{
	"name":"eum03000",
	"children":[
	{
		"name":"Eukaryotic type",
		"children":[
		{
			"name":"Basic leucine zipper (bZIP)",
			"children":[
			{
				"name":"AP-1(-like) components, Jun"
			},
			{
				"name":"AP-1(-like) components, Fos"
			},
			{
				"name":"AP-1(-like) components, Maf"
			},
			{
				"name":"AP-1(-like) components, NF-E2"
			},
			{
				"name":"AP-1(-like) components, Fungal regulators"
			},
			{
				"name":"AP-1(-like) components, CRE-BP\/ATF"
			},
			{
				"name":"CREB"
			},
			{
				"name":"C\/EBP-like factors"
			},
			{
				"name":"bZIP\/PAR"
			},
			{
				"name":"Plant bZIP factors"
			},
			{
				"name":"ZIP only"
			}
			]
		},
		{
			"name":"Basic helix-loop-helix (bHLH)",
			"children":[
			{
				"name":"Ubiquitous (class A) factors"
			},
			{
				"name":"Myogenic transcription factors"
			},
			{
				"name":"Achaete-Scute"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, Lymphoid factors"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, Mesodermal Twist-like factors"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, HEN"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, Mesp"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, Atonal"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, Pancreatic factors"
			},
			{
				"name":"Hairy, Hairy\/E(SPL)"
			},
			{
				"name":"Hairy, Fungal regulators"
			},
			{
				"name":"Factors with PAS domain"
			},
			{
				"name":"Yabby"
			},
			{
				"name":"INO"
			},
			{
				"name":"HLH domain only"
			}
			]
		},
		{
			"name":"Basic helix-loop-helix\/leucine zipper (bHLH-ZIP)",
			"children":[
			{
				"name":"Ubiquitous bHLH-ZIP factors"
			},
			{
				"name":"Cell cycle controlling factors, Myc"
			},
			{
				"name":"Cell cycle controlling factors, Mad\/Max"
			},
			{
				"name":"Other bHLH-ZIP factors"
			}
			]
		},
		{
			"name":"Other basic domains",
			"children":[
			{
				"name":"NF-1"
			},
			{
				"name":"RF-X"
			},
			{
				"name":"AP-2 (bHSH)"
			}
			]
		},
		{
			"name":"Zinc finger",
			"children":[
			{
				"name":"Cys4 thyroid hormone receptor-like"
			},
			{
				"name":"Cys4 hepatocyte nuclear factor 4-like"
			},
			{
				"name":"Cys4 estrogen receptor-like"
			},
			{
				"name":"Cys4 nerve growth factor IB-like"
			},
			{
				"name":"Cys4 Fushi tarazu-F1-like"
			},
			{
				"name":"Cys4 germ cell nuclear factor"
			},
			{
				"name":"Cys4 Knirps\/DAX1-like"
			},
			{
				"name":"Cys4 GATA-factors"
			},
			{
				"name":"Cys2His2 SP\/KLF family and related proteins"
			},
			{
				"name":"Cys2His2 GLI-like"
			},
			{
				"name":"Cys2His2 Snail"
			},
			{
				"name":"Cys2His2 BTB-ZF factors"
			},
			{
				"name":"Cys2His2 BED"
			},
			{
				"name":"Cys2His2 PRDM"
			},
			{
				"name":"Cys2His2 metabolic regulators in fungi"
			},
			{
				"name":"Cys2His2 others"
			},
			{
				"name":"Cys2HisCys zinc factors"
			},
			{
				"name":"Cys3His zinc factors"
			},
			{
				"name":"Cys2CysHis zinc factors"
			},
			{
				"name":"CXXC CpG-binding proteins",
				"children":[
				{
					"name":"ECUMN_2253 dcm; DNA cytosine methylase\tK00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]"
				}
				]
			},
			{
				"name":"Cys6 metabolic regulators in fungi"
			},
			{
				"name":"Other zinc fingers"
			}
			]
		},
		{
			"name":"Helix-turn-helix",
			"children":[
			{
				"name":"Homeo domain ANTP: HOXL"
			},
			{
				"name":"Homeo domain ANTP: NKL"
			},
			{
				"name":"Homeo domain Paired-related"
			},
			{
				"name":"Homeo domain LIM"
			},
			{
				"name":"Homeo domain POU"
			},
			{
				"name":"Homeo domain SINE"
			},
			{
				"name":"Homeo domain ZF"
			},
			{
				"name":"Homeo domain CUT"
			},
			{
				"name":"Homeo domain PROS"
			},
			{
				"name":"Homeo domain TALE"
			},
			{
				"name":"Homeo domain other"
			},
			{
				"name":"Fork head\/winged helix developmental regulators"
			},
			{
				"name":"Fork head\/winged helix tissue-specific regulators"
			},
			{
				"name":"Fork head\/winged helix cell cycle-controlling factors, E2F"
			},
			{
				"name":"Fork head\/winged helix cell cycle-controlling factors, DP"
			},
			{
				"name":"Fork head\/winged helix other regulators"
			},
			{
				"name":"Stork head\/winged helix factors"
			},
			{
				"name":"Heat shock factors"
			},
			{
				"name":"Tryptophan clusters Myb, Myb-factors"
			},
			{
				"name":"Tryptophan clusters Myb, Myb-like factors"
			},
			{
				"name":"Tryptophan clusters Ets-type"
			},
			{
				"name":"Tryptophan clusters interferon-regulating factors"
			},
			{
				"name":"TEA domain"
			},
			{
				"name":"ARID"
			}
			]
		},
		{
			"name":"beta-Scaffold factors with minor groove contacts",
			"children":[
			{
				"name":"RHR (Rel homology region) Rel\/Ankyrin"
			},
			{
				"name":"RHR (Rel homology region) Ankyrin only"
			},
			{
				"name":"RHR (Rel homology region) NF-AT"
			},
			{
				"name":"STAT"
			},
			{
				"name":"p53"
			},
			{
				"name":"MADS-box regulators of differentiation, MEF-2"
			},
			{
				"name":"MADS-box regulators of differentiation, Homeotic genes"
			},
			{
				"name":"MADS-box regulators of differentiation, Yeast regulators"
			},
			{
				"name":"MADS-box responders to external signals"
			},
			{
