{
	"name":"ecj03009",
	"children":[
	{
		"name":"Eukaryotic type",
		"children":[
		{
			"name":"Sno RNPs",
			"children":[
			{
				"name":"Box C\/D snoRNPs"
			},
			{
				"name":"Box H\/ACA snoRNPs"
			}
			]
		},
		{
			"name":"90S particles",
			"children":[
			{
				"name":"U3 small nucleolar RNA-associated proteins"
			},
			{
				"name":"Helicases"
			},
			{
				"name":"GTPase"
			},
			{
				"name":"RNase",
				"children":[
				{
					"name":"JW2551 rnc; RNase III\tK03685 rnc; ribonuclease III [EC:3.1.26.3]"
				}
				]
			},
			{
				"name":"Kinase"
			},
			{
				"name":"Other 90S particles"
			}
			]
		},
		{
			"name":"Pre-40S particles",
			"children":[
			{
				"name":"Kinases"
			},
			{
				"name":"Export and cytoplasmic maturation factors"
			},
			{
				"name":"Other pre-40S particles"
			}
			]
		},
		{
			"name":"Pre-60S particles",
			"children":[
			{
				"name":"Helicases"
			},
			{
				"name":"GTPases"
			},
			{
				"name":"RNases",
				"children":[
				{
					"name":"JW5740 orn; oligoribonuclease\tK13288 orn; oligoribonuclease [EC:3.1.-.-]"
				},
				{
					"name":"RNase MRP"
				}
				]
			},
			{
				"name":"Kinases"
			},
			{
				"name":"Export and cytoplasmic maturation factors"
			},
			{
				"name":"55LCC heterohexameric ATPase complex"
			},
			{
				"name":"5-FMC complex"
			},
			{
				"name":"Ribosome quality control proteins"
			},
			{
				"name":"Other pre-60S particles"
			}
			]
		},
		{
			"name":"Other ribosome biogenesis factors",
			"children":[
			{
				"name":"JW2550 era; membrane-associated, 16S rRNA-binding GTPase\tK03595 era; GTPase"
			},
			{
				"name":"JW3150 obgE; GTPase involved in cell partioning and DNA repair\tK03979 obgE; GTPase [EC:3.6.5.-]"
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic type",
		"children":[
		{
			"name":"Sno RNPs",
			"children":[
			{
				"name":"Box C\/D snoRNPs"
			},
			{
				"name":"Box H\/ACA snoRNPs"
			}
			]
		},
		{
			"name":"rRNA transcription factors",
			"children":[
			{
				"name":"JW0141 dksA; transcriptional regulator of rRNA transcription, DnaK suppressor protein\tK06204 dksA; RNA polymerase-binding transcription factor"
			},
			{
				"name":"JW3138 nusA; transcription termination\/antitermination L factor\tK02600 nusA; transcription termination\/antitermination protein NusA"
			},
			{
				"name":"JW0406 nusB; transcription antitermination protein\tK03625 nusB; transcription antitermination protein NusB"
			},
			{
				"name":"JW3945 nusG; transcription termination factor\tK02601 nusG; transcription termination\/antitermination protein NusG"
			}
			]
		},
		{
			"name":"rRNA modification factors",
			"children":[
			{
				"name":"16S rRNA modification factors",
				"children":[
				{
					"name":"JW2171 rsuA; 16S rRNA pseudouridylate 516 synthase\tK06183 rsuA; 16S rRNA pseudouridine516 synthase [EC:5.4.99.19]"
				},
				{
					"name":"JW0050 ksgA; S-adenosylmethionine-6-N',N'-adenosyl (rRNA) dimethyltransferase\tK02528 ksgA; 16S rRNA (adenine1518-N6\/adenine1519-N6)-dimethyltransferase [EC:2.1.1.182]"
				},
				{
					"name":"JW3250 rsmB; 16S rRNA m5C967 methyltransferase, S-adenosyl-L-methionine-dependent\tK03500 rsmB; 16S rRNA (cytosine967-C5)-methyltransferase [EC:2.1.1.176]"
				},
				{
					"name":"JW4333 rsmC; 16S RNA m2G1207 methylase\tK00564 rsmC; 16S rRNA (guanine1207-N2)-methyltransferase [EC:2.1.1.172]"
