{
	"name":"fcy03400",
	"children":[
	{
		"name":"Eukaryotic type",
		"children":[
		{
			"name":"SSBR (single strand breaks repair)",
			"children":[
			{
				"name":"Direct repair",
				"children":[
				{
					"name":"FRACYDRAFT_169804 Sec63-domain-containing protein\tK18663 ASCC3; activating signal cointegrator complex subunit 3 [EC:5.6.2.4]"
				},
				{
					"name":"FRACYDRAFT_158036 CPD3a; FAD_binding_7-domain-containing protein\tK01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]"
				}
				]
			},
			{
				"name":"BER (base exicision repair)",
				"children":[
				{
					"name":"DNA glycosylases",
					"children":[
					{
						"name":"FRACYDRAFT_208373 UngB; uracil-DNA glycosylase\tK03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]"
					},
					{
						"name":"FRACYDRAFT_227821 UngA_1; uracil-DNA glycosylase\tK03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]"
					},
					{
						"name":"FRACYDRAFT_187316 MutY_a; DNA glycosylase\tK03575 mutY; A\/G-specific adenine glycosylase [EC:3.2.2.31]"
					},
					{
						"name":"FRACYDRAFT_186086 Ogg_a; DNA glycosylase\tK03660 OGG1; N-glycosylase\/DNA lyase [EC:3.2.2.- 4.2.99.18]"
					},
					{
						"name":"FRACYDRAFT_225447 hypothetical protein\tK10569 NEIL3; endonuclease VIII-like 3 [EC:3.2.2.- 4.2.99.18]"
					},
					{
						"name":"FRACYDRAFT_160865 DNA glycosylase\tK10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]"
					},
					{
						"name":"FRACYDRAFT_161186 EndoIII-related_a; DNA glycosylase\tK10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]"
					},
					{
						"name":"FRACYDRAFT_162373 EndoIIIa; DNA glycosylase\tK10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]"
					}
					]
				},
				{
					"name":"AP endonucleases"
				},
				{
					"name":"Long Patch-BER factors",
					"children":[
					{
						"name":"DNA polymerase delta complex",
						"children":[
						{
							"name":"FRACYDRAFT_180847 DNA polymerase delta catalytic subunit\tK02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]"
						},
						{
							"name":"FRACYDRAFT_138278 DNA_pol_E_B-domain-containing protein\tK02328 POLD2; DNA polymerase delta subunit 2"
						}
						]
					},
					{
						"name":"DNA polymerase epsilon complex",
						"children":[
						{
							"name":"FRACYDRAFT_189483 DNA\/RNA polymerase\tK02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]"
						},
						{
							"name":"FRACYDRAFT_235118 PolE; DNA_pol_E_B-domain-containing protein\tK02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]"
						},
						{
							"name":"FRACYDRAFT_164395 hypothetical protein\tK02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]"
						}
						]
					},
					{
						"name":"FRACYDRAFT_191550 PCNA1; proliferating cell nuclear antigen\tK04802 PCNA; proliferating cell nuclear antigen"
					},
					{
						"name":"FRACYDRAFT_206746 FEN-1; PIN domain-like protein\tK04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]"
					},
					{
						"name":"FRACYDRAFT_225386 Lig1_a; ATP-dependent DNA ligase\tK10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]"
					}
					]
				},
				{
					"name":"Short Patch-BER factors"
				},
				{
					"name":"Other BER factors",
					"children":[
					{
						"name":"FRACYDRAFT_190809 phospholipase D\/nuclease\tK10862 TDP1; tyrosyl-DNA phosphodiesterase 1 [EC:3.1.4.-]"
					}
					]
				}
				]
			},
			{
				"name":"NER (nucleotide excision repair)",
				"children":[
				{
					"name":"GGR (global genome repair) factors",
					"children":[
					{
						"name":"XPC-HR23B-CETN2 complex",
						"children":[
						{
							"name":"FRACYDRAFT_227534 hypothetical protein\tK10838 XPC; xeroderma pigmentosum group C-complementing protein"
						},
						{
							"name":"FRACYDRAFT_208711 Rad23B; XPC-binding-domain-containing protein\tK10839 RAD23; UV excision repair protein RAD23"
						}
						]
					},
					{
						"name":"Cul4-DDB2 complex",
						"children":[
