{
	"name":"ela03400",
	"children":[
	{
		"name":"Eukaryotic type",
		"children":[
		{
			"name":"SSBR (single strand breaks repair)",
			"children":[
			{
				"name":"Direct repair",
				"children":[
				{
					"name":"UCREL1_5984 putative ring-2 protein\tK00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]"
				},
				{
					"name":"UCREL1_1319 putative deoxyribodipyrimidine photo-lyase protein\tK01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]"
				}
				]
			},
			{
				"name":"BER (base exicision repair)",
				"children":[
				{
					"name":"DNA glycosylases",
					"children":[
					{
						"name":"UCREL1_3974 putative uracil-dna glycosylase protein\tK03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]"
					},
					{
						"name":"UCREL1_6459 putative g u mismatch-specific uracil dna glycosylase protein\tK20813 TDG; thymine-DNA glycosylase [EC:3.2.2.29]"
					},
					{
						"name":"UCREL1_5901 putative a g-specific adenine glycosylase protein\tK03575 mutY; A\/G-specific adenine glycosylase [EC:3.2.2.31]"
					},
					{
						"name":"UCREL1_7980 putative n-glycosylase dna lyase protein\tK03660 OGG1; N-glycosylase\/DNA lyase [EC:3.2.2.- 4.2.99.18]"
					},
					{
						"name":"UCREL1_9365 putative dna repair protein ntg1 protein\tK10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]"
					}
					]
				},
				{
					"name":"AP endonucleases",
					"children":[
					{
						"name":"UCREL1_7989 putative dna-(apurinic or apyrimidinic site) lyase 1 protein\tK10771 APEX1; AP endonuclease 1 [EC:3.1.11.2]"
					}
					]
				},
				{
					"name":"Long Patch-BER factors",
					"children":[
					{
						"name":"DNA polymerase delta complex",
						"children":[
						{
							"name":"UCREL1_220 putative dna polymerase delta catalytic subunit protein\tK02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]"
						},
						{
							"name":"UCREL1_370 putative dna polymerase delta small subunit protein\tK02328 POLD2; DNA polymerase delta subunit 2"
						},
						{
							"name":"UCREL1_4138 putative dna polymerase subunit cdc27 protein\tK03504 POLD3; DNA polymerase delta subunit 3"
						},
						{
							"name":"UCREL1_5998 putative dna polymerase delta protein\tK03505 POLD4; DNA polymerase delta subunit 4"
						}
						]
					},
					{
						"name":"DNA polymerase epsilon complex",
						"children":[
						{
							"name":"UCREL1_3210 putative dna polymerase epsilon protein\tK02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]"
						},
						{
							"name":"UCREL1_7576 putative dna polymerase epsilon subunit b protein\tK02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]"
						}
						]
					},
					{
						"name":"UCREL1_1256 putative proliferating cell nuclear antigen protein\tK04802 PCNA; proliferating cell nuclear antigen"
					},
					{
						"name":"UCREL1_5188 putative dna-repair protein rad2 protein\tK04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]"
					},
					{
						"name":"UCREL1_546 putative dna ligase protein\tK10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]"
					}
					]
				},
				{
					"name":"Short Patch-BER factors"
				},
				{
					"name":"Other BER factors",
					"children":[
					{
						"name":"UCREL1_10181 putative phospholipase d nuclease protein\tK10862 TDP1; tyrosyl-DNA phosphodiesterase 1 [EC:3.1.4.-]"
					},
					{
						"name":"UCREL1_3659 putative tyrosyl-dna phosphodiesterase protein\tK10862 TDP1; tyrosyl-DNA phosphodiesterase 1 [EC:3.1.4.-]"
					},
					{
						"name":"UCREL1_4929 putative aprataxin-like protein\tK10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]"
					},
					{
						"name":"UCREL1_568 putative poly polymerase 2 adp-ribosyltransferase 2 protein\tK28005 PARP2; poly [ADP-ribose] polymerase 2 [EC:2.4.2.30]"
					}
					]
				}
				]
			},
			{
				"name":"NER (nucleotide excision repair)",
				"children":[
				{
					"name":"GGR (global genome repair) factors",
					"children":[
					{
						"name":"XPC-HR23B-CETN2 complex",
						"children":[
						{
							"name":"UCREL1_10030 putative dna repair protein rhp41 protein\tK10838 XPC; xeroderma pigmentosum group C-complementing protein"
						},
						{
							"name":"UCREL1_11433 putative rad4 family protein\tK10838 XPC; xeroderma pigmentosum group C-complementing protein"
						},
						{
