{
	"name":"egu03400",
	"children":[
	{
		"name":"Eukaryotic type",
		"children":[
		{
			"name":"SSBR (single strand breaks repair)",
			"children":[
			{
				"name":"Direct repair",
				"children":[
				{
					"name":"105060733 DNA oxidative demethylase ALKBH2 isoform X1\tK10859 ALKBH2; DNA oxidative demethylase [EC:1.14.11.33]"
				},
				{
					"name":"105055970 LOW QUALITY PROTEIN: DExH-box ATP-dependent RNA helicase DExH14\tK18663 ASCC3; activating signal cointegrator complex subunit 3 [EC:5.6.2.4]"
				},
				{
					"name":"105042716 deoxyribodipyrimidine photo-lyase isoform X2\tK01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]"
				}
				]
			},
			{
				"name":"BER (base exicision repair)",
				"children":[
				{
					"name":"DNA glycosylases",
					"children":[
					{
						"name":"105055388 uracil-DNA glycosylase, mitochondrial isoform X1\tK03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]"
					},
					{
						"name":"105058927 uracil-DNA glycosylase, mitochondrial\tK03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]"
					},
					{
						"name":"105053127 DNA-3-methyladenine glycosylase isoform X1\tK03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]"
					},
					{
						"name":"140858208 DNA-3-methyladenine glycosylase-like isoform X1\tK03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]"
					},
					{
						"name":"105051527 adenine DNA glycosylase\tK03575 mutY; A\/G-specific adenine glycosylase [EC:3.2.2.31]"
					},
					{
						"name":"105051819 LOW QUALITY PROTEIN: N-glycosylase\/DNA lyase OGG1\tK03660 OGG1; N-glycosylase\/DNA lyase [EC:3.2.2.- 4.2.99.18]"
					},
					{
						"name":"105039152 uncharacterized protein isoform X1\tK10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]"
					},
					{
						"name":"105051450 endonuclease III homolog 1, chloroplastic\tK10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]"
					}
					]
				},
				{
					"name":"AP endonucleases",
					"children":[
					{
						"name":"105055065 DNA-(apurinic or apyrimidinic site) endonuclease 2\tK10772 APEX2; AP endonuclease 2 [EC:3.1.11.2]"
					}
					]
				},
				{
					"name":"Long Patch-BER factors",
					"children":[
					{
						"name":"DNA polymerase delta complex",
						"children":[
						{
							"name":"105051804 LOW QUALITY PROTEIN: DNA polymerase delta catalytic subunit\tK02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]"
						},
						{
							"name":"105053504 DNA polymerase delta small subunit isoform X2\tK02328 POLD2; DNA polymerase delta subunit 2"
						},
						{
							"name":"105040593 uncharacterized protein isoform X1\tK03504 POLD3; DNA polymerase delta subunit 3"
						},
						{
							"name":"105053523 uncharacterized protein\tK03505 POLD4; DNA polymerase delta subunit 4"
						},
						{
							"name":"105059462 uncharacterized protein\tK03505 POLD4; DNA polymerase delta subunit 4"
						}
						]
					},
					{
						"name":"DNA polymerase epsilon complex",
						"children":[
						{
							"name":"105035197 LOW QUALITY PROTEIN: DNA polymerase epsilon catalytic subunit A\tK02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]"
						},
						{
							"name":"105041903 DNA polymerase epsilon subunit B\tK02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]"
						},
						{
							"name":"140856483 DNA polymerase epsilon subunit B-like\tK02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]"
						},
						{
							"name":"105033758 DNA polymerase II subunit B4 isoform X1\tK02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]"
						},
						{
							"name":"105049709 DNA polymerase II subunit B4\tK02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]"
						}
						]
					},
					{
						"name":"105046296 proliferating cell nuclear antigen\tK04802 PCNA; proliferating cell nuclear antigen"
					},
					{
						"name":"105050563 proliferating cell nuclear antigen\tK04802 PCNA; proliferating cell nuclear antigen"
					},
					{
						"name":"105054821 proliferating cell nuclear antigen isoform X2\tK04802 PCNA; proliferating cell nuclear antigen"
					},
					{
						"name":"105040125 flap endonuclease 1 isoform X1\tK04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]"
					},
					{
						"name":"105059737 flap endonuclease 1-A\tK04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]"
					},
					{
						"name":"105057784 DNA ligase 1 isoform X1\tK10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]"
					},
					{
						"name":"105060442 DNA ligase 1 isoform X1\tK10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]"
					}
					]
				},
				{
					"name":"Short Patch-BER factors",
					"children":[
					{
						"name":"105047883 DNA-repair protein XRCC1 isoform X1\tK10803 XRCC1; DNA-repair protein XRCC1"
					}
					]
				},
				{
					"name":"Other BER factors",
					"children":[
					{
						"name":"105052040 tyrosyl-DNA phosphodiesterase 1 isoform X1\tK10862 TDP1; tyrosyl-DNA phosphodiesterase 1 [EC:3.1.4.-]"
					},
					{
						"name":"105057122 transcription factor bHLH140 isoform X1\tK10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]"
					},
					{
						"name":"105047531 LOW QUALITY PROTEIN: polynucleotide 3'-phosphatase ZDP\tK08073 PNKP; bifunctional polynucleotide phosphatase\/kinase [EC:3.1.3.32 2.7.1.78]"
					},
					{
						"name":"105039164 DNA polymerase lambda isoform X1\tK03512 POLL; DNA polymerase lambda [EC:2.7.7.7 4.2.99.-]"
					},
					{
						"name":"105043061 LOW QUALITY PROTEIN: poly [ADP-ribose] polymerase 1\tK24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30]"
					},
					{
						"name":"105053578 LOW QUALITY PROTEIN: poly [ADP-ribose] polymerase 1-like\tK24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30]"
					},
					{
						"name":"105052529 poly [ADP-ribose] polymerase 2 isoform X1\tK28005 PARP2; poly [ADP-ribose] polymerase 2 [EC:2.4.2.30]"
					},
					{
						"name":"105033868 LOW QUALITY PROTEIN: protein ADP-ribosyltransferase PARP3\tK10798 PARP3_4; protein mono-ADP-ribosyltransferase 3\/4 [EC:2.4.2.-]"
					}
					]
				}
				]
			},
			{
				"name":"NER (nucleotide excision repair)",
				"children":[
				{
					"name":"GGR (global genome repair) factors",
					"children":[
					{
						"name":"XPC-HR23B-CETN2 complex",
						"children":[
						{
							"name":"105053183 DNA repair protein RAD4 isoform X1\tK10838 XPC; xeroderma pigmentosum group C-complementing protein"
						},
						{
							"name":"105034003 ubiquitin receptor RAD23d isoform X1\tK10839 RAD23; UV excision repair protein RAD23"
						},
						{
							"name":"105041073 ubiquitin receptor RAD23c isoform X1\tK10839 RAD23; UV excision repair protein RAD23"
						},
						{
							"name":"105048512 ubiquitin receptor RAD23d isoform X1\tK10839 RAD23; UV excision repair protein RAD23"
						},
						{
							"name":"105050755 ubiquitin receptor RAD23b\tK10839 RAD23; UV excision repair protein RAD23"
						}
						]
					},
					{
						"name":"Cul4-DDB2 complex",
						"children":[
						{
							"name":"105056281 RING-box protein 1a\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
						},
						{
							"name":"105058733 RING-box protein 1a\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
						},
						{
							"name":"105046728 cullin-4\tK10609 CUL4; cullin 4"
						},
						{
							"name":"105059632 cullin-4-like isoform X1\tK10609 CUL4; cullin 4"
						},
						{
							"name":"105033280 DNA damage-binding protein 1a\tK10610 DDB1; DNA damage-binding protein 1"
						},
						{
							"name":"105059787 DNA damage-binding protein 1a\tK10610 DDB1; DNA damage-binding protein 1"
						},
						{
							"name":"105046232 DNA damage-binding protein 2 isoform X1\tK10140 DDB2; DNA damage-binding protein 2"
						}
						]
					},
					{
						"name":"NER4 complex",
						"children":[
						{
							"name":"105041840 uncharacterized protein isoform X1\tK15082 RAD7; DNA repair protein RAD7"
						},
						{
							"name":"105058631 LOW QUALITY PROTEIN: uncharacterized protein\tK15082 RAD7; DNA repair protein RAD7"
						},
						{
							"name":"105051048 DNA repair protein RAD16 isoform X2\tK15083 RAD16; DNA repair protein RAD16"
						}
						]
					}
					]
				},
				{
					"name":"TCR (transcription coupled repair) factors",
					"children":[
					{
						"name":"DNA-directed RNA polymerase II complex",
						"children":[
						{
							"name":"105055141 DNA-directed RNA polymerase II subunit RPB1\tK03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]"
						},
						{
							"name":"105059668 DNA-directed RNA polymerase II subunit RPB1\tK03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]"
						},
						{
							"name":"105044174 LOW QUALITY PROTEIN: DNA-directed RNA polymerase II subunit RPB2\tK03010 RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]"
						},
						{
