{
	"name":"eoh01001",
	"children":[
	{
		"name":"Serine\/threonine kinases: AGC group",
		"children":[
		{
			"name":"PKA family"
		},
		{
			"name":"PKG family"
		},
		{
			"name":"PKC family [OT]"
		},
		{
			"name":"PKN family"
		},
		{
			"name":"AUR family [OT]"
		},
		{
			"name":"PDK1 family"
		},
		{
			"name":"AKT\/PKB family"
		},
		{
			"name":"SGK family [OT]"
		},
		{
			"name":"RSK family [OT]"
		},
		{
			"name":"NDR family"
		},
		{
			"name":"MAST family [OT]"
		},
		{
			"name":"YANK family"
		},
		{
			"name":"DMPK family [OT]"
		},
		{
			"name":"GRK family [OT]"
		},
		{
			"name":"Other"
		}
		]
	},
	{
		"name":"Serine\/threonine kinases: CAMK group",
		"children":[
		{
			"name":"CAMK1 family [OT]"
		},
		{
			"name":"CAMK2 family"
		},
		{
			"name":"CAMKL family"
		},
		{
			"name":"DAPK family"
		},
		{
			"name":"DCAMKL family"
		},
		{
			"name":"MAPKAPK family [OT]"
		},
		{
			"name":"MLCK family"
		},
		{
			"name":"PHK family"
		},
		{
			"name":"PIM family [OT]"
		},
		{
			"name":"PKD family"
		},
		{
			"name":"PSK family"
		},
		{
			"name":"RAD53 family"
		},
		{
			"name":"Trio family [OT]"
		},
		{
			"name":"TSSK family"
		},
		{
			"name":"CDPK family"
		},
		{
			"name":"CASK family"
		},
		{
			"name":"Trbl family"
		},
		{
			"name":"Other"
		}
		]
	},
	{
		"name":"Serine\/threonine kinases: CK1 group",
		"children":[
		{
			"name":"CK1 family [OT]"
		},
		{
			"name":"TTBK family"
		},
		{
			"name":"VRK family"
		}
		]
	},
	{
		"name":"Serine\/threonine kinases: CMGC group",
		"children":[
		{
			"name":"CDK family"
		},
		{
			"name":"MAPK family [OT]"
		},
		{
			"name":"GSK family [OT]"
		},
		{
			"name":"CLK family"
		},
		{
			"name":"CDKL family"
		},
		{
			"name":"DYRK family [OT]"
		},
		{
			"name":"RCK family [OT]"
		},
		{
			"name":"SRPK family [OT]"
		}
		]
	},
	{
		"name":"Serine\/threonine kinases: STE group",
		"children":[
		{
			"name":"STE7 family"
		},
		{
			"name":"STE20 family"
		},
		{
			"name":"STE11 family"
		},
		{
			"name":"Other"
		}
		]
	},
	{
		"name":"Serine\/threonine kinases: TKL group",
		"children":[
		{
			"name":"IRAK family"
		},
		{
			"name":"LISK family [OT]"
		},
		{
			"name":"LRRK family"
		},
		{
			"name":"MLK family"
		},
		{
			"name":"RAF family [OT]"
		},
		{
			"name":"RIPK family [OT]"
		},
		{
			"name":"Other"
		}
		]
	},
	{
		"name":"Serine\/threonine kinases: Other",
		"children":[
		{
			"name":"RGC family [OT]"
		},
		{
			"name":"BUB family"
		},
		{
			"name":"Bud32 family"
		},
		{
			"name":"CAMKK family"
		},
		{
			"name":"CDC7 family"
		},
		{
			"name":"CK2 family"
		},
		{
			"name":"Haspin family"
		},
		{
			"name":"IKK family [OT]"
		},
		{
			"name":"IRE family"
		},
		{
			"name":"MOS family"
		},
		{
			"name":"NAK family [OT]"
		},
		{
			"name":"NEK family"
		},
		{
			"name":"NKF1 family"
		},
		{
			"name":"NKF2 family"
		},
		{
			"name":"NKF3 family"
		},
		{
			"name":"NKF4 family"
		},
		{
			"name":"NKF5 family"
		},
		{
			"name":"NRBP family"
		},
		{
			"name":"PEK family [OT]"
		},
		{
			"name":"PLK family [OT]"
		},
		{
			"name":"SCY1 family [OT]"
		},
		{
			"name":"Slob family"