							"name":"UCREL1_10280 putative uv excision repair protein\tK10839 RAD23; UV excision repair protein RAD23"
						}
						]
					},
					{
						"name":"Cul4-DDB2 complex",
						"children":[
						{
							"name":"UCREL1_3121 putative ring-box protein 1 protein\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
						},
						{
							"name":"UCREL1_10848 putative ubiquitin ligase subunit protein\tK10609 CUL4; cullin 4"
						},
						{
							"name":"UCREL1_11438 putative uv-damaged dna-binding protein\tK10610 DDB1; DNA damage-binding protein 1"
						}
						]
					},
					{
						"name":"NER4 complex",
						"children":[
						{
							"name":"UCREL1_4006 putative dna repair protein\tK15082 RAD7; DNA repair protein RAD7"
						},
						{
							"name":"UCREL1_4005 putative dna repair protein rad16 protein\tK15083 RAD16; DNA repair protein RAD16"
						}
						]
					}
					]
				},
				{
					"name":"TCR (transcription coupled repair) factors",
					"children":[
					{
						"name":"DNA-directed RNA polymerase II complex",
						"children":[
						{
							"name":"UCREL1_1205 putative rna polymerase ii largest subunit protein\tK03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]"
						},
						{
							"name":"UCREL1_7799 putative dna-directed rna polymerase ii subunit rpb2 protein\tK03010 RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]"
						},
						{
							"name":"UCREL1_9891 putative rna polymerase rpb4 protein\tK03012 RPB4; DNA-directed RNA polymerase II subunit RPB4"
						},
						{
							"name":"UCREL1_8824 putative dna-directed rna polymerases ii 24 kda polypeptide protein\tK03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1"
						},
						{
							"name":"UCREL1_9247 putative dna-directed rna polymerases i protein\tK03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2"
						},
						{
							"name":"UCREL1_7499 hypothetical protein\tK03015 RPB7; DNA-directed RNA polymerase II subunit RPB7"
						},
						{
							"name":"UCREL1_1430 putative dna-directed rna polymerases i ii iii subunit 10 protein\tK03007 RPABC5; DNA-directed RNA polymerases I, II, and III subunit RPABC5"
						},
						{
							"name":"UCREL1_375 putative dna-directed rna polymerase ii subunit rpb11 protein\tK03008 RPB11; DNA-directed RNA polymerase II subunit RPB11"
						},
						{
							"name":"UCREL1_4451 putative metallothionein-i gene transcription activator protein\tK03009 RPABC4; DNA-directed RNA polymerases I, II, and III subunit RPABC4"
						}
						]
					},
					{
						"name":"Cul4-CSA complex",
						"children":[
						{
							"name":"UCREL1_3121 putative ring-box protein 1 protein\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
						},
						{
							"name":"UCREL1_10848 putative ubiquitin ligase subunit protein\tK10609 CUL4; cullin 4"
						},
						{
							"name":"UCREL1_11438 putative uv-damaged dna-binding protein\tK10610 DDB1; DNA damage-binding protein 1"
						},
						{
							"name":"UCREL1_7544 putative dna excision repair protein ercc-8 protein\tK10570 ERCC8; DNA excision repair protein ERCC-8"
						}
						]
					},
					{
						"name":"Other TCR factor",
						"children":[
						{
							"name":"UCREL1_11620 putative dna repair and recombination protein rad26 protein\tK10841 ERCC6; DNA excision repair protein ERCC-6"
						},
						{
							"name":"UCREL1_11145 putative transcription elongation protein\tK25829 ELOF1; transcription elongation factor 1"
						}
						]
					}
					]
				},
				{
					"name":"TFIIH complex",
					"children":[
					{
						"name":"UCREL1_1799 putative dna repair helicase rad25 protein\tK10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]"
					},
					{
						"name":"UCREL1_11571 putative dna repair helicase rad15 protein\tK10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]"
					},
					{
						"name":"UCREL1_931 putative tfiih p62 subunit domain-containing protein\tK03141 TFIIH1; transcription initiation factor TFIIH subunit 1"
					},
					{
						"name":"UCREL1_9807 putative tfiih basal transcription factor complex p47 subunit protein\tK03142 TFIIH2; transcription initiation factor TFIIH subunit 2"
					},
					{
						"name":"UCREL1_6123 putative rna polymerase ii transcription factor b subunit 4 protein\tK03143 TFIIH3; transcription initiation factor TFIIH subunit 3"
					},
					{
