{
	"name":"ecv03000",
	"children":[
	{
		"name":"Eukaryotic type",
		"children":[
		{
			"name":"Basic leucine zipper (bZIP)",
			"children":[
			{
				"name":"AP-1(-like) components, Jun"
			},
			{
				"name":"AP-1(-like) components, Fos"
			},
			{
				"name":"AP-1(-like) components, Maf"
			},
			{
				"name":"AP-1(-like) components, NF-E2"
			},
			{
				"name":"AP-1(-like) components, Fungal regulators"
			},
			{
				"name":"AP-1(-like) components, CRE-BP\/ATF"
			},
			{
				"name":"CREB"
			},
			{
				"name":"C\/EBP-like factors"
			},
			{
				"name":"bZIP\/PAR"
			},
			{
				"name":"Plant bZIP factors"
			},
			{
				"name":"ZIP only"
			}
			]
		},
		{
			"name":"Basic helix-loop-helix (bHLH)",
			"children":[
			{
				"name":"Ubiquitous (class A) factors"
			},
			{
				"name":"Myogenic transcription factors"
			},
			{
				"name":"Achaete-Scute"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, Lymphoid factors"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, Mesodermal Twist-like factors"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, HEN"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, Mesp"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, Atonal"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, Pancreatic factors"
			},
			{
				"name":"Hairy, Hairy\/E(SPL)"
			},
			{
				"name":"Hairy, Fungal regulators"
			},
			{
				"name":"Factors with PAS domain"
			},
			{
				"name":"Yabby"
			},
			{
				"name":"INO"
			},
			{
				"name":"HLH domain only"
			}
			]
		},
		{
			"name":"Basic helix-loop-helix\/leucine zipper (bHLH-ZIP)",
			"children":[
			{
				"name":"Ubiquitous bHLH-ZIP factors"
			},
			{
				"name":"Cell cycle controlling factors, Myc"
			},
			{
				"name":"Cell cycle controlling factors, Mad\/Max"
			},
			{
				"name":"Other bHLH-ZIP factors"
			}
			]
		},
		{
			"name":"Other basic domains",
			"children":[
			{
				"name":"NF-1"
			},
			{
				"name":"RF-X"
			},
			{
				"name":"AP-2 (bHSH)"
			}
			]
		},
		{
			"name":"Zinc finger",
			"children":[
			{
				"name":"Cys4 thyroid hormone receptor-like"
			},
			{
				"name":"Cys4 hepatocyte nuclear factor 4-like"
			},
			{
				"name":"Cys4 estrogen receptor-like"
			},
			{
				"name":"Cys4 nerve growth factor IB-like"
			},
			{
				"name":"Cys4 Fushi tarazu-F1-like"
			},
			{
				"name":"Cys4 germ cell nuclear factor"
			},
			{
				"name":"Cys4 Knirps\/DAX1-like"
			},
			{
				"name":"Cys4 GATA-factors"
			},
			{
				"name":"Cys2His2 SP\/KLF family and related proteins"
			},
			{
				"name":"Cys2His2 GLI-like"
			},
			{
				"name":"Cys2His2 Snail"
			},
			{
				"name":"Cys2His2 BTB-ZF factors"
			},
			{
				"name":"Cys2His2 BED"
			},
			{
				"name":"Cys2His2 PRDM"
			},
			{
				"name":"Cys2His2 metabolic regulators in fungi"
			},
			{
				"name":"Cys2His2 others"
			},
			{
				"name":"Cys2HisCys zinc factors"
			},
			{
				"name":"Cys3His zinc factors"
			},
			{
				"name":"Cys2CysHis zinc factors"
			},
			{
				"name":"CXXC CpG-binding proteins",
				"children":[
				{
					"name":"APECO1_998 dcm; DNA cytosine methylase\tK00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]"
				},
				{
					"name":"APECO1_O1R127 cytosine methylase\tK00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]"
				}
				]
			},
			{
				"name":"Cys6 metabolic regulators in fungi"
			},
			{
				"name":"Other zinc fingers"
			}
			]
		},
		{
			"name":"Helix-turn-helix",
			"children":[
			{
				"name":"Homeo domain ANTP: HOXL"
			},
			{
				"name":"Homeo domain ANTP: NKL"
			},
			{
				"name":"Homeo domain Paired-related"
			},
			{
				"name":"Homeo domain LIM"
			},
			{
				"name":"Homeo domain POU"
			},
			{
				"name":"Homeo domain SINE"
			},
			{
				"name":"Homeo domain ZF"
			},
			{
				"name":"Homeo domain CUT"
			},
			{
				"name":"Homeo domain PROS"
			},
			{
				"name":"Homeo domain TALE"
			},
			{
				"name":"Homeo domain other"
			},
			{
				"name":"Fork head\/winged helix developmental regulators"
			},
			{
				"name":"Fork head\/winged helix tissue-specific regulators"
			},
			{
				"name":"Fork head\/winged helix cell cycle-controlling factors, E2F"
			},
			{
				"name":"Fork head\/winged helix cell cycle-controlling factors, DP"
			},
			{
				"name":"Fork head\/winged helix other regulators"
			},
			{
				"name":"Stork head\/winged helix factors"
			},
			{
				"name":"Heat shock factors"
			},
			{
				"name":"Tryptophan clusters Myb, Myb-factors"
			},
			{
				"name":"Tryptophan clusters Myb, Myb-like factors"
			},
			{
				"name":"Tryptophan clusters Ets-type"
			},
			{
				"name":"Tryptophan clusters interferon-regulating factors"