							"name":"105060985 DNA-directed RNA polymerases II, IV and V subunit 3 isoform X1\tK03011 RPB3; DNA-directed RNA polymerase II subunit RPB3"
						},
						{
							"name":"105058909 DNA-directed RNA polymerase II subunit 4\tK03012 RPB4; DNA-directed RNA polymerase II subunit RPB4"
						},
						{
							"name":"105060763 DNA-directed RNA polymerases IV and V subunit 4\tK03012 RPB4; DNA-directed RNA polymerase II subunit RPB4"
						},
						{
							"name":"105045456 DNA-directed RNA polymerases II and IV subunit 5A isoform X2\tK03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1"
						},
						{
							"name":"105045524 DNA-directed RNA polymerases II and IV subunit 5A\tK03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1"
						},
						{
							"name":"105045542 DNA-directed RNA polymerase V subunit 5A isoform X1\tK03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1"
						},
						{
							"name":"105050256 DNA-directed RNA polymerases II and IV subunit 5A\tK03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1"
						},
						{
							"name":"105051377 DNA-directed RNA polymerases II and IV subunit 5A\tK03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1"
						},
						{
							"name":"105043406 DNA-directed RNA polymerases II, IV and V subunit 6A\tK03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2"
						},
						{
							"name":"105059413 DNA-directed RNA polymerases II, IV and V subunit 6A isoform X1\tK03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2"
						},
						{
							"name":"105054705 DNA-directed RNA polymerase II subunit RPB7\tK03015 RPB7; DNA-directed RNA polymerase II subunit RPB7"
						},
						{
							"name":"105059347 DNA-directed RNA polymerase II subunit RPB7\tK03015 RPB7; DNA-directed RNA polymerase II subunit RPB7"
						},
						{
							"name":"105060651 DNA-directed RNA polymerases II, IV and V subunit 8B\tK03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3"
						},
						{
							"name":"105045041 DNA-directed RNA polymerases II, IV and V subunit 9A\tK03017 RPB9; DNA-directed RNA polymerase II subunit RPB9"
						},
						{
							"name":"105052594 DNA-directed RNA polymerases II, IV and V subunit 9A\tK03017 RPB9; DNA-directed RNA polymerase II subunit RPB9"
						},
						{
							"name":"105054337 DNA-directed RNA polymerases II, IV and V subunit 9A\tK03017 RPB9; DNA-directed RNA polymerase II subunit RPB9"
						},
						{
							"name":"105056699 DNA-directed RNA polymerases II, IV and V subunit 9A\tK03017 RPB9; DNA-directed RNA polymerase II subunit RPB9"
						},
						{
							"name":"140852427 DNA-directed RNA polymerases II, IV and V subunit 9A-like\tK03017 RPB9; DNA-directed RNA polymerase II subunit RPB9"
						},
						{
							"name":"140858108 DNA-directed RNA polymerases II, IV and V subunit 9A-like\tK03017 RPB9; DNA-directed RNA polymerase II subunit RPB9"
						},
						{
							"name":"109506288 DNA-directed RNA polymerase subunit 10-like protein\tK03007 RPABC5; DNA-directed RNA polymerases I, II, and III subunit RPABC5"
						},
						{
							"name":"105034621 DNA-directed RNA polymerases II, IV and V subunit 11-like\tK03008 RPB11; DNA-directed RNA polymerase II subunit RPB11"
						},
						{
							"name":"105053143 DNA-directed RNA polymerases II, IV and V subunit 11 isoform X1\tK03008 RPB11; DNA-directed RNA polymerase II subunit RPB11"
						},
						{
							"name":"105042794 DNA-directed RNA polymerases II, IV and V subunit 12\tK03009 RPABC4; DNA-directed RNA polymerases I, II, and III subunit RPABC4"
						}
						]
					},
					{
						"name":"Cul4-CSA complex",
						"children":[
						{
							"name":"105056281 RING-box protein 1a\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
						},
						{
							"name":"105058733 RING-box protein 1a\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
						},
						{
							"name":"105046728 cullin-4\tK10609 CUL4; cullin 4"
						},
						{
							"name":"105059632 cullin-4-like isoform X1\tK10609 CUL4; cullin 4"
						},
						{
							"name":"105033280 DNA damage-binding protein 1a\tK10610 DDB1; DNA damage-binding protein 1"
						},
						{
							"name":"105059787 DNA damage-binding protein 1a\tK10610 DDB1; DNA damage-binding protein 1"
						},
						{
							"name":"105035290 WD repeat-containing protein ATCSA-1 isoform X1\tK10570 ERCC8; DNA excision repair protein ERCC-8"
						}
						]
					},
					{
						"name":"Other TCR factor",
						"children":[
						{
							"name":"105051054 DNA excision repair protein CSB isoform X1\tK10841 ERCC6; DNA excision repair protein ERCC-6"
						},
						{
							"name":"105040903 UV-stimulated scaffold protein A homolog\tK23720 UVSSA; UV-stimulated scaffold protein A"
						},
						{
							"name":"105035215 transcription elongation factor 1 homolog\tK25829 ELOF1; transcription elongation factor 1"
						},
						{
							"name":"105041229 LOW QUALITY PROTEIN: transcription elongation factor 1 homolog\tK25829 ELOF1; transcription elongation factor 1"
						},
						{
							"name":"105047470 transcription elongation factor 1 homolog\tK25829 ELOF1; transcription elongation factor 1"
						},
						{
							"name":"105048089 transcription elongation factor 1 homolog\tK25829 ELOF1; transcription elongation factor 1"
						}
						]
					}
					]
				},
				{
					"name":"TFIIH complex",
					"children":[
					{
						"name":"105054955 general transcription and DNA repair factor IIH helicase\/translocase subunit XPB1 isoform X1\tK10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]"
					},
					{
						"name":"105039800 general transcription and DNA repair factor IIH helicase subunit XPD\tK10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]"
					},
					{
						"name":"105039254 general transcription and DNA repair factor IIH subunit TFB1-1 isoform X2\tK03141 TFIIH1; transcription initiation factor TFIIH subunit 1"
					},
					{
						"name":"105050366 general transcription and DNA repair factor IIH subunit TFB1-1 isoform X1\tK03141 TFIIH1; transcription initiation factor TFIIH subunit 1"
					},
					{
						"name":"105043197 general transcription factor IIH subunit 2\tK03142 TFIIH2; transcription initiation factor TFIIH subunit 2"
					},
					{
						"name":"105041337 LOW QUALITY PROTEIN: general transcription and DNA repair factor IIH subunit TFB4\tK03143 TFIIH3; transcription initiation factor TFIIH subunit 3"
					},
					{
						"name":"105059003 general transcription and DNA repair factor IIH subunit TFB2 isoform X1\tK03144 TFIIH4; transcription initiation factor TFIIH subunit 4"
					},
					{
						"name":"140850836 general transcription and DNA repair factor IIH subunit TFB2-like isoform X1\tK03144 TFIIH4; transcription initiation factor TFIIH subunit 4"
					},
					{
						"name":"105060439 cyclin-dependent kinase D-1\tK02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]"
					},
					{
						"name":"105033574 uncharacterized protein\tK10842 MNAT1; CDK-activating kinase assembly factor MAT1"
					},
					{
						"name":"105041348 uncharacterized protein\tK10842 MNAT1; CDK-activating kinase assembly factor MAT1"
					}
					]
				},
				{
					"name":"RPA (replication factor A)",
					"children":[
					{
						"name":"105044402 replication protein A 70 kDa DNA-binding subunit A\tK07466 RFA1; replication factor A1"
					},
					{
						"name":"105056091 LOW QUALITY PROTEIN: replication protein A 70 kDa DNA-binding subunit B\tK07466 RFA1; replication factor A1"
					},
					{
						"name":"109505580 replication protein A 70 kDa DNA-binding subunit A\tK07466 RFA1; replication factor A1"
					},
					{
						"name":"105035014 replication protein A 32 kDa subunit A\tK10739 RFA2; replication factor A2"
					},
					{
						"name":"105050800 replication protein A 32 kDa subunit B isoform X1\tK10739 RFA2; replication factor A2"
					},
					{
						"name":"105055410 replication protein A 32 kDa subunit A isoform X1\tK10739 RFA2; replication factor A2"
					},
					{
						"name":"105039914 replication protein A 14 kDa subunit\tK10740 RPA3; replication factor A3"
					},
					{
						"name":"105052578 replication protein A 14 kDa subunit\tK10740 RPA3; replication factor A3"
					}
					]
				},
				{
					"name":"Other NER factors",
					"children":[
					{
						"name":"105043469 DNA excision repair protein ERCC-1\tK10849 ERCC1; DNA excision repair protein ERCC-1"
					},
					{
						"name":"105043789 DNA repair endonuclease UVH1 isoform X1\tK10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]"
					},
					{
						"name":"105060440 DNA repair protein UVH3 isoform X1\tK10846 ERCC5; DNA excision repair protein ERCC-5"
					},
					{
						"name":"105057784 DNA ligase 1 isoform X1\tK10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]"
					},
					{
						"name":"105060442 DNA ligase 1 isoform X1\tK10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]"