						"name":"UCREL1_10829 putative rna polymerase ii transcription factor b subunit 2 protein\tK03144 TFIIH4; transcription initiation factor TFIIH subunit 4"
					},
					{
						"name":"UCREL1_3159 putative serine threonine-protein kinase protein\tK02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]"
					},
					{
						"name":"UCREL1_4698 putative cyclin ccl1 protein\tK06634 CCNH; cyclin H"
					},
					{
						"name":"UCREL1_1644 putative cdk-activating kinase assembly factor mat1 protein\tK10842 MNAT1; CDK-activating kinase assembly factor MAT1"
					}
					]
				},
				{
					"name":"RPA (replication factor A)",
					"children":[
					{
						"name":"UCREL1_8056 putative replication factor-a protein 1 protein\tK07466 RFA1; replication factor A1"
					},
					{
						"name":"UCREL1_7028 putative replication protein a 32 kda subunit protein\tK10739 RFA2; replication factor A2"
					},
					{
						"name":"UCREL1_5449 putative replication factor a protein 3 protein\tK10740 RPA3; replication factor A3"
					}
					]
				},
				{
					"name":"Other NER factors",
					"children":[
					{
						"name":"UCREL1_1155 putative dna repair protein rad14 protein\tK10847 XPA; DNA-repair protein complementing XP-A cells"
					},
					{
						"name":"UCREL1_2699 putative mating-type switching protein swi10 protein\tK10849 ERCC1; DNA excision repair protein ERCC-1"
					},
					{
						"name":"UCREL1_8941 putative dna repair protein\tK10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]"
					},
					{
						"name":"UCREL1_3184 putative dna excision repair protein rad2 protein\tK10846 ERCC5; DNA excision repair protein ERCC-5"
					},
					{
						"name":"UCREL1_546 putative dna ligase protein\tK10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]"
					},
					{
						"name":"UCREL1_932 putative cytosolic iron-sulfur protein assembly protein 1 protein\tK24730 CIAO1; cytosolic iron-sulfur protein assembly protein CIAO1"
					},
					{
						"name":"UCREL1_4847 putative cullulin 3 protein\tK03869 CUL3; cullin 3"
					},
					{
						"name":"UCREL1_4809 putative skp1 family protein\tK03872 ELOC; elongin-C"
					},
					{
						"name":"UCREL1_3509 putative rna polymerase ii transcription factor siii subunit a protein\tK15077 ELA1; elongin-A"
					}
					]
				}
				]
			},
			{
				"name":"MMR (mismatch excision repair)",
				"children":[
				{
					"name":"Mismatch and loop recognition factors",
					"children":[
					{
						"name":"UCREL1_10471 putative dna mismatch repair protein msh-2 protein\tK08735 MSH2; DNA mismatch repair protein MSH2"
					},
					{
						"name":"UCREL1_8915 putative dna mismatch repair protein msh3 protein\tK08736 MSH3; DNA mismatch repair protein MSH3"
					},
					{
						"name":"UCREL1_7088 putative dna mismatch repair protein msh6 protein\tK08737 MSH6; DNA mismatch repair protein MSH6"
					}
					]
				},
				{
					"name":"MutL homologs",
					"children":[
					{
						"name":"UCREL1_1897 putative dna mismatch repair protein\tK08734 MLH1; DNA mismatch repair protein MLH1"
					},
					{
						"name":"UCREL1_8204 putative dna mismatch repair protein\tK10858 PMS2; DNA mismatch repair protein PMS2"
					},
					{
						"name":"UCREL1_2608 putative dna mismatch repair protein\tK08739 MLH3; DNA mismatch repair protein MLH3"
					}
					]
				},
				{
					"name":"DNA polymerase delta complex",
					"children":[
					{
						"name":"UCREL1_220 putative dna polymerase delta catalytic subunit protein\tK02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]"
					},
					{
						"name":"UCREL1_370 putative dna polymerase delta small subunit protein\tK02328 POLD2; DNA polymerase delta subunit 2"
					},
					{
						"name":"UCREL1_4138 putative dna polymerase subunit cdc27 protein\tK03504 POLD3; DNA polymerase delta subunit 3"
					},
					{
						"name":"UCREL1_5998 putative dna polymerase delta protein\tK03505 POLD4; DNA polymerase delta subunit 4"
					}
					]
				},
				{
					"name":"RPA (replication factor A)",
					"children":[
					{
						"name":"UCREL1_8056 putative replication factor-a protein 1 protein\tK07466 RFA1; replication factor A1"
					},
					{
						"name":"UCREL1_7028 putative replication protein a 32 kda subunit protein\tK10739 RFA2; replication factor A2"
					},
					{
						"name":"UCREL1_5449 putative replication factor a protein 3 protein\tK10740 RPA3; replication factor A3"
					}
					]
				},
				{