			},
			{
				"name":"TEA domain"
			},
			{
				"name":"ARID"
			}
			]
		},
		{
			"name":"beta-Scaffold factors with minor groove contacts",
			"children":[
			{
				"name":"RHR (Rel homology region) Rel\/Ankyrin"
			},
			{
				"name":"RHR (Rel homology region) Ankyrin only"
			},
			{
				"name":"RHR (Rel homology region) NF-AT"
			},
			{
				"name":"STAT"
			},
			{
				"name":"p53"
			},
			{
				"name":"MADS-box regulators of differentiation, MEF-2"
			},
			{
				"name":"MADS-box regulators of differentiation, Homeotic genes"
			},
			{
				"name":"MADS-box regulators of differentiation, Yeast regulators"
			},
			{
				"name":"MADS-box responders to external signals"
			},
			{
				"name":"SAND domain-containing proteins"
			},
			{
				"name":"TATA-binding proteins"
			},
			{
				"name":"HMG SOX"
			},
			{
				"name":"HMG TCF-1"
			},
			{
				"name":"HMG TOX"
			},
			{
				"name":"HMG2-related"
			},
			{
				"name":"UBF"
			},
			{
				"name":"Other HMG box factors"
			},
			{
				"name":"Heteromeric CCAAT factors"
			},
			{
				"name":"Grainyhead"
			},
			{
				"name":"Cold-shock domain factors, DbpA-like"
			},
			{
				"name":"Cold-shock domain factors, YB-1\/DbpB-like"
			},
			{
				"name":"Cold-shock domain factors, FRG Y2-like"
			},
			{
				"name":"Runt"
			},
			{
				"name":"MYRF"
			}
			]
		},
		{
			"name":"Other transcription factors",
			"children":[
			{
				"name":"HMGI(Y)"
			},
			{
				"name":"NUPR"
			},
			{
				"name":"Pocket domain Rb"
			},
			{
				"name":"Pocket domain CBP"
			},
			{
				"name":"T-box"
			},
			{
				"name":"DMRT"
			},
			{
				"name":"LRRFIP"
			},
			{
				"name":"TCP"
			},
			{
				"name":"AP2\/ERF"
			},
			{
				"name":"WRKY"
			},
			{
				"name":"LOB"
			},
			{
				"name":"GRAS"
			},
			{
				"name":"NAC"
			},
			{
				"name":"Copper-fist proteins fungal regulators"
			},
			{
				"name":"Others"
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic type",
		"children":[
		{
			"name":"Helix-turn-helix",
			"children":[
			{
				"name":"AraC family",
				"children":[
				{
					"name":"APECO1_1920 araC; transcriptional regulator AraC\tK02099 araC; AraC family transcriptional regulator, arabinose operon regulatory protein"
				},
				{
					"name":"APECO1_2562 rhaR; DNA-binding transcriptional activator, L-rhamnose-binding\tK02854 rhaR; AraC family transcriptional regulator, L-rhamnose operon transcriptional activator RhaR"
				},
				{
					"name":"APECO1_2563 rhaS; DNA-binding transcriptional activator, L-rhamnose-binding protein RhaS\tK02855 rhaS; AraC family transcriptional regulator, L-rhamnose operon regulatory protein RhaS"
				},
				{
					"name":"APECO1_804 celD; CelD transcriptional regulator\tK03490 chbR; AraC family transcriptional regulator, dual regulator of chb operon"
				},
				{
					"name":"APECO1_2335 adiY; putative regulatory protein AdiY\tK03755 adiY; AraC family transcriptional regulator, transcriptional activator of adiA"
				},
				{
					"name":"APECO1_4111 yfeG; ethanolamine operon regulatory protein\tK04033 eutR; AraC family transcriptional regulator, ethanolamine operon transcriptional activator"
				},
				{
					"name":"APECO1_1057 putative AraC type regulator\tK05372 ybtA; AraC family transcriptional regulator"
				},
				{
					"name":"APECO1_649 marA; Multiple antibiotic resistance protein MarA\tK13632 marA; AraC family transcriptional regulator, mar-sox-rob regulon activator"
				},
				{
					"name":"APECO1_1983 rob; right origin-binding protein\tK05804 rob; AraC family transcriptional regulator, mar-sox-rob regulon activator"
				},
				{
					"name":"APECO1_1689 ykgD; putative DNA-binding transcriptional regulator\tK21746 rclR; AraC family transcriptional regulator, reactive chlorine species (RCS)-specific activator of rcl operon"
				},
				{
					"name":"APECO1_2933 yhiW; DNA-binding transcriptional activator YhiW\tK21906 gadW; AraC family transcriptional regulator, glutamate-dependent acid resistance regulator"
				},
				{
					"name":"APECO1_2932 gadX; DNA-binding transcriptional dual regulator GadX\tK21905 gadX; AraC family transcriptional regulator, glutamate-dependent acid resistance regulator"
				},
				{
					"name":"APECO1_2333 melR; MelR regulator of melibiose operon\tK23237 melR; AraC family transcriptional regulator, melibiose operon regulatory protein"
				},
				{
					"name":"APECO1_856 yeaM; putative transcriptional regulator\tK25495 nimR; AraC family transcriptional regulator, regulator of nimT"
				},
				{