					},
					{
						"name":"105040454 MMS19 nucleotide excision repair protein homolog\tK15075 MET18; DNA repair\/transcription protein MET18\/MMS19"
					},
					{
						"name":"105033040 protein CIA1\tK24730 CIAO1; cytosolic iron-sulfur protein assembly protein CIAO1"
					},
					{
						"name":"105043960 protein AE7\tK26403 CIAO2; cytosolic iron-sulfur assembly component 2"
					},
					{
						"name":"105053814 uncharacterized protein isoform X3\tK26403 CIAO2; cytosolic iron-sulfur assembly component 2"
					},
					{
						"name":"105060107 protein AE7-like 1 isoform X2\tK26403 CIAO2; cytosolic iron-sulfur assembly component 2"
					},
					{
						"name":"105060790 protein AE7-like 1 isoform X1\tK26403 CIAO2; cytosolic iron-sulfur assembly component 2"
					},
					{
						"name":"105056562 cullin-3A isoform X2\tK03869 CUL3; cullin 3"
					},
					{
						"name":"105058331 cullin-3A\tK03869 CUL3; cullin 3"
					},
					{
						"name":"105032609 uncharacterized protein isoform X2\tK03872 ELOC; elongin-C"
					},
					{
						"name":"105046342 uncharacterized protein\tK03872 ELOC; elongin-C"
					},
					{
						"name":"105032010 uncharacterized protein isoform X1\tK03873 ELOB; elongin-B"
					},
					{
						"name":"105049859 uncharacterized protein isoform X4\tK03873 ELOB; elongin-B"
					},
					{
						"name":"105058328 uncharacterized protein\tK15077 ELA1; elongin-A"
					}
					]
				}
				]
			},
			{
				"name":"MMR (mismatch excision repair)",
				"children":[
				{
					"name":"Mismatch and loop recognition factors",
					"children":[
					{
						"name":"105041044 DNA mismatch repair protein MSH2 isoform X1\tK08735 MSH2; DNA mismatch repair protein MSH2"
					},
					{
						"name":"105054823 DNA mismatch repair protein MSH3 isoform X1\tK08736 MSH3; DNA mismatch repair protein MSH3"
					},
					{
						"name":"105040286 DNA mismatch repair protein MSH7\tK08737 MSH6; DNA mismatch repair protein MSH6"
					},
					{
						"name":"105053216 LOW QUALITY PROTEIN: DNA mismatch repair protein MSH6\tK08737 MSH6; DNA mismatch repair protein MSH6"
					}
					]
				},
				{
					"name":"MutL homologs",
					"children":[
					{
						"name":"105038513 DNA mismatch repair protein MLH1 isoform X1\tK08734 MLH1; DNA mismatch repair protein MLH1"
					},
					{
						"name":"105039840 DNA mismatch repair protein PMS1 isoform X1\tK10858 PMS2; DNA mismatch repair protein PMS2"
					},
					{
						"name":"105055235 DNA mismatch repair protein MLH3 isoform X1\tK08739 MLH3; DNA mismatch repair protein MLH3"
					}
					]
				},
				{
					"name":"DNA polymerase delta complex",
					"children":[
					{
						"name":"105051804 LOW QUALITY PROTEIN: DNA polymerase delta catalytic subunit\tK02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]"
					},
					{
						"name":"105053504 DNA polymerase delta small subunit isoform X2\tK02328 POLD2; DNA polymerase delta subunit 2"
					},
					{
						"name":"105040593 uncharacterized protein isoform X1\tK03504 POLD3; DNA polymerase delta subunit 3"
					},
					{
						"name":"105053523 uncharacterized protein\tK03505 POLD4; DNA polymerase delta subunit 4"
					},
					{
						"name":"105059462 uncharacterized protein\tK03505 POLD4; DNA polymerase delta subunit 4"
					}
					]
				},
				{
					"name":"RPA (replication factor A)",
					"children":[
					{
						"name":"105044402 replication protein A 70 kDa DNA-binding subunit A\tK07466 RFA1; replication factor A1"
					},
					{
						"name":"105056091 LOW QUALITY PROTEIN: replication protein A 70 kDa DNA-binding subunit B\tK07466 RFA1; replication factor A1"
					},
					{
						"name":"109505580 replication protein A 70 kDa DNA-binding subunit A\tK07466 RFA1; replication factor A1"
					},
					{
						"name":"105035014 replication protein A 32 kDa subunit A\tK10739 RFA2; replication factor A2"
					},
					{
						"name":"105050800 replication protein A 32 kDa subunit B isoform X1\tK10739 RFA2; replication factor A2"
					},
					{
						"name":"105055410 replication protein A 32 kDa subunit A isoform X1\tK10739 RFA2; replication factor A2"
					},
					{
						"name":"105039914 replication protein A 14 kDa subunit\tK10740 RPA3; replication factor A3"
					},
					{
						"name":"105052578 replication protein A 14 kDa subunit\tK10740 RPA3; replication factor A3"
					}
					]
				},
				{
					"name":"RFC (replication factor C)",
					"children":[
					{
						"name":"105042420 replication factor C subunit 1 isoform X1\tK10754 RFC1; replication factor C subunit 1"
					},
					{
						"name":"105037415 replication factor C subunit 4\tK10755 RFC2_4; replication factor C subunit 2\/4"
					},
					{
						"name":"105051821 replication factor C subunit 2\tK10755 RFC2_4; replication factor C subunit 2\/4"
					},
					{
						"name":"140851747 replication factor C subunit 2\tK10755 RFC2_4; replication factor C subunit 2\/4"
					},
					{
						"name":"105036598 replication factor C subunit 3\tK10756 RFC3_5; replication factor C subunit 3\/5"
					},
					{
						"name":"105037514 replication factor C subunit 3\tK10756 RFC3_5; replication factor C subunit 3\/5"
					},
					{
						"name":"105053122 replication factor C subunit 3\tK10756 RFC3_5; replication factor C subunit 3\/5"
					},
					{
						"name":"140852096 replication factor C subunit 3\tK10756 RFC3_5; replication factor C subunit 3\/5"
					}
					]
				},
				{
					"name":"Other MMR factors",
					"children":[
					{
						"name":"105046296 proliferating cell nuclear antigen\tK04802 PCNA; proliferating cell nuclear antigen"
					},
					{
						"name":"105050563 proliferating cell nuclear antigen\tK04802 PCNA; proliferating cell nuclear antigen"
					},
					{
						"name":"105054821 proliferating cell nuclear antigen isoform X2\tK04802 PCNA; proliferating cell nuclear antigen"
					},
					{
						"name":"105041179 exonuclease 1\tK10746 EXO1; exonuclease 1 [EC:3.1.-.-]"
					},
					{
						"name":"105053866 exonuclease 1 isoform X1\tK10746 EXO1; exonuclease 1 [EC:3.1.-.-]"
					},
					{
						"name":"105057784 DNA ligase 1 isoform X1\tK10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]"
					},
					{
						"name":"105060442 DNA ligase 1 isoform X1\tK10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]"
					},
					{
						"name":"105052942 uncharacterized protein\tK24755 WDR76; WD repeat-containing protein 76"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"DSBR (double strand breaks repair)",
			"children":[
			{
				"name":"HR (homologous recombination)",
				"children":[
				{
					"name":"MRN(MRX) complex",
					"children":[
					{
						"name":"105033323 double-strand break repair protein MRE11 isoform X1\tK10865 MRE11; double-strand break repair protein MRE11"
					},
					{
						"name":"105052694 double-strand break repair protein MRE11 isoform X1\tK10865 MRE11; double-strand break repair protein MRE11"
					},
					{
						"name":"140858165 double-strand break repair protein MRE11-like\tK10865 MRE11; double-strand break repair protein MRE11"
					},
					{
						"name":"105049145 DNA repair protein RAD50 isoform X1\tK10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]"
					},
					{
						"name":"105042781 LOW QUALITY PROTEIN: nibrin homolog\tK10867 NBN; nibrin"
					}
					]
				},
				{
					"name":"BRCA1-core complex",
					"children":[
					{
						"name":"105044204 BRCA1-associated RING domain protein 1 isoform X1\tK10683 BARD1; BRCA1-associated RING domain protein 1"
					},
					{
						"name":"105046724 protein BREAST CANCER SUSCEPTIBILITY 1 homolog isoform X1\tK10683 BARD1; BRCA1-associated RING domain protein 1"
					},
					{
						"name":"105058864 LOW QUALITY PROTEIN: protein BREAST CANCER SUSCEPTIBILITY 1 homolog\tK10683 BARD1; BRCA1-associated RING domain protein 1"
					}
					]
				},
				{
					"name":"BRCA1-A complex",
					"children":[
					{
						"name":"105047998 uncharacterized protein\tK20776 BABAM; BRISC and BRCA1-A complex member 1"
					},
					{
						"name":"105059615 uncharacterized protein\tK12173 BRE; BRCA1-A complex subunit BRE"
					},
					{
						"name":"105044524 uncharacterized protein isoform X1\tK11864 BRCC3; BRCA1\/BRCA2-containing complex subunit 3 [EC:3.4.19.-]"
					}
					]
				},
				{
					"name":"BRCA1-B complex",
					"children":[
					{
						"name":"105055234 uncharacterized protein isoform X2\tK15362 BRIP1; fanconi anemia group J protein [EC:5.6.2.3]"
					},
					{
						"name":"105045060 LOW QUALITY PROTEIN: BRCT domain-containing protein At4g02110\tK10728 TOPBP1; topoisomerase (DNA) II binding protein 1"
					},
					{
						"name":"105051794 LOW QUALITY PROTEIN: uncharacterized protein\tK10728 TOPBP1; topoisomerase (DNA) II binding protein 1"
					}
					]
				},
				{
					"name":"BRCA1-C complex",
					"children":[
					{
