{
	"name":"eca01002",
	"children":[
	{
		"name":"Aspartic peptidases",
		"children":[
		{
			"name":"Family A1: pepsin family"
		},
		{
			"name":"Family A2: retropepsin family"
		},
		{
			"name":"Family A5: thermopsin family"
		},
		{
			"name":"Family A8: signal peptidase II family",
			"children":[
			{
				"name":"ECA3875 lspA; lipoprotein signal peptidase\tK03101 lspA; signal peptidase II [EC:3.4.23.36]"
			}
			]
		},
		{
			"name":"Family A22: presenilin family"
		},
		{
			"name":"Family A24: type IV prepilin peptidase family",
			"children":[
			{
				"name":"ECA0543 pilU; putative prepilin peptidase\tK02654 pilD; leader peptidase (prepilin peptidase) \/ N-methyltransferase [EC:3.4.23.43 2.1.1.-]"
			},
			{
				"name":"ECA3098 outO; type 4 prepilin-like proteins leader peptide processing enzyme\tK02464 gspO; general secretion pathway protein O [EC:3.4.23.43 2.1.1.-]"
			},
			{
				"name":"ECA0787 putative membrane protein\tK02278 cpaA; prepilin peptidase CpaA [EC:3.4.23.43]"
			}
			]
		},
		{
			"name":"Family A25: gpr protease family"
		},
		{
			"name":"Family A26: omptin family"
		},
		{
			"name":"Family A28"
		},
		{
			"name":"Family A31: HybD endopeptidase family",
			"children":[
			{
				"name":"ECA1229 hybD; hydrogenase 2 maturation protease\tK03605 hyaD; hydrogenase maturation protease [EC:3.4.23.-]"
			},
			{
				"name":"ECA1237 hycI; hydrogenase 3 maturation protease\tK08315 hycI; hydrogenase 3 maturation protease [EC:3.4.23.51]"
			}
			]
		},
		{
			"name":"Family A36"
		}
		]
	},
	{
		"name":"Cysteine peptidases",
		"children":[
		{
			"name":"Family C1: papain family"
		},
		{
			"name":"Family C2: calpain family"
		},
		{
			"name":"Family C3: picornain family"
		},
		{
			"name":"Family C4: NIa protease family"
		},
		{
			"name":"Family C5"
		},
		{
			"name":"Family C9"
		},
		{
			"name":"Family C10: streptopain family"
		},
		{
			"name":"Family C11: clostripain family"
		},
		{
			"name":"Family C12: ubiquitin C-terminal hydrolase family"
		},
		{
			"name":"Family C13: legumain family"
		},
		{
			"name":"Family C14: caspase family"
		},
		{
			"name":"Family C15: pyroglutamyl peptidase I family",
			"children":[
			{
				"name":"ECA1354 pcp; pyrrolidone-carboxylate peptidase\tK01304 PGPEP1; pyroglutamyl-peptidase [EC:3.4.19.3]"
			}
			]
		},
		{
			"name":"Family C16"
		},
		{
			"name":"Family C19: ubiquitin-specific protease family"
		},
		{
			"name":"Family C25: gingipain family"
		},
		{
			"name":"Family C26: gamma-glutamyl hydrolase family",
			"children":[
			{
				"name":"ECA3005 putative glutamine amidotransferase\tK01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]"
			},
			{
				"name":"ECA3208 guaA; GMP synthase [glutamine-hydrolyzing]\tK01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]"
			}
			]
		},
		{
			"name":"Family C27"
		},
		{
			"name":"Family C30"
		},
		{
			"name":"Family C37"
		},
		{
			"name":"Family C39"
		},
		{
			"name":"Family C40",
			"children":[
			{
				"name":"ECA2735 spr; lipoprotein\tK13694 mepS; murein DD-endopeptidase \/ murein LD-carboxypeptidase [EC:3.4.-.- 3.4.17.13]"
			},
			{