					"name":"APECO1_4346 ada; Ada transcriptional dual regulator \/ O-6-methylguanine-DNA methyltransferase\tK10778 ada; AraC family transcriptional regulator, regulatory protein of adaptative response \/ methylated-DNA-[protein]-cysteine methyltransferase [EC:2.1.1.63]"
				}
				]
			},
			{
				"name":"LysR family",
				"children":[
				{
					"name":"APECO1_3723 gcvA; positive regulator of gcv operon\tK03566 gcvA; LysR family transcriptional regulator, glycine cleavage system transcriptional activator"
				},
				{
					"name":"APECO1_2698 ilvY; transcriptional activator protein IlvY\tK02521 ilvY; LysR family transcriptional regulator, positive regulator for ilvC"
				},
				{
					"name":"APECO1_2648 metR; DNA-binding transcriptional activator, homocysteine-binding\tK03576 metR; LysR family transcriptional regulator, regulator for metE and metH"
				},
				{
					"name":"APECO1_1959 nhaR; DNA-binding transcriptional activator\tK03717 nhaR; LysR family transcriptional regulator, transcriptional activator of nhaA"
				},
				{
					"name":"APECO1_2504 oxyR; hydrogen peroxide-inducible genes activator\tK04761 oxyR; LysR family transcriptional regulator, hydrogen peroxide-inducible genes activator"
				},
				{
					"name":"APECO1_3614 iciA; chromosome replication initiation inhibitor protein\tK05596 argP; LysR family transcriptional regulator, arginine and lysine transport system\/DNA replication regulator"
				},
				{
					"name":"APECO1_1908 leuO; leucine transcriptional activator\tK05798 leuO; LysR family transcriptional regulator, transcriptional activator for leuABCD operon"
				},
				{
					"name":"APECO1_3306 tdcA; transcriptional activator of tdc operon\tK07592 tdcA; LysR family transcriptional regulator, tdc operon transcriptional activator"
				},
				{
					"name":"APECO1_1510 ybbS; putative transcriptional regulator YbbS\tK10972 allS; LysR family transcriptional regulator, transcriptional activator of the allD operon"
				},
				{
					"name":"APECO1_435 conserved hypothetical protein\tK13634 cysB; LysR family transcriptional regulator, cys regulon transcriptional activator"
				},
				{
					"name":"APECO1_6021 cbl; DNA-binding transcriptional activator of cysteine biosynthesis\tK13635 cbl; LysR family transcriptional regulator, cys regulon transcriptional activator"
				},
				{
					"name":"APECO1_4172 dsdC; D-serine deaminase activator\tK13636 dsdC; LysR family transcriptional regulator, D-serine deaminase activator"
				},
				{
					"name":"APECO1_6022 nac; DNA-binding transcriptional dual regulator of nitrogen assimilation\tK19338 nac; LysR family transcriptional regulator, nitrogen assimilation regulatory protein"
				},
				{
					"name":"APECO1_2091 yjiE; putative DNA-binding transcriptional regulator\tK21645 hypT; LysR family transcriptional regulator, hypochlorite-specific transcription factor HypT"
				},
				{
					"name":"APECO1_3201 aaeR; putative DNA-binding transcriptional regulator, efflux system\tK21698 aaeR; LysR family transcriptional regulator, transcriptional activator for aaeXAB operon"
				},
				{
					"name":"APECO1_3354 putative transcriptional regulator YgiP\tK21742 ttdR; LysR family transcriptional regulator, transcriptional activator for ttdABT operon"
				},
				{
					"name":"APECO1_2706 hdfR; transcriptional regulator HdfR\tK23773 hdfR; LysR family transcriptional regulator, flagellar master operon regulator"
				},
				{
					"name":"APECO1_482 ycjZ; hypothetical transcriptional regulator YcjZ\tK24082 pgrR; LysR family transcriptional regulator, regulator of peptidoglycan recycling"
				}
				]
			},
			{
				"name":"DeoR family",
				"children":[
				{
					"name":"APECO1_1253 deoR; DeoR transcriptional repressor\tK11534 deoR; DeoR family transcriptional regulator, deoxyribose operon repressor"
				},
				{
					"name":"APECO1_3044 glpR; glycerol-3-phosphate regulon repressor GlpR\tK02444 glpR; DeoR family transcriptional regulator, glycerol-3-phosphate regulon repressor"
				},
				{
					"name":"APECO1_4455 gatR; galactitol utilization operon repressor\tK02436 gatR; DeoR family transcriptional regulator, galactitol utilization operon repressor"
				},
				{
					"name":"APECO1_3298 agaR; DNA-binding transcriptional dual regulator\tK02081 agaR; DeoR family transcriptional regulator, aga operon transcriptional repressor"
				},
				{
					"name":"APECO1_3726 fucR; L-fucose operon activator\tK02430 fucR; DeoR family transcriptional regulator, L-fucose operon activator"
				},
				{
					"name":"APECO1_3819 srlR; DNA-binding transcriptional repressor\tK02468 srlR; DeoR family transcriptional regulator, glucitol operon repressor"
				},
				{
