{
	"name":"fas03019",
	"children":[
	{
		"name":"Eukaryotic type",
		"children":[
		{
			"name":"mRNA processing factors",
			"children":[
			{
				"name":"5' end processing",
				"children":[
				{
					"name":"Capping factors",
					"children":[
					{
						"name":"105269236 mRNA-capping enzyme\tK13917 RNGTT; mRNA-capping enzyme [EC:2.7.7.50 3.6.1.74]"
					},
					{
						"name":"105273679 cyclin-dependent kinase 7\tK02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]"
					},
					{
						"name":"105271549 cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1\tK14589 CMTR1; cap1 methyltransferase [EC:2.1.1.57]"
					},
					{
						"name":"105264276 cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2\tK14590 CMTR2; cap2 methyltransferase [EC:2.1.1.296]"
					},
					{
						"name":"105267332 RNMT-activating mini protein\tK18708 FAM103A1; RNMT-activating mini protein"
					}
					]
				},
				{
					"name":"Cap binding complex",
					"children":[
					{
						"name":"105262984 nuclear cap-binding protein subunit 1\tK12882 NCBP1; nuclear cap-binding protein subunit 1"
					},
					{
						"name":"105264458 nuclear cap-binding protein subunit 2\tK12883 NCBP2; nuclear cap-binding protein subunit 2"
					}
					]
				}
				]
			},
			{
				"name":"3' end processing",
				"children":[
				{
					"name":"Pre-mRNA cleavage factor Im (CFIm)",
					"children":[
					{
						"name":"105274020 cleavage and polyadenylation specificity factor subunit 5\tK14397 NUDT21; cleavage and polyadenylation specificity factor subunit 5"
					},
					{
						"name":"105264523 cleavage and polyadenylation specificity factor subunit CG7185 isoform X1\tK14398 CPSF6_7; cleavage and polyadenylation specificity factor subunit 6\/7"
					}
					]
				},
				{
					"name":"Pre-mRNA cleavage factor IIm (CFIIm)",
					"children":[
					{
						"name":"105268627 protein CLP1 homolog\tK14399 CLP1; polyribonucleotide 5'-hydroxyl-kinase [EC:2.7.1.78]"
					},
					{
						"name":"105269762 uncharacterized protein LOC105269762 isoform X1\tK14400 PCF11; pre-mRNA cleavage complex 2 protein Pcf11"
					}
					]
				},
				{
					"name":"Cleavage and polyadenylation specificity factor (CPSF) complex",
					"children":[
					{
						"name":"105266354 cleavage and polyadenylation specificity factor subunit 1\tK14401 CPSF1; cleavage and polyadenylation specificity factor subunit 1"
					},
					{
						"name":"105268047 probable cleavage and polyadenylation specificity factor subunit 2\tK14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2"
					},
					{
						"name":"105268046 cleavage and polyadenylation specificity factor 73 isoform X1\tK14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]"
					},
					{
						"name":"105268045 cleavage and polyadenylation specificity factor subunit 4\tK14404 CPSF4; cleavage and polyadenylation specificity factor subunit 4"
					},
					{
						"name":"105265639 uncharacterized protein LOC105265639\tK15542 PFS2; polyadenylation factor subunit 2"
					},
					{
						"name":"105266952 WD repeat-containing protein 82\tK14962 WDR82; COMPASS component SWD2"
					},
					{
						"name":"105263279 serine\/threonine-protein phosphatase alpha-2 isoform\tK06269 PPP1C; serine\/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"105271457 serine\/threonine-protein phosphatase PP1-beta catalytic subunit isoform X1\tK06269 PPP1C; serine\/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"105265838 RNA polymerase II subunit A C-terminal domain phosphatase SSU72\tK15544 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 [EC:3.1.3.16]"
					}
					]
				},
				{
					"name":"Cleavage stimulation factor (CSTF) complex",
					"children":[
					{
						"name":"105263268 cleavage stimulation factor subunit 1\tK14406 CSTF1; cleavage stimulation factor subunit 1"
					},
					{
						"name":"105266553 cleavage stimulation factor subunit 2 tau variant-like isoform X1\tK14407 CSTF2; cleavage stimulation factor subunit 2"
					},
					{
						"name":"105266565 cleavage stimulation factor subunit 2-like isoform X1\tK14407 CSTF2; cleavage stimulation factor subunit 2"
					},
					{
						"name":"105270284 protein suppressor of forked\tK14408 CSTF3; cleavage stimulation factor subunit 3"
					},
					{
						"name":"105272458 symplekin\tK06100 SYMPK; symplekin"
					}
					]
				},
				{
					"name":"U7-dependent histone pre-mRNA processing factors",
					"children":[
					{
						"name":"105266174 small nuclear ribonucleoprotein-associated protein B\tK11086 SNRPB; small nuclear ribonucleoprotein B and B'"
					},
					{
						"name":"105267159 small nuclear ribonucleoprotein Sm D3\tK11088 SNRPD3; small nuclear ribonucleoprotein D3"
					},
					{
						"name":"105271370 probable small nuclear ribonucleoprotein E\tK11097 SNRPE; small nuclear ribonucleoprotein E"
					},
					{
						"name":"105269566 small nuclear ribonucleoprotein F\tK11098 SNRPF; small nuclear ribonucleoprotein F"
					},
					{
						"name":"105262756 probable small nuclear ribonucleoprotein G\tK11099 SNRPG; small nuclear ribonucleoprotein G"
					},
					{
						"name":"105273576 U7 snRNA-associated Sm-like protein LSm10\tK25591 LSM10; U7 snRNA-associated Sm-like protein LSm10"
					},
					{
						"name":"105271641 U7 snRNA-associated Sm-like protein LSm11\tK25592 LSM11; U7 snRNA-associated Sm-like protein LSm11"
					},
					{
						"name":"105268047 probable cleavage and polyadenylation specificity factor subunit 2\tK14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2"
					},
					{
						"name":"105268046 cleavage and polyadenylation specificity factor 73 isoform X1\tK14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]"
					},
					{
						"name":"105266553 cleavage stimulation factor subunit 2 tau variant-like isoform X1\tK14407 CSTF2; cleavage stimulation factor subunit 2"
					},
					{
						"name":"105266565 cleavage stimulation factor subunit 2-like isoform X1\tK14407 CSTF2; cleavage stimulation factor subunit 2"
					},
					{
						"name":"105272458 symplekin\tK06100 SYMPK; symplekin"
					},
					{
						"name":"105271525 histone RNA hairpin-binding protein\tK18710 SLBP; histone RNA hairpin-binding protein"
					}
					]
				},
				{
					"name":"DRB sensitivity inducing factor (DSIF) complex",
					"children":[
					{
						"name":"105263047 transcription elongation factor SPT4\tK15171 SUPT4H1; transcription elongation factor SPT4"
					},
					{
						"name":"105268436 transcription elongation factor SPT5-like\tK15172 SUPT5H; transcription elongation factor SPT5"
					},
					{
						"name":"105268509 transcription elongation factor SPT5-like\tK15172 SUPT5H; transcription elongation factor SPT5"
