{
	"name":"ecz03400",
	"children":[
	{
		"name":"Eukaryotic type",
		"children":[
		{
			"name":"SSBR (single strand breaks repair)",
			"children":[
			{
				"name":"Direct repair",
				"children":[
				{
					"name":"ECS88_1477 ogt; O-6-alkylguanine-DNA:cysteine-protein methyltransferase\tK00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]"
				},
				{
					"name":"ECS88_0736 phr; deoxyribodipyrimidine photolyase, FAD-binding\tK01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]"
				}
				]
			},
			{
				"name":"BER (base exicision repair)",
				"children":[
				{
					"name":"DNA glycosylases",
					"children":[
					{
						"name":"ECS88_2754 ung; uracil-DNA-glycosylase\tK03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]"
					},
					{
						"name":"ECS88_3244 mutY; adenine DNA glycosylase\tK03575 mutY; A\/G-specific adenine glycosylase [EC:3.2.2.31]"
					},
					{
						"name":"ECS88_1681 nth; DNA glycosylase and apyrimidinic (AP) lyase (endonuclease III)\tK10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]"
					}
					]
				},
				{
					"name":"AP endonucleases"
				},
				{
					"name":"Long Patch-BER factors",
					"children":[
					{
						"name":"DNA polymerase delta complex"
					},
					{
						"name":"DNA polymerase epsilon complex"
					}
					]
				},
				{
					"name":"Short Patch-BER factors"
				},
				{
					"name":"Other BER factors"
				}
				]
			},
			{
				"name":"NER (nucleotide excision repair)",
				"children":[
				{
					"name":"GGR (global genome repair) factors",
					"children":[
					{
						"name":"XPC-HR23B-CETN2 complex"
					},
					{
						"name":"Cul4-DDB2 complex"
					},
					{
						"name":"NER4 complex"
					}
					]
				},
				{
					"name":"TCR (transcription coupled repair) factors",
					"children":[
					{
						"name":"DNA-directed RNA polymerase II complex"
					},
					{
						"name":"Cul4-CSA complex"
					},
					{
						"name":"Other TCR factor"
					}
					]
				},
				{
					"name":"TFIIH complex"
				},
				{
					"name":"RPA (replication factor A)"
				},
				{
					"name":"Other NER factors"
				}
				]
			},
			{
				"name":"MMR (mismatch excision repair)",
				"children":[
				{
					"name":"Mismatch and loop recognition factors"
				},
				{
					"name":"MutL homologs"
				},
				{
					"name":"DNA polymerase delta complex"
				},
				{
					"name":"RPA (replication factor A)"
				},
				{
					"name":"RFC (replication factor C)"
				},
				{
					"name":"Other MMR factors"
				}
				]
			}
			]
		},
		{
			"name":"DSBR (double strand breaks repair)",
			"children":[
			{
				"name":"HR (homologous recombination)",
				"children":[
				{
					"name":"MRN(MRX) complex"
				},
				{
					"name":"BRCA1-core complex"
				},
				{
					"name":"BRCA1-A complex"
				},
				{
					"name":"BRCA1-B complex"
				},
				{
					"name":"BRCA1-C complex"
				},
				{
					"name":"BRCA complex"
				},
				{
					"name":"RecA family proteins"
				},
				{
					"name":"Rad52 family proteins"
				},
				{
					"name":"Rad54 family proteins"
				},
				{
					"name":"RecQ family DNA helicases"
				},
				{
					"name":"Bloom's syndrome complex (BTR)"
				},
				{
					"name":"RPA (replication factor A)"
				},
				{
					"name":"Protein phosphatase 4"
				},
				{
					"name":"AP-5 complex"
				},
				{
					"name":"SMC5-SMC6 complex"
				},
				{
					"name":"Other HR factors"
				}
				]
			},
			{
				"name":"NHEJ (non-homologous end-joining)",
				"children":[
				{
					"name":"DNA-PK complex"
				},
				{
					"name":"MRX complex"
				},
				{
					"name":"DNA Ligase 4 complex"
				},
				{
					"name":"X-family DNA polymerases"
				},
				{
					"name":"Other NHEJ factors"
