{ "name":"gmh03019", "children":[ { "name":"Eukaryotic type", "children":[ { "name":"mRNA processing factors", "children":[ { "name":"5' end processing", "children":[ { "name":"Capping factors", "children":[ { "name":"115535448 rnmt; (RefSeq) mRNA cap guanine-N7 methyltransferase\tK00565 RNMT; mRNA (guanine-N7-)-methyltransferase [EC:2.1.1.56]" }, { "name":"115534420 rngtt; (RefSeq) mRNA-capping enzyme\tK13917 RNGTT; mRNA-capping enzyme [EC:2.7.7.50 3.6.1.74]" }, { "name":"115545846 cdk7; (RefSeq) cyclin-dependent kinase 7 isoform X1\tK02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]" }, { "name":"115534401 cmtr1; (RefSeq) cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1\tK14589 CMTR1; cap1 methyltransferase [EC:2.1.1.57]" }, { "name":"115559109 cmtr2; (RefSeq) cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2\tK14590 CMTR2; cap2 methyltransferase [EC:2.1.1.296]" }, { "name":"115559131 ramac; (RefSeq) RNA guanine-N7 methyltransferase activating subunit\tK18708 FAM103A1; RNMT-activating mini protein" } ] }, { "name":"Cap binding complex", "children":[ { "name":"115552784 ncbp1; (RefSeq) nuclear cap-binding protein subunit 1\tK12882 NCBP1; nuclear cap-binding protein subunit 1" }, { "name":"115556382 ncbp2; (RefSeq) nuclear cap-binding protein subunit 2\tK12883 NCBP2; nuclear cap-binding protein subunit 2" } ] } ] }, { "name":"3' end processing", "children":[ { "name":"Pre-mRNA cleavage factor Im (CFIm)", "children":[ { "name":"115559108 nudt21; (RefSeq) cleavage and polyadenylation specificity factor subunit 5\tK14397 NUDT21; cleavage and polyadenylation specificity factor subunit 5" }, { "name":"115531959 cpsf6; (RefSeq) LOW QUALITY PROTEIN: cleavage and polyadenylation specificity factor subunit 6\tK14398 CPSF6_7; cleavage and polyadenylation specificity factor subunit 6\/7" }, { "name":"115558956 cleavage and polyadenylation specificity factor subunit 7-like isoform X1\tK14398 CPSF6_7; cleavage and polyadenylation specificity factor subunit 6\/7" } ] }, { "name":"Pre-mRNA cleavage factor IIm (CFIIm)", "children":[ { "name":"115552405 clp1; (RefSeq) polyribonucleotide 5'-hydroxyl-kinase Clp1\tK14399 CLP1; polyribonucleotide 5'-hydroxyl-kinase [EC:2.7.1.78]" }, { "name":"115546697 pcf11; (RefSeq) pre-mRNA cleavage complex 2 protein Pcf11\tK14400 PCF11; pre-mRNA cleavage complex 2 protein Pcf11" } ] }, { "name":"Cleavage and polyadenylation specificity factor (CPSF) complex", "children":[ { "name":"115535993 cpsf1; (RefSeq) cleavage and polyadenylation specificity factor subunit 1 isoform X1\tK14401 CPSF1; cleavage and polyadenylation specificity factor subunit 1" }, { "name":"115533943 cpsf2; (RefSeq) cleavage and polyadenylation specificity factor subunit 2\tK14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2" }, { "name":"115534519 cleavage and polyadenylation specificity factor subunit 3-like isoform X1\tK14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]" }, { "name":"115543655 cleavage and polyadenylation specificity factor subunit 3\tK14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]" }, { "name":"115540611 pre-mRNA 3'-end-processing factor FIP1-like isoform X1\tK14405 FIP1L1; pre-mRNA 3'-end-processing factor FIP1" }, { "name":"115555833 fip1l1; (RefSeq) pre-mRNA 3'-end-processing factor FIP1\tK14405 FIP1L1; pre-mRNA 3'-end-processing factor FIP1" }, { "name":"115548260 wdr33; (RefSeq) pre-mRNA 3' end processing protein WDR33 isoform X1\tK15542 PFS2; polyadenylation factor subunit 2" }, { "name":"115557015 wdr82; (RefSeq) WD repeat-containing protein 82\tK14962 WDR82; COMPASS component SWD2" }, { "name":"115529750 serine\/threonine-protein phosphatase PP1-beta catalytic subunit-like\tK06269 PPP1C; serine\/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]" }, { "name":"115530967 serine\/threonine-protein phosphatase PP1-gamma catalytic subunit B-like\tK06269 PPP1C; serine\/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]" }, { "name":"115533901 serine\/threonine-protein phosphatase PP1-beta catalytic subunit-like\tK06269 PPP1C; serine\/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]" }, { "name":"115537118 serine\/threonine-protein phosphatase alpha-2 isoform-like\tK06269 PPP1C; serine\/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]" }, { "name":"115543833 serine\/threonine-protein phosphatase PP1-beta catalytic subunit\tK06269 PPP1C; serine\/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]" }, { "name":"115545230 serine\/threonine-protein phosphatase PP1-gamma catalytic subunit\tK06269 PPP1C; serine\/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]" }, { "name":"115557461 ssu72; (RefSeq) RNA polymerase II subunit A C-terminal domain phosphatase SSU72 isoform X1\tK15544 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 [EC:3.1.3.16]" } ] }, { "name":"Cleavage stimulation factor (CSTF) complex", "children":[ { "name":"115556791 cstf1; (RefSeq) cleavage stimulation factor subunit 1\tK14406 CSTF1; cleavage stimulation factor subunit 1" }, { "name":"115552317 cstf2; (RefSeq) cleavage stimulation factor subunit 2 isoform X1\tK14407 CSTF2; cleavage stimulation factor subunit 2" }, { "name":"115558740 cstf3; (RefSeq) cleavage stimulation factor subunit 3\tK14408 CSTF3; cleavage stimulation factor subunit 3" }, { "name":"115533064 sympk; (RefSeq) symplekin\tK06100 SYMPK; symplekin" } ] }, { "name":"U7-dependent histone pre-mRNA processing factors", "children":[ { "name":"115557561 snrpb; (RefSeq) small nuclear ribonucleoprotein-associated proteins B and B'\tK11086 SNRPB; small nuclear ribonucleoprotein B and B'" }, { "name":"115542187 small nuclear ribonucleoprotein Sm D3\tK11088 SNRPD3; small nuclear ribonucleoprotein D3" }, { "name":"115542822 small nuclear ribonucleoprotein Sm D3\tK11088 SNRPD3; small nuclear ribonucleoprotein D3" }, { "name":"115540943 snrpe; (RefSeq) small nuclear ribonucleoprotein E\tK11097 SNRPE; small nuclear ribonucleoprotein E" }, { "name":"115541496 snrpf; (RefSeq) small nuclear ribonucleoprotein F\tK11098 SNRPF; small nuclear ribonucleoprotein F" }, { "name":"115548629 snrpg; (RefSeq) small