{
	"name":"git02048",
	"children":[
	{
		"name":"CRISPR-Cas system",
		"children":[
		{
			"name":"Universal Cas proteins",
			"children":[
			{
				"name":"C6V83_06685 CRISPR-associated endonuclease Cas4\/Cas1\tK15342 cas1; CRISP-associated protein Cas1"
			},
			{
				"name":"C6V83_06690 cas2; CRISPR-associated endonuclease Cas2\tK09951 cas2; CRISPR-associated protein Cas2"
			}
			]
		},
		{
			"name":"Type I CRISPR-Cas system",
			"children":[
			{
				"name":"Type I signiture cas proteins",
				"children":[
				{
					"name":"C6V83_06675 cas3u; type I-U CRISPR-associated helicase\/endonuclease Cas3\tK07012 cas3; CRISPR-associated endonuclease\/helicase Cas3 [EC:3.1.-.- 5.6.2.4]"
				}
				]
			},
			{
				"name":"Subtype I-A factors"
			},
			{
				"name":"Subtype I-B factors"
			},
			{
				"name":"Subtype I-C factors"
			},
			{
				"name":"Subtype I-D factors"
			},
			{
				"name":"Subtype I-E factors"
			},
			{
				"name":"Subtype I-F factors"
			},
			{
				"name":"Subtype I-U factors",
				"children":[
				{
					"name":"C6V83_06665 cas7u; type I-U CRISPR-associated protein Cas7\tK19131 csb1; CRISPR-associated protein Csb1"
				},
				{
					"name":"C6V83_06670 cas5u6u; type I-U CRISPR-associated protein Cas5\/Cas6\tK19132 csb2; CRISPR-associated protein Csb2"
				},
				{
					"name":"C6V83_06680 CRISPR-associated protein\tK19133 csb3; CRISPR-associated protein Csb3"
				}
				]
			}
			]
		},
		{
			"name":"Type II CRISPR-Cas system",
			"children":[
			{
				"name":"Type II signiture cas proteins"
			},
			{
				"name":"Subtype II-A factors"
			},
			{
				"name":"Subtype II-B factors"
			}
			]
		},
		{
			"name":"Type III CRISPR-Cas system",
			"children":[
			{
				"name":"Type III signiture cas proteins"
			},
			{
				"name":"Subtype III-A factors"
			},
			{
				"name":"Subtype III-B factors"
			},
			{
				"name":"Subtype III-U factors"
			}
			]
		}
		]
	},
	{
		"name":"Restriction and modification system (R-M system)",
		"children":[
		{
			"name":"Type I R-M system",
			"children":[
			{
				"name":"C6V83_08260 DEAD\/DEAH box helicase\tK01153 hsdR; type I restriction enzyme, R subunit [EC:3.1.21.3]"
			},
			{
				"name":"C6V83_08240 restriction endonuclease subunit M\tK03427 hsdM; type I restriction enzyme M protein [EC:2.1.1.72]"
			}
			]
		},
		{
			"name":"Type II R-M system",
			"children":[
			{
				"name":"Restriction endonucleases"
			},
			{
				"name":"DNA methyltransferases",
				"children":[
				{
					"name":"C6V83_01330 hypothetical protein\tK07318 K07318; adenine-specific DNA-methyltransferase [EC:2.1.1.72]"
				},
				{
					"name":"C6V83_00110 DNA methyltransferase\tK00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]"
				},
				{
					"name":"C6V83_05735 DNA (cytosine-5-)-methyltransferase\tK00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]"
				}
				]
			}
			]
		},
		{
			"name":"Type III R-M system"
		},
		{
			"name":"Type IV R-M system",
			"children":[
			{
				"name":"C6V83_05725 HNH endonuclease\tK07451 mcrA; 5-methylcytosine-specific restriction enzyme A [EC:3.1.21.-]"
			},
			{
				"name":"C6V83_14965 hypothetical protein\tK07452 mcrB; 5-methylcytosine-specific restriction enzyme B [EC:3.1.21.-]"
			},
			{
				"name":"C6V83_14970 hypothetical protein\tK19147 mcrC; 5-methylcytosine-specific restriction enzyme subunit McrC"
			}
			]
		}
		]
	},
	{
		"name":"Toxin-antitoxin system (TA system)",
		"children":[
		{
			"name":"Type I TA system",
			"children":[
			{
				"name":"Hok-Sok"
			},
			{
				"name":"SymE-SymR"
			},
			{
				"name":"Ldr-Rdl"
			},
			{
				"name":"TisB-IstR"