					}
					]
				},
				{
					"name":"N6-methyltransferase complex",
					"children":[
					{
						"name":"105265102 N6-adenosine-methyltransferase subunit METTL3 isoform X1\tK05925 METTL3; mRNA m6A methyltransferase catalytic subunit [EC:2.1.1.348]"
					},
					{
						"name":"105267388 methyltransferase-like protein 14 homolog\tK23960 METTL14; mRNA m6A methyltransferase non-catalytic subunit"
					},
					{
						"name":"105272184 methyltransferase-like protein 4\tK24174 METTL4; N(6)-adenine-specific DNA methyltransferase [EC:2.1.1.72]"
					},
					{
						"name":"105269043 methyltransferase-like protein 16 homolog\tK11393 METTL16; U6 snRNA m6A methyltransferase [EC:2.1.1.346]"
					},
					{
						"name":"105265720 pre-mRNA-splicing regulator WTAP\tK22824 WTAP; pre-mRNA-splicing regulator WTAP"
					},
					{
						"name":"105270999 protein virilizer isoform X1\tK22910 VIRMA; protein virilizer"
					},
					{
						"name":"105265331 putative RNA-binding protein 15\tK13190 RBM15; RNA-binding protein 15"
					},
					{
						"name":"105268307 zinc finger CCCH domain-containing protein 13\tK22909 ZC3H13; zinc finger CCCH domain-containing protein 13"
					},
					{
						"name":"105272541 E3 ubiquitin-protein ligase Hakai isoform X1\tK15685 CBLL1; E3 ubiquitin-protein ligase Hakai [EC:2.3.2.27]"
					}
					]
				},
				{
					"name":"Poly(A) addition factors",
					"children":[
					{
						"name":"105273612 poly(A) polymerase type 3\tK14376 PAP; poly(A) polymerase [EC:2.7.7.19]"
					},
					{
						"name":"105270434 poly(A) RNA polymerase gld-2 homolog A-like\tK14079 PAPD4; poly(A) RNA polymerase GLD2 [EC:2.7.7.19]"
					},
					{
						"name":"105264115 speckle targeted PIP5K1A-regulated poly(A) polymerase-like\tK18709 TUT1; speckle targeted PIP5K1A-regulated poly(A) polymerase [EC:2.7.7.19 2.7.7.52]"
					}
					]
				},
				{
					"name":"Negative regulators of mRNA 3' end processing",
					"children":[
					{
						"name":"105266682 RNA-binding motif protein, X-linked 2-like\tK23600 TARDBP; TAR DNA-binding protein 43"
					},
					{
						"name":"105272985 TAR DNA-binding protein 43-like\tK23600 TARDBP; TAR DNA-binding protein 43"
					}
					]
				}
				]
			},
			{
				"name":"Other processing factors",
				"children":[
				{
					"name":"105270762 DNA\/RNA-binding protein KIN17\tK13102 KIN; DNA\/RNA-binding protein KIN17"
				},
				{
					"name":"105271053 methyltransferase-like protein 22\tK23040 METTL22; methyltransferase-like protein 22 [EC:2.1.1.-]"
				},
				{
					"name":"105265161 protein FAM46C isoform X1\tK23034 TENT5C; terminal nucleotidyltransferase 5C [EC:2.7.7.19]"
				},
				{
					"name":"105267524 zinc finger CCCH domain-containing protein 14-like\tK23038 ZC3H14; zinc finger CCCH domain-containing protein 14"
				},
				{
					"name":"105266393 serrate RNA effector molecule homolog isoform X1\tK27103 SRRT; serrate RNA effector molecule"
				}
				]
			}
			]
		},
		{
			"name":"mRNA surveillance and transport factors",
			"children":[
			{
				"name":"Transport factors",
				"children":[
				{
					"name":"EJC complex",
					"children":[
					{
						"name":"105268925 RNA-binding protein 8A\tK12876 RBM8A; RNA-binding protein 8A"
					},
					{
						"name":"105269027 protein mago nashi homolog\tK12877 MAGOH; protein mago nashi"
					},
					{
						"name":"105269971 THO complex subunit 4-like isoform X1\tK12881 THOC4; THO complex subunit 4"
					},
					{
						"name":"105266953 ATP-dependent RNA helicase WM6\tK12812 DDX39B; ATP-dependent RNA helicase UAP56\/SUB2 [EC:5.6.2.7]"
					},
					{
						"name":"105266767 eukaryotic initiation factor 4A-III\tK13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7]"
					},
					{
						"name":"105267909 coiled-coil domain-containing protein 174\tK25178 CCDC174; coiled-coil domain-containing protein 174"
					},
					{
						"name":"105270462 protein CASC3 isoform X1\tK14323 CASC3; protein CASC3"
					},
					{
						"name":"105266424 histone deacetylase complex subunit SAP18\tK14324 SAP18; histone deacetylase complex subunit SAP18"
					},
					{
						"name":"105267445 apoptotic chromatin condensation inducer in the nucleus\tK12875 ACIN1; apoptotic chromatin condensation inducer in the nucleus"
					},
					{
						"name":"105270446 RNA-binding protein with serine-rich domain 1-B\tK14325 RNPS1; RNA-binding protein with serine-rich domain 1"
					},
					{
						"name":"105272188 serine\/arginine repetitive matrix protein 1-like isoform X1\tK13171 SRRM1; serine\/arginine repetitive matrix protein 1"
					}
					]
				},
				{
					"name":"TREX complex",
					"children":[
					{
						"name":"105273968 THO complex subunit 1\tK12878 THOC1; THO complex subunit 1"
					},
					{
						"name":"105262714 THO complex subunit 2\tK12879 THOC2; THO complex subunit 2"
					},
					{
						"name":"105263448 THO complex subunit 3\tK12880 THOC3; THO complex subunit 3"
					},
					{
						"name":"105269971 THO complex subunit 4-like isoform X1\tK12881 THOC4; THO complex subunit 4"
					},
					{
						"name":"105269862 THO complex subunit 5 homolog\tK13174 THOC5; THO complex subunit 5"
					},
					{
						"name":"105264871 THO complex subunit 6 homolog\tK13175 THOC6; THO complex subunit 6"
					},
					{
						"name":"105271300 THO complex subunit 7 homolog\tK13176 THOC7; THO complex subunit 7"
					}
					]
				},
				{
					"name":"TREX-2 complex",
					"children":[
					{
						"name":"105271968 PCI domain-containing protein 2\tK23801 PCID2; nuclear mRNA export protein PCID2\/THP1"
					},
					{
						"name":"105266845 26S proteasome complex subunit DSS1\tK10881 SHFM1; 26 proteasome complex subunit DSS1"
					},
					{
						"name":"105264407 transcription and mRNA export factor ENY2\tK11368 ENY2; enhancer of yellow 2 transcription factor"
					}
					]
				},
				{
					"name":"Nuclear pore complex",
					"children":[
					{
						"name":"105265414 nucleoprotein TPR\tK09291 TPR; nucleoprotein TPR"
					},
					{
						"name":"105271584 mRNA export factor\tK14298 RAE1; mRNA export factor"
					},
					{
						"name":"105268323 protein SEC13 homolog\tK14004 SEC13; protein transport protein SEC13"
					},
					{
						"name":"105267063 nucleoporin Nup37\tK14302 NUP37; nuclear pore complex protein Nup37"
					},
					{
						"name":"105272023 nuclear pore complex protein Nup85\tK14304 NUP85; nuclear pore complex protein Nup85"
					},
					{
						"name":"105265884 nucleoporin Nup43\tK14305 NUP43; nuclear pore complex protein Nup43"
					},
					{
						"name":"105274149 nuclear pore complex protein Nup50\tK14295 NUP50; nuclear pore complex protein Nup50"
					},
					{