				}
				]
			},
			{
				"name":"FA (Fanconi anemia) pathway",
				"children":[
				{
					"name":"FA core complex"
				},
				{
					"name":"FA core complex binding factors"
				},
				{
					"name":"Bloom's syndrome complex (BTR)"
				},
				{
					"name":"FANCD2-I complex"
				},
				{
					"name":"Downstream FA components"
				},
				{
					"name":"Other FA pathway factors"
				}
				]
			},
			{
				"name":"Other DSBR factors",
				"children":[
				{
					"name":"Protein phosphatase 6"
				},
				{
					"name":"Ubiquitin ligases"
				},
				{
					"name":"Others"
				}
				]
			}
			]
		},
		{
			"name":"TLS (translesion DNA synthesis) factors",
			"children":[
			{
				"name":"Y-family DNA polymerases"
			},
			{
				"name":"B-family DNA polymerases"
			},
			{
				"name":"A-family DNA polymerase"
			},
			{
				"name":"Rad6 epistasis group"
			},
			{
				"name":"Other TLS factors"
			}
			]
		},
		{
			"name":"Check point factors",
			"children":[
			{
				"name":"Rad9-Hus1-Rad1 complex"
			},
			{
				"name":"HRAD17(Rad24)-RFC complex"
			},
			{
				"name":"Rad17-Mec3-Ddc1 complex"
			},
			{
				"name":"FPC (fork protection complex)"
			},
			{
				"name":"Triple T complex"
			},
			{
				"name":"BAG6-UBL4A-GET4 complex"
			},
			{
				"name":"SOSS complex"
			},
			{
				"name":"Other check point factors"
			}
			]
		},
		{
			"name":"Other factors with a suspected DNA repair function",
			"children":[
			{
				"name":"DNA polymerases"
			},
			{
				"name":"Nucleases"
			},
			{
				"name":"Helicases"
			},
			{
				"name":"PSO4 complex"
			},
			{
				"name":"Modulation of nucleotide pools",
				"children":[
				{
					"name":"ECS88_0103 mutT; nucleoside triphosphate pyrophosphohydrolase, marked preference for dGTP\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]"
				},
				{
					"name":"ECS88_4054 dut; deoxyuridinetriphosphatase\tK01520 dut; dUTP diphosphatase [EC:3.6.1.23]"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic type",
		"children":[
		{
			"name":"SSBR (single strand breaks repair)",
			"children":[
			{
				"name":"Direct repair",
				"children":[
				{
					"name":"ECS88_1477 ogt; O-6-alkylguanine-DNA:cysteine-protein methyltransferase\tK00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]"
				},
				{
					"name":"ECS88_2361 ada; fused DNA-binding transcriptional dual regulator; O6-methylguanine-DNA methyltransferase\tK10778 ada; AraC family transcriptional regulator, regulatory protein of adaptative response \/ methylated-DNA-[protein]-cysteine methyltransferase [EC:2.1.1.63]"
				},
				{
					"name":"ECS88_0736 phr; deoxyribodipyrimidine photolyase, FAD-binding\tK01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]"
				},
				{
					"name":"ECS88_2360 alkB; oxidative demethylase of N1-methyladenine or N3-methylcytosine DNA lesions\tK03919 alkB; DNA oxidative demethylase [EC:1.14.11.33]"
				}
				]
			},
			{
				"name":"BER (base exicision repair)",
				"children":[
				{
					"name":"DNA glycosylases",
					"children":[
					{
						"name":"ECS88_2754 ung; uracil-DNA-glycosylase\tK03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]"
					},
					{
						"name":"ECS88_3466 ygjF; G\/U mismatch-specific DNA glycosylase\tK03649 mug; double-stranded uracil-DNA glycosylase [EC:3.2.2.28]"
					},
					{
						"name":"ECS88_2167 alkA; 3-methyl-adenine DNA glycosylase II\tK01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]"
					},
					{
						"name":"ECS88_3244 mutY; adenine DNA glycosylase\tK03575 mutY; A\/G-specific adenine glycosylase [EC:3.2.2.31]"
					},
					{
						"name":"ECS88_3968 tag; 3-methyl-adenine DNA glycosylase I, constitutive\tK01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]"