						{
							"name":"FRACYDRAFT_206499 ring-box protein\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
						},
						{
							"name":"FRACYDRAFT_135945 DDB1_1; CPSF_A-domain-containing protein\tK10610 DDB1; DNA damage-binding protein 1"
						}
						]
					},
					{
						"name":"NER4 complex",
						"children":[
						{
							"name":"FRACYDRAFT_209064 SNF2_N-domain-containing protein\tK15083 RAD16; DNA repair protein RAD16"
						}
						]
					}
					]
				},
				{
					"name":"TCR (transcription coupled repair) factors",
					"children":[
					{
						"name":"DNA-directed RNA polymerase II complex",
						"children":[
						{
							"name":"FRACYDRAFT_183150 RNA_pol; putative DNA-dependent RNA polymerase\tK03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]"
						},
						{
							"name":"FRACYDRAFT_174108 RNA polymerase II second largest subunit\tK03010 RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]"
						},
						{
							"name":"FRACYDRAFT_267685 insert subdomain of RNA polymerase alpha subunit\tK03011 RPB3; DNA-directed RNA polymerase II subunit RPB3"
						},
						{
							"name":"FRACYDRAFT_275138 hypothetical protein\tK03012 RPB4; DNA-directed RNA polymerase II subunit RPB4"
						},
						{
							"name":"FRACYDRAFT_271383 RPB5 subunit of DNA-directed RNA polymerase\tK03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1"
						},
						{
							"name":"FRACYDRAFT_194432 RNA polymerase Rpb6\tK03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2"
						},
						{
							"name":"FRACYDRAFT_181715 hypothetical protein\tK03015 RPB7; DNA-directed RNA polymerase II subunit RPB7"
						},
						{
							"name":"FRACYDRAFT_268152 RNA polymerase\tK03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3"
						},
						{
							"name":"FRACYDRAFT_177662 hypothetical protein\tK03017 RPB9; DNA-directed RNA polymerase II subunit RPB9"
						},
						{
							"name":"FRACYDRAFT_193447 DNA-directed RNA polymerases I, II, and III subunit rpabc5\tK03007 RPABC5; DNA-directed RNA polymerases I, II, and III subunit RPABC5"
						},
						{
							"name":"FRACYDRAFT_224004 hypothetical protein\tK03008 RPB11; DNA-directed RNA polymerase II subunit RPB11"
						}
						]
					},
					{
						"name":"Cul4-CSA complex",
						"children":[
						{
							"name":"FRACYDRAFT_206499 ring-box protein\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
						},
						{
							"name":"FRACYDRAFT_135945 DDB1_1; CPSF_A-domain-containing protein\tK10610 DDB1; DNA damage-binding protein 1"
						},
						{
							"name":"FRACYDRAFT_232933 CSA; WD40 repeat-like protein\tK10570 ERCC8; DNA excision repair protein ERCC-8"
						}
						]
					},
					{
						"name":"Other TCR factor",
						"children":[
						{
							"name":"FRACYDRAFT_181318 CSB; SNF2_N-domain-containing protein\tK10841 ERCC6; DNA excision repair protein ERCC-6"
						},
						{
							"name":"FRACYDRAFT_165256 Elf1-domain-containing protein\tK25829 ELOF1; transcription elongation factor 1"
						}
						]
					}
					]
				},
				{
					"name":"TFIIH complex",
					"children":[
					{
						"name":"FRACYDRAFT_177977 XPB_1; DNA excision repair cross-complementing protein\tK10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]"
					},
					{
						"name":"FRACYDRAFT_191543 XPD_1; DNA repair helicase\tK10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]"
					},
					{
						"name":"FRACYDRAFT_178730 hypothetical protein\tK03141 TFIIH1; transcription initiation factor TFIIH subunit 1"
					},
					{
						"name":"FRACYDRAFT_138893 Ssl1-domain-containing protein\tK03142 TFIIH2; transcription initiation factor TFIIH subunit 2"
					},
					{
						"name":"FRACYDRAFT_193684 hypothetical protein\tK03143 TFIIH3; transcription initiation factor TFIIH subunit 3"
					},
					{
						"name":"FRACYDRAFT_182101 Tfb2-domain-containing protein\tK03144 TFIIH4; transcription initiation factor TFIIH subunit 4"