				"name":"ECA1926 putative exported protein\tK19303 mepH; murein DD-endopeptidase [EC:3.4.-.-]"
			},
			{
				"name":"ECA1835 nlpC; probable lipoprotein\tK13695 nlpC; probable lipoprotein NlpC"
			}
			]
		},
		{
			"name":"Family C44",
			"children":[
			{
				"name":"ECA3052 purF; amidophosphoribosyltransferase\tK00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]"
			},
			{
				"name":"ECA0312 gltB; glutamate synthase [NADPH] large chain\tK00265 gltB; glutamate synthase (NADPH) large chain [EC:1.4.1.13]"
			},
			{
				"name":"ECA4508 glmS; glucosamine--fructose-6-phosphate aminotransferase [isomerizing]\tK00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]"
			},
			{
				"name":"ECA1323 asnB; asparagine synthetase B [glutamine-hydrolyzing]\tK01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]"
			}
			]
		},
		{
			"name":"Family C45"
		},
		{
			"name":"Family C46: hedgehog family"
		},
		{
			"name":"Family C47: staphopain family"
		},
		{
			"name":"Family C48: Ulp1 endopeptidase family"
		},
		{
			"name":"Family C50: separase family"
		},
		{
			"name":"Family C54: Aut2 peptidase family"
		},
		{
			"name":"Family C55: YopJ protease family"
		},
		{
			"name":"Family C56: PfpI endopeptidase family",
			"children":[
			{
				"name":"ECA1135 thiJ; 4-methyl-5b-hydroxyethyl)-thiazole monophosphate biosynthesis protein\tK03152 thiJ; protein deglycase [EC:3.5.1.124]"
			}
			]
		},
		{
			"name":"Family C57: vaccinia virus I7 peptidase family"
		},
		{
			"name":"Family C58"
		},
		{
			"name":"Family C59"
		},
		{
			"name":"Family C60"
		},
		{
			"name":"Family C63"
		},
		{
			"name":"Family C64"
		},
		{
			"name":"Family C65"
		},
		{
			"name":"Family C67"
		},
		{
			"name":"Family C69"
		},
		{
			"name":"Family C70"
		},
		{
			"name":"Family C75"
		},
		{
			"name":"Family C76"
		},
		{
			"name":"Family C78"
		},
		{
			"name":"Family C79"
		},
		{
			"name":"Family C82",
			"children":[
			{
				"name":"ECA0821 putative exported protein\tK19236 ldtA_B_C_E; L,D-transpeptidase"
			},
			{
				"name":"ECA1865 conserved hypothetical protein\tK19236 ldtA_B_C_E; L,D-transpeptidase"
			},
			{
				"name":"ECA2546 putative exported protein\tK21470 ldtD; L,D-transpeptidase"
			},
			{
				"name":"ECA3471 putative exported protein\tK28919 dpaA; peptidoglycan meso-diaminopimelic acid protein amidase A [EC:3.4.-.-]"
			}
			]
		},
		{
			"name":"Family C83"
		},
		{
			"name":"Family C85"
		},
		{
			"name":"Family C86"
		},
		{
			"name":"Family C88"
		},
		{
			"name":"Family C89"
		},
		{
			"name":"Family C97"
		},
		{
			"name":"Family C98"
		},
		{
			"name":"Family C110"
		}
		]
	},
	{
		"name":"Glutamic peptidases",
		"children":[
		{
			"name":"Family G1"
		},
		{
			"name":"Family G4"
		},
		{
			"name":"Family G5: prenyl protease 2 family"
		}
		]
	},
	{
		"name":"Metallo peptidases",
		"children":[
		{
			"name":"Family M1",
			"children":[
			{
				"name":"ECA2539 pepN; aminopeptidase N\tK01256 pepN; aminopeptidase N [EC:3.4.11.2]"
			}
			]
		},
		{
			"name":"Family M2"
		},
		{
			"name":"Family M3",
			"children":[
			{
				"name":"ECA0055 prlC; oligopeptidase A\tK01414 prlC; oligopeptidase A [EC:3.4.24.70]"