					},
					{
						"name":"ECS88_4049 mutM; formamidopyrimidine\/5-formyluracil\/5-hydroxymethyluracil DNA glycosylase\tK10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]"
					},
					{
						"name":"ECS88_0742 nei; endonuclease VIII; 5-formyluracil\/5-hydroxymethyluracil DNA glycosylase\tK05522 nei; endonuclease VIII [EC:3.2.2.- 4.2.99.18]"
					},
					{
						"name":"ECS88_1681 nth; DNA glycosylase and apyrimidinic (AP) lyase (endonuclease III)\tK10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]"
					}
					]
				},
				{
					"name":"AP endonucleases",
					"children":[
					{
						"name":"ECS88_1801 xthA; exonuclease III\tK01142 xthA; exodeoxyribonuclease III [EC:3.1.11.2]"
					},
					{
						"name":"ECS88_2308 nfo; endonuclease IV with intrinsic 3'-5' exonuclease activity\tK01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]"
					},
					{
						"name":"ECS88_4459 nfi; endonuclease V\tK05982 nfi; deoxyribonuclease V [EC:3.1.21.7]"
					}
					]
				},
				{
					"name":"RecJ",
					"children":[
					{
						"name":"ECS88_3172 recJ; ssDNA exonuclease, 5'--> 3'-specific\tK07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]"
					}
					]
				},
				{
					"name":"DNA ligase",
					"children":[
					{
						"name":"ECS88_2601 ligA; DNA ligase, NAD(+)-dependent\tK01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]"
					},
					{
						"name":"ECS88_4061 ligB; DNA ligase, NAD(+)-dependent\tK01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]"
					}
					]
				},
				{
					"name":"DNA polymerase I",
					"children":[
					{
						"name":"ECS88_4313 polA; fused DNA polymerase I 5'->3' exonuclease; 3'->5' polymerase; 3'->5' exonuclease\tK02335 polA; DNA polymerase I [EC:2.7.7.7]"
					}
					]
				}
				]
			},
			{
				"name":"NER (nucleotide excision repair)",
				"children":[
				{
					"name":"GGR (global genome repair) factors",
					"children":[
					{
						"name":"ECS88_4547 uvrA; ATPase and DNA damage recognition protein of nucleotide excision repair excinuclease UvrABC\tK03701 uvrA; excinuclease ABC subunit A"
					},
					{
						"name":"ECS88_0796 uvrB; excinulease of nucleotide excision repair, DNA damage recognition component\tK03702 uvrB; excinuclease ABC subunit B"
					},
					{
						"name":"ECS88_1967 uvrC; excinuclease UvrABC, endonuclease subunit\tK03703 uvrC; excinuclease ABC subunit C"
					},
					{
						"name":"ECS88_1793 ydjQ; endonuclease of nucleotide excision repair\tK05984 cho; excinuclease Cho [EC:3.1.25.-]"
					},
					{
						"name":"ECS88_4239 uvrD; DNA-dependent ATPase I and helicase II\tK03657 uvrD; ATP-dependent DNA helicase UvrD\/PcrA [EC:5.6.2.4]"
					},
					{
						"name":"ECS88_4313 polA; fused DNA polymerase I 5'->3' exonuclease; 3'->5' polymerase; 3'->5' exonuclease\tK02335 polA; DNA polymerase I [EC:2.7.7.7]"
					},
					{
						"name":"ECS88_2601 ligA; DNA ligase, NAD(+)-dependent\tK01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]"
					},
					{
						"name":"ECS88_4061 ligB; DNA ligase, NAD(+)-dependent\tK01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]"
					}
					]
				},
				{
					"name":"TCR (transcription coupled repair) factors",
					"children":[
					{
						"name":"DNA-directed RNA polymerase complex (RNAP)",
						"children":[
						{
							"name":"ECS88_4448 rpoB; RNA polymerase, beta subunit\tK03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]"
						},
						{
							"name":"ECS88_4449 rpoC; RNA polymerase, beta prime subunit\tK03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]"
						},
						{
							"name":"ECS88_3683 rpoA; RNA polymerase, alpha subunit\tK03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]"
