{
	"name":"eclo03009",
	"children":[
	{
		"name":"Eukaryotic type",
		"children":[
		{
			"name":"Sno RNPs",
			"children":[
			{
				"name":"Box C\/D snoRNPs"
			},
			{
				"name":"Box H\/ACA snoRNPs"
			}
			]
		},
		{
			"name":"90S particles",
			"children":[
			{
				"name":"U3 small nucleolar RNA-associated proteins"
			},
			{
				"name":"Helicases"
			},
			{
				"name":"GTPase"
			},
			{
				"name":"RNase",
				"children":[
				{
					"name":"ENC_36940 RNAse III\tK03685 rnc; ribonuclease III [EC:3.1.26.3]"
				}
				]
			},
			{
				"name":"Kinase"
			},
			{
				"name":"Other 90S particles"
			}
			]
		},
		{
			"name":"Pre-40S particles",
			"children":[
			{
				"name":"Kinases"
			},
			{
				"name":"Export and cytoplasmic maturation factors"
			},
			{
				"name":"Other pre-40S particles"
			}
			]
		},
		{
			"name":"Pre-60S particles",
			"children":[
			{
				"name":"Helicases"
			},
			{
				"name":"GTPases"
			},
			{
				"name":"RNases",
				"children":[
				{
					"name":"ENC_42640 Oligoribonuclease (3'->5' exoribonuclease)\tK13288 orn; oligoribonuclease [EC:3.1.-.-]"
				},
				{
					"name":"RNase MRP"
				}
				]
			},
			{
				"name":"Kinases"
			},
			{
				"name":"Export and cytoplasmic maturation factors"
			},
			{
				"name":"55LCC heterohexameric ATPase complex"
			},
			{
				"name":"5-FMC complex"
			},
			{
				"name":"Ribosome quality control proteins"
			},
			{
				"name":"Other pre-60S particles"
			}
			]
		},
		{
			"name":"Other ribosome biogenesis factors",
			"children":[
			{
				"name":"ENC_36950 GTP-binding protein Era\tK03595 era; GTPase"
			},
			{
				"name":"ENC_34200 Obg family GTPase CgtA\tK03979 obgE; GTPase [EC:3.6.5.-]"
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic type",
		"children":[
		{
			"name":"Sno RNPs",
			"children":[
			{
				"name":"Box C\/D snoRNPs"
			},
			{
				"name":"Box H\/ACA snoRNPs"
			}
			]
		},
		{
			"name":"rRNA transcription factors",
			"children":[
			{
				"name":"ENC_46600 RNA polymerase-binding protein DksA\tK06204 dksA; RNA polymerase-binding transcription factor"
			},
			{
				"name":"ENC_34070 transcription termination factor NusA\/transcription termination factor NusA, C-terminal duplication\tK02600 nusA; transcription termination\/antitermination protein NusA"
			},
			{
				"name":"ENC_01440 transcription antitermination protein nusG\tK02601 nusG; transcription termination\/antitermination protein NusG"
			}
			]
		},
		{
			"name":"rRNA modification factors",
			"children":[
			{
				"name":"16S rRNA modification factors",
				"children":[
				{
					"name":"ENC_39850 ribosomal small subunit pseudouridine synthase A\tK06183 rsuA; 16S rRNA pseudouridine516 synthase [EC:5.4.99.19]"
				},
				{
					"name":"ENC_45660 dimethyladenosine transferase\tK02528 ksgA; 16S rRNA (adenine1518-N6\/adenine1519-N6)-dimethyltransferase [EC:2.1.1.182]"
				},
				{
					"name":"ENC_25030 16S rRNA m(5)C-967 methyltransferase\tK03500 rsmB; 16S rRNA (cytosine967-C5)-methyltransferase [EC:2.1.1.176]"
				},
				{
					"name":"ENC_44920 16S rRNA m(2)G 1207 methyltransferase\tK00564 rsmC; 16S rRNA (guanine1207-N2)-methyltransferase [EC:2.1.1.172]"
				},
				{
					"name":"ENC_26570 16S rRNA m(2)G-966 methyltransferase\tK08316 rsmD; 16S rRNA (guanine966-N2)-methyltransferase [EC:2.1.1.171]"
				},
				{
					"name":"ENC_31960 16S rRNA m(3)U-1498 methyltransferase\tK09761 rsmE; 16S rRNA (uracil1498-N3)-methyltransferase [EC:2.1.1.193]"
				},
				{
					"name":"ENC_06590 16S rRNA m(5)C-1407 methyltransferase\tK11392 rsmF; 16S rRNA (cytosine1407-C5)-methyltransferase [EC:2.1.1.178]"