			}
			]
		},
		{
			"name":"Family M4: thermolysin family"
		},
		{
			"name":"Family M5: mycolysin family"
		},
		{
			"name":"Family M6: immune inhibitor A family"
		},
		{
			"name":"Family M7: snapalysin family"
		},
		{
			"name":"Family M8: leishmanolysin family"
		},
		{
			"name":"Family M9"
		},
		{
			"name":"Family M10",
			"children":[
			{
				"name":"ECA2785 prtW; metalloprotease\tK01406 prtC; serralysin [EC:3.4.24.40]"
			}
			]
		},
		{
			"name":"Family M12: astacin\/adamalysin family"
		},
		{
			"name":"Family M13: neprilysin family"
		},
		{
			"name":"Family M14: carboxypeptidase A family"
		},
		{
			"name":"Family M15: zinc D-Ala-D-Ala carboxypeptidase family"
		},
		{
			"name":"Family M16: pitrilysin family",
			"children":[
			{
				"name":"ECA0994 ptrA; protease III precursor\tK01407 ptrA; protease III [EC:3.4.24.55]"
			},
			{
				"name":"ECA0879 putative zinc protease\tK07263 pqqL; zinc protease [EC:3.4.24.-]"
			}
			]
		},
		{
			"name":"Family M17: leucyl aminopeptidase family",
			"children":[
			{
				"name":"ECA0404 pepA; cytosolic aminopeptidase\tK01255 CARP; leucyl aminopeptidase [EC:3.4.11.1]"
			},
			{
				"name":"ECA3230 pepB; peptidase B\tK07751 pepB; PepB aminopeptidase [EC:3.4.11.23]"
			}
			]
		},
		{
			"name":"Family M18"
		},
		{
			"name":"Family M19: membrane dipeptidase family"
		},
		{
			"name":"Family M20",
			"children":[
			{
				"name":"ECA1291 dapE; succinyl-diaminopimelate desuccinylase\tK01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18]"
			},
			{
				"name":"ECA2448 pepT; peptidase T\tK01258 pepT; tripeptide aminopeptidase [EC:3.4.11.4]"
			},
			{
				"name":"ECA2802 peptidase\tK01258 pepT; tripeptide aminopeptidase [EC:3.4.11.4]"
			},
			{
				"name":"ECA3467 pepD; aminoacyl-histidine dipeptidase\tK01270 pepD; dipeptidase D [EC:3.4.13.-]"
			},
			{
				"name":"ECA4086 abgB; aminobenzoyl-glutamate utilization protein B\tK12941 abgB; aminobenzoyl-glutamate utilization protein B"
			},
			{
				"name":"ECA3490 amaB; N-carbamoyl-L-amino acid hydrolase\tK02083 allC; allantoate deiminase [EC:3.5.3.9]"
			}
			]
		},
		{
			"name":"Family M23",
			"children":[
			{
				"name":"ECA2483 putative peptidase\tK19304 mepM; murein DD-endopeptidase [EC:3.4.24.-]"
			}
			]
		},
		{
			"name":"Family M24",
			"children":[
			{
				"name":"ECA1030 map; methionine aminopeptidase\tK01265 map; methionyl aminopeptidase [EC:3.4.11.18]"
			},
			{
				"name":"ECA0209 pepQ; proline dipeptidase\tK01271 pepQ; Xaa-Pro dipeptidase [EC:3.4.13.9]"
			},
			{
				"name":"ECA0459 pepP; proline aminopeptidase II\tK01262 pepP; Xaa-Pro aminopeptidase [EC:3.4.11.9]"
			}
			]
		},
		{
			"name":"Family M26"
		},
		{
			"name":"Family M27"
		},
		{
			"name":"Family M28: aminopeptidase Y family"
		},
		{
			"name":"Family M29: aminopeptidase T family"
		},
		{
			"name":"Family M32: carboxypeptidase Taq family"
		},
		{
			"name":"Family M34: anthrax lethal factor family"
		},
		{
			"name":"Family M35: deuterolysin family"
		},
		{
			"name":"Family M36: fungalysin family"
		},
		{
			"name":"Family M38: beta-aspartyl dipeptidase family"