						},
						{
							"name":"ECS88_4064 rpoZ; RNA polymerase, omega subunit\tK03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]"
						}
						]
					},
					{
						"name":"TRCF (transcription-repair coupling factor)",
						"children":[
						{
							"name":"ECS88_1128 mfd; transcription-repair coupling factor\tK03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]"
						}
						]
					}
					]
				}
				]
			},
			{
				"name":"MMR (mismatch excision repair)",
				"children":[
				{
					"name":"Mismatch and loop recognition factors",
					"children":[
					{
						"name":"ECS88_3000 mutS; methyl-directed mismatch repair protein\tK03555 mutS; DNA mismatch repair protein MutS"
					}
					]
				},
				{
					"name":"Molecular matchmaker",
					"children":[
					{
						"name":"ECS88_4756 mutL; methyl-directed mismatch repair protein\tK03572 mutL; DNA mismatch repair protein MutL"
					}
					]
				},
				{
					"name":"Strand discrimination factor",
					"children":[
					{
						"name":"ECS88_3126 mutH; methyl-directed mismatch repair protein\tK03573 mutH; DNA mismatch repair protein MutH"
					}
					]
				},
				{
					"name":"DNA exonucleases",
					"children":[
					{
						"name":"ECS88_2110 sbcB; exonuclease I\tK01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]"
					},
					{
						"name":"ECS88_2681 xseA; exonuclease VII, large subunit\tK03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]"
					},
					{
						"name":"ECS88_0417 xseB; exonuclease VII small subunit\tK03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]"
					},
					{
						"name":"ECS88_1898 exoX; DNA exonuclease X\tK10857 exoX; exodeoxyribonuclease X [EC:3.1.11.-]"
					}
					]
				},
				{
					"name":"DNA polymerase III holoenzyme",
					"children":[
					{
						"name":"ECS88_0195 dnaE; DNA polymerase III alpha subunit\tK02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]"
					},
					{
						"name":"ECS88_4124 dnaN; DNA polymerase III, beta subunit\tK02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]"
					},
					{
						"name":"ECS88_4846 holC; DNA polymerase III, chi subunit\tK02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7]"
					},
					{
						"name":"ECS88_0682 holA; DNA polymerase III, delta subunit\tK02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]"
					},
					{
						"name":"ECS88_1113 holB; DNA polymerase III, delta prime subunit\tK02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]"
					},
					{
						"name":"ECS88_0230 dnaQ; DNA polymerase III epsilon subunit\tK02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]"
					},
					{
						"name":"ECS88_p0103 yacC; putative exoribonuclease YacC\tK02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]"
					},
					{
						"name":"ECS88_0467 dnaX; DNA polymerase III\/DNA elongation factor III, tau and gamma subunits\tK02343 dnaX; DNA polymerase III subunit gamma\/tau [EC:2.7.7.7]"
					},
					{
						"name":"ECS88_4993 holD; DNA polymerase III, psi subunit\tK02344 holD; DNA polymerase III subunit psi [EC:2.7.7.7]"
					},
					{
						"name":"ECS88_1896 holE; DNA polymerase III, theta subunit\tK02345 holE; DNA polymerase III subunit theta [EC:2.7.7.7]"
					}
					]
				},
				{
					"name":"DNA ligase",
					"children":[
					{
						"name":"ECS88_2601 ligA; DNA ligase, NAD(+)-dependent\tK01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]"
					},
					{
						"name":"ECS88_4061 ligB; DNA ligase, NAD(+)-dependent\tK01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]"
					}
					]
				},
				{
					"name":"Other MMR factors",
					"children":[
					{