				"name":"SAND domain-containing proteins"
			},
			{
				"name":"TATA-binding proteins"
			},
			{
				"name":"HMG SOX"
			},
			{
				"name":"HMG TCF-1"
			},
			{
				"name":"HMG TOX"
			},
			{
				"name":"HMG2-related"
			},
			{
				"name":"UBF"
			},
			{
				"name":"Other HMG box factors"
			},
			{
				"name":"Heteromeric CCAAT factors"
			},
			{
				"name":"Grainyhead"
			},
			{
				"name":"Cold-shock domain factors, DbpA-like"
			},
			{
				"name":"Cold-shock domain factors, YB-1\/DbpB-like"
			},
			{
				"name":"Cold-shock domain factors, FRG Y2-like"
			},
			{
				"name":"Runt"
			},
			{
				"name":"MYRF"
			}
			]
		},
		{
			"name":"Other transcription factors",
			"children":[
			{
				"name":"HMGI(Y)"
			},
			{
				"name":"NUPR"
			},
			{
				"name":"Pocket domain Rb"
			},
			{
				"name":"Pocket domain CBP"
			},
			{
				"name":"T-box"
			},
			{
				"name":"DMRT"
			},
			{
				"name":"LRRFIP"
			},
			{
				"name":"TCP"
			},
			{
				"name":"AP2\/ERF"
			},
			{
				"name":"WRKY"
			},
			{
				"name":"LOB"
			},
			{
				"name":"GRAS"
			},
			{
				"name":"NAC"
			},
			{
				"name":"Copper-fist proteins fungal regulators"
			},
			{
				"name":"Others"
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic type",
		"children":[
		{
			"name":"Helix-turn-helix",
			"children":[
			{
				"name":"AraC family",
				"children":[
				{
					"name":"ECUMN_0065 araC; DNA-binding transcriptional dual regulator\tK02099 araC; AraC family transcriptional regulator, arabinose operon regulatory protein"
				},
				{
					"name":"ECUMN_4967 hpaA; Regulator of the 4HPA-hydroxylase operon\tK02508 hpaA; AraC family transcriptional regulator, 4-hydroxyphenylacetate 3-monooxygenase operon regulatory protein"
				},
				{
					"name":"ECUMN_4435 rhaR; DNA-binding transcriptional activator, L-rhamnose-binding\tK02854 rhaR; AraC family transcriptional regulator, L-rhamnose operon transcriptional activator RhaR"
				},
				{
					"name":"ECUMN_4434 rhaS; DNA-binding transcriptional activator, L-rhamnose-binding\tK02855 rhaS; AraC family transcriptional regulator, L-rhamnose operon regulatory protein RhaS"
				},
				{
					"name":"ECUMN_2024 chbR; DNA-binding transcriptional dual regulator\tK03490 chbR; AraC family transcriptional regulator, dual regulator of chb operon"
				},
				{
					"name":"ECUMN_4648 adiY; DNA-binding transcriptional activator\tK03755 adiY; AraC family transcriptional regulator, transcriptional activator of adiA"
				},
				{
					"name":"ECUMN_2758 yfeG; putative DNA-binding transcriptional regulator\tK04033 eutR; AraC family transcriptional regulator, ethanolamine operon transcriptional activator"
				},
				{
					"name":"ECUMN_2272 ybtA; AraC type regulator of yersiniabactin gene cluster (HPI)\tK05372 ybtA; AraC family transcriptional regulator"
				},
				{
					"name":"ECUMN_0636 appY; DNA-binding transcriptional activator; DLP12 prophage\tK07780 appY; AraC family transcriptional regulator, transcriptional regulator required for anaerobic and stationary phase induction of genes"
				},
				{
					"name":"ECUMN_0639 envY; DNA-binding transcriptional activator of porin biosynthesis\tK11920 envY; AraC family transcriptional regulator"
				},
				{
					"name":"ECUMN_4598 soxS; DNA-binding transcriptional dual regulator\tK13631 soxS; AraC family transcriptional regulator, mar-sox-rob regulon activator"
				},
				{
					"name":"ECUMN_1799 marA; DNA-binding transcriptional dual activator of multiple antibiotic resistance\tK13632 marA; AraC family transcriptional regulator, mar-sox-rob regulon activator"
				},
				{
					"name":"ECUMN_5027 rob; DNA-binding transcriptional activator\tK05804 rob; AraC family transcriptional regulator, mar-sox-rob regulon activator"
				},
				{
					"name":"ECUMN_p10052 tetD; putative transcriptionnal regulator involved in tetracycline resistance\tK19056 tetD; AraC family transcriptional regulator, transposon Tn10 TetD protein"
				},
				{
					"name":"ECUMN_0343 ykgD; putative AraC-type DNA-binding transcriptional regulator\tK21746 rclR; AraC family transcriptional regulator, reactive chlorine species (RCS)-specific activator of rcl operon"
				},
				{
					"name":"ECUMN_1409 putative araC-type regulatory protein from bacteriophage origin\tK21906 gadW; AraC family transcriptional regulator, glutamate-dependent acid resistance regulator"
				},
				{
					"name":"ECUMN_4016 gadW; DNA-binding transcriptional activator\tK21906 gadW; AraC family transcriptional regulator, glutamate-dependent acid resistance regulator"
				},
				{
					"name":"ECUMN_4017 gadX; DNA-binding transcriptional dual regulator\tK21905 gadX; AraC family transcriptional regulator, glutamate-dependent acid resistance regulator"
				},
				{
					"name":"ECUMN_4650 melR; DNA-binding transcriptional dual regulator\tK23237 melR; AraC family transcriptional regulator, melibiose operon regulatory protein"
				},
				{
					"name":"ECUMN_2079 yeaM; putative DNA-binding transcriptional regulator\tK25495 nimR; AraC family transcriptional regulator, regulator of nimT"
				},
				{
					"name":"ECUMN_2332 pocR; Propanediol utilization: transcriptional regulation\tK27259 pocR; AraC family transcriptional regulator, pdu and cob operon regulator"
				},
				{