				},
				{
					"name":"ENC_45940 S-adenosyl-methyltransferase MraW\tK03438 mraW; 16S rRNA (cytosine1402-N4)-methyltransferase [EC:2.1.1.199]"
				},
				{
					"name":"ENC_33840 conserved hypothetical protein TIGR00096\tK07056 rsmI; 16S rRNA (cytidine1402-2'-O)-methyltransferase [EC:2.1.1.198]"
				}
				]
			},
			{
				"name":"23S rRNA modification factors",
				"children":[
				{
					"name":"ENC_06740 23S rRNA m(1)G-745 methyltransferase\tK00563 rlmA1; 23S rRNA (guanine745-N1)-methyltransferase [EC:2.1.1.187]"
				},
				{
					"name":"ENC_42810 23S rRNA Gm-2251 2'-O-methyltransferase\tK03218 rlmB; 23S rRNA (guanosine2251-2'-O)-methyltransferase [EC:2.1.1.185]"
				},
				{
					"name":"ENC_34140 23S rRNA Um-2552 2'-O-methyltransferase\tK02427 rlmE; 23S rRNA (uridine2552-2'-O)-methyltransferase [EC:2.1.1.166]"
				},
				{
					"name":"ENC_19280 23S rRNA m(6)A-1618 methyltransferase\tK06970 rlmF; 23S rRNA (adenine1618-N6)-methyltransferase [EC:2.1.1.181]"
				},
				{
					"name":"ENC_33430 16S rRNA m(2)G 1207 methyltransferase\/23S rRNA m(2)G-1835 methyltransferase\tK11391 rlmG; 23S rRNA (guanine1835-N2)-methyltransferase [EC:2.1.1.174]"
				},
				{
					"name":"ENC_16600 SAM-dependent methyltransferase\/23S rRNA m(5)C-1962 methyltransferase\tK06969 rlmI; 23S rRNA (cytosine1962-C5)-methyltransferase [EC:2.1.1.191]"
				},
				{
					"name":"ENC_27070 Protein involved in catabolism of external DNA\tK07115 rlmJ; 23S rRNA (adenine2030-N6)-methyltransferase [EC:2.1.1.266]"
				},
				{
					"name":"ENC_16820 23S rRNA m(2)G-2445 methyltransferase\tK12297 rlmKL; 23S rRNA (guanine2069-N7)-methyltransferase \/ 23S rRNA (guanine2445-N2)-methyltransferase [EC:2.1.1.264 2.1.1.173]"
				},
				{
					"name":"ENC_30440 Predicted SAM-dependent methyltransferase\tK06968 rlmM; 23S rRNA (cytidine2498-2'-O)-methyltransferase [EC:2.1.1.186]"
				},
				{
					"name":"ENC_37450 23S rRNA m(2)A-2503 methyltransferase\tK06941 rlmN; 23S rRNA (adenine2503-C2)-methyltransferase [EC:2.1.1.192]"
				},
				{
					"name":"ENC_30260 23S rRNA m(5)U-1939 methyltransferase\tK03215 rumA; 23S rRNA (uracil1939-C5)-methyltransferase [EC:2.1.1.190]"
				},
				{
					"name":"ENC_11450 Pseudouridylate synthases, 23S RNA-specific\tK06177 rluA; tRNA pseudouridine32 synthase \/ 23S rRNA pseudouridine746 synthase [EC:5.4.99.28 5.4.99.29]"
				},
				{
					"name":"ENC_45710 ribosomal large subunit pseudouridine synthase A\tK06177 rluA; tRNA pseudouridine32 synthase \/ 23S rRNA pseudouridine746 synthase [EC:5.4.99.28 5.4.99.29]"
				},
				{
					"name":"ENC_08280 ribosomal large subunit pseudouridine synthase B\tK06178 rluB; 23S rRNA pseudouridine2605 synthase [EC:5.4.99.22]"
				},
				{
					"name":"ENC_04520 ribosomal large subunit pseudouridine synthase F\tK06182 rluF; 23S rRNA pseudouridine2604 synthase [EC:5.4.99.21]"
				}
				]
			}
			]
		},
		{
			"name":"ribosomal protein modification factors",
			"children":[
			{
				"name":"ENC_44940 [SSU ribosomal protein S18P]-alanine acetyltransferase\tK03789 rimI; [ribosomal protein S18]-alanine N-acetyltransferase \/ [ribosomal protein L31]-L-lysine N-acetyltransferase [EC:2.3.1.266 2.3.1.338]"
			},
			{
				"name":"ENC_15780 [SSU ribosomal protein S5P]-alanine acetyltransferase\tK03790 rimJ; [ribosomal protein S5]-alanine N-acetyltransferase [EC:2.3.1.267]"
			},
			{
				"name":"ENC_18560 SSU ribosomal protein S6P modification protein\tK05844 rimK; ribosomal protein S6--L-glutamate ligase [EC:6.3.2.-]"
			},
			{