						"name":"105033323 double-strand break repair protein MRE11 isoform X1\tK10865 MRE11; double-strand break repair protein MRE11"
					},
					{
						"name":"105052694 double-strand break repair protein MRE11 isoform X1\tK10865 MRE11; double-strand break repair protein MRE11"
					},
					{
						"name":"140858165 double-strand break repair protein MRE11-like\tK10865 MRE11; double-strand break repair protein MRE11"
					},
					{
						"name":"105049145 DNA repair protein RAD50 isoform X1\tK10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]"
					},
					{
						"name":"105042781 LOW QUALITY PROTEIN: nibrin homolog\tK10867 NBN; nibrin"
					}
					]
				},
				{
					"name":"BRCA complex",
					"children":[
					{
						"name":"105057159 protein BREAST CANCER SUSCEPTIBILITY 2 homolog B isoform X1\tK08775 BRCA2; breast cancer 2 susceptibility protein"
					},
					{
						"name":"105056665 DNA repair protein RAD51 homolog\tK04482 RAD51; DNA repair protein RAD51"
					},
					{
						"name":"105058584 LOW QUALITY PROTEIN: DNA repair protein RAD51 homolog\tK04482 RAD51; DNA repair protein RAD51"
					}
					]
				},
				{
					"name":"RecA family proteins",
					"children":[
					{
						"name":"105056665 DNA repair protein RAD51 homolog\tK04482 RAD51; DNA repair protein RAD51"
					},
					{
						"name":"105058584 LOW QUALITY PROTEIN: DNA repair protein RAD51 homolog\tK04482 RAD51; DNA repair protein RAD51"
					},
					{
						"name":"105059023 DNA repair protein RAD51 homolog 3 isoform X1\tK10870 RAD51L2; RAD51-like protein 2"
					},
					{
						"name":"105045740 DNA repair protein RAD51 homolog 4 isoform X2\tK10871 RAD51L3; RAD51-like protein 3"
					},
					{
						"name":"105037939 DNA repair protein XRCC2 homolog isoform X1\tK10879 XRCC2; DNA-repair protein XRCC2"
					},
					{
						"name":"105039627 DNA repair protein XRCC3 homolog isoform X1\tK10880 XRCC3; DNA-repair protein XRCC3"
					}
					]
				},
				{
					"name":"Rad52 family proteins",
					"children":[
					{
						"name":"105036234 LOW QUALITY PROTEIN: DNA repair RAD52-like protein 1, mitochondrial\tK26556 RAD52-1; DNA repair RAD52-like protein 1, mitochondrial"
					},
					{
						"name":"105034328 DNA repair RAD52-like protein 2, chloroplastic\tK26558 RAD52-2; DNA repair RAD52-like protein 2, chloroplastic"
					},
					{
						"name":"105035408 DNA repair RAD52-like protein 2, chloroplastic\tK26558 RAD52-2; DNA repair RAD52-like protein 2, chloroplastic"
					}
					]
				},
				{
					"name":"Rad54 family proteins",
					"children":[
					{
						"name":"105042242 LOW QUALITY PROTEIN: protein CHROMATIN REMODELING 35\tK10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]"
					},
					{
						"name":"105043888 SNF2 domain-containing protein CLASSY 4-like\tK10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]"
					},
					{
						"name":"105053240 protein CHROMATIN REMODELING 35\tK10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]"
					},
					{
						"name":"105057160 SNF2 domain-containing protein CLASSY 2\tK10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]"
					},
					{
						"name":"105060877 LOW QUALITY PROTEIN: DNA repair and recombination protein RAD54\tK10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]"
					},
					{
						"name":"140857144 LOW QUALITY PROTEIN: SNF2 domain-containing protein CLASSY 4-like\tK10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]"
					}
					]
				},
				{
					"name":"RecQ family DNA helicases",
					"children":[
					{
						"name":"105039907 ATP-dependent DNA helicase Q-like 1\tK10899 RECQL; ATP-dependent DNA helicase Q1 [EC:5.6.2.4]"
					},
					{
						"name":"105060817 ATP-dependent DNA helicase Q-like 2 isoform X6\tK10899 RECQL; ATP-dependent DNA helicase Q1 [EC:5.6.2.4]"
					},
					{
						"name":"105032154 ATP-dependent DNA helicase Q-like SIM isoform X2\tK10900 WRN; werner syndrome ATP-dependent helicase [EC:5.6.2.4]"
					},
					{
						"name":"105042050 ATP-dependent DNA helicase Q-like 3\tK10901 BLM; bloom syndrome protein [EC:5.6.2.4]"
					},
					{
						"name":"105051907 LOW QUALITY PROTEIN: ATP-dependent DNA helicase Q-like 4A\tK10901 BLM; bloom syndrome protein [EC:5.6.2.4]"
					},
					{
						"name":"105038715 LOW QUALITY PROTEIN: ATP-dependent DNA helicase Q-like 5\tK10730 RECQL4; ATP-dependent DNA helicase Q4 [EC:5.6.2.4]"
					}
					]
				},
				{
					"name":"Bloom's syndrome complex (BTR)",
					"children":[
					{
						"name":"105042050 ATP-dependent DNA helicase Q-like 3\tK10901 BLM; bloom syndrome protein [EC:5.6.2.4]"
					},
					{
						"name":"105051907 LOW QUALITY PROTEIN: ATP-dependent DNA helicase Q-like 4A\tK10901 BLM; bloom syndrome protein [EC:5.6.2.4]"
					},
					{
						"name":"105034089 DNA topoisomerase 3-alpha isoform X1\tK03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]"
					},
					{
						"name":"105048885 DNA topoisomerase 3-beta isoform X1\tK03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]"
					},
					{
						"name":"105051117 recQ-mediated genome instability protein 1\tK10990 RMI1; RecQ-mediated genome instability protein 1"
					},
					{
						"name":"105053856 uncharacterized protein\tK15365 RMI2; RecQ-mediated genome instability protein 2"
					}
					]
				},
				{
					"name":"RPA (replication factor A)",
					"children":[
					{
						"name":"105044402 replication protein A 70 kDa DNA-binding subunit A\tK07466 RFA1; replication factor A1"
					},
					{
						"name":"105056091 LOW QUALITY PROTEIN: replication protein A 70 kDa DNA-binding subunit B\tK07466 RFA1; replication factor A1"
					},
					{
						"name":"109505580 replication protein A 70 kDa DNA-binding subunit A\tK07466 RFA1; replication factor A1"
					},
					{
						"name":"105035014 replication protein A 32 kDa subunit A\tK10739 RFA2; replication factor A2"
					},
					{
						"name":"105050800 replication protein A 32 kDa subunit B isoform X1\tK10739 RFA2; replication factor A2"
					},
					{
						"name":"105055410 replication protein A 32 kDa subunit A isoform X1\tK10739 RFA2; replication factor A2"
					},
					{
						"name":"105039914 replication protein A 14 kDa subunit\tK10740 RPA3; replication factor A3"
					},
					{
						"name":"105052578 replication protein A 14 kDa subunit\tK10740 RPA3; replication factor A3"
					}
					]
				},
				{
					"name":"Protein phosphatase 4",
					"children":[
					{
						"name":"105039499 serine\/threonine-protein phosphatase PP-X isozyme 2\tK15423 PPP4C; serine\/threonine-protein phosphatase 4 catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"105050520 serine\/threonine-protein phosphatase PP-X isozyme 2\tK15423 PPP4C; serine\/threonine-protein phosphatase 4 catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"105042241 uncharacterized protein isoform X3\tK15425 PPP4R2; serine\/threonine-protein phosphatase 4 regulatory subunit 2"
					},
					{
						"name":"105039929 uncharacterized protein isoform X4\tK17491 SMEK; protein phosphatase 4 regulatory subunit 3"
					},
					{
						"name":"105052597 uncharacterized protein isoform X2\tK17491 SMEK; protein phosphatase 4 regulatory subunit 3"
					}
					]
				},
				{
					"name":"AP-5 complex",
					"children":[
					{
						"name":"105055407 uncharacterized protein\tK19022 AP5B1; AP-5 complex subunit beta-1"
					},
					{
						"name":"105052711 AP-5 complex subunit mu isoform X2\tK19023 AP5M1; AP-5 complex subunit mu-1"
					},
					{
						"name":"105034796 uncharacterized protein isoform X2\tK19025 AP5Z1; AP-5 complex subunit zeta-1"
					}
					]
				},
				{
					"name":"SMC5-SMC6 complex",
					"children":[
					{
						"name":"105045561 structural maintenance of chromosomes protein 5\tK22803 SMC5; structural maintenance of chromosomes protein 5"
					},
					{
						"name":"105043644 structural maintenance of chromosomes protein 6B\tK22804 SMC6; structural maintenance of chromosomes protein 6"
					},
					{
						"name":"105046134 uncharacterized protein\tK22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27]"
					},
					{
						"name":"105043398 E3 SUMO-protein ligase MMS21\tK22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]"
					},
					{
						"name":"105050203 non-structural maintenance of chromosomes element 4 homolog A\tK22825 NSMCE4; non-structural maintenance of chromosomes element 4"
					},
					{
						"name":"105050480 LOW QUALITY PROTEIN: non-structural maintenance of chromosomes element 4 homolog A\tK22825 NSMCE4; non-structural maintenance of chromosomes element 4"
					},
					{
						"name":"105061232 non-structural maintenance of chromosomes element 4 homolog A isoform X1\tK22825 NSMCE4; non-structural maintenance of chromosomes element 4"
					}
					]
				},
				{
					"name":"Other HR factors",
					"children":[
					{
						"name":"105052818 crossover junction endonuclease EME1 isoform X1\tK10882 EME1; crossover junction endonuclease EME1 [EC:3.1.22.-]"