			},
			{
				"name":"Ibs-Sib"
			},
			{
				"name":"ShoB-OhsC"
			},
			{
				"name":"RalR-RalA"
			}
			]
		},
		{
			"name":"Type II TA system",
			"children":[
			{
				"name":"MazF-MazE"
			},
			{
				"name":"ChpB-ChpS"
			},
			{
				"name":"YhaV-PrlF"
			},
			{
				"name":"RelE\/StbE-RelB\/StbD"
			},
			{
				"name":"YafQ-dinJ"
			},
			{
				"name":"YoeB-YefM"
			},
			{
				"name":"HipA-HipB"
			},
			{
				"name":"HicA-HicB"
			},
			{
				"name":"YafO-YafN"
			},
			{
				"name":"PspC-PspB"
			},
			{
				"name":"CcdB-CcdA"
			},
			{
				"name":"ParE-ParD"
			},
			{
				"name":"Doc-Phd"
			},
			{
				"name":"HigB-HigA"
			},
			{
				"name":"MqsR-MqsA"
			},
			{
				"name":"VapC-VapB",
				"children":[
				{
					"name":"C6V83_06700 VapC toxin family PIN domain ribonuclease\tK28141 vapC1S; ribonuclease VapC1\/3\/9\/12 [EC:3.1.-.-]"
				},
				{
					"name":"C6V83_07945 VapC toxin family PIN domain ribonuclease\tK28141 vapC1S; ribonuclease VapC1\/3\/9\/12 [EC:3.1.-.-]"
				},
				{
					"name":"C6V83_06695 hypothetical protein\tK28148 vapB2; antitoxin VapB2"
				},
				{
					"name":"C6V83_06725 hypothetical protein\tK28148 vapB2; antitoxin VapB2"
				},
				{
					"name":"C6V83_11610 VapC toxin family PIN domain ribonuclease\tK28149 vapC4_5_8; ribonuclease VapC4\/5\/8 [EC:3.1.-.-]"
				},
				{
					"name":"C6V83_11615 type II toxin-antitoxin system prevent-host-death family antitoxin\tK28150 vapB4_5; antitoxin VapB4\/5"
				},
				{
					"name":"C6V83_04370 VapC toxin family PIN domain ribonuclease\tK19686 vapC28S; ribonuclease VapC28\/30\/34\/36\/42 [EC:3.1.-.-]"
				},
				{
					"name":"C6V83_04375 hypothetical protein\tK19687 vapB28S; antitoxin VapB28\/30\/34\/36\/42"
				}
				]
			},
			{
				"name":"PezT-PezA"
			},
			{
				"name":"YobL-YobK"
			},
			{
				"name":"YokI-YokJ"
			},
			{
				"name":"YqcG-YqcF"
			},
			{
				"name":"YxiD-YxxD"
			},
			{
				"name":"FitB-FitA"
			},
			{
				"name":"BC_0920-BC_0921"
			},
			{
				"name":"SpoIISA-SpoIISB"
			},
			{
				"name":"Tse6-Tsi6"
			},
			{
				"name":"Type II TA system related factors",
				"children":[
				{
					"name":"C6V83_12740 cell division protein FtsZ\tK03531 ftsZ; cell division protein FtsZ"
				},
				{
					"name":"C6V83_02545 tRNA glutamyl-Q(34) synthetase GluQRS\tK01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]"
				},
				{
					"name":"C6V83_14160 glutamate--tRNA ligase\tK01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]"
				}
				]
			}
			]
		},
		{
			"name":"Type III TA system",
			"children":[
			{
				"name":"AbiQ system"
			}
			]
		},
		{
			"name":"Type IV TA system",
			"children":[
			{
				"name":"YeeV-YeeU"
			},
			{
				"name":"CptA-CptB"
			},
			{
				"name":"AbiEii-AbiEi"
			}
			]
		},
		{
			"name":"Type V TA system",
			"children":[
			{
				"name":"GhoT-GhoS"
			},
			{
				"name":"Other GhoT\/OrtT toxin family protein"
			}
			]
		},
		{
			"name":"Type VI TA system",
			"children":[
			{
				"name":"SocB-SocA"
			}
			]
		},
		{
			"name":"Type VII TA system",
			"children":[
			{
				"name":"Hha-TomB"
			},
			{
				"name":"TglT-TakA"
			},
			{
				"name":"HepT-MntA"
			}
			]
		},
		{
			"name":"Type VIII TA system",
			"children":[
			{
				"name":"SdsR-RyeA"
			}
			]
		}
		]
	},
	{
		"name":"DNA phosphothiolation system",
		"children":[
		{
			"name":"Sulfur modification proteins",
			"children":[
			{
				"name":"C6V83_14410 cysteine desulfurase NifS\tK04487 iscS; cysteine desulfurase [EC:2.8.1.7]"
			}
			]
		},
		{
			"name":"DNA phosphorothioation-dependent restriction proteins"
		}
		]
	}
	]
}