					"name":"RFC (replication factor C)",
					"children":[
					{
						"name":"UCREL1_5844 putative replication factor rfc1 c terminal domain-containing protein\tK10754 RFC1; replication factor C subunit 1"
					},
					{
						"name":"UCREL1_11509 putative activator 1 41 kda subunit protein\tK10755 RFC2_4; replication factor C subunit 2\/4"
					},
					{
						"name":"UCREL1_11696 putative activator 1 38 kda subunit protein\tK10756 RFC3_5; replication factor C subunit 3\/5"
					},
					{
						"name":"UCREL1_3443 putative replication factor c subunit 3 protein\tK10756 RFC3_5; replication factor C subunit 3\/5"
					}
					]
				},
				{
					"name":"Other MMR factors",
					"children":[
					{
						"name":"UCREL1_1256 putative proliferating cell nuclear antigen protein\tK04802 PCNA; proliferating cell nuclear antigen"
					},
					{
						"name":"UCREL1_3201 putative exonuclease 1 protein\tK10746 EXO1; exonuclease 1 [EC:3.1.-.-]"
					},
					{
						"name":"UCREL1_546 putative dna ligase protein\tK10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]"
					},
					{
						"name":"UCREL1_3815 putative wd repeat-containing protein\tK24755 WDR76; WD repeat-containing protein 76"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"DSBR (double strand breaks repair)",
			"children":[
			{
				"name":"HR (homologous recombination)",
				"children":[
				{
					"name":"MRN(MRX) complex",
					"children":[
					{
						"name":"UCREL1_512 putative dna repair protein rad32 protein\tK10865 MRE11; double-strand break repair protein MRE11"
					},
					{
						"name":"UCREL1_5409 putative rad50 protein\tK10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]"
					}
					]
				},
				{
					"name":"BRCA1-core complex"
				},
				{
					"name":"BRCA1-A complex"
				},
				{
					"name":"BRCA1-B complex"
				},
				{
					"name":"BRCA1-C complex",
					"children":[
					{
						"name":"UCREL1_512 putative dna repair protein rad32 protein\tK10865 MRE11; double-strand break repair protein MRE11"
					},
					{
						"name":"UCREL1_5409 putative rad50 protein\tK10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]"
					}
					]
				},
				{
					"name":"BRCA complex",
					"children":[
					{
						"name":"UCREL1_6622 putative dna repair protein rad51 protein\tK04482 RAD51; DNA repair protein RAD51"
					}
					]
				},
				{
					"name":"RecA family proteins",
					"children":[
					{
						"name":"UCREL1_6622 putative dna repair protein rad51 protein\tK04482 RAD51; DNA repair protein RAD51"
					},
					{
						"name":"UCREL1_1039 putative dna repair protein\tK10958 RAD57; DNA repair protein RAD57"
					}
					]
				},
				{
					"name":"Rad52 family proteins",
					"children":[
					{
						"name":"UCREL1_8548 putative rad52 dna repair protein radc protein\tK10873 RAD52; DNA repair and recombination protein RAD52"
					}
					]
				},
				{
					"name":"Rad54 family proteins",
					"children":[
					{
						"name":"UCREL1_7726 putative dna repair and recombination protein rad54 protein\tK10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]"
					}
					]
				},
				{
					"name":"RecQ family DNA helicases"
				},
				{
					"name":"Bloom's syndrome complex (BTR)",
					"children":[
					{
						"name":"UCREL1_4621 putative dna topoisomerase iii protein\tK03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]"
					},
					{
						"name":"UCREL1_10362 putative mediated genome instability protein rmi1 protein\tK15364 NCE4; RecQ-mediated genome instability protein 1"
					}
					]
				},
				{
					"name":"RPA (replication factor A)",
					"children":[
					{
						"name":"UCREL1_8056 putative replication factor-a protein 1 protein\tK07466 RFA1; replication factor A1"
					},
					{
						"name":"UCREL1_7028 putative replication protein a 32 kda subunit protein\tK10739 RFA2; replication factor A2"
					},
					{
						"name":"UCREL1_5449 putative replication factor a protein 3 protein\tK10740 RPA3; replication factor A3"
					}
					]
				},
				{
					"name":"Protein phosphatase 4",
					"children":[
					{
						"name":"UCREL1_2845 putative suppressor of mek1 protein\tK17491 SMEK; protein phosphatase 4 regulatory subunit 3"
					}
					]
				},
				{
					"name":"AP-5 complex"
				},
				{
					"name":"SMC5-SMC6 complex",
					"children":[
					{