						"name":"105264542 nuclear pore complex protein Nup54\tK14308 NUP54; nuclear pore complex protein Nup54"
					},
					{
						"name":"105267249 nuclear pore glycoprotein p62\tK14306 NUP62; nuclear pore complex protein Nup62"
					},
					{
						"name":"105264421 nuclear pore complex protein Nup88\tK14318 NUP88; nuclear pore complex protein Nup88"
					},
					{
						"name":"105271200 nuclear pore complex protein Nup93-like\tK14309 NUP93; nuclear pore complex protein Nup93"
					},
					{
						"name":"105269446 nuclear pore complex protein Nup98-Nup96\tK14297 NUP98; nuclear pore complex protein Nup98-Nup96"
					},
					{
						"name":"105263695 nuclear pore complex protein Nup107\tK14301 NUP107; nuclear pore complex protein Nup107"
					},
					{
						"name":"105263478 nuclear pore complex protein Nup133\tK14300 NUP133; nuclear pore complex protein Nup133"
					},
					{
						"name":"105269660 nucleoporin NUP188 homolog\tK14311 NUP188; nuclear pore complex protein Nup188"
					},
					{
						"name":"105273263 nuclear pore complex protein Nup153\tK14296 NUP153; nuclear pore complex protein Nup153"
					},
					{
						"name":"105273122 nuclear pore complex protein Nup155\tK14312 NUP155; nuclear pore complex protein Nup155"
					},
					{
						"name":"105271711 nuclear pore complex protein Nup160 homolog\tK14303 NUP160; nuclear pore complex protein Nup160"
					},
					{
						"name":"105265775 nucleoporin NUP53\tK14313 NUP35; nuclear pore complex protein Nup53"
					},
					{
						"name":"105269592 nuclear pore complex protein Nup205\tK14310 NUP205; nuclear pore complex protein Nup205"
					},
					{
						"name":"105264699 nuclear pore membrane glycoprotein 210\tK14314 NUP210; nuclear pore complex protein Nup210"
					},
					{
						"name":"105266499 nuclear pore complex protein Nup214\tK14317 NUP214; nuclear pore complex protein Nup214"
					},
					{
						"name":"105263233 probable nucleoporin Nup58 isoform X1\tK14307 NUPL1; nucleoporin p58\/p45"
					},
					{
						"name":"105272082 nuclear pore complex protein NUP98A-like isoform X1\tK14321 NUPL2; nucleoporin-like protein 2"
					},
					{
						"name":"105267683 nucleoporin NDC1\tK14315 NDC1; nucleoporin NDC1"
					},
					{
						"name":"105263831 nucleoporin seh1-A\tK14299 SEH1; nucleoporin SEH1"
					},
					{
						"name":"105269604 E3 SUMO-protein ligase RanBP2-like\tK12172 RANBP2; E3 SUMO-protein ligase RanBP2 [EC:2.3.2.-]"
					},
					{
						"name":"105271318 aladin\tK14320 AAAS; aladin"
					},
					{
						"name":"105265730 nucleoporin GLE1\tK18723 GLE1; nucleoporin GLE1"
					},
					{
						"name":"105263202 nuclear RNA export factor 1-like\tK14284 NXF; nuclear RNA export factor"
					},
					{
						"name":"105265120 nuclear RNA export factor 1-like\tK14284 NXF; nuclear RNA export factor"
					},
					{
						"name":"105264264 NTF2-related export protein\tK14285 NXT1_2; NTF2-related export protein 1\/2"
					}
					]
				},
				{
					"name":"Ran-mediated transport factors",
					"children":[
					{
						"name":"105267697 GTP-binding nuclear protein Ran\tK07936 RAN; GTP-binding nuclear protein Ran"
					},
					{
						"name":"105272395 acidic leucine-rich nuclear phosphoprotein 32 family member A\tK18646 ANP32A_C_D; acidic leucine-rich nuclear phosphoprotein 32 family member A\/C\/D"
					},
					{
						"name":"105266338 ELAV-like protein 3 isoform X1\tK13208 ELAVL2_3_4; ELAV like protein 2\/3\/4"
					},
					{
						"name":"105272083 FAS-associated factor 2\tK18726 FAF2; FAS-associated factor 2"
					},
					{
						"name":"105264610 transitional endoplasmic reticulum ATPase TER94\tK13525 VCP; transitional endoplasmic reticulum ATPase"
					},
					{
						"name":"105267684 protein-lysine methyltransferase METTL21D-like isoform X1\tK21806 VCPKMT; protein N-lysine methyltransferase METTL21D [EC:2.1.1.-]"
					},
					{
						"name":"105271606 exportin-1\tK14290 XPO1; exportin-1"
					},
					{
						"name":"105262729 exportin-7 isoform X1\tK18460 XPO7; exportin-7"
					},
					{
						"name":"105274011 ran GTPase-activating protein 1\tK14319 RANGAP1; Ran GTPase-activating protein 1"
					},
					{
						"name":"105270009 probable nuclear transport factor 2 isoform X1\tK28773 NUTF2; nuclear transport factor 2"
					}
					]
				},
				{
					"name":"eIF4F and regulatory proteins",
					"children":[
					{
						"name":"105266847 eukaryotic translation initiation factor 4E type 2\tK03259 EIF4E; translation initiation factor 4E"
					},
					{
						"name":"105266913 eukaryotic translation initiation factor 4E-1A-like isoform X1\tK03259 EIF4E; translation initiation factor 4E"
					},
					{
						"name":"105268345 eukaryotic initiation factor 4A\tK03257 EIF4A; translation initiation factor 4A"
					},
					{
						"name":"105263601 eukaryotic translation initiation factor 4 gamma 2 isoform X1\tK03260 EIF4G; translation initiation factor 4G"
					},
					{
						"name":"105268546 eukaryotic translation initiation factor 4 gamma 3-like isoform X1\tK03260 EIF4G; translation initiation factor 4G"
					},
					{
						"name":"105270646 eukaryotic translation initiation factor 4B-like\tK03258 EIF4B; translation initiation factor 4B"
					},
					{
						"name":"105268745 eukaryotic translation initiation factor 4H-like\tK24086 EIF4H; translation initiation factor 4H"
					},
					{
						"name":"105273353 eukaryotic translation initiation factor 4E-binding protein 2\tK18644 EIF4EBP2; eukaryotic translation initiation factor 4E binding protein 2"
					},
					{
						"name":"105267904 eukaryotic translation initiation factor 4E transporter isoform X1\tK18728 EIF4ENIF1; eukaryotic translation initiation factor 4E transporter"
					},
					{
						"name":"105266366 protein angel isoform X1\tK18729 ANGEL; protein angel"
					},
					{
						"name":"105263346 fragile X mental retardation syndrome-related protein 1 isoform X1\tK15516 FMR; fragile X mental retardation protein"
					},
					{
						"name":"105270227 cytoplasmic FMR1-interacting protein\tK05749 CYFIP; cytoplasmic FMR1 interacting protein"
					},
					{
						"name":"105263990 cytoplasmic polyadenylation element-binding protein 3\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein"
					},
					{
						"name":"105271683 cytoplasmic polyadenylation element-binding protein 1 isoform X1\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein"
					},
					{
						"name":"105267686 ATP-dependent RNA helicase DDX3X\tK11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]"
					},
					{
						"name":"105268523 PERQ amino acid-rich with GYF domain-containing protein 2\tK18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein"
					},
					{