		},
		{
			"name":"Family M41: FtsH endopeptidase family",
			"children":[
			{
				"name":"ECA0698 hflB; cell division protein\tK03798 ftsH; cell division protease FtsH [EC:3.4.24.-]"
			}
			]
		},
		{
			"name":"Family M42: glutamyl aminopeptidase family"
		},
		{
			"name":"Family M43: cytophagalysin family"
		},
		{
			"name":"Family M44"
		},
		{
			"name":"Family M48: Ste24 endopeptidase family",
			"children":[
			{
				"name":"ECA2427 htpX; heat shock protein\tK03799 htpX; heat shock protein HtpX [EC:3.4.24.-]"
			},
			{
				"name":"ECA3915 putative peptidase\tK07387 K07387; metalloprotease [EC:3.4.24.-]"
			},
			{
				"name":"ECA1259 putative exported protein\tK01423 bepA; beta-barrel assembly-enhancing protease [EC:3.4.-.-]"
			}
			]
		},
		{
			"name":"Family M49: dipeptidyl-peptidase III family"
		},
		{
			"name":"Family M50: S2P protease family",
			"children":[
			{
				"name":"ECA1038 ecfE; protease\tK11749 rseP; regulator of sigma E protease [EC:3.4.24.-]"
			},
			{
				"name":"ECA0803 putative membrane protein\tK16922 yydH; putative peptide zinc metalloprotease protein"
			}
			]
		},
		{
			"name":"Family M54"
		},
		{
			"name":"Family M55: DppA aminopeptidase family",
			"children":[
			{
				"name":"ECA0133 conserved hypothetical protein\tK16203 dppA1; D-amino peptidase [EC:3.4.11.-]"
			}
			]
		},
		{
			"name":"Family M56"
		},
		{
			"name":"Family M67"
		},
		{
			"name":"Family M72"
		},
		{
			"name":"Family M73"
		},
		{
			"name":"Family M74",
			"children":[
			{
				"name":"ECA3068 mepA; penicillin-insensitive murein endopeptidase\tK07261 mepA; penicillin-insensitive murein DD-endopeptidase [EC:3.4.24.-]"
			}
			]
		},
		{
			"name":"Family M80"
		},
		{
			"name":"Family M82"
		},
		{
			"name":"Family M85"
		},
		{
			"name":"Family M88"
		},
		{
			"name":"Family M90",
			"children":[
			{
				"name":"ECA1680 conserved hypothetical protein\tK09933 mtfA; MtfA peptidase"
			}
			]
		},
		{
			"name":"Family M98"
		}
		]
	},
	{
		"name":"Asparagine peptide lyases",
		"children":[
		{
			"name":"Family N1"
		},
		{
			"name":"Family N8"
		}
		]
	},
	{
		"name":"Mixed peptidases",
		"children":[
		{
			"name":"Family P1: DmpA aminopeptidase family"
		},
		{
			"name":"Family P2"
		}
		]
	},
	{
		"name":"Serine peptidases",
		"children":[
		{
			"name":"Family S1: chymotrypsin family",
			"children":[
			{
				"name":"ECA2009 putative exported protease\tK04775 ydgD; protease YdgD [EC:3.4.21.-]"
			},
			{
				"name":"ECA3301 degP; protease Do\tK04771 degP; serine protease Do [EC:3.4.21.107]"
			},
			{
				"name":"ECA0303 degQ; exported protease\tK04772 degQ; serine protease DegQ [EC:3.4.21.-]"
			},
			{
				"name":"ECA0302 degS; exported protease\tK04691 hhoB; serine protease DegS [EC:3.4.21.-]"
			}
			]
		},
		{
			"name":"Family S3: togavirin family"
		},
		{
			"name":"Family S6"
		},
		{
			"name":"Family S7: flavivirin family"
		},
		{
			"name":"Family S8: subtilisin family"
		},
		{
			"name":"Family S9: prolyl oligopeptidase family",
			"children":[
			{
				"name":"ECA2476 ptrB; protease II\tK01354 ptrB; oligopeptidase B [EC:3.4.21.83]"
			}
			]
		},