nuclear ribonucleoprotein G\tK11099 SNRPG; small nuclear ribonucleoprotein G" }, { "name":"115536125 lsm10; (RefSeq) U7 snRNA-associated Sm-like protein LSm10\tK25591 LSM10; U7 snRNA-associated Sm-like protein LSm10" }, { "name":"115552879 lsm11; (RefSeq) U7 snRNA-associated Sm-like protein LSm11\tK25592 LSM11; U7 snRNA-associated Sm-like protein LSm11" }, { "name":"115533943 cpsf2; (RefSeq) cleavage and polyadenylation specificity factor subunit 2\tK14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2" }, { "name":"115534519 cleavage and polyadenylation specificity factor subunit 3-like isoform X1\tK14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]" }, { "name":"115543655 cleavage and polyadenylation specificity factor subunit 3\tK14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]" }, { "name":"115552317 cstf2; (RefSeq) cleavage stimulation factor subunit 2 isoform X1\tK14407 CSTF2; cleavage stimulation factor subunit 2" }, { "name":"115533064 sympk; (RefSeq) symplekin\tK06100 SYMPK; symplekin" }, { "name":"115546459 uncharacterized protein LOC115546459 isoform X1\tK18710 SLBP; histone RNA hairpin-binding protein" }, { "name":"115552232 slbp; (RefSeq) histone RNA hairpin-binding protein isoform X1\tK18710 SLBP; histone RNA hairpin-binding protein" } ] }, { "name":"DRB sensitivity inducing factor (DSIF) complex", "children":[ { "name":"115547749 supt4h1; (RefSeq) transcription elongation factor SPT4\tK15171 SUPT4H1; transcription elongation factor SPT4" }, { "name":"115528832 supt5h; (RefSeq) transcription elongation factor SPT5 isoform X1\tK15172 SUPT5H; transcription elongation factor SPT5" } ] }, { "name":"N6-methyltransferase complex", "children":[ { "name":"115529091 mettl3; (RefSeq) LOW QUALITY PROTEIN: N6-adenosine-methyltransferase catalytic subunit\tK05925 METTL3; mRNA m6A methyltransferase catalytic subunit [EC:2.1.1.348]" }, { "name":"115540596 mettl14; (RefSeq) N6-adenosine-methyltransferase non-catalytic subunit\tK23960 METTL14; mRNA m6A methyltransferase non-catalytic subunit" }, { "name":"115537124 mettl4; (RefSeq) methyltransferase-like protein 4 isoform X1\tK24174 METTL4; N(6)-adenine-specific DNA methyltransferase [EC:2.1.1.72]" }, { "name":"115561283 mettl16; (RefSeq) RNA N6-adenosine-methyltransferase METTL16\tK11393 METTL16; U6 snRNA m6A methyltransferase [EC:2.1.1.346]" }, { "name":"115534154 wtap; (RefSeq) pre-mRNA-splicing regulator WTAP\tK22824 WTAP; pre-mRNA-splicing regulator WTAP" }, { "name":"115553703 virma; (RefSeq) protein virilizer homolog isoform X1\tK22910 VIRMA; protein virilizer" }, { "name":"115542801 rbm15; (RefSeq) LOW QUALITY PROTEIN: RNA-binding protein 15\tK13190 RBM15; RNA-binding protein 15" }, { "name":"115556918 rbm15b; (RefSeq) putative RNA-binding protein 15B\tK13190 RBM15; RNA-binding protein 15" }, { "name":"115542848 E3 ubiquitin-protein ligase Hakai-like isoform X1\tK15685 CBLL1; E3 ubiquitin-protein ligase Hakai [EC:2.3.2.27]" } ] }, { "name":"Poly(A) addition factors", "children":[ { "name":"115534381 poly(A) polymerase type 3-like\tK14376 PAP; poly(A) polymerase [EC:2.7.7.19]" }, { "name":"115559587 papolg; (RefSeq) poly(A) polymerase gamma isoform X1\tK14376 PAP; poly(A) polymerase [EC:2.7.7.19]" }, { "name":"115545575 tent2; (RefSeq) poly(A) RNA polymerase GLD2 isoform X1\tK14079 PAPD4; poly(A) RNA polymerase GLD2 [EC:2.7.7.19]" }, { "name":"115531455 tut1; (RefSeq) speckle targeted PIP5K1A-regulated poly(A) polymerase\tK18709 TUT1; speckle targeted PIP5K1A-regulated poly(A) polymerase [EC:2.7.7.19 2.7.7.52]" } ] }, { "name":"Negative regulators of mRNA 3' end processing", "children":[ { "name":"115533179 bard1; (RefSeq) BRCA1-associated RING domain protein 1 isoform X1\tK10683 BARD1; BRCA1-associated RING domain protein 1" }, { "name":"115558812 rbm26; (RefSeq) RNA-binding protein 26\tK13192 RBM26; RNA-binding protein 26" }, { "name":"115558799 fto; (RefSeq) alpha-ketoglutarate-dependent dioxygenase FTO isoform X1\tK19469 FTO; mRNA N6-methyladenine demethylase [EC:1.14.11.53]" }, { "name":"115540507 alkbh5; (RefSeq) RNA demethylase ALKBH5\tK10767 ALKBH5; mRNA N6-methyladenine demethylase [EC:1.14.11.53]" }, { "name":"115545430 tardbp; (RefSeq) TAR DNA-binding protein 43 isoform X1\tK23600 TARDBP; TAR DNA-binding protein 43" }, { "name":"115557602 TAR DNA-binding protein 43-like\tK23600 TARDBP; TAR DNA-binding protein 43" } ] } ] }, { "name":"Other processing factors", "children":[ { "name":"115560827 dhx40; (RefSeq) probable ATP-dependent RNA helicase DHX40\tK18711 DHX40; ATP-dependent RNA helicase DHX40 [EC:5.6.2.6]" }, { "name":"115532034 kin; (RefSeq) DNA\/RNA-binding protein KIN17\tK13102 KIN; DNA\/RNA-binding protein KIN17" }, { "name":"115532824 mettl8; (RefSeq) methyltransferase-like protein 8 isoform X1\tK24975 METTL8; mRNA N(3)-methylcytidine methyltransferase METTL8 [EC:2.1.1.-]" }, { "name":"115534040 mettl22; (RefSeq) methyltransferase-like protein 22\tK23040 METTL22; methyltransferase-like protein 22 [EC:2.1.1.-]" }, { "name":"115534605 terminal nucleotidyltransferase 5A-like\tK23033 TENT5A_B; terminal nucleotidyltransferase 5A\/B [EC:2.7.7.-]" }, { "name":"115544973 tent5b; (RefSeq) terminal nucleotidyltransferase 5B\tK23033 TENT5A_B; terminal nucleotidyltransferase 5A\/B [EC:2.7.7.-]" }, { "name":"115553570 terminal nucleotidyltransferase 5A-like\tK23033 TENT5A_B; terminal nucleotidyltransferase 5A\/B [EC:2.7.7.