{
	"name":"eta03009",
	"children":[
	{
		"name":"Eukaryotic type",
		"children":[
		{
			"name":"Sno RNPs",
			"children":[
			{
				"name":"Box C\/D snoRNPs"
			},
			{
				"name":"Box H\/ACA snoRNPs"
			}
			]
		},
		{
			"name":"90S particles",
			"children":[
			{
				"name":"U3 small nucleolar RNA-associated proteins"
			},
			{
				"name":"Helicases"
			},
			{
				"name":"GTPase"
			},
			{
				"name":"RNase",
				"children":[
				{
					"name":"ETA_09920 rnc; Ribonuclease III\tK03685 rnc; ribonuclease III [EC:3.1.26.3]"
				}
				]
			},
			{
				"name":"Kinase"
			},
			{
				"name":"Other 90S particles"
			}
			]
		},
		{
			"name":"Pre-40S particles",
			"children":[
			{
				"name":"Kinases"
			},
			{
				"name":"Export and cytoplasmic maturation factors"
			},
			{
				"name":"Other pre-40S particles"
			}
			]
		},
		{
			"name":"Pre-60S particles",
			"children":[
			{
				"name":"Helicases"
			},
			{
				"name":"GTPases"
			},
			{
				"name":"RNases",
				"children":[
				{
					"name":"ETA_29730 orn; Oligoribonuclease\tK13288 orn; oligoribonuclease [EC:3.1.-.-]"
				},
				{
					"name":"RNase MRP"
				}
				]
			},
			{
				"name":"Kinases"
			},
			{
				"name":"Export and cytoplasmic maturation factors"
			},
			{
				"name":"55LCC heterohexameric ATPase complex"
			},
			{
				"name":"5-FMC complex"
			},
			{
				"name":"Ribosome quality control proteins"
			},
			{
				"name":"Other pre-60S particles"
			}
			]
		},
		{
			"name":"Other ribosome biogenesis factors",
			"children":[
			{
				"name":"ETA_09930 era; GTP-binding protein\tK03595 era; GTPase"
			},
			{
				"name":"ETA_03340 Putative GTP-binding protein\tK03979 obgE; GTPase [EC:3.6.5.-]"
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic type",
		"children":[
		{
			"name":"Sno RNPs",
			"children":[
			{
				"name":"Box C\/D snoRNPs"
			},
			{
				"name":"Box H\/ACA snoRNPs"
			}
			]
		},
		{
			"name":"rRNA transcription factors",
			"children":[
			{
				"name":"ETA_08610 dksA; DnaK suppressor protein (DnaK suppressor protein homologue)\tK06204 dksA; RNA polymerase-binding transcription factor"
			},
			{
				"name":"ETA_03460 nusA; Transcription elongation protein NusA (N utilization substance protein A)\tK02600 nusA; transcription termination\/antitermination protein NusA"
			},
			{
				"name":"ETA_25300 nusB; N utilization substance protein B\tK03625 nusB; transcription antitermination protein NusB"
			},
			{
				"name":"ETA_01500 nusG; Transcription antitermination protein\tK02601 nusG; transcription termination\/antitermination protein NusG"
			}
			]
		},
		{
			"name":"rRNA modification factors",
			"children":[
			{
				"name":"16S rRNA modification factors",
				"children":[
				{
					"name":"ETA_12620 rsuA; Ribosomal small subunit pseudouridine synthase A\tK06183 rsuA; 16S rRNA pseudouridine516 synthase [EC:5.4.99.19]"
				},
				{
					"name":"ETA_07240 ksgA; Dimethyladenosine transferase\tK02528 ksgA; 16S rRNA (adenine1518-N6\/adenine1519-N6)-dimethyltransferase [EC:2.1.1.182]"
				},
				{
					"name":"ETA_31300 sun; rRNA methylase Sun\tK03500 rsmB; 16S rRNA (cytosine967-C5)-methyltransferase [EC:2.1.1.176]"
				},
				{
