{
	"name":"ecm02044",
	"children":[
	{
		"name":"Type I secretion system",
		"children":[
		{
			"name":"alpha-Hemolysin\/cyclolysin transporter",
			"children":[
			{
				"name":"EcSMS35_3330 tolC; outer membrane protein TolC\tK12340 tolC; outer membrane protein"
			}
			]
		},
		{
			"name":"RTX toxin transporter",
			"children":[
			{
				"name":"EcSMS35_3330 tolC; outer membrane protein TolC\tK12340 tolC; outer membrane protein"
			}
			]
		},
		{
			"name":"Multiple protein transporter",
			"children":[
			{
				"name":"EcSMS35_3330 tolC; outer membrane protein TolC\tK12340 tolC; outer membrane protein"
			}
			]
		},
		{
			"name":"Adhesin protein transporter"
		},
		{
			"name":"RaxAB-RaxC type I secretion system protein",
			"children":[
			{
				"name":"EcSMS35_3330 tolC; outer membrane protein TolC\tK12340 tolC; outer membrane protein"
			}
			]
		}
		]
	},
	{
		"name":"Type II secretion system",
		"children":[
		{
			"name":"General secretion pathway protein",
			"children":[
			{
				"name":"EcSMS35_3248 gspC; general secretion pathway protein GspC\tK02452 gspC; general secretion pathway protein C"
			},
			{
				"name":"EcSMS35_3247 gspD; general secretion pathway protein GspD\tK02453 gspD; general secretion pathway protein D"
			},
			{
				"name":"EcSMS35_3246 gspE; general secretory pathway protein GspE\tK02454 gspE; general secretion pathway protein E [EC:7.4.2.8]"
			},
			{
				"name":"EcSMS35_3245 gspF; general secretion pathway protein GspF\tK02455 gspF; general secretion pathway protein F"
			},
			{
				"name":"EcSMS35_3244 gspG; general secretion pathway protein GspG\tK02456 gspG; general secretion pathway protein G"
			},
			{
				"name":"EcSMS35_3243 gspH; general secretion pathway protein GspH\tK02457 gspH; general secretion pathway protein H"
			},
			{
				"name":"EcSMS35_3242 gspI; general secretion pathway protein GspI\tK02458 gspI; general secretion pathway protein I"
			},
			{
				"name":"EcSMS35_3241 gspJ; general secretion pathway protein GspJ\tK02459 gspJ; general secretion pathway protein J"
			},
			{
				"name":"EcSMS35_3240 gspK; general secretion pathway protein GspK\tK02460 gspK; general secretion pathway protein K"
			},
			{
				"name":"EcSMS35_3239 gspL; general secretion pathway protein GspL\tK02461 gspL; general secretion pathway protein L"
			},
			{
				"name":"EcSMS35_3238 gspM; general secretion pathway protein GspM\tK02462 gspM; general secretion pathway protein M"
			},
			{
				"name":"EcSMS35_3250 pppA; leader peptidase PppA\tK02654 pilD; leader peptidase (prepilin peptidase) \/ N-methyltransferase [EC:3.4.23.43 2.1.1.-]"
			}
			]
		},
		{
			"name":"Pilin secretion\/fimbrial assembly protein",
			"children":[
			{
				"name":"EcSMS35_3250 pppA; leader peptidase PppA\tK02654 pilD; leader peptidase (prepilin peptidase) \/ N-methyltransferase [EC:3.4.23.43 2.1.1.-]"
			},
			{
				"name":"EcSMS35_3092 twitching motility family protein\tK02669 pilT; twitching motility protein PilT"
			}
			]
		},
		{
			"name":"Tight adherence (Tad) export apparatus"
		},
		{
			"name":"Toxin co-regulated pilus biosynthesis protein"
		},
		{
			"name":"MSHA pilus biogenesis protein"
		},
		{
			"name":"Type IVa pilus homolog protein",
			"children":[
			{