-]" }, { "name":"115533255 tent5c; (RefSeq) terminal nucleotidyltransferase 5C\tK23034 TENT5C; terminal nucleotidyltransferase 5C [EC:2.7.7.19]" }, { "name":"115552781 tent5d; (RefSeq) terminal nucleotidyltransferase 5D\tK23035 TENT5D; terminal nucleotidyltransferase 5D [EC:2.7.7.19]" }, { "name":"115534161 zc3h14; (RefSeq) zinc finger CCCH domain-containing protein 14 isoform X1\tK23038 ZC3H14; zinc finger CCCH domain-containing protein 14" }, { "name":"115529604 serrate RNA effector molecule homolog isoform X1\tK27103 SRRT; serrate RNA effector molecule" }, { "name":"115546889 srrt; (RefSeq) serrate RNA effector molecule homolog\tK27103 SRRT; serrate RNA effector molecule" } ] } ] }, { "name":"mRNA surveillance and transport factors", "children":[ { "name":"Transport factors", "children":[ { "name":"EJC complex", "children":[ { "name":"115553592 rbm8a; (RefSeq) RNA-binding protein 8A isoform X1\tK12876 RBM8A; RNA-binding protein 8A" }, { "name":"115555432 magoh; (RefSeq) protein mago nashi homolog\tK12877 MAGOH; protein mago nashi" }, { "name":"115529505 THO complex subunit 4-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"115540441 THO complex subunit 4-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"115539941 eif4a3; (RefSeq) eukaryotic initiation factor 4A-III\tK13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7]" }, { "name":"115557577 ccdc174; (RefSeq) coiled-coil domain-containing protein 174\tK25178 CCDC174; coiled-coil domain-containing protein 174" }, { "name":"115534738 casc3; (RefSeq) protein CASC3 isoform X1\tK14323 CASC3; protein CASC3" }, { "name":"115533167 sap18; (RefSeq) histone deacetylase complex subunit SAP18\tK14324 SAP18; histone deacetylase complex subunit SAP18" }, { "name":"115547837 histone deacetylase complex subunit SAP18-like\tK14324 SAP18; histone deacetylase complex subunit SAP18" }, { "name":"115543538 pnn; (RefSeq) LOW QUALITY PROTEIN: pinin\tK13114 PNN; pinin" }, { "name":"115549165 apoptotic chromatin condensation inducer in the nucleus-like isoform X1\tK12875 ACIN1; apoptotic chromatin condensation inducer in the nucleus" }, { "name":"115531357 rnps1; (RefSeq) LOW QUALITY PROTEIN: RNA-binding protein with serine-rich domain 1\tK14325 RNPS1; RNA-binding protein with serine-rich domain 1" }, { "name":"115544353 srrm1; (RefSeq) serine\/arginine repetitive matrix protein 1 isoform X1\tK13171 SRRM1; serine\/arginine repetitive matrix protein 1" } ] }, { "name":"TREX complex", "children":[ { "name":"115548249 thoc1; (RefSeq) THO complex subunit 1\tK12878 THOC1; THO complex subunit 1" }, { "name":"115546636 thoc2; (RefSeq) THO complex subunit 2 isoform X1\tK12879 THOC2; THO complex subunit 2" }, { "name":"115552653 thoc3; (RefSeq) THO complex subunit 3\tK12880 THOC3; THO complex subunit 3" }, { "name":"115529505 THO complex subunit 4-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"115540441 THO complex subunit 4-like\tK12881 THOC4; THO complex subunit 4" }, { "name":"115553756 thoc5; (RefSeq) THO complex subunit 5 homolog\tK13174 THOC5; THO complex subunit 5" }, { "name":"115536139 thoc6; (RefSeq) THO complex subunit 6 homolog\tK13175 THOC6; THO complex subunit 6" }, { "name":"115557873 thoc7; (RefSeq) THO complex subunit 7 homolog\tK13176 THOC7; THO complex subunit 7" }, { "name":"115535625 chtop; (RefSeq) chromatin target of PRMT1 protein\tK28424 CHTOP; chromatin target of PRMT1 protein" } ] }, { "name":"TREX-2 complex", "children":[ { "name":"115541899 pcid2; (RefSeq) PCI domain-containing protein 2\tK23801 PCID2; nuclear mRNA export protein PCID2\/THP1" }, { "name":"115535933 sem1; (RefSeq) 26S proteasome complex subunit SEM1\tK10881 SHFM1; 26 proteasome complex subunit DSS1" }, { "name":"115535708 eny2; (RefSeq) transcription and mRNA export factor ENY2\tK11368 ENY2; enhancer of yellow 2 transcription factor" }, { "name":"115554630 transcription and mRNA export factor ENY2-2\tK11368 ENY2; enhancer of yellow 2 transcription factor" }, { "name":"115551834 cetn2; (RefSeq) centrin-2\tK10840 CETN2; centrin-2" }, { "name":"115551973 caltractin\tK10840 CETN2; centrin-2" }, { "name":"115542609 cetn3; (RefSeq) centrin-3 isoform X1\tK16466 CETN3; centrin-3" }, { "name":"115533205 mcm3ap; (RefSeq) germinal-center associated nuclear protein\tK24317 MCM3AP; germinal-center associated nuclear protein [EC:2.3.1.48]" } ] }, { "name":"Nuclear pore complex", "children":[ { "name":"115549214 nucleoprotein TPR-like isoform X1\tK09291 TPR; nucleoprotein TPR" }, { "name":"115555538 tpr; (RefSeq) nucleoprotein TPR isoform X1\tK09291 TPR; nucleoprotein TPR" }, { "name":"115557547 rae1; (RefSeq) mRNA export factor isoform X1\tK14298 RAE1; mRNA export factor" }, { "name":"115556722 protein SEC13 homolog\tK14004 SEC13; protein transport protein SEC13" }, { "name":"115556723 protein SEC13 homolog\tK14004 SEC13; protein transport protein SEC13" }, { "name":"115541467 nup37; (RefSeq) nucleoporin Nup37\tK14302 NUP37; nuclear pore complex protein Nup37" }, { "name":"115535512 nup85; (RefSeq) nuclear pore complex protein Nup85\tK14304 NUP85; nuclear pore complex protein Nup85" }, { "name":"115534089 nup43; (RefSeq) nucleoporin Nup43\tK14305 NUP43; nuclear pore complex protein Nup43" }, { "name":"115542688 nup50; (RefSeq) nuclear pore complex protein Nup50\tK14295 NUP50; nuclear pore complex protein Nup50" }, { "name":"115542881 nup54; (RefSeq) nucleoporin p54 isoform X1\tK14308 NUP54; nuclear pore complex protein Nup54" }, { "name":"115533662 nup62; (RefSeq) nuclear pore glycoprotein p62\tK14306 NUP62; nuclear pore complex protein Nup62" }, { "name":"115560798 nup88; (RefSeq) nuclear pore complex protein Nup88\tK14318 NUP88; nuclear pore complex protein Nup88" }, { "name":"115551288 nup93; (RefSeq) nuclear pore complex protein Nup93\tK14309 NUP93; nuclear pore complex protein Nup93" }, { "name":"115547041 nup98; (RefSeq) nuclear pore complex protein Nup98-Nup96 isoform X1\tK14297 NUP98; nuclear pore complex protein Nup98-Nup96" }, { "name":"115542453 nup107; (RefSeq) nuclear pore complex protein Nup107\tK14301 NUP107; nuclear pore complex protein Nup107" }, { "name":"115540428 nup133; (RefSeq) nuclear pore complex protein Nup133 isoform X1\tK14300 NUP133; nuclear pore complex protein Nup133" }, { "name":"115532104 nup188; (RefSeq) LOW QUALITY PROTEIN: nucleoporin NUP188 homolog\tK14311 NUP188; nuclear pore complex protein Nup188" }, { "name":"115535539 nup153; (RefSeq) nuclear pore complex protein Nup153 isoform X1\tK14296 NUP153; nuclear pore complex protein Nup153" }, { "name":"115551327 nup160; (RefSeq) nuclear pore complex protein Nup160\tK14303 NUP160; nuclear pore complex protein Nup160" }, { "name":"115533347 nup35; (RefSeq) nucleoporin NUP35\tK14313 NUP35; nuclear pore complex protein Nup53" }, { "name":"115550606 nup205; (RefSeq) nuclear