; tRNA 2-thiocytidine biosynthesis protein TtcA"
				},
				{
					"name":"ECTOBSL9_0289 SirA family protein\tK04085 tusA; tRNA 2-thiouridine synthesizing protein A [EC:2.8.1.-]"
				},
				{
					"name":"ECTOBSL9_3192 iscA; iron-sulfur cluster assembly protein\tK13628 iscA; iron-sulfur cluster assembly protein"
				},
				{
					"name":"ECTOBSL9_3087 cysteine desulfurase\tK04487 iscS; cysteine desulfurase [EC:2.8.1.7]"
				},
				{
					"name":"ECTOBSL9_3167 cysteine desulfurase\tK04487 iscS; cysteine desulfurase [EC:2.8.1.7]"
				},
				{
					"name":"ECTOBSL9_3194 cysteine desulfurase\tK04487 iscS; cysteine desulfurase [EC:2.8.1.7]"
				},
				{
					"name":"ECTOBSL9_3179 glycine cleavage system protein T\tK06980 ygfZ; tRNA-modifying protein YgfZ"
				}
				]
			},
			{
				"name":"KEOPS\/EKC complex"
			},
			{
				"name":"Other tRNA modification factors",
				"children":[
				{
					"name":"ECTOBSL9_1160 gidA; tRNA uridine 5-carboxymethylaminomethyl modification protein\tK03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme"
				},
				{
					"name":"ECTOBSL9_1917 tRNA dimethylallyltransferase\tK00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]"
				},
				{
					"name":"ECTOBSL9_3203 S-adenosylmethionine tRNA ribosyltransferase\tK07568 queA; S-adenosylmethionine:tRNA ribosyltransferase-isomerase [EC:2.4.99.17]"
				},
				{
					"name":"ECTOBSL9_0341 7-cyano-7-deazaguanine synthase\tK06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20]"
				},
				{
					"name":"ECTOBSL9_1669 6-pyruvoyl tetrahydrobiopterin synthase\tK01737 queD; 6-pyruvoyltetrahydropterin\/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50]"
				},
				{
					"name":"ECTOBSL9_0342 7-carboxy-7-deazaguanine synthase\tK10026 queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3]"
				},
				{
					"name":"ECTOBSL9_3210 7-cyano-7-deazaguanine reductase\tK09457 queF; 7-cyano-7-deazaguanine reductase [EC:1.7.1.13]"
				},
				{
					"name":"ECTOBSL9_1912 epoxyqueuosine reductase\tK18979 queG; epoxyqueuosine reductase [EC:1.17.99.6]"
				},
				{
					"name":"ECTOBSL9_3202 tgt; queuine tRNA-ribosyltransferase\tK00773 tgt; queuine tRNA-ribosyltransferase [EC:2.4.2.29]"
				},
				{
					"name":"ECTOBSL9_2455 tRNA(Ile)-lysidine synthetase\tK04075 tilS; tRNA(Ile)-lysidine synthase [EC:6.3.4.19]"
				},
				{
					"name":"ECTOBSL9_1259 hypothetical protein\tK06957 tmcA; tRNA(Met) cytidine acetyltransferase [EC:2.3.1.193]"
				},
				{
					"name":"ECTOBSL9_2622 glycoprotease\tK14742 tsaB; tRNA threonylcarbamoyladenosine biosynthesis protein TsaB"
				},
				{
					"name":"ECTOBSL9_0889 tRNA threonylcarbamoyladenosine biosynthesis protein RimN\tK07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]"
				},
				{
					"name":"ECTOBSL9_0539 UGMP family protein\tK25706 tsaD; tRNA N6-adenosine threonylcarbamoyltransferase [EC:2.3.1.234]"
				},
				{
					"name":"ECTOBSL9_1914 ATPase\tK06925 tsaE; tRNA threonylcarbamoyladenosine biosynthesis protein TsaE"
				},
				{
					"name":"ECTOBSL9_0842 MoeB\tK22132 tcdA; tRNA threonylcarbamoyladenosine dehydratase"
				}
				]
			}
			]
		},
		{
			"name":"tRNA degradation factors",
			"children":[
			{
				"name":"ECTOBSL9_0132 polynucleotide phosphorylase\/polyadenylase\tK00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]"
			}
			]
		}
		]
	}
	]
}