					"name":"ECUMN_2549 ada; fused DNA-binding transcriptional dual regulator; O6-methylguanine-DNA methyltransferase\tK10778 ada; AraC family transcriptional regulator, regulatory protein of adaptative response \/ methylated-DNA-[protein]-cysteine methyltransferase [EC:2.1.1.63]"
				}
				]
			},
			{
				"name":"LysR family",
				"children":[
				{
					"name":"ECUMN_3137 gcvA; DNA-binding transcriptional dual regulator\tK03566 gcvA; LysR family transcriptional regulator, glycine cleavage system transcriptional activator"
				},
				{
					"name":"ECUMN_4299 ilvY; DNA-binding transcriptional dual regulator\tK02521 ilvY; LysR family transcriptional regulator, positive regulator for ilvC"
				},
				{
					"name":"ECUMN_4354 metR; DNA-binding transcriptional activator, homocysteine-binding\tK03576 metR; LysR family transcriptional regulator, regulator for metE and metH"
				},
				{
					"name":"ECUMN_0017 nhaR; DNA-binding transcriptional activator\tK03717 nhaR; LysR family transcriptional regulator, transcriptional activator of nhaA"
				},
				{
					"name":"ECUMN_4492 oxyR; DNA-binding transcriptional dual regulator\tK04761 oxyR; LysR family transcriptional regulator, hydrogen peroxide-inducible genes activator"
				},
				{
					"name":"ECUMN_3260 argP; DNA-binding transcriptional activator, replication initiation inhibitor\tK05596 argP; LysR family transcriptional regulator, arginine and lysine transport system\/DNA replication regulator"
				},
				{
					"name":"ECUMN_0077 leuO; DNA-binding transcriptional activator\tK05798 leuO; LysR family transcriptional regulator, transcriptional activator for leuABCD operon"
				},
				{
					"name":"ECUMN_2857 hcaR; DNA-binding transcriptional activator of 3-phenylpropionic acid catabolism\tK05817 hcaR; LysR family transcriptional regulator, hca operon transcriptional activator"
				},
				{
					"name":"ECUMN_3602 tdcA; DNA-binding transcriptional activator\tK07592 tdcA; LysR family transcriptional regulator, tdc operon transcriptional activator"
				},
				{
					"name":"ECUMN_0545 ybbS; putative DNA-binding transcriptional activator of the allD operon\tK10972 allS; LysR family transcriptional regulator, transcriptional activator of the allD operon"
				},
				{
					"name":"ECUMN_0381 cynR; DNA-binding transcriptional dual regulator\tK11921 cynR; LysR family transcriptional regulator, cyn operon transcriptional activator"
				},
				{
					"name":"ECUMN_1574 cysB; DNA-binding transcriptional dual regulator, O-acetyl-L-serine-binding\tK13634 cysB; LysR family transcriptional regulator, cys regulon transcriptional activator"
				},
				{
					"name":"ECUMN_2324 cbl; DNA-binding transcriptional activator of cysteine biosynthesis\tK13635 cbl; LysR family transcriptional regulator, cys regulon transcriptional activator"
				},
				{
					"name":"ECUMN_1635 abgR; DNA-binding transcriptional regulator\tK14057 abgR; LysR family transcriptional regulator, regulator of abg operon"
				},
				{
					"name":"ECUMN_2089 yeaT; putative DNA-binding transcriptional regulator\tK16135 dmlR; LysR family transcriptional regulator, transcriptional activator for dmlA"
				},
				{
					"name":"ECUMN_2325 nac; DNA-binding transcriptional dual regulator of nitrogen assimilation\tK19338 nac; LysR family transcriptional regulator, nitrogen assimilation regulatory protein"
				},
				{
					"name":"ECUMN_4936 yjiE; putative DNA-binding transcriptional regulator\tK21645 hypT; LysR family transcriptional regulator, hypochlorite-specific transcription factor HypT"
				},
				{
					"name":"ECUMN_3717 aaeR; DNA-binding transcriptional regulator, efflux system\tK21698 aaeR; LysR family transcriptional regulator, transcriptional activator for aaeXAB operon"
				},
				{
					"name":"ECUMN_3543 ygiP; putative DNA-binding transcriptional regulator\tK21742 ttdR; LysR family transcriptional regulator, transcriptional activator for ttdABT operon"
				},
				{
					"name":"ECUMN_4291 hdfR; DNA-binding transcriptional regulator\tK23773 hdfR; LysR family transcriptional regulator, flagellar master operon regulator"
				},
				{
					"name":"ECUMN_1624 ycjZ; putative nucleic acid-binding regulator\tK24082 pgrR; LysR family transcriptional regulator, regulator of peptidoglycan recycling"
				}
				]
			},
			{
				"name":"DeoR family",
				"children":[
				{
					"name":"ECUMN_1030 deoR; DNA-binding transcriptional repressor\tK11534 deoR; DeoR family transcriptional regulator, deoxyribose operon repressor"
				},
				{
					"name":"ECUMN_3881 glpR; DNA-binding transcriptional repressor\tK02444 glpR; DeoR family transcriptional regulator, glycerol-3-phosphate regulon repressor"
				},
				{
					"name":"ECUMN_2422 gatR; Galactitol utilization operon repressor\tK02436 gatR; DeoR family transcriptional regulator, galactitol utilization operon repressor"
				},
				{
					"name":"ECUMN_3613 agaR; DNA-binding transcriptional dual regulator\tK02081 agaR; DeoR family transcriptional regulator, aga operon transcriptional repressor"
				},
				{
					"name":"ECUMN_3134 fucR; DNA-binding transcriptional activator\tK02430 fucR; DeoR family transcriptional regulator, L-fucose operon activator"
				},
				{
					"name":"ECUMN_3028 srlR; DNA-bindng transcriptional repressor\tK02468 srlR; DeoR family transcriptional regulator, glucitol operon repressor"