				"name":"EcSMS35_2973 ppdA; prepilin peptidase-dependent protein A\tK02679 ppdA; prepilin peptidase dependent protein A"
			},
			{
				"name":"EcSMS35_2972 ppdB; prepilin peptidase dependent protein B\tK02680 ppdB; prepilin peptidase dependent protein B"
			},
			{
				"name":"EcSMS35_2970 ppdC; prepilin peptidase-dependent protein C\tK02681 ppdC; prepilin peptidase dependent protein C"
			},
			{
				"name":"EcSMS35_0111 pilA; type 4 pilus subunit PilA\tK02682 ppdD; prepilin peptidase dependent protein D"
			},
			{
				"name":"EcSMS35_0110 hofB; GspE family protein HofB\tK02504 hofB; protein transport protein HofB"
			},
			{
				"name":"EcSMS35_0109 pilC; type IV pilus assembly protein PilC\tK02505 hofC; protein transport protein HofC"
			},
			{
				"name":"EcSMS35_3672 hofM; HofM protein\tK12288 hofM; pilus assembly protein HofM"
			},
			{
				"name":"EcSMS35_3671 PilN family protein\tK12289 hofN; pilus assembly protein HofN"
			},
			{
				"name":"EcSMS35_3669 conserved hypothetical protein\tK12290 hofO; pilus assembly protein HofO"
			},
			{
				"name":"EcSMS35_3668 conserved hypothetical protein\tK12291 hofP; pilus assembly protein HofP"
			},
			{
				"name":"EcSMS35_3667 protein transporter HofQ\tK02507 hofQ; protein transport protein HofQ"
			},
			{
				"name":"EcSMS35_3250 pppA; leader peptidase PppA\tK02654 pilD; leader peptidase (prepilin peptidase) \/ N-methyltransferase [EC:3.4.23.43 2.1.1.-]"
			},
			{
				"name":"EcSMS35_3092 twitching motility family protein\tK02669 pilT; twitching motility protein PilT"
			},
			{
				"name":"EcSMS35_3094 YGGT family protein\tK02221 yggT; YggT family protein"
			}
			]
		},
		{
			"name":"Archaeal flagellar protein"
		},
		{
			"name":"Competence-related DNA transformation transporter (DNA-T) core components",
			"children":[
			{
				"name":"EcSMS35_0485 competence protein ComEA\tK02237 comEA; competence protein ComEA"
			},
			{
				"name":"EcSMS35_2207 DNA internalization-related competence protein ComEC\/Rec2\tK02238 comEC; competence protein ComEC"
			}
			]
		},
		{
			"name":"Competence-related DNA transformation transporter (DNA-T) related proteins"
		}
		]
	},
	{
		"name":"Type III secretion system",
		"children":[
		{
			"name":"Type III secretion core apparatus"
		},
		{
			"name":"Type III secretion related proteins"
		},
		{
			"name":"Flagellar export apparatus",
			"children":[
			{
				"name":"EcSMS35_0241 lfhA; lateral flagellar export\/assembly protein LfhA\tK02400 flhA; flagellar biosynthesis protein FlhA"
			},
			{
				"name":"EcSMS35_1308 flhA; flagellar biosynthesis protein FlhA\tK02400 flhA; flagellar biosynthesis protein FlhA"
			},
			{
				"name":"EcSMS35_0242 lfhB; lateral flagellar export\/assembly protein LfhB\tK02401 flhB; flagellar biosynthesis protein FlhB"
			},
			{
				"name":"EcSMS35_1307 flhB; flagellar biosynthetic protein FlhB\tK02401 flhB; flagellar biosynthesis protein FlhB"
			},
			{
				"name":"EcSMS35_0250 lfiF; lateral flagellar M-ring protein LfiF\tK02409 fliF; flagellar M-ring protein FliF"
			},
			{
				"name":"EcSMS35_1246 fliF; flagellar M-ring protein FliF\tK02409 fliF; flagellar M-ring protein FliF"
			},
			{
				"name":"EcSMS35_0252 lfiH; lateral flagellar export\/assembly protein LfiH\tK02411 fliH; flagellar assembly protein FliH"
			},
			{