					},
					{
						"name":"FRACYDRAFT_237737 hypothetical protein\tK10845 TTDA; TFIIH basal transcription factor complex TTD-A subunit"
					},
					{
						"name":"FRACYDRAFT_226143 CDKD1; cell division protein kinase\tK02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]"
					},
					{
						"name":"FRACYDRAFT_217329 hypothetical protein\tK06634 CCNH; cyclin H"
					},
					{
						"name":"FRACYDRAFT_267725 hypothetical protein\tK10842 MNAT1; CDK-activating kinase assembly factor MAT1"
					}
					]
				},
				{
					"name":"RPA (replication factor A)",
					"children":[
					{
						"name":"FRACYDRAFT_211019 RPA1a; replication factor-a protein\tK07466 RFA1; replication factor A1"
					},
					{
						"name":"FRACYDRAFT_209072 Rpa2a; replication protein A, subunit RPA32\tK10739 RFA2; replication factor A2"
					}
					]
				},
				{
					"name":"Other NER factors",
					"children":[
					{
						"name":"FRACYDRAFT_181618 ERCC1; DNA repair protein rad10\tK10849 ERCC1; DNA excision repair protein ERCC-1"
					},
					{
						"name":"FRACYDRAFT_208467 hypothetical protein\tK10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]"
					},
					{
						"name":"FRACYDRAFT_225386 Lig1_a; ATP-dependent DNA ligase\tK10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]"
					},
					{
						"name":"FRACYDRAFT_139902 WD40 repeat-like protein\tK24730 CIAO1; cytosolic iron-sulfur protein assembly protein CIAO1"
					},
					{
						"name":"FRACYDRAFT_163527 hypothetical protein\tK26403 CIAO2; cytosolic iron-sulfur assembly component 2"
					},
					{
						"name":"FRACYDRAFT_169868 Cullin-domain-containing protein\tK03869 CUL3; cullin 3"
					},
					{
						"name":"FRACYDRAFT_218071 putative transcription elongation factor B polypeptide 1\tK03872 ELOC; elongin-C"
					}
					]
				}
				]
			},
			{
				"name":"MMR (mismatch excision repair)",
				"children":[
				{
					"name":"Mismatch and loop recognition factors",
					"children":[
					{
						"name":"FRACYDRAFT_157228 MSH2_a; MutS_V-domain-containing protein\tK08735 MSH2; DNA mismatch repair protein MSH2"
					},
					{
						"name":"FRACYDRAFT_212924 MSH6; MutS_V-domain-containing protein\tK08737 MSH6; DNA mismatch repair protein MSH6"
					}
					]
				},
				{
					"name":"MutL homologs",
					"children":[
					{
						"name":"FRACYDRAFT_136590 hypothetical protein\tK08734 MLH1; DNA mismatch repair protein MLH1"
					},
					{
						"name":"FRACYDRAFT_212051 hypothetical protein\tK10858 PMS2; DNA mismatch repair protein PMS2"
					}
					]
				},
				{
					"name":"DNA polymerase delta complex",
					"children":[
					{
						"name":"FRACYDRAFT_180847 DNA polymerase delta catalytic subunit\tK02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]"
					},
					{
						"name":"FRACYDRAFT_138278 DNA_pol_E_B-domain-containing protein\tK02328 POLD2; DNA polymerase delta subunit 2"
					}
					]
				},
				{
					"name":"RPA (replication factor A)",
					"children":[
					{
						"name":"FRACYDRAFT_211019 RPA1a; replication factor-a protein\tK07466 RFA1; replication factor A1"
					},
					{
						"name":"FRACYDRAFT_209072 Rpa2a; replication protein A, subunit RPA32\tK10739 RFA2; replication factor A2"
					}
					]
				},
				{
					"name":"RFC (replication factor C)",
					"children":[
					{
						"name":"FRACYDRAFT_178496 Rfc1a; RFC1-domain-containing protein\tK10754 RFC1; replication factor C subunit 1"
					},
					{
						"name":"FRACYDRAFT_196471 Rfc4a; P-loop containing nucleoside triphosphate hydrolase protein\tK10755 RFC2_4; replication factor C subunit 2\/4"
					},
					{
						"name":"FRACYDRAFT_207120 Rfc2; P-loop containing nucleoside triphosphate hydrolase protein\tK10755 RFC2_4; replication factor C subunit 2\/4"
					},
					{
						"name":"FRACYDRAFT_187556 Rfc3a; replication factor C 3\tK10756 RFC3_5; replication factor C subunit 3\/5"
					},
					{