				},
				{
					"name":"JW3430 yhhF; predicted methyltransferase\tK08316 rsmD; 16S rRNA (guanine966-N2)-methyltransferase [EC:2.1.1.171]"
				},
				{
					"name":"JW2913 yggJ; hypothetical protein\tK09761 rsmE; 16S rRNA (uracil1498-N3)-methyltransferase [EC:2.1.1.193]"
				},
				{
					"name":"JW5301 yebU; predicted methyltransferase\tK11392 rsmF; 16S rRNA (cytosine1407-C5)-methyltransferase [EC:2.1.1.178]"
				},
				{
					"name":"JW3718 gidB; methyltransferase, glucose-inhibited cell-division protein\tK03501 gidB; 16S rRNA (guanine527-N7)-methyltransferase [EC:2.1.1.170]"
				},
				{
					"name":"JW0080 mraW; S-adenosyl-dependent methyltransferase activity on membrane-located substrates\tK03438 mraW; 16S rRNA (cytosine1402-N4)-methyltransferase [EC:2.1.1.199]"
				},
				{
					"name":"JW3115 yraL; predicted methyltransferase\tK07056 rsmI; 16S rRNA (cytidine1402-2'-O)-methyltransferase [EC:2.1.1.198]"
				},
				{
					"name":"JW5672 yhiQ; predicted SAM-dependent methyltransferase\tK15984 rsmJ; 16S rRNA (guanine1516-N2)-methyltransferase [EC:2.1.1.242]"
				}
				]
			},
			{
				"name":"23S rRNA modification factors",
				"children":[
				{
					"name":"JW1811 rrmA; 23S rRNA m1G745 methyltransferase\tK00563 rlmA1; 23S rRNA (guanine745-N1)-methyltransferase [EC:2.1.1.187]"
				},
				{
					"name":"JW4138 rlmB; 23S rRNA (Gm2251)-methyltransferase\tK03218 rlmB; 23S rRNA (guanosine2251-2'-O)-methyltransferase [EC:2.1.1.185]"
				},
				{
					"name":"JW3146 rrmJ; 23S rRNA methyltransferase\tK02427 rlmE; 23S rRNA (uridine2552-2'-O)-methyltransferase [EC:2.1.1.166]"
				},
				{
					"name":"JW5107 ybiN; predicted SAM-dependent methyltransferase\tK06970 rlmF; 23S rRNA (adenine1618-N6)-methyltransferase [EC:2.1.1.181]"
				},
				{
					"name":"JW5513 ygjO; predicted methyltransferase small domain\tK11391 rlmG; 23S rRNA (guanine1835-N2)-methyltransferase [EC:2.1.1.174]"
				},
				{
					"name":"JW0631 ybeA; conserved hypothetical protein\tK00783 rlmH; 23S rRNA (pseudouridine1915-N3)-methyltransferase [EC:2.1.1.177]"
				},
				{
					"name":"JW5898 yccW; predicted methyltransferase\tK06969 rlmI; 23S rRNA (cytosine1962-C5)-methyltransferase [EC:2.1.1.191]"
				},
				{
					"name":"JW3466 yhiR; predicted DNA (exogenous) processing protein\tK07115 rlmJ; 23S rRNA (adenine2030-N6)-methyltransferase [EC:2.1.1.266]"
				},
				{
					"name":"JW0931 ycbY; predicted methyltransferase\tK12297 rlmKL; 23S rRNA (guanine2069-N7)-methyltransferase \/ 23S rRNA (guanine2445-N2)-methyltransferase [EC:2.1.1.264 2.1.1.173]"
				},
				{
					"name":"JW2777 ygdE; predicted methyltransferase\tK06968 rlmM; 23S rRNA (cytidine2498-2'-O)-methyltransferase [EC:2.1.1.186]"
				},
				{
					"name":"JW2501 yfgB; hypothetical protein\tK06941 rlmN; 23S rRNA (adenine2503-C2)-methyltransferase [EC:2.1.1.192]"
				},
				{
					"name":"JW2756 rumA; 23S rRNA (uracil-5)-methyltransferase\tK03215 rumA; 23S rRNA (uracil1939-C5)-methyltransferase [EC:2.1.1.190]"
				},
				{
					"name":"JW0843 rumB; 23S rRNA m(5)U747 methyltransferase\tK03212 rumB; 23S rRNA (uracil747-C5)-methyltransferase [EC:2.1.1.189]"
				},
				{
					"name":"JW0057 rluA; pseudouridine synthase for 23S rRNA (position 746) and tRNAphe(position 32)\tK06177 rluA; tRNA pseudouridine32 synthase \/ 23S rRNA pseudouridine746 synthase [EC:5.4.99.28 5.4.99.29]"