						"name":"UCREL1_9044 putative structural maintenance of chromosome complex subunit protein\tK22803 SMC5; structural maintenance of chromosomes protein 5"
					},
					{
						"name":"UCREL1_9785 putative dna repair protein\tK22804 SMC6; structural maintenance of chromosomes protein 6"
					},
					{
						"name":"UCREL1_9627 putative dna repair protein\tK22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27]"
					},
					{
						"name":"UCREL1_8214 putative chromosomal organization and dna repair protein\tK22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]"
					},
					{
						"name":"UCREL1_3307 putative nuclear protein qri2 protein\tK22825 NSMCE4; non-structural maintenance of chromosomes element 4"
					}
					]
				},
				{
					"name":"Other HR factors",
					"children":[
					{
						"name":"UCREL1_6112 putative ercc4 domain-containing protein\tK10882 EME1; crossover junction endonuclease EME1 [EC:3.1.22.-]"
					},
					{
						"name":"UCREL1_1712 putative crossover junction endonuclease mus81 protein\tK08991 MUS81; crossover junction endonuclease MUS81 [EC:3.1.22.-]"
					},
					{
						"name":"UCREL1_4442 hypothetical protein\tK10881 SHFM1; 26 proteasome complex subunit DSS1"
					},
					{
						"name":"UCREL1_8608 putative flap structure-specific endonuclease protein\tK15338 GEN1; holliday junction resolvase GEN1\/YEN1 [EC:3.1.-.-]"
					},
					{
						"name":"UCREL1_8849 putative flap structure-specific endonuclease protein\tK15338 GEN1; holliday junction resolvase GEN1\/YEN1 [EC:3.1.-.-]"
					},
					{
						"name":"UCREL1_10604 putative keratinolytic protein\tK11339 MORF4L1; mortality factor 4-like protein 1"
					},
					{
						"name":"UCREL1_9786 putative aaa family atpase protein\tK22766 FIGNL1; fidgetin-like protein 1 [EC:5.6.2.-]"
					}
					]
				}
				]
			},
			{
				"name":"NHEJ (non-homologous end-joining)",
				"children":[
				{
					"name":"DNA-PK complex",
					"children":[
					{
						"name":"UCREL1_9614 putative ku70 protein\tK10884 XRCC6; ATP-dependent DNA helicase 2 subunit 1"
					},
					{
						"name":"UCREL1_4617 putative ku family dna protein\tK10885 XRCC5; ATP-dependent DNA helicase 2 subunit 2"
					}
					]
				},
				{
					"name":"MRX complex",
					"children":[
					{
						"name":"UCREL1_512 putative dna repair protein rad32 protein\tK10865 MRE11; double-strand break repair protein MRE11"
					},
					{
						"name":"UCREL1_5409 putative rad50 protein\tK10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]"
					}
					]
				},
				{
					"name":"DNA Ligase 4 complex",
					"children":[
					{
						"name":"UCREL1_10106 putative dna ligase i protein\tK10777 LIG4; DNA ligase 4 [EC:6.5.1.1]"
					},
					{
						"name":"UCREL1_9418 putative atp-dependent dna ligase domain-containing protein\tK10777 LIG4; DNA ligase 4 [EC:6.5.1.1]"
					}
					]
				},
				{
					"name":"X-family DNA polymerases",
					"children":[
					{
						"name":"UCREL1_1708 putative dna polymerase protein\tK10981 POL4; DNA polymerase IV [EC:2.7.7.7]"
					},
					{
						"name":"UCREL1_1947 putative dna polymerase beta protein\tK10981 POL4; DNA polymerase IV [EC:2.7.7.7]"
					}
					]
				},
				{
					"name":"Other NHEJ factors",
					"children":[
					{
						"name":"UCREL1_4929 putative aprataxin-like protein\tK10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]"
					},
					{
						"name":"UCREL1_10739 putative artemis protein\tK10887 DCLRE1C; DNA cross-link repair 1C protein [EC:3.1.-.-]"
					},
					{
						"name":"UCREL1_10911 putative endonuclease exonuclease phosphatase family protein\tK19619 TDP2; tyrosyl-DNA phosphodiesterase 2 [EC:3.1.4.-]"
					},
					{
						"name":"UCREL1_2078 putative endonuclease exonuclease phosphatase family protein\tK19619 TDP2; tyrosyl-DNA phosphodiesterase 2 [EC:3.1.4.-]"
					},
					{
						"name":"UCREL1_3902 putative endonuclease exonuclease phosphatase family protein\tK19619 TDP2; tyrosyl-DNA phosphodiesterase 2 [EC:3.1.4.-]"
					},
					{
						"name":"UCREL1_5558 putative endonuclease exonuclease phosphatase family protein\tK19619 TDP2; tyrosyl-DNA phosphodiesterase 2 [EC:3.1.4.-]"
					}
					]
				}
				]
			},
			{
				"name":"FA (Fanconi anemia) pathway",
				"children":[
				{
					"name":"FA core complex"
				},
				{
					"name":"FA core complex binding factors"
				},
				{
					"name":"Bloom's syndrome complex (BTR)",
					"children":[