					"name":"APECO1_2201 yjfQ; putative DEOR-type transcriptional regulator\tK03477 ulaR; DeoR family transcriptional regulator, ulaG and ulaABCDEF operon transcriptional repressor"
				},
				{
					"name":"APECO1_2590 putative bacterial regulatory protein\tK27243 csqR; DeoR family transcriptional regulator, sulfoquinovose operon repressor"
				}
				]
			},
			{
				"name":"LacI family",
				"children":[
				{
					"name":"APECO1_1648 lacI; lac operon repressor\tK27069 lacI; LacI family transcriptional regulator, lactose operon repressor"
				},
				{
					"name":"APECO1_2416 putative transcriptional regulator, LacI family\tK02529 galR; LacI family transcriptional regulator, galactose operon repressor"
				},
				{
					"name":"APECO1_2710 rbsR; DNA-binding transcriptional repressor of ribose metabolism\tK02529 galR; LacI family transcriptional regulator, galactose operon repressor"
				},
				{
					"name":"APECO1_2881 xylR; DNA-binding transcriptional activator, xylose-binding\tK02529 galR; LacI family transcriptional regulator, galactose operon repressor"
				},
				{
					"name":"APECO1_3669 galR; galactose operon repressor\tK02529 galR; LacI family transcriptional regulator, galactose operon repressor"
				},
				{
					"name":"APECO1_4400 galS; Mgl repressor and galactose ultrainduction factor\tK02529 galR; LacI family transcriptional regulator, galactose operon repressor"
				},
				{
					"name":"APECO1_2536 cytR; transcriptional repressor CytR\tK05499 cytR; LacI family transcriptional regulator, repressor for deo operon, udp, cdd, tsx, nupC, and nupG"
				},
				{
					"name":"APECO1_1905 fruR; transcriptional repressor of fru operon\tK03435 fruR1; LacI family transcriptional regulator, fructose operon transcriptional repressor"
				},
				{
					"name":"APECO1_2151 treR; trehalose operon repressor\tK03485 treR; LacI family transcriptional regulator, trehalose operon repressor"
				},
				{
					"name":"APECO1_3812 ascG; ascBF operon repressor\tK03487 ascG; LacI family transcriptional regulator, asc operon repressor"
				},
				{
					"name":"APECO1_738 purR; purine nucleotide synthesis repressor\tK03604 purR; LacI family transcriptional regulator, purine nucleotide synthesis repressor"
				},
				{
					"name":"APECO1_3020 gntR; DNA-binding transcriptional repressor\tK06145 gntR; LacI family transcriptional regulator, gluconate utilization system Gnt-I transcriptional repressor"
				},
				{
					"name":"APECO1_2130 idnR; L-idonate regulatory protein\tK06146 idnR; LacI family transcriptional regulator, gluconate utilization system Gnt-II transcriptional activator"
				},
				{
					"name":"APECO1_3341 ebgR; Ebg operon repressor\tK12113 ebgR; LacI family transcriptional regulator, ebg operon repressor"
				},
				{
					"name":"APECO1_703 malI; maltose regulon regulatory protein MalI\tK16136 malI; LacI family transcriptional regulator, maltose regulon regulatory protein"
				}
				]
			},
			{
				"name":"GntR family",
				"children":[
				{
					"name":"APECO1_655 putative transcriptional regulator\tK03482 yidP; GntR family transcriptional regulator, glv operon transcriptional regulator"
				},
				{
					"name":"APECO1_2348 phnF; PhnF, putative DNA-binding transcriptional regulator of phosphonate uptake and biodegradation\tK02043 phnF; GntR family transcriptional regulator, phosphonate transport system regulatory protein"
				},
				{
					"name":"APECO1_299 fadR; negative regulator for fad regulon, and positive activator of fabA\tK03603 fadR; GntR family transcriptional regulator, negative regulator for fad regulon and positive regulator of fabA"
				},
				{
					"name":"APECO1_1872 pdhR; transcriptional regulator for pyruvate dehydrogenase complex\tK05799 pdhR; GntR family transcriptional regulator, transcriptional repressor for pyruvate dehydrogenase complex"
				},
				{
					"name":"APECO1_3447 glcC; Glc operon transcriptional activator\tK11474 glcC; GntR family transcriptional regulator, glc operon transcriptional activator"
				},
				{
					"name":"APECO1_2107 uxuR; UxuR, uxu operon transcriptional regulator\tK13637 uxuR; GntR family transcriptional regulator, uxu operon transcriptional repressor"
				},
				{
					"name":"APECO1_3409 putative regulator\tK13637 uxuR; GntR family transcriptional regulator, uxu operon transcriptional repressor"
				},
				{
					"name":"APECO1_3325 exuR; negative regulator of Exu regulon, ExuT, UxaAC, and UxuB\tK19775 exuR; GntR family transcriptional regulator, hexuronate regulon transcriptional repressor"
				},
				{
					"name":"APECO1_2851 lldR; DNA-binding transcriptional repressor\tK14348 lldR; GntR family transcriptional regulator, L-lactate dehydrogenase operon regulator"
				},
				{