						"name":"ECS88_4239 uvrD; DNA-dependent ATPase I and helicase II\tK03657 uvrD; ATP-dependent DNA helicase UvrD\/PcrA [EC:5.6.2.4]"
					},
					{
						"name":"ECS88_4548 ssb; Single-stranded DNA-binding protein\tK03111 ssb; single-strand DNA-binding protein"
					},
					{
						"name":"ECS88_p0050 ssb; Single-stranded DNA-binding protein\tK03111 ssb; single-strand DNA-binding protein"
					},
					{
						"name":"ECS88_2842 dam; Site-specific DNA-methyltransferase (adenine-specific)\tK06223 dam; DNA adenine methylase [EC:2.1.1.72]"
					},
					{
						"name":"ECS88_3772 dam; DNA adenine methylase\tK06223 dam; DNA adenine methylase [EC:2.1.1.72]"
					},
					{
						"name":"ECS88_2013 vsr; DNA mismatch endonuclease of very short patch repair\tK07458 vsr; DNA mismatch endonuclease, patch repair protein [EC:3.1.-.-]"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"DSBR (double strand breaks repair)",
			"children":[
			{
				"name":"HR (homologous recombination)",
				"children":[
				{
					"name":"RecBC pathway proteins",
					"children":[
					{
						"name":"ECS88_3115 recB; exonuclease V (RecBCD complex), beta subunit\tK03582 recB; exodeoxyribonuclease V beta subunit [EC:3.1.11.5]"
					},
					{
						"name":"ECS88_3117 recC; exonuclease V (RecBCD complex), gamma chain\tK03583 recC; exodeoxyribonuclease V gamma subunit [EC:3.1.11.5]"
					},
					{
						"name":"ECS88_3114 recD; exonuclease V (RecBCD complex), alpha chain\tK03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]"
					},
					{
						"name":"ECS88_2962 recA; DNA strand exchange and recombination protein with protease and nuclease activity\tK03553 recA; recombination protein RecA"
					},
					{
						"name":"ECS88_1918 ruvA; component of RuvABC resolvasome, regulatory subunit\tK03550 ruvA; holliday junction DNA helicase RuvA"
					},
					{
						"name":"ECS88_1917 ruvB; ATP-dependent DNA helicase, component of RuvABC resolvasome\tK03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]"
					},
					{
						"name":"ECS88_1921 ruvC; component of RuvABC resolvasome, endonuclease\tK01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]"
					},
					{
						"name":"ECS88_0550 putative Crossover junction endodeoxyribonuclease\tK01160 rusA; crossover junction endodeoxyribonuclease RusA [EC:3.1.21.10]"
					},
					{
						"name":"ECS88_1181 rusA; endonuclease RUS; DLP12 prophage\tK01160 rusA; crossover junction endodeoxyribonuclease RusA [EC:3.1.21.10]"
					},
					{
						"name":"ECS88_1347 putative crossover junction endodeoxyribonuclease rusA (Holliday junction nuclease rusA) (Holliday juction resolvase) (Gp67)\tK01160 rusA; crossover junction endodeoxyribonuclease RusA [EC:3.1.21.10]"
					},
					{
						"name":"ECS88_2528 rusA; crossover junction endodeoxyribonuclease\tK01160 rusA; crossover junction endodeoxyribonuclease RusA [EC:3.1.21.10]"
					},
					{
						"name":"ECS88_2899 rusA; Crossover junction endodeoxyribonuclease\tK01160 rusA; crossover junction endodeoxyribonuclease RusA [EC:3.1.21.10]"
					},
					{
						"name":"ECS88_5012 Crossover junction endodeoxyribonuclease from phage origin\tK01160 rusA; crossover junction endodeoxyribonuclease RusA [EC:3.1.21.10]"
					},
					{
						"name":"ECS88_4385 priA; Primosome factor n' (replication factor Y)\tK04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]"
					},
					{
						"name":"ECS88_4787 priB; primosomal protein N\tK02686 priB; primosomal replication protein N"
					},
					{
						"name":"ECS88_0464 priC; primosomal replication protein N''\tK04067 priC; primosomal replication protein N''"
					},
					{
						"name":"ECS88_4983 dnaT; DNA biosynthesis protein (primosomal protein I)\tK02317 dnaT; DNA replication protein DnaT"