					{
						"name":"UCREL1_4621 putative dna topoisomerase iii protein\tK03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]"
					},
					{
						"name":"UCREL1_10362 putative mediated genome instability protein rmi1 protein\tK15364 NCE4; RecQ-mediated genome instability protein 1"
					}
					]
				},
				{
					"name":"FANCD2-I complex"
				},
				{
					"name":"Downstream FA components"
				},
				{
					"name":"Other FA pathway factors",
					"children":[
					{
						"name":"UCREL1_6622 putative dna repair protein rad51 protein\tK04482 RAD51; DNA repair protein RAD51"
					},
					{
						"name":"UCREL1_9847 putative telomere length regulation protein\tK11137 TELO2; telomere length regulation protein"
					},
					{
						"name":"UCREL1_937 putative wd repeat-containing protein 5b protein\tK15361 WDR48; WD repeat-containing protein 48"
					}
					]
				}
				]
			},
			{
				"name":"Other DSBR factors",
				"children":[
				{
					"name":"Protein phosphatase 6"
				},
				{
					"name":"Ubiquitin ligases"
				},
				{
					"name":"Others",
					"children":[
					{
						"name":"UCREL1_303 putative wd repeat domain-containing protein\tK23314 WRAP53; telomerase Cajal body protein 1"
					},
					{
						"name":"UCREL1_8918 putative wd repeat-containing protein 70 protein\tK24752 WDR70; WD repeat-containing protein 70"
					},
					{
						"name":"UCREL1_3815 putative wd repeat-containing protein\tK24755 WDR76; WD repeat-containing protein 76"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"TLS (translesion DNA synthesis) factors",
			"children":[
			{
				"name":"Y-family DNA polymerases",
				"children":[
				{
					"name":"UCREL1_6540 putative dna polymerase iota protein\tK03510 POLI; DNA polymerase iota [EC:2.7.7.7]"
				},
				{
					"name":"UCREL1_440 putative impb mucb samb family protein\tK03511 POLK; DNA polymerase kappa [EC:2.7.7.7]"
				},
				{
					"name":"UCREL1_10853 putative dna polymerase iv protein\tK03515 REV1; DNA repair protein REV1 [EC:2.7.7.-]"
				}
				]
			},
			{
				"name":"B-family DNA polymerases"
			},
			{
				"name":"A-family DNA polymerase"
			},
			{
				"name":"Rad6 epistasis group",
				"children":[
				{
					"name":"UCREL1_2448 putative ubiquitin-conjugating enzyme e2 2 protein\tK10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]"
				},
				{
					"name":"UCREL1_4137 putative dna repair protein rad18 protein\tK10627 RAD18; E3 ubiquitin-protein ligase RAD18 [EC:2.3.2.27]"
				},
				{
					"name":"UCREL1_2359 putative dna repair protein rad5 protein\tK15505 RAD5; DNA repair protein RAD5 [EC:5.6.2.-]"
				},
				{
					"name":"UCREL1_11605 putative rad5-like protein\tK15711 SMARCA3; SWI\/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A3 [EC:5.6.2. 2.3.2.27]"
				},
				{
					"name":"UCREL1_7639 putative ubiquitin conjugating enzyme protein\tK10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]"
				}
				]
			},
			{
				"name":"Other TLS factors",
				"children":[
				{
					"name":"UCREL1_1256 putative proliferating cell nuclear antigen protein\tK04802 PCNA; proliferating cell nuclear antigen"
				},
				{
					"name":"UCREL1_7715 putative hmg box-containing protein\tK26957 GCNA; germ cell nuclear acidic protein"
				}
				]
			}
			]
		},
		{
			"name":"Check point factors",
			"children":[
			{
				"name":"Rad9-Hus1-Rad1 complex",
				"children":[
				{
					"name":"UCREL1_2153 putative dna repair protein rad9 protein\tK10994 RAD9A; cell cycle checkpoint control protein RAD9A [EC:3.1.11.2]"
				},
				{
					"name":"UCREL1_154 putative checkpoint protein hus1 protein\tK10903 HUS1; HUS1 checkpoint protein"
				},
				{
					"name":"UCREL1_8136 putative dna repair exonuclease rad1 protein\tK02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]"
				}
				]
			},
			{
				"name":"HRAD17(Rad24)-RFC complex",
				"children":[
				{
					"name":"UCREL1_11509 putative activator 1 41 kda subunit protein\tK10755 RFC2_4; replication factor C subunit 2\/4"
				},
				{
					"name":"UCREL1_11696 putative activator 1 38 kda subunit protein\tK10756 RFC3_5; replication factor C subunit 3\/5"
				},
				{
					"name":"UCREL1_3443 putative replication factor c subunit 3 protein\tK10756 RFC3_5; replication factor C subunit 3\/5"
				}
				]
			},
			{
				"name":"Rad17-Mec3-Ddc1 complex",
				"children":[
				{