						"name":"105263546 polyadenylate-binding protein\tK13126 PABPC; polyadenylate-binding protein"
					},
					{
						"name":"105267187 polyadenylate-binding protein-interacting protein 1 isoform X1\tK14322 PAIP1; polyadenylate-binding protein-interacting protein 1"
					},
					{
						"name":"105263732 polyadenylate-binding protein-interacting protein 2 isoform X1\tK27470 PAIP2; polyadenylate-binding protein-interacting protein 2"
					},
					{
						"name":"105268330 helicase SKI2W\tK12599 SKI2; antiviral helicase SKI2 [EC:5.6.2.6]"
					},
					{
						"name":"105265010 deformed epidermal autoregulatory factor 1 isoform X1\tK23041 DEAF1; deformed epidermal autoregulatory factor 1"
					},
					{
						"name":"105265957 malignant T-cell-amplified sequence 1\tK07575 MCTS; malignant T-cell-amplified sequence"
					},
					{
						"name":"105269099 density-regulated protein\tK24272 DENR; density-regulated protein"
					}
					]
				},
				{
					"name":"APOBEC1-ACF complex"
				},
				{
					"name":"Other transport factors",
					"children":[
					{
						"name":"105269256 partner of Y14 and mago\tK14294 WIBG; partner of Y14 and mago"
					},
					{
						"name":"105267212 heterogeneous nuclear ribonucleoprotein A1, A2\/B1 homolog isoform X1\tK12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1\/A3"
					},
					{
						"name":"105262879 RNA-binding protein Musashi homolog 2-like isoform X1\tK14411 MSI; RNA-binding protein Musashi"
					},
					{
						"name":"105263006 RNA-binding protein Musashi homolog Rbp6 isoform X1\tK14411 MSI; RNA-binding protein Musashi"
					},
					{
						"name":"105270425 heterogeneous nuclear ribonucleoprotein 27C-like isoform X1\tK14411 MSI; RNA-binding protein Musashi"
					},
					{
						"name":"105274027 HBS1-like protein isoform X1\tK14416 HBS1; elongation factor 1 alpha-like protein"
					},
					{
						"name":"105269935 protein pelota\tK06965 PELO; protein pelota"
					},
					{
						"name":"105264711 polyadenylate-binding protein 2-B isoform X1\tK14396 PABPN1; polyadenylate-binding protein 2"
					},
					{
						"name":"105265722 DEAD-box helicase Dbp80\tK18655 DDX19; ATP-dependent RNA helicase DDX19\/DBP5 [EC:5.6.2.7]"
					},
					{
						"name":"105270602 pre-mRNA-splicing factor SYF1\tK12867 SYF1; pre-mRNA-splicing factor SYF1"
					},
					{
						"name":"105269907 SAP domain-containing ribonucleoprotein isoform X1\tK18732 SARNP; SAP domain-containing ribonucleoprotein"
					},
					{
						"name":"105272128 la-related protein 6\tK18733 LARP6; la-related protein 6"
					},
					{
						"name":"105271316 transcriptional activator protein Pur-beta isoform X1\tK21772 PURA; transcriptional activator protein Pur-alpha"
					},
					{
						"name":"105271848 uncharacterized protein LOC105271848\tK22414 POLDIP3; polymerase delta-interacting protein 3"
					},
					{
						"name":"105270417 zinc finger CCCH domain-containing protein 11A-like isoform X1\tK22415 ZC3H11; zinc finger CCCH domain-containing protein 11"
					},
					{
						"name":"105266705 leukocyte receptor cluster member 8 homolog\tK23802 LENG8; SAC3 family protein LENG8\/THP3"
					}
					]
				}
				]
			},
			{
				"name":"Surveillance factors",
				"children":[
				{
					"name":"Surveillance complex",
					"children":[
					{
						"name":"105267265 eukaryotic peptide chain release factor subunit 1 isoform X1\tK03265 ETF1; peptide chain release factor subunit 1"
					},
					{
						"name":"105263734 eukaryotic peptide chain release factor GTP-binding subunit ERF3A isoform X1\tK03267 ERF3; peptide chain release factor subunit 3"
					},
					{
						"name":"105270435 regulator of nonsense transcripts 1 homolog\tK14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3]"
					},
					{
						"name":"105273934 regulator of nonsense transcripts 2\tK14327 UPF2; regulator of nonsense transcripts 2"
					},
					{
						"name":"105267078 LOW QUALITY PROTEIN: regulator of nonsense transcripts 3A\tK14328 UPF3; regulator of nonsense transcripts 3"
					}
					]
				},
				{
					"name":"Protein phosphatase 2A",
					"children":[
					{
						"name":"105267334 serine\/threonine-protein phosphatase 2A catalytic subunit alpha isoform\tK04382 PPP2C; serine\/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"105272100 serine\/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform isoform X1\tK03456 PPP2R1; serine\/threonine-protein phosphatase 2A regulatory subunit A"
					},
					{
						"name":"105264149 serine\/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform isoform X1\tK04354 PPP2R2; serine\/threonine-protein phosphatase 2A regulatory subunit B"
					},
					{
						"name":"105266795 uncharacterized protein LOC105266795\tK11583 PPP2R3; serine\/threonine-protein phosphatase 2A regulatory subunit B''"
					},
					{
						"name":"105274210 serine\/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma-like\tK11583 PPP2R3; serine\/threonine-protein phosphatase 2A regulatory subunit B''"
					},
					{
						"name":"105268562 serine\/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform-like isoform X1\tK11584 PPP2R5; serine\/threonine-protein phosphatase 2A regulatory subunit B'"
					},
					{
						"name":"105270636 serine\/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform\tK11584 PPP2R5; serine\/threonine-protein phosphatase 2A regulatory subunit B'"
					}
					]
				},
				{
					"name":"Other surveillance factors",
					"children":[
					{
						"name":"105266247 serine\/threonine-protein kinase SMG1 isoform X1\tK08873 SMG1; serine\/threonine-protein kinase SMG1 [EC:2.7.11.1]"
					},
					{
						"name":"105270532 protein SMG5\tK11125 SMG5; protein SMG5"
					},
					{
						"name":"105268393 telomerase-binding protein EST1A-like isoform X1\tK11124 SMG6; protein SMG6 [EC:3.1.-.-]"
					},
					{
						"name":"105273414 protein SMG7-like\tK14409 SMG7; protein SMG7"
					},
					{
						"name":"105268686 protein SMG8\tK18734 SMG8; protein SMG8"
					},
					{
						"name":"105265437 protein SMG9\tK18735 SMG9; protein SMG9"
					},
					{
						"name":"105268523 PERQ amino acid-rich with GYF domain-containing protein 2\tK18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein"
					},
					{
						"name":"105271398 probable ATP-dependent RNA helicase DHX34\tK20101 DHX34; ATP-dependent RNA helicase DHX34 [EC:5.6.2.6]"
					},
					{
						"name":"105268997 GTP-binding protein 1\tK24887 GTPBP1; GTP-binding protein 1"
					}
					]
				}
				]
			},
			{
				"name":"Factors involved in mRNA localization",
				"children":[
				{
					"name":"Cargo complex",
					"children":[
					{
						"name":"105269151 pumilio domain-containing protein KIAA0020\tK14844 PUF6; pumilio homology domain family member 6"