						"name":"FRACYDRAFT_274639 hypothetical protein\tK10756 RFC3_5; replication factor C subunit 3\/5"
					}
					]
				},
				{
					"name":"Other MMR factors",
					"children":[
					{
						"name":"FRACYDRAFT_191550 PCNA1; proliferating cell nuclear antigen\tK04802 PCNA; proliferating cell nuclear antigen"
					},
					{
						"name":"FRACYDRAFT_261553 EXO1_1; PIN domain-like protein\tK10746 EXO1; exonuclease 1 [EC:3.1.-.-]"
					},
					{
						"name":"FRACYDRAFT_225386 Lig1_a; ATP-dependent DNA ligase\tK10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"DSBR (double strand breaks repair)",
			"children":[
			{
				"name":"HR (homologous recombination)",
				"children":[
				{
					"name":"MRN(MRX) complex",
					"children":[
					{
						"name":"FRACYDRAFT_275781 Mre11a; DNA repair exonuclease\tK10865 MRE11; double-strand break repair protein MRE11"
					}
					]
				},
				{
					"name":"BRCA1-core complex"
				},
				{
					"name":"BRCA1-A complex"
				},
				{
					"name":"BRCA1-B complex",
					"children":[
					{
						"name":"FRACYDRAFT_236571 hypothetical protein\tK15362 BRIP1; fanconi anemia group J protein [EC:5.6.2.3]"
					}
					]
				},
				{
					"name":"BRCA1-C complex",
					"children":[
					{
						"name":"FRACYDRAFT_275781 Mre11a; DNA repair exonuclease\tK10865 MRE11; double-strand break repair protein MRE11"
					}
					]
				},
				{
					"name":"BRCA complex",
					"children":[
					{
						"name":"FRACYDRAFT_183976 BRCA2a; nucleic acid-binding protein\tK08775 BRCA2; breast cancer 2 susceptibility protein"
					}
					]
				},
				{
					"name":"RecA family proteins",
					"children":[
					{
						"name":"FRACYDRAFT_247629 hypothetical protein\tK10870 RAD51L2; RAD51-like protein 2"
					}
					]
				},
				{
					"name":"Rad52 family proteins",
					"children":[
					{
						"name":"FRACYDRAFT_183986 Rad52a; dsRNA-binding domain-like protein\tK10873 RAD52; DNA repair and recombination protein RAD52"
					}
					]
				},
				{
					"name":"Rad54 family proteins",
					"children":[
					{
						"name":"FRACYDRAFT_194223 Rad54_homologA; SNF2_N-domain-containing protein\tK10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]"
					},
					{
						"name":"FRACYDRAFT_259049 RAD54; putative DNA repair and recombination protein RAD54\tK10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]"
					}
					]
				},
				{
					"name":"RecQ family DNA helicases",
					"children":[
					{
						"name":"FRACYDRAFT_157933 DHC1; ATP-dependent DNA helicase\tK10899 RECQL; ATP-dependent DNA helicase Q1 [EC:5.6.2.4]"
					}
					]
				},
				{
					"name":"Bloom's syndrome complex (BTR)",
					"children":[
					{
						"name":"FRACYDRAFT_247872 Top3a_1; prokaryotic type I DNA topoisomerase\tK03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]"
					}
					]
				},
				{
					"name":"RPA (replication factor A)",
					"children":[
					{
						"name":"FRACYDRAFT_211019 RPA1a; replication factor-a protein\tK07466 RFA1; replication factor A1"
					},
					{
						"name":"FRACYDRAFT_209072 Rpa2a; replication protein A, subunit RPA32\tK10739 RFA2; replication factor A2"
					}
					]
				},
				{
					"name":"Protein phosphatase 4",
					"children":[
					{
						"name":"FRACYDRAFT_226787 Metallo-dependent phosphatase\tK15423 PPP4C; serine\/threonine-protein phosphatase 4 catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"FRACYDRAFT_241726 ARM repeat-containing protein\tK15424 PPP4R1; serine\/threonine-protein phosphatase 4 regulatory subunit 1"
					},
					{
						"name":"FRACYDRAFT_209177 DUF625-domain-containing protein\tK17491 SMEK; protein phosphatase 4 regulatory subunit 3"
					}
					]
				},
				{
					"name":"AP-5 complex"
				},
				{
					"name":"SMC5-SMC6 complex",
					"children":[
					{
						"name":"FRACYDRAFT_193562 P-loop containing nucleoside triphosphate hydrolase protein\tK22803 SMC5; structural maintenance of chromosomes protein 5"
					},
					{