					},
					{
						"name":"ECS88_2110 sbcB; exonuclease I\tK01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]"
					},
					{
						"name":"ECS88_0391 sbcC; exonuclease, dsDNA, ATP-dependent\tK03546 sbcC; DNA repair protein SbcC\/Rad50"
					},
					{
						"name":"ECS88_0392 sbcD; exonuclease, dsDNA, ATP-dependent\tK03547 sbcD; DNA repair protein SbcD\/Mre11"
					}
					]
				},
				{
					"name":"RecFOR pathway proteins",
					"children":[
					{
						"name":"ECS88_2962 recA; DNA strand exchange and recombination protein with protease and nuclease activity\tK03553 recA; recombination protein RecA"
					},
					{
						"name":"ECS88_5070 radA; repair protein radA homolog\tK04485 radA; DNA repair protein RadA\/Sms"
					},
					{
						"name":"ECS88_4123 recF; gap repair protein\tK03629 recF; DNA replication and repair protein RecF"
					},
					{
						"name":"ECS88_4067 recG; ATP-dependent DNA helicase\tK03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]"
					},
					{
						"name":"ECS88_3172 recJ; ssDNA exonuclease, 5'--> 3'-specific\tK07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]"
					},
					{
						"name":"ECS88_2738 recO; gap repair protein\tK03584 recO; DNA repair protein RecO (recombination protein O)"
					},
					{
						"name":"ECS88_0469 recR; gap repair protein\tK06187 recR; recombination protein RecR"
					},
					{
						"name":"ECS88_2802 recN; recombination and repair protein\tK03631 recN; DNA repair protein RecN (Recombination protein N)"
					},
					{
						"name":"ECS88_0388 rdgC; DNA-binding protein, non-specific\tK03554 rdgC; recombination associated protein RdgC"
					},
					{
						"name":"ECS88_1918 ruvA; component of RuvABC resolvasome, regulatory subunit\tK03550 ruvA; holliday junction DNA helicase RuvA"
					},
					{
						"name":"ECS88_1917 ruvB; ATP-dependent DNA helicase, component of RuvABC resolvasome\tK03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]"
					},
					{
						"name":"ECS88_1921 ruvC; component of RuvABC resolvasome, endonuclease\tK01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]"
					}
					]
				},
				{
					"name":"AddAB pathway proteins"
				},
				{
					"name":"Other HR factor",
					"children":[
					{
						"name":"ECS88_0905 conserved hypothetical protein, CRISPR-associated protein\tK15342 cas1; CRISP-associated protein Cas1"
					},
					{
						"name":"ECS88_2333 yejH; putative nucleic acid ATP-dependent helicase\tK19789 radD; DNA repair protein RadD"
					}
					]
				},
				{
					"name":"Archaeal homologous recombinant proteins",
					"children":[
					{
						"name":"ECS88_0391 sbcC; exonuclease, dsDNA, ATP-dependent\tK03546 sbcC; DNA repair protein SbcC\/Rad50"
					},
					{
						"name":"ECS88_0392 sbcD; exonuclease, dsDNA, ATP-dependent\tK03547 sbcD; DNA repair protein SbcD\/Mre11"
					},
					{
						"name":"ECS88_4850 yjgR; putative ATPase\tK06915 herA; DNA double-strand break repair helicase HerA and related ATPase"
					}
					]
				}
				]
			},
			{
				"name":"NHEJ (non-homologous end-joining)",
				"children":[
				{
					"name":"Two-component NHEJ DNA repair complex"
				},
				{
					"name":"SHIIR (short-homology-independent illegitimate recombination)",
					"children":[
					{
						"name":"Facilitator",
						"children":[
						{
							"name":"ECS88_2379 gyrA; DNA gyrase (type II topoisomerase), subunit A\tK02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]"
						},
						{
							"name":"ECS88_4122 gyrB; DNA gyrase, subunit B\tK02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]"
						},
						{
							"name":"ECS88_1412 topA; DNA topoisomerase I, omega subunit\tK03168 topA; DNA topoisomerase I [EC:5.6.2.1]"