					},
					{
						"name":"105262752 unconventional myosin-Va isoform X1\tK10357 MYO5; myosin V"
					},
					{
						"name":"105268799 protein bicaudal D isoform X1\tK18739 BICD; protein bicaudal D"
					},
					{
						"name":"105269165 uncharacterized protein LOC105269165\tK18740 EXD1; exonuclease 3'-5' domain-containing protein 1"
					}
					]
				},
				{
					"name":"Factors that have mRNA localization signals",
					"children":[
					{
						"name":"105263314 actin, clone 403-like\tK05692 ACTB_G1; actin beta\/gamma 1"
					},
					{
						"name":"105265531 actin-5C\tK05692 ACTB_G1; actin beta\/gamma 1"
					},
					{
						"name":"105273969 N-myc 2 proto-oncogene protein\tK04377 MYC; Myc proto-oncogene protein"
					},
					{
						"name":"105269115 T-box-containing protein TBX6L-like\tK10180 TBX6; T-box protein 6"
					},
					{
						"name":"105264106 nanos homolog 2\tK18741 NANOS1; protein nanos 1"
					},
					{
						"name":"105267990 uncharacterized protein LOC105267990\tK18742 OSK; maternal effect protein oskar"
					},
					{
						"name":"105272054 enhancer of split mbeta protein-like\tK09090 HESN; hairy and enhancer of split, invertebrate"
					},
					{
						"name":"105272056 enhancer of split m7 protein-like\tK09090 HESN; hairy and enhancer of split, invertebrate"
					},
					{
						"name":"105272058 enhancer of split mbeta protein-like\tK09090 HESN; hairy and enhancer of split, invertebrate"
					},
					{
						"name":"105273783 protein hairy\tK09090 HESN; hairy and enhancer of split, invertebrate"
					},
					{
						"name":"105273791 transcription factor HES-1\tK09090 HESN; hairy and enhancer of split, invertebrate"
					}
					]
				},
				{
					"name":"Trans-acting binding proteins",
					"children":[
					{
						"name":"105274274 far upstream element-binding protein 3\tK13210 FUBP; far upstream element-binding protein"
					},
					{
						"name":"105266014 elongation factor 1-alpha\tK03231 EEF1A; elongation factor 1-alpha"
					},
					{
						"name":"105267360 elongation factor 1-alpha\tK03231 EEF1A; elongation factor 1-alpha"
					},
					{
						"name":"105272497 elongation factor 1-gamma\tK03233 EEF1G; elongation factor 1-gamma"
					},
					{
						"name":"105273834 HCLS1-associated protein X-1\tK16220 HAX1; HCLS1-associated protein X-1"
					},
					{
						"name":"105267409 arf-GAP domain and FG repeat-containing protein 1 isoform X1\tK15044 AGFG1; Arf-GAP domain and FG repeats-containing protein 1"
					},
					{
						"name":"105263481 double-stranded RNA-binding protein Staufen homolog 2 isoform X1\tK17597 STAU; double-stranded RNA-binding protein Staufen"
					},
					{
						"name":"105270920 polypyrimidine tract-binding protein 1 isoform X1\tK13218 PTBP1; polypyrimidine tract-binding protein 1"
					},
					{
						"name":"105266423 RNA-binding protein squid isoform X1\tK03102 SQD; squid"
					},
					{
						"name":"105273899 RNA-binding protein squid-like\tK03102 SQD; squid"
					},
					{
						"name":"105263990 cytoplasmic polyadenylation element-binding protein 3\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein"
					},
					{
						"name":"105271683 cytoplasmic polyadenylation element-binding protein 1 isoform X1\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein"
					}
					]
				},
				{
					"name":"Other mRNA localization factors",
					"children":[
					{
						"name":"105263346 fragile X mental retardation syndrome-related protein 1 isoform X1\tK15516 FMR; fragile X mental retardation protein"
					},
					{
						"name":"105270227 cytoplasmic FMR1-interacting protein\tK05749 CYFIP; cytoplasmic FMR1 interacting protein"
					},
					{
						"name":"105265456 poly(rC)-binding protein 3 isoform X1\tK21444 PCBP3_4; poly(rC)-binding protein 3\/4"
					},
					{
						"name":"105269906 caprin homolog\tK18743 CAPRIN1; caprin-1"
					},
					{
						"name":"105263895 CUGBP Elav-like family member 1 isoform X1\tK02177 BRU; bruno"
					},
					{
						"name":"105263812 maternal protein exuperantia\tK18745 EXU; maternal protein exuperantia"
					},
					{
						"name":"105268871 Y-box factor homolog isoform X1\tK09276 YBX1; Y-box-binding protein 1"
					},
					{
						"name":"105268681 sex-lethal homolog\tK18747 SXL; protein sex-lethal"
					}
					]
				}
				]
			},
			{
				"name":"mRNA cycle factors",
				"children":[
				{
					"name":"Common to processing body (P body) and stress granule",
					"children":[
					{
						"name":"105269019 5'-3' exoribonuclease 1\tK12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]"
					},
					{
						"name":"105269274 protein argonaute-2 isoform X1\tK11593 ELF2C; eukaryotic translation initiation factor 2C"
					},
					{
						"name":"105271515 protein argonaute-2 isoform X1\tK11593 ELF2C; eukaryotic translation initiation factor 2C"
					},
					{
						"name":"105266847 eukaryotic translation initiation factor 4E type 2\tK03259 EIF4E; translation initiation factor 4E"
					},
					{
						"name":"105266913 eukaryotic translation initiation factor 4E-1A-like isoform X1\tK03259 EIF4E; translation initiation factor 4E"
					},
					{
						"name":"105270435 regulator of nonsense transcripts 1 homolog\tK14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3]"
					},
					{
						"name":"105267686 ATP-dependent RNA helicase DDX3X\tK11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]"
					},
					{
						"name":"105274280 putative ATP-dependent RNA helicase me31b\tK12614 DDX6; ATP-dependent RNA helicase DDX6\/DHH1 [EC:5.6.2.7]"
					},
					{
						"name":"105272375 RNA-binding protein MEX3B\tK15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]"
					},
					{
						"name":"105263407 protein LSM14 homolog B-A isoform X1\tK18749 LSM14; protein LSM14"
					},
					{
						"name":"105268871 Y-box factor homolog isoform X1\tK09276 YBX1; Y-box-binding protein 1"
					},
					{
						"name":"105263491 LIM domain-containing protein jub\tK16682 AJUBA; LIM domain-containing protein"
					},
					{
						"name":"105268647 putative helicase mov-10-B.1\tK18422 MOV10; helicase MOV-10 [EC:5.6.2.5]"
					},
					{
						"name":"105271944 proline-rich nuclear receptor coactivator 2\tK18751 PNRC2; proline-rich nuclear receptor coactivator 2"
					},
					{
						"name":"105268188 transportin-1\tK18752 TNPO1; transportin-1"
					},
					{
						"name":"105266247 serine\/threonine-protein kinase SMG1 isoform X1\tK08873 SMG1; serine\/threonine-protein kinase SMG1 [EC:2.7.11.1]"
					},
					{
						"name":"105270532 protein SMG5\tK11125 SMG5; protein SMG5"
					},
					{