				},
				{
					"name":"ECUMN_4724 ulaR; DNA-binding transcriptional dual regulator\tK03477 ulaR; DeoR family transcriptional regulator, ulaG and ulaABCDEF operon transcriptional repressor"
				},
				{
					"name":"ECUMN_4411 yihW; putative DNA-binding transcriptional regulator\tK27243 csqR; DeoR family transcriptional regulator, sulfoquinovose operon repressor"
				}
				]
			},
			{
				"name":"LacI family",
				"children":[
				{
					"name":"ECUMN_0388 lacI; DNA-binding transcriptional repressor\tK27069 lacI; LacI family transcriptional regulator, lactose operon repressor"
				},
				{
					"name":"ECUMN_2484 galS; DNA-binding transcriptional repressor\tK02529 galR; LacI family transcriptional regulator, galactose operon repressor"
				},
				{
					"name":"ECUMN_3165 galR; DNA-binding transcriptional repressor\tK02529 galR; LacI family transcriptional regulator, galactose operon repressor"
				},
				{
					"name":"ECUMN_4081 xylR; DNA-binding transcriptional activator, xylose-binding\tK02529 galR; LacI family transcriptional regulator, galactose operon repressor"
				},
				{
					"name":"ECUMN_4283 rbsR; DNA-binding transcriptional repressor of ribose metabolism\tK02529 galR; LacI family transcriptional regulator, galactose operon repressor"
				},
				{
					"name":"ECUMN_4464 cytR; DNA-binding transcriptional dual regulator\tK05499 cytR; LacI family transcriptional regulator, repressor for deo operon, udp, cdd, tsx, nupC, and nupG"
				},
				{
					"name":"ECUMN_0080 fruR; DNA-binding transcriptional dual regulator\tK03435 fruR1; LacI family transcriptional regulator, fructose operon transcriptional repressor"
				},
				{
					"name":"ECUMN_4774 treR; DNA-binding transcriptional repressor\tK03485 treR; LacI family transcriptional regulator, trehalose operon repressor"
				},
				{
					"name":"ECUMN_3036 ascG; DNA-binding transcriptional repressor\tK03487 ascG; LacI family transcriptional regulator, asc operon repressor"
				},
				{
					"name":"ECUMN_1948 purR; DNA-binding transcriptional repressor, hypoxanthine-binding\tK03604 purR; LacI family transcriptional regulator, purine nucleotide synthesis repressor"
				},
				{
					"name":"ECUMN_3901 gntR; DNA-binding transcriptional repressor\tK06145 gntR; LacI family transcriptional regulator, gluconate utilization system Gnt-I transcriptional repressor"
				},
				{
					"name":"ECUMN_4796 idnR; DNA-binding transcriptional repressor, 5-gluconate-binding\tK06146 idnR; LacI family transcriptional regulator, gluconate utilization system Gnt-II transcriptional activator"
				},
				{
					"name":"ECUMN_3558 ebgR; DNA-binding transcriptional repressor\tK12113 ebgR; LacI family transcriptional regulator, ebg operon repressor"
				},
				{
					"name":"ECUMN_1910 malI; DNA-binding transcriptional repressor\tK16136 malI; LacI family transcriptional regulator, maltose regulon regulatory protein"
				}
				]
			},
			{
				"name":"GntR family",
				"children":[
				{
					"name":"ECUMN_4215 yidP; putative DNA-binding transcriptional regulator\tK03482 yidP; GntR family transcriptional regulator, glv operon transcriptional regulator"
				},
				{
					"name":"ECUMN_4634 phnF; putative DNA-binding transcriptional regulator of phosphonate uptake and biodegradation\tK02043 phnF; GntR family transcriptional regulator, phosphonate transport system regulatory protein"
				},
				{
					"name":"ECUMN_1476 fadR; DNA-binding transcriptional dual regulator of fatty acid metabolism\tK03603 fadR; GntR family transcriptional regulator, negative regulator for fad regulon and positive regulator of fabA"
				},
				{
					"name":"ECUMN_0110 pdhR; DNA-binding transcriptional dual regulator\tK05799 pdhR; GntR family transcriptional regulator, transcriptional repressor for pyruvate dehydrogenase complex"
				},
				{
					"name":"ECUMN_3456 glcC; DNA-binding transcriptional dual regulator, glycolate-binding\tK11474 glcC; GntR family transcriptional regulator, glc operon transcriptional activator"
				},
				{
					"name":"ECUMN_4932 uxuR; DNA-binding transcriptional repressor\tK13637 uxuR; GntR family transcriptional regulator, uxu operon transcriptional repressor"
				},
				{
					"name":"ECUMN_3578 exuR; DNA-binding transcriptional repressor\tK19775 exuR; GntR family transcriptional regulator, hexuronate regulon transcriptional repressor"
				},
				{
					"name":"ECUMN_4119 lldR; DNA-binding transcriptional repressor\tK14348 lldR; GntR family transcriptional regulator, L-lactate dehydrogenase operon regulator"
				},
				{
					"name":"ECUMN_4226 dgoR; putative DNA-binding transcriptional regulator\tK19776 dgoR; GntR family transcriptional regulator, galactonate operon transcriptional repressor"
				},
				{
					"name":"ECUMN_3378 nanR; Transcriptional regulator\tK22104 nanR; GntR family transcriptional regulator, sialic acid-inducible nan operon repressor"
				},
				{
					"name":"ECUMN_3700 nanR; DNA-binding transcriptional dual regulator\tK22104 nanR; GntR family transcriptional regulator, sialic acid-inducible nan operon repressor"
				},
				{
					"name":"ECUMN_2997 putative fused protein: aminotransaminase\/transcriptional regulator, GntR family\tK00375 K00375; GntR family transcriptional regulator \/ MocR family aminotransferase"