pore complex protein Nup205 isoform X1\tK14310 NUP205; nuclear pore complex protein Nup205" }, { "name":"115543050 nup210; (RefSeq) nuclear pore membrane glycoprotein 210\tK14314 NUP210; nuclear pore complex protein Nup210" }, { "name":"115532674 nup214; (RefSeq) nuclear pore complex protein Nup214 isoform X1\tK14317 NUP214; nuclear pore complex protein Nup214" }, { "name":"115547412 pom121; (RefSeq) nuclear envelope pore membrane protein POM 121\tK14316 POM121; nuclear pore complex protein Nup121" }, { "name":"115537214 nup58; (RefSeq) nucleoporin p58\/p45 isoform X1\tK14307 NUPL1; nucleoporin p58\/p45" }, { "name":"115535942 nup42; (RefSeq) nucleoporin NUP42\tK14321 NUPL2; nucleoporin-like protein 2" }, { "name":"115548547 ndc1; (RefSeq) nucleoporin NDC1\tK14315 NDC1; nucleoporin NDC1" }, { "name":"115553676 seh1l; (RefSeq) nucleoporin SEH1\tK14299 SEH1; nucleoporin SEH1" }, { "name":"115533526 E3 SUMO-protein ligase RanBP2-like\tK12172 RANBP2; E3 SUMO-protein ligase RanBP2 [EC:2.3.2.-]" }, { "name":"115533651 E3 SUMO-protein ligase RanBP2-like isoform X1\tK12172 RANBP2; E3 SUMO-protein ligase RanBP2 [EC:2.3.2.-]" }, { "name":"115543790 sentrin-specific protease 2-like isoform X1\tK03345 SENP2; sentrin-specific protease 2 (axin associating molecule) [EC:3.4.22.68]" }, { "name":"115546238 aaas; (RefSeq) aladin\tK14320 AAAS; aladin" }, { "name":"115542609 cetn3; (RefSeq) centrin-3 isoform X1\tK16466 CETN3; centrin-3" }, { "name":"115545312 gle1; (RefSeq) nucleoporin GLE1 isoform X1\tK18723 GLE1; nucleoporin GLE1" }, { "name":"115552821 nxf1; (RefSeq) nuclear RNA export factor 1 isoform X1\tK14284 NXF; nuclear RNA export factor" }, { "name":"115552035 nxt2; (RefSeq) NTF2-related export protein 2 isoform X1\tK14285 NXT1_2; NTF2-related export protein 1\/2" } ] }, { "name":"Ran-mediated transport factors", "children":[ { "name":"115552593 ran; (RefSeq) GTP-binding nuclear protein Ran isoform X1\tK07936 RAN; GTP-binding nuclear protein Ran" }, { "name":"115558615 anp32a; (RefSeq) acidic leucine-rich nuclear phosphoprotein 32 family member A isoform X1\tK18646 ANP32A_C_D; acidic leucine-rich nuclear phosphoprotein 32 family member A\/C\/D" }, { "name":"115529167 acidic leucine-rich nuclear phosphoprotein 32 family member D-like\tK18647 ANP32B; acidic leucine-rich nuclear phosphoprotein 32 family member B" }, { "name":"115540734 anp32b; (RefSeq) acidic leucine-rich nuclear phosphoprotein 32 family member B\tK18647 ANP32B; acidic leucine-rich nuclear phosphoprotein 32 family member B" }, { "name":"115543902 ELAV-like protein 1 isoform X1\tK13088 ELAVL1; ELAV-like protein 1" }, { "name":"115555728 ELAV-like protein 1 isoform X1\tK13088 ELAVL1; ELAV-like protein 1" }, { "name":"115529842 elavl2; (RefSeq) ELAV-like protein 2 isoform X1\tK13208 ELAVL2_3_4; ELAV like protein 2\/3\/4" }, { "name":"115530068 elavl3; (RefSeq) ELAV-like protein 3 isoform X1\tK13208 ELAVL2_3_4; ELAV like protein 2\/3\/4" }, { "name":"115555946 elavl4; (RefSeq) ELAV-like protein 4 isoform X1\tK13208 ELAVL2_3_4; ELAV like protein 2\/3\/4" }, { "name":"115551845 faf2; (RefSeq) FAS-associated factor 2\tK18726 FAF2; FAS-associated factor 2" }, { "name":"115554164 vcp; (RefSeq) transitional endoplasmic reticulum ATPase isoform X1\tK13525 VCP; transitional endoplasmic reticulum ATPase" }, { "name":"115544351 vcpkmt; (RefSeq) protein-lysine methyltransferase METTL21D\tK21806 VCPKMT; protein N-lysine methyltransferase METTL21D [EC:2.1.1.-]" }, { "name":"115533143 tnpo2; (RefSeq) LOW QUALITY PROTEIN: transportin-2\tK18727 TNPO2; transportin-2" }, { "name":"115540189 transportin-2\tK18727 TNPO2; transportin-2" }, { "name":"115540663 exportin-1-like\tK14290 XPO1; exportin-1" }, { "name":"115560473 exportin-1 isoform X1\tK14290 XPO1; exportin-1" }, { "name":"115541971 xpo7; (RefSeq) exportin-7 isoform X1\tK18460 XPO7; exportin-7" }, { "name":"115529456 rangap1; (RefSeq) ran GTPase-activating protein 1 isoform X1\tK14319 RANGAP1; Ran GTPase-activating protein 1" }, { "name":"115531417 ran GTPase-activating protein 1-like isoform X1\tK14319 RANGAP1; Ran GTPase-activating protein 1" }, { "name":"115550479 nutf2; (RefSeq) nuclear transport factor 2\tK28773 NUTF2; nuclear transport factor 2" } ] }, { "name":"eIF4F and regulatory proteins", "children":[ { "name":"115529754 eukaryotic translation initiation factor 4E type 2-like isoform X1\tK03259 EIF4E; translation initiation factor 4E" }, { "name":"115548845 eif4e2; (RefSeq) eukaryotic translation initiation factor 4E type 2\tK03259 EIF4E; translation initiation factor 4E" }, { "name":"115552327 eukaryotic translation initiation factor 4E-1A-like isoform X1\tK03259 EIF4E; translation initiation factor 4E" }, { "name":"115559718 eukaryotic translation initiation factor 4E-like\tK03259 EIF4E; translation initiation factor 4E" }, { "name":"115529437 eukaryotic initiation factor 4A-I-like\tK03257 EIF4A; translation initiation factor 4A" }, { "name":"115548466 eif4a2; (RefSeq) eukaryotic initiation factor 4A-II\tK03257 EIF4A; translation initiation factor 4A" }, { "name":"115548395 eukaryotic translation initiation factor 4 gamma 1-like isoform X1\tK03260 EIF4G; translation initiation factor 4G" }, { "name":"115550580 eukaryotic translation initiation factor 4 gamma 2-like isoform X1\tK03260 EIF4G; translation initiation factor 4G" }, { "name":"115557217 eif4g3; (RefSeq) eukaryotic translation initiation factor 4 gamma 3 isoform X1\tK03260 EIF4G; translation initiation factor 4G" }, { "name":"115558235 eif4g2; (RefSeq) eukaryotic translation initiation factor 4 gamma 2 isoform X1\tK03260 EIF4G; translation initiation factor 4G" }, { "name":"115560968 LOW QUALITY PROTEIN: eukaryotic translation initiation factor 4 gamma 1-like\tK03260 EIF4G; translation initiation factor 4G" }, { "name":"115556838 eif4b; (RefSeq) eukaryotic translation initiation factor 4B isoform X1\tK03258 EIF4B; translation initiation factor 4B" }, { "name":"115560997 eif4h; (RefSeq) eukaryotic translation initiation factor 4H isoform X1\tK24086 EIF4H; translation initiation factor 4H" }, { "name":"115542755 eukaryotic