		{
			"name":"Family S10"
		},
		{
			"name":"Family S11: D-Ala-D-Ala carboxypeptidase A family",
			"children":[
			{
				"name":"ECA1300 dacA; D-alanine carboxypeptidase\tK07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5\/6) [EC:3.4.16.4]"
			},
			{
				"name":"ECA2686 dacC; penicillin-binding protein 6\tK07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5\/6) [EC:3.4.16.4]"
			},
			{
				"name":"ECA2792 pbpG; penicillin-binding protein\tK07262 pbpG; serine-type D-Ala-D-Ala endopeptidase (penicillin-binding protein 7) [EC:3.4.21.-]"
			}
			]
		},
		{
			"name":"Family S12: D-Ala-D-Ala carboxypeptidase B family"
		},
		{
			"name":"Family S13: D-Ala-D-Ala peptidase C family",
			"children":[
			{
				"name":"ECA0694 dacD; penicillin-binding protein [includes: D-alanyl-D-alanine carboxypeptidase; D-alanyl-D-alanine-endopeptidase]\tK07259 dacB; serine-type D-Ala-D-Ala carboxypeptidase\/endopeptidase (penicillin-binding protein 4) [EC:3.4.16.4 3.4.21.-]"
			}
			]
		},
		{
			"name":"Family S14: ClpP endopeptidase family",
			"children":[
			{
				"name":"ECA1148 clpP; ATP-dependent Clp protease proteolytic subunit\tK01358 clpP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92]"
			}
			]
		},
		{
			"name":"Family S15"
		},
		{
			"name":"Family S16: lon protease family",
			"children":[
			{
				"name":"ECA1150 lon; ATP-dependent protease la\tK01338 lon; ATP-dependent Lon protease [EC:3.4.21.53]"
			},
			{
				"name":"ECA1749 conserved hypothetical protein\tK04770 lonH; Lon-like ATP-dependent protease [EC:3.4.21.-]"
			}
			]
		},
		{
			"name":"Family S21: assemblin family"
		},
		{
			"name":"Family S24: LexA family",
			"children":[
			{
				"name":"ECA0630 lexA; LexA repressor\tK01356 lexA; repressor LexA [EC:3.4.21.88]"
			}
			]
		},
		{
			"name":"Family S26: signal peptidase I family",
			"children":[
			{
				"name":"ECA3279 lepB; signal peptidase I\tK03100 lepB; signal peptidase I [EC:3.4.21.89]"
			}
			]
		},
		{
			"name":"Family S28"
		},
		{
			"name":"Family S31"
		},
		{
			"name":"Family S32"
		},
		{
			"name":"Family S33"
		},
		{
			"name":"Family S41: C-terminal processing peptidase family",
			"children":[
			{
				"name":"ECA2459 prc; tail-specific protease precursor\tK03797 E3.4.21.102; carboxyl-terminal processing protease [EC:3.4.21.102]"
			}
			]
		},
		{
			"name":"Family S45"
		},
		{
			"name":"Family S49: protease IV family",
			"children":[
			{
				"name":"ECA2339 sppA; protease IV\tK04773 sppA; protease IV [EC:3.4.21.-]"
			},
			{
				"name":"ECA2288 sohB; protease\tK04774 sohB; serine protease SohB [EC:3.4.21.-]"
			}
			]
		},
		{
			"name":"Family S50"
		},
		{
			"name":"Family S51"
		},
		{
			"name":"Family S53",
			"children":[
			{
				"name":"ECA1450 putative protease\tK08677 kscP; kumamolisin [EC:3.4.21.123]"
			}
			]
		},
		{
			"name":"Family S54: Rhomboid family",
			"children":[
			{
				"name":"ECA4138 glpG; putative membrane protein\tK02441 glpG; rhomboid protease GlpG [EC:3.4.21.105]"
			}
			]
		},
		{
			"name":"Family S55: SpoIVB peptidase family"
		},
		{
			"name":"Family S62"
		},
		{
			"name":"Family S66"
		},
		{