					"name":"APECO1_2762 dgoR; putative galactonate operon transcriptional repressor DgoR\tK19776 dgoR; GntR family transcriptional regulator, galactonate operon transcriptional repressor"
				},
				{
					"name":"APECO1_3217 nanR; transcriptional regulator NanR\tK22104 nanR; GntR family transcriptional regulator, sialic acid-inducible nan operon repressor"
				},
				{
					"name":"APECO1_3849 putative regulatory protein, GntR family\tK00375 K00375; GntR family transcriptional regulator \/ MocR family aminotransferase"
				},
				{
					"name":"APECO1_38572 ygaE; putative transcriptional regulator YgaE\tK15735 csiR; GntR family transcriptional regulator, carbon starvation induced regulator"
				},
				{
					"name":"APECO1_660 conserved hypothetical protein\tK22293 rspR; GntR family transcriptional regulator, rspAB operon transcriptional repressor"
				},
				{
					"name":"APECO1_2067 yjjM; putative DNA-binding transcriptional regulator\tK23015 lgoR; GntR family transcriptional regulator, transcriptional activator for L-galactonate catabolism"
				}
				]
			},
			{
				"name":"TetR\/AcrR family",
				"children":[
				{
					"name":"APECO1_O1R84 tetR; TetR\tK18476 tetR; TetR\/AcrR family transcriptional regulator, tetracycline repressor protein"
				},
				{
					"name":"APECO1_1677 betI; regulatory protein BetI\tK02167 betI; TetR\/AcrR family transcriptional regulator, transcriptional repressor of bet genes"
				},
				{
					"name":"APECO1_1550 acrR; acrAB operon repressor\tK03577 acrR; TetR\/AcrR family transcriptional regulator, acrAB operon repressor"
				},
				{
					"name":"APECO1_2820 ttk; putative transcriptional regulator\tK05501 slmA; TetR\/AcrR family transcriptional regulator"
				},
				{
					"name":"APECO1_104 ycdC; transcriptional regulator YcdC\tK09017 rutR; TetR\/AcrR family transcriptional regulator"
				},
				{
					"name":"APECO1_731 ydhM; putative DNA-binding transcriptional regulator\tK16137 nemR; TetR\/AcrR family transcriptional regulator, transcriptional repressor for nem operon"
				},
				{
					"name":"APECO1_701 uidR; repressor for uid operon\tK16138 uidR; TetR\/AcrR family transcriptional regulator, repressor for uid operon"
				},
				{
					"name":"APECO1_3175 envR; putative acrEF\/envCD operon repressor\tK18140 envR; TetR\/AcrR family transcriptional regulator, acrEF\/envCD operon repressor"
				},
				{
					"name":"APECO1_192 ycfQ; putative transcriptional regulator\tK22041 comR; TetR\/AcrR family transcriptional regulator, copper-responsive repressor"
				},
				{
					"name":"APECO1_2500 yijC; putative TetR-family transcriptional regulatory protein YijC\tK22105 fabR; TetR\/AcrR family transcriptional regulator, fatty acid biosynthesis regulator"
				},
				{
					"name":"APECO1_1294 ybiH; putative transcriptional regulator\tK23777 cecR; TetR\/AcrR family transcriptional regulator, regulator of cefoperazone and chloramphenicol sensitivity"
				},
				{
					"name":"APECO1_1247 ybjK; putative DEOR-type transcriptional regulator\tK23778 rcdA; TetR\/AcrR family transcriptional regulator, regulator of biofilm formation and stress response"
				}
				]
			},
			{
				"name":"Lrp\/AsnC family",
				"children":[
				{
					"name":"APECO1_2720 asnC; DNA-binding transcriptional dual regulator\tK03718 asnC; Lrp\/AsnC family transcriptional regulator, regulator for asnA, asnC and gidA"
				},
				{
					"name":"APECO1_1200 lrp; Leucine-responsive Regulatory protein\tK03719 lrp; Lrp\/AsnC family transcriptional regulator, leucine-responsive regulatory protein"
				},
				{
					"name":"APECO1_1564 ybaO; putative transcriptional regulator YbaO\tK05800 decR; Lrp\/AsnC family transcriptional regulator, cysteine-sensing transcriptional activator"
				}
				]
			},
			{
				"name":"LuxR family",
				"children":[
				{
					"name":"APECO1_957 sdiA; DNA-binding transcriptional activator\tK07782 sdiA; LuxR family transcriptional regulator, quorum-sensing system regulator SdiA"
				},
				{
					"name":"APECO1_1703 ykgK; conserved hypothetical protein\tK21963 ecpR; LuxR family transcriptional regulator, Mat\/Ecp fimbriae transcriptional regulator"
				},
				{
					"name":"APECO1_990 rcsA; positive regulator for ctr capsule biosynthesis, positive transcription factor\tK07781 rcsA; LuxR family transcriptional regulator, capsular biosynthesis positive transcription factor"
				},
				{
					"name":"APECO1_125 csgD; probable csgAB operon transcriptional regulatory protein\tK04333 csgD; LuxR family transcriptional regulator, csgAB operon transcriptional regulatory protein"
				},
				{