translation initiation factor 4E-binding protein 2-like\tK07205 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1" }, { "name":"115545382 eukaryotic translation initiation factor 4E-binding protein 1-like\tK07205 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1" }, { "name":"115559821 eif4ebp2; (RefSeq) eukaryotic translation initiation factor 4E-binding protein 2\tK18644 EIF4EBP2; eukaryotic translation initiation factor 4E binding protein 2" }, { "name":"115552433 eif4ebp3; (RefSeq) eukaryotic translation initiation factor 4E-binding protein 3\tK18645 EIF4EBP3; eukaryotic translation initiation factor 4E binding protein 3" }, { "name":"115543960 eif4enif1; (RefSeq) eukaryotic translation initiation factor 4E transporter isoform X1\tK18728 EIF4ENIF1; eukaryotic translation initiation factor 4E transporter" }, { "name":"115534188 angel2; (RefSeq) protein angel homolog 2 isoform X1\tK18729 ANGEL; protein angel" }, { "name":"115544024 protein angel homolog 1-like\tK18729 ANGEL; protein angel" }, { "name":"115529992 fragile X mental retardation syndrome-related protein 1-like isoform X1\tK15516 FMR; fragile X mental retardation protein" }, { "name":"115552254 fmr1; (RefSeq) synaptic functional regulator FMR1 isoform X1\tK15516 FMR; fragile X mental retardation protein" }, { "name":"115555449 fxr1; (RefSeq) fragile X mental retardation syndrome-related protein 1 isoform X1\tK15516 FMR; fragile X mental retardation protein" }, { "name":"115552131 cyfip2; (RefSeq) cytoplasmic FMR1-interacting protein 2 isoform X1\tK05749 CYFIP; cytoplasmic FMR1 interacting protein" }, { "name":"115555935 cyfip1; (RefSeq) cytoplasmic FMR1-interacting protein 1\tK05749 CYFIP; cytoplasmic FMR1 interacting protein" }, { "name":"115547471 gemin5; (RefSeq) gem-associated protein 5 isoform X1\tK13133 GEMIN5; gem associated protein 5" }, { "name":"115543950 tacc3; (RefSeq) transforming acidic coiled-coil-containing protein 3 isoform X1\tK14283 TACC3; transforming acidic coiled-coil-containing protein 3" }, { "name":"115546862 cpeb4; (RefSeq) cytoplasmic polyadenylation element-binding protein 4 isoform X1\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein" }, { "name":"115552438 cytoplasmic polyadenylation element-binding protein 4-like isoform X1\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein" }, { "name":"115559004 cpeb1; (RefSeq) cytoplasmic polyadenylation element-binding protein 1 isoform X1\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein" }, { "name":"115559931 cpeb3; (RefSeq) LOW QUALITY PROTEIN: cytoplasmic polyadenylation element-binding protein 3\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein" }, { "name":"115532832 ddx3x; (RefSeq) ATP-dependent RNA helicase DDX3X isoform X1\tK11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]" }, { "name":"115546490 ATP-dependent RNA helicase DDX3X-like isoform X1\tK11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]" }, { "name":"115529547 gigyf1; (RefSeq) GRB10-interacting GYF protein 1 isoform X1\tK18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein" }, { "name":"115548399 gigyf2; (RefSeq) GRB10-interacting GYF protein 2 isoform X1\tK18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein" }, { "name":"115536203 polyadenylate-binding protein 1-like\tK13126 PABPC; polyadenylate-binding protein" }, { "name":"115543580 pabpc4; (RefSeq) polyadenylate-binding protein 4\tK13126 PABPC; polyadenylate-binding protein" }, { "name":"115553399 embryonic polyadenylate-binding protein-like isoform X1\tK13126 PABPC; polyadenylate-binding protein" }, { "name":"115553815 pabpc1; (RefSeq) polyadenylate-binding protein 1\tK13126 PABPC; polyadenylate-binding protein" }, { "name":"115554095 paip1; (RefSeq) polyadenylate-binding protein-interacting protein 1\tK14322 PAIP1; polyadenylate-binding protein-interacting protein 1" }, { "name":"115552535 paip2; (RefSeq) polyadenylate-binding protein-interacting protein 2\tK27470 PAIP2; polyadenylate-binding protein-interacting protein 2" }, { "name":"115535591 skiv2l; (RefSeq) helicase SKI2W\tK12599 SKI2; antiviral helicase SKI2 [EC:5.6.2.6]" }, { "name":"115550340 LOW QUALITY PROTEIN: deformed epidermal autoregulatory factor 1 homolog\tK23041 DEAF1; deformed epidermal autoregulatory factor 1" }, { "name":"115552325 mcts1; (RefSeq) malignant T-cell-amplified sequence 1 isoform X1\tK07575 MCTS; malignant T-cell-amplified sequence" }, { "name":"115532438 denr; (RefSeq) density-regulated protein\tK24272 DENR; density-regulated protein" } ] }, { "name":"APOBEC1-ACF complex", "children":[ { "name":"115530758 a1cf; (RefSeq) APOBEC1 complementation factor isoform X1\tK24978 A1CF; APOBEC1 complementation factor" } ] }, { "name":"Other transport factors", "children":[ { "name":"115540475 pym1; (RefSeq) partner of Y14 and mago isoform X1\tK14294 WIBG; partner of Y14 and mago" }, { "name":"115532796 hnrnpa3; (RefSeq) heterogeneous nuclear ribonucleoprotein A3 isoform X1\tK12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1\/A3" }, { "name":"115540741 heterogeneous nuclear ribonucleoprotein A1-like isoform X1\tK12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1\/A3" }, { "name":"115545469 msi1; (RefSeq) RNA-binding protein Musashi homolog 1 isoform X1\tK14411 MSI; RNA-binding protein Musashi" }, { "name":"115547227 RNA-binding protein Musashi homolog 2-like isoform X1\tK14411 MSI; RNA-binding protein Musashi" }, { "name":"115555233 dazap1; (RefSeq) DAZ-associated protein 1 isoform X1\tK14411 MSI; RNA-binding protein Musashi" }, { "name":"115557197 RNA-binding protein Musashi homolog 1-like isoform X1\tK14411 MSI; RNA-binding protein Musashi" }, { "name":"115534796 hbs1l; (RefSeq) HBS1-like protein isoform X1\tK14416 HBS1; elongation factor 1 alpha-like protein" }, { "name":"115530966 pelo; (RefSeq) protein pelota homolog\tK06965 PELO; protein pelota" }, { "name":"115537357 pabpn1; (RefSeq) polyadenylate-binding protein 2 isoform X1\tK14396 PABPN1; polyadenylate-binding protein 2" }, { "name":"115558608 pabpn1l; (RefSeq) embryonic polyadenylate-binding protein 2\tK14396 