						"name":"FRACYDRAFT_168857 P-loop containing nucleoside triphosphate hydrolase protein\tK22804 SMC6; structural maintenance of chromosomes protein 6"
					},
					{
						"name":"FRACYDRAFT_232273 hypothetical protein\tK22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]"
					},
					{
						"name":"FRACYDRAFT_241253 hypothetical protein\tK22825 NSMCE4; non-structural maintenance of chromosomes element 4"
					}
					]
				},
				{
					"name":"Other HR factors",
					"children":[
					{
						"name":"FRACYDRAFT_149334 hypothetical protein\tK20777 EXD2; exonuclease 3'-5' domain-containing protein 2 [EC:3.1.11.1]"
					},
					{
						"name":"FRACYDRAFT_251731 hypothetical protein\tK15078 SLX1; structure-specific endonuclease subunit SLX1 [EC:3.6.1.-]"
					},
					{
						"name":"FRACYDRAFT_136790 GEN-1; PIN domain-like protein\tK15338 GEN1; holliday junction resolvase GEN1\/YEN1 [EC:3.1.-.-]"
					},
					{
						"name":"FRACYDRAFT_146775 hypothetical protein\tK22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-]"
					},
					{
						"name":"FRACYDRAFT_138383 AAA-domain-containing protein\tK22766 FIGNL1; fidgetin-like protein 1 [EC:5.6.2.-]"
					},
					{
						"name":"FRACYDRAFT_160431 AAA-domain-containing protein\tK22766 FIGNL1; fidgetin-like protein 1 [EC:5.6.2.-]"
					},
					{
						"name":"FRACYDRAFT_189062 MCM-domain-containing protein\tK10737 MCM8; DNA helicase MCM8 [EC:5.6.2.4]"
					},
					{
						"name":"FRACYDRAFT_156569 MCM-domain-containing protein\tK10738 MCM9; DNA helicase MCM9 [EC:5.6.2.4]"
					},
					{
						"name":"FRACYDRAFT_233219 hypothetical protein\tK22685 WSS1; DNA-dependent metalloprotease WSS1 [EC:3.4.24.-]"
					}
					]
				}
				]
			},
			{
				"name":"NHEJ (non-homologous end-joining)",
				"children":[
				{
					"name":"DNA-PK complex",
					"children":[
					{
						"name":"FRACYDRAFT_235894 Ku70; SPOC domain-like protein\tK10884 XRCC6; ATP-dependent DNA helicase 2 subunit 1"
					},
					{
						"name":"FRACYDRAFT_240046 Ku80; SPOC domain-like protein\tK10885 XRCC5; ATP-dependent DNA helicase 2 subunit 2"
					}
					]
				},
				{
					"name":"MRX complex",
					"children":[
					{
						"name":"FRACYDRAFT_275781 Mre11a; DNA repair exonuclease\tK10865 MRE11; double-strand break repair protein MRE11"
					}
					]
				},
				{
					"name":"DNA Ligase 4 complex"
				},
				{
					"name":"X-family DNA polymerases"
				},
				{
					"name":"Other NHEJ factors",
					"children":[
					{
						"name":"FRACYDRAFT_233304 hypothetical protein\tK19619 TDP2; tyrosyl-DNA phosphodiesterase 2 [EC:3.1.4.-]"
					}
					]
				}
				]
			},
			{
				"name":"FA (Fanconi anemia) pathway",
				"children":[
				{
					"name":"FA core complex"
				},
				{
					"name":"FA core complex binding factors"
				},
				{
					"name":"Bloom's syndrome complex (BTR)",
					"children":[
					{
						"name":"FRACYDRAFT_247872 Top3a_1; prokaryotic type I DNA topoisomerase\tK03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]"
					}
					]
				},
				{
					"name":"FANCD2-I complex"
				},
				{
					"name":"Downstream FA components",
					"children":[
					{
						"name":"FRACYDRAFT_183976 BRCA2a; nucleic acid-binding protein\tK08775 BRCA2; breast cancer 2 susceptibility protein"
					},
					{
						"name":"FRACYDRAFT_236571 hypothetical protein\tK15362 BRIP1; fanconi anemia group J protein [EC:5.6.2.3]"
					}
					]
				},
				{
					"name":"Other FA pathway factors",
					"children":[
					{
						"name":"FRACYDRAFT_247629 hypothetical protein\tK10870 RAD51L2; RAD51-like protein 2"
					},
					{
						"name":"FRACYDRAFT_232623 hypothetical protein\tK11137 TELO2; telomere length regulation protein"
					}
					]
				}
				]
			},
			{
				"name":"Other DSBR factors",
				"children":[
				{
					"name":"Protein phosphatase 6",
					"children":[
					{
						"name":"FRACYDRAFT_224152 Metallo-dependent phosphatase\tK15498 PPP6C; serine\/threonine-protein phosphatase 6 catalytic subunit [EC:3.1.3.16]"