				"name":"EcSMS35_1244 fliH; flagellar assembly protein FliH\tK02411 fliH; flagellar assembly protein FliH"
			},
			{
				"name":"EcSMS35_0253 lfiI; lateral flagellar export\/assembly protein LfiI\tK02412 fliI; flagellum-specific ATP synthase [EC:7.4.2.8]"
			},
			{
				"name":"EcSMS35_1243 fliI; flagellar protein export ATPase FliI\tK02412 fliI; flagellum-specific ATP synthase [EC:7.4.2.8]"
			},
			{
				"name":"EcSMS35_0246 lfiN; lateral flagellar export\/assembly protein LfiN\tK02417 fliN; flagellar motor switch protein FliN"
			},
			{
				"name":"EcSMS35_1238 fliN; flagellar motor switch protein FliN\tK02417 fliN; flagellar motor switch protein FliN"
			},
			{
				"name":"EcSMS35_1237 fliO; flagellar protein FliO\tK02418 fliO; flagellar protein FliO\/FliZ"
			},
			{
				"name":"EcSMS35_0245 lfiP; lateral flagellar export\/assembly protein LfiP\tK02419 fliP; flagellar biosynthesis protein FliP"
			},
			{
				"name":"EcSMS35_1236 fliP; flagellar biosynthetic protein FliP\tK02419 fliP; flagellar biosynthesis protein FliP"
			},
			{
				"name":"EcSMS35_0244 lfiQ; lateral flagellar export\/assembly protein LfiQ\tK02420 fliQ; flagellar biosynthesis protein FliQ"
			},
			{
				"name":"EcSMS35_1235 fliQ; flagellar biosynthetic protein FliQ\tK02420 fliQ; flagellar biosynthesis protein FliQ"
			},
			{
				"name":"EcSMS35_0243 lfiR; lateral flagellar export\/assembly protein LfiR\tK02421 fliR; flagellar biosynthesis protein FliR"
			},
			{
				"name":"EcSMS35_1234 fliR; flagellar biosynthetic protein FliR\tK02421 fliR; flagellar biosynthesis protein FliR"
			}
			]
		}
		]
	},
	{
		"name":"Type IV secretion system",
		"children":[
		{
			"name":"Conjugal DNA-protein transfer (VirB\/D) protein"
		},
		{
			"name":"DNA uptake competence system protein"
		},
		{
			"name":"Conjugal transfer pilus assembly protein",
			"children":[
			{
				"name":"EcSMS35_A0014 traG; type IV secretion-like conjugative transfer system protein TraG\tK12056 traG; conjugal transfer mating pair stabilization protein TraG"
			},
			{
				"name":"EcSMS35_A0020 traF; type IV secretion-like conjugative transfer system pilus assembly protein TraF\tK12057 traF; conjugal transfer pilus assembly protein TraF"
			},
			{
				"name":"EcSMS35_A0022 traN; type IV secretion-like conjugative transfer system mating-pair stabilization protein TraN\tK12058 traN; conjugal transfer mating pair stabilization protein TraN"
			},
			{
				"name":"EcSMS35_A0023 trbC; type IV secretion-like conjugative transfer system pilus assembly protein TrbC\tK12059 trbC; conjugal transfer pilus assembly protein TrbC"
			},
			{
				"name":"EcSMS35_A0026 traU; type IV secretion-like conjugative transfer system protein TraU\tK12060 traU; conjugal transfer pilus assembly protein TraU"
			},
			{
				"name":"EcSMS35_A0027 traW; type IV secretion-like conjugative transfer system protein TraW\tK12061 traW; conjugal transfer pilus assembly protein TraW"
			},
			{
				"name":"EcSMS35_A0028 trbI; type IV secretion-like conjugative transfer system protein TrbI\tK28223 trbI; conjugal transfer pilus assembly protein TrbI"
			},
			{
				"name":"EcSMS35_A0029 traC; type IV secretion-like conjugative transfer system protein TraC\tK12063 traC; conjugal transfer ATP-binding protein TraC"
			},
			{