				},
				{
					"name":"ECUMN_1699 yncC; putative DNA-binding transcriptional regulator\tK13654 mcbR; GntR family transcriptional regulator, colanic acid and biofilm gene transcriptional regulator"
				},
				{
					"name":"ECUMN_2988 csiR; DNA-binding transcriptional dual regulator\tK15735 csiR; GntR family transcriptional regulator, carbon starvation induced regulator"
				},
				{
					"name":"ECUMN_1807 ydfH; putative DNA-binding transcriptional regulator\tK22293 rspR; GntR family transcriptional regulator, rspAB operon transcriptional repressor"
				},
				{
					"name":"ECUMN_4980 yjjM; putative DNA-binding transcriptional regulator\tK23015 lgoR; GntR family transcriptional regulator, transcriptional activator for L-galactonate catabolism"
				}
				]
			},
			{
				"name":"TetR\/AcrR family",
				"children":[
				{
					"name":"ECUMN_p10055 tetR; Tetracycline repressor protein class B from transposon Tn10\tK18476 tetR; TetR\/AcrR family transcriptional regulator, tetracycline repressor protein"
				},
				{
					"name":"ECUMN_p10053 tetC; putative transcriptionnal regulator involved in tetracycline resistance\tK19047 tetC; TetR\/AcrR family transcriptional regulator, repressor of tetCD"
				},
				{
					"name":"ECUMN_0351 betI; DNA-binding transcriptional repressor\tK02167 betI; TetR\/AcrR family transcriptional regulator, transcriptional repressor of bet genes"
				},
				{
					"name":"ECUMN_0503 acrR; DNA-binding transcriptional repressor\tK03577 acrR; TetR\/AcrR family transcriptional regulator, acrAB operon repressor"
				},
				{
					"name":"ECUMN_4156 ttk; division inhibitor\tK05501 slmA; TetR\/AcrR family transcriptional regulator"
				},
				{
					"name":"ECUMN_1196 rutR; DNA-binding transcriptional regulator of the alternative pyrimidine degradation pathway\tK09017 rutR; TetR\/AcrR family transcriptional regulator"
				},
				{
					"name":"ECUMN_1939 ydhM; putative DNA-binding transcriptional regulator\tK16137 nemR; TetR\/AcrR family transcriptional regulator, transcriptional repressor for nem operon"
				},
				{
					"name":"ECUMN_3348 conserved hypothetical protein, putative transcriptional regulator\tK16137 nemR; TetR\/AcrR family transcriptional regulator, transcriptional repressor for nem operon"
				},
				{
					"name":"ECUMN_1907 uidR; DNA-binding transcriptional repressor\tK16138 uidR; TetR\/AcrR family transcriptional regulator, repressor for uid operon"
				},
				{
					"name":"ECUMN_3738 envR; DNA-binding transcriptional regulator\tK18140 envR; TetR\/AcrR family transcriptional regulator, acrEF\/envCD operon repressor"
				},
				{
					"name":"ECUMN_4825 mphR; regulator of macrolide 2'-phosphotransferase I\tK19060 mphR; TetR\/AcrR family transcriptional regulator, macrolide resistance operon repressor"
				},
				{
					"name":"ECUMN_4781 yjgJ; putative transcriptional regulator\tK19335 bdcR; TetR\/AcrR family transcriptional regulator, repressor for divergent bdcA"
				},
				{
					"name":"ECUMN_1289 ycfQ; putative DNA-binding transcriptional regulator\tK22041 comR; TetR\/AcrR family transcriptional regulator, copper-responsive repressor"
				},
				{
					"name":"ECUMN_4494 fabR; DNA-binding transcriptional repressor\tK22105 fabR; TetR\/AcrR family transcriptional regulator, fatty acid biosynthesis regulator"
				},
				{
					"name":"ECUMN_0940 ybiH; putative DNA-binding transcriptional regulator\tK23777 cecR; TetR\/AcrR family transcriptional regulator, regulator of cefoperazone and chloramphenicol sensitivity"
				},
				{
					"name":"ECUMN_1036 ybjK; putative DNA-binding transcriptional regulator\tK23778 rcdA; TetR\/AcrR family transcriptional regulator, regulator of biofilm formation and stress response"
				}
				]
			},
			{
				"name":"Lrp\/AsnC family",
				"children":[
				{
					"name":"ECUMN_4273 asnC; DNA-binding transcriptional dual regulator\tK03718 asnC; Lrp\/AsnC family transcriptional regulator, regulator for asnA, asnC and gidA"
				},
				{
					"name":"ECUMN_1084 lrp; DNA-binding transcriptional dual regulator, leucine-binding\tK03719 lrp; Lrp\/AsnC family transcriptional regulator, leucine-responsive regulatory protein"
				},
				{
					"name":"ECUMN_0487 ybaO; putative DNA-binding transcriptional regulator with homology to Lrp\tK05800 decR; Lrp\/AsnC family transcriptional regulator, cysteine-sensing transcriptional activator"
				}
				]
			},
			{
				"name":"LuxR family",
				"children":[
				{
					"name":"ECUMN_2208 sdiA; DNA-binding transcriptional activator\tK07782 sdiA; LuxR family transcriptional regulator, quorum-sensing system regulator SdiA"
				},
				{
					"name":"ECUMN_0328 ykgK; putative transcriptional regulator\tK21963 ecpR; LuxR family transcriptional regulator, Mat\/Ecp fimbriae transcriptional regulator"
				},
				{
					"name":"ECUMN_2243 rcsA; DNA-binding transcriptional activator, co-regulator with RcsB\tK07781 rcsA; LuxR family transcriptional regulator, capsular biosynthesis positive transcription factor"
				},
				{
					"name":"ECUMN_1214 csgD; DNA-binding transcriptional activator in two-component regulatory system\tK04333 csgD; LuxR family transcriptional regulator, csgAB operon transcriptional regulatory protein"
				},