						"name":"105268393 telomerase-binding protein EST1A-like isoform X1\tK11124 SMG6; protein SMG6 [EC:3.1.-.-]"
					},
					{
						"name":"105273414 protein SMG7-like\tK14409 SMG7; protein SMG7"
					},
					{
						"name":"105271558 protein TIS11\tK18753 ZFP36L; butyrate response factor"
					},
					{
						"name":"105270407 huntingtin\tK04533 HD; huntingtin"
					},
					{
						"name":"105267386 protein bicaudal C isoform X1\tK18756 BICC1; protein bicaudal C"
					},
					{
						"name":"105267212 heterogeneous nuclear ribonucleoprotein A1, A2\/B1 homolog isoform X1\tK12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1\/A3"
					},
					{
						"name":"105263721 cAMP-dependent protein kinase catalytic subunit\tK04345 PKA; protein kinase A [EC:2.7.11.11]"
					},
					{
						"name":"105265054 cAMP-dependent protein kinase catalytic subunit-like\tK04345 PKA; protein kinase A [EC:2.7.11.11]"
					},
					{
						"name":"105263996 la-related protein 1 isoform X1\tK18757 LARP1; la-related protein 1"
					},
					{
						"name":"105269134 ataxin-2\tK23625 ATXN2; ataxin-2"
					}
					]
				},
				{
					"name":"P-body specific factors",
					"children":[
					{
						"name":"105264168 m7GpppN-mRNA hydrolase isoform X1\tK12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62]"
					},
					{
						"name":"105273826 mRNA-decapping enzyme 1A\tK12611 DCP1B; mRNA-decapping enzyme 1B [EC:3.-.-.-]"
					},
					{
						"name":"105263987 U6 snRNA-associated Sm-like protein LSm1\tK12620 LSM1; U6 snRNA-associated Sm-like protein LSm1"
					},
					{
						"name":"105268660 U6 snRNA-associated Sm-like protein LSm2\tK12621 LSM2; U6 snRNA-associated Sm-like protein LSm2"
					},
					{
						"name":"105266108 U6 snRNA-associated Sm-like protein LSm3\tK12622 LSM3; U6 snRNA-associated Sm-like protein LSm3"
					},
					{
						"name":"105266954 U6 snRNA-associated Sm-like protein LSm4\tK12623 LSM4; U6 snRNA-associated Sm-like protein LSm4"
					},
					{
						"name":"105274117 U6 snRNA-associated Sm-like protein LSm5 isoform X1\tK12624 LSM5; U6 snRNA-associated Sm-like protein LSm5"
					},
					{
						"name":"105264644 U6 snRNA-associated Sm-like protein LSm6\tK12625 LSM6; U6 snRNA-associated Sm-like protein LSm6"
					},
					{
						"name":"105270460 U6 snRNA-associated Sm-like protein LSm7\tK12626 LSM7; U6 snRNA-associated Sm-like protein LSm7"
					},
					{
						"name":"105270915 U6 snRNA-associated Sm-like protein LSm8\tK12627 LSM8; U6 snRNA-associated Sm-like protein LSm8"
					},
					{
						"name":"105264197 kinesin light chain isoform X1\tK10407 KLC; kinesin light chain"
					},
					{
						"name":"105262752 unconventional myosin-Va isoform X1\tK10357 MYO5; myosin V"
					},
					{
						"name":"105263575 tubulin alpha chain-like isoform X1\tK07374 TUBA; tubulin alpha"
					},
					{
						"name":"105265458 tubulin alpha-1 chain-like\tK07374 TUBA; tubulin alpha"
					},
					{
						"name":"105266480 tubulin alpha-2 chain-like isoform X1\tK07374 TUBA; tubulin alpha"
					},
					{
						"name":"105271988 tubulin alpha-1 chain\tK07374 TUBA; tubulin alpha"
					},
					{
						"name":"105263990 cytoplasmic polyadenylation element-binding protein 3\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein"
					},
					{
						"name":"105271683 cytoplasmic polyadenylation element-binding protein 1 isoform X1\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein"
					},
					{
						"name":"105263784 protein Gawky isoform X1\tK18412 TNRC6; trinucleotide repeat-containing gene 6 protein"
					},
					{
						"name":"105270081 CCR4-NOT transcription complex subunit 1\tK12604 CNOT1; CCR4-NOT transcription complex subunit 1"
					},
					{
						"name":"105263783 CCR4-NOT transcription complex subunit 2 isoform X1\tK12605 CNOT2; CCR4-NOT transcription complex subunit 2"
					},
					{
						"name":"105271887 CCR4-NOT transcription complex subunit 3 isoform X1\tK12580 CNOT3; CCR4-NOT transcription complex subunit 3"
					},
					{
						"name":"105271397 ras guanine nucleotide exchange factor R\tK10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]"
					},
					{
						"name":"105266575 CCR4-NOT transcription complex subunit 6-like isoform X1\tK12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]"
					},
					{
						"name":"105264498 CCR4-NOT transcription complex subunit 7 isoform X1\tK12581 CNOT7_8; CCR4-NOT transcription complex subunit 7\/8"
					},
					{
						"name":"105273930 DIS3-like exonuclease 2\tK18758 DIS3L2; DIS3-like exonuclease 2 [EC:3.1.13.-]"
					},
					{
						"name":"105264951 PAB-dependent poly(A)-specific ribonuclease subunit PAN2 isoform X1\tK12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4]"
					},
					{
						"name":"105264796 PAB-dependent poly(A)-specific ribonuclease subunit PAN3\tK12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3"
					},
					{
						"name":"105269827 protein Tob1-like\tK14443 TOB; protein Tob\/BTG"
					},
					{
						"name":"105273616 LOW QUALITY PROTEIN: protein BTG2-like\tK14443 TOB; protein Tob\/BTG"
					},
					{
						"name":"105267904 eukaryotic translation initiation factor 4E transporter isoform X1\tK18728 EIF4ENIF1; eukaryotic translation initiation factor 4E transporter"
					},
					{
						"name":"105264317 protein PAT1 homolog 1\tK12617 PATL1; DNA topoisomerase 2-associated protein PAT1"
					},
					{
						"name":"105264565 enhancer of mRNA-decapping protein 3-like\tK12615 EDC3; enhancer of mRNA-decapping protein 3"
					},
					{
						"name":"105266389 enhancer of mRNA-decapping protein 4\tK12616 EDC4; enhancer of mRNA-decapping protein 4"
					},
					{
						"name":"105273934 regulator of nonsense transcripts 2\tK14327 UPF2; regulator of nonsense transcripts 2"
					},
					{
						"name":"105267078 LOW QUALITY PROTEIN: regulator of nonsense transcripts 3A\tK14328 UPF3; regulator of nonsense transcripts 3"
					},
					{
						"name":"105266449 E3 ubiquitin-protein ligase TRIM71 isoform X1\tK12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]"
					},
					{
						"name":"105267294 DNA-directed RNA polymerase II subunit RPB7\tK03015 RPB7; DNA-directed RNA polymerase II subunit RPB7"
					},
					{
						"name":"105263541 YTH domain-containing family protein 3\tK20102 YTHDF; YTH domain-containing family protein"
					}
					]
				},
				{
					"name":"Stress granule specific factors",
					"children":[
					{
						"name":"105262860 nucleolysin TIAR isoform X1\tK13201 TIA1; nucleolysin TIA-1\/TIAR"
					},
					{
						"name":"105270287 nucleolysin TIAR\tK13201 TIA1; nucleolysin TIA-1\/TIAR"
					},
					{
						"name":"105263546 polyadenylate-binding protein\tK13126 PABPC; polyadenylate-binding protein"
					},