					"name":"ETA_06060 yjjT; Ribosomal RNA small subunit methyltransferase C\tK00564 rsmC; 16S rRNA (guanine1207-N2)-methyltransferase [EC:2.1.1.172]"
				},
				{
					"name":"ETA_32780 yhhF; Putative methylase YhhF\tK08316 rsmD; 16S rRNA (guanine966-N2)-methyltransferase [EC:2.1.1.171]"
				},
				{
					"name":"ETA_28300 yggJ; Conserved hypothetical protein YggJ\tK09761 rsmE; 16S rRNA (uracil1498-N3)-methyltransferase [EC:2.1.1.193]"
				},
				{
					"name":"ETA_15110 yebU; Conserved hypothetical protein YebU\tK11392 rsmF; 16S rRNA (cytosine1407-C5)-methyltransferase [EC:2.1.1.178]"
				},
				{
					"name":"ETA_34830 gidB; Methyltransferase GidB (Glucose-inhibited division protein B)\tK03501 gidB; 16S rRNA (guanine527-N7)-methyltransferase [EC:2.1.1.170]"
				},
				{
					"name":"ETA_07470 mraW; S-adenosyl-methyltransferase MraW\tK03438 mraW; 16S rRNA (cytosine1402-N4)-methyltransferase [EC:2.1.1.199]"
				},
				{
					"name":"ETA_29190 Putative tetrapyrrole methylase\tK07056 rsmI; 16S rRNA (cytidine1402-2'-O)-methyltransferase [EC:2.1.1.198]"
				},
				{
					"name":"ETA_33210 yhiQ; Conserved hypothetical protein YhiQ\tK15984 rsmJ; 16S rRNA (guanine1516-N2)-methyltransferase [EC:2.1.1.242]"
				}
				]
			},
			{
				"name":"23S rRNA modification factors",
				"children":[
				{
					"name":"ETA_15230 rrmA; Ribosomal RNA large subunit methyltransferase A\tK00563 rlmA1; 23S rRNA (guanine745-N1)-methyltransferase [EC:2.1.1.187]"
				},
				{
					"name":"ETA_29590 rlmB; 23S rRNA (guanosine-2'-O-)-methyltransferase\tK03218 rlmB; 23S rRNA (guanosine2251-2'-O)-methyltransferase [EC:2.1.1.185]"
				},
				{
					"name":"ETA_03400 rrmJ; Ribosomal RNA large subunit methyltransferase\tK02427 rlmE; 23S rRNA (uridine2552-2'-O)-methyltransferase [EC:2.1.1.166]"
				},
				{
					"name":"ETA_22110 Conserved hypothetical protein (DUF890)\tK06970 rlmF; 23S rRNA (adenine1618-N6)-methyltransferase [EC:2.1.1.181]"
				},
				{
					"name":"ETA_28960 rsmD; Putative ribosomal RNA small subunit methyltransferase D\tK11391 rlmG; 23S rRNA (guanine1835-N2)-methyltransferase [EC:2.1.1.174]"
				},
				{
					"name":"ETA_23520 Conserved hypothetical protein (DUF163)\tK00783 rlmH; 23S rRNA (pseudouridine1915-N3)-methyltransferase [EC:2.1.1.177]"
				},
				{
					"name":"ETA_20930 SAM-dependent methyltransferase\tK06969 rlmI; 23S rRNA (cytosine1962-C5)-methyltransferase [EC:2.1.1.191]"
				},
				{
					"name":"ETA_33240 yhiR; Conserved hypothetical protein YhiR\tK07115 rlmJ; 23S rRNA (adenine2030-N6)-methyltransferase [EC:2.1.1.266]"
				},
				{
					"name":"ETA_21120 ycbY; Conserved hypothetical protein YcbY\tK12297 rlmKL; 23S rRNA (guanine2069-N7)-methyltransferase \/ 23S rRNA (guanine2445-N2)-methyltransferase [EC:2.1.1.264 2.1.1.173]"
				},
				{
					"name":"ETA_27340 mtfA; Putative RNA 2'-O-ribose methyltransferase\tK06968 rlmM; 23S rRNA (cytidine2498-2'-O)-methyltransferase [EC:2.1.1.186]"
				},
				{
					"name":"ETA_10250 yfgB; Conserved hypothetical protein YfgB\tK06941 rlmN; 23S rRNA (adenine2503-C2)-methyltransferase [EC:2.1.1.192]"
				},
				{
					"name":"ETA_27240 rumA; 23S rRNA (uracil-5-)-methyltransferase\tK03215 rumA; 23S rRNA (uracil1939-C5)-methyltransferase [EC:2.1.1.190]"