					"name":"UCREL1_8136 putative dna repair exonuclease rad1 protein\tK02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]"
				}
				]
			},
			{
				"name":"FPC (fork protection complex)",
				"children":[
				{
					"name":"UCREL1_9407 putative topoisomerase 1-associated factor 1 protein\tK10997 TIMELESS; replication fork protection complex subunit TIMELESS\/Tof1\/Swi1"
				},
				{
					"name":"UCREL1_6038 putative chromosome segregation in meiosis protein 3 protein\tK10998 TIPIN; replication fork protection complex subunit TIPIN\/Csm3\/Swi3"
				},
				{
					"name":"UCREL1_6266 putative mrc1-like domain-containing protein\tK11272 MRC1; mediator of replication checkpoint protein 1"
				}
				]
			},
			{
				"name":"Triple T complex",
				"children":[
				{
					"name":"UCREL1_9847 putative telomere length regulation protein\tK11137 TELO2; telomere length regulation protein"
				}
				]
			},
			{
				"name":"BAG6-UBL4A-GET4 complex",
				"children":[
				{
					"name":"UCREL1_11334 putative ubiquitin supergroup protein\tK23388 UBL4; ubiquitin-like protein 4"
				},
				{
					"name":"UCREL1_9495 putative duf410 domain-containing protein\tK23387 GET4; golgi to ER traffic protein 4"
				}
				]
			},
			{
				"name":"SOSS complex"
			},
			{
				"name":"Other check point factors",
				"children":[
				{
					"name":"UCREL1_2635 putative protein kinase rad3 protein\tK06640 ATR; serine\/threonine-protein kinase ATR [EC:2.7.11.1]"
				},
				{
					"name":"UCREL1_5676 putative ataxia telangiectasia mutated protein\tK04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]"
				},
				{
					"name":"UCREL1_9719 putative serine threonine-protein kinase chk1 protein\tK02216 CHEK1; serine\/threonine-protein kinase CHEK1 [EC:2.7.11.1]"
				},
				{
					"name":"UCREL1_4154 putative checkpoint kinase 2-like protein\tK06641 CHEK2; serine\/threonine-protein kinase CHEK2 [EC:2.7.11.1]"
				},
				{
					"name":"UCREL1_3014 putative m-phase inducer phosphatase protein\tK02555 MIH1; M-phase inducer tyrosine phosphatase [EC:3.1.3.48]"
				},
				{
					"name":"UCREL1_11014 putative 14-3-3 protein\tK06630 YWHAE; 14-3-3 protein epsilon"
				},
				{
					"name":"UCREL1_1245 putative dna damage checkpoint protein rad24 protein\tK06630 YWHAE; 14-3-3 protein epsilon"
				},
				{
					"name":"UCREL1_2890 putative fork head domain-containing protein\tK24664 FKH; forkhead protein FKH"
				},
				{
					"name":"UCREL1_5031 putative vacuolar sorting atpase protein\tK12196 VPS4; vacuolar protein-sorting-associated protein 4"
				},
				{
					"name":"UCREL1_1756 putative ubiquitin family protein\tK25059 SDE2; replication stress response regulator SDE2"
				}
				]
			}
			]
		},
		{
			"name":"Other factors with a suspected DNA repair function",
			"children":[
			{
				"name":"DNA polymerases",
				"children":[
				{
					"name":"UCREL1_3018 putative dna polymerase protein\tK02331 POL5; DNA polymerase phi [EC:2.7.7.7]"
				}
				]
			},
			{
				"name":"Nucleases",
				"children":[
				{
					"name":"UCREL1_7991 putative dna cross-link repair protein snm1 protein\tK15340 DCLRE1A; DNA cross-link repair 1A protein"
				},
				{
					"name":"UCREL1_2123 putative nuclease s1 protein\tK05986 NUCS; nuclease S1 [EC:3.1.30.1]"
				}
				]
			},
			{
				"name":"Helicases",
				"children":[
				{
					"name":"UCREL1_1128 putative dna excision repair protein\tK20098 ERCC6L2; DNA excision repair protein ERCC-6-like 2 [EC:5.6.2.-]"
				}
				]
			},
			{
				"name":"PSO4 complex",
				"children":[
				{
					"name":"UCREL1_1980 putative cell cycle control protein\tK10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]"
				},
				{
					"name":"UCREL1_10903 putative pre-mrna-splicing factor cef-1 protein\tK12860 CDC5L; pre-mRNA-splicing factor CDC5\/CEF1"
				},
				{
					"name":"UCREL1_6984 putative bcas2 family protein\tK12861 BCAS2; pre-mRNA-splicing factor SPF27"
				},
				{
					"name":"UCREL1_3795 putative pre-mrna splicing protein\tK12862 PLRG1; pleiotropic regulator 1"
				}
				]
			},
			{
				"name":"Modulation of nucleotide pools",
				"children":[
				{
					"name":"UCREL1_2728 putative nudix domain containing protein\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]"
				},
				{
					"name":"UCREL1_1254 putative deoxyuridine 5 -triphosphate nucleotidohydrolase protein\tK01520 dut; dUTP diphosphatase [EC:3.6.1.23]"
				},