				"name":"EcSMS35_A0031 traV; type IV secretion-like conjugative transfer system protein TraV\tK12064 traV; conjugal transfer pilus assembly protein TraV"
			},
			{
				"name":"EcSMS35_A0035 traB; type IV secretion-like conjugative transfer system protein TraB\tK12065 traB; conjugal transfer pilus assembly protein TraB"
			},
			{
				"name":"EcSMS35_A0036 traK; type IV secretion-like conjugative transfer system secretin TraK\tK12066 traK; conjugal transfer pilus assembly protein TraK"
			},
			{
				"name":"EcSMS35_A0037 traE; type IV secretion-like conjugative transfer system protein TraE\tK12067 traE; conjugal transfer pilus assembly protein TraE"
			},
			{
				"name":"EcSMS35_A0038 traL; type IV secretion-like conjugative transfer system protein TraL\tK12068 traL; conjugal transfer pilus assembly protein TraL"
			},
			{
				"name":"EcSMS35_3026 dsbC; thiol:disulfide interchange protein DsbC\tK03981 dsbC; thiol:disulfide interchange protein DsbC [EC:5.3.4.1]"
			},
			{
				"name":"EcSMS35_A0015 traH; type IV secretion-like conjugative transfer system pilus assembly protein TraH\tK12072 traH; conjugative transfer pilus assembly protein TraH"
			}
			]
		},
		{
			"name":"Pertussis toxin exporter"
		},
		{
			"name":"Cag pathogenicity island (PAI) protein"
		},
		{
			"name":"Icm\/Dot secretion system protein"
		},
		{
			"name":"Trb secretion system protein"
		}
		]
	},
	{
		"name":"Type V secretion system",
		"children":[
		{
			"name":"Autotransporter-1 (AT-1) family",
			"children":[
			{
				"name":"EcSMS35_1662 pertactin family protein\tK12678 aidA-I; autotransporter family porin"
			},
			{
				"name":"EcSMS35_1980 porin, autotransporter (AT) family\tK12678 aidA-I; autotransporter family porin"
			},
			{
				"name":"EcSMS35_2510 outer membrane autotransporter domain protein\tK12678 aidA-I; autotransporter family porin"
			},
			{
				"name":"EcSMS35_2384 outer membrane autotransporter barrel domain protein\tK07279 yfaL; autotransporter family porin"
			},
			{
				"name":"EcSMS35_3921 outer membrane autotransporter barrel domain protein\tK12684 esp; serine protease autotransporter [EC:3.4.21.-]"
			},
			{
				"name":"EcSMS35_1767 putative autotransporter\tK12516 bigA; putative surface-exposed virulence protein"
			},
			{
				"name":"EcSMS35_2249 flu1; antigen 43\tK12687 flu; antigen 43"
			}
			]
		},
		{
			"name":"Autotransporter-2 (AT-2) family"
		},
		{
			"name":"Two-partner secretion (TPS) family"
		}
		]
	},
	{
		"name":"Type VI secretion system",
		"children":[
		{
			"name":"Imp\/Vas secretion system core components"
		},
		{
			"name":"Imp\/Vas secretion system related proteins"
		}
		]
	},
	{
		"name":"Type VII secretion system",
		"children":[
		{
			"name":"ESX secretion system protein"
		}
		]
	},
	{
		"name":"Chaperone-usher system",
		"children":[
		{
			"name":"Type 1 pilus assembly protein",
			"children":[
			{
				"name":"EcSMS35_0152 fimbrial protein\tK07345 fimA; major type 1 subunit fimbrin (pilin)"
			},
			{
				"name":"EcSMS35_1664 fimbrial protein\tK07345 fimA; major type 1 subunit fimbrin (pilin)"
			},
			{
				"name":"EcSMS35_2177 fimbrial protein\tK07345 fimA; major type 1 subunit fimbrin (pilin)"
			},
			{
				"name":"EcSMS35_2181 putative fimbrial protein\tK07345 fimA; major type 1 subunit fimbrin (pilin)"
			},
			{