				},
				{
					"name":"ETA_07290 rluA; Ribosomal large subunit pseudouridine synthase A\tK06177 rluA; tRNA pseudouridine32 synthase \/ 23S rRNA pseudouridine746 synthase [EC:5.4.99.28 5.4.99.29]"
				},
				{
					"name":"ETA_10430 Pseudouridylate synthase\tK06177 rluA; tRNA pseudouridine32 synthase \/ 23S rRNA pseudouridine746 synthase [EC:5.4.99.28 5.4.99.29]"
				},
				{
					"name":"ETA_16100 rluB; Ribosomal large subunit pseudouridine synthase B\tK06178 rluB; 23S rRNA pseudouridine2605 synthase [EC:5.4.99.22]"
				},
				{
					"name":"ETA_20290 rluC; 23S rRNA pseudouridylate synthase\tK06179 rluC; 23S rRNA pseudouridine955\/2504\/2580 synthase [EC:5.4.99.24]"
				},
				{
					"name":"ETA_26440 rluD; Ribosomal large subunit pseudouridine synthase D\tK06180 rluD; 23S rRNA pseudouridine1911\/1915\/1917 synthase [EC:5.4.99.23]"
				},
				{
					"name":"ETA_19500 rluE; Ribosomal large subunit pseudouridine synthase E\tK06181 rluE; 23S rRNA pseudouridine2457 synthase [EC:5.4.99.20]"
				},
				{
					"name":"ETA_00360 rluF; Ribosomal large subunit pseudouridine synthase F\tK06182 rluF; 23S rRNA pseudouridine2604 synthase [EC:5.4.99.21]"
				},
				{
					"name":"ETA_09280 spoU; Predicted tRNA\/rRNA methyltransferase\tK03214 yfiF; RNA methyltransferase, TrmH family [EC:2.1.1.-]"
				}
				]
			}
			]
		},
		{
			"name":"ribosomal protein modification factors",
			"children":[
			{
				"name":"ETA_06080 rimI; Ribosomal-protein-alanine acetyltransferase\tK03789 rimI; [ribosomal protein S18]-alanine N-acetyltransferase \/ [ribosomal protein L31]-L-lysine N-acetyltransferase [EC:2.3.1.266 2.3.1.338]"
			},
			{
				"name":"ETA_20490 rimJ; Ribosomal-protein-alanine acetyltransferase\tK03790 rimJ; [ribosomal protein S5]-alanine N-acetyltransferase [EC:2.3.1.267]"
			},
			{
				"name":"ETA_26500 Probable ribosomal-protein-serine acetyltransferase\tK03817 rimL; ribosomal-protein-serine acetyltransferase [EC:2.3.1.-]"
			},
			{
				"name":"ETA_26560 rimM; 16S rRNA-processing protein RimM\tK02860 rimM; 16S rRNA processing protein RimM"
			},
			{
				"name":"ETA_21460 ycaO; Conserved hypothetical protein YcaO\tK09136 ycaO; ribosomal protein S12 methylthiotransferase accessory factor"
			},
			{
				"name":"ETA_02740 prmA; Ribosomal protein L11 methyltransferase\tK02687 prmA; ribosomal protein L11 methyltransferase [EC:2.1.1.-]"
			},
			{
				"name":"ETA_11530 yfcB; Probable adenine-specific methylase\tK07320 prmB; ribosomal protein L3 glutamine methyltransferase [EC:2.1.1.298]"
			},
			{
				"name":"ETA_19720 ycfD; Conserved hypothetical protein YcfD\tK18850 ycfD; 50S ribosomal protein L16 3-hydroxylase [EC:1.14.11.47]"
			}
			]
		},
		{
			"name":"rRNA processing factors",
			"children":[
			{
				"name":"ETA_09920 rnc; Ribonuclease III\tK03685 rnc; ribonuclease III [EC:3.1.26.3]"
			},
			{
				"name":"ETA_20300 ams; Ribonuclease E\tK08300 rne; ribonuclease E [EC:3.1.26.12]"
			},
			{
				"name":"ETA_02880 cafA; Ribonuclease G\tK08301 rng; ribonuclease G [EC:3.1.26.-]"
			},
			{
				"name":"ETA_28330 yqgF; Putative Holliday junction resolvase\tK07447 ruvX; putative pre-16S rRNA nuclease [EC:3.1.-.-]"
			}
			]
		},
		{