				{
					"name":"UCREL1_2597 putative ribonucleoside-diphosphate reductase large chain protein\tK10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]"
				},
				{
					"name":"UCREL1_2515 putative ribonucleoside-diphosphate reductase small subunit protein\tK10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic type",
		"children":[
		{
			"name":"SSBR (single strand breaks repair)",
			"children":[
			{
				"name":"Direct repair",
				"children":[
				{
					"name":"UCREL1_5984 putative ring-2 protein\tK00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]"
				},
				{
					"name":"UCREL1_1319 putative deoxyribodipyrimidine photo-lyase protein\tK01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]"
				}
				]
			},
			{
				"name":"BER (base exicision repair)",
				"children":[
				{
					"name":"DNA glycosylases",
					"children":[
					{
						"name":"UCREL1_3974 putative uracil-dna glycosylase protein\tK03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]"
					},
					{
						"name":"UCREL1_4935 putative -gpd superfamily base excision dna repair protein\tK01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]"
					},
					{
						"name":"UCREL1_5901 putative a g-specific adenine glycosylase protein\tK03575 mutY; A\/G-specific adenine glycosylase [EC:3.2.2.31]"
					},
					{
						"name":"UCREL1_5934 putative formamidopyrimidine-dna glycosylase protein\tK10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]"
					},
					{
						"name":"UCREL1_9365 putative dna repair protein ntg1 protein\tK10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]"
					}
					]
				},
				{
					"name":"AP endonucleases"
				},
				{
					"name":"RecJ"
				},
				{
					"name":"DNA ligase"
				},
				{
					"name":"DNA polymerase I"
				}
				]
			},
			{
				"name":"NER (nucleotide excision repair)",
				"children":[
				{
					"name":"GGR (global genome repair) factors"
				},
				{
					"name":"TCR (transcription coupled repair) factors",
					"children":[
					{
						"name":"DNA-directed RNA polymerase complex (RNAP)"
					},
					{
						"name":"TRCF (transcription-repair coupling factor)"
					}
					]
				}
				]
			},
			{
				"name":"MMR (mismatch excision repair)",
				"children":[
				{
					"name":"Mismatch and loop recognition factors"
				},
				{
					"name":"Molecular matchmaker"
				},
				{
					"name":"Strand discrimination factor"
				},
				{
					"name":"DNA exonucleases"
				},
				{
					"name":"DNA polymerase III holoenzyme"
				},
				{
					"name":"DNA ligase"
				},
				{
					"name":"Other MMR factors"
				}
				]
			}
			]
		},
		{
			"name":"DSBR (double strand breaks repair)",
			"children":[
			{
				"name":"HR (homologous recombination)",
				"children":[
				{
					"name":"RecBC pathway proteins"
				},
				{
					"name":"RecFOR pathway proteins"
				},
				{
					"name":"AddAB pathway proteins"
				},
				{
					"name":"Other HR factor"
				},
				{
					"name":"Archaeal homologous recombinant proteins"
				}
				]
			},
			{
				"name":"NHEJ (non-homologous end-joining)",
				"children":[
				{
					"name":"Two-component NHEJ DNA repair complex"
				},
				{
					"name":"SHIIR (short-homology-independent illegitimate recombination)",
					"children":[
					{
						"name":"Facilitator"
					},
					{
						"name":"Supressor"
					}
					]
				},
				{
					"name":"SHDIR (short-homology-dependent illegitimate recombination)",
					"children":[
					{
						"name":"RecET pathway"
					},
					{
						"name":"Facilitator"
					},
					{
						"name":"Supressor"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"TLS (translesion DNA synthesis) factors",
			"children":[
			{
				"name":"Y-family DNA polymerases"
			},
			{
				"name":"Other SOS response factors"
			}
			]
		},
		{
			"name":"Other factors with a suspected DNA repair function",
			"children":[
			{
				"name":"DNA polymerase"
			},
			{
				"name":"DNA helicases"
			},
			{
				"name":"Modulation of nucleotide pools",
				"children":[
				{
					"name":"UCREL1_2728 putative nudix domain containing protein\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]"
				},
				{
					"name":"UCREL1_1254 putative deoxyuridine 5 -triphosphate nucleotidohydrolase protein\tK01520 dut; dUTP diphosphatase [EC:3.6.1.23]"
				}
				]
			},
			{
				"name":"Others"
			}
			]
		}
		]
	}
	]
}