PABPN1; polyadenylate-binding protein 2" }, { "name":"115543148 ATP-dependent RNA helicase DDX19A-like\tK18655 DDX19; ATP-dependent RNA helicase DDX19\/DBP5 [EC:5.6.2.7]" }, { "name":"115556558 ATP-dependent RNA helicase DDX19A-like\tK18655 DDX19; ATP-dependent RNA helicase DDX19\/DBP5 [EC:5.6.2.7]" }, { "name":"115538679 xab2; (RefSeq) pre-mRNA-splicing factor SYF1 isoform X1\tK12867 SYF1; pre-mRNA-splicing factor SYF1" }, { "name":"115541271 sarnp; (RefSeq) SAP domain-containing ribonucleoprotein isoform X1\tK18732 SARNP; SAP domain-containing ribonucleoprotein" }, { "name":"115554301 rcc1; (RefSeq) regulator of chromosome condensation\tK11493 RCC1; regulator of chromosome condensation" }, { "name":"115558584 larp6; (RefSeq) la-related protein 6\tK18733 LARP6; la-related protein 6" }, { "name":"115546751 transcriptional activator protein Pur-alpha-like\tK21772 PURA; transcriptional activator protein Pur-alpha" }, { "name":"115551883 transcriptional activator protein Pur-alpha-like\tK21772 PURA; transcriptional activator protein Pur-alpha" }, { "name":"115531926 transcriptional activator protein Pur-beta-like\tK21799 PURB; transcriptional activator protein Pur-beta" }, { "name":"115546065 transcriptional activator protein Pur-beta\tK21799 PURB; transcriptional activator protein Pur-beta" }, { "name":"115559690 poldip3; (RefSeq) polymerase delta-interacting protein 3\tK22414 POLDIP3; polymerase delta-interacting protein 3" }, { "name":"115546857 LOW QUALITY PROTEIN: zinc finger CCCH domain-containing protein 11A-like\tK22415 ZC3H11; zinc finger CCCH domain-containing protein 11" }, { "name":"115553929 leng8; (RefSeq) leukocyte receptor cluster member 8 isoform X1\tK23802 LENG8; SAC3 family protein LENG8\/THP3" }, { "name":"115531692 protein PAT1 homolog 2-like isoform X1\tK24823 PATL2; protein PAT1 homolog 2" }, { "name":"115548520 fyttd1; (RefSeq) LOW QUALITY PROTEIN: UAP56-interacting factor\tK28772 FYTTD1; UAP56-interacting factor" } ] } ] }, { "name":"Surveillance factors", "children":[ { "name":"Surveillance complex", "children":[ { "name":"115552028 etf1; (RefSeq) eukaryotic peptide chain release factor subunit 1 isoform X1\tK03265 ETF1; peptide chain release factor subunit 1" }, { "name":"115531395 gspt1; (RefSeq) eukaryotic peptide chain release factor GTP-binding subunit ERF3A isoform X1\tK03267 ERF3; peptide chain release factor subunit 3" }, { "name":"115539412 eukaryotic peptide chain release factor GTP-binding subunit ERF3A-like\tK03267 ERF3; peptide chain release factor subunit 3" }, { "name":"115555808 upf1; (RefSeq) regulator of nonsense transcripts 1 isoform X1\tK14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3]" }, { "name":"115531935 upf2; (RefSeq) regulator of nonsense transcripts 2 isoform X1\tK14327 UPF2; regulator of nonsense transcripts 2" }, { "name":"115533679 upf3a; (RefSeq) regulator of nonsense transcripts 3A isoform X1\tK14328 UPF3; regulator of nonsense transcripts 3" }, { "name":"115552005 upf3b; (RefSeq) regulator of nonsense transcripts 3B\tK14328 UPF3; regulator of nonsense transcripts 3" } ] }, { "name":"Protein phosphatase 2A", "children":[ { "name":"115545296 ppp2cb; (RefSeq) serine\/threonine-protein phosphatase 2A catalytic subunit beta isoform\tK04382 PPP2C; serine\/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]" }, { "name":"115546624 ppp2ca; (RefSeq) serine\/threonine-protein phosphatase 2A catalytic subunit alpha isoform\tK04382 PPP2C; serine\/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]" }, { "name":"115552306 serine\/threonine-protein phosphatase 2A catalytic subunit alpha isoform\tK04382 PPP2C; serine\/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]" }, { "name":"115560872 serine\/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform\tK03456 PPP2R1; serine\/threonine-protein phosphatase 2A regulatory subunit A" }, { "name":"115531978 serine\/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform-like\tK04354 PPP2R2; serine\/threonine-protein phosphatase 2A regulatory subunit B" }, { "name":"115540950 serine\/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform-like\tK04354 PPP2R2; serine\/threonine-protein phosphatase 2A regulatory subunit B" }, { "name":"115552113 serine\/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform\tK04354 PPP2R2; serine\/threonine-protein phosphatase 2A regulatory subunit B" }, { "name":"115552320 serine\/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform isoform X1\tK04354 PPP2R2; serine\/threonine-protein phosphatase 2A regulatory subunit B" }, { "name":"115553361 LOW QUALITY PROTEIN: serine\/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform-like\tK04354 PPP2R2; serine\/threonine-protein phosphatase 2A regulatory subunit B" }, { "name":"115559824 ppp2r2d; (RefSeq) serine\/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform\tK04354 PPP2R2; serine\/threonine-protein phosphatase 2A regulatory subunit B" }, { "name":"115533185 serine\/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta-like isoform X1\tK11583 PPP2R3; serine\/threonine-protein phosphatase 2A regulatory subunit B''" }, { "name":"115543702 ppp2r3a; (RefSeq) serine\/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha isoform X1\tK11583 PPP2R3; serine\/threonine-protein phosphatase 2A regulatory subunit B''" }, { "name":"115544169 ppp2r3c; (RefSeq) serine\/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma\tK11583 PPP2R3; serine\/threonine-protein phosphatase 2A regulatory subunit B''" }, { "name":"115529926 ppp2r5b; (RefSeq) serine\/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform\tK11584 PPP2R5; serine\/threonine-protein phosphatase 2A regulatory subunit B'" }, { "name":"115534178 ppp2r5a; (RefSeq) LOW QUALITY PROTEIN: serine\/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform\tK11584 PPP2R5; serine\/threonine-protein phosphatase 2A regulatory subunit B'" }, { "name":"115534615 serine\/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform-like isoform X1\tK11584 PPP2R5; serine\/threonine-protein phosphatase 2A regulatory subunit B'" }, { "name":"115543469 