					},
					{
						"name":"105045367 crossover junction endonuclease MUS81 isoform X1\tK08991 MUS81; crossover junction endonuclease MUS81 [EC:3.1.22.-]"
					},
					{
						"name":"105057651 protein DELETION OF SUV3 SUPPRESSOR 1(I)\tK10881 SHFM1; 26 proteasome complex subunit DSS1"
					},
					{
						"name":"105057914 protein DELETION OF SUV3 SUPPRESSOR 1(I)\tK10881 SHFM1; 26 proteasome complex subunit DSS1"
					},
					{
						"name":"105045575 uncharacterized protein isoform X1\tK15078 SLX1; structure-specific endonuclease subunit SLX1 [EC:3.6.1.-]"
					},
					{
						"name":"105045952 uncharacterized protein\tK15078 SLX1; structure-specific endonuclease subunit SLX1 [EC:3.6.1.-]"
					},
					{
						"name":"105054587 flap endonuclease GEN-like 1\tK15338 GEN1; holliday junction resolvase GEN1\/YEN1 [EC:3.1.-.-]"
					},
					{
						"name":"105059017 single-strand DNA endonuclease 1 isoform X1\tK15338 GEN1; holliday junction resolvase GEN1\/YEN1 [EC:3.1.-.-]"
					},
					{
						"name":"105047910 uncharacterized protein\tK19026 SPG11; spatacsin"
					},
					{
						"name":"105047733 uncharacterized protein\tK19027 ZFYVE26; zinc finger FYVE domain-containing protein 26"
					},
					{
						"name":"105050172 protein MRG1\tK11339 MORF4L1; mortality factor 4-like protein 1"
					},
					{
						"name":"105061003 protein MRG1 isoform X1\tK11339 MORF4L1; mortality factor 4-like protein 1"
					},
					{
						"name":"105056301 uncharacterized protein\tK22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-]"
					},
					{
						"name":"105056148 uncharacterized protein isoform X1\tK25770 ZSWIM7; zinc finger SWIM domain-containing protein 7"
					},
					{
						"name":"105037910 LOW QUALITY PROTEIN: uncharacterized protein\tK27803 HROB; homologous recombination OB-fold protein"
					},
					{
						"name":"105035396 probable DNA helicase MCM8 isoform X2\tK10737 MCM8; DNA helicase MCM8 [EC:5.6.2.4]"
					},
					{
						"name":"105060545 LOW QUALITY PROTEIN: probable DNA helicase MCM9\tK10738 MCM9; DNA helicase MCM9 [EC:5.6.2.4]"
					},
					{
						"name":"105045432 uncharacterized protein\tK15047 HNRNPUL1; heterogeneous nuclear ribonucleoprotein U-like protein 1"
					},
					{
						"name":"105051257 uncharacterized protein\tK28623 MRNIP; MRN complex-interacting protein"
					},
					{
						"name":"105043148 3'-5' exonuclease isoform X1\tK22807 WRNexo; werner syndrome-like exonuclease [EC:3.1.11.-]"
					},
					{
						"name":"105039603 DNA-dependent metalloprotease WSS1\tK22685 WSS1; DNA-dependent metalloprotease WSS1 [EC:3.4.24.-]"
					},
					{
						"name":"105040360 single-stranded DNA-binding protein WHY1, chloroplastic isoform X3\tK26559 WHY1; single-stranded DNA-binding protein WHY1"
					},
					{
						"name":"105038531 single-stranded DNA-binding protein WHY2, mitochondrial\tK26561 WHY2; single-stranded DNA-binding protein WHY2"
					},
					{
						"name":"105049764 single-stranded DNA-binding protein WHY2, mitochondrial\tK26561 WHY2; single-stranded DNA-binding protein WHY2"
					}
					]
				}
				]
			},
			{
				"name":"NHEJ (non-homologous end-joining)",
				"children":[
				{
					"name":"DNA-PK complex",
					"children":[
					{
						"name":"105046549 ATP-dependent DNA helicase 2 subunit KU70\tK10884 XRCC6; ATP-dependent DNA helicase 2 subunit 1"
					},
					{
						"name":"105054786 ATP-dependent DNA helicase 2 subunit KU80 isoform X2\tK10885 XRCC5; ATP-dependent DNA helicase 2 subunit 2"
					}
					]
				},
				{
					"name":"MRX complex",
					"children":[
					{
						"name":"105033323 double-strand break repair protein MRE11 isoform X1\tK10865 MRE11; double-strand break repair protein MRE11"
					},
					{
						"name":"105052694 double-strand break repair protein MRE11 isoform X1\tK10865 MRE11; double-strand break repair protein MRE11"
					},
					{
						"name":"140858165 double-strand break repair protein MRE11-like\tK10865 MRE11; double-strand break repair protein MRE11"
					},
					{
						"name":"105049145 DNA repair protein RAD50 isoform X1\tK10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]"
					}
					]
				},
				{
					"name":"DNA Ligase 4 complex",
					"children":[
					{
						"name":"105039319 DNA ligase 4 isoform X1\tK10777 LIG4; DNA ligase 4 [EC:6.5.1.1]"
					},
					{
						"name":"140852490 LOW QUALITY PROTEIN: DNA ligase 4-like\tK10777 LIG4; DNA ligase 4 [EC:6.5.1.1]"
					},
					{
						"name":"105053440 DNA repair protein XRCC4\tK10886 XRCC4; DNA-repair protein XRCC4"
					}
					]
				},
				{
					"name":"X-family DNA polymerases",
					"children":[
					{
						"name":"105039164 DNA polymerase lambda isoform X1\tK03512 POLL; DNA polymerase lambda [EC:2.7.7.7 4.2.99.-]"
					}
					]
				},
				{
					"name":"Other NHEJ factors",
					"children":[
					{
						"name":"105057122 transcription factor bHLH140 isoform X1\tK10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]"
					},
					{
						"name":"105050978 uncharacterized protein isoform X1\tK19619 TDP2; tyrosyl-DNA phosphodiesterase 2 [EC:3.1.4.-]"
					},
					{
						"name":"105050993 uncharacterized protein isoform X1\tK19619 TDP2; tyrosyl-DNA phosphodiesterase 2 [EC:3.1.4.-]"
					},
					{
						"name":"105060094 uncharacterized protein isoform X1\tK19619 TDP2; tyrosyl-DNA phosphodiesterase 2 [EC:3.1.4.-]"
					},
					{
						"name":"105060143 uncharacterized protein\tK19619 TDP2; tyrosyl-DNA phosphodiesterase 2 [EC:3.1.4.-]"
					},
					{
						"name":"105040910 structural maintenance of chromosomes flexible hinge domain-containing protein GMI1\tK23113 SMCHD1; structural maintenance of chromosomes flexible hinge domain-containing protein 1"
					}
					]
				}
				]
			},
			{
				"name":"FA (Fanconi anemia) pathway",
				"children":[
				{
					"name":"FA core complex",
					"children":[
					{
						"name":"105058180 uncharacterized protein isoform X1\tK10606 FANCL; E3 ubiquitin-protein ligase FANCL [EC:2.3.2.27]"
					},
					{
						"name":"105051846 DEAD-box ATP-dependent RNA helicase FANCM isoform X1\tK10896 FANCM; fanconi anemia group M protein"
					}
					]
				},
				{
					"name":"FA core complex binding factors",
					"children":[
					{
						"name":"105051092 protein MHF1 homolog isoform X2\tK11511 APITD1; centromere protein S"
					},
					{
						"name":"105061584 protein MHF2 homolog isoform X1\tK15360 STRA13; centromere protein X"
					},
					{
						"name":"140851735 protein MHF2 homolog isoform X1\tK15360 STRA13; centromere protein X"
					},
					{
						"name":"105047102 uncharacterized protein isoform X1\tK13960 UBE2T; ubiquitin-conjugating enzyme E2 T [EC:2.3.2.23]"
					}
					]
				},
				{
					"name":"Bloom's syndrome complex (BTR)",
					"children":[
					{
						"name":"105042050 ATP-dependent DNA helicase Q-like 3\tK10901 BLM; bloom syndrome protein [EC:5.6.2.4]"
					},
					{
						"name":"105051907 LOW QUALITY PROTEIN: ATP-dependent DNA helicase Q-like 4A\tK10901 BLM; bloom syndrome protein [EC:5.6.2.4]"
					},
					{
						"name":"105034089 DNA topoisomerase 3-alpha isoform X1\tK03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]"
					},
					{
						"name":"105048885 DNA topoisomerase 3-beta isoform X1\tK03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]"
					},
					{
						"name":"105051117 recQ-mediated genome instability protein 1\tK10990 RMI1; RecQ-mediated genome instability protein 1"
					},
					{
						"name":"105053856 uncharacterized protein\tK15365 RMI2; RecQ-mediated genome instability protein 2"
					}
					]
				},
				{
					"name":"FANCD2-I complex",
					"children":[
					{
						"name":"105060277 uncharacterized protein isoform X1\tK10891 FANCD2; fanconi anemia group D2 protein"
					},
					{
						"name":"105045158 LOW QUALITY PROTEIN: uncharacterized protein\tK10895 FANCI; fanconi anemia group I protein"
					}
					]
				},
				{
					"name":"Downstream FA components",
					"children":[
					{
						"name":"105057159 protein BREAST CANCER SUSCEPTIBILITY 2 homolog B isoform X1\tK08775 BRCA2; breast cancer 2 susceptibility protein"
					},
					{
						"name":"105055234 uncharacterized protein isoform X2\tK15362 BRIP1; fanconi anemia group J protein [EC:5.6.2.3]"
					}
					]
				},
				{
					"name":"Other FA pathway factors",
					"children":[
					{
						"name":"105051220 LOW QUALITY PROTEIN: fanconi-associated nuclease 1 homolog\tK15363 FAN1; fanconi-associated nuclease 1 [EC:3.1.21.- 3.1.4.1]"
					},
					{
						"name":"105056665 DNA repair protein RAD51 homolog\tK04482 RAD51; DNA repair protein RAD51"
					},
					{
						"name":"105058584 LOW QUALITY PROTEIN: DNA repair protein RAD51 homolog\tK04482 RAD51; DNA repair protein RAD51"
					},
					{
						"name":"105059023 DNA repair protein RAD51 homolog 3 isoform X1\tK10870 RAD51L2; RAD51-like protein 2"
					},
					{