				{
					"name":"ECUMN_3998 yhiF; putative DNA-binding transcriptional regulator\tK21901 dctR; LuxR family transcriptional regulator, dicarboxylate transport regulator"
				},
				{
					"name":"ECUMN_4989 bglJ; DNA-binding transcriptional activator\tK22650 bglJ; LuxR family transcriptional regulator, regulator of transport and utilization of aryl beta-glucosides"
				},
				{
					"name":"ECUMN_3877 malT; fused conserved hypothetical protein; DNA-binding transcriptional activator, maltotriose-ATP-binding\tK03556 malT; LuxR family transcriptional regulator, maltose regulon positive regulatory protein"
				},
				{
					"name":"ECUMN_4012 gadE; DNA-binding transcriptional activator\tK21907 gadE; LuxR family transcriptional regulator, glutamate-dependent acid resistance regulator"
				}
				]
			},
			{
				"name":"MarR family",
				"children":[
				{
					"name":"ECUMN_1798 marR; DNA-binding transcriptional repressor of multiple antibiotic resistance\tK03712 marR; MarR family transcriptional regulator, multiple antibiotic resistance protein MarR"
				},
				{
					"name":"ECUMN_1933 slyA; DNA-binding transcriptional activator\tK06075 slyA; MarR family transcriptional regulator, transcriptional regulator for hemolysin"
				},
				{
					"name":"ECUMN_3009 mprA; DNA-binding transcriptional repressor of microcin B17 synthesis and multidrug efflux\tK15974 emrR; MarR family transcriptional regulator, negative regulator of the multidrug operon emrRAB"
				},
				{
					"name":"ECUMN_3330 Putative HTH-type transcriptional regulator\tK15974 emrR; MarR family transcriptional regulator, negative regulator of the multidrug operon emrRAB"
				},
				{
					"name":"ECUMN_3063 Transcriptional regulator hosA\tK22489 hosA; MarR family transcriptional regulator, temperature-dependent positive regulator of motility"
				}
				]
			},
			{
				"name":"MerR family",
				"children":[
				{
					"name":"ECUMN_0530 cueR; DNA-binding transcriptional activator of copper-responsive regulon genes\tK19591 cueR; MerR family transcriptional regulator, copper efflux regulator"
				},
				{
					"name":"ECUMN_3766 zntR; DNA-binding transcriptional activator in response to Zn(II)\tK13638 zntR; MerR family transcriptional regulator, Zn(II)-responsive regulator of zntA"
				},
				{
					"name":"ECUMN_4599 soxR; DNA-binding transcriptional dual regulator, Fe-S center for redox-sensing\tK13639 soxR; MerR family transcriptional regulator, redox-sensitive transcriptional activator SoxR"
				},
				{
					"name":"ECUMN_2461 mlrA; DNA-binding transcriptional regulator\tK21089 mlrA; MerR family transcriptional regulator, activator of the csg genes"
				},
				{
					"name":"ECUMN_1447 ycgE; putative DNA-binding transcriptional regulator\tK21972 bluR; MerR family transcriptional regulator, repressor of blue light- and temperature-responsive genes"
				}
				]
			},
			{
				"name":"Fur family",
				"children":[
				{
					"name":"ECUMN_0768 fur; DNA-binding transcriptional dual regulator of siderophore biosynthesis and transport\tK03711 fur; Fur family transcriptional regulator, ferric uptake regulator"
				},
				{
					"name":"ECUMN_4581 zur; DNA-binding transcriptional repressor, Zn(II)-binding\tK09823 zur; Fur family transcriptional regulator, zinc uptake regulator"
				}
				]
			},
			{
				"name":"IclR family",
				"children":[
				{
					"name":"ECUMN_4544 iclR; DNA-binding transcriptional repressor\tK13641 iclR; IclR family transcriptional regulator, acetate operon repressor"
				},
				{
					"name":"ECUMN_0389 mhpR; DNA-binding transcriptional activator, 3HPP-binding\tK05818 mhpR; IclR family transcriptional regulator, mhp operon transcriptional activator"
				},
				{
					"name":"ECUMN_0547 allR; DNA-binding transcriptional repressor\tK10973 allR; IclR family transcriptional regulator, negative regulator of allantoin and glyoxylate utilization operons"
				},
				{
					"name":"ECUMN_2121 kdgR; DNA-binding transcriptional repressor KdgR\tK19333 kdgR; IclR family transcriptional regulator, KDG regulon repressor"
				},
				{
					"name":"ECUMN_4087 yiaJ; DNA-binding transcriptional repressor\tK21602 plaR; IclR family transcriptional regulator, regulator of plant utilization"
				}
				]
			},
			{
				"name":"CRP\/FNR family",
				"children":[
				{
					"name":"ECUMN_3820 crp; DNA-binding transcriptional dual regulator\tK10914 crp; CRP\/FNR family transcriptional regulator, cyclic AMP receptor protein"
				},
				{
					"name":"ECUMN_1629 fnr; DNA-binding transcriptional dual regulator, global regulator of anaerobic growth\tK01420 fnr; CRP\/FNR family transcriptional regulator, anaerobic regulatory protein"
				},
				{
					"name":"ECUMN_2499 yeiL; DNA-binding transcriptional activator of stationary phase nitrogen survival\tK16326 yeiL; CRP\/FNR family transcriptional regulator, putaive post-exponential-phase nitrogen-starvation regulator"
				}
				]
			},
			{
				"name":"Rrf2 family",
				"children":[
				{
					"name":"ECUMN_2851 iscR; DNA-binding transcriptional repressor\tK13643 iscR; Rrf2 family transcriptional regulator, iron-sulfur cluster assembly transcription factor"
				},
				{
					"name":"ECUMN_4711 nsrR; DNA-binding transcriptional regulator\tK13771 nsrR; Rrf2 family transcriptional regulator, nitric oxide-sensitive transcriptional repressor"