ppp2r5e; (RefSeq) serine\/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform isoform X1\tK11584 PPP2R5; serine\/threonine-protein phosphatase 2A regulatory subunit B'" }, { "name":"115543864 serine\/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform\tK11584 PPP2R5; serine\/threonine-protein phosphatase 2A regulatory subunit B'" }, { "name":"115559440 ppp2r5d; (RefSeq) serine\/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform isoform X1\tK11584 PPP2R5; serine\/threonine-protein phosphatase 2A regulatory subunit B'" } ] }, { "name":"Other surveillance factors", "children":[ { "name":"115561411 smg1; (RefSeq) serine\/threonine-protein kinase SMG1 isoform X1\tK08873 SMG1; serine\/threonine-protein kinase SMG1 [EC:2.7.11.1]" }, { "name":"115554048 smg5; (RefSeq) protein SMG5\tK11125 SMG5; protein SMG5" }, { "name":"115546916 smg6; (RefSeq) telomerase-binding protein EST1A\tK11124 SMG6; protein SMG6 [EC:3.1.-.-]" }, { "name":"115548902 smg7; (RefSeq) protein SMG7 isoform X1\tK14409 SMG7; protein SMG7" }, { "name":"115547477 smg8; (RefSeq) protein SMG8\tK18734 SMG8; protein SMG8" }, { "name":"115554484 smg9; (RefSeq) protein SMG9\tK18735 SMG9; protein SMG9" }, { "name":"115529547 gigyf1; (RefSeq) GRB10-interacting GYF protein 1 isoform X1\tK18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein" }, { "name":"115548399 gigyf2; (RefSeq) GRB10-interacting GYF protein 2 isoform X1\tK18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein" }, { "name":"115558401 secisbp2l; (RefSeq) selenocysteine insertion sequence-binding protein 2-like isoform X1\tK19539 SECISBP2; selenocysteine insertion sequence-binding protein 2" }, { "name":"115560791 dhx34; (RefSeq) probable ATP-dependent RNA helicase DHX34\tK20101 DHX34; ATP-dependent RNA helicase DHX34 [EC:5.6.2.6]" }, { "name":"115535332 GTP-binding protein 1-like isoform X1\tK24887 GTPBP1; GTP-binding protein 1" }, { "name":"115540392 GTP-binding protein 1-like isoform X1\tK24887 GTPBP1; GTP-binding protein 1" } ] } ] }, { "name":"Factors involved in mRNA localization", "children":[ { "name":"Cargo complex", "children":[ { "name":"115532146 pum3; (RefSeq) LOW QUALITY PROTEIN: pumilio homolog 3\tK14844 PUF6; pumilio homology domain family member 6" }, { "name":"115542147 myo5b; (RefSeq) unconventional myosin-Vb isoform X1\tK10357 MYO5; myosin V" }, { "name":"115550650 unconventional myosin-Va-like isoform X1\tK10357 MYO5; myosin V" }, { "name":"115550651 myo5c; (RefSeq) unconventional myosin-Vc\tK10357 MYO5; myosin V" }, { "name":"115558901 myo5a; (RefSeq) unconventional myosin-Va isoform X1\tK10357 MYO5; myosin V" }, { "name":"115532355 protein bicaudal D homolog 1-like isoform X1\tK18739 BICD; protein bicaudal D" }, { "name":"115542466 protein bicaudal D homolog 2-like isoform X1\tK18739 BICD; protein bicaudal D" }, { "name":"115545066 protein bicaudal D homolog 2-like isoform X1\tK18739 BICD; protein bicaudal D" }, { "name":"115551514 bicd1; (RefSeq) protein bicaudal D homolog 1 isoform X1\tK18739 BICD; protein bicaudal D" }, { "name":"115556700 protein bicaudal D homolog 2-like isoform X1\tK18739 BICD; protein bicaudal D" }, { "name":"115543420 exd1; (RefSeq) piRNA biogenesis protein EXD1\tK18740 EXD1; exonuclease 3'-5' domain-containing protein 1" } ] }, { "name":"Factors that have mRNA localization signals", "children":[ { "name":"115537346 actin, cytoplasmic 1-like\tK05692 ACTB_G1; actin beta\/gamma 1" }, { "name":"115539010 actg1; (RefSeq) actin, cytoplasmic 2\tK05692 ACTB_G1; actin beta\/gamma 1" }, { "name":"115540271 actin, cytoplasmic 1-like\tK05692 ACTB_G1; actin beta\/gamma 1" }, { "name":"115535756 uncharacterized protein LOC115535756 isoform X1\tK17269 MBP; myelin basic protein" }, { "name":"115554623 mbp; (RefSeq) LOW QUALITY PROTEIN: myelin basic protein\tK17269 MBP; myelin basic protein" }, { "name":"115537337 vim; (RefSeq) vimentin isoform X1\tK07606 VIM; vimentin" }, { "name":"115549515 vimentin A2-like\tK07606 VIM; vimentin" }, { "name":"115537135 myc; (RefSeq) LOW QUALITY PROTEIN: myc proto-oncogene protein\tK04377 MYC; Myc proto-oncogene protein" }, { "name":"115531573 T-box transcription factor TBX6-like\tK10180 TBX6; T-box protein 6" }, { "name":"115542211 T-box protein VegT-B-like\tK10180 TBX6; T-box protein 6" }, { "name":"115553887 T-box-containing protein TBX6L-like\tK10180 TBX6; T-box protein 6" }, { "name":"115544523 nanos1; (RefSeq) nanos homolog 1\tK18741 NANOS1; protein nanos 1" } ] }, { "name":"Trans-acting binding proteins", "children":[ { "name":"115540192 khsrp; (RefSeq) far upstream element-binding protein 2 isoform X1\tK13210 FUBP; far upstream element-binding protein" }, { "name":"115542096 fubp3; (RefSeq) far upstream element-binding protein 3 isoform X1\tK13210 FUBP; far upstream element-binding protein" }, { "name":"115545032 far upstream element-binding protein 3-like isoform X1\tK13210 FUBP; far upstream element-binding protein" }, { "name":"115549576 fubp1; (RefSeq) far upstream element-binding protein 1 isoform X1\tK13210 FUBP; far upstream element-binding protein" }, { "name":"115536142 elongation factor 1-alpha\tK03231 EEF1A; elongation factor 1-alpha" }, { "name":"115536143 elongation factor 1-alpha-like\tK03231 EEF1A; elongation factor 1-alpha" }, { "name":"115537138 elongation factor 1-alpha-like\tK03231 EEF1A; elongation factor 1-alpha" }, { "name":"115559686 elongation factor 1-alpha, somatic form\tK03231 EEF1A; elongation factor 1-alpha" }, { "name":"115551976 eef1g; (RefSeq) elongation factor 1-gamma\tK03233 EEF1G; elongation factor 1-gamma" }, { "name":"115535526 hax1; (RefSeq) HCLS1-associated protein X-1\tK16220 HAX1; HCLS1-associated protein X-1" }, { "name":"115529785 arf-GAP domain and FG repeat-containing protein 2-like isoform X1\tK15044 AGFG1; Arf-GAP domain and FG repeats-containing protein 1" }, { "name":"115549620 arf-GAP domain and FG repeat-containing protein 1-like isoform X1\tK15044 AGFG1; Arf-GAP domain and FG repeats-containing protein 1" }, { "name":"115560948 agfg1; (RefSeq) arf-GAP domain and FG repeat-containing protein 1 isoform X1\tK15044 AGFG1; Arf-GAP