		},
		{
			"name":"TBCK family"
		},
		{
			"name":"TLK family"
		},
		{
			"name":"TOPK family"
		},
		{
			"name":"TTK family"
		},
		{
			"name":"ULK family [OT]"
		},
		{
			"name":"VPS15 family"
		},
		{
			"name":"WEE family"
		},
		{
			"name":"Wnk family"
		},
		{
			"name":"ABC1 family"
		},
		{
			"name":"Alpha family [OT]"
		},
		{
			"name":"BCR family"
		},
		{
			"name":"BRD family [OT]"
		},
		{
			"name":"FAST family"
		},
		{
			"name":"G11 family"
		},
		{
			"name":"H11 family"
		},
		{
			"name":"PDHK family [OT]"
		},
		{
			"name":"PIKK family [OT]"
		},
		{
			"name":"RIO family [OT]"
		},
		{
			"name":"TAF1 family"
		},
		{
			"name":"TIF1 family [OT]"
		},
		{
			"name":"Other"
		},
		{
			"name":"Bacterial family",
			"children":[
			{
				"name":"ECO103_1374 hypothetical protein\tK12132 prkC; eukaryotic-like serine\/threonine-protein kinase [EC:2.7.11.1]"
			},
			{
				"name":"ECO103_1638 hipA; regulator with hipB\tK07154 hipA; serine\/threonine-protein kinase HipA [EC:2.7.11.1]"
			}
			]
		}
		]
	},
	{
		"name":"Receptor serine\/threonine kinases (RSTK): TKL group",
		"children":[
		{
			"name":"TGFBR1 family [OT]"
		},
		{
			"name":"TGFBR2 family [OT]"
		}
		]
	},
	{
		"name":"Receptor tyrosine kinases (RTK)",
		"children":[
		{
			"name":"EGFR family [OT]"
		},
		{
			"name":"INSR family [OT]"
		},
		{
			"name":"PDGFR family [OT]"
		},
		{
			"name":"FGFR family [OT]"
		},
		{
			"name":"VEGFR family [OT]"
		},
		{
			"name":"MET family"
		},
		{
			"name":"TRK family [OT]"
		},
		{
			"name":"EPH family [OT]"
		},
		{
			"name":"AXL family"
		},
		{
			"name":"ALK family"
		},
		{
			"name":"TIE family"
		},
		{
			"name":"ROR family"
		},
		{
			"name":"DDR family"
		},
		{
			"name":"RET family"
		},
		{
			"name":"ROS family"
		},
		{
			"name":"CCK family"
		},
		{
			"name":"RYK family"
		},
		{
			"name":"MUSK family"
		},
		{
			"name":"LMR family [OT]"
		}
		]
	},
	{
		"name":"Non-receptor tyrosine kinases",
		"children":[
		{
			"name":"ABL family"
		},
		{
			"name":"ACK family"
		},
		{
			"name":"CSK family"
		},
		{
			"name":"FAK family"
		},
		{
			"name":"FES family"
		},
		{
			"name":"JAK family [OT]"
		},
		{
			"name":"SRC family"
		},
		{
			"name":"TEC family"
		},
		{
			"name":"SYK family"
		},
		{
			"name":"Other"
		},
		{
			"name":"Bacterial",
			"children":[
			{
				"name":"ECO103_1026 yccC; cryptic autophosphorylating protein tyrosine kinase Etk\tK16692 etk-wzc; tyrosine-protein kinase Etk\/Wzc [EC:2.7.10.3]"
			},
			{
				"name":"ECO103_2539 wzc; protein-tyrosine kinase Wzc\tK16692 etk-wzc; tyrosine-protein kinase Etk\/Wzc [EC:2.7.10.3]"
			}
			]
		}
		]
	},
	{
		"name":"Histidine kinases",
		"children":[
		{
			"name":"OmpR family",
			"children":[
			{
				"name":"ECO103_0374 phoR; sensory histidine kinase PhoR in two-component regulatory system with PhoB\tK07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]"
			},
			{
				"name":"ECO103_1253 phoQ; sensory histidine kinase PhoQ in two-component regulatory system with PhoP\tK07637 phoQ; two-component system, OmpR family, sensor histidine kinase PhoQ [EC:2.7.13.3]"
			},
			{