					{
						"name":"105263481 double-stranded RNA-binding protein Staufen homolog 2 isoform X1\tK17597 STAU; double-stranded RNA-binding protein Staufen"
					},
					{
						"name":"105263346 fragile X mental retardation syndrome-related protein 1 isoform X1\tK15516 FMR; fragile X mental retardation protein"
					},
					{
						"name":"105266506 ras GTPase-activating protein-binding protein 2\tK24983 G3BP2; Ras GTPase-activating protein-binding protein 2"
					},
					{
						"name":"105271631 eukaryotic translation initiation factor 2A\tK15026 EIF2A; translation initiation factor 2A"
					},
					{
						"name":"105266240 eukaryotic translation initiation factor 3 subunit B\tK03253 EIF3B; translation initiation factor 3 subunit B"
					},
					{
						"name":"105268345 eukaryotic initiation factor 4A\tK03257 EIF4A; translation initiation factor 4A"
					},
					{
						"name":"105266767 eukaryotic initiation factor 4A-III\tK13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7]"
					},
					{
						"name":"105270646 eukaryotic translation initiation factor 4B-like\tK03258 EIF4B; translation initiation factor 4B"
					},
					{
						"name":"105263601 eukaryotic translation initiation factor 4 gamma 2 isoform X1\tK03260 EIF4G; translation initiation factor 4G"
					},
					{
						"name":"105268546 eukaryotic translation initiation factor 4 gamma 3-like isoform X1\tK03260 EIF4G; translation initiation factor 4G"
					},
					{
						"name":"105271600 ribosomal protein S6 kinase 2 beta\tK04373 RPS6KA; ribosomal protein S6 kinase alpha-1\/2\/3\/6 [EC:2.7.11.1]"
					},
					{
						"name":"105265815 guanine nucleotide-binding protein subunit beta-like protein isoform X1\tK14753 RACK1; guanine nucleotide-binding protein subunit beta-2-like 1 protein"
					},
					{
						"name":"105263202 nuclear RNA export factor 1-like\tK14284 NXF; nuclear RNA export factor"
					},
					{
						"name":"105265120 nuclear RNA export factor 1-like\tK14284 NXF; nuclear RNA export factor"
					},
					{
						"name":"105271346 histone deacetylase 6 isoform X1\tK11407 HDAC6; histone deacetylase 6 [EC:3.5.1.98]"
					},
					{
						"name":"105263249 tudor domain-containing protein 3\tK18404 TDRD3; tudor domain-containing protein 3"
					},
					{
						"name":"105264295 la-related protein CG11505 isoform X1\tK18763 LARP4; la-related protein 4"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"mRNA degradation factors",
			"children":[
			{
				"name":"5'-3' decay",
				"children":[
				{
					"name":"Decapping complex",
					"children":[
					{
						"name":"105273826 mRNA-decapping enzyme 1A\tK12611 DCP1B; mRNA-decapping enzyme 1B [EC:3.-.-.-]"
					},
					{
						"name":"105264168 m7GpppN-mRNA hydrolase isoform X1\tK12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62]"
					},
					{
						"name":"105274280 putative ATP-dependent RNA helicase me31b\tK12614 DDX6; ATP-dependent RNA helicase DDX6\/DHH1 [EC:5.6.2.7]"
					},
					{
						"name":"105264565 enhancer of mRNA-decapping protein 3-like\tK12615 EDC3; enhancer of mRNA-decapping protein 3"
					},
					{
						"name":"105266389 enhancer of mRNA-decapping protein 4\tK12616 EDC4; enhancer of mRNA-decapping protein 4"
					},
					{
						"name":"105264317 protein PAT1 homolog 1\tK12617 PATL1; DNA topoisomerase 2-associated protein PAT1"
					}
					]
				},
				{
					"name":"Lsm complex",
					"children":[
					{
						"name":"105263987 U6 snRNA-associated Sm-like protein LSm1\tK12620 LSM1; U6 snRNA-associated Sm-like protein LSm1"
					},
					{
						"name":"105268660 U6 snRNA-associated Sm-like protein LSm2\tK12621 LSM2; U6 snRNA-associated Sm-like protein LSm2"
					},
					{
						"name":"105266108 U6 snRNA-associated Sm-like protein LSm3\tK12622 LSM3; U6 snRNA-associated Sm-like protein LSm3"
					},
					{
						"name":"105266954 U6 snRNA-associated Sm-like protein LSm4\tK12623 LSM4; U6 snRNA-associated Sm-like protein LSm4"
					},
					{
						"name":"105274117 U6 snRNA-associated Sm-like protein LSm5 isoform X1\tK12624 LSM5; U6 snRNA-associated Sm-like protein LSm5"
					},
					{
						"name":"105264644 U6 snRNA-associated Sm-like protein LSm6\tK12625 LSM6; U6 snRNA-associated Sm-like protein LSm6"
					},
					{
						"name":"105270460 U6 snRNA-associated Sm-like protein LSm7\tK12626 LSM7; U6 snRNA-associated Sm-like protein LSm7"
					},
					{
						"name":"105270915 U6 snRNA-associated Sm-like protein LSm8\tK12627 LSM8; U6 snRNA-associated Sm-like protein LSm8"
					}
					]
				},
				{
					"name":"5' exonucleases",
					"children":[
					{
						"name":"105269019 5'-3' exoribonuclease 1\tK12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]"
					},
					{
						"name":"105271811 5'-3' exoribonuclease 2 homolog\tK12619 XRN2; 5'-3' exoribonuclease 2 [EC:3.1.13.-]"
					}
					]
				},
				{
					"name":"Other 5'-3' decay factors",
					"children":[
					{
						"name":"105273354 m7GpppX diphosphatase\tK12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59]"
					},
					{
						"name":"105268724 probable helicase with zinc finger domain\tK25168 HELZ; helicase with zinc finger domain [EC:5.6.2.-]"
					}
					]
				}
				]
			},
			{
				"name":"3'-5' decay",
				"children":[
				{
					"name":"Core exosome factors",
					"children":[
					{
						"name":"105273973 exosome complex component CSL4 isoform X1\tK07573 CSL4; exosome complex component CSL4"
					},
					{
						"name":"105267346 exosome complex component RRP4\tK03679 RRP4; exosome complex component RRP4"
					},
					{
						"name":"105268420 exosome complex component RRP40\tK03681 RRP40; exosome complex component RRP40"
					},
					{
						"name":"105269324 exosome complex component RRP41\tK11600 RRP41; exosome complex component RRP41"
					},
					{
						"name":"105269202 exosome complex component RRP46\tK12590 RRP46; exosome complex component RRP46"
					},
					{
						"name":"105264335 exosome complex component MTR3\tK12587 MTR3; exosome complex component MTR3"
					},
					{
						"name":"105268492 exosome complex exonuclease RRP42 isoform X1\tK12589 RRP42; exosome complex component RRP42"
					},
					{
						"name":"105271489 exosome complex component RRP43-like\tK12586 RRP43; exosome complex component RRP43"
					},
					{
						"name":"105271500 exosome complex component rrp45\tK03678 RRP45; exosome complex component RRP45"
					}
					]
				},
				{
					"name":"Exosome cofactors",
					"children":[
					{
						"name":"105263665 exosome complex exonuclease RRP44\tK12585 DIS3; exosome complex exonuclease DIS3\/RRP44 [EC:3.1.13.-]"
					},
					{
						"name":"105265851 exosome component 10\tK12591 RRP6; exosome complex exonuclease RRP6 [EC:3.1.13.-]"