				"name":"ENC_28070 16S rRNA processing protein RimM\tK02860 rimM; 16S rRNA processing protein RimM"
			},
			{
				"name":"ENC_17790 uncharacterized domain\tK09136 ycaO; ribosomal protein S12 methylthiotransferase accessory factor"
			},
			{
				"name":"ENC_35080 [LSU ribosomal protein L11P]-lysine N-methyltransferase\tK02687 prmA; ribosomal protein L11 methyltransferase [EC:2.1.1.-]"
			},
			{
				"name":"ENC_15090 Uncharacterized conserved protein\tK18850 ycfD; 50S ribosomal protein L16 3-hydroxylase [EC:1.14.11.47]"
			},
			{
				"name":"ENC_44350 Uncharacterized conserved protein\tK18850 ycfD; 50S ribosomal protein L16 3-hydroxylase [EC:1.14.11.47]"
			}
			]
		},
		{
			"name":"rRNA processing factors",
			"children":[
			{
				"name":"ENC_36940 RNAse III\tK03685 rnc; ribonuclease III [EC:3.1.26.3]"
			},
			{
				"name":"ENC_34910 RNAse G\tK08301 rng; ribonuclease G [EC:3.1.26.-]"
			},
			{
				"name":"ENC_31990 conserved hypothetical protein TIGR00250\tK07447 ruvX; putative pre-16S rRNA nuclease [EC:3.1.-.-]"
			}
			]
		},
		{
			"name":"rRNA helicases",
			"children":[
			{
				"name":"ENC_34000 ATP-dependent RNA helicase CsdA\tK05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7]"
			},
			{
				"name":"ENC_36840 Superfamily II DNA and RNA helicases\tK05590 srmB; ATP-dependent RNA helicase SrmB [EC:5.6.2.7]"
			}
			]
		},
		{
			"name":"GTPases",
			"children":[
			{
				"name":"ENC_36950 GTP-binding protein Era\tK03595 era; GTPase"
			},
			{
				"name":"ENC_34200 Obg family GTPase CgtA\tK03979 obgE; GTPase [EC:3.6.5.-]"
			}
			]
		},
		{
			"name":"Other maturation factors",
			"children":[
			{
				"name":"ENC_34050 ribosome-binding factor A\tK02834 rbfA; ribosome-binding factor A"
			},
			{
				"name":"ENC_34080 Uncharacterized protein conserved in bacteria\tK09748 rimP; ribosome maturation factor RimP"
			},
			{
				"name":"ENC_22190 Uncharacterized conserved protein\tK14761 rlbA; ribosome-associated protein"
			},
			{
				"name":"ENC_20580 conserved hypothetical protein TIGR00043\tK07042 ybeY; probable rRNA maturation factor"
			},
			{
				"name":"ENC_34150 conserved hypothetical protein TIGR00253\tK07574 yhbY; RNA-binding protein"
			},
			{
				"name":"ENC_47660 Protein of unknown function (DUF2810).\tK14762 yibL; ribosome-associated protein"
			},
			{
				"name":"ENC_43420 Uncharacterized protein conserved in bacteria\tK09889 yjgA; ribosome-associated protein"
			},
			{
				"name":"ENC_34400 ribosomal subunit interface protein\tK05808 hpf; ribosome hibernation promoting factor"
			},
			{
				"name":"ENC_27940 ribosomal subunit interface protein\tK05809 raiA; ribosome-associated inhibitor A"
			},
			{
				"name":"ENC_09950 SSU ribosomal protein S22P\tK02972 sra; stationary-phase-induced ribosome-associated protein"
			},
			{
				"name":"ENC_07500 GTP-binding protein YchF\tK06942 ychF; ribosome-binding ATPase"
			},
			{
				"name":"ENC_15520 Predicted metal-binding, possibly nucleic acid-binding protein\tK07040 yceD; DUF177 domain-containing protein"
			}
			]
		}
		]
	},
	{
		"name":"Related small nucleolar RNAs",
		"children":[
		{
			"name":"Box C\/D snoRNAs",
			"children":[
			{
				"name":"SnoRNAs involved in processing reactions"
			},
			{
				"name":"SnoRNAs act as guides for 2'-O-ribose methylation"
			}
			]
		},
		{
			"name":"Box H\/ACA snoRNAs",
			"children":[
			{
				"name":"SnoRNAs involved in processing reactions"
			},
			{
				"name":"SnoRNAs act as guides for pseudouridynation"
			}
			]
		},
		{
			"name":"Other snoRNA"
		}
		]
	}
	]
}