					}
					]
				},
				{
					"name":"Ubiquitin ligases"
				},
				{
					"name":"Others",
					"children":[
					{
						"name":"FRACYDRAFT_138445 WD40 repeat-like protein\tK23314 WRAP53; telomerase Cajal body protein 1"
					},
					{
						"name":"FRACYDRAFT_237847 WD40 repeat-like protein\tK24752 WDR70; WD repeat-containing protein 70"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"TLS (translesion DNA synthesis) factors",
			"children":[
			{
				"name":"Y-family DNA polymerases",
				"children":[
				{
					"name":"FRACYDRAFT_249724 PolI-a; DNA\/RNA polymerase\tK03509 POLH; DNA polymerase eta [EC:2.7.7.7]"
				},
				{
					"name":"FRACYDRAFT_194538 PolKa; DNA\/RNA polymerase\tK03511 POLK; DNA polymerase kappa [EC:2.7.7.7]"
				},
				{
					"name":"FRACYDRAFT_170374 hypothetical protein\tK03515 REV1; DNA repair protein REV1 [EC:2.7.7.-]"
				}
				]
			},
			{
				"name":"B-family DNA polymerases",
				"children":[
				{
					"name":"FRACYDRAFT_205435 PolZ; DNA\/RNA polymerase\tK02350 REV3L; DNA polymerase zeta [EC:2.7.7.7]"
				}
				]
			},
			{
				"name":"A-family DNA polymerase"
			},
			{
				"name":"Rad6 epistasis group",
				"children":[
				{
					"name":"FRACYDRAFT_223245 UBC1; ubiquitin conjugating protein\tK10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]"
				},
				{
					"name":"FRACYDRAFT_136653 SNF2_N-domain-containing protein\tK15505 RAD5; DNA repair protein RAD5 [EC:5.6.2.-]"
				},
				{
					"name":"FRACYDRAFT_274601 MMS2; UBC-like protein\tK10704 UBE2V; ubiquitin-conjugating enzyme E2 variant"
				},
				{
					"name":"FRACYDRAFT_196165 UBC-like protein\tK10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]"
				},
				{
					"name":"FRACYDRAFT_208158 ubiquitin-conjugating enzyme\tK10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]"
				}
				]
			},
			{
				"name":"Other TLS factors",
				"children":[
				{
					"name":"FRACYDRAFT_191550 PCNA1; proliferating cell nuclear antigen\tK04802 PCNA; proliferating cell nuclear antigen"
				},
				{
					"name":"FRACYDRAFT_162340 hypothetical protein\tK26957 GCNA; germ cell nuclear acidic protein"
				}
				]
			}
			]
		},
		{
			"name":"Check point factors",
			"children":[
			{
				"name":"Rad9-Hus1-Rad1 complex",
				"children":[
				{
					"name":"FRACYDRAFT_186987 hypothetical protein\tK10994 RAD9A; cell cycle checkpoint control protein RAD9A [EC:3.1.11.2]"
				},
				{
					"name":"FRACYDRAFT_234617 hypothetical protein\tK10903 HUS1; HUS1 checkpoint protein"
				}
				]
			},
			{
				"name":"HRAD17(Rad24)-RFC complex",
				"children":[
				{
					"name":"FRACYDRAFT_187552 Rad17a; P-loop containing nucleoside triphosphate hydrolase protein\tK06662 HRAD17; cell cycle checkpoint protein"
				},
				{
					"name":"FRACYDRAFT_196471 Rfc4a; P-loop containing nucleoside triphosphate hydrolase protein\tK10755 RFC2_4; replication factor C subunit 2\/4"
				},
				{
					"name":"FRACYDRAFT_207120 Rfc2; P-loop containing nucleoside triphosphate hydrolase protein\tK10755 RFC2_4; replication factor C subunit 2\/4"
				},
				{
					"name":"FRACYDRAFT_187556 Rfc3a; replication factor C 3\tK10756 RFC3_5; replication factor C subunit 3\/5"
				},
				{
					"name":"FRACYDRAFT_274639 hypothetical protein\tK10756 RFC3_5; replication factor C subunit 3\/5"
				}
				]
			},
			{
				"name":"Rad17-Mec3-Ddc1 complex"
			},
			{
				"name":"FPC (fork protection complex)",
				"children":[
				{
					"name":"FRACYDRAFT_197226 hypothetical protein\tK10997 TIMELESS; replication fork protection complex subunit TIMELESS\/Tof1\/Swi1"
				}
				]
			},
			{
				"name":"Triple T complex",
				"children":[
				{
					"name":"FRACYDRAFT_232623 hypothetical protein\tK11137 TELO2; telomere length regulation protein"
				},
				{
					"name":"FRACYDRAFT_236258 hypothetical protein\tK20403 TTI1; TELO2-interacting protein 1"
				}
				]
			},
			{
				"name":"BAG6-UBL4A-GET4 complex"