						}
						]
					},
					{
						"name":"Supressor",
						"children":[
						{
							"name":"ECS88_4461 hupA; HU, DNA-binding transcriptional regulator, alpha subunit\tK05787 hupA; DNA-binding protein HU-alpha"
						},
						{
							"name":"ECS88_0437 hupB; HU, DNA-binding transcriptional regulator, beta subunit\tK03530 hupB; DNA-binding protein HU-beta"
						}
						]
					}
					]
				},
				{
					"name":"SHDIR (short-homology-dependent illegitimate recombination)",
					"children":[
					{
						"name":"RecET pathway",
						"children":[
						{
							"name":"ECS88_3172 recJ; ssDNA exonuclease, 5'--> 3'-specific\tK07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]"
						},
						{
							"name":"ECS88_2738 recO; gap repair protein\tK03584 recO; DNA repair protein RecO (recombination protein O)"
						},
						{
							"name":"ECS88_0469 recR; gap repair protein\tK06187 recR; recombination protein RecR"
						},
						{
							"name":"ECS88_2601 ligA; DNA ligase, NAD(+)-dependent\tK01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]"
						},
						{
							"name":"ECS88_4061 ligB; DNA ligase, NAD(+)-dependent\tK01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]"
						}
						]
					},
					{
						"name":"Facilitator",
						"children":[
						{
							"name":"ECS88_3646 fis; global DNA-binding transcriptional dual regulator\tK03557 fis; Fis family transcriptional regulator, factor for inversion stimulation protein"
						},
						{
							"name":"ECS88_1763 ihfA; integration host factor (IHF), DNA-binding protein, alpha subunit\tK04764 ihfA; integration host factor subunit alpha"
						},
						{
							"name":"ECS88_0940 ihfB; integration host factor (IHF), DNA-binding protein, beta subunit\tK05788 ihfB; integration host factor subunit beta"
						}
						]
					},
					{
						"name":"Supressor",
						"children":[
						{
							"name":"ECS88_2110 sbcB; exonuclease I\tK01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]"
						},
						{
							"name":"ECS88_4547 uvrA; ATPase and DNA damage recognition protein of nucleotide excision repair excinuclease UvrABC\tK03701 uvrA; excinuclease ABC subunit A"
						},
						{
							"name":"ECS88_0796 uvrB; excinulease of nucleotide excision repair, DNA damage recognition component\tK03702 uvrB; excinuclease ABC subunit B"
						},
						{
							"name":"ECS88_1305 hns; global nucleic acid-binding transcriptional dual regulator H-NS\tK03746 hns; DNA-binding protein H-NS"
						}
						]
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"TLS (translesion DNA synthesis) factors",
			"children":[
			{
				"name":"Y-family DNA polymerases",
				"children":[
				{
					"name":"ECS88_0266 dinB; DNA polymerase IV\tK02346 dinB; DNA polymerase IV [EC:2.7.7.7]"
				},
				{
					"name":"ECS88_1247 umuC; DNA polymerase V, subunit C\tK03502 umuC; DNA polymerase V"
				},
				{
					"name":"ECS88_1246 umuD; DNA polymerase V, subunit D\tK03503 umuD; DNA polymerase V [EC:3.4.21.-]"
				}
				]
			},
			{
				"name":"Other SOS response factors",
				"children":[
				{
					"name":"ECS88_2962 recA; DNA strand exchange and recombination protein with protease and nuclease activity\tK03553 recA; recombination protein RecA"
				},
				{
					"name":"ECS88_0549 putative LexA repressor\tK01356 lexA; repressor LexA [EC:3.4.21.88]"
				},
				{
					"name":"ECS88_2900 putative regulatory protein; lexA-binding domain\tK01356 lexA; repressor LexA [EC:3.4.21.88]"
				},
				{
					"name":"ECS88_4517 lexA; DNA-binding transcriptional repressor of SOS regulon\tK01356 lexA; repressor LexA [EC:3.4.21.88]"
				},
				{