				},
				{
					"name":"JW1261 rluB; 23S rRNA pseudouridylate synthase\tK06178 rluB; 23S rRNA pseudouridine2605 synthase [EC:5.4.99.22]"
				},
				{
					"name":"JW1072 rluC; 23S rRNA pseudouridylate synthase\tK06179 rluC; 23S rRNA pseudouridine955\/2504\/2580 synthase [EC:5.4.99.24]"
				},
				{
					"name":"JW2576 rluD; 23S rRNA pseudouridine synthase\tK06180 rluD; 23S rRNA pseudouridine1911\/1915\/1917 synthase [EC:5.4.99.23]"
				},
				{
					"name":"JW1121 ymfC; 23S rRNA pseudouridine synthase\tK06181 rluE; 23S rRNA pseudouridine2457 synthase [EC:5.4.99.20]"
				},
				{
					"name":"JW3982 yjbC; 23S rRNA pseudouridine synthase\tK06182 rluF; 23S rRNA pseudouridine2604 synthase [EC:5.4.99.21]"
				},
				{
					"name":"JW2565 yfiF; predicted methyltransferase\tK03214 yfiF; RNA methyltransferase, TrmH family [EC:2.1.1.-]"
				}
				]
			}
			]
		},
		{
			"name":"ribosomal protein modification factors",
			"children":[
			{
				"name":"JW4335 rimI; acetylase for 30S ribosomal subunit protein S18\tK03789 rimI; [ribosomal protein S18]-alanine N-acetyltransferase \/ [ribosomal protein L31]-L-lysine N-acetyltransferase [EC:2.3.1.266 2.3.1.338]"
			},
			{
				"name":"JW1053 rimJ; ribosomal-protein-S5-alanine N-acetyltransferase\tK03790 rimJ; [ribosomal protein S5]-alanine N-acetyltransferase [EC:2.3.1.267]"
			},
			{
				"name":"JW0836 rimK; ribosomal protein S6 modification protein\tK05844 rimK; ribosomal protein S6--L-glutamate ligase [EC:6.3.2.-]"
			},
			{
				"name":"JW1423 rimL; ribosomal-protein-L7\/L12-serine acetyltransferase\tK03817 rimL; ribosomal-protein-serine acetyltransferase [EC:2.3.1.-]"
			},
			{
				"name":"JW5413 rimM; 16S rRNA processing protein\tK02860 rimM; 16S rRNA processing protein RimM"
			},
			{
				"name":"JW0819 yliG; predicted SAM-dependent methyltransferase\tK14441 rimO; ribosomal protein S12 methylthiotransferase [EC:2.8.4.4]"
			},
			{
				"name":"JW0888 ycaO; conserved hypothetical protein\tK09136 ycaO; ribosomal protein S12 methylthiotransferase accessory factor"
			},
			{
				"name":"JW3227 prmA; methylase for 50S ribosomal subunit protein L11\tK02687 prmA; ribosomal protein L11 methyltransferase [EC:2.1.1.-]"
			},
			{
				"name":"JW5841 prmB; N5-glutamine methyltransferase\tK07320 prmB; ribosomal protein L3 glutamine methyltransferase [EC:2.1.1.298]"
			},
			{
				"name":"JW1114 ycfD; conserved hypothetical protein\tK18850 ycfD; 50S ribosomal protein L16 3-hydroxylase [EC:1.14.11.47]"
			}
			]
		},
		{
			"name":"rRNA processing factors",
			"children":[
			{
				"name":"JW2551 rnc; RNase III\tK03685 rnc; ribonuclease III [EC:3.1.26.3]"
			},
			{
				"name":"JW1071 rne; fused ribonucleaseE endoribonuclease and scaffold for formation of degradosome\tK08300 rne; ribonuclease E [EC:3.1.26.12]"
			},
			{
				"name":"JW3216 rng; ribonuclease G\tK08301 rng; ribonuclease G [EC:3.1.26.-]"
			},
			{
				"name":"JW2916 yqgF; predicted Holliday junction resolvase\tK07447 ruvX; putative pre-16S rRNA nuclease [EC:3.1.-.-]"
			}
			]
		},
		{
			"name":"rRNA helicases",
			"children":[
			{
				"name":"JW1337 dbpA; ATP-dependent RNA helicase specific for 23S rRNA\tK05591 dbpA; ATP-dependent RNA helicase DbpA [EC:5.6.2.6]"
			},
			{
				"name":"JW5531 deaD; ATP-dependent RNA helicase\tK05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7]"