				"name":"ECO103_4122 envZ; sensory histidine kinase EnvZ in two-component regulatory system with OmpR\tK07638 envZ; two-component system, OmpR family, osmolarity sensor histidine kinase EnvZ [EC:2.7.13.3]"
			},
			{
				"name":"ECO103_1749 rstB; sensory histidine kinase RstB in two-component regulatory system with RstA\tK07639 rstB; two-component system, OmpR family, sensor histidine kinase RstB [EC:2.7.13.3]"
			},
			{
				"name":"ECO103_4616 cpxA; sensory histidine kinase CpxA in two-component regulatory system with CpxR\tK07640 cpxA; two-component system, OmpR family, sensor histidine kinase CpxA [EC:2.7.13.3]"
			},
			{
				"name":"ECO103_5260 creC; sensory histidine kinase CreC in two-component regulatory system with CreB or PhoB, regulator of the CreBC regulon\tK07641 creC; two-component system, OmpR family, sensor histidine kinase CreC [EC:2.7.13.3]"
			},
			{
				"name":"ECO103_2556 baeS; sensory histidine kinase BaeS in two-component regulatory system with BaeR\tK07642 baeS; two-component system, OmpR family, sensor histidine kinase BaeS [EC:2.7.13.3]"
			},
			{
				"name":"ECO103_4864 basS; sensory histidine kinase BasS in two-component regulatory system with BasR\tK07643 basS; two-component system, OmpR family, sensor histidine kinase BasS [EC:2.7.13.3]"
			},
			{
				"name":"ECO103_0575 cusS; sensory histidine kinase CusS in two-component regulatory system with CusR, senses copper ions\tK07644 cusS; two-component system, OmpR family, heavy metal sensor histidine kinase CusS [EC:2.7.13.3]"
			},
			{
				"name":"ECO103_3704 qseC; sensory histidine kinase QseC in two-component regulatory system with QseB\tK07645 qseC; two-component system, OmpR family, sensor histidine kinase QseC [EC:2.7.13.3]"
			},
			{
				"name":"ECO103_0689 kdpD; fused sensory histidine kinase KdpD in two-component regulatory system with KdpE: signal sensing protein\tK07646 kdpD; two-component system, OmpR family, sensor histidine kinase KdpD [EC:2.7.13.3]"
			},
			{
				"name":"ECO103_1038 torS; hybrid sensory histidine kinase TolS in two-component regulatory system with TorR\tK07647 torS; two-component system, OmpR family, sensor histidine kinase TorS [EC:2.7.13.3]"
			},
			{
				"name":"ECO103_3957 arcB; hybrid sensory histidine kinase ArcB in two-component regulatory system with ArcA\tK07648 arcB; two-component system, OmpR family, aerobic respiration control sensor histidine kinase ArcB [EC:2.7.13.3]"
			},
			{
				"name":"ECO103_2216 yedV; predicted sensory kinase in two-component regulatory system with YedW\tK02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3]"
			}
			]
		},
		{
			"name":"NarL family",
			"children":[
			{
				"name":"ECO103_1327 narX; sensory histidine kinase NarX in two-component regulatory system with NarL\tK07673 narX; two-component system, NarL family, nitrate\/nitrite sensor histidine kinase NarX [EC:2.7.13.3]"
			},
			{
				"name":"ECO103_2978 narQ; sensory histidine kinase NarQ\tK07674 narQ; two-component system, NarL family, nitrate\/nitrite sensor histidine kinase NarQ [EC:2.7.13.3]"
			},
			{
				"name":"ECO103_4489 uhpB; sensory histidine kinase UhpB in two-component regulatory sytem with UhpA\tK07675 uhpB; two-component system, NarL family, sensor histidine kinase UhpB [EC:2.7.13.3]"