			"name":"rRNA helicases",
			"children":[
			{
				"name":"ETA_16560 ATP-dependent RNA helicase\tK05591 dbpA; ATP-dependent RNA helicase DbpA [EC:5.6.2.6]"
			},
			{
				"name":"ETA_03530 deaD; Cold-shock DEAD-box protein A\tK05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7]"
			},
			{
				"name":"ETA_09810 ATP-dependent RNA helicase\tK05590 srmB; ATP-dependent RNA helicase SrmB [EC:5.6.2.7]"
			}
			]
		},
		{
			"name":"GTPases",
			"children":[
			{
				"name":"ETA_09930 era; GTP-binding protein\tK03595 era; GTPase"
			},
			{
				"name":"ETA_29740 engC; Probable GTPase EngC\tK06949 rsgA; ribosome biogenesis GTPase \/ thiamine phosphate phosphatase [EC:3.6.1.- 3.1.3.100]"
			},
			{
				"name":"ETA_10320 engA; GTP-binding protein\tK03977 engA; GTPase"
			},
			{
				"name":"ETA_03340 Putative GTP-binding protein\tK03979 obgE; GTPase [EC:3.6.5.-]"
			},
			{
				"name":"ETA_29660 hflX; GTP-binding protein HflX\tK03665 hflX; GTPase"
			}
			]
		},
		{
			"name":"Other maturation factors",
			"children":[
			{
				"name":"ETA_00410 spoT; Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase\tK01139 spoT; GTP diphosphokinase \/ guanosine-3',5'-bis(diphosphate) 3'-diphosphatase [EC:2.7.6.5 3.1.7.2]"
			},
			{
				"name":"ETA_03480 rbfA; Ribosome-binding factor A\tK02834 rbfA; ribosome-binding factor A"
			},
			{
				"name":"ETA_03450 YhbC-like protein\tK09748 rimP; ribosome maturation factor RimP"
			},
			{
				"name":"ETA_24350 Conserved hypothetical protein\tK14761 rlbA; ribosome-associated protein"
			},
			{
				"name":"ETA_23510 ybeB; Conserved hHypothetical protein YbeB\tK09710 ybeB; ribosome-associated protein"
			},
			{
				"name":"ETA_23390 ybeY; Conserved hypothetical protein (UPF0054)\tK07042 ybeY; probable rRNA maturation factor"
			},
			{
				"name":"ETA_03390 yhbY; Predicted RNA-binding protein containing KH domain, possibly ribosomal protein\tK07574 yhbY; RNA-binding protein"
			},
			{
				"name":"ETA_34210 Conserved hypothetical protein\tK14762 yibL; ribosome-associated protein"
			},
			{
				"name":"ETA_29350 Conserved hypothetical protein\tK09889 yjgA; ribosome-associated protein"
			},
			{
				"name":"ETA_03140 yhbH; sigma 54 modulation protein\/S30EA ribosomal protein\tK05808 hpf; ribosome hibernation promoting factor"
			},
			{
				"name":"ETA_26460 yfiA; Ribosome associated factor, stabilizes ribosomes against dissociation\tK05809 raiA; ribosome-associated inhibitor A"
			},
			{
				"name":"ETA_18870 engD; Putative GTP-binding protein\tK06942 ychF; ribosome-binding ATPase"
			},
			{
				"name":"ETA_20270 yceD; Conserved hypothetical protein YceD\tK07040 yceD; DUF177 domain-containing protein"
			}
			]
		}
		]
	},
	{
		"name":"Related small nucleolar RNAs",
		"children":[
		{
			"name":"Box C\/D snoRNAs",
			"children":[
			{
				"name":"SnoRNAs involved in processing reactions"
			},
			{
				"name":"SnoRNAs act as guides for 2'-O-ribose methylation"
			}
			]
		},
		{
			"name":"Box H\/ACA snoRNAs",
			"children":[
			{
				"name":"SnoRNAs involved in processing reactions"
			},
			{
				"name":"SnoRNAs act as guides for pseudouridynation"
			}
			]
		},
		{
			"name":"Other snoRNA"
		}
		]
	}
	]
}