				"name":"EcSMS35_4096 lpfA; long polar fimbrial operon protein LpfA\tK07345 fimA; major type 1 subunit fimbrin (pilin)"
			},
			{
				"name":"EcSMS35_4840 type-1 fimbrial protein homolog\tK07345 fimA; major type 1 subunit fimbrin (pilin)"
			},
			{
				"name":"EcSMS35_1665 periplasmic pilus chaperone family protein\tK07346 fimC; fimbrial chaperone protein"
			},
			{
				"name":"EcSMS35_2180 periplasmic pilus chaperone family protein\tK07346 fimC; fimbrial chaperone protein"
			},
			{
				"name":"EcSMS35_3925 putative fimbrial assembly chaperone FanE\tK07346 fimC; fimbrial chaperone protein"
			},
			{
				"name":"EcSMS35_4095 lpfB; long polar fimbrial operon protein LpfB\tK07346 fimC; fimbrial chaperone protein"
			},
			{
				"name":"EcSMS35_4843 fimC; chaperone protein FimC\tK07346 fimC; fimbrial chaperone protein"
			},
			{
				"name":"EcSMS35_0150 htrE; outer membrane usher protein HtrE\tK07347 fimD; outer membrane usher protein"
			},
			{
				"name":"EcSMS35_0934 fimbrial usher protein\tK07347 fimD; outer membrane usher protein"
			},
			{
				"name":"EcSMS35_1666 fimbrial usher family protein\tK07347 fimD; outer membrane usher protein"
			},
			{
				"name":"EcSMS35_2179 outer membrane usher protein fimD homolog\tK07347 fimD; outer membrane usher protein"
			},
			{
				"name":"EcSMS35_3926 putative fimbrial usher protein FanD\tK07347 fimD; outer membrane usher protein"
			},
			{
				"name":"EcSMS35_4094 lpfC; long polar fimbrial operon protein LpfC\tK07347 fimD; outer membrane usher protein"
			},
			{
				"name":"EcSMS35_4844 fimD1; outer membrane usher protein fimD\tK07347 fimD; outer membrane usher protein"
			},
			{
				"name":"EcSMS35_4845 fimF; fimbrial protein FimF\tK07348 fimF; minor fimbrial subunit"
			},
			{
				"name":"EcSMS35_1669 protein FimG homolog\tK07349 fimG; minor fimbrial subunit"
			},
			{
				"name":"EcSMS35_4846 fimG; protein fimG\tK07349 fimG; minor fimbrial subunit"
			},
			{
				"name":"EcSMS35_4847 fimH; protein FimH\tK07350 fimH; minor fimbrial subunit"
			}
			]
		},
		{
			"name":"P pilus assembly protein",
			"children":[
			{
				"name":"EcSMS35_2496 fimbrial usher protein\tK12518 papC; outer membrane usher protein PapC"
			},
			{
				"name":"EcSMS35_2495 fimbrial chaperone protein\tK12519 papD; chaperone protein PapD"
			}
			]
		},
		{
			"name":"Mat\/Ecp fimbriae assembly protein",
			"children":[
			{
				"name":"EcSMS35_0319 matB; fimbrillin MatB\tK21964 ecpA; Mat\/Ecp fimbriae major subunit"
			},
			{
				"name":"EcSMS35_0318 conserved hypothetical protein\tK21965 ecpB; Mat\/Ecp fimbriae periplasmic chaperone"
			},
			{
				"name":"EcSMS35_0317 conserved hypothetical protein\tK21966 ecpC; Mat\/Ecp fimbriae outer membrane usher protein"
			},
			{
				"name":"EcSMS35_0316 conserved hypothetical protein\tK21967 ecpD; Mat\/Ecp fimbriae adhesin"
			},
			{
				"name":"EcSMS35_0315 conserved hypothetical protein\tK21968 ecpE; Mat\/Ecp fimbriae periplasmic chaperone"
			}
			]
		}
		]
	},
	{
		"name":"Extracellular nucleation-precipitation pathway",
		"children":[
		{
			"name":"Curli assembly protein",
			"children":[
			{
				"name":"EcSMS35_2089 csgA; major curlin protein CsgA\tK04334 csgA; major curlin subunit"
			},
			{
				"name":"EcSMS35_2090 csgB; minor curlin protein CsgB\tK04335 csgB; minor curlin subunit"
			},
			{