			},
			{
				"name":"ECO103_2692 rcsD; phosphotransfer intermediate protein RcsD in two-component regulatory system with RcsBC\tK07676 rcsD; two-component system, NarL family, sensor histidine kinase RcsD [EC:2.7.13.3]"
			},
			{
				"name":"ECO103_2694 rcsC; hybrid sensory kinase RcsC in two-component regulatory system with RcsB and YojN\tK07677 rcsC; two-component system, NarL family, capsular synthesis sensor histidine kinase RcsC [EC:2.7.13.3]"
			},
			{
				"name":"ECO103_3329 barA; hybrid sensory histidine kinase BarY, in two-component regulatory system with UvrY\tK07678 barA; two-component system, NarL family, sensor histidine kinase BarA [EC:2.7.13.3]"
			},
			{
				"name":"ECO103_2895 evgS; hybrid sensory histidine kinase EvgS in two-component regulatory system with EvgA\tK07679 evgS; two-component system, NarL family, sensor histidine kinase EvgS [EC:2.7.13.3]"
			}
			]
		},
		{
			"name":"Spo family [OT]"
		},
		{
			"name":"CitB family [OT]",
			"children":[
			{
				"name":"ECO103_0627 citA; sensory histidine kinase CitA in two-component regulatory system with CitB\tK07700 dpiB; two-component system, CitB family, cit operon sensor histidine kinase CitA [EC:2.7.13.3]"
			},
			{
				"name":"ECO103_4877 dcuS; sensory histidine kinase DcuS in two-component regulatory system with DcuR, regulator of anaerobic fumarate respiration\tK07701 dcuS; two-component system, CitB family, sensor histidine kinase DcuS [EC:2.7.13.3]"
			}
			]
		},
		{
			"name":"LytTR family [OT]",
			"children":[
			{
				"name":"ECO103_2602 yehU; predicted sensory kinase in two-component system with YehT\tK27882 btsS; two-component system, LytTR family, low-concentration pyruvate sensor kinase [EC:2.7.13.3]"
			},
			{
				"name":"ECO103_2905 ypdA; predicted sensory kinase in two-component system with YpdB\tK27884 pyrS; two-component system, LytTR family, high-concentration pyruvate sensor kinase [EC:2.7.13.3]"
			}
			]
		},
		{
			"name":"NtrC family",
			"children":[
			{
				"name":"ECO103_4302 glnL; sensory histidine kinase GlnL in two-component regulatory system with GlnG\tK07708 glnL; two-component system, NtrC family, nitrogen regulation sensor histidine kinase GlnL [EC:2.7.13.3]"
			},
			{
				"name":"ECO103_4752 zraS; sensory histidine kinase ZraS in two-component regulatory system with ZraR\tK07709 zraS; two-component system, NtrC family, sensor histidine kinase HydH [EC:2.7.13.3]"
			},
			{
				"name":"ECO103_3077 yfhK; predicted sensory kinase in two-component system\tK07711 glrK; two-component system, NtrC family, sensor histidine kinase GlrK [EC:2.7.13.3]"
			}
			]
		},
		{
			"name":"CheA family [OT]",
			"children":[
			{
				"name":"ECO103_2150 cheA; fused chemotactic sensory histidine kinase in two-component regulatory system with CheB and CheY: sensory histidine kinase\/signal sensing protein\tK03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]"
			}
			]
		},
		{
			"name":"Cell cycle family [OT]"
		},
		{
			"name":"Lux family [OT]"
		},
		{
			"name":"LuxR family [OT]"
		},
		{
			"name":"Other"
		}
		]
	}
	]
}