						"name":"105038727 LOW QUALITY PROTEIN: uncharacterized protein\tK11137 TELO2; telomere length regulation protein"
					},
					{
						"name":"105032370 uncharacterized protein isoform X1\tK15361 WDR48; WD repeat-containing protein 48"
					},
					{
						"name":"105035370 uncharacterized protein isoform X1\tK15361 WDR48; WD repeat-containing protein 48"
					}
					]
				}
				]
			},
			{
				"name":"Other DSBR factors",
				"children":[
				{
					"name":"Protein phosphatase 6",
					"children":[
					{
						"name":"105045744 phytochrome-associated serine\/threonine-protein phosphatase\tK15498 PPP6C; serine\/threonine-protein phosphatase 6 catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"105055470 phytochrome-associated serine\/threonine-protein phosphatase\tK15498 PPP6C; serine\/threonine-protein phosphatase 6 catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"105058981 LOW QUALITY PROTEIN: phytochrome-associated serine\/threonine-protein phosphatase\tK15498 PPP6C; serine\/threonine-protein phosphatase 6 catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"105049096 uncharacterized protein\tK15501 PPP6R3; serine\/threonine-protein phosphatase 6 regulatory subunit 3"
					},
					{
						"name":"105059799 uncharacterized protein isoform X1\tK15501 PPP6R3; serine\/threonine-protein phosphatase 6 regulatory subunit 3"
					}
					]
				},
				{
					"name":"Ubiquitin ligases"
				},
				{
					"name":"Others",
					"children":[
					{
						"name":"105034837 uncharacterized protein isoform X1\tK23314 WRAP53; telomerase Cajal body protein 1"
					},
					{
						"name":"105043188 LOW QUALITY PROTEIN: uncharacterized protein\tK24752 WDR70; WD repeat-containing protein 70"
					},
					{
						"name":"105053662 uncharacterized protein isoform X1\tK24752 WDR70; WD repeat-containing protein 70"
					},
					{
						"name":"105052942 uncharacterized protein\tK24755 WDR76; WD repeat-containing protein 76"
					},
					{
						"name":"105035553 uncharacterized protein isoform X1\tK28434 HMCES; abasic site processing protein HMCES"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"TLS (translesion DNA synthesis) factors",
			"children":[
			{
				"name":"Y-family DNA polymerases",
				"children":[
				{
					"name":"105035291 DNA polymerase eta isoform X1\tK03509 POLH; DNA polymerase eta [EC:2.7.7.7]"
				},
				{
					"name":"105032776 DNA polymerase kappa isoform X1\tK03511 POLK; DNA polymerase kappa [EC:2.7.7.7]"
				},
				{
					"name":"105053298 DNA repair protein REV1 isoform X1\tK03515 REV1; DNA repair protein REV1 [EC:2.7.7.-]"
				}
				]
			},
			{
				"name":"B-family DNA polymerases",
				"children":[
				{
					"name":"105045240 DNA polymerase zeta catalytic subunit isoform X1\tK02350 REV3L; DNA polymerase zeta [EC:2.7.7.7]"
				}
				]
			},
			{
				"name":"A-family DNA polymerase"
			},
			{
				"name":"Rad6 epistasis group",
				"children":[
				{
					"name":"105040310 ubiquitin-conjugating enzyme E2 2 isoform X1\tK10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]"
				},
				{
					"name":"105044960 ubiquitin-conjugating enzyme E2 2\tK10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]"
				},
				{
					"name":"105047918 ubiquitin-conjugating enzyme E2 2\tK10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]"
				},
				{
					"name":"105051334 ubiquitin-conjugating enzyme E2 2 isoform X2\tK10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]"
				},
				{
					"name":"105053254 ubiquitin-conjugating enzyme E2 2\tK10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]"
				},
				{
					"name":"105055896 ubiquitin-conjugating enzyme E2 2\tK10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]"
				},
				{
					"name":"140850946 ubiquitin-conjugating enzyme E2 2-like\tK10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]"
				},
				{
					"name":"105038192 DNA repair protein RAD5A isoform X1\tK15505 RAD5; DNA repair protein RAD5 [EC:5.6.2.-]"
				},
				{
					"name":"105043103 LOW QUALITY PROTEIN: DNA repair protein RAD5B\tK15505 RAD5; DNA repair protein RAD5 [EC:5.6.2.-]"
				},
				{
					"name":"105035256 putative SWI\/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3-like 1\tK15711 SMARCA3; SWI\/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A3 [EC:5.6.2. 2.3.2.27]"
				},
				{
					"name":"105033958 ubiquitin-conjugating enzyme E2 variant 1C\tK10704 UBE2V; ubiquitin-conjugating enzyme E2 variant"
				},
				{
					"name":"105037858 ubiquitin-conjugating enzyme E2 variant 1D\tK10704 UBE2V; ubiquitin-conjugating enzyme E2 variant"
				},
				{
					"name":"105038291 ubiquitin-conjugating enzyme E2 variant 1D\tK10704 UBE2V; ubiquitin-conjugating enzyme E2 variant"
				},
				{
					"name":"105041098 ubiquitin-conjugating enzyme E2 variant 1D\tK10704 UBE2V; ubiquitin-conjugating enzyme E2 variant"
				},
				{
					"name":"105048496 ubiquitin-conjugating enzyme E2 variant 1D\tK10704 UBE2V; ubiquitin-conjugating enzyme E2 variant"
				},
				{
					"name":"105054259 ubiquitin-conjugating enzyme E2 variant 1D\tK10704 UBE2V; ubiquitin-conjugating enzyme E2 variant"
				},
				{
					"name":"105054664 ubiquitin-conjugating enzyme E2 variant 1C\tK10704 UBE2V; ubiquitin-conjugating enzyme E2 variant"
				},
				{
					"name":"140852516 ubiquitin-conjugating enzyme E2 variant 1D-like\tK10704 UBE2V; ubiquitin-conjugating enzyme E2 variant"
				},
				{
					"name":"105043931 ubiquitin-conjugating enzyme E2 36 isoform X1\tK10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]"
				},
				{
					"name":"105047395 ubiquitin-conjugating enzyme E2 36 isoform X1\tK10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]"
				}
				]
			},
			{
				"name":"Other TLS factors",
				"children":[
				{
					"name":"105046296 proliferating cell nuclear antigen\tK04802 PCNA; proliferating cell nuclear antigen"
				},
				{
					"name":"105050563 proliferating cell nuclear antigen\tK04802 PCNA; proliferating cell nuclear antigen"
				},
				{
					"name":"105054821 proliferating cell nuclear antigen isoform X2\tK04802 PCNA; proliferating cell nuclear antigen"
				}
				]
			}
			]
		},
		{
			"name":"Check point factors",
			"children":[
			{
				"name":"Rad9-Hus1-Rad1 complex",
				"children":[
				{
					"name":"105057491 LOW QUALITY PROTEIN: uncharacterized protein\tK10994 RAD9A; cell cycle checkpoint control protein RAD9A [EC:3.1.11.2]"
				},
				{
					"name":"105042828 uncharacterized protein isoform X1\tK10903 HUS1; HUS1 checkpoint protein"
				},
				{
					"name":"140857344 LOW QUALITY PROTEIN: uncharacterized protein\tK10903 HUS1; HUS1 checkpoint protein"
				},
				{
					"name":"105059370 uncharacterized protein isoform X1\tK02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]"
				}
				]
			},
			{
				"name":"HRAD17(Rad24)-RFC complex",
				"children":[
				{
					"name":"105053759 cell cycle checkpoint protein RAD17 isoform X3\tK06662 HRAD17; cell cycle checkpoint protein"
				},
				{
					"name":"105037415 replication factor C subunit 4\tK10755 RFC2_4; replication factor C subunit 2\/4"
				},
				{
					"name":"105051821 replication factor C subunit 2\tK10755 RFC2_4; replication factor C subunit 2\/4"
				},
				{
					"name":"140851747 replication factor C subunit 2\tK10755 RFC2_4; replication factor C subunit 2\/4"
				},
				{
					"name":"105036598 replication factor C subunit 3\tK10756 RFC3_5; replication factor C subunit 3\/5"
				},
				{
					"name":"105037514 replication factor C subunit 3\tK10756 RFC3_5; replication factor C subunit 3\/5"
				},
				{
					"name":"105053122 replication factor C subunit 3\tK10756 RFC3_5; replication factor C subunit 3\/5"
				},
				{
					"name":"140852096 replication factor C subunit 3\tK10756 RFC3_5; replication factor C subunit 3\/5"
				}
				]
			},
			{
				"name":"Rad17-Mec3-Ddc1 complex",
				"children":[
				{
					"name":"105059370 uncharacterized protein isoform X1\tK02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]"
				}
				]
			},
			{
				"name":"FPC (fork protection complex)",
				"children":[
				{
					"name":"105041822 uncharacterized protein isoform X1\tK10997 TIMELESS; replication fork protection complex subunit TIMELESS\/Tof1\/Swi1"
				},
				{
					"name":"105055374 uncharacterized protein\tK10998 TIPIN; replication fork protection complex subunit TIPIN\/Csm3\/Swi3"
				}
				]
			},
			{
				"name":"Triple T complex",
				"children":[
				{
					"name":"105038727 LOW QUALITY PROTEIN: uncharacterized protein\tK11137 TELO2; telomere length regulation protein"
				},
				{
					"name":"105053825 uncharacterized protein isoform X1\tK20403 TTI1; TELO2-interacting protein 1"
				},
				{
					"name":"105039656 uncharacterized protein At2g39910 isoform X1\tK23115 TTI2; TELO2-interacting protein 2"
				}
				]
			},
			{
				"name":"BAG6-UBL4A-GET4 complex",
				"children":[
				{
					"name":"105057157 protein GET4\tK23387 GET4; golgi to ER traffic protein 4"