					},
					{
						"name":"105266220 nuclear nucleic acid-binding protein C1D-like\tK12592 C1D; exosome complex protein LRP1"
					},
					{
						"name":"105264432 M-phase phosphoprotein 6 isoform X1\tK12593 MPHOSPH6; M-phase phosphoprotein 6, animal type"
					}
					]
				},
				{
					"name":"TRAMP complex",
					"children":[
					{
						"name":"105264343 non-canonical poly(A) RNA polymerase PAPD5-like isoform X1\tK03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5\/7 [EC:2.7.7.19]"
					},
					{
						"name":"105263661 superkiller viralicidic activity 2-like 2\tK12598 MTR4; ATP-dependent RNA helicase DOB1 [EC:5.6.2.6]"
					}
					]
				},
				{
					"name":"Ski complex",
					"children":[
					{
						"name":"105268330 helicase SKI2W\tK12599 SKI2; antiviral helicase SKI2 [EC:5.6.2.6]"
					},
					{
						"name":"105265451 tetratricopeptide repeat protein 37\tK12600 SKI3; superkiller protein 3"
					},
					{
						"name":"105264033 WD repeat-containing protein 61\tK12602 WDR61; WD repeat-containing protein 61"
					}
					]
				},
				{
					"name":"Ccr4-NOT complex",
					"children":[
					{
						"name":"105266575 CCR4-NOT transcription complex subunit 6-like isoform X1\tK12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]"
					},
					{
						"name":"105270081 CCR4-NOT transcription complex subunit 1\tK12604 CNOT1; CCR4-NOT transcription complex subunit 1"
					},
					{
						"name":"105263783 CCR4-NOT transcription complex subunit 2 isoform X1\tK12605 CNOT2; CCR4-NOT transcription complex subunit 2"
					},
					{
						"name":"105271887 CCR4-NOT transcription complex subunit 3 isoform X1\tK12580 CNOT3; CCR4-NOT transcription complex subunit 3"
					},
					{
						"name":"105271397 ras guanine nucleotide exchange factor R\tK10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]"
					},
					{
						"name":"105264498 CCR4-NOT transcription complex subunit 7 isoform X1\tK12581 CNOT7_8; CCR4-NOT transcription complex subunit 7\/8"
					},
					{
						"name":"105268956 cell differentiation protein RCD1 homolog\tK12606 RCD1; CCR4-NOT transcription complex subunit 9"
					},
					{
						"name":"105272387 CCR4-NOT transcription complex subunit 10\tK12607 CNOT10; CCR4-NOT transcription complex subunit 10"
					}
					]
				},
				{
					"name":"Pan complex",
					"children":[
					{
						"name":"105264951 PAB-dependent poly(A)-specific ribonuclease subunit PAN2 isoform X1\tK12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4]"
					},
					{
						"name":"105264796 PAB-dependent poly(A)-specific ribonuclease subunit PAN3\tK12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3"
					}
					]
				},
				{
					"name":"Other 3'-5' decay factors",
					"children":[
					{
						"name":"105268464 poly(A)-specific ribonuclease PARN-like domain-containing protein 1 isoform X1\tK01148 PARN; poly(A)-specific ribonuclease [EC:3.1.13.4]"
					},
					{
						"name":"105269697 poly(A)-specific ribonuclease PARN-like isoform X1\tK01148 PARN; poly(A)-specific ribonuclease [EC:3.1.13.4]"
					},
					{
						"name":"105267433 ATP-dependent RNA helicase DHX36\tK14442 DHX36; ATP-dependent RNA helicase DHX36 [EC:5.6.2.6]"
					},
					{
						"name":"105269827 protein Tob1-like\tK14443 TOB; protein Tob\/BTG"
					},
					{
						"name":"105273616 LOW QUALITY PROTEIN: protein BTG2-like\tK14443 TOB; protein Tob\/BTG"
					},
					{
						"name":"105273354 m7GpppX diphosphatase\tK12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59]"
					},
					{
						"name":"105272840 2',5'-phosphodiesterase 12 isoform X1\tK19612 PDE12; 2',5'-phosphodiesterase [EC:3.1.13.4 3.1.4.-]"
					},
					{
						"name":"105268724 probable helicase with zinc finger domain\tK25168 HELZ; helicase with zinc finger domain [EC:5.6.2.-]"
					},
					{
						"name":"105266313 protein NRDE2 homolog\tK26109 NRDE2; nuclear exosome regulator NRDE2"
					},
					{
						"name":"105265373 protein Smaug homolog 1\tK27396 SMG; protein Smaug"
					},
					{
						"name":"105273702 focadhesin\tK27498 FOCAD; focadhesin"
					}
					]
				}
				]
			},
			{
				"name":"Other degradation factors",
				"children":[
				{
					"name":"RNases",
					"children":[
					{
						"name":"105267796 ribonuclease ZC3H12A isoform X1\tK18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]"
					}
					]
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic type",
		"children":[
		{
			"name":"Bacterial mRNA degradation factors",
			"children":[
			{
				"name":"RNA degradosome components",
				"children":[
				{
					"name":"Ribonucreases",
					"children":[
					{
						"name":"105266152 ribonuclease 3\tK03685 rnc; ribonuclease III [EC:3.1.26.3]"
					}
					]
				},
				{
					"name":"Helicases"
				},
				{
					"name":"Other RNA degradosome components",
					"children":[
					{
						"name":"105272607 enolase\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]"
					},
					{
						"name":"105273444 enolase-like\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]"
					},
					{
						"name":"105268247 polyribonucleotide nucleotidyltransferase 1, mitochondrial\tK00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]"
					},
					{
						"name":"105264157 ATP-dependent 6-phosphofructokinase isoform X1\tK00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]"
					}
					]
				}
				]
			},
			{
				"name":"Other RNA degradation factors",
				"children":[
				{
					"name":"Chaperones",
					"children":[
					{
						"name":"105263971 heat shock 70 kDa protein cognate 5\tK04043 dnaK; molecular chaperone DnaK"
					},
					{
						"name":"105265728 60 kDa heat shock protein, mitochondrial-like\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
					}
					]
				},
				{
					"name":"Others"
				},
				{
					"name":"Bacterial Small RNA Regulators"
				}
				]
			}
			]
		},
		{
			"name":"Archeal mRNA degradation factors",
			"children":[
			{
				"name":"Exosome components",
				"children":[
				{
					"name":"Core exosome",
					"children":[
					{
						"name":"105267346 exosome complex component RRP4\tK03679 RRP4; exosome complex component RRP4"
					},
					{
						"name":"105273973 exosome complex component CSL4 isoform X1\tK07573 CSL4; exosome complex component CSL4"
					}
					]
				},
				{
					"name":"Cofactors",
					"children":[
					{
						"name":"105269324 exosome complex component RRP41\tK11600 RRP41; exosome complex component RRP41"
					},
					{
						"name":"105268492 exosome complex exonuclease RRP42 isoform X1\tK12589 RRP42; exosome complex component RRP42"
					}
					]
				},
				{
					"name":"Others"
				}
				]
			}
			]
		}
		]
	}
	]
}