			},
			{
				"name":"SOSS complex"
			},
			{
				"name":"Other check point factors",
				"children":[
				{
					"name":"FRACYDRAFT_194899 ATM; kinase-like protein\tK04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]"
				},
				{
					"name":"FRACYDRAFT_170079 14-3-3 protein\tK06630 YWHAE; 14-3-3 protein epsilon"
				},
				{
					"name":"FRACYDRAFT_160166 kinase-like protein\tK06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]"
				},
				{
					"name":"FRACYDRAFT_261371 AAA-domain-containing protein\tK12196 VPS4; vacuolar protein-sorting-associated protein 4"
				}
				]
			}
			]
		},
		{
			"name":"Other factors with a suspected DNA repair function",
			"children":[
			{
				"name":"DNA polymerases",
				"children":[
				{
					"name":"FRACYDRAFT_232295 hypothetical protein\tK22761 PRIMPOL; DNA-directed primase\/polymerase protein [EC:2.7.7.102 2.7.7.7]"
				}
				]
			},
			{
				"name":"Nucleases",
				"children":[
				{
					"name":"FRACYDRAFT_185579 Snm1; DRMBL-domain-containing protein\tK15340 DCLRE1A; DNA cross-link repair 1A protein"
				}
				]
			},
			{
				"name":"Helicases",
				"children":[
				{
					"name":"FRACYDRAFT_205339 SNF2_N-domain-containing protein\tK20098 ERCC6L2; DNA excision repair protein ERCC-6-like 2 [EC:5.6.2.-]"
				}
				]
			},
			{
				"name":"PSO4 complex",
				"children":[
				{
					"name":"FRACYDRAFT_238709 WD40 repeat-like protein\tK10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]"
				},
				{
					"name":"FRACYDRAFT_269656 hypothetical protein\tK12860 CDC5L; pre-mRNA-splicing factor CDC5\/CEF1"
				},
				{
					"name":"FRACYDRAFT_243553 hypothetical protein\tK12861 BCAS2; pre-mRNA-splicing factor SPF27"
				},
				{
					"name":"FRACYDRAFT_258986 WD40 repeat-like protein\tK12862 PLRG1; pleiotropic regulator 1"
				}
				]
			},
			{
				"name":"Modulation of nucleotide pools",
				"children":[
				{
					"name":"FRACYDRAFT_181580 hypothetical protein\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]"
				},
				{
					"name":"FRACYDRAFT_271337 hypothetical protein\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]"
				},
				{
					"name":"FRACYDRAFT_185467 hypothetical protein\tK17816 NUDT1; 8-oxo-dGTP diphosphatase \/ 2-hydroxy-dATP diphosphatase [EC:3.6.1.55 3.6.1.56]"
				},
				{
					"name":"FRACYDRAFT_271952 dUTP diphosphatase\tK01520 dut; dUTP diphosphatase [EC:3.6.1.23]"
				},
				{
					"name":"FRACYDRAFT_260490 ribonucleoside-diphosphate reductase-like protein M1 chain\tK10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]"
				},
				{
					"name":"FRACYDRAFT_262579 Ribonuc_red_lgC-domain-containing protein\tK10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]"
				},
				{
					"name":"FRACYDRAFT_259821 RNR; ribonucleotide reductase\tK10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]"
				},
				{
					"name":"FRACYDRAFT_268008 ribonucleotide reductase\tK10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic type",
		"children":[
		{
			"name":"SSBR (single strand breaks repair)",
			"children":[
			{
				"name":"Direct repair",
				"children":[
				{
					"name":"FRACYDRAFT_158036 CPD3a; FAD_binding_7-domain-containing protein\tK01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]"
				}
				]
			},
			{
				"name":"BER (base exicision repair)",
				"children":[
				{
					"name":"DNA glycosylases",
					"children":[
					{
						"name":"FRACYDRAFT_208373 UngB; uracil-DNA glycosylase\tK03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]"
					},
					{
						"name":"FRACYDRAFT_227821 UngA_1; uracil-DNA glycosylase\tK03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]"
					},
					{
						"name":"FRACYDRAFT_187316 MutY_a; DNA glycosylase\tK03575 mutY; A\/G-specific adenine glycosylase [EC:3.2.2.31]"
					},
					{
						"name":"FRACYDRAFT_149688 hypothetical protein\tK10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]"
					},
					{
						"name":"FRACYDRAFT_160865 DNA glycosylase\tK10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]"
					},
					{
						"name":"FRACYDRAFT_161186 EndoIII-related_a; DNA glycosylase\tK10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]"
					},
					{
						"name":"FRACYDRAFT_162373 EndoIIIa; DNA glycosylase\tK10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]"
					}
					]
				},
				{
					"name":"AP endonucleases",
					"children":[
					{
						"name":"FRACYDRAFT_182071 APE1a; exodeoxyribonuclease III Xth\tK01142 xthA; exodeoxyribonuclease III [EC:3.1.11.2]"
					}
					]
				},
				{
					"name":"RecJ"
				},
				{
					"name":"DNA ligase"
				},
				{
					"name":"DNA polymerase I",
					"children":[
					{
						"name":"FRACYDRAFT_225788 DNA\/RNA polymerase\tK02335 polA; DNA polymerase I [EC:2.7.7.7]"
					}
					]
				}
				]
			},
			{
				"name":"NER (nucleotide excision repair)",
				"children":[
				{
					"name":"GGR (global genome repair) factors",
					"children":[
					{
						"name":"FRACYDRAFT_225788 DNA\/RNA polymerase\tK02335 polA; DNA polymerase I [EC:2.7.7.7]"
					}
					]
				},
				{
					"name":"TCR (transcription coupled repair) factors",
					"children":[
					{
						"name":"DNA-directed RNA polymerase complex (RNAP)"
					},
					{
						"name":"TRCF (transcription-repair coupling factor)"
					}
					]
				}
				]
			},
			{
				"name":"MMR (mismatch excision repair)",
				"children":[
				{
					"name":"Mismatch and loop recognition factors"
				},
				{
					"name":"Molecular matchmaker"
				},
				{
					"name":"Strand discrimination factor"
				},
				{
					"name":"DNA exonucleases"
				},
				{
					"name":"DNA polymerase III holoenzyme"
				},
				{
					"name":"DNA ligase"
				},
				{
					"name":"Other MMR factors"
				}
				]
			}
			]
		},
		{
			"name":"DSBR (double strand breaks repair)",
			"children":[
			{
				"name":"HR (homologous recombination)",
				"children":[
				{
					"name":"RecBC pathway proteins"
				},
				{
					"name":"RecFOR pathway proteins"
				},
				{
					"name":"AddAB pathway proteins"
				},
				{
					"name":"Other HR factor"
				},
				{
					"name":"Archaeal homologous recombinant proteins"
				}
				]
			},
			{
				"name":"NHEJ (non-homologous end-joining)",
				"children":[
				{
					"name":"Two-component NHEJ DNA repair complex"
				},
				{
					"name":"SHIIR (short-homology-independent illegitimate recombination)",
					"children":[
					{
						"name":"Facilitator",
						"children":[
						{
							"name":"FRACYDRAFT_265863 DNA gyrase\tK02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]"
						}
						]
					},
					{
						"name":"Supressor"
					}
					]
				},
				{
					"name":"SHDIR (short-homology-dependent illegitimate recombination)",
					"children":[
					{
						"name":"RecET pathway"
					},
					{
						"name":"Facilitator"
					},
					{
						"name":"Supressor",
						"children":[
						{
							"name":"FRACYDRAFT_183832 Wrna; ATP-dependent DNA helicase\tK03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]"
						}
						]
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"TLS (translesion DNA synthesis) factors",
			"children":[
			{
				"name":"Y-family DNA polymerases"
			},
			{
				"name":"Other SOS response factors"
			}
			]
		},
		{
			"name":"Other factors with a suspected DNA repair function",
			"children":[
			{
				"name":"DNA polymerase"
			},
			{
				"name":"DNA helicases"
			},
			{
				"name":"Modulation of nucleotide pools",
				"children":[
				{
					"name":"FRACYDRAFT_181580 hypothetical protein\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]"
				},
				{
					"name":"FRACYDRAFT_271337 hypothetical protein\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]"
				},
				{
					"name":"FRACYDRAFT_271952 dUTP diphosphatase\tK01520 dut; dUTP diphosphatase [EC:3.6.1.23]"
				}
				]
			},
			{
				"name":"Others"
			}
			]
		}
		]
	}
	]
}