					"name":"APECO1_2950 yhiF; predicted DNA-binding ranscriptional regulator\tK21901 dctR; LuxR family transcriptional regulator, dicarboxylate transport regulator"
				},
				{
					"name":"APECO1_2058 bglJ; BglJ 2-component transcriptional regulator\tK22650 bglJ; LuxR family transcriptional regulator, regulator of transport and utilization of aryl beta-glucosides"
				},
				{
					"name":"APECO1_3048 malT; MalT-maltotriose-ATP transcriptional activator MalT\tK03556 malT; LuxR family transcriptional regulator, maltose regulon positive regulatory protein"
				},
				{
					"name":"APECO1_2937 gadE; putative DNA-binding transcriptional activator\tK21907 gadE; LuxR family transcriptional regulator, glutamate-dependent acid resistance regulator"
				}
				]
			},
			{
				"name":"MarR family",
				"children":[
				{
					"name":"APECO1_648 marR; multiple antibiotic resistance protein MarR\tK03712 marR; MarR family transcriptional regulator, multiple antibiotic resistance protein MarR"
				},
				{
					"name":"APECO1_725 slyA; transcriptional regulator SlyA\tK06075 slyA; MarR family transcriptional regulator, transcriptional regulator for hemolysin"
				},
				{
					"name":"APECO1_1713 conserved hypothetical protein\tK15974 emrR; MarR family transcriptional regulator, negative regulator of the multidrug operon emrRAB"
				},
				{
					"name":"APECO1_2260 papX; putative regulator PapX protein\tK15974 emrR; MarR family transcriptional regulator, negative regulator of the multidrug operon emrRAB"
				},
				{
					"name":"APECO1_3838 mprA; DNA-binding transcriptional repressor of microcin B17 synthesis\tK15974 emrR; MarR family transcriptional regulator, negative regulator of the multidrug operon emrRAB"
				}
				]
			},
			{
				"name":"MerR family",
				"children":[
				{
					"name":"APECO1_1525 ybbI; putative transcriptional regulator\tK19591 cueR; MerR family transcriptional regulator, copper efflux regulator"
				},
				{
					"name":"APECO1_3155 zntR; zinc-responsive transcriptional regulator\tK13638 zntR; MerR family transcriptional regulator, Zn(II)-responsive regulator of zntA"
				},
				{
					"name":"APECO1_2394 soxR; redox-sensitive transcriptional activator SoxR\tK13639 soxR; MerR family transcriptional regulator, redox-sensitive transcriptional activator SoxR"
				},
				{
					"name":"APECO1_4422 yehV; MerR-like regulator A\tK21089 mlrA; MerR family transcriptional regulator, activator of the csg genes"
				},
				{
					"name":"APECO1_277 ycgE; putative transcriptional regulator\tK21972 bluR; MerR family transcriptional regulator, repressor of blue light- and temperature-responsive genes"
				}
				]
			},
			{
				"name":"Fur family",
				"children":[
				{
					"name":"APECO1_1381 fur; ferric uptake regulator\tK03711 fur; Fur family transcriptional regulator, ferric uptake regulator"
				},
				{
					"name":"APECO1_2424 yjbK; putative zinc uptake regulation protein\tK09823 zur; Fur family transcriptional regulator, zinc uptake regulator"
				}
				]
			},
			{
				"name":"IclR family",
				"children":[
				{
					"name":"APECO1_2459 iclR; aceBAK operon repressor\tK13641 iclR; IclR family transcriptional regulator, acetate operon repressor"
				},
				{
					"name":"APECO1_1508 ybbU; putative regulator of allantoin regulon YbbU\tK10973 allR; IclR family transcriptional regulator, negative regulator of allantoin and glyoxylate utilization operons"
				},
				{
					"name":"APECO1_882 kdgR; transcriptional regulator\tK19333 kdgR; IclR family transcriptional regulator, KDG regulon repressor"
				},
				{
					"name":"APECO1_2876 yiaJ; predicted DNA-binding transcriptional repressor\tK21602 plaR; IclR family transcriptional regulator, regulator of plant utilization"
				}
				]
			},
			{
				"name":"CRP\/FNR family",
				"children":[
				{
					"name":"APECO1_3098 crp; DNA-binding transcriptional dual regulator\tK10914 crp; CRP\/FNR family transcriptional regulator, cyclic AMP receptor protein"
				},
				{
					"name":"APECO1_487 fnr; fumarate and nitrate reduction regulatory protein\tK01420 fnr; CRP\/FNR family transcriptional regulator, anaerobic regulatory protein"
				},
				{
					"name":"APECO1_4391 yeiL; ribonucleoside hydrolase 2\tK16326 yeiL; CRP\/FNR family transcriptional regulator, putaive post-exponential-phase nitrogen-starvation regulator"
				}
				]
			},
			{
				"name":"Rrf2 family",
				"children":[
				{
					"name":"APECO1_3994 iscR; DNA-binding transcriptional repressor\tK13643 iscR; Rrf2 family transcriptional regulator, iron-sulfur cluster assembly transcription factor"
				},
				{
					"name":"APECO1_2214 yjeB; conserved hypothetical protein\tK13771 nsrR; Rrf2 family transcriptional regulator, nitric oxide-sensitive transcriptional repressor"