				}
				]
			},
			{
				"name":"SOSS complex",
				"children":[
				{
					"name":"105058051 uncharacterized protein\tK13140 INTS3; integrator complex subunit 3 (SOSS complex subunit A)"
				},
				{
					"name":"105039796 uncharacterized protein isoform X3\tK28889 NABP; SOSS complex subunit B"
				}
				]
			},
			{
				"name":"Other check point factors",
				"children":[
				{
					"name":"105059675 serine\/threonine-protein kinase ATR isoform X1\tK06640 ATR; serine\/threonine-protein kinase ATR [EC:2.7.11.1]"
				},
				{
					"name":"105056273 serine\/threonine-protein kinase ATM isoform X1\tK04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]"
				},
				{
					"name":"105035799 14-3-3-like protein 16R\tK06630 YWHAE; 14-3-3 protein epsilon"
				},
				{
					"name":"105035815 LOW QUALITY PROTEIN: 14-3-3 protein 6\tK06630 YWHAE; 14-3-3 protein epsilon"
				},
				{
					"name":"105035816 14-3-3-like protein 16R\tK06630 YWHAE; 14-3-3 protein epsilon"
				},
				{
					"name":"105037590 14-3-3-like protein 16R\tK06630 YWHAE; 14-3-3 protein epsilon"
				},
				{
					"name":"105037838 14-3-3-like protein 16R isoform X1\tK06630 YWHAE; 14-3-3 protein epsilon"
				},
				{
					"name":"105040620 14-3-3-like protein D isoform X1\tK06630 YWHAE; 14-3-3 protein epsilon"
				},
				{
					"name":"105041071 14-3-3-like protein\tK06630 YWHAE; 14-3-3 protein epsilon"
				},
				{
					"name":"105041440 14-3-3-like protein 16R isoform X1\tK06630 YWHAE; 14-3-3 protein epsilon"
				},
				{
					"name":"105041595 14-3-3-like protein 16R\tK06630 YWHAE; 14-3-3 protein epsilon"
				},
				{
					"name":"105041596 14-3-3-like protein GF14 omega isoform X1\tK06630 YWHAE; 14-3-3 protein epsilon"
				},
				{
					"name":"105041602 14-3-3 protein 7 isoform X1\tK06630 YWHAE; 14-3-3 protein epsilon"
				},
				{
					"name":"105041928 14-3-3-like protein\tK06630 YWHAE; 14-3-3 protein epsilon"
				},
				{
					"name":"105043958 14-3-3-like protein D isoform X1\tK06630 YWHAE; 14-3-3 protein epsilon"
				},
				{
					"name":"105046648 14-3-3-like protein GF14 iota\tK06630 YWHAE; 14-3-3 protein epsilon"
				},
				{
					"name":"105047394 14-3-3-like protein D\tK06630 YWHAE; 14-3-3 protein epsilon"
				},
				{
					"name":"105048134 14-3-3 protein 9 isoform X1\tK06630 YWHAE; 14-3-3 protein epsilon"
				},
				{
					"name":"105048516 14-3-3-like protein\tK06630 YWHAE; 14-3-3 protein epsilon"
				},
				{
					"name":"105048640 LOW QUALITY PROTEIN: 14-3-3-like protein 16R\tK06630 YWHAE; 14-3-3 protein epsilon"
				},
				{
					"name":"105053212 14-3-3-like protein GF14-C\tK06630 YWHAE; 14-3-3 protein epsilon"
				},
				{
					"name":"105056773 LOW QUALITY PROTEIN: 14-3-3-like protein B\tK06630 YWHAE; 14-3-3 protein epsilon"
				},
				{
					"name":"105058213 14-3-3-like protein GF14 iota\tK06630 YWHAE; 14-3-3 protein epsilon"
				},
				{
					"name":"105058447 14-3-3 protein 6\tK06630 YWHAE; 14-3-3 protein epsilon"
				},
				{
					"name":"105058486 14-3-3-like protein G-BOX factor 14 lambda\tK06630 YWHAE; 14-3-3 protein epsilon"
				},
				{
					"name":"105060579 14-3-3-like protein G-BOX factor 14 kappa isoform X1\tK06630 YWHAE; 14-3-3 protein epsilon"
				},
				{
					"name":"140854124 14-3-3 protein 6-like\tK06630 YWHAE; 14-3-3 protein epsilon"
				},
				{
					"name":"105058695 LOW QUALITY PROTEIN: wee1-like protein kinase\tK06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]"
				},
				{
					"name":"105039817 uncharacterized protein isoform X1\tK20780 MDC1; mediator of DNA damage checkpoint protein 1"
				},
				{
					"name":"105038922 serine\/threonine-protein kinase Nek6 isoform X2\tK08857 NEK1_4_5; serine\/threonine-protein kinase Nek1\/4\/5 [EC:2.7.11.1]"
				},
				{
					"name":"105046594 serine\/threonine-protein kinase Nek2\tK08857 NEK1_4_5; serine\/threonine-protein kinase Nek1\/4\/5 [EC:2.7.11.1]"
				},
				{
					"name":"105057452 serine\/threonine-protein kinase Nek2\tK08857 NEK1_4_5; serine\/threonine-protein kinase Nek1\/4\/5 [EC:2.7.11.1]"
				},
				{
					"name":"105060423 serine\/threonine-protein kinase Nek5\tK08857 NEK1_4_5; serine\/threonine-protein kinase Nek1\/4\/5 [EC:2.7.11.1]"
				},
				{
					"name":"105034640 uncharacterized protein isoform X1\tK22422 DONSON; protein downstream neighbor of Son"
				},
				{
					"name":"105041283 protein SUPPRESSOR OF K(+) TRANSPORT GROWTH DEFECT 1\tK12196 VPS4; vacuolar protein-sorting-associated protein 4"
				},
				{
					"name":"105048751 protein SUPPRESSOR OF K(+) TRANSPORT GROWTH DEFECT 1\tK12196 VPS4; vacuolar protein-sorting-associated protein 4"
				},
				{
					"name":"105039199 uncharacterized protein\tK25059 SDE2; replication stress response regulator SDE2"
				},
				{
					"name":"105057577 protein DECREASED SIZE EXCLUSION LIMIT 1 isoform X2\tK24770 DSE1; protein decreased size exclusion limit 1"
				}
				]
			}
			]
		},
		{
			"name":"Other factors with a suspected DNA repair function",
			"children":[
			{
				"name":"DNA polymerases",
				"children":[
				{
					"name":"105040799 helicase and polymerase-containing protein TEBICHI isoform X2\tK02349 POLQ; DNA polymerase theta [EC:2.7.7.7]"
				},
				{
					"name":"105041174 uncharacterized protein\tK02331 POL5; DNA polymerase phi [EC:2.7.7.7]"
				},
				{
					"name":"140859039 LOW QUALITY PROTEIN: rDNA transcriptional regulator pol5-like\tK02331 POL5; DNA polymerase phi [EC:2.7.7.7]"
				},
				{
					"name":"105043322 uncharacterized protein isoform X1\tK22761 PRIMPOL; DNA-directed primase\/polymerase protein [EC:2.7.7.102 2.7.7.7]"
				}
				]
			},
			{
				"name":"Nucleases",
				"children":[
				{
					"name":"105037645 uncharacterized protein\tK15340 DCLRE1A; DNA cross-link repair 1A protein"
				},
				{
					"name":"105042070 uncharacterized protein\tK15340 DCLRE1A; DNA cross-link repair 1A protein"
				},
				{
					"name":"105051004 DNA cross-link repair protein SNM1\tK15340 DCLRE1A; DNA cross-link repair 1A protein"
				},
				{
					"name":"105053712 uncharacterized protein\tK15341 DCLRE1B; DNA cross-link repair 1B protein [EC:3.1.-.-]"
				},
				{
					"name":"105057061 exonuclease V, chloroplastic isoform X2\tK17815 EXO5; exonuclease V [EC:3.1.-.-]"
				},
				{
					"name":"105050430 uncharacterized protein isoform X1\tK21813 ENDOV; endonuclease V [EC:3.1.26.-]"
				},
				{
					"name":"105055998 LOW QUALITY PROTEIN: uncharacterized protein\tK25861 ZRANB3; DNA annealing helicase and endonuclease ZRANB3 [EC:5.6.2.- 3.1.-.-]"
				},
				{
					"name":"105041223 endonuclease 4\tK05986 NUCS; nuclease S1 [EC:3.1.30.1]"
				},
				{
					"name":"105041224 endonuclease 2\tK05986 NUCS; nuclease S1 [EC:3.1.30.1]"
				},
				{
					"name":"105041226 endonuclease 2\tK05986 NUCS; nuclease S1 [EC:3.1.30.1]"
				},
				{
					"name":"105041227 endonuclease 2-like\tK05986 NUCS; nuclease S1 [EC:3.1.30.1]"
				},
				{
					"name":"105045414 endonuclease 1\tK05986 NUCS; nuclease S1 [EC:3.1.30.1]"
				}
				]
			},
			{
				"name":"Helicases",
				"children":[
				{
					"name":"105050614 switch 2\tK20098 ERCC6L2; DNA excision repair protein ERCC-6-like 2 [EC:5.6.2.-]"
				}
				]
			},
			{
				"name":"PSO4 complex",
				"children":[
				{
					"name":"105044183 pre-mRNA-processing factor 19\tK10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]"
				},
				{
					"name":"105054436 pre-mRNA-processing factor 19 isoform X1\tK10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]"
				},
				{
					"name":"105039969 cell division cycle 5-like protein\tK12860 CDC5L; pre-mRNA-splicing factor CDC5\/CEF1"
				},
				{
					"name":"105039972 cell division cycle 5-like protein\tK12860 CDC5L; pre-mRNA-splicing factor CDC5\/CEF1"
				},
				{
					"name":"105061343 pre-mRNA-splicing factor SPF27 homolog\tK12861 BCAS2; pre-mRNA-splicing factor SPF27"
				},
				{
					"name":"105045188 protein pleiotropic regulatory locus 1\tK12862 PLRG1; pleiotropic regulator 1"
				}
				]
			},
			{
				"name":"Modulation of nucleotide pools",
				"children":[
				{
					"name":"105036047 deoxyuridine 5'-triphosphate nucleotidohydrolase-like\tK01520 dut; dUTP diphosphatase [EC:3.6.1.23]"
				},
				{
					"name":"105055060 deoxyuridine 5'-triphosphate nucleotidohydrolase\tK01520 dut; dUTP diphosphatase [EC:3.6.1.23]"
				},
				{
					"name":"105038036 ribonucleoside-diphosphate reductase large subunit\tK10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]"
				},
				{
					"name":"105041246 ribonucleoside-diphosphate reductase large subunit\tK10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]"
				},
				{
					"name":"105048410 ribonucleoside-diphosphate reductase large subunit isoform X1\tK10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]"
				},
				{
					"name":"105032431 ribonucleoside-diphosphate reductase small chain\tK10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]"