domain and FG repeats-containing protein 1" }, { "name":"115536891 double-stranded RNA-binding protein Staufen homolog 2-like isoform X1\tK17597 STAU; double-stranded RNA-binding protein Staufen" }, { "name":"115556899 stau1; (RefSeq) LOW QUALITY PROTEIN: double-stranded RNA-binding protein Staufen homolog 1\tK17597 STAU; double-stranded RNA-binding protein Staufen" }, { "name":"115535775 insulin-like growth factor 2 mRNA-binding protein 3 isoform X1\tK13197 IGF2BP3; insulin-like growth factor 2 mRNA-binding protein 3" }, { "name":"115543685 polypyrimidine tract-binding protein 1-like isoform X1\tK13218 PTBP1; polypyrimidine tract-binding protein 1" }, { "name":"115555457 polypyrimidine tract-binding protein 1-like isoform X1\tK13218 PTBP1; polypyrimidine tract-binding protein 1" }, { "name":"115546862 cpeb4; (RefSeq) cytoplasmic polyadenylation element-binding protein 4 isoform X1\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein" }, { "name":"115552438 cytoplasmic polyadenylation element-binding protein 4-like isoform X1\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein" }, { "name":"115559004 cpeb1; (RefSeq) cytoplasmic polyadenylation element-binding protein 1 isoform X1\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein" }, { "name":"115559931 cpeb3; (RefSeq) LOW QUALITY PROTEIN: cytoplasmic polyadenylation element-binding protein 3\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein" } ] }, { "name":"Other mRNA localization factors", "children":[ { "name":"115529992 fragile X mental retardation syndrome-related protein 1-like isoform X1\tK15516 FMR; fragile X mental retardation protein" }, { "name":"115552254 fmr1; (RefSeq) synaptic functional regulator FMR1 isoform X1\tK15516 FMR; fragile X mental retardation protein" }, { "name":"115555449 fxr1; (RefSeq) fragile X mental retardation syndrome-related protein 1 isoform X1\tK15516 FMR; fragile X mental retardation protein" }, { "name":"115552131 cyfip2; (RefSeq) cytoplasmic FMR1-interacting protein 2 isoform X1\tK05749 CYFIP; cytoplasmic FMR1 interacting protein" }, { "name":"115555935 cyfip1; (RefSeq) cytoplasmic FMR1-interacting protein 1\tK05749 CYFIP; cytoplasmic FMR1 interacting protein" }, { "name":"115546328 poly(rC)-binding protein 2 isoform X1\tK13162 PCBP2; poly(rC)-binding protein 2" }, { "name":"115557155 poly(rC)-binding protein 2-like\tK13162 PCBP2; poly(rC)-binding protein 2" }, { "name":"115533419 poly(rC)-binding protein 3 isoform X1\tK21444 PCBP3_4; poly(rC)-binding protein 3\/4" }, { "name":"115541645 poly(rC)-binding protein 3-like isoform X1\tK21444 PCBP3_4; poly(rC)-binding protein 3\/4" }, { "name":"115549040 poly(rC)-binding protein 4-like\tK21444 PCBP3_4; poly(rC)-binding protein 3\/4" }, { "name":"115556919 poly(rC)-binding protein 2-like\tK21444 PCBP3_4; poly(rC)-binding protein 3\/4" }, { "name":"115560139 poly(rC)-binding protein 3-like\tK21444 PCBP3_4; poly(rC)-binding protein 3\/4" }, { "name":"115550923 caprin1; (RefSeq) caprin-1 isoform X1\tK18743 CAPRIN1; caprin-1" }, { "name":"115559327 caprin-1-like isoform X1\tK18743 CAPRIN1; caprin-1" }, { "name":"115542450 caprin2; (RefSeq) caprin-2 isoform X1\tK18744 CAPRIN2; caprin-2" }, { "name":"115554244 LOW QUALITY PROTEIN: nuclease-sensitive element-binding protein 1-like\tK09276 YBX1; Y-box-binding protein 1" } ] } ] }, { "name":"mRNA cycle factors", "children":[ { "name":"Common to processing body (P body) and stress granule", "children":[ { "name":"115548581 xrn1; (RefSeq) 5'-3' exoribonuclease 1 isoform X1\tK12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]" }, { "name":"115535614 protein argonaute-4 isoform X1\tK11593 ELF2C; eukaryotic translation initiation factor 2C" }, { "name":"115535672 protein argonaute-3 isoform X1\tK11593 ELF2C; eukaryotic translation initiation factor 2C" }, { "name":"115535926 protein argonaute-2 isoform X1\tK11593 ELF2C; eukaryotic translation initiation factor 2C" }, { "name":"115545257 protein argonaute-3-like isoform X1\tK11593 ELF2C; eukaryotic translation initiation factor 2C" }, { "name":"115545258 protein argonaute-1 isoform X1\tK11593 ELF2C; eukaryotic translation initiation factor 2C" }, { "name":"115529754 eukaryotic translation initiation factor 4E type 2-like isoform X1\tK03259 EIF4E; translation initiation factor 4E" }, { "name":"115548845 eif4e2; (RefSeq) eukaryotic translation initiation factor 4E type 2\tK03259 EIF4E; translation initiation factor 4E" }, { "name":"115552327 eukaryotic translation initiation factor 4E-1A-like isoform X1\tK03259 EIF4E; translation initiation factor 4E" }, { "name":"115559718 eukaryotic translation initiation factor 4E-like\tK03259 EIF4E; translation initiation factor 4E" }, { "name":"115555808 upf1; (RefSeq) regulator of nonsense transcripts 1 isoform X1\tK14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3]" }, { "name":"115532832 ddx3x; (RefSeq) ATP-dependent RNA helicase DDX3X isoform X1\tK11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]" }, { "name":"115546490 ATP-dependent RNA helicase DDX3X-like isoform X1\tK11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]" }, { "name":"115535668 probable ATP-dependent RNA helicase ddx6\tK12614 DDX6; ATP-dependent RNA helicase DDX6\/DHH1 [EC:5.6.2.7]" }, { "name":"115553416 probable ATP-dependent RNA helicase ddx6\tK12614 DDX6; ATP-dependent RNA helicase DDX6\/DHH1 [EC:5.6.2.7]" }, { "name":"115560807 ddx6; (RefSeq) probable ATP-dependent RNA helicase DDX6\tK12614 DDX6; ATP-dependent RNA helicase DDX6\/DHH1 [EC:5.6.2.7]" }, { "name":"115545594 RNA-binding protein MEX3B-like\tK15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]" }, { "name":"115549434 RNA-binding protein MEX3B-like\tK15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]" }, { "name":"115553513 mex3a; (RefSeq) RNA-binding protein MEX3A\tK15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]" }, { "name":"115558642 mex3b; (RefSeq) RNA-binding protein MEX3B\tK15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]" }, { "name":"115548654 fastk; (RefSeq) LOW QUALITY PROTEIN: fas-activated serine\/threonine kