{
	"name":"fpg04121",
	"children":[
	{
		"name":"Ubiquitins and ubiquitin-like proteins",
		"children":[
		{
			"name":"Ubiquitins",
			"children":[
			{
				"name":"101912114 UBB; ubiquitin B\tK08770 UBB_C; ubiquitin B\/C"
			},
			{
				"name":"101921960 UBA52; ubiquitin A-52 residue ribosomal protein fusion product 1\tK02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e"
			},
			{
				"name":"101920481 RPS27A; ribosomal protein S27a\tK02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae"
			}
			]
		},
		{
			"name":"Ubiquitin-like proteins (UBLs)",
			"children":[
			{
				"name":"101912974 SUMO1; small ubiquitin-like modifier 1\tK12160 SUMO; small ubiquitin-related modifier"
			},
			{
				"name":"101924479 SUMO2; small ubiquitin-like modifier 2\tK12160 SUMO; small ubiquitin-related modifier"
			},
			{
				"name":"101910696 GABARAPL2; GABA type A receptor associated protein like 2\tK08341 GABARAP; GABA(A) receptor-associated protein"
			},
			{
				"name":"101919137 GABARAPL1; GABA type A receptor associated protein like 1\tK08341 GABARAP; GABA(A) receptor-associated protein"
			},
			{
				"name":"106112344 ATG12; autophagy related 12\tK08336 ATG12; ubiquitin-like protein ATG12"
			},
			{
				"name":"101914821 UFM1; ubiquitin fold modifier 1\tK12162 UFM1; ubiquitin-fold modifier 1"
			},
			{
				"name":"101918138 UBL3; ubiquitin like 3\tK28515 UBL3; membrane-anchored ubiquitin-fold protein"
			},
			{
				"name":"101910775 ZFAND4; zinc finger AN1-type containing 4\tK12163 ZFAND4; AN1-type zinc finger protein 4"
			}
			]
		}
		]
	},
	{
		"name":"Ubiquitin-activating enzymes (E1)",
		"children":[
		{
			"name":"Ubiquitin activating enzyme",
			"children":[
			{
				"name":"101918945 UBA7; ubiquitin like modifier activating enzyme 7\tK03178 UBE1; ubiquitin-activating enzyme E1 [EC:6.2.1.45]"
			},
			{
				"name":"101924506 UBA1; ubiquitin like modifier activating enzyme 1\tK03178 UBE1; ubiquitin-activating enzyme E1 [EC:6.2.1.45]"
			}
			]
		},
		{
			"name":"UBL-activating enzymes",
			"children":[
			{
				"name":"101917655 SAE1; SUMO1 activating enzyme subunit 1\tK10684 UBLE1A; ubiquitin-like 1-activating enzyme E1 A [EC:6.2.1.45]"
			},
			{
				"name":"101911547 UBA2; ubiquitin like modifier activating enzyme 2\tK10685 UBLE1B; ubiquitin-like 1-activating enzyme E1 B [EC:6.2.1.45]"
			},
			{
				"name":"101922859 UBA3; ubiquitin like modifier activating enzyme 3\tK10686 UBA3; NEDD8-activating enzyme E1 [EC:6.2.1.64]"
			},
			{
				"name":"101921307 NAE1; NEDD8 activating enzyme E1 subunit 1\tK04532 NAE1; NEDD8-activating enzyme E1 regulatory subunit"
			},
			{
				"name":"101918682 MOCS3; molybdenum cofactor synthesis 3\tK11996 MOCS3; adenylyltransferase and sulfurtransferase [EC:2.7.7.80 2.8.1.11]"
			},
			{
				"name":"101910830 UBA5; ubiquitin like modifier activating enzyme 5\tK12164 UBA5; ubiquitin-like modifier-activating enzyme 5"
			},
			{
				"name":"101924000 UBA6; ubiquitin like modifier activating enzyme 6\tK10699 UBE1L2; ubiquitin-activating enzyme E1-like protein 2 [EC:6.2.1.45]"
			},
			{
				"name":"101917711 ubiquitin-like modifier-activating enzyme ATG7\tK08337 ATG7; ubiquitin-like modifier-activating enzyme ATG7"
			}
			]
		}
		]
	},
	{
		"name":"Ubiquitin-conjugating enzymes (E2)",
		"children":[
		{
			"name":"Ubiquitin-conjugating enzymes",
			"children":[
			{
				"name":"101912173 UBE2A; ubiquitin conjugating enzyme E2 A\tK10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]"
			},
			{
				"name":"101911718 UBE2B; ubiquitin conjugating enzyme E2 B\tK10574 UBE2B; ubiquitin-conjugating enzyme E2 B [EC:2.3.2.23]"
			},
			{
				"name":"101911588 UBE2C; ubiquitin conjugating enzyme E2 C\tK06688 UBE2C; ubiquitin-conjugating enzyme E2 C [EC:2.3.2.23]"
			},
			{
				"name":"101914280 UBE2D3; ubiquitin conjugating enzyme E2 D3\tK06689 UBE2D; ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]"
			},
			{
				"name":"101915323 UBE2D1; ubiquitin conjugating enzyme E2 D1\tK06689 UBE2D; ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]"
			},
			{
				"name":"101919778 UBE2D2; ubiquitin conjugating enzyme E2 D2\tK06689 UBE2D; ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]"
			},
			{
				"name":"101922602 UBE2E3; ubiquitin conjugating enzyme E2 E3\tK20217 UBE2E; ubiquitin-conjugating enzyme E2 E [EC:2.3.2.23]"
			},
			{
				"name":"101922823 UBE2E2; ubiquitin-conjugating enzyme E2 E2\tK20217 UBE2E; ubiquitin-conjugating enzyme E2 E [EC:2.3.2.23]"
			},
			{
				"name":"101922999 UBE2E1; ubiquitin-conjugating enzyme E2 E1\tK20217 UBE2E; ubiquitin-conjugating enzyme E2 E [EC:2.3.2.23]"
			},
			{
				"name":"101924465 UBE2G1; ubiquitin conjugating enzyme E2 G1\tK10575 UBE2G1; ubiquitin-conjugating enzyme E2 G1 [EC:2.3.2.23]"
			},
			{
				"name":"101922540 UBE2G2; ubiquitin conjugating enzyme E2 G2\tK04555 UBE2G2; ubiquitin-conjugating enzyme E2 G2 [EC:2.3.2.23]"
			},
			{
				"name":"101910346 UBE2H; ubiquitin conjugating enzyme E2 H\tK10576 UBE2H; ubiquitin-conjugating enzyme E2 H [EC:2.3.2.23]"
			},
			{
				"name":"101924566 UBE2J1; ubiquitin conjugating enzyme E2 J1\tK10578 UBE2J1; ubiquitin-conjugating enzyme E2 J1 [EC:2.3.2.23]"
			},
			{
				"name":"101913033 UBE2J2; ubiquitin conjugating enzyme E2 J2\tK04554 UBE2J2; ubiquitin-conjugating enzyme E2 J2 [EC:2.3.2.23]"
			},
			{
				"name":"101912767 UBE2K; ubiquitin conjugating enzyme E2 K\tK04649 UBE2K; ubiquitin-conjugating enzyme (huntingtin interacting protein 2) [EC:2.3.2.23]"
			},
			{
				"name":"101914091 UBE2L3; ubiquitin conjugating enzyme E2 L3\tK04552 UBE2L3; ubiquitin-conjugating enzyme E2 L3 [EC:2.3.2.23]"
			},
			{
				"name":"101916776 ubiquitin-conjugating enzyme E2 L3-like\tK04552 UBE2L3; ubiquitin-conjugating enzyme E2 L3 [EC:2.3.2.23]"
			},
			{
				"name":"101915531 UBE2N; ubiquitin conjugating enzyme E2 N\tK10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]"
			},
			{
				"name":"101916974 UBE2O; ubiquitin conjugating enzyme E2 O\tK10581 UBE2O; ubiquitin-conjugating enzyme E2 O [EC:2.3.2.24]"
			},
			{
				"name":"101910701 UBE2Q1; ubiquitin conjugating enzyme E2 Q1\tK10582 UBE2Q; ubiquitin-conjugating enzyme E2 Q [EC:2.3.2.23]"
			},
			{
				"name":"101910943 UBE2QL1; ubiquitin conjugating enzyme E2 Q family like 1\tK10582 UBE2Q; ubiquitin-conjugating enzyme E2 Q [EC:2.3.2.23]"
			},
			{
				"name":"101923818 UBE2Q2; ubiquitin conjugating enzyme E2 Q2\tK10582 UBE2Q; ubiquitin-conjugating enzyme E2 Q [EC:2.3.2.23]"
			},
			{
				"name":"101922353 UBE2R2; ubiquitin conjugating enzyme E2 R2\tK02207 UBE2R; ubiquitin-conjugating enzyme E2 R [EC:2.3.2.23]"
			},
			{
				"name":"101924850 CDC34; cell division cycle 34\tK02207 UBE2R; ubiquitin-conjugating enzyme E2 R [EC:2.3.2.23]"
			},
			{
				"name":"101918118 UBE2T; ubiquitin conjugating enzyme E2 T\tK13960 UBE2T; ubiquitin-conjugating enzyme E2 T [EC:2.3.2.23]"
			},
			{
				"name":"101913697 UBE2W; ubiquitin conjugating enzyme E2 W\tK10688 UBE2W; ubiquitin-conjugating enzyme E2 W [EC:2.3.2.23 2.3.2.25]"
			},
			{
				"name":"101915911 UBE2Z; ubiquitin conjugating enzyme E2 Z\tK10585 UBE2Z; ubiquitin-conjugating enzyme E2 Z [EC:2.3.2.23]"
			},
			{
				"name":"101911521 BIRC6; baculoviral IAP repeat containing 6\tK10586 BIRC6; baculoviral IAP repeat-containing protein 6 (apollon) [EC:2.3.2.23]"
			}
			]
		},
		{
			"name":"UBL-conjugating enzymes",
			"children":[
			{
				"name":"101919668 UBE2I; ubiquitin conjugating enzyme E2 I\tK10577 UBE2I; ubiquitin-conjugating enzyme E2 I"
			},
			{
				"name":"101922503 UBE2F; ubiquitin conjugating enzyme E2 F (putative)\tK10687 UBE2F; ubiquitin-conjugating enzyme E2 F [EC:2.3.2.34]"
			},
			{
				"name":"101924990 UBE2M; ubiquitin conjugating enzyme E2 M\tK10579 UBE2M; ubiquitin-conjugating enzyme E2 M [EC:2.3.2.34]"
			},
			{
				"name":"101911210 ATG3; autophagy related 3\tK08343 ATG3; ubiquitin-like-conjugating enzyme ATG3"
			},
			{
				"name":"101913665 ATG10; autophagy related 10\tK17888 ATG10L; ubiquitin-like-conjugating enzyme ATG10"
			},
			{
				"name":"101910959 UFC1; ubiquitin-fold modifier conjugating enzyme 1\tK12165 UFC1; ufm1-conjugating enzyme 1"
			}
			]
		}
		]
	},
	{
		"name":"Ubiquitin ligases (E3)",
		"children":[
		{
			"name":"HECT type E3",
			"children":[
			{
				"name":"101919113 UBE3A; ubiquitin protein ligase E3A\tK10587 UBE3A; ubiquitin-protein ligase E3 A [EC:2.3.2.26]"
			},
			{
				"name":"101910355 UBE3B; ubiquitin protein ligase E3B\tK10588 UBE3B; ubiquitin-protein ligase E3 B [EC:2.3.2.26]"
			},
			{
				"name":"101912092 UBE3C; ubiquitin protein ligase E3C\tK10589 UBE3C; ubiquitin-protein ligase E3 C [EC:2.3.2.26]"
			},
			{
				"name":"101916690 UBE3D; ubiquitin protein ligase E3D\tK20803 UBE3D; ubiquitin-protein ligase E3 D [EC:2.3.2.26]"
			},
			{
				"name":"101918488 SMURF1; SMAD specific E3 ubiquitin protein ligase 1\tK04678 SMURF; E3 ubiquitin ligase SMURF1\/2 [EC:2.3.2.26]"
			},
			{
				"name":"101924223 SMURF2; SMAD specific E3 ubiquitin protein ligase 2\tK04678 SMURF; E3 ubiquitin ligase SMURF1\/2 [EC:2.3.2.26]"
			},
			{
				"name":"101923443 ITCH; itchy E3 ubiquitin protein ligase\tK05632 ITCH; E3 ubiquitin-protein ligase Itchy [EC:2.3.2.26]"
			},
			{
				"name":"101914676 WWP1; WW domain containing E3 ubiquitin protein ligase 1\tK05633 WWP1; NEDD4-like E3 ubiquitin-protein ligase WWP1 [EC:2.3.2.26]"
			},
			{
				"name":"101912384 WWP2; WW domain containing E3 ubiquitin protein ligase 2\tK05630 WWP2; NEDD4-like E3 ubiquitin-protein ligase WWP2 [EC:2.3.2.26]"
			},
			{
				"name":"101912160 TRIP12; thyroid hormone receptor interactor 12\tK10590 TRIP12; E3 ubiquitin-protein ligase TRIP12 [EC:2.3.2.26]"
			},
			{
				"name":"101919791 NEDD4L; neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase\tK13305 NEDD4L; E3 ubiquitin-protein ligase NEDD4-like [EC:2.3.2.26]"
			},
			{
				"name":"101911602 AREL1; apoptosis resistant E3 ubiquitin protein ligase 1\tK22370 AREL1; apoptosis-resistant E3 ubiquitin protein ligase 1 [EC:2.3.2.26]"
			},
			{
				"name":"101924544 UBR5; ubiquitin protein ligase E3 component n-recognin 5\tK10593 EDD1; E3 ubiquitin-protein ligase EDD1 [EC:2.3.2.26]"
			},
			{
				"name":"101924120 G2E3; G2\/M-phase specific E3 ubiquitin protein ligase\tK22371 G2H3; G2\/M phase-specific E3 ubiquitin-protein ligase [EC:2.3.2.26]"
			},
			{
				"name":"101923249 HERC1; HECT and RLD domain containing E3 ubiquitin protein ligase family member 1\tK10594 HERC1; E3 ubiquitin-protein ligase HERC1 [EC:2.3.2.26]"
			},
			{
				"name":"101920271 HERC2; HECT and RLD domain containing E3 ubiquitin protein ligase 2\tK10595 HERC2; E3 ubiquitin-protein ligase HERC2 [EC:2.3.2.26]"
			},
			{
				"name":"101912142 HERC3; HECT and RLD domain containing E3 ubiquitin protein ligase 3\tK10614 HERC3; E3 ubiquitin-protein ligase HERC3 [EC:2.3.2.26]"
			},
			{
				"name":"101920874 HERC4; HECT and RLD domain containing E3 ubiquitin protein ligase 4\tK10615 HERC4; E3 ubiquitin-protein ligase HERC4 [EC:2.3.2.26]"
			},
			{
				"name":"101919851 HACE1; HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1\tK12166 HACE1; E3 ubiquitin-protein ligase HACE1 [EC:2.3.2.26]"
			},
			{
				"name":"101917966 HECW1; HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1\tK12167 HECW1; E3 ubiquitin-protein ligase HECW1 [EC:2.3.2.26]"
			},
			{
				"name":"101923545 HECW2; HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2\tK12168 HECW2; E3 ubiquitin-protein ligase HECW2 [EC:2.3.2.26]"
			},
			{
				"name":"101922790 HECTD1; HECT domain E3 ubiquitin protein ligase 1\tK12231 HECTD1; E3 ubiquitin-protein ligase HECTD1 [EC:2.3.2.26]"
			},
			{
				"name":"101912810 HECTD2; HECT domain E3 ubiquitin protein ligase 2\tK12232 HECTD2; E3 ubiquitin-protein ligase HECTD2 [EC:2.3.2.26]"
			},
			{
				"name":"101914113 E3 ubiquitin-protein ligase HECTD3-like\tK12233 HECTD3; E3 ubiquitin-protein ligase HECTD3 [EC:2.3.2.26]"
			},
			{
				"name":"101923235 HECTD4; HECT domain E3 ubiquitin protein ligase 4\tK17849 HECTD4; E3 ubiquitin-protein ligase HECTD4 [EC:2.3.2.26]"
			},
			{
				"name":"HECT type E3 associated proteins",
				"children":[
				{
					"name":"101923632 NDFIP1; Nedd4 family interacting protein 1\tK25839 NDFIP; NEDD4 family-interacting protein"
				},
				{
					"name":"101912606 N4BP3; NEDD4 binding protein 3\tK26473 N4BP3; NEDD4-binding protein 3"
				},
				{
					"name":"101923551 chromosome unknown open reading frame, human C16orf72\tK27699 HAPSTR1; HUWE1-associated protein modifying stress responses 1"
				}
				]
			}
			]
		},
		{
			"name":"U-box type E3",
			"children":[
			{
				"name":"101912930 UBE4A; ubiquitination factor E4A\tK10596 UBE4A; ubiquitin conjugation factor E4 A [EC:2.3.2.27]"
			},
			{
				"name":"101920603 UBE4B; ubiquitination factor E4B\tK10597 UBE4B; ubiquitin conjugation factor E4 B [EC:2.3.2.27]"
			},
			{
				"name":"101921639 STUB1; STIP1 homology and U-box containing protein 1\tK09561 STUB1; STIP1 homology and U-box containing protein 1 [EC:2.3.2.27]"
			},
			{
				"name":"101914969 PPIL2; peptidylprolyl isomerase like 2\tK10598 PPIL2; peptidyl-prolyl cis-trans isomerase-like 2 [EC:5.2.1.8]"
			},
			{
				"name":"101915708 PRPF19; pre-mRNA processing factor 19\tK10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]"
			},
			{
				"name":"101920915 RBBP6; RB binding protein 6, ubiquitin ligase\tK10624 RBBP6; E3 ubiquitin-protein ligase RBBP6 [EC:2.3.2.27]"
			},
			{
				"name":"101910968 UBOX5; U-box domain containing 5\tK10600 UBOX5; U-box domain-containing protein 5 [EC:2.3.2.27]"
			}
			]
		},
		{
			"name":"Single Ring-finger type E3",
			"children":[
			{
				"name":"BRE1 proteins",
				"children":[
				{
					"name":"101916362 RNF20; ring finger protein 20\tK10696 BRE1; E3 ubiquitin-protein ligase BRE1 [EC:2.3.2.27]"
				}
				]
			},
			{
				"name":"CBL proteins",
				"children":[
				{
					"name":"101919050 CBL; Cbl proto-oncogene\tK04707 CBL; E3 ubiquitin-protein ligase CBL [EC:2.3.2.27]"
				},
				{
					"name":"101912806 CBLB; Cbl proto-oncogene B\tK22517 CBLB; E3 ubiquitin-protein ligase CBL-B [EC:2.3.2.27]"
				}
				]
			},
			{
				"name":"SINA (Seven in absentia) proteins",
				"children":[
				{
					"name":"101911681 SIAH1; siah E3 ubiquitin protein ligase 1\tK04506 SIAH1; E3 ubiquitin-protein ligase SIAH1 [EC:2.3.2.27]"
				},
				{
					"name":"106112263 SIAH2; siah E3 ubiquitin protein ligase 2\tK08742 SIAH2; E3 ubiquitin-protein ligase SIAH2 [EC:2.3.2.27]"
				}
				]
			},
			{
				"name":"Ligand of Numb proteins",
				"children":[
				{
					"name":"101910578 ligand of Numb protein X 2-like\tK10692 LNX1_2; ligand of Numb protein X 1\/2 [EC:2.3.2.27]"
				},
				{
					"name":"101913706 LNX1; ligand of numb-protein X 1\tK10692 LNX1_2; ligand of Numb protein X 1\/2 [EC:2.3.2.27]"
				},
				{
					"name":"101923348 LNX2; ligand of numb-protein X 2\tK10692 LNX1_2; ligand of Numb protein X 1\/2 [EC:2.3.2.27]"
				},
				{
					"name":"101915347 PDZRN4; PDZ domain containing ring finger 4\tK15682 PDZRN3_4; ligand of Numb protein X 3\/4 [EC:2.3.2.27]"
				},
				{
					"name":"101915495 PDZRN3; PDZ domain containing ring finger 3\tK15682 PDZRN3_4; ligand of Numb protein X 3\/4 [EC:2.3.2.27]"
				}
				]
			},
			{
				"name":"March proteins",
				"children":[
				{
					"name":"101910952 MARCH8; membrane associated ring-CH-type finger 8\tK10656 MARCH1_8; E3 ubiquitin-protein ligase MARCH1\/8 [EC:2.3.2.27]"
				},
				{
					"name":"101914553 MARCH1; membrane associated ring-CH-type finger 1\tK10656 MARCH1_8; E3 ubiquitin-protein ligase MARCH1\/8 [EC:2.3.2.27]"
				},
				{
					"name":"101921808 MARCH3; membrane associated ring-CH-type finger 3\tK10657 MARCH2_3; E3 ubiquitin-protein ligase MARCH2\/3 [EC:2.3.2.27]"
				},
				{
					"name":"101922945 MARCH2; membrane associated ring-CH-type finger 2\tK10657 MARCH2_3; E3 ubiquitin-protein ligase MARCH2\/3 [EC:2.3.2.27]"
				},
				{
					"name":"101918971 MARCH11; membrane associated ring-CH-type finger 11\tK10659 MARCH4_9_11; E3 ubiquitin-protein ligase MARCH4\/9\/11 [EC:2.3.2.27]"
				},
				{
					"name":"101923007 MARCH4; membrane associated ring-CH-type finger 4\tK10659 MARCH4_9_11; E3 ubiquitin-protein ligase MARCH4\/9\/11 [EC:2.3.2.27]"
				},
				{
					"name":"101914882 MARCH5; membrane associated ring-CH-type finger 5\tK10660 MARCH5; E3 ubiquitin-protein ligase MARCH5 [EC:2.3.2.27]"
				},
				{
					"name":"101913388 MARCH6; membrane associated ring-CH-type finger 6\tK10661 MARCH6; E3 ubiquitin-protein ligase MARCH6 [EC:2.3.2.27]"
				},
				{
					"name":"101920545 MARCH7; membrane associated ring-CH-type finger 7\tK10662 MARCH7; E3 ubiquitin-protein ligase MARCH7 [EC:2.3.2.27]"
				}
				]
			},
			{
				"name":"MDM2\/MDM4 proteins",
				"children":[
				{
					"name":"101924125 MDM2; MDM2 proto-oncogene\tK06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]"
				},
				{
					"name":"101915267 MDM4; MDM4, p53 regulator\tK10127 MDM4; protein Mdm4"
				}
				]
			},
			{
				"name":"NFX1 proteins",
				"children":[
				{
					"name":"101913901 NFX1; nuclear transcription factor, X-box binding 1\tK12236 NFX1; transcriptional repressor NF-X1"
				},
				{
					"name":"101922819 NFXL1; nuclear transcription factor, X-box binding like 1\tK15683 NFXL1; NF-X1-type zinc finger protein NFXL1"
				}
				]
			},
			{
				"name":"Pellino proteins",
				"children":[
				{
					"name":"101912960 PELI1; pellino E3 ubiquitin protein ligase 1\tK11964 PELI; pellino [EC:2.3.2.27]"
				},
				{
					"name":"101915533 PELI2; pellino E3 ubiquitin protein ligase family member 2\tK11964 PELI; pellino [EC:2.3.2.27]"
				}
				]
			},
			{
				"name":"Peripheral membrane proteins",
				"children":[
				{
					"name":"101920541 PEX10; peroxisomal biogenesis factor 10\tK13346 PEX10; peroxin-10 [EC:2.3.2.27]"
				},
				{
					"name":"101922315 PEX12; peroxisomal biogenesis factor 12\tK13345 PEX12; peroxin-12"
				},
				{
					"name":"101911955 PEX2; peroxisomal biogenesis factor 2\tK06664 PEX2; peroxin-2 [EC:2.3.2.27 2.3.2.36]"
				}
				]
			},
			{
				"name":"RBR proteins",
				"children":[
				{
					"name":"101918371 PARK2; parkin RBR E3 ubiquitin protein ligase\tK04556 PARK2; parkin [EC:2.3.2.31]"
				},
				{
					"name":"101920797 ANKIB1; ankyrin repeat and IBR domain containing 1\tK11967 ANKIB1; ankyrin repeat and IBR domain-containing protein 1 [EC:2.3.2.31]"
				},
				{
					"name":"101921271 ARIH1; ariadne RBR E3 ubiquitin protein ligase 1\tK11968 ARIH1; ariadne-1 [EC:2.3.2.31]"
				},
				{
					"name":"101911249 ARIH2; ariadne RBR E3 ubiquitin protein ligase 2\tK11969 ARIH2; ariadne-2 [EC:2.3.2.31]"
				},
				{
					"name":"101917453 SHARPIN; SHANK associated RH domain interactor\tK10630 RBCK1; RanBP-type and C3HC4-type zinc finger-containing protein 1 [EC:2.3.2.31]"
				},
				{
					"name":"101915291 RNF14; ring finger protein 14\tK11971 RNF14; E3 ubiquitin-protein ligase RNF14 [EC:2.3.2.31]"
				},
				{
					"name":"101911083 RNF19A; ring finger protein 19A, RBR E3 ubiquitin protein ligase\tK11972 RNF19A; E3 ubiquitin-protein ligase RNF19A [EC:2.3.2.31]"
				},
				{
					"name":"101913654 E3 ubiquitin-protein ligase RNF19A-like\tK11973 RNF19B; E3 ubiquitin-protein ligase RNF19B [EC:2.3.2.31]"
				},
				{
					"name":"101923190 RNF19B; ring finger protein 19B\tK11973 RNF19B; E3 ubiquitin-protein ligase RNF19B [EC:2.3.2.31]"
				},
				{
					"name":"101912567 RNF34; ring finger protein 34\tK20804 RNF34; E3 ubiquitin-protein ligase RNF34 [EC:2.3.2.31]"
				},
				{
					"name":"101921349 RFFL; ring finger and FYVE like domain containing E3 ubiquitin protein ligase\tK20804 RNF34; E3 ubiquitin-protein ligase RNF34 [EC:2.3.2.31]"
				},
				{
					"name":"101914399 RNF144A; ring finger protein 144A\tK11975 RNF144; E3 ubiquitin-protein ligase RNF144 [EC:2.3.2.31]"
				},
				{
					"name":"101917576 RNF144B; ring finger protein 144B\tK11975 RNF144; E3 ubiquitin-protein ligase RNF144 [EC:2.3.2.31]"
				},
				{
					"name":"101914357 RNF168; ring finger protein 168\tK20779 RNF168; E3 ubiquitin-protein ligase RNF168 [EC:2.3.2.31]"
				},
				{
					"name":"101920802 RNF169; ring finger protein 169\tK20805 RNF169; E3 ubiquitin-protein ligase RNF169 [EC:2.3.2.31]"
				},
				{
					"name":"101912893 RNF216; ring finger protein 216\tK11976 RNF216; E3 ubiquitin-protein ligase RNF216 [EC:2.3.2.31]"
				},
				{
					"name":"101918736 RNF217; ring finger protein 217\tK11977 RNF217; E3 ubiquitin-protein ligase RNF217 [EC:2.3.2.31]"
				}
				]
			},
			{
				"name":"TRAF proteins",
				"children":[
				{
					"name":"101911961 TRAF2; TNF receptor associated factor 2\tK03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]"
				},
				{
					"name":"101921400 TRAF5; TNF receptor associated factor 5\tK09849 TRAF5; TNF receptor-associated factor 5"
				},
				{
					"name":"101912003 TRAF6; TNF receptor associated factor 6\tK03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]"
				},
				{
					"name":"101920032 TRAF7; TNF receptor associated factor 7\tK10646 TRAF7; E3 ubiquitin-protein ligase TRAF7 [EC:2.3.2.27]"
				}
				]
			},
			{
				"name":"TRIM\/RBCC proteins",
				"children":[
				{
					"name":"101924731 MID2; midline 2\tK10647 TRIM1; midline 2 [EC:2.3.2.27]"
				},
				{
					"name":"101919922 TRIM3; tripartite motif containing 3\tK11997 TRIM2_3; tripartite motif-containing protein 2\/3"
				},
				{
					"name":"101924211 TRIM2; tripartite motif containing 2\tK11997 TRIM2_3; tripartite motif-containing protein 2\/3"
				},
				{
					"name":"101916396 tripartite motif-containing protein 7-like\tK12000 TRIM7; tripartite motif-containing protein 7"
				},
				{
					"name":"101920985 tripartite motif-containing protein 7-like\tK12000 TRIM7; tripartite motif-containing protein 7"
				},
				{
					"name":"101921500 TRIM7; tripartite motif containing 7\tK12000 TRIM7; tripartite motif-containing protein 7"
				},
				{
					"name":"101924625 TRIM8; tripartite motif containing 8\tK12001 TRIM8; tripartite motif-containing protein 8 [EC:2.3.2.27]"
				},
				{
					"name":"101912940 TRIM9; tripartite motif containing 9\tK10649 TRIM9_67; tripartite motif-containing protein 9\/67"
				},
				{
					"name":"101920829 TRIM67; tripartite motif containing 67\tK10649 TRIM9_67; tripartite motif-containing protein 9\/67"
				},
				{
					"name":"101911707 TRIM13; tripartite motif containing 13\tK12003 TRIM13; tripartite motif-containing protein 13 [EC:2.3.2.27]"
				},
				{
					"name":"101910797 TRIM14; tripartite motif containing 14\tK12004 TRIM14; tripartite motif-containing protein 14"
				},
				{
					"name":"101922750 MID1; midline 1\tK08285 TRIM18; midline 1 [EC:2.3.2.27]"
				},
				{
					"name":"101910305 TRIM23; tripartite motif containing 23\tK07963 TRIM23; tripartite motif-containing protein 23 [EC:2.3.2.27]"
				},
				{
					"name":"101910466 TRIM24; tripartite motif containing 24\tK08881 TRIM24; tripartite motif-containing protein 24 [EC:2.3.2.27]"
				},
				{
					"name":"101923333 TRIM25; tripartite motif containing 25\tK10652 TRIM25; tripartite motif-containing protein 25 [EC:2.3.2.27]"
				},
				{
					"name":"101924827 TRIM28; tripartite motif containing 28\tK08882 TRIM28; tripartite motif-containing protein 28 [EC:2.3.2.27]"
				},
				{
					"name":"101917659 TRIM29; tripartite motif containing 29\tK12010 TRIM29; tripartite motif-containing protein 29"
				},
				{
					"name":"101917378 TRIM32; tripartite motif containing 32\tK10607 TRIM32; tripartite motif-containing protein 32 [EC:2.3.2.27]"
				},
				{
					"name":"101915251 TRIM33; tripartite motif containing 33\tK08883 TRIM33; tripartite motif-containing protein 33 [EC:2.3.2.27]"
				},
				{
					"name":"101922077 TRIM35; tripartite motif containing 35\tK12012 TRIM35; tripartite motif-containing protein 35"
				},
				{
					"name":"101916893 TRIM36; tripartite motif containing 36\tK12013 TRIM36; tripartite motif-containing protein 36 [EC:2.3.2.27]"
				},
				{
					"name":"101924329 TRIM37; tripartite motif containing 37\tK10608 TRIM37; tripartite motif-containing protein 37 [EC:2.3.2.27]"
				},
				{
					"name":"101914867 E3 ubiquitin-protein ligase TRIM39-like\tK12015 TRIM39; tripartite motif-containing protein 39 \/ bloodthirsty-related gene family protein [EC:2.3.2.27]"
				},
				{
					"name":"101921152 E3 ubiquitin-protein ligase TRIM39-like\tK12015 TRIM39; tripartite motif-containing protein 39 \/ bloodthirsty-related gene family protein [EC:2.3.2.27]"
				},
				{
					"name":"101924261 E3 ubiquitin-protein ligase TRIM39-like\tK12015 TRIM39; tripartite motif-containing protein 39 \/ bloodthirsty-related gene family protein [EC:2.3.2.27]"
				},
				{
					"name":"101910859 TRIM41; E3 ubiquitin-protein ligase TRIM41\tK12017 TRIM41; tripartite motif-containing protein 41 [EC:2.3.2.27]"
				},
				{
					"name":"101915613 TRIM42; tripartite motif containing 42\tK12018 TRIM42; tripartite motif-containing protein 42"
				},
				{
					"name":"101916846 TRIM45; tripartite motif containing 45\tK12021 TRIM45; tripartite motif-containing protein 45"
				},
				{
					"name":"101920823 TRIM46; tripartite motif containing 46\tK12022 TRIM46; tripartite motif-containing protein 46"
				},
				{
					"name":"101922389 TRIM47; tripartite motif containing 47\tK12023 TRIM47; tripartite motif-containing protein 47"
				},
				{
					"name":"101915566 TRIM50; tripartite motif containing 50\tK12024 TRIM50_73_74; tripartite motif-containing protein 50\/73\/74"
				},
				{
					"name":"101915487 TRIM54; tripartite motif containing 54\tK10653 TRIM54; tripartite motif-containing protein 54"
				},
				{
					"name":"101914125 TRIM55; tripartite motif containing 55\tK10654 TRIM55; tripartite motif-containing protein 55"
				},
				{
					"name":"101912009 TRIM59; tripartite motif containing 59\tK12028 TRIM59; tripartite motif-containing protein 59"
				},
				{
					"name":"101918108 TRIM62; E3 ubiquitin-protein ligase TRIM62\tK12030 TRIM62; tripartite motif-containing protein 62 [EC:2.3.2.27]"
				},
				{
					"name":"101922009 TRIM63; E3 ubiquitin-protein ligase TRIM63\tK10655 TRIM63; tripartite motif-containing protein 63 [EC:2.3.2.27]"
				},
				{
					"name":"101917499 TRIM66; tripartite motif containing 66\tK12032 TRIM66; tripartite motif-containing protein 66"
				},
				{
					"name":"101913689 TRIM71; tripartite motif containing 71\tK12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]"
				}
				]
			},
			{
				"name":"UBR box proteins",
				"children":[
				{
					"name":"101923198 UBR1; ubiquitin protein ligase E3 component n-recognin 1\tK10625 UBR1; E3 ubiquitin-protein ligase UBR1 [EC:2.3.2.27]"
				},
				{
					"name":"101919950 UBR2; ubiquitin protein ligase E3 component n-recognin 2\tK10626 UBR2; E3 ubiquitin-protein ligase UBR2 [EC:2.3.2.27]"
				},
				{
					"name":"101922658 UBR3; ubiquitin protein ligase E3 component n-recognin 3 (putative)\tK11978 UBR3; E3 ubiquitin-protein ligase UBR3 [EC:2.3.2.27]"
				},
				{
					"name":"101917265 UBR4; ubiquitin protein ligase E3 component n-recognin 4\tK10691 UBR4; E3 ubiquitin-protein ligase UBR4 [EC:2.3.2.27]"
				},
				{
					"name":"101920314 UBR7; ubiquitin protein ligase E3 component n-recognin 7 (putative)\tK11979 UBR7; E3 ubiquitin-protein ligase UBR7 [EC:2.3.2.27]"
				}
				]
			},
			{
				"name":"ATL proteins"
			},
			{
				"name":"Other single Ring-finger type E3",
				"children":[
				{
					"name":"101910285 AMFR; autocrine motility factor receptor\tK10636 AMFR; E3 ubiquitin-protein ligase AMFR [EC:2.3.2.36]"
				},
				{
					"name":"101917765 AIRE; autoimmune regulator\tK10603 AIRE; autoimmune regulator"
				},
				{
					"name":"101913571 BFAR; bifunctional apoptosis regulator\tK15684 BFAR; bifunctional apoptosis regulator"
				},
				{
					"name":"101924079 BIRC2; baculoviral IAP repeat containing 2\tK16060 BIRC2_3; baculoviral IAP repeat-containing protein 2\/3"
				},
				{
					"name":"101916449 XIAP; X-linked inhibitor of apoptosis\tK04725 XIAP; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]"
				},
				{
					"name":"101916314 BIRC7; baculoviral IAP repeat containing 7\tK16061 BIRC7_8; baculoviral IAP repeat-containing protein 7\/8"
				},
				{
					"name":"101924276 BRAP; BRCA1 associated protein\tK10632 BRAP; BRCA1-associated protein [EC:2.3.2.27]"
				},
				{
					"name":"106112589 BRCA1; BRCA1, DNA repair associated\tK10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]"
				},
				{
					"name":"101924639 CBLL1; Cbl proto-oncogene like 1\tK15685 CBLL1; E3 ubiquitin-protein ligase Hakai [EC:2.3.2.27]"
				},
				{
					"name":"101917908 CHFR; checkpoint with forkhead and ring finger domains\tK10644 CHFR; E3 ubiquitin-protein ligase CHFR [EC:2.3.2.27]"
				},
				{
					"name":"101921513 CNOT4; CCR4-NOT transcription complex subunit 4\tK10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]"
				},
				{
					"name":"101919944 DCST1; DC-STAMP domain containing 1\tK22375 DCST1; E3 ubiquitin-protein ligase DCST1 [EC:2.3.2.27]"
				},
				{
					"name":"101915058 DTX4; deltex E3 ubiquitin ligase 4\tK06058 DTX; deltex [EC:2.3.2.27]"
				},
				{
					"name":"101916575 DTX1; deltex E3 ubiquitin ligase 1\tK06058 DTX; deltex [EC:2.3.2.27]"
				},
				{
					"name":"101922903 DTX2; deltex E3 ubiquitin ligase 2\tK06058 DTX; deltex [EC:2.3.2.27]"
				},
				{
					"name":"101923909 DTX3L; deltex E3 ubiquitin ligase 3L\tK06058 DTX; deltex [EC:2.3.2.27]"
				},
				{
					"name":"101920999 FANCL; Fanconi anemia complementation group L\tK10606 FANCL; E3 ubiquitin-protein ligase FANCL [EC:2.3.2.27]"
				},
				{
					"name":"101912904 KCMF1; potassium channel modulatory factor 1\tK22376 KCMF1; E3 ubiquitin-protein ligase KCMF1 [EC:2.3.2.27]"
				},
				{
					"name":"101920513 LRSAM1; leucine rich repeat and sterile alpha motif containing 1\tK10641 LRSAM1; E3 ubiquitin-protein ligase LRSAM1 [EC:2.3.2.27]"
				},
				{
					"name":"101916996 LTN1; listerin E3 ubiquitin protein ligase 1\tK22377 LTN1; E3 ubiquitin-protein ligase listerin [EC:2.3.2.27]"
				},
				{
					"name":"101911178 MAP3K1; mitogen-activated protein kinase kinase kinase 1\tK04416 MAP3K1; mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25]"
				},
				{
					"name":"101912341 MEX3D; mex-3 RNA binding family member D\tK15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]"
				},
				{
					"name":"101917421 MEX3B; mex-3 RNA binding family member B\tK15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]"
				},
				{
					"name":"101922045 MEX3C; mex-3 RNA binding family member C\tK15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]"
				},
				{
					"name":"101923230 MEX3A; mex-3 RNA binding family member A\tK15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]"
				},
				{
					"name":"101922747 MGRN1; mahogunin ring finger 1\tK10604 MGRN1; E3 ubiquitin-protein ligase MGRN1 [EC:2.3.2.27]"
				},
				{
					"name":"101910873 MIB2; mindbomb E3 ubiquitin protein ligase 2\tK10645 MIB; E3 ubiquitin-protein ligase mind-bomb [EC:2.3.2.27]"
				},
				{
					"name":"101916554 MIB1; mindbomb E3 ubiquitin protein ligase 1\tK10645 MIB; E3 ubiquitin-protein ligase mind-bomb [EC:2.3.2.27]"
				},
				{
					"name":"101913727 MKRN2; makorin ring finger protein 2\tK15687 MKRN; E3 ubiquitin-protein ligase makorin [EC:2.3.2.27]"
				},
				{
					"name":"101920294 MKRN1; makorin ring finger protein 1\tK15687 MKRN; E3 ubiquitin-protein ligase makorin [EC:2.3.2.27]"
				},
				{
					"name":"101912500 mitochondrial ubiquitin ligase activator of nfkb 1-A-like\tK15688 MUL1; E3 ubiquitin-protein ligase MUL1 [EC:2.3.2.27]"
				},
				{
					"name":"101915544 MUL1; mitochondrial E3 ubiquitin protein ligase 1\tK15688 MUL1; E3 ubiquitin-protein ligase MUL1 [EC:2.3.2.27]"
				},
				{
					"name":"101918329 MYCBP2; MYC binding protein 2, E3 ubiquitin protein ligase\tK10693 MYCBP2; RCR-type E3 ubiquitin transferase [EC:2.3.2.33]"
				},
				{
					"name":"101910641 MYLIP; myosin regulatory light chain interacting protein\tK10637 MYLIP; E3 ubiquitin-protein ligase MYLIP [EC:2.3.2.27]"
				},
				{
					"name":"101917900 NEURL1B; neuralized E3 ubiquitin protein ligase 1B\tK01931 NEUR; protein neuralized [EC:2.3.2.27]"
				},
				{
					"name":"101918917 NEURL1; neuralized E3 ubiquitin protein ligase 1\tK01931 NEUR; protein neuralized [EC:2.3.2.27]"
				},
				{
					"name":"101919074 NHLRC1; NHL repeat containing E3 ubiquitin protein ligase 1\tK10602 NHLRC1; E3 ubiquitin-protein ligase NHLRC1 [EC:2.3.2.27]"
				},
				{
					"name":"101917974 RNF219; ring finger protein 219\tK24091 OBI1; ORC ubiquitin ligase 1 [EC:2.3.2.27]"
				},
				{
					"name":"101921579 RAD18; RAD18, E3 ubiquitin protein ligase\tK10627 RAD18; E3 ubiquitin-protein ligase RAD18 [EC:2.3.2.27]"
				},
				{
					"name":"101912181 RAG1; recombination activating 1\tK10628 RAG1; V(D)J recombination-activating protein 1 [EC:2.3.2.27]"
				},
				{
					"name":"101921704 RCHY1; ring finger and CHY zinc finger domain containing 1\tK10144 RCHY1; RING finger and CHY zinc finger domain-containing protein 1 [EC:2.3.2.27]"
				},
				{
					"name":"101914911 RC3H1; ring finger and CCCH-type domains 1\tK15690 RC3H; RING finger and CCCH-type zinc finger domain-containing protein"
				},
				{
					"name":"101917550 RC3H2; ring finger and CCCH-type domains 2\tK15690 RC3H; RING finger and CCCH-type zinc finger domain-containing protein"
				},
				{
					"name":"101924035 RFWD2; ring finger and WD repeat domain 2\tK10143 RFWD2; E3 ubiquitin-protein ligase RFWD2 [EC:2.3.2.27]"
				},
				{
					"name":"101919409 RFWD3; ring finger and WD repeat domain 3\tK15691 RFWD3; E3 ubiquitin-protein ligase RFWD3 [EC:2.3.2.27]"
				},
				{
					"name":"101921833 RNF2; ring finger protein 2\tK10695 RNF1_2; E3 ubiquitin-protein ligase RNF1\/2 [EC:2.3.2.27]"
				},
				{
					"name":"101914370 E3 ubiquitin-protein ligase RNF4-like\tK22651 RNF4; E3 ubiquitin-protein ligase RNF4 [EC:2.3.2.27]"
				},
				{
					"name":"101920214 RNF4; ring finger protein 4\tK22651 RNF4; E3 ubiquitin-protein ligase RNF4 [EC:2.3.2.27]"
				},
				{
					"name":"101921497 RNF185; ring finger protein 185\tK10666 RNF5_185; E3 ubiquitin-protein ligase RNF5\/185 [EC:2.3.2.27]"
				},
				{
					"name":"101924213 RNF6; ring finger protein 6\tK22753 RNF6; E3 ubiquitin-protein ligase RNF6 [EC:2.3.2.27]"
				},
				{
					"name":"101914230 RNF8; ring finger protein 8\tK10667 RNF8; E3 ubiquitin-protein ligase RNF8 [EC:2.3.2.27]"
				},
				{
					"name":"101913078 RNF10; ring finger protein 10\tK26979 RNF10; E3 ubiquitin-protein ligase RNF10 [EC:2.3.2.27]"
				},
				{
					"name":"101918082 RNF11; ring finger protein 11\tK11980 RNF11; E3 ubiquitin-protein ligase RNF11"
				},
				{
					"name":"101925000 RLIM; ring finger protein, LIM domain interacting\tK16271 RLIM; E3 ubiquitin-protein ligase RLIM [EC:2.3.2.27]"
				},
				{
					"name":"101923457 RNF13; ring finger protein 13\tK15692 RNF13; E3 ubiquitin-protein ligase RNF13 [EC:2.3.2.27]"
				},
				{
					"name":"101912033 RNF25; ring finger protein 25\tK10640 RNF25; E3 ubiquitin-protein ligase RNF25 [EC:2.3.2.27]"
				},
				{
					"name":"101919391 RNF26; ring finger protein 26\tK15693 RNF26; E3 ubiquitin-protein ligase RNF26 [EC:2.3.2.27]"
				},
				{
					"name":"101910974 RNF44; ring finger protein 44\tK19041 RNF38_44; E3 ubiquitin-protein ligase RNF38\/44 [EC:2.3.2.27]"
				},
				{
					"name":"101921893 RNF38; ring finger protein 38\tK19041 RNF38_44; E3 ubiquitin-protein ligase RNF38\/44 [EC:2.3.2.27]"
				},
				{
					"name":"101924943 RNF41; ring finger protein 41\tK11981 RNF41; E3 ubiquitin-protein ligase NRDP1 [EC:2.3.2.27]"
				},
				{
					"name":"101911391 RNF43; ring finger protein 43\tK15694 RNF43; E3 ubiquitin-protein ligase RNF43 [EC:2.3.2.27]"
				},
				{
					"name":"101922635 CHMP3; E3 ubiquitin-protein ligase RNF103\tK15695 RNF103; E3 ubiquitin-protein ligase RNF103 [EC:2.3.2.27]"
				},
				{
					"name":"101911037 RNF111; ring finger protein 111\tK10635 RNF111; E3 ubiquitin-protein ligase Arkadia [EC:2.3.2.27]"
				},
				{
					"name":"101917457 RNF114; ring finger protein 114\tK15697 RNF114; E3 ubiquitin-protein ligase RNF114 [EC:2.3.2.27]"
				},
				{
					"name":"101919167 RNF115; ring finger protein 115\tK11982 RNF115_126; E3 ubiquitin-protein ligase RNF115\/126 [EC:2.3.2.27]"
				},
				{
					"name":"101920312 RNF126; ring finger protein 126\tK11982 RNF115_126; E3 ubiquitin-protein ligase RNF115\/126 [EC:2.3.2.27]"
				},
				{
					"name":"101916237 RNF175; ring finger protein 175\tK15698 RNF121_175; RING finger protein 121\/175"
				},
				{
					"name":"101917321 RNF121; ring finger protein 121\tK15698 RNF121_175; RING finger protein 121\/175"
				},
				{
					"name":"101912550 RNF122; ring finger protein 122\tK15699 RNF122; RING finger protein 122"
				},
				{
					"name":"101916231 RNF123; ring finger protein 123\tK12169 KPC1; Kip1 ubiquitination-promoting complex protein 1 [EC:2.3.2.27]"
				},
				{
					"name":"101910947 RNF128; ring finger protein 128, E3 ubiquitin protein ligase\tK10629 RNF128; E3 ubiquitin-protein ligase RNF128 [EC:2.3.2.27]"
				},
				{
					"name":"101917901 RNF130; ring finger protein 130\tK15701 RNF130; E3 ubiquitin-protein ligase RNF130 [EC:2.3.2.27]"
				},
				{
					"name":"101915201 RNF138; ring finger protein 138\tK10668 RNF138; E3 ubiquitin-protein ligase RNF138 [EC:2.3.2.27]"
				},
				{
					"name":"101922909 RNF139; ring finger protein 139\tK15703 RNF139; E3 ubiquitin-protein ligase RNF139 [EC:2.3.2.27]"
				},
				{
					"name":"101923302 RING finger protein 145-like\tK23789 RNF145; E3 ubiquitin-protein ligase RNF145 [EC:2.3.2.27]"
				},
				{
					"name":"101924383 RNF145; ring finger protein 145\tK23789 RNF145; E3 ubiquitin-protein ligase RNF145 [EC:2.3.2.27]"
				},
				{
					"name":"101918213 RNF146; ring finger protein 146\tK15700 RNF146; E3 ubiquitin-protein ligase RNF146 [EC:2.3.2.27]"
				},
				{
					"name":"101912713 RNF149; ring finger protein 149\tK15704 RNF149; E3 ubiquitin-protein ligase RNF149 [EC:2.3.2.27]"
				},
				{
					"name":"101914776 RNF152; ring finger protein 152\tK15705 RNF152; E3 ubiquitin-protein ligase RNF152 [EC:2.3.2.27]"
				},
				{
					"name":"101911185 RNF157; ring finger protein 157\tK25192 RNF157; E3 ubiquitin-protein ligase RNF157 [EC:2.3.2.27]"
				},
				{
					"name":"101920044 RNF165; ring finger protein 165\tK17821 RNF165; E3 ubiquitin-protein ligase RNF165 [EC:2.3.2.27]"
				},
				{
					"name":"101915325 RNF166; ring finger protein 166\tK17044 RNF166; E3 ubiquitin-protein ligase RNF166 [EC:2.3.2.27]"
				},
				{
					"name":"101923867 RNF170; ring finger protein 170\tK15707 RNF170; E3 ubiquitin-protein ligase RNF170 [EC:2.3.2.27]"
				},
				{
					"name":"106112743 E3 ubiquitin-protein ligase RNF170-like\tK15707 RNF170; E3 ubiquitin-protein ligase RNF170 [EC:2.3.2.27]"
				},
				{
					"name":"106112696 RNF180; ring finger protein 180\tK15708 RNF180; E3 ubiquitin-protein ligase RNF180 [EC:2.3.2.27]"
				},
				{
					"name":"101912635 E3 ubiquitin-protein ligase RNF182-like\tK11983 RNF182; E3 ubiquitin-protein ligase RNF182 [EC:2.3.2.27]"
				},
				{
					"name":"101915444 RNF182; ring finger protein 182\tK11983 RNF182; E3 ubiquitin-protein ligase RNF182 [EC:2.3.2.27]"
				},
				{
					"name":"101916397 RNF186; ring finger protein 186\tK25214 RNF186; E3 ubiquitin-protein ligase RNF186 [EC:2.3.2.27]"
				},
				{
					"name":"101915846 uncharacterized LOC101915846\tK22754 RNF213; E3 ubiquitin-protein ligase RNF213 [EC:2.3.2.27]"
				},
				{
					"name":"101919165 RNF213; ring finger protein 213\tK22754 RNF213; E3 ubiquitin-protein ligase RNF213 [EC:2.3.2.27]"
				},
				{
					"name":"106112616 uncharacterized LOC106112616\tK22754 RNF213; E3 ubiquitin-protein ligase RNF213 [EC:2.3.2.27]"
				},
				{
					"name":"101915577 RNF220; ring finger protein 220\tK25174 RNF220; E3 ubiquitin-protein ligase RNF220 [EC:2.3.2.27]"
				},
				{
					"name":"101911034 RNFT1; ring finger protein, transmembrane 1\tK22379 RNFT1; E3 ubiquitin-protein ligase RNFT1 [EC:2.3.2.27]"
				},
				{
					"name":"101917213 RNFT2; ring finger protein, transmembrane 2\tK28516 RNFT2; E3 ubiquitin-protein ligase RNFT2"
				},
				{
					"name":"101920921 SHPRH; SNF2 histone linker PHD RING helicase\tK15710 SHPRH; E3 ubiquitin-protein ligase SHPRH [EC:5.6.2.- 2.3.2.27]"
				},
				{
					"name":"101915518 SH3RF1; SH3 domain containing ring finger 1\tK12171 SH3RF; E3 ubiquitin-protein ligase SH3RF [EC:2.3.2.27]"
				},
				{
					"name":"101921617 SH3RF2; SH3 domain containing ring finger 2\tK12171 SH3RF; E3 ubiquitin-protein ligase SH3RF [EC:2.3.2.27]"
				},
				{
					"name":"101924863 SH3RF3; SH3 domain containing ring finger 3\tK12171 SH3RF; E3 ubiquitin-protein ligase SH3RF [EC:2.3.2.27]"
				},
				{
					"name":"101911321 HLTF; helicase like transcription factor\tK15711 SMARCA3; SWI\/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A3 [EC:5.6.2. 2.3.2.27]"
				},
				{
					"name":"101918658 SYVN1; synoviolin 1\tK10601 SYVN1; E3 ubiquitin-protein ligase synoviolin [EC:2.3.2.27]"
				},
				{
					"name":"101916398 TMEM129; transmembrane protein 129\tK22380 TMEM129; E3 ubiquitin-protein ligase TM129 [EC:2.3.2.27]"
				},
				{
					"name":"101919954 TOPORS; TOP1 binding arginine\/serine rich protein\tK10631 TOPORS; E3 ubiquitin-protein ligase Topors [EC:2.3.2.27]"
				},
				{
					"name":"101919979 TRAIP; TRAF interacting protein\tK11985 TRAIP; TRAF-interacting protein [EC:2.3.2.27]"
				},
				{
					"name":"101921367 TTC3; tetratricopeptide repeat domain 3\tK15712 TTC3; E3 ubiquitin-protein ligase TTC3 [EC:2.3.2.27]"
				},
				{
					"name":"101912822 UHRF1; ubiquitin like with PHD and ring finger domains 1\tK10638 UHRF1; E3 ubiquitin-protein ligase UHRF1 [EC:2.3.2.27]"
				},
				{
					"name":"101922266 UHRF2; ubiquitin like with PHD and ring finger domains 2\tK15713 UHRF2; E3 ubiquitin-protein ligase UHRF2 [EC:2.3.2.27]"
				},
				{
					"name":"101923304 UNKL; unkempt family like zinc finger\tK23047 UNKL; E3 ubiquitin-protein ligase UNKL [EC:2.3.2.27]"
				},
				{
					"name":"101924705 ZNF598; zinc finger protein 598\tK22381 ZNF598; E3 ubiquitin-protein ligase ZNF598 [EC:2.3.2.27]"
				},
				{
					"name":"101915409 ZFP91; ZFP91 zinc finger protein\tK25175 ZFP91; E3 ubiquitin-protein ligase ZFP91 [EC:2.3.2.27]"
				},
				{
					"name":"101917505 ZNRF1; zinc and ring finger 1\tK10694 ZNRF1_2; E3 ubiquitin-protein ligase ZNRF1\/2 [EC:2.3.2.27]"
				},
				{
					"name":"101916843 ZNRF3; zinc and ring finger 3\tK16273 ZNRF3; E3 ubiquitin-protein ligase ZNRF3 [EC:2.3.2.27]"
				}
				]
			}
			]
		},
		{
			"name":"Atypical E3",
			"children":[
			{
				"name":"101911539 JADE2; jade family PHD finger 2\tK22155 JADE2; E3 ubiquitin-protein ligase Jade-2 [EC:2.3.2.27]"
			},
			{
				"name":"101911134 E4F1; E4F transcription factor 1\tK22401 E4F1; transcription factor E4F1 \/ E3 ubiquitin-protein ligase [EC:2.3.2.27]"
			},
			{
				"name":"101913578 NSMCE1; NSE1 homolog, SMC5-SMC6 complex component\tK22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27]"
			},
			{
				"name":"106112871 IRF2BPL; interferon regulatory factor 2 binding protein like\tK22383 IRF2BP; interferon regulatory factor 2-binding protein"
			}
			]
		},
		{
			"name":"UBL E3 ligases",
			"children":[
			{
				"name":"101916874 RBX1; ring-box 1\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
			},
			{
				"name":"101919954 TOPORS; TOP1 binding arginine\/serine rich protein\tK10631 TOPORS; E3 ubiquitin-protein ligase Topors [EC:2.3.2.27]"
			},
			{
				"name":"101910441 RANBP2; E3 SUMO-protein ligase RanBP2\tK12172 RANBP2; E3 SUMO-protein ligase RanBP2 [EC:2.3.2.-]"
			},
			{
				"name":"101924264 PIAS1; protein inhibitor of activated STAT 1\tK04706 PIAS1; E3 SUMO-protein ligase PIAS1 [EC:2.3.2.-]"
			},
			{
				"name":"101918024 PIAS2; protein inhibitor of activated STAT 2\tK16063 PIAS2; E3 SUMO-protein ligase PIAS2 [EC:2.3.2.-]"
			},
			{
				"name":"101911544 PIAS3; protein inhibitor of activated STAT 3\tK16064 PIAS3; E3 SUMO-protein ligase PIAS3 [EC:2.3.2.-]"
			},
			{
				"name":"101919048 PIAS4; protein inhibitor of activated STAT 4\tK16065 PIAS4; E3 SUMO-protein ligase PIAS4 [EC:2.3.2.27]"
			},
			{
				"name":"101910511 PML; uncharacterized LOC101910511\tK10054 PML; E3 SUMO-protein ligase PML [EC:2.3.2.-]"
			},
			{
				"name":"101910853 E3 ubiquitin-protein ligase TRIM71-like\tK10054 PML; E3 SUMO-protein ligase PML [EC:2.3.2.-]"
			},
			{
				"name":"101918311 CBX4; chromobox 4\tK11452 CBX4; E3 SUMO-protein ligase CBX4 [EC:2.3.2.-]"
			},
			{
				"name":"101920619 NSMCE2; NSE2\/MMS21 homolog, SMC5-SMC6 complex SUMO ligase\tK22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]"
			},
			{
				"name":"106112734 E3 SUMO-protein ligase NSE2-like\tK22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]"
			},
			{
				"name":"101917663 RNF212; ring finger protein 212\tK25662 RNF212; E3 SUMO-protein ligase RNF212 [EC:2.3.2.-]"
			},
			{
				"name":"101922111 ZBED1; zinc finger BED-type containing 1\tK24637 ZBED1; zinc finger BED domain-containing protein 1 (E3 SUMO-protein ligase ZBED1) [EC:2.3.2.-]"
			},
			{
				"name":"106112957 zinc finger BED domain-containing protein 1-like\tK24637 ZBED1; zinc finger BED domain-containing protein 1 (E3 SUMO-protein ligase ZBED1) [EC:2.3.2.-]"
			},
			{
				"name":"101923184 ZNF451; zinc finger protein 451\tK25176 ZNF451; E3 SUMO-protein ligase ZNF451 [EC:2.3.2.-]"
			},
			{
				"name":"101923704 UFL1; UFM1 specific ligase 1\tK22755 UFL1; E3 UFM1-protein ligase 1 [EC:2.3.2.-]"
			},
			{
				"name":"101912075 DCUN1D2; defective in cullin neddylation 1 domain containing 2\tK17822 DCUN1D1_2; DCN1-like protein 1\/2"
			},
			{
				"name":"101915906 DCUN1D1; defective in cullin neddylation 1 domain containing 1\tK17822 DCUN1D1_2; DCN1-like protein 1\/2"
			},
			{
				"name":"101918770 DCUN1D3; defective in cullin neddylation 1 domain containing 3\tK17823 DCUN1D3; DCN1-like protein 3"
			},
			{
				"name":"101913981 DCUN1D5; defective in cullin neddylation 1 domain containing 5\tK17824 DCUN1D4_5; DCN1-like protein 4\/5"
			},
			{
				"name":"101914211 DCUN1D4; defective in cullin neddylation 1 domain containing 4\tK17824 DCUN1D4_5; DCN1-like protein 4\/5"
			}
			]
		},
		{
			"name":"Multi subunit type E3",
			"children":[
			{
				"name":"SCF complex",
				"children":[
				{
					"name":"Ring finger protein",
					"children":[
					{
						"name":"101916874 RBX1; ring-box 1\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
					}
					]
				},
				{
					"name":"Cullin",
					"children":[
					{
						"name":"101911159 CUL1; cullin 1\tK03347 CUL1; cullin 1"
					}
					]
				},
				{
					"name":"Adaptor protein",
					"children":[
					{
						"name":"101911889 SKP1; S-phase kinase associated protein 1\tK03094 SKP1; S-phase kinase-associated protein 1"
					}
					]
				},
				{
					"name":"Target recognizing subunit (F-box)",
					"children":[
					{
						"name":"101914153 FBXW11; F-box and WD repeat domain containing 11\tK03362 FBXW1_11; F-box and WD-40 domain protein 1\/11"
					},
					{
						"name":"101920782 BTRC; beta-transducin repeat containing E3 ubiquitin protein ligase\tK03362 FBXW1_11; F-box and WD-40 domain protein 1\/11"
					},
					{
						"name":"101924593 FBXW2; F-box and WD repeat domain containing 2\tK10261 FBXW2; F-box and WD-40 domain protein 2"
					},
					{
						"name":"101920430 FBXW4; F-box and WD repeat domain containing 4\tK10262 FBXW4; F-box and WD-40 domain protein 4"
					},
					{
						"name":"101916505 FBXW5; F-box and WD repeat domain containing 5\tK10263 FBXW5; F-box and WD-40 domain protein 5"
					},
					{
						"name":"101910281 FBXW7; F-box and WD repeat domain containing 7\tK10260 FBXW7; F-box and WD-40 domain protein 7"
					},
					{
						"name":"101919228 F-box\/WD repeat-containing protein 7-like\tK10260 FBXW7; F-box and WD-40 domain protein 7"
					},
					{
						"name":"101924554 FBXW8; F-box and WD repeat domain containing 8\tK10264 FBXW8; F-box and WD-40 domain protein 8"
					},
					{
						"name":"101914274 FBXW9; F-box and WD repeat domain containing 9\tK10265 FBXW9; F-box and WD-40 domain protein 9"
					},
					{
						"name":"101920058 CDRT1; CMT1A duplicated region transcript 1\tK10266 FBXW10; F-box and WD-40 domain protein 10"
					},
					{
						"name":"101911609 SKP2; S-phase kinase associated protein 2\tK03875 SKP2; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)"
					},
					{
						"name":"101917425 FBXL2; F-box and leucine rich repeat protein 2\tK10268 FBXL2_20; F-box and leucine-rich repeat protein 2\/20"
					},
					{
						"name":"101922935 FBXL20; F-box and leucine rich repeat protein 20\tK10268 FBXL2_20; F-box and leucine-rich repeat protein 2\/20"
					},
					{
						"name":"101916408 FBXL3; F-box and leucine rich repeat protein 3\tK10269 FBXL3; F-box and leucine-rich repeat protein 3"
					},
					{
						"name":"101916022 FBXL4; F-box and leucine rich repeat protein 4\tK10270 FBXL4; F-box and leucine-rich repeat protein 4"
					},
					{
						"name":"101918145 FBXL5; F-box and leucine rich repeat protein 5\tK10271 FBXL5; F-box and leucine-rich repeat protein 5"
					},
					{
						"name":"101915681 FBXL7; F-box and leucine rich repeat protein 7\tK10273 FBXL7; F-box and leucine-rich repeat protein 7"
					},
					{
						"name":"101921663 FBXL8; F-box and leucine rich repeat protein 8\tK10274 FBXL8; F-box and leucine-rich repeat protein 8"
					},
					{
						"name":"101912390 KDM2B; lysine demethylase 2B\tK10276 FBXL10_11; F-box and leucine-rich repeat protein 10\/11 [EC:1.14.11.27]"
					},
					{
						"name":"101914594 KDM2A; lysine demethylase 2A\tK10276 FBXL10_11; F-box and leucine-rich repeat protein 10\/11 [EC:1.14.11.27]"
					},
					{
						"name":"101924600 FBXL12; F-box and leucine rich repeat protein 12\tK10278 FBXL12; F-box and leucine-rich repeat protein 12"
					},
					{
						"name":"101911127 FBXL13; F-box and leucine rich repeat protein 13\tK10279 FBXL13; dynein regulatory complex subunit 6"
					},
					{
						"name":"101915465 FBXL14; F-box and leucine rich repeat protein 14\tK10280 FBXL14; F-box and leucine-rich repeat protein 14"
					},
					{
						"name":"101924993 FBXL15; F-box and leucine rich repeat protein 15\tK10281 FBXL15; F-box and leucine-rich repeat protein 15"
					},
					{
						"name":"101913852 FBXL16; F-box and leucine rich repeat protein 16\tK10282 FBXL16; F-box and leucine-rich repeat protein 16"
					},
					{
						"name":"101915530 FBXL17; F-box and leucine rich repeat protein 17\tK10283 FBXL17; F-box and leucine-rich repeat protein 17"
					},
					{
						"name":"106112233 F-box\/LRR-repeat protein 17-like\tK10283 FBXL17; F-box and leucine-rich repeat protein 17"
					},
					{
						"name":"101912535 FBXL18; F-box and leucine rich repeat protein 18\tK10284 FBXL18; F-box and leucine-rich repeat protein 18"
					},
					{
						"name":"101924806 FBXL21; F-box and leucine rich repeat protein 21\tK10287 FBXL21; F-box and leucine-rich repeat protein 21"
					},
					{
						"name":"101910887 FBXL22; F-box and leucine rich repeat protein 22\tK10288 FBXL22; F-box and leucine-rich repeat protein 22"
					},
					{
						"name":"101917828 CCNF; cyclin F\tK10289 CCNF; F-box protein 1 (cyclin F)"
					},
					{
						"name":"101919978 FBXO2; F-box only protein 2\tK10099 FBXO2; F-box protein 2"
					},
					{
						"name":"101919378 FBXO3; F-box protein 3\tK10290 FBXO3; F-box protein 3"
					},
					{
						"name":"101924235 FBXO4; F-box protein 4\tK10291 FBXO4; F-box protein 4"
					},
					{
						"name":"101918016 FBXO5; F-box protein 5\tK10292 FBXO5; F-box protein 5"
					},
					{
						"name":"101912079 FBXO6; F-box only protein 6\tK10100 FBXO6; F-box protein 6"
					},
					{
						"name":"101916665 FBXO7; F-box protein 7\tK10293 FBXO7; F-box protein 7"
					},
					{
						"name":"101917417 FBXO8; F-box protein 8\tK10294 FBXO8; F-box protein 8"
					},
					{
						"name":"101910358 FBXO9; F-box protein 9\tK10295 FBXO9; F-box protein 9"
					},
					{
						"name":"101923401 FBXO10; F-box protein 10\tK10296 FBXO10; F-box protein 10"
					},
					{
						"name":"101921883 FBXO11; F-box protein 11\tK10297 FBXO11; F-box protein 11"
					},
					{
						"name":"101915177 FBXO15; F-box protein 15\tK10298 FBXO15; F-box protein 15"
					},
					{
						"name":"101917579 FBXO16; F-box protein 16\tK10299 FBXO16; F-box protein 16"
					},
					{
						"name":"101911387 FBXO18; F-box protein, helicase, 18\tK10300 FBH1; F-box DNA helicase 1 [EC:5.6.2.4]"
					},
					{
						"name":"101919018 LMO7; LIM domain 7\tK06084 LMO7; F-box protein 20"
					},
					{
						"name":"101917034 FBXO21; F-box protein 21\tK10301 FBXO21; F-box protein 21"
					},
					{
						"name":"101923993 FBXO22; F-box protein 22\tK10302 FBXO22; F-box protein 22"
					},
					{
						"name":"101912510 FBXO25; F-box protein 25\tK10305 FBXO25_32; F-box protein 25\/32"
					},
					{
						"name":"101918879 FBXO32; F-box protein 32\tK10305 FBXO25_32; F-box protein 25\/32"
					},
					{
						"name":"101919786 FBXO28; F-box protein 28\tK10306 FBXO28; F-box protein 28"
					},
					{
						"name":"101921092 FBXO30; F-box protein 30\tK10307 FBXO30; F-box protein 30"
					},
					{
						"name":"101917279 FBXO31; F-box protein 31\tK10308 FBXO31; F-box protein 31"
					},
					{
						"name":"101918241 FBXO33; F-box protein 33\tK10310 FBXO33; F-box protein 33"
					},
					{
						"name":"101924808 FBXO34; F-box protein 34\tK10311 FBXO34; F-box protein 34"
					},
					{
						"name":"101923646 FBXO36; F-box protein 36\tK10312 FBXO36; F-box protein 36"
					},
					{
						"name":"101920340 FBXO38; F-box protein 38\tK10313 FBXO38; F-box protein 38"
					},
					{
						"name":"101920932 FBXO39; F-box protein 39\tK10314 FBXO39; F-box protein 39"
					},
					{
						"name":"101916923 FBXO40; F-box protein 40\tK10315 FBXO40; F-box protein 40"
					},
					{
						"name":"101912337 FBXO41; F-box protein 41\tK10316 FBXO41; F-box protein 41"
					},
					{
						"name":"101911194 FBXO42; F-box protein 42\tK10317 FBXO42; F-box protein 42"
					},
					{
						"name":"101911434 FBXO43; F-box protein 43\tK10318 FBXO43; F-box protein 43"
					},
					{
						"name":"101920066 FBXO46; F-box protein 46\tK10320 FBXO46; F-box protein 46"
					},
					{
						"name":"101915614 FBXO47; F-box protein 47\tK10321 FBXO47; F-box protein 47"
					},
					{
						"name":"101923807 FBXO48; F-box protein 48\tK27313 FBXO48; F-box protein 48"
					}
					]
				}
				]
			},
			{
				"name":"Cul2 complex",
				"children":[
				{
					"name":"Ring finger protein",
					"children":[
					{
						"name":"101916874 RBX1; ring-box 1\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
					}
					]
				},
				{
					"name":"Cullin",
					"children":[
					{
						"name":"101923525 CUL2; cullin 2\tK03870 CUL2; cullin 2"
					}
					]
				},
				{
					"name":"Adoptor protein",
					"children":[
					{
						"name":"101910616 ELOC; elongin C\tK03872 ELOC; elongin-C"
					}
					]
				},
				{
					"name":"Target recognizing subunit",
					"children":[
					{
						"name":"101921920 VHL; von Hippel-Lindau tumor suppressor\tK03871 VHL; von Hippel-Lindau disease tumor supressor"
					},
					{
						"name":"101914087 LRR1; leucine rich repeat protein 1\tK10348 LRR1; LRR-repeat protein 1"
					},
					{
						"name":"101914476 FEM1C; fem-1 homolog C\tK25805 FEM1A_C; protein fem-1 homolog A\/C"
					},
					{
						"name":"101921070 FEM1A; fem-1 homolog A\tK25805 FEM1A_C; protein fem-1 homolog A\/C"
					},
					{
						"name":"101911748 FEM1B; fem-1 homolog B\tK10349 FEM1B; protein fem-1 homolog B"
					},
					{
						"name":"101912207 APPBP2; amyloid beta precursor protein binding protein 2\tK25806 APPBP2; amyloid protein-binding protein 2"
					},
					{
						"name":"101911313 KLHDC2; kelch domain containing 2\tK25807 KLHDC2; kelch domain-containing protein 2"
					},
					{
						"name":"101918646 KLHDC3; kelch domain containing 3\tK25808 KLHDC3; kelch domain-containing protein 3"
					},
					{
						"name":"101910695 KLHDC10; kelch domain containing 10\tK25809 KLHDC10; kelch domain-containing protein 10"
					},
					{
						"name":"101917025 ZYG11B; protein zyg-11 homolog B\tK10350 ZYG11; Zyg-11 protein"
					},
					{
						"name":"101924436 ZER1; zyg-11 related cell cycle regulator\tK10350 ZYG11; Zyg-11 protein"
					},
					{
						"name":"101915023 ZSWIM8; zinc finger SWIM-type containing 8\tK25207 ZSWIM8; zinc finger SWIM domain-containing protein 8"
					}
					]
				}
				]
			},
			{
				"name":"Cul3 complex",
				"children":[
				{
					"name":"Ring finger protein",
					"children":[
					{
						"name":"101916874 RBX1; ring-box 1\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
					}
					]
				},
				{
					"name":"Cullin",
					"children":[
					{
						"name":"101921145 CUL3; cullin 3\tK03869 CUL3; cullin 3"
					}
					]
				},
				{
					"name":"Adoptor and target recognizing subunit (BTB)",
					"children":[
					{
						"name":"101913796 KLHL5; kelch like family member 5\tK10442 KLHL1_4_5; kelch-like protein 1\/4\/5"
					},
					{
						"name":"101917407 KLHL4; kelch like family member 4\tK10442 KLHL1_4_5; kelch-like protein 1\/4\/5"
					},
					{
						"name":"101920578 KLHL1; kelch-like protein 1\tK10442 KLHL1_4_5; kelch-like protein 1\/4\/5"
					},
					{
						"name":"101914374 KLHL2; kelch like family member 2\tK10443 KLHL2_3; kelch-like protein 2\/3"
					},
					{
						"name":"101923839 KLHL3; kelch like family member 3\tK10443 KLHL2_3; kelch-like protein 2\/3"
					},
					{
						"name":"101911316 KLHL6; kelch like family member 6\tK10444 KLHL6; kelch-like protein 6"
					},
					{
						"name":"101910814 KLHL7; kelch like family member 7\tK10445 KLHL7; kelch-like protein 7"
					},
					{
						"name":"101916794 KLHL8; kelch like family member 8\tK10446 KLHL8; kelch-like protein 8"
					},
					{
						"name":"101915198 KLHL13; kelch like family member 13\tK10447 KLHL9_13; kelch-like protein 9\/13"
					},
					{
						"name":"106112076 kelch-like protein 9\tK10447 KLHL9_13; kelch-like protein 9\/13"
					},
					{
						"name":"101913847 KLHL12; kelch like family member 12\tK10450 KLHL12; kelch-like protein 12"
					},
					{
						"name":"101912119 KLHL14; kelch like family member 14\tK10451 KLHL14; kelch-like protein 14"
					},
					{
						"name":"101921952 KLHL15; kelch like family member 15\tK10452 KLHL15; kelch-like protein 15"
					},
					{
						"name":"101915730 GAN; gigaxonin\tK10453 KLHL16; kelch-like protein 16 (gigaxonin)"
					},
					{
						"name":"101915100 KLHL17; kelch like family member 17\tK10454 KLHL17; kelch-like protein 17 (actinfilin)"
					},
					{
						"name":"101914312 KLHL18; kelch like family member 18\tK10455 KLHL18; kelch-like protein 18"
					},
					{
						"name":"101913139 KEAP1; kelch like ECH associated protein 1\tK10456 KLHL19; kelch-like protein 19"
					},
					{
						"name":"101918023 KLHL20; kelch like family member 20\tK10457 KLHL20; kelch-like protein 20"
					},
					{
						"name":"101916708 KLHL21; kelch like family member 21\tK10458 KLHL21; kelch-like protein 21"
					},
					{
						"name":"101910978 KLHL22; kelch like family member 22\tK10459 KLHL22; kelch-like protein 22"
					},
					{
						"name":"101922022 KLHL23; kelch like family member 23\tK10460 KLHL23; kelch-like protein 23"
					},
					{
						"name":"101911145 KLHL24; kelch like family member 24\tK10461 KLHL24_35; kelch-like protein 24\/35"
					},
					{
						"name":"101923036 KLHL35; kelch like family member 35\tK10461 KLHL24_35; kelch-like protein 24\/35"
					},
					{
						"name":"101912647 KLHL25; kelch like family member 25\tK10462 KLHL25_37; kelch-like protein 25\/37 (ectoderm-neural cortex protein)"
					},
					{
						"name":"101914894 ectoderm-neural cortex protein 1-like\tK10462 KLHL25_37; kelch-like protein 25\/37 (ectoderm-neural cortex protein)"
					},
					{
						"name":"101915069 ENC1; ectodermal-neural cortex 1\tK10462 KLHL25_37; kelch-like protein 25\/37 (ectoderm-neural cortex protein)"
					},
					{
						"name":"101921619 KLHL26; kelch like family member 26\tK10463 KLHL26; kelch-like protein 26"
					},
					{
						"name":"101913099 IPP; intracisternal A particle-promoted polypeptide\tK13956 IPP; actin-binding protein IPP"
					},
					{
						"name":"101923438 KLHL28; kelch like family member 28\tK10464 KLHL28; kelch-like protein 28"
					},
					{
						"name":"101920152 KLHL29; kelch like family member 29\tK10465 KLHL29; kelch-like protein 29"
					},
					{
						"name":"101910991 KLHL30; kelch like family member 30\tK10466 KLHL30; kelch-like protein 30"
					},
					{
						"name":"101924438 kelch-like protein 31\tK10467 KLHL31; kelch-like protein 31"
					},
					{
						"name":"101924620 KLHL31; kelch like family member 31\tK10467 KLHL31; kelch-like protein 31"
					},
					{
						"name":"101916361 KLHL32; kelch like family member 32\tK10468 KLHL32; kelch-like protein 32"
					},
					{
						"name":"101912151 KLHL33; kelch like family member 33\tK13957 KLHL33; kelch-like protein 33"
					},
					{
						"name":"101923384 KLHL34; kelch like family member 34\tK10469 KLHL34; kelch-like protein 34"
					},
					{
						"name":"101912840 KLHL36; kelch like family member 36\tK13958 KLHL36; kelch-like protein 36"
					},
					{
						"name":"101919385 KLHL38; kelch like family member 38\tK13959 KLHL38; kelch-like protein 38"
					},
					{
						"name":"101910924 KLHL42; kelch like family member 42\tK27973 KLHL42; kelch-like protein 42"
					},
					{
						"name":"101917068 KBTBD2; kelch repeat and BTB domain containing 2\tK10470 KBTBD2; kelch repeat and BTB domain-containing protein 2"
					},
					{
						"name":"101913991 KBTBD3; kelch repeat and BTB domain containing 3\tK10471 KBTBD3; kelch repeat and BTB domain-containing protein 3"
					},
					{
						"name":"101910828 KBTBD4; kelch repeat and BTB domain containing 4\tK10472 KBTBD4; kelch repeat and BTB domain-containing protein 4"
					},
					{
						"name":"101921337 KLHL41; kelch like family member 41\tK10473 KBTBD5_10; kelch repeat and BTB domain-containing protein 5\/10"
					},
					{
						"name":"101923378 KLHL40; kelch like family member 40\tK10473 KBTBD5_10; kelch repeat and BTB domain-containing protein 5\/10"
					},
					{
						"name":"101923799 KBTBD8; kelch repeat and BTB domain containing 8\tK10475 KBTBD8; kelch repeat and BTB domain-containing protein 8"
					},
					{
						"name":"101920998 KBTBD11; kelch repeat and BTB domain containing 11\tK10476 KBTBD11; kelch repeat and BTB domain-containing protein 11"
					},
					{
						"name":"101916331 KBTBD12; kelch repeat and BTB domain containing 12\tK21912 KBTBD12; kelch repeat and BTB domain-containing protein 12"
					},
					{
						"name":"101920024 KBTBD13; kelch repeat and BTB domain containing 13\tK21913 KBTBD13; kelch repeat and BTB domain-containing protein 13"
					},
					{
						"name":"101916546 BTBD1; BTB domain containing 1\tK10477 BTBD1_2; BTB\/POZ domain-containing protein 1\/2"
					},
					{
						"name":"101917691 BTBD2; BTB domain containing 2\tK10477 BTBD1_2; BTB\/POZ domain-containing protein 1\/2"
					},
					{
						"name":"101911238 BTB\/POZ domain-containing protein 6-like\tK10478 BTBD3_6; BTB\/POZ domain-containing protein 3\/6"
					},
					{
						"name":"101917931 BTBD3; BTB domain containing 3\tK10478 BTBD3_6; BTB\/POZ domain-containing protein 3\/6"
					},
					{
						"name":"101915289 BTBD7; BTB domain containing 7\tK10479 BTBD7; BTB\/POZ domain-containing protein 7"
					},
					{
						"name":"101916764 KIAA1107 ortholog\tK10480 BTBD8; BTB\/POZ domain-containing protein 8"
					},
					{
						"name":"101914702 BTBD9; BTB domain containing 9\tK10481 BTBD9; BTB\/POZ domain-containing protein 9"
					},
					{
						"name":"101921031 BTBD10; BTB domain containing 10\tK10482 BTBD10; BTB\/POZ domain-containing protein 10"
					},
					{
						"name":"101921166 BTBD11; BTB domain containing 11\tK10483 BTBD11; BTB\/POZ domain-containing protein 11"
					},
					{
						"name":"101921938 SLX4; SLX4 structure-specific endonuclease subunit\tK10484 BTBD12; structure-specific endonuclease subunit SLX4 (BTB\/POZ domain-containing protein 12)"
					},
					{
						"name":"101912211 GMCL1; germ cell-less, spermatogenesis associated 1\tK10485 BTBD13; BTB\/POZ domain-containing protein 13 (germ cell-less protein-like 1)"
					},
					{
						"name":"101910911 NACC2; NACC family member 2\tK10486 BTBD14; BTB\/POZ domain-containing protein 14"
					},
					{
						"name":"101919019 NACC1; nucleus accumbens associated 1\tK10486 BTBD14; BTB\/POZ domain-containing protein 14"
					},
					{
						"name":"101910483 ZBTB1; zinc finger and BTB domain containing 1\tK10488 ZBTB1; zinc finger and BTB domain-containing protein 1"
					},
					{
						"name":"101918715 ZBTB2; zinc finger and BTB domain containing 2\tK10489 ZBTB2; zinc finger and BTB domain-containing protein 2"
					},
					{
						"name":"101923578 ZBTB5; zinc finger and BTB domain containing 5\tK10492 ZBTB5; zinc finger and BTB domain-containing protein 5"
					},
					{
						"name":"101919696 ZBTB6; zinc finger and BTB domain containing 6\tK10493 ZBTB6; zinc finger and BTB domain-containing protein 6"
					},
					{
						"name":"101918844 ZBTB7C; zinc finger and BTB domain containing 7C\tK10494 ZBTB7; zinc finger and BTB domain-containing protein 7"
					},
					{
						"name":"101919217 ZBTB7A; zinc finger and BTB domain containing 7A\tK10494 ZBTB7; zinc finger and BTB domain-containing protein 7"
					},
					{
						"name":"101918811 zinc finger and BTB domain-containing protein 8A-like\tK10495 ZBTB8; zinc finger and BTB domain-containing protein 8"
					},
					{
						"name":"101919089 zinc finger and BTB domain-containing protein 8A-like\tK10495 ZBTB8; zinc finger and BTB domain-containing protein 8"
					},
					{
						"name":"101924405 ZBTB8B; zinc finger and BTB domain containing 8B\tK10495 ZBTB8; zinc finger and BTB domain-containing protein 8"
					},
					{
						"name":"101920284 ZBTB9; zinc finger and BTB domain containing 9\tK10496 ZBTB9; zinc finger and BTB domain-containing protein 9"
					},
					{
						"name":"101921752 ZBTB10; zinc finger and BTB domain containing 10\tK10497 ZBTB10; zinc finger and BTB domain-containing protein 10"
					},
					{
						"name":"101917518 ZBTB11; zinc finger and BTB domain containing 11\tK10498 ZBTB11; zinc finger and BTB domain-containing protein 11"
					},
					{
						"name":"101923073 ZBTB16; zinc finger and BTB domain containing 16\tK10055 ZBTB16; zinc finger and BTB domain-containing protein 16"
					},
					{
						"name":"101919338 ZBTB17; zinc finger and BTB domain containing 17\tK10500 ZBTB17; zinc finger and BTB domain-containing protein 17"
					},
					{
						"name":"101922198 ZBTB20; zinc finger and BTB domain containing 20\tK10501 ZBTB20; zinc finger and BTB domain-containing protein 20"
					},
					{
						"name":"101911300 ZBTB24; zinc finger and BTB domain containing 24\tK10503 ZBTB24; zinc finger and BTB domain-containing protein 24"
					},
					{
						"name":"101910307 ZBTB25; zinc finger and BTB domain containing 25\tK10504 ZBTB25; zinc finger and BTB domain-containing protein 25"
					},
					{
						"name":"101917377 ZBTB26; zinc finger and BTB domain containing 26\tK10505 ZBTB26; zinc finger and BTB domain-containing protein 26"
					},
					{
						"name":"101924852 ZBTB33; zinc finger and BTB domain containing 33\tK10507 ZBTB33; zinc finger and BTB domain-containing protein 33"
					},
					{
						"name":"101910507 ZBTB34; zinc finger and BTB domain containing 34\tK10508 ZBTB34; zinc finger and BTB domain-containing protein 34"
					},
					{
						"name":"101915259 ZBTB37; zinc finger and BTB domain containing 37\tK10509 ZBTB37; zinc finger and BTB domain-containing protein 37"
					},
					{
						"name":"101912329 ZBTB38; zinc finger and BTB domain containing 38\tK10510 ZBTB38; zinc finger and BTB domain-containing protein 38"
					},
					{
						"name":"101915096 ZBTB39; zinc finger and BTB domain containing 39\tK10511 ZBTB39; zinc finger and BTB domain-containing protein 39"
					},
					{
						"name":"101914701 ZBTB40; zinc finger and BTB domain containing 40\tK10512 ZBTB40; zinc finger and BTB domain-containing protein 40"
					},
					{
						"name":"101918413 ZBTB41; zinc finger and BTB domain containing 41\tK10513 ZBTB41; zinc finger and BTB domain-containing protein 41"
					},
					{
						"name":"101910680 ZBTB43; zinc finger and BTB domain containing 43\tK10514 ZBTB43; zinc finger and BTB domain-containing protein 43"
					},
					{
						"name":"101919308 ZBTB44; zinc finger and BTB domain containing 44\tK10515 ZBTB44; zinc finger and BTB domain-containing protein 44"
					},
					{
						"name":"101912493 ZBTB45; zinc finger and BTB domain containing 45\tK10516 ZBTB45; zinc finger and BTB domain-containing protein 45"
					},
					{
						"name":"101922088 ZBTB46; zinc finger and BTB domain containing 46\tK10517 ZBTB46; zinc finger and BTB domain-containing protein 46"
					},
					{
						"name":"101923205 ZBTB47; zinc finger and BTB domain containing 47\tK10518 ZBTB47; zinc finger and BTB domain-containing protein 47"
					},
					{
						"name":"101916878 ZBTB48; zinc finger and BTB domain containing 48\tK10519 ZBTB48; zinc finger and BTB domain-containing protein 48"
					},
					{
						"name":"101915987 ABTB1; ankyrin repeat and BTB domain containing 1\tK10520 ABTB1; ankyrin repeat and BTB\/POZ domain-containing protein 1"
					},
					{
						"name":"101919554 ABTB2; ankyrin repeat and BTB domain containing 2\tK10521 ABTB2; ankyrin repeat and BTB\/POZ domain-containing protein 2"
					},
					{
						"name":"101911153 RHOBTB2; Rho related BTB domain containing 2\tK07868 RHOBTB1_2; Rho-related BTB domain-containing protein 1\/2"
					},
					{
						"name":"101912744 RHOBTB1; Rho related BTB domain containing 1\tK07868 RHOBTB1_2; Rho-related BTB domain-containing protein 1\/2"
					},
					{
						"name":"101924848 rho-related BTB domain-containing protein 2\tK07868 RHOBTB1_2; Rho-related BTB domain-containing protein 1\/2"
					},
					{
						"name":"101914108 RHOBTB3; Rho related BTB domain containing 3\tK07869 RHOBTB3; Rho-related BTB domain-containing protein 3"
					},
					{
						"name":"101910530 KCTD10; potassium channel tetramerization domain containing 10\tK15074 BACURD; BTB\/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein"
					},
					{
						"name":"101915494 TNFAIP1; TNF alpha induced protein 1\tK15074 BACURD; BTB\/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein"
					},
					{
						"name":"101911298 KCTD1; potassium channel tetramerization domain containing 1\tK21754 KCTD1_15; BTB\/POZ domain-containing protein KCTD1\/15"
					},
					{
						"name":"101919687 KCTD15; potassium channel tetramerization domain containing 15\tK21754 KCTD1_15; BTB\/POZ domain-containing protein KCTD1\/15"
					},
					{
						"name":"101923833 KCTD5; BTB\/POZ domain-containing protein KCTD5\tK21914 KCTD2_5_17; BTB\/POZ domain-containing protein KCTD2\/5\/17"
					},
					{
						"name":"101924647 KCTD2; potassium channel tetramerization domain containing 2\tK21914 KCTD2_5_17; BTB\/POZ domain-containing protein KCTD2\/5\/17"
					},
					{
						"name":"101924108 KCTD3; potassium channel tetramerization domain containing 3\tK21915 KCTD3; BTB\/POZ domain-containing protein KCTD3"
					},
					{
						"name":"101910905 KCTD6; potassium channel tetramerization domain containing 6\tK21916 KCTD6; BTB\/POZ domain-containing protein KCTD6"
					},
					{
						"name":"101919379 KCTD7; potassium channel tetramerization domain containing 7\tK21917 KCTD7_14; BTB\/POZ domain-containing protein KCTD7\/14"
					},
					{
						"name":"101923978 KCTD14; potassium channel tetramerization domain containing 14\tK21917 KCTD7_14; BTB\/POZ domain-containing protein KCTD7\/14"
					},
					{
						"name":"101918849 KCTD12; potassium channel tetramerization domain containing 12\tK21918 KCTD8_12_16; BTB\/POZ domain-containing protein KCTD8\/12\/16"
					},
					{
						"name":"101921788 KCTD16; potassium channel tetramerization domain containing 16\tK21918 KCTD8_12_16; BTB\/POZ domain-containing protein KCTD8\/12\/16"
					},
					{
						"name":"101922531 BTB\/POZ domain-containing protein KCTD12-like\tK21918 KCTD8_12_16; BTB\/POZ domain-containing protein KCTD8\/12\/16"
					},
					{
						"name":"101923864 KCTD8; potassium channel tetramerization domain containing 8\tK21918 KCTD8_12_16; BTB\/POZ domain-containing protein KCTD8\/12\/16"
					},
					{
						"name":"101917736 KCTD9; potassium channel tetramerization domain containing 9\tK21919 KCTD9; BTB\/POZ domain-containing protein KCTD9"
					},
					{
						"name":"101915482 KCTD18; potassium channel tetramerization domain containing 18\tK21921 KCTD18; BTB\/POZ domain-containing protein KCTD18"
					},
					{
						"name":"101920811 KCTD21; BTB\/POZ domain-containing protein KCTD21\tK21922 KCTD21; BTB\/POZ domain-containing protein KCTD21"
					},
					{
						"name":"106112270 BTB\/POZ domain-containing protein KCTD21\tK21922 KCTD21; BTB\/POZ domain-containing protein KCTD21"
					},
					{
						"name":"101911517 DIABLO; diablo IAP-binding mitochondrial protein\tK10522 DIABLO; diablo"
					},
					{
						"name":"101911274 SPOP; speckle type BTB\/POZ protein\tK10523 SPOP; speckle-type POZ protein"
					},
					{
						"name":"101917004 SPOPL; speckle type BTB\/POZ protein like\tK10523 SPOP; speckle-type POZ protein"
					},
					{
						"name":"101914350 LZTR1; leucine zipper like transcription regulator 1\tK23330 LZTR1; leucine-zipper-like transcriptional regulator 1"
					}
					]
				}
				]
			},
			{
				"name":"Cul4 complex",
				"children":[
				{
					"name":"Ring finger protein",
					"children":[
					{
						"name":"101916874 RBX1; ring-box 1\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
					}
					]
				},
				{
					"name":"Cullin",
					"children":[
					{
						"name":"101910426 CUL4B; cullin 4B\tK10609 CUL4; cullin 4"
					},
					{
						"name":"101923321 CUL4A; cullin 4A\tK10609 CUL4; cullin 4"
					}
					]
				},
				{
					"name":"Adoptor protein",
					"children":[
					{
						"name":"101916555 DDB1; damage specific DNA binding protein 1\tK10610 DDB1; DNA damage-binding protein 1"
					}
					]
				},
				{
					"name":"Target recognizing subunit (DCAF)",
					"children":[
					{
						"name":"101911160 DDB2; damage specific DNA binding protein 2\tK10140 DDB2; DNA damage-binding protein 2"
					},
					{
						"name":"101920833 ERCC8; ERCC excision repair 8, CSA ubiquitin ligase complex subunit\tK10570 ERCC8; DNA excision repair protein ERCC-8"
					},
					{
						"name":"101911774 DET1; de-etiolated homolog 1 (Arabidopsis)\tK10571 DET1; de-etiolated-1"
					},
					{
						"name":"101924035 RFWD2; ring finger and WD repeat domain 2\tK10143 RFWD2; E3 ubiquitin-protein ligase RFWD2 [EC:2.3.2.27]"
					},
					{
						"name":"101917315 DDA1; DET1 and DDB1 associated 1\tK11792 DDA1; DET1- and DDB1-associated protein 1"
					},
					{
						"name":"101920550 CRBN; cereblon\tK11793 CRBN; cereblon"
					},
					{
						"name":"101924205 TRPC4AP; transient receptor potential cation channel subfamily C member 4 associated protein\tK11796 TRPC4AP; Trpc4-associated protein"
					},
					{
						"name":"101917371 DCAF1; DDB1 and CUL4 associated factor 1\tK11789 DCAF1; DDB1- and CUL4-associated factor 1 [EC:2.7.11.1]"
					},
					{
						"name":"101919602 DTL; denticleless E3 ubiquitin protein ligase homolog\tK11790 DTL; denticleless"
					},
					{
						"name":"101921363 DCAF4; DDB1 and CUL4 associated factor 4\tK11799 DCAF4; DDB1- and CUL4-associated factor 4"
					},
					{
						"name":"101912259 DCAF5; DDB1 and CUL4 associated factor 5\tK11800 DCAF5; DDB1- and CUL4-associated factor 5"
					},
					{
						"name":"101917282 DCAF6; DDB1 and CUL4 associated factor 6\tK11795 DCAF6; DDB1- and CUL4-associated factor 6"
					},
					{
						"name":"101923764 DCAF7; DDB1 and CUL4 associated factor 7\tK11805 DCAF7; DDB1- and CUL4-associated factor 7"
					},
					{
						"name":"101915539 DCAF8; DDB1 and CUL4 associated factor 8\tK11804 DCAF8; DDB1- and CUL4-associated factor 8"
					},
					{
						"name":"101921801 WDTC1; WD and tetratricopeptide repeats 1\tK11807 WDTC1; WD and tetratricopeptide repeats protein 1"
					},
					{
						"name":"101911753 DCAF10; DDB1 and CUL4 associated factor 10\tK11802 DCAF10; DDB1- and CUL4-associated factor 10"
					},
					{
						"name":"101925012 DCAF12; DDB1 and CUL4 associated factor 12\tK11803 DCAF12; DDB1- and CUL4-associated factor 12"
					},
					{
						"name":"101917894 DCAF13; DDB1 and CUL4 associated factor 13\tK11806 DCAF13; DDB1- and CUL4-associated factor 13"
					},
					{
						"name":"101920328 PHIP; pleckstrin homology domain interacting protein\tK11797 PHIP; PH-interacting protein"
					},
					{
						"name":"101914575 DCAF17; DDB1 and CUL4 associated factor 17\tK23331 DCAF17; DDB1- and CUL4-associated factor 17"
					},
					{
						"name":"101916149 BRWD3; bromodomain and WD repeat domain containing 3\tK11798 BRWD1_3; bromodomain and WD repeat domain containing protein 1\/3"
					},
					{
						"name":"101920679 BRWD1; bromodomain and WD repeat domain containing 1\tK11798 BRWD1_3; bromodomain and WD repeat domain containing protein 1\/3"
					},
					{
						"name":"101915641 WDR26; WD repeat domain 26\tK22382 WDR26; WD repeat-containing protein 26"
					},
					{
						"name":"101922164 WDR70; WD repeat domain 70\tK24752 WDR70; WD repeat-containing protein 70"
					},
					{
						"name":"101922490 WDR76; WD repeat domain 76\tK24755 WDR76; WD repeat-containing protein 76"
					}
					]
				}
				]
			},
			{
				"name":"Cul5 complex",
				"children":[
				{
					"name":"Ring finger protein"
				},
				{
					"name":"Cullin",
					"children":[
					{
						"name":"101920396 CUL5; cullin 5\tK10612 CUL5; cullin 5"
					}
					]
				},
				{
					"name":"Adoptor protein",
					"children":[
					{
						"name":"101910616 ELOC; elongin C\tK03872 ELOC; elongin-C"
					}
					]
				},
				{
					"name":"Target recognizing subunit",
					"children":[
					{
						"name":"101918904 CISH; cytokine inducible SH2 containing protein\tK04701 CISH; cytokine inducible SH2-containing protein"
					},
					{
						"name":"101912887 SOCS1; suppressor of cytokine signaling 1\tK04694 SOCS1; suppressor of cytokine signaling 1"
					},
					{
						"name":"106112815 SOCS2; suppressor of cytokine signaling 2\tK04695 SOCS2; suppressor of cytokine signaling 2"
					},
					{
						"name":"101912299 SOCS3; suppressor of cytokine signaling 3\tK04696 SOCS3; suppressor of cytokine signaling 3"
					},
					{
						"name":"101924304 SOCS4; suppressor of cytokine signaling 4\tK04697 SOCS4; suppressor of cytokine signaling 4"
					},
					{
						"name":"101917293 SOCS5; suppressor of cytokine signaling 5\tK04698 SOCS5; suppressor of cytokine signaling 5"
					},
					{
						"name":"101916349 SOCS6; suppressor of cytokine signaling 6\tK04699 SOCS6_7; suppressor of cytokine signaling 6\/7"
					},
					{
						"name":"101922713 SOCS7; suppressor of cytokine signaling 7\tK04699 SOCS6_7; suppressor of cytokine signaling 6\/7"
					},
					{
						"name":"101924408 ASB1; ankyrin repeat and SOCS box containing 1\tK10323 ASB1; ankyrin repeat and SOCS box protein 1"
					},
					{
						"name":"101915805 ASB2; ankyrin repeat and SOCS box containing 2\tK10324 ASB2; ankyrin repeat and SOCS box protein 2"
					},
					{
						"name":"101917919 ASB3; ankyrin repeat and SOCS box containing 3\tK10325 ASB3; ankyrin repeat and SOCS box protein 3"
					},
					{
						"name":"101922279 ASB4; ankyrin repeat and SOCS box containing 4\tK10326 ASB4; ankyrin repeat and SOCS box protein 4"
					},
					{
						"name":"101912804 ASB5; ankyrin repeat and SOCS box containing 5\tK10327 ASB5; ankyrin repeat and SOCS box protein 5"
					},
					{
						"name":"101911682 ASB6; ankyrin repeat and SOCS box containing 6\tK10328 ASB6; ankyrin repeat and SOCS box protein 6"
					},
					{
						"name":"101915702 ASB7; ankyrin repeat and SOCS box containing 7\tK10329 ASB7; ankyrin repeat and SOCS box protein 7"
					},
					{
						"name":"101916741 ASB9; ankyrin repeat and SOCS box protein 9\tK10331 ASB9; ankyrin repeat and SOCS box protein 9"
					},
					{
						"name":"101912136 ASB10; ankyrin repeat and SOCS box containing 10\tK10332 ASB10; ankyrin repeat and SOCS box protein 10"
					},
					{
						"name":"101912260 ASB11; ankyrin repeat and SOCS box containing 11\tK10333 ASB11; ankyrin repeat and SOCS box protein 11"
					},
					{
						"name":"101911212 ASB12; ankyrin repeat and SOCS box containing 12\tK10334 ASB12; ankyrin repeat and SOCS box protein 12"
					},
					{
						"name":"101911749 ASB13; ankyrin repeat and SOCS box containing 13\tK10335 ASB13; ankyrin repeat and SOCS box protein 13"
					},
					{
						"name":"101915478 ASB14; ankyrin repeat and SOCS box containing 14\tK10336 ASB14; ankyrin repeat and SOCS box protein 14"
					},
					{
						"name":"101918426 ASB15; ankyrin repeat and SOCS box containing 15\tK10337 ASB15; ankyrin repeat and SOCS box protein 15"
					},
					{
						"name":"101914002 ASB16; ankyrin repeat and SOCS box containing 16\tK10338 ASB16; ankyrin repeat and SOCS box protein 16"
					},
					{
						"name":"101912712 ASB18; ankyrin repeat and SOCS box containing 18\tK10340 ASB18; ankyrin repeat and SOCS box protein 18"
					},
					{
						"name":"101921381 WSB1; WD repeat and SOCS box containing 1\tK10341 WSB1; WD repeat and SOCS box-containing protein 1"
					},
					{
						"name":"101923868 WSB2; WD repeat and SOCS box containing 2\tK10342 WSB2; WD repeat and SOCS box-containing protein 2"
					},
					{
						"name":"101919367 SPSB1; splA\/ryanodine receptor domain and SOCS box containing 1\tK10343 SPSB1_4; SPRY domain-containing SOCS box protein 1\/4"
					},
					{
						"name":"101922582 SPSB4; splA\/ryanodine receptor domain and SOCS box containing 4\tK10343 SPSB1_4; SPRY domain-containing SOCS box protein 1\/4"
					},
					{
						"name":"101913681 SPSB3; splA\/ryanodine receptor domain and SOCS box containing 3\tK10345 SPSB3; SPRY domain-containing SOCS box protein 3"
					},
					{
						"name":"101912261 RAB40B; RAB40B, member RAS oncogene family\tK07928 RAB40; Ras-related protein Rab-40"
					},
					{
						"name":"101918877 RAB40C; RAB40C, member RAS oncogene family\tK07928 RAB40; Ras-related protein Rab-40"
					},
					{
						"name":"101912568 LRRC41; leucine rich repeat containing 41\tK10347 LRRC41; leucine-rich repeat-containing protein 41"
					},
					{
						"name":"101921773 RSPRY1; ring finger and SPRY domain containing 1\tK23332 RSPRY1; RING finger and SPRY domain-containing protein 1"
					},
					{
						"name":"101917779 ankyrin repeat domain-containing protein 9-like\tK25208 ANKRD9; ankyrin repeat domain-containing protein 9"
					},
					{
						"name":"101918009 ANKRD9; ankyrin repeat domain 9\tK25208 ANKRD9; ankyrin repeat domain-containing protein 9"
					},
					{
						"name":"101911496 KLHDC1; kelch domain containing 1\tK25810 KLHDC1; kelch domain-containing protein 1"
					}
					]
				}
				]
			},
			{
				"name":"Cul7 complex",
				"children":[
				{
					"name":"Ring finger protein",
					"children":[
					{
						"name":"101916874 RBX1; ring-box 1\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
					}
					]
				},
				{
					"name":"Cullin"
				},
				{
					"name":"Adaptor protein",
					"children":[
					{
						"name":"101911889 SKP1; S-phase kinase associated protein 1\tK03094 SKP1; S-phase kinase-associated protein 1"
					}
					]
				},
				{
					"name":"Target recognizing subunit",
					"children":[
					{
						"name":"101924554 FBXW8; F-box and WD repeat domain containing 8\tK10264 FBXW8; F-box and WD-40 domain protein 8"
					}
					]
				}
				]
			},
			{
				"name":"Cul8 complex",
				"children":[
				{
					"name":"Ring finger protein",
					"children":[
					{
						"name":"101916874 RBX1; ring-box 1\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
					}
					]
				},
				{
					"name":"Cullin"
				},
				{
					"name":"Adaptor protein"
				},
				{
					"name":"Target recognizing subunit"
				}
				]
			},
			{
				"name":"Cul9 complex",
				"children":[
				{
					"name":"Ring finger protein",
					"children":[
					{
						"name":"101916874 RBX1; ring-box 1\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
					}
					]
				},
				{
					"name":"Cullin",
					"children":[
					{
						"name":"101919102 CUL9; cullin-9\tK11970 CUL9; cullin 9"
					}
					]
				}
				]
			},
			{
				"name":"APC\/C",
				"children":[
				{
					"name":"Ring finger protein"
				},
				{
					"name":"Cullin",
					"children":[
					{
						"name":"101923964 ANAPC2; anaphase promoting complex subunit 2\tK03349 APC2; anaphase-promoting complex subunit 2"
					}
					]
				},
				{
					"name":"Target recognizing subunit",
					"children":[
					{
						"name":"101918465 CDC20; cell division cycle 20\tK03363 CDC20; cell division cycle 20, cofactor of APC complex"
					},
					{
						"name":"101919381 FZR1; fizzy\/cell division cycle 20 related 1\tK03364 CDH1; cell division cycle 20-like protein 1, cofactor of APC complex"
					}
					]
				},
				{
					"name":"Other subunits",
					"children":[
					{
						"name":"101916015 ANAPC1; anaphase promoting complex subunit 1\tK03348 APC1; anaphase-promoting complex subunit 1"
					},
					{
						"name":"101923640 CDC27; cell division cycle 27\tK03350 APC3; anaphase-promoting complex subunit 3"
					},
					{
						"name":"101916322 ANAPC4; anaphase promoting complex subunit 4\tK03351 APC4; anaphase-promoting complex subunit 4"
					},
					{
						"name":"101912746 ANAPC5; anaphase promoting complex subunit 5\tK03352 APC5; anaphase-promoting complex subunit 5"
					},
					{
						"name":"101912775 CDC16; cell division cycle 16\tK03353 APC6; anaphase-promoting complex subunit 6"
					},
					{
						"name":"101913263 ANAPC7; anaphase promoting complex subunit 7\tK03354 APC7; anaphase-promoting complex subunit 7"
					},
					{
						"name":"101921931 CDC23; cell division cycle 23\tK03355 APC8; anaphase-promoting complex subunit 8"
					},
					{
						"name":"101920027 ANAPC10; anaphase promoting complex subunit 10\tK03357 APC10; anaphase-promoting complex subunit 10"
					},
					{
						"name":"101916782 ANAPC13; anaphase promoting complex subunit 13\tK12456 APC13; anaphase-promoting complex subunit 13"
					},
					{
						"name":"101912834 ANAPC15; anaphase promoting complex subunit 15\tK25228 APC15; anaphase-promoting complex subunit 15"
					},
					{
						"name":"101916868 ANAPC16; anaphase promoting complex subunit 16\tK25229 APC16; anaphase-promoting complex subunit 16"
					}
					]
				}
				]
			},
			{
				"name":"BRCC complex",
				"children":[
				{
					"name":"106112589 BRCA1; BRCA1, DNA repair associated\tK10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]"
				},
				{
					"name":"101912402 BRCA2; BRCA2, DNA repair associated\tK08775 BRCA2; breast cancer 2 susceptibility protein"
				},
				{
					"name":"101916260 BRCC3; BRCA1\/BRCA2-containing complex subunit 3\tK11864 BRCC3; BRCA1\/BRCA2-containing complex subunit 3 [EC:3.4.19.-]"
				},
				{
					"name":"101910960 BARD1; BRCA1 associated RING domain 1\tK10683 BARD1; BRCA1-associated RING domain protein 1"
				},
				{
					"name":"101916479 BRE; brain and reproductive organ-expressed (TNFRSF1A modulator)\tK12173 BRE; BRCA1-A complex subunit BRE"
				},
				{
					"name":"101922449 RAD51; RAD51 recombinase\tK04482 RAD51; DNA repair protein RAD51"
				}
				]
			},
			{
				"name":"KPC complex",
				"children":[
				{
					"name":"101916231 RNF123; ring finger protein 123\tK12169 KPC1; Kip1 ubiquitination-promoting complex protein 1 [EC:2.3.2.27]"
				},
				{
					"name":"101911084 UBAC1; UBA domain containing 1\tK12174 KPC2; Kip1 ubiquitination-promoting complex protein 2"
				}
				]
			},
			{
				"name":"LUBAC complex",
				"children":[
				{
					"name":"101917453 SHARPIN; SHANK associated RH domain interactor\tK10630 RBCK1; RanBP-type and C3HC4-type zinc finger-containing protein 1 [EC:2.3.2.31]"
				}
				]
			},
			{
				"name":"CTLH complex",
				"children":[
				{
					"name":"101918369 RMND5A; required for meiotic nuclear division 5 homolog A\tK23333 RMND5; E3 ubiquitin-protein transferase RMND5 [EC:2.3.2.27]"
				},
				{
					"name":"101913519 RANBP10; RAN binding protein 10\tK23334 RANBP9_10; Ran-binding protein 9\/10"
				},
				{
					"name":"101916300 RANBP9; RAN binding protein 9\tK23334 RANBP9_10; Ran-binding protein 9\/10"
				},
				{
					"name":"101916103 ARMC8; armadillo repeat containing 8\tK23336 ARMC8; armadillo repeat-containing protein 8"
				},
				{
					"name":"101919289 MKLN1; muskelin 1\tK23337 MKLN1; muskelin"
				},
				{
					"name":"101916840 MAEA; macrophage erythroblast attacher\tK18624 MAEA; macrophage erythroblast attacher"
				},
				{
					"name":"101920571 GID4; GID complex subunit 4 homolog\tK23335 GID4; glucose-induced degradation protein 4"
				},
				{
					"name":"101918352 GID8; GID complex subunit 8 homolog\tK23338 GID8; glucose-induced degradation protein 8"
				},
				{
					"name":"101917954 YPEL5; yippee like 5\tK23339 YPEL5; protein yippee-like 5"
				},
				{
					"name":"101915641 WDR26; WD repeat domain 26\tK22382 WDR26; WD repeat-containing protein 26"
				}
				]
			},
			{
				"name":"ERAD complex",
				"children":[
				{
					"name":"101910285 AMFR; autocrine motility factor receptor\tK10636 AMFR; E3 ubiquitin-protein ligase AMFR [EC:2.3.2.36]"
				},
				{
					"name":"101913007 TMUB1; transmembrane and ubiquitin like domain containing 1\tK23340 TMUB; transmembrane and ubiquitin-like domain-containing protein"
				},
				{
					"name":"101913834 TMUB2; transmembrane and ubiquitin like domain containing 2\tK23340 TMUB; transmembrane and ubiquitin-like domain-containing protein"
				},
				{
					"name":"101911122 ERLIN1; erlin-1\tK23341 ERLIN; erlin"
				},
				{
					"name":"101913079 ERLIN2; ER lipid raft associated 2\tK23341 ERLIN; erlin"
				}
				]
			},
			{
				"name":"LMBR1L-GP78-UBAC2 complex",
				"children":[
				{
					"name":"101916869 LMBR1L; limb development membrane protein 1 like\tK25215 LMBR1L; protein LMBR1L"
				},
				{
					"name":"101910285 AMFR; autocrine motility factor receptor\tK10636 AMFR; E3 ubiquitin-protein ligase AMFR [EC:2.3.2.36]"
				},
				{
					"name":"101913748 UBAC2; UBA domain containing 2\tK25216 UBAC2; ubiquitin-associated domain-containing protein 2"
				}
				]
			},
			{
				"name":"STUB1-CHIC2  complex",
				"children":[
				{
					"name":"101921639 STUB1; STIP1 homology and U-box containing protein 1\tK09561 STUB1; STIP1 homology and U-box containing protein 1 [EC:2.3.2.27]"
				},
				{
					"name":"101921102 CHIC2; cysteine rich hydrophobic domain 2\tK28185 CHIC2; cysteine-rich hydrophobic domain-containing protein 2"
				}
				]
			},
			{
				"name":"SLX5-SLX8 complex"
			},
			{
				"name":"Multi subunit type E3 associated proteins",
				"children":[
				{
					"name":"101924966 CAND1; cullin associated and neddylation dissociated 1\tK17263 CAND1; cullin-associated NEDD8-dissociated protein 1"
				},
				{
					"name":"101918000 cullin-associated NEDD8-dissociated protein 1-like\tK24172 CAND2; cullin-associated NEDD8-dissociated protein 2"
				},
				{
					"name":"101911202 COMMD1; copper metabolism domain containing 1\tK22557 COMMD1; COMM domain containing 1"
				},
				{
					"name":"101912376 COMMD2; COMM domain containing 2\tK22558 COMMD2; COMM domain containing 2"
				},
				{
					"name":"106112273 COMMD3; COMM domain containing 3\tK22559 COMMD3; COMM domain containing 3"
				},
				{
					"name":"101911472 COMM domain-containing protein 5-like\tK22561 COMMD5; COMM domain containing 5"
				},
				{
					"name":"101919185 COMMD6; COMM domain containing 6\tK22562 COMMD6; COMM domain containing 6"
				},
				{
					"name":"101923418 COMMD7; COMM domain containing 7\tK22563 COMMD7; COMM domain containing 7"
				},
				{
					"name":"101923342 COMMD8; COMM domain containing 8\tK22564 COMMD8; COMM domain containing 8"
				},
				{
					"name":"101915120 COMMD9; COMM domain containing 9\tK22565 COMMD9; COMM domain containing 9"
				},
				{
					"name":"101913830 COMMD10; COMM domain containing 10\tK22566 COMMD10; COMM domain containing 10"
				},
				{
					"name":"101913129 DDRGK1; DDRGK domain containing 1\tK23344 DDRGK1; DDRGK domain-containing protein 1"
				},
				{
					"name":"101917107 GLMN; glomulin, FKBP associated protein\tK23345 GLMN; glomulin"
				},
				{
					"name":"101922171 IVNS1ABP; influenza virus NS1A binding protein\tK15046 IVNS1ABP; influenza virus NS1A-binding protein"
				},
				{
					"name":"101914536 UBXN7; UBX domain protein 7\tK24350 UBXN7; UBX domain-containing protein 7"
				},
				{
					"name":"101920335 PACRG; PARK2 coregulated\tK26163 PACRG; parkin coregulated gene protein"
				},
				{
					"name":"101919592 UBAP2L; ubiquitin associated protein 2 like\tK26545 UBAP2; ubiquitin-associated protein 2"
				},
				{
					"name":"101924847 UBAP2; ubiquitin associated protein 2\tK26545 UBAP2; ubiquitin-associated protein 2"
				},
				{
					"name":"101925006 UEVLD; UEV and lactate\/malate dehyrogenase domains\tK28518 UEVLD; ubiquitin-conjugating enzyme E2 variant 3"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Deubiquitinating enzyme (DUB)",
		"children":[
		{
			"name":"Ubiquitin-specific proteases (UBPs)",
			"children":[
			{
				"name":"UCH",
				"children":[
				{
					"name":"101924718 UCHL1; ubiquitin C-terminal hydrolase L1\tK05611 UCHL1; ubiquitin carboxyl-terminal hydrolase L1 [EC:3.4.19.12]"
				},
				{
					"name":"101921900 BAP1; BRCA1 associated protein 1\tK08588 BAP1; ubiquitin carboxyl-terminal hydrolase BAP1 [EC:3.4.19.12]"
				},
				{
					"name":"101916749 UCHL3; ubiquitin C-terminal hydrolase L3\tK05609 UCHL3; ubiquitin carboxyl-terminal hydrolase L3 [EC:3.4.19.12]"
				},
				{
					"name":"101918204 UCHL5; ubiquitin C-terminal hydrolase L5\tK05610 UCHL5; ubiquitin carboxyl-terminal hydrolase L5 [EC:3.4.19.12]"
				}
				]
			},
			{
				"name":"UBP\/USP",
				"children":[
				{
					"name":"101912553 CYLD; CYLD lysine 63 deubiquitinase\tK08601 CYLD; ubiquitin carboxyl-terminal hydrolase CYLD [EC:3.4.19.12]"
				},
				{
					"name":"101918460 ubiquitin carboxyl-terminal hydrolase CYLD-like\tK08601 CYLD; ubiquitin carboxyl-terminal hydrolase CYLD [EC:3.4.19.12]"
				},
				{
					"name":"101920556 USP1; ubiquitin specific peptidase 1\tK11832 USP1; ubiquitin carboxyl-terminal hydrolase 1 [EC:3.4.19.12]"
				},
				{
					"name":"101917313 USP2; ubiquitin specific peptidase 2\tK11833 USP2; ubiquitin carboxyl-terminal hydrolase 2 [EC:3.4.19.12]"
				},
				{
					"name":"101923077 USP3; ubiquitin specific peptidase 3\tK11986 USP3; ubiquitin carboxyl-terminal hydrolase 3 [EC:3.4.19.12]"
				},
				{
					"name":"101912095 ubiquitin carboxyl-terminal hydrolase 4-like\tK11835 USP4_11; ubiquitin carboxyl-terminal hydrolase 4\/11 [EC:3.4.19.12]"
				},
				{
					"name":"101913362 USP13; ubiquitin specific peptidase 13 (isopeptidase T-3)\tK11836 USP5_13; ubiquitin carboxyl-terminal hydrolase 5\/13 [EC:3.4.19.12]"
				},
				{
					"name":"101913660 USP5; ubiquitin specific peptidase 5\tK11836 USP5_13; ubiquitin carboxyl-terminal hydrolase 5\/13 [EC:3.4.19.12]"
				},
				{
					"name":"101919133 USP32; ubiquitin specific peptidase 32\tK11837 USP6_32; ubiquitin carboxyl-terminal hydrolase 6\/32 [EC:3.4.19.12]"
				},
				{
					"name":"101912182 USP7; ubiquitin specific peptidase 7\tK11838 USP7; ubiquitin carboxyl-terminal hydrolase 7 [EC:3.4.19.12]"
				},
				{
					"name":"101923369 USP8; ubiquitin specific peptidase 8\tK11839 USP8; ubiquitin carboxyl-terminal hydrolase 8 [EC:3.4.19.12]"
				},
				{
					"name":"101916746 USP24; ubiquitin specific peptidase 24\tK11840 USP9_24; ubiquitin carboxyl-terminal hydrolase 9\/24 [EC:3.4.19.12]"
				},
				{
					"name":"101921502 USP9X; ubiquitin specific peptidase 9, X-linked\tK11840 USP9_24; ubiquitin carboxyl-terminal hydrolase 9\/24 [EC:3.4.19.12]"
				},
				{
					"name":"101914671 USP10; ubiquitin specific peptidase 10\tK11841 USP10; ubiquitin carboxyl-terminal hydrolase 10 [EC:3.4.19.12]"
				},
				{
					"name":"101910462 USP12; ubiquitin specific peptidase 12\tK11842 USP12_46; ubiquitin carboxyl-terminal hydrolase 12\/46 [EC:3.4.19.12]"
				},
				{
					"name":"101912621 ubiquitin carboxyl-terminal hydrolase 12-like\tK11842 USP12_46; ubiquitin carboxyl-terminal hydrolase 12\/46 [EC:3.4.19.12]"
				},
				{
					"name":"101914043 USP46; ubiquitin specific peptidase 46\tK11842 USP12_46; ubiquitin carboxyl-terminal hydrolase 12\/46 [EC:3.4.19.12]"
				},
				{
					"name":"101916727 USP14; ubiquitin specific peptidase 14\tK11843 USP14; ubiquitin carboxyl-terminal hydrolase 14 [EC:3.4.19.12]"
				},
				{
					"name":"101912406 USP15; ubiquitin specific peptidase 15\tK21343 USP15; ubiquitin carboxyl-terminal hydrolase 15 [EC:3.4.19.12]"
				},
				{
					"name":"101915166 USP16; ubiquitin specific peptidase 16\tK11844 USP16_45; ubiquitin carboxyl-terminal hydrolase 16\/45 [EC:3.4.19.12]"
				},
				{
					"name":"101915569 USP45; ubiquitin specific peptidase 45\tK11844 USP16_45; ubiquitin carboxyl-terminal hydrolase 16\/45 [EC:3.4.19.12]"
				},
				{
					"name":"101915035 USP18; ubiquitin specific peptidase 18\tK11846 USP18_41; ubiquitin carboxyl-terminal hydrolase 18\/41 [EC:3.4.19.12]"
				},
				{
					"name":"101911607 USP19; ubiquitin specific peptidase 19\tK11847 USP19; ubiquitin carboxyl-terminal hydrolase 19 [EC:3.4.19.12]"
				},
				{
					"name":"101912495 USP20; ubiquitin specific peptidase 20\tK11848 USP20_33; ubiquitin carboxyl-terminal hydrolase 20\/33 [EC:3.4.19.12]"
				},
				{
					"name":"101919663 USP33; ubiquitin specific peptidase 33\tK11848 USP20_33; ubiquitin carboxyl-terminal hydrolase 20\/33 [EC:3.4.19.12]"
				},
				{
					"name":"101910609 PPOX; uncharacterized LOC101910609\tK21634 USP21; ubiquitin carboxyl-terminal hydrolase 21 [EC:3.4.19.12]"
				},
				{
					"name":"101914546 USP22; ubiquitin specific peptidase 22\tK11366 USP22_27_51; ubiquitin carboxyl-terminal hydrolase 22\/27\/51 [EC:3.4.19.12]"
				},
				{
					"name":"101923380 USP25; ubiquitin specific peptidase 25\tK11849 USP25; ubiquitin carboxyl-terminal hydrolase 25 [EC:3.4.19.12]"
				},
				{
					"name":"101920528 ubiquitin carboxyl-terminal hydrolase 37\tK11850 USP26_29_37; ubiquitin carboxyl-terminal hydrolase 26\/29\/37 [EC:3.4.19.12]"
				},
				{
					"name":"101913273 USP28; ubiquitin specific peptidase 28\tK21122 USP28; ubiquitin carboxyl-terminal hydrolase 28 [EC:3.4.19.12]"
				},
				{
					"name":"101913430 USP30; ubiquitin specific peptidase 30\tK11851 USP30; ubiquitin carboxyl-terminal hydrolase 30 [EC:3.4.19.12]"
				},
				{
					"name":"101922159 USP31; ubiquitin specific peptidase 31\tK11852 USP31; ubiquitin carboxyl-terminal hydrolase 31 [EC:3.4.19.12]"
				},
				{
					"name":"101921682 USP34; ubiquitin specific peptidase 34\tK11853 USP34; ubiquitin carboxyl-terminal hydrolase 34 [EC:3.4.19.12]"
				},
				{
					"name":"101920984 USP35; ubiquitin specific peptidase 35\tK11854 USP35_38; ubiquitin carboxyl-terminal hydrolase 35\/38 [EC:3.4.19.12]"
				},
				{
					"name":"101921594 USP38; ubiquitin specific peptidase 38\tK11854 USP35_38; ubiquitin carboxyl-terminal hydrolase 35\/38 [EC:3.4.19.12]"
				},
				{
					"name":"101912776 USP42; ubiquitin specific peptidase 42\tK11855 USP36_42; ubiquitin carboxyl-terminal hydrolase 36\/42 [EC:3.4.19.12]"
				},
				{
					"name":"101917777 USP36; ubiquitin specific peptidase 36\tK11855 USP36_42; ubiquitin carboxyl-terminal hydrolase 36\/42 [EC:3.4.19.12]"
				},
				{
					"name":"101913742 USP40; ubiquitin specific peptidase 40\tK11869 USP40; ubiquitin carboxyl-terminal hydrolase 40 [EC:3.4.19.12]"
				},
				{
					"name":"101919717 USP43; ubiquitin specific peptidase 43\tK11856 USP43; ubiquitin carboxyl-terminal hydrolase 43 [EC:3.4.19.12]"
				},
				{
					"name":"101910489 USP44; ubiquitin specific peptidase 44\tK11834 USP44_49; ubiquitin carboxyl-terminal hydrolase 44\/49 [EC:3.4.19.12]"
				},
				{
					"name":"101913194 USP49; ubiquitin specific peptidase 49\tK11834 USP44_49; ubiquitin carboxyl-terminal hydrolase 44\/49 [EC:3.4.19.12]"
				},
				{
					"name":"101919863 USP47; ubiquitin specific peptidase 47\tK11857 USP47; ubiquitin carboxyl-terminal hydrolase 47 [EC:3.4.19.12]"
				},
				{
					"name":"101922543 USP48; ubiquitin specific peptidase 48\tK11858 USP48; ubiquitin carboxyl-terminal hydrolase 48 [EC:3.4.19.12]"
				},
				{
					"name":"101914035 USP54; ubiquitin specific peptidase 54\tK27920 USP54; ubiquitin carboxyl-terminal hydrolase 54 [EC:3.4.19.12]"
				}
				]
			},
			{
				"name":"OTU",
				"children":[
				{
					"name":"101915217 OTUB1; OTU deubiquitinase, ubiquitin aldehyde binding 1\tK09602 OTUB1; ubiquitin thioesterase protein OTUB1 [EC:3.4.19.12]"
				},
				{
					"name":"101916229 OTUD3; OTU deubiquitinase 3\tK13717 OTUD3; OTU domain-containing protein 3 [EC:3.4.19.12]"
				},
				{
					"name":"101916062 OTUD6B; OTU domain containing 6B\tK18342 OTUD6; OTU domain-containing protein 6 [EC:3.4.19.12]"
				},
				{
					"name":"101911018 OTUD7B; OTU deubiquitinase 7B\tK11860 OTUD7A_B; OTU domain-containing protein 7 [EC:3.4.19.12]"
				},
				{
					"name":"101913019 OTUD7A; OTU deubiquitinase 7A\tK11860 OTUD7A_B; OTU domain-containing protein 7 [EC:3.4.19.12]"
				},
				{
					"name":"101919141 OTULIN; OTU deubiquitinase with linear linkage specificity\tK18343 OTULIN; ubiquitin thioesterase otulin [EC:3.4.19.12]"
				},
				{
					"name":"101911730 TNFAIP3; TNF alpha induced protein 3\tK11859 TNFAIP3; tumor necrosis factor, alpha-induced protein 3 [EC:3.4.19.12]"
				},
				{
					"name":"101915801 VCPIP1; valosin containing protein interacting protein 1\tK11861 VCPIP1; deubiquitinating protein VCIP135 [EC:3.4.19.12]"
				},
				{
					"name":"101915724 ZRANB1; zinc finger RANBP2-type containing 1\tK11862 ZRANB1; ubiquitin thioesterase ZRANB1 [EC:3.4.19.12]"
				}
				]
			},
			{
				"name":"MJD",
				"children":[
				{
					"name":"101914069 ATXN3; ataxin 3\tK11863 ATXN3; ataxin-3 [EC:3.4.22.-]"
				},
				{
					"name":"101920162 JOSD1; Josephin domain containing 1\tK15235 JOSD; josephin [EC:3.4.19.12]"
				},
				{
					"name":"106112053 JOSD2; Josephin domain containing 2\tK15235 JOSD; josephin [EC:3.4.19.12]"
				}
				]
			},
			{
				"name":"MINDY",
				"children":[
				{
					"name":"101913365 FAM63B; family with sequence similarity 63 member B\tK01309 MINDY1_2; ubiquitin carboxyl-terminal hydrolase MINDY-1\/2 [EC:3.4.19.12]"
				},
				{
					"name":"101913080 protein FAM188B2\tK22647 MINDY3_4; ubiquitin carboxyl-terminal hydrolase MINDY-3\/4 [EC:3.4.19.12]"
				},
				{
					"name":"101920663 FAM188B; family with sequence similarity 188 member B\tK22647 MINDY3_4; ubiquitin carboxyl-terminal hydrolase MINDY-3\/4 [EC:3.4.19.12]"
				},
				{
					"name":"101921985 FAM188A; family with sequence similarity 188 member A\tK22647 MINDY3_4; ubiquitin carboxyl-terminal hydrolase MINDY-3\/4 [EC:3.4.19.12]"
				}
				]
			},
			{
				"name":"JAMM",
				"children":[
				{
					"name":"101916260 BRCC3; BRCA1\/BRCA2-containing complex subunit 3\tK11864 BRCC3; BRCA1\/BRCA2-containing complex subunit 3 [EC:3.4.19.-]"
				},
				{
					"name":"101922094 MYSM1; Myb like, SWIRM and MPN domains 1\tK11865 MYSM1; histone H2A deubiquitinase [EC:3.4.19.-]"
				},
				{
					"name":"101911066 MPND; MPN domain containing\tK24173 MPND; MPN domain-containing protein"
				},
				{
					"name":"101910343 PSMD14; proteasome 26S subunit, non-ATPase 14\tK03030 PSMD14; 26S proteasome regulatory subunit N11"
				},
				{
					"name":"101922348 STAMBP; STAM binding protein\tK11866 STAMBP; STAM-binding protein [EC:3.4.19.12]"
				},
				{
					"name":"101915103 STAMBPL1; STAM binding protein like 1\tK11867 STAMBPL1; AMSH-like protease [EC:3.4.19.12]"
				}
				]
			},
			{
				"name":"PPPDE",
				"children":[
				{
					"name":"101919987 DESI2; desumoylating isopeptidase 2\tK22763 DESI2; deubiquitinase DESI2 [EC:3.4.19.12]"
				},
				{
					"name":"106113003 desumoylating isopeptidase 2-like\tK22763 DESI2; deubiquitinase DESI2 [EC:3.4.19.12]"
				}
				]
			},
			{
				"name":"ZUFSP",
				"children":[
				{
					"name":"101919796 ZUFSP; zinc finger with UFM1 specific peptidase domain\tK24134 ZUP1; zinc finger-containing ubiquitin peptidase 1 [EC:3.4.19.12]"
				}
				]
			},
			{
				"name":"BRISC complex",
				"children":[
				{
					"name":"101916743 FAM175B; family with sequence similarity 175 member B\tK20799 FAM175B; BRISC complex subunit Abro1"
				},
				{
					"name":"101915184 BABAM1; BRISC and BRCA1 A complex member 1\tK20776 BABAM; BRISC and BRCA1-A complex member 1"
				},
				{
					"name":"101916260 BRCC3; BRCA1\/BRCA2-containing complex subunit 3\tK11864 BRCC3; BRCA1\/BRCA2-containing complex subunit 3 [EC:3.4.19.-]"
				},
				{
					"name":"101916479 BRE; brain and reproductive organ-expressed (TNFRSF1A modulator)\tK12173 BRE; BRCA1-A complex subunit BRE"
				}
				]
			}
			]
		},
		{
			"name":"UBL-specific proteases (ULPs)",
			"children":[
			{
				"name":"101919817 SENP1; SUMO1\/sentrin specific peptidase 1\tK08592 SENP1; sentrin-specific protease 1 [EC:3.4.22.68]"
			},
			{
				"name":"101925024 SENP2; SUMO1\/sentrin\/SMT3 specific peptidase 2\tK03345 SENP2; sentrin-specific protease 2 (axin associating molecule) [EC:3.4.22.68]"
			},
			{
				"name":"101914392 SENP5; SUMO1\/sentrin specific peptidase 5\tK08594 SENP5; sentrin-specific protease 5 [EC:3.4.22.68]"
			},
			{
				"name":"101920015 SENP6; SUMO1\/sentrin specific peptidase 6\tK08595 SENP6; sentrin-specific protease 6 [EC:3.4.22.68]"
			},
			{
				"name":"101913843 SENP7; SUMO1\/sentrin specific peptidase 7\tK08596 SENP7; sentrin-specific protease 7 [EC:3.4.22.68]"
			},
			{
				"name":"101922230 SENP8; SUMO\/sentrin peptidase family member, NEDD8 specific\tK08597 SENP8; sentrin-specific protease 8 [EC:3.4.22.68]"
			},
			{
				"name":"101916749 UCHL3; ubiquitin C-terminal hydrolase L3\tK05609 UCHL3; ubiquitin carboxyl-terminal hydrolase L3 [EC:3.4.19.12]"
			},
			{
				"name":"101923408 DESI1; desumoylating isopeptidase 1\tK22762 DESI1; desumoylating isopeptidase 1 [EC:3.4.-.-]"
			},
			{
				"name":"101919063 USPL1; ubiquitin specific peptidase like 1\tK23008 USPL1; SUMO-specific isopeptidase USPL1 [EC:3.4.22.-]"
			},
			{
				"name":"COP9 signalosome (CSN) complex",
				"children":[
				{
					"name":"101924914 GPS1; G protein pathway suppressor 1\tK12175 GPS1; COP9 signalosome complex subunit 1"
				},
				{
					"name":"101922207 COPS2; COP9 signalosome subunit 2\tK12176 COPS2; COP9 signalosome complex subunit 2"
				},
				{
					"name":"101914897 COPS3; COP9 signalosome subunit 3\tK12177 COPS3; COP9 signalosome complex subunit 3"
				},
				{
					"name":"101920216 COPS4; COP9 signalosome subunit 4\tK12178 COPS4; COP9 signalosome complex subunit 4"
				},
				{
					"name":"101913165 COPS5; COP9 signalosome subunit 5\tK09613 COPS5; COP9 signalosome complex subunit 5 [EC:3.4.-.-]"
				},
				{
					"name":"101918506 COPS7A; COP9 signalosome subunit 7A\tK12180 COPS7; COP9 signalosome complex subunit 7"
				},
				{
					"name":"101920365 COPS7B; COP9 signalosome subunit 7B\tK12180 COPS7; COP9 signalosome complex subunit 7"
				},
				{
					"name":"101923026 COPS8; COP9 signalosome subunit 8\tK12181 COPS8; COP9 signalosome complex subunit 8"
				},
				{
					"name":"106112145 COPS9; COP9 signalosome subunit 9\tK28062 COPS9; COP9 signalosome complex subunit 9"
				}
				]
			}
			]
		}
		]
	}
	]
}