				"name":"EcSMS35_2088 csgC; curli production protein CsgC\tK04336 csgC; curli production protein"
			},
			{
				"name":"EcSMS35_2094 csgE; curli production assembly\/transport subunit CsgE\tK04337 csgE; curli production assembly\/transport component CsgE"
			},
			{
				"name":"EcSMS35_2095 csgF; curli production assembly\/transport component CsgF\tK04338 csgF; curli production assembly\/transport component CsgF"
			},
			{
				"name":"EcSMS35_2096 csgG; curli production assembly\/transport subunit CsgG\tK06214 csgG; curli production assembly\/transport component CsgG"
			}
			]
		}
		]
	},
	{
		"name":"Sec (secretion) system",
		"children":[
		{
			"name":"Prokaryotic Sec-SRP core components",
			"children":[
			{
				"name":"EcSMS35_0103 secA; preprotein translocase, SecA subunit\tK03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]"
			},
			{
				"name":"EcSMS35_3946 secB; protein-export chaperone SecB\tK03071 secB; preprotein translocase subunit SecB"
			},
			{
				"name":"EcSMS35_0440 secD; protein-export membrane protein SecD\tK03072 secD; preprotein translocase subunit SecD"
			},
			{
				"name":"EcSMS35_4429 secE; preprotein translocase subunit secE\tK03073 secE; preprotein translocase subunit SecE"
			},
			{
				"name":"EcSMS35_0441 secF; protein-export membrane protein SecF\tK03074 secF; preprotein translocase subunit SecF"
			},
			{
				"name":"EcSMS35_3471 secG; preprotein translocase, SecG subunit\tK03075 secG; preprotein translocase subunit SecG"
			},
			{
				"name":"EcSMS35_0102 secM; secretion monitor protein\tK13301 secM; secretion monitor"
			},
			{
				"name":"EcSMS35_3595 secY; preprotein translocase, SecY subunit\tK03076 secY; preprotein translocase subunit SecY"
			},
			{
				"name":"EcSMS35_2762 ffh; signal recognition particle protein\tK03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]"
			},
			{
				"name":"EcSMS35_3747 ftsY; cell division protein FtsY\tK03110 ftsY; fused signal recognition particle receptor"
			},
			{
				"name":"EcSMS35_0439 yajC; preprotein translocase, YajC subunit\tK03210 yajC; preprotein translocase subunit YajC"
			},
			{
				"name":"EcSMS35_4072 inner membrane protein OxaA\tK03217 yidC; YidC\/Oxa1 family membrane protein insertase"
			}
			]
		},
		{
			"name":"Prokaryotic Sec-SRP related proteins"
		},
		{
			"name":"Eukaryotic Sec-SRP protein",
			"children":[
			{
				"name":"EcSMS35_2762 ffh; signal recognition particle protein\tK03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]"
			}
			]
		}
		]
	},
	{
		"name":"Twin-arginine translocation (Tat) system",
		"children":[
		{
			"name":"Twin-arginine translocation (Tat) pathway protein",
			"children":[
			{
				"name":"EcSMS35_4219 tatA; sec-independent protein translocase protein TatA\tK03116 tatA; sec-independent protein translocase protein TatA"
			},
			{
				"name":"EcSMS35_4220 tatB; twin arginine-targeting protein translocase TatB\tK03117 tatB; sec-independent protein translocase protein TatB"
			},
			{
				"name":"EcSMS35_4221 tatC; twin arginine-targeting protein translocase TatC\tK03118 tatC; sec-independent protein translocase protein TatC"
			},
			{
				"name":"EcSMS35_0647 twin arginine-targeting protein translocase, TatA\/E family\tK03425 tatE; sec-independent protein translocase protein TatE"
			}
			]
		}
		]
	}
	]
}