			"name":"Family S77: phage prohead processing peptidase family"
		},
		{
			"name":"Family S78"
		}
		]
	},
	{
		"name":"Threonine peptidases",
		"children":[
		{
			"name":"Family T1: proteasome family",
			"children":[
			{
				"name":"ECA4261 hslV; ATP-dependent protease (heat shock protein)\tK01419 hslV; ATP-dependent HslUV protease, peptidase subunit HslV [EC:3.4.25.2]"
			}
			]
		},
		{
			"name":"Family T2",
			"children":[
			{
				"name":"ECA0132 L-asparaginase\tK13051 ASRGL1; L-asparaginase \/ beta-aspartyl-peptidase [EC:3.5.1.1 3.4.19.5]"
			}
			]
		},
		{
			"name":"Family T3: gamma-glutamyltransferase family",
			"children":[
			{
				"name":"ECA4379 ggt; gamma-glutamyltranspeptidase\tK00681 ggt; gamma-glutamyltranspeptidase \/ glutathione hydrolase [EC:2.3.2.2 3.4.19.13]"
			},
			{
				"name":"ECA3497 putative gamma-glutamyltranspeptidase\tK22602 hpxW; oxamate amidohydrolase [EC:3.5.1.126]"
			}
			]
		}
		]
	},
	{
		"name":"Peptidases of unknown catalytic type",
		"children":[
		{
			"name":"Family U32",
			"children":[
			{
				"name":"ECA3193 putative protease\tK08303 prtC; U32 family peptidase [EC:3.4.-.-]"
			},
			{
				"name":"ECA0721 conserved hypothetical protein\tK24845 ubiV; 2-(all-trans-polyprenyl)phenol 6-hydroxylase (prephenate) UbiV [EC:1.97.1.15]"
			},
			{
				"name":"ECA0722 putative protease\tK24844 ubiU; 2-(all-trans-polyprenyl)phenol 6-hydroxylase (prephenate) UbiU [EC:1.97.1.15]"
			}
			]
		},
		{
			"name":"Family U62",
			"children":[
			{
				"name":"ECA0282 pmbA; putative modulator of DNA gyrase\tK03592 pmbA; PmbA protein"
			},
			{
				"name":"ECA1269 putative suppressor of the inhibitory activity of the carbon storage regulator CsrA\tK03592 pmbA; PmbA protein"
			},
			{
				"name":"ECA0273 tldD; putative modulator of DNA gyrase\tK03568 tldD; TldD protein"
			},
			{
				"name":"ECA1268 tldD; putative suppressor of the inhibitory activity of the carbon storage regulator CsrA\tK03568 tldD; TldD protein"
			}
			]
		}
		]
	},
	{
		"name":"Peptidase inhibitors",
		"children":[
		{
			"name":"Family I1: Kazal family"
		},
		{
			"name":"Family I2: Kunitz - BPTI family"
		},
		{
			"name":"Family I4: serpin family"
		},
		{
			"name":"Family I11: ecotin family"
		},
		{
			"name":"Family I17: WAP-type family"
		},
		{
			"name":"Family I25: cystatin family"
		},
		{
			"name":"Family I27: calpastatin family"
		},
		{
			"name":"Family I32: IAP family"
		},
		{
			"name":"Family I34: IA3 family"
		},
		{
			"name":"Family I35: timp family"
		},
		{
			"name":"Family I39: alpha2M family"
		},
		{
			"name":"Family I47: latexin family"
		},
		{
			"name":"Family I49: proSAAS family"
		},
		{
			"name":"Family I51: IC family"
		},
		{
			"name":"Family I57: staphostatin B family"
		},
		{
			"name":"Family I63"
		},
		{
			"name":"Family I80"
		},
		{
			"name":"Family I87",
			"children":[
			{
				"name":"ECA3931 hflC; putative phage-related protein\tK04087 hflC; modulator of FtsH protease HflC"
			},
			{
				"name":"ECA3932 hflK; putative phage-related protein\tK04088 hflK; modulator of FtsH protease HflK"
			}
			]
		},
		{
			"name":"Family I93"
		}
		]
	}
	]
}