				}
				]
			},
			{
				"name":"ArsR family",
				"children":[
				{
					"name":"ECUMN_3989 arsR; DNA-binding transcriptional repressor\tK03892 arsR; ArsR family transcriptional regulator, arsenate\/arsenite\/antimonite-responsive transcriptional repressor"
				}
				]
			},
			{
				"name":"XRE family",
				"children":[
				{
					"name":"ECUMN_1681 ydcN; putative DNA-binding transcriptional regulator\tK23779 sutR; XRE family transcriptional regulator, regulator of sulfur utilization"
				}
				]
			},
			{
				"name":"PadR family"
			},
			{
				"name":"Other families",
				"children":[
				{
					"name":"ECUMN_1001 mntR; DNA-binding transcriptional regulator of mntH\tK11924 mntR; DtxR family transcriptional regulator, manganese transport regulator"
				},
				{
					"name":"ECUMN_2748 yfeT; putative DNA-binding transcriptional regulator\tK15835 murR; RpiR family transcriptional regulator, murPQ operon repressor"
				},
				{
					"name":"ECUMN_2151 yebK; putative DNA-binding transcriptional regulator\tK19337 hexR; RpiR family transcriptional regulator, carbohydrate utilization regulator"
				},
				{
					"name":"ECUMN_4499 birA; bifunctional biotin-[acetylCoA carboxylase] holoenzyme synthetase and DNA-binding transcriptional repressor, bio-5'-AMP-binding\tK03524 birA; BirA family transcriptional regulator, biotin operon repressor \/ biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]"
				},
				{
					"name":"ECUMN_3735 fis; global DNA-binding transcriptional dual regulator\tK03557 fis; Fis family transcriptional regulator, factor for inversion stimulation protein"
				},
				{
					"name":"ECUMN_5024 trpR; DNA-binding transcriptional repressor, tryptophan-binding\tK03720 trpR; TrpR family transcriptional regulator, trp operon repressor"
				},
				{
					"name":"ECUMN_0374 prpR; DNA-binding transcriptional activator\tK02688 prpR; transcriptional regulator, propionate catabolism operon regulatory protein"
				},
				{
					"name":"ECUMN_3668 sfsB; DNA-binding transcriptional activator of maltose metabolism\tK07724 ner; Ner family transcriptional regulator"
				},
				{
					"name":"ECUMN_0072 sgrR; DNA-binding transcriptional regulator\tK11925 sgrR; SgrR family transcriptional regulator"
				},
				{
					"name":"ECUMN_5014 nadR; bifunctional DNA-binding transcriptional repressor and NMN adenylyltransferase\tK06211 nadR; HTH-type transcriptional regulator, transcriptional repressor of NAD biosynthesis genes [EC:2.7.7.1 2.7.1.22]"
				},
				{
					"name":"ECUMN_3506 ygiT; putative DNA-binding transcriptional regulator\tK13655 mqsA; HTH-type transcriptional regulator \/ antitoxin MqsA"
				},
				{
					"name":"ECUMN_1605 puuR; DNA-binding transcriptional repressor\tK14056 puuR; HTH-type transcriptional regulator, repressor for puuD"
				},
				{
					"name":"ECUMN_1777 hipB; DNA-binding transcriptional regulator\tK15773 hipB; HTH-type transcriptional regulator \/ antitoxin HipB"
				},
				{
					"name":"ECUMN_1311 dicA; repressor protein of division inhibition from bacteriophage origin\tK22300 dicA; HTH-type transcriptional regulator, cell division transcriptional repressor"
				},
				{
					"name":"ECUMN_1855 dicA; putative repressor protein of division inhibition from phage origin\tK22300 dicA; HTH-type transcriptional regulator, cell division transcriptional repressor"
				},
				{
					"name":"ECUMN_3565 ygjM; putative DNA-binding transcriptional regulator\tK18831 higA; HTH-type transcriptional regulator \/ antitoxin HigA"
				},
				{
					"name":"ECUMN_2804 hyfR; DNA-binding transcriptional activator, formate sensing\tK12146 hyfR; hydrogenase-4 transcriptional activator"
				},
				{
					"name":"ECUMN_3030 norR; DNA-binding transcriptional activator\tK12266 norR; anaerobic nitric oxide reductase transcription regulator"
				},
				{
					"name":"ECUMN_3054 fhlA; DNA-binding transcriptional activator\tK15836 fhlA; formate hydrogenlyase transcriptional activator"
				},
				{
					"name":"ECUMN_0160 cdaR; DNA-binding transcriptional activator\tK02647 cdaR; carbohydrate diacid regulator"
				},
				{
					"name":"ECUMN_0846 modE; DNA-binding transcriptional dual regulator\tK02019 modE; molybdate transport system regulatory protein"
				},
				{
					"name":"ECUMN_3055 Putative molybdenum-pterin-binding-protein\tK02019 modE; molybdate transport system regulatory protein"
				},
				{
					"name":"ECUMN_4067 yiaG; putative transcriptional regulator\tK07726 K07726; putative transcriptional regulator"
				},
				{
					"name":"ECUMN_4189 conserved hypothetical protein, putative transcriptional regulator\tK07726 K07726; putative transcriptional regulator"
				},
				{
					"name":"ECUMN_0868 putative lambda repressor-like DNA-binding domains\tK07729 K07729; putative transcriptional regulator"
				}
				]
			}
			]
		},
		{
			"name":"Ribbon-helix-helix",
			"children":[
			{
				"name":"CopG family",
				"children":[
				{
					"name":"ECUMN_3962 nikR; DNA-binding transcriptional repressor, Ni-binding\tK07722 nikR; CopG family transcriptional regulator, nickel-responsive regulator"
				}
				]
			},
			{
				"name":"Other families",
				"children":[
				{