			},
			{
				"name":"JW2560 srmB; ATP-dependent RNA helicase\tK05590 srmB; ATP-dependent RNA helicase SrmB [EC:5.6.2.7]"
			}
			]
		},
		{
			"name":"GTPases",
			"children":[
			{
				"name":"JW2550 era; membrane-associated, 16S rRNA-binding GTPase\tK03595 era; GTPase"
			},
			{
				"name":"JW4122 rsgA; ribosome small subunit-dependent GTPase A\tK06949 rsgA; ribosome biogenesis GTPase \/ thiamine phosphate phosphatase [EC:3.6.1.- 3.1.3.100]"
			},
			{
				"name":"JW5403 der; predicted GTP-binding protein\tK03977 engA; GTPase"
			},
			{
				"name":"JW3150 obgE; GTPase involved in cell partioning and DNA repair\tK03979 obgE; GTPase [EC:3.6.5.-]"
			},
			{
				"name":"JW4131 hflX; predicted GTPase\tK03665 hflX; GTPase"
			}
			]
		},
		{
			"name":"Other maturation factors",
			"children":[
			{
				"name":"JW3243 yrdC; dsRNA-binding protein\tK07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]"
			},
			{
				"name":"JW3625 spoT; bifunctional (p)ppGpp synthetase II and guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase\tK01139 spoT; GTP diphosphokinase \/ guanosine-3',5'-bis(diphosphate) 3'-diphosphatase [EC:2.7.6.5 3.1.7.2]"
			},
			{
				"name":"JW3136 rbfA; 30s ribosome binding factor\tK02834 rbfA; ribosome-binding factor A"
			},
			{
				"name":"JW5533 yhbC; conserved hypothetical protein\tK09748 rimP; ribosome maturation factor RimP"
			},
			{
				"name":"JW5070 ybcJ; predicted RNA-binding protein\tK14761 rlbA; ribosome-associated protein"
			},
			{
				"name":"JW5090 ybeB; hypothetical protein\tK09710 ybeB; ribosome-associated protein"
			},
			{
				"name":"JW0656 ybeY; conserved hypothetical protein\tK07042 ybeY; probable rRNA maturation factor"
			},
			{
				"name":"JW3147 yhbY; predicted RNA-binding protein\tK07574 yhbY; RNA-binding protein"
			},
			{
				"name":"JW3577 yibL; conserved hypothetical protein\tK14762 yibL; ribosome-associated protein"
			},
			{
				"name":"JW4193 yjgA; conserved hypothetical protein\tK09889 yjgA; ribosome-associated protein"
			},
			{
				"name":"JW0936 rmf; ribosome modulation factor\tK03812 rmf; ribosome modulation factor"
			},
			{
				"name":"JW3170 yhbH; predicted ribosome-associated, sigma 54 modulation protein\tK05808 hpf; ribosome hibernation promoting factor"
			},
			{
				"name":"JW2578 yfiA; cold shock protein associated with 30S ribosomal subunit\tK05809 raiA; ribosome-associated inhibitor A"
			},
			{
				"name":"JW5962 sra; 30S ribosomal subunit protein S22\tK02972 sra; stationary-phase-induced ribosome-associated protein"
			},
			{
				"name":"JW1194 ychF; predicted GTP-binding protein\tK06942 ychF; ribosome-binding ATPase"
			},
			{
				"name":"JW1074 yceD; conserved hypothetical protein\tK07040 yceD; DUF177 domain-containing protein"
			}
			]
		}
		]
	},
	{
		"name":"Related small nucleolar RNAs",
		"children":[
		{
			"name":"Box C\/D snoRNAs",
			"children":[
			{
				"name":"SnoRNAs involved in processing reactions"
			},
			{
				"name":"SnoRNAs act as guides for 2'-O-ribose methylation"
			}
			]
		},
		{
			"name":"Box H\/ACA snoRNAs",
			"children":[
			{
				"name":"SnoRNAs involved in processing reactions"
			},
			{
				"name":"SnoRNAs act as guides for pseudouridynation"
			}
			]
		},
		{
			"name":"Other snoRNA"
		}
		]
	}
	]
}