				}
				]
			},
			{
				"name":"ArsR family"
			},
			{
				"name":"XRE family",
				"children":[
				{
					"name":"APECO1_579 ydcN; conserved hypothetical protein\tK23779 sutR; XRE family transcriptional regulator, regulator of sulfur utilization"
				}
				]
			},
			{
				"name":"PadR family"
			},
			{
				"name":"Other families",
				"children":[
				{
					"name":"APECO1_1275 mntR; DNA-binding transcriptional regulator of mntH\tK11924 mntR; DtxR family transcriptional regulator, manganese transport regulator"
				},
				{
					"name":"APECO1_2361 rpiR; putative transcriptional regulator RpiR\tK23238 rpiR; RpiR family transcriptional regulator, repressor of rpiB and als operon"
				},
				{
					"name":"APECO1_903 yebK; hex regulon repressor\tK19337 hexR; RpiR family transcriptional regulator, carbohydrate utilization regulator"
				},
				{
					"name":"APECO1_2494 birA; BirA bifunctional protein\tK03524 birA; BirA family transcriptional regulator, biotin operon repressor \/ biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]"
				},
				{
					"name":"APECO1_3177 fis; DNA-binding protein\tK03557 fis; Fis family transcriptional regulator, factor for inversion stimulation protein"
				},
				{
					"name":"APECO1_1986 trpR; trp operon repressor\tK03720 trpR; TrpR family transcriptional regulator, trp operon repressor"
				},
				{
					"name":"APECO1_1658 prpR; DNA-binding transcriptional activator\tK02688 prpR; transcriptional regulator, propionate catabolism operon regulatory protein"
				},
				{
					"name":"APECO1_3246 nlp; sugar fermentation stimulation protein B\tK07724 ner; Ner family transcriptional regulator"
				},
				{
					"name":"APECO1_1913 sgrR; DNA-binding transcriptional regulator\tK11925 sgrR; SgrR family transcriptional regulator"
				},
				{
					"name":"APECO1_1991 nadR; transcriptional regulator NadR\tK06211 nadR; HTH-type transcriptional regulator, transcriptional repressor of NAD biosynthesis genes [EC:2.7.7.1 2.7.1.22]"
				},
				{
					"name":"APECO1_2412 NadR transcriptional repressor \/ NMN adenylyltransferase\tK06211 nadR; HTH-type transcriptional regulator, transcriptional repressor of NAD biosynthesis genes [EC:2.7.7.1 2.7.1.22]"
				},
				{
					"name":"APECO1_638 hipB; HipB transcriptional activator\tK15773 hipB; HTH-type transcriptional regulator \/ antitoxin HipB"
				},
				{
					"name":"APECO1_O1R105 putative transcriptional regulator\tK15773 hipB; HTH-type transcriptional regulator \/ antitoxin HipB"
				},
				{
					"name":"APECO1_O1R78 conserved hypothetical protein\tK15773 hipB; HTH-type transcriptional regulator \/ antitoxin HipB"
				},
				{
					"name":"APECO1_3809 conserved hypothetical protein\tK18831 higA; HTH-type transcriptional regulator \/ antitoxin HigA"
				},
				{
					"name":"APECO1_3817 ygaA; putative sigma-54-dependent transcriptional regulator YgaA\tK12266 norR; anaerobic nitric oxide reductase transcription regulator"
				},
				{
					"name":"APECO1_3794 fhlA; formate hydrogenlyase transcriptional activator\tK15836 fhlA; formate hydrogenlyase transcriptional activator"
				},
				{
					"name":"APECO1_1823 cdaR; carbohydrate diacid regulator\tK02647 cdaR; carbohydrate diacid regulator"
				},
				{
					"name":"APECO1_1327 modE; transcriptional regulator modE\tK02019 modE; molybdate transport system regulatory protein"
				},
				{
					"name":"APECO1_3793 putative molybdenum-pterin-binding-protein\tK02019 modE; molybdate transport system regulatory protein"
				},
				{
					"name":"APECO1_1989 putative regulatory protein\tK07726 K07726; putative transcriptional regulator"
				},
				{
					"name":"APECO1_2576 conserved hypothetical protein\tK07726 K07726; putative transcriptional regulator"
				},
				{
					"name":"APECO1_2893 yiaG; putative transcriptional regulator\tK07726 K07726; putative transcriptional regulator"
				},
				{
					"name":"APECO1_231 conserved hypothetical protein\tK07729 K07729; putative transcriptional regulator"
				}
				]
			}
			]
		},
		{
			"name":"Ribbon-helix-helix",
			"children":[
			{
				"name":"CopG family",
				"children":[
				{
					"name":"APECO1_2973 nikR; nickel responsive regulator NikR\tK07722 nikR; CopG family transcriptional regulator, nickel-responsive regulator"
				}
				]
			},
			{
				"name":"Other families",
				"children":[
				{
					"name":"APECO1_2533 metJ; transcriptional repressor for methionine biosynthesis (MetJ family)\tK03764 metJ; MetJ family transcriptional regulator, methionine regulon repressor"
				},
				{