					"name":"ECS88_5011 conserved hypothetical protein from phage origin with LexA DNA binding domain\tK01356 lexA; repressor LexA [EC:3.4.21.88]"
				},
				{
					"name":"ECS88_2802 recN; recombination and repair protein\tK03631 recN; DNA repair protein RecN (Recombination protein N)"
				},
				{
					"name":"ECS88_0063 polB; DNA polymerase II\tK02336 polB; DNA polymerase II [EC:2.7.7.7]"
				},
				{
					"name":"ECS88_4548 ssb; Single-stranded DNA-binding protein\tK03111 ssb; single-strand DNA-binding protein"
				},
				{
					"name":"ECS88_p0050 ssb; Single-stranded DNA-binding protein\tK03111 ssb; single-strand DNA-binding protein"
				},
				{
					"name":"ECS88_4059 dinD; DNA-damage-inducible protein\tK14623 dinD; DNA-damage-inducible protein D"
				},
				{
					"name":"ECS88_1075 dinI; DNA damage-inducible protein I\tK12149 dinI; DNA-damage-inducible protein I"
				},
				{
					"name":"ECS88_2838 putative DinI-like damage-inducible protein\tK12149 dinI; DNA-damage-inducible protein I"
				},
				{
					"name":"ECS88_5053 DNA damage-inducible protein in prophage (dinI-like)\tK12149 dinI; DNA-damage-inducible protein I"
				},
				{
					"name":"ECS88_2961 recX; regulatory protein for RecA\tK03565 recX; regulatory protein"
				},
				{
					"name":"ECS88_3798 yhgA; putative transposase\tK01157 rpnA; recombination-promoting nuclease RpnA [EC:3.1.21.-]"
				},
				{
					"name":"ECS88_2452 yfcI; putative transposase\tK24087 rpnB; recombination-promoting nuclease RpnB [EC:3.1.21.-]"
				},
				{
					"name":"ECS88_0142 yadD; putative transposase\tK24088 rpnC; recombination-promoting nuclease RpnC [EC:3.1.21.-]"
				},
				{
					"name":"ECS88_4962 Conserved hypothetical protein, putative transposase\tK24089 rpnD; recombination-promoting nuclease RpnD [EC:3.1.21.-]"
				},
				{
					"name":"ECS88_2391 yfaD; Conserved hypothetical protein, putative transposase\tK24090 rpnE; recombination-promoting nuclease RpnE"
				}
				]
			}
			]
		},
		{
			"name":"Other factors with a suspected DNA repair function",
			"children":[
			{
				"name":"DNA polymerase"
			},
			{
				"name":"DNA helicases",
				"children":[
				{
					"name":"ECS88_4199 rep; DNA helicase and single-stranded DNA-dependent ATPase\tK03656 rep; ATP-dependent DNA helicase Rep [EC:5.6.2.4]"
				},
				{
					"name":"ECS88_0984 helD; DNA helicase IV\tK03658 helD; DNA helicase IV [EC:5.6.2.4]"
				},
				{
					"name":"ECS88_0817 dinG; ATP-dependent DNA helicase\tK03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]"
				},
				{
					"name":"ECS88_1860 yoaA; putative ATP-dependent helicase\tK03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]"
				}
				]
			},
			{
				"name":"Modulation of nucleotide pools",
				"children":[
				{
					"name":"ECS88_0103 mutT; nucleoside triphosphate pyrophosphohydrolase, marked preference for dGTP\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]"
				},
				{
					"name":"ECS88_4054 dut; deoxyuridinetriphosphatase\tK01520 dut; dUTP diphosphatase [EC:3.6.1.23]"
				},
				{
					"name":"ECS88_2382 nrdA; ribonucleoside diphosphate reductase 1, alpha subunit\tK00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]"
				},
				{
					"name":"ECS88_2941 nrdE; ribonucleoside-diphosphate reductase 2, alpha subunit\tK00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]"
				},
				{
					"name":"ECS88_2383 nrdB; ribonucleoside diphosphate reductase 1, beta subunit, ferritin-like\tK00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]"
				},
				{
					"name":"ECS88_2942 nrdF; ribonucleoside-diphosphate reductase 2, beta subunit, ferritin-like\tK00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]"
				}
				]
			},
			{
				"name":"Others"
			}
			]
		}
		]
	}
	]
}