					"name":"ECUMN_4468 metJ; DNA-binding transcriptional repressor, S-adenosylmethionine-binding\tK03764 metJ; MetJ family transcriptional regulator, methionine regulon repressor"
				},
				{
					"name":"ECUMN_1197 putA; fused DNA-binding transcriptional regulator; proline dehydrogenase; pyrroline-5-carboxylate dehydrogenase\tK13821 putA; RHH-type transcriptional regulator, proline utilization regulon repressor \/ proline dehydrogenase \/ delta 1-pyrroline-5-carboxylate dehydrogenase [EC:1.5.5.2 1.2.1.88]"
				}
				]
			}
			]
		},
		{
			"name":"Other transcription factors",
			"children":[
			{
				"name":"BglG family"
			},
			{
				"name":"Others",
				"children":[
				{
					"name":"ECUMN_0400 frmR; regulator protein that represses frmRAB operon\tK23239 frmR; FrmR\/RcnR family transcriptional regulator, repressor of frmRAB operon"
				},
				{
					"name":"ECUMN_2437 yohL; conserved hypothetical protein\tK23240 rcnR; FrmR\/RcnR family transcriptional regulator, repressor of rcnA expression"
				},
				{
					"name":"ECUMN_0474 bolA; regulator of penicillin binding proteins and beta lactamase transcription (morphogene)\tK05527 bolA; BolA family transcriptional regulator, general stress-responsive regulator"
				},
				{
					"name":"ECUMN_p10123 ycjA; conserved hypothetical protein, putative ParB-like nuclease\tK03497 parB; ParB family transcriptional regulator, chromosome partitioning protein"
				},
				{
					"name":"ECUMN_4366 rfaH; DNA-binding transcriptional antiterminator\tK05785 rfaH; transcriptional antiterminator RfaH"
				},
				{
					"name":"ECUMN_3711 argR; DNA-binding transcriptional dual regulator, L-arginine-binding\tK03402 argR; transcriptional regulator of arginine metabolism"
				},
				{
					"name":"ECUMN_0761 nagC; DNA-binding transcriptional dual regulator, repressor of N-acetylglucosamine\tK02565 nagC; N-acetylglucosamine repressor"
				},
				{
					"name":"ECUMN_1879 dgsA; DNA-binding transcriptional repressor\tK15545 mlc; transcriptional regulator of PTS gene"
				},
				{
					"name":"ECUMN_4112 mtlR; DNA-binding repressor\tK02562 mtlR; mannitol operon repressor"
				},
				{
					"name":"ECUMN_1618 tyrR; DNA-binding transcriptional dual regulator, tyrosine-binding\tK03721 tyrR; transcriptional regulator of aroF, aroG, tyrA and aromatic amino acid transport"
				},
				{
					"name":"ECUMN_4667 cadC; DNA-binding transcriptional activator\tK03765 cadC; transcriptional activator of cad operon"
				},
				{
					"name":"ECUMN_3182 ygeH; putative transcriptional regulator\tK22486 hilA; transcriptional regulator HilA, main transcriptional regulator of SPI1"
				},
				{
					"name":"ECUMN_4185 putative Transcriptional regulator\tK22486 hilA; transcriptional regulator HilA, main transcriptional regulator of SPI1"
				},
				{
					"name":"ECUMN_2792 gcvR; DNA-binding transcriptional repressor, regulatory protein accessory to GcvA\tK03567 gcvR; glycine cleavage system transcriptional repressor"
				},
				{
					"name":"ECUMN_1609 pspF; DNA-binding transcriptional activator\tK03974 pspF; psp operon transcriptional activator"
				},
				{
					"name":"ECUMN_1613 pspC; DNA-binding transcriptional activator\tK03973 pspC; phage shock protein C"
				},
				{
					"name":"ECUMN_1780 lsrR; DNA-binding transcriptional regulator\tK11531 lsrR; lsr operon transcriptional repressor"
				},
				{
					"name":"ECUMN_1497 dhaR; DNA-binding transcriptional regulator, dihydroxyacetone metabolism\tK05880 dhaR; transcriptional activator for dhaKLM operon"
				},
				{
					"name":"ECUMN_0703 rnk; regulator of nucleoside diphosphate kinase\tK06140 rnk; regulator of nucleoside diphosphate kinase"
				},
				{
					"name":"ECUMN_4876 conserved hypothetical protein; putative InterPro motifs Prophage CP4-57 regulatory protein (AlpA)\tK07733 alpA; prophage regulatory protein"
				},
				{
					"name":"ECUMN_3300 yqgE; conserved hypothetical protein\tK07735 algH; putative transcriptional regulator"
				},
				{
					"name":"ECUMN_0036 caiF; transcriptional activator\tK08277 caiF; transcriptional activator CaiF"
				},
				{
					"name":"ECUMN_0142 dksA; DNA-binding transcriptional regulator of rRNA transcription, DnaK suppressor protein\tK06204 dksA; RNA polymerase-binding transcription factor"
				},
				{
					"name":"ECUMN_0451 nrdR; transcriptional repressor of nrd genes\tK07738 nrdR; transcriptional repressor NrdR"
				},
				{
					"name":"ECUMN_0306 crl; DNA-binding transcriptional regulator\tK11926 crl; sigma factor-binding protein Crl"
				},
				{
					"name":"ECUMN_3880 rtcR; sigma 54-dependent transcriptional regulator of rtcBA expression\tK14414 rtcR; transcriptional regulatory protein RtcR"
				},
				{
					"name":"ECUMN_1312 dicC; DNA-binding transcriptional regulator for DicB; Qin prophage\tK22302 dicC; transcriptional repressor of cell division inhibition gene dicB"
				},
				{
					"name":"ECUMN_1854 Repressor protein of division inhibition gene dicB\tK22302 dicC; transcriptional repressor of cell division inhibition gene dicB"
				},
				{
					"name":"ECUMN_0081 mraZ; conserved hypothetical protein\tK03925 mraZ; transcriptional regulator MraZ"
				},
				{
					"name":"ECUMN_3508 ygiV; putative transcriptional regulator\tK07471 ygiV; probable transcriptional regulator"
				}
				]
			}
			]
		}
		]
	}
	]
}