				},
				{
					"name":"105042120 ribonucleoside-diphosphate reductase small chain\tK10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic type",
		"children":[
		{
			"name":"SSBR (single strand breaks repair)",
			"children":[
			{
				"name":"Direct repair",
				"children":[
				{
					"name":"105042716 deoxyribodipyrimidine photo-lyase isoform X2\tK01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]"
				}
				]
			},
			{
				"name":"BER (base exicision repair)",
				"children":[
				{
					"name":"DNA glycosylases",
					"children":[
					{
						"name":"105055388 uracil-DNA glycosylase, mitochondrial isoform X1\tK03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]"
					},
					{
						"name":"105058927 uracil-DNA glycosylase, mitochondrial\tK03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]"
					},
					{
						"name":"105047171 alkylbase DNA glycosidase-like protein mag2\tK01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]"
					},
					{
						"name":"105053127 DNA-3-methyladenine glycosylase isoform X1\tK03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]"
					},
					{
						"name":"140858208 DNA-3-methyladenine glycosylase-like isoform X1\tK03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]"
					},
					{
						"name":"105051527 adenine DNA glycosylase\tK03575 mutY; A\/G-specific adenine glycosylase [EC:3.2.2.31]"
					},
					{
						"name":"105034696 uncharacterized protein\tK01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]"
					},
					{
						"name":"105034716 uncharacterized protein\tK01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]"
					},
					{
						"name":"105050470 uncharacterized protein\tK01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]"
					},
					{
						"name":"105050731 uncharacterized protein\tK01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]"
					},
					{
						"name":"105060180 uncharacterized protein\tK01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]"
					},
					{
						"name":"105060960 uncharacterized protein\tK01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]"
					},
					{
						"name":"105061078 uncharacterized protein\tK01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]"
					},
					{
						"name":"105050126 formamidopyrimidine-DNA glycosylase isoform X1\tK10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]"
					},
					{
						"name":"105039152 uncharacterized protein isoform X1\tK10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]"
					},
					{
						"name":"105051450 endonuclease III homolog 1, chloroplastic\tK10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]"
					}
					]
				},
				{
					"name":"AP endonucleases",
					"children":[
					{
						"name":"105031940 DNA-(apurinic or apyrimidinic site) endonuclease, chloroplastic isoform X1\tK01142 xthA; exodeoxyribonuclease III [EC:3.1.11.2]"
					}
					]
				},
				{
					"name":"RecJ"
				},
				{
					"name":"DNA ligase"
				},
				{
					"name":"DNA polymerase I",
					"children":[
					{
						"name":"105033029 DNA polymerase I A, chloroplastic isoform X1\tK02335 polA; DNA polymerase I [EC:2.7.7.7]"
					}
					]
				}
				]
			},
			{
				"name":"NER (nucleotide excision repair)",
				"children":[
				{
					"name":"GGR (global genome repair) factors",
					"children":[
					{
						"name":"105033029 DNA polymerase I A, chloroplastic isoform X1\tK02335 polA; DNA polymerase I [EC:2.7.7.7]"
					}
					]
				},
				{
					"name":"TCR (transcription coupled repair) factors",
					"children":[
					{
						"name":"DNA-directed RNA polymerase complex (RNAP)",
						"children":[
						{
							"name":"12079461 rpoB; RNA polymerase beta subunit\tK03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]"
						},
						{
							"name":"12079459 rpoC2; RNA polymerase beta' subunit\tK03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]"
						},
						{
							"name":"12079460 rpoC1; RNA polymerase beta subunit\tK03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]"
						},
						{
							"name":"12079509 rpoA; RNA polymerase alpha subunit\tK03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]"
						}
						]
					},
					{
						"name":"TRCF (transcription-repair coupling factor)"
					}
					]
				}
				]
			},
			{
				"name":"MMR (mismatch excision repair)",
				"children":[
				{
					"name":"Mismatch and loop recognition factors",
					"children":[
					{
						"name":"105054914 LOW QUALITY PROTEIN: allantoinase\tK07456 mutS2; DNA mismatch repair protein MutS2"
					}
					]
				},
				{
					"name":"Molecular matchmaker"
				},
				{
					"name":"Strand discrimination factor"
				},
				{
					"name":"DNA exonucleases"
				},
				{
					"name":"DNA polymerase III holoenzyme"
				},
				{
					"name":"DNA ligase"
				},
				{
					"name":"Other MMR factors",
					"children":[
					{
						"name":"105047096 single-stranded DNA-binding protein, mitochondrial\tK03111 ssb; single-strand DNA-binding protein"
					},
					{
						"name":"105047680 single-stranded DNA-binding protein, mitochondrial\tK03111 ssb; single-strand DNA-binding protein"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"DSBR (double strand breaks repair)",
			"children":[
			{
				"name":"HR (homologous recombination)",
				"children":[
				{
					"name":"RecBC pathway proteins",
					"children":[
					{
						"name":"105032022 DNA repair protein recA homolog 1, chloroplastic isoform X1\tK03553 recA; recombination protein RecA"
					},
					{
						"name":"105035722 DNA repair protein recA homolog 3, mitochondrial isoform X1\tK03553 recA; recombination protein RecA"
					}
					]
				},
				{
					"name":"RecFOR pathway proteins",
					"children":[
					{
						"name":"105032022 DNA repair protein recA homolog 1, chloroplastic isoform X1\tK03553 recA; recombination protein RecA"
					},
					{
						"name":"105035722 DNA repair protein recA homolog 3, mitochondrial isoform X1\tK03553 recA; recombination protein RecA"
					},
					{
						"name":"105040500 uncharacterized protein\tK04485 radA; DNA repair protein RadA\/Sms"
					},
					{
						"name":"105056344 ATP-dependent DNA helicase homolog RECG1, chloroplastic\/mitochondrial\tK03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]"
					}
					]
				},
				{
					"name":"AddAB pathway proteins"
				},
				{
					"name":"Other HR factor"
				},
				{
					"name":"Archaeal homologous recombinant proteins"
				}
				]
			},
			{
				"name":"NHEJ (non-homologous end-joining)",
				"children":[
				{
					"name":"Two-component NHEJ DNA repair complex"
				},
				{
					"name":"SHIIR (short-homology-independent illegitimate recombination)",
					"children":[
					{
						"name":"Facilitator",
						"children":[
						{
							"name":"105046114 DNA gyrase subunit A, chloroplastic\/mitochondrial isoform X1\tK02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]"
						},
						{
							"name":"105053232 DNA gyrase subunit B, chloroplastic\/mitochondrial\tK02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]"
						}
						]
					},
					{
						"name":"Supressor"
					}
					]
				},
				{
					"name":"SHDIR (short-homology-dependent illegitimate recombination)",
					"children":[
					{
						"name":"RecET pathway"
					},
					{
						"name":"Facilitator"
					},
					{
						"name":"Supressor",
						"children":[
						{
							"name":"105045099 uncharacterized protein\tK03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]"
						}
						]
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"TLS (translesion DNA synthesis) factors",
			"children":[
			{
				"name":"Y-family DNA polymerases"
			},
			{
				"name":"Other SOS response factors",
				"children":[
				{
					"name":"105032022 DNA repair protein recA homolog 1, chloroplastic isoform X1\tK03553 recA; recombination protein RecA"
				},
				{
					"name":"105035722 DNA repair protein recA homolog 3, mitochondrial isoform X1\tK03553 recA; recombination protein RecA"
				},
				{
					"name":"105047096 single-stranded DNA-binding protein, mitochondrial\tK03111 ssb; single-strand DNA-binding protein"
				},
				{
					"name":"105047680 single-stranded DNA-binding protein, mitochondrial\tK03111 ssb; single-strand DNA-binding protein"
				}
				]
			}
			]
		},
		{
			"name":"Other factors with a suspected DNA repair function",
			"children":[
			{
				"name":"DNA polymerase"
			},
			{
				"name":"DNA helicases"
			},
			{
				"name":"Modulation of nucleotide pools",
				"children":[
				{
					"name":"105036047 deoxyuridine 5'-triphosphate nucleotidohydrolase-like\tK01520 dut; dUTP diphosphatase [EC:3.6.1.23]"
				},
				{
					"name":"105055060 deoxyuridine 5'-triphosphate nucleotidohydrolase\tK01520 dut; dUTP diphosphatase [EC:3.6.1.23]"
				}
				]
			},
			{
				"name":"Others"
			}
			]
		}
		]
	}
	]
}