					"name":"APECO1_105 putA; delta-1-pyrroline-5-carboxylate dehydrogenase\tK13821 putA; RHH-type transcriptional regulator, proline utilization regulon repressor \/ proline dehydrogenase \/ delta 1-pyrroline-5-carboxylate dehydrogenase [EC:1.5.5.2 1.2.1.88]"
				}
				]
			}
			]
		},
		{
			"name":"Other transcription factors",
			"children":[
			{
				"name":"BglG family",
				"children":[
				{
					"name":"APECO1_2738 bglG; transcriptional antiterminator of the bgl operon\tK03488 licT; beta-glucoside operon transcriptional antiterminator"
				},
				{
					"name":"APECO1_3689 antiterminator\tK03488 licT; beta-glucoside operon transcriptional antiterminator"
				}
				]
			},
			{
				"name":"Others",
				"children":[
				{
					"name":"APECO1_1644 frmR; regulator protein that represses frmRAB operon\tK23239 frmR; FrmR\/RcnR family transcriptional regulator, repressor of frmRAB operon"
				},
				{
					"name":"APECO1_1576 bolA; regulator of penicillin binding proteins and beta lactamase transcription\tK05527 bolA; BolA family transcriptional regulator, general stress-responsive regulator"
				},
				{
					"name":"APECO1_O1CoBM16 conserved hypothetical protein\tK03497 parB; ParB family transcriptional regulator, chromosome partitioning protein"
				},
				{
					"name":"APECO1_O1CoBM4 sopB; SopB\tK03497 parB; ParB family transcriptional regulator, chromosome partitioning protein"
				},
				{
					"name":"APECO1_O1R13 parB; ParB\tK03497 parB; ParB family transcriptional regulator, chromosome partitioning protein"
				},
				{
					"name":"APECO1_2615 rfaH; transcriptional activator RfaH\tK05785 rfaH; transcriptional antiterminator RfaH"
				},
				{
					"name":"APECO1_2146 putative arganine repressor\tK03402 argR; transcriptional regulator of arginine metabolism"
				},
				{
					"name":"APECO1_3207 argR; repressor of arg regulon ArgR\tK03402 argR; transcriptional regulator of arginine metabolism"
				},
				{
					"name":"APECO1_1396 nagC; transcriptional repressor of nag\tK02565 nagC; N-acetylglucosamine repressor"
				},
				{
					"name":"APECO1_677 mlc; Mlc protein\tK15545 mlc; transcriptional regulator of PTS gene"
				},
				{
					"name":"APECO1_2856 mtlR; mtl operon repressor MtlR\tK02562 mtlR; mannitol operon repressor"
				},
				{
					"name":"APECO1_476 tyrR; transcriptional regulatory protein TyrR\tK03721 tyrR; transcriptional regulator of aroF, aroG, tyrA and aromatic amino acid transport"
				},
				{
					"name":"APECO1_2320 cadC; transcriptional activator CadC\tK03765 cadC; transcriptional activator of cad operon"
				},
				{
					"name":"APECO1_4078 gcvR; DNA-binding transcriptional repressor, regulatory protein accessory to GcvA\tK03567 gcvR; glycine cleavage system transcriptional repressor"
				},
				{
					"name":"APECO1_458 pspF; psp operon transcriptional activator\tK03974 pspF; psp operon transcriptional activator"
				},
				{
					"name":"APECO1_460 pspC; phage shock protein C\tK03973 pspC; phage shock protein C"
				},
				{
					"name":"APECO1_2094 ibeR; putative regulatory protein IbeR\tK05880 dhaR; transcriptional activator for dhaKLM operon"
				},
				{
					"name":"APECO1_318 glycerol metabolism operon regulatory protein\tK05880 dhaR; transcriptional activator for dhaKLM operon"
				},
				{
					"name":"APECO1_1441 rnk; regulator of nucleoside diphosphate kinase\tK06140 rnk; regulator of nucleoside diphosphate kinase"
				},
				{
					"name":"APECO1_1086 putative transcriptional regulator\tK07733 alpA; prophage regulatory protein"
				},
				{
					"name":"APECO1_4024 putative phage regulatory protein\tK07733 alpA; prophage regulatory protein"
				},
				{
					"name":"APECO1_3573 yqgE; conserved hypothetical protein\tK07735 algH; putative transcriptional regulator"
				},
				{
					"name":"APECO1_1947 caiF; transcriptional regulator of cai operon\tK08277 caiF; transcriptional activator CaiF"
				},
				{
					"name":"APECO1_1840 dksA; DnaK suppressor protein\tK06204 dksA; RNA polymerase-binding transcription factor"
				},
				{
					"name":"APECO1_1597 nrdR; NrdR repressor protein\tK07738 nrdR; transcriptional repressor NrdR"
				},
				{
					"name":"APECO1_1729 crl; crl transcriptional regulator\tK11926 crl; sigma factor-binding protein Crl"
				},
				{
					"name":"APECO1_3045 rtcR; transcriptional regulatory protein RtcR\tK14414 rtcR; transcriptional regulatory protein RtcR"
				},
				{
					"name":"APECO1_377 conserved hypothetical protein\tK22302 dicC; transcriptional repressor of cell division inhibition gene dicB"
				},
				{
					"name":"APECO1_3398 ygiV; putative transcriptional regulator\tK07471 ygiV; probable transcriptional regulator"
				}
				]
			}
			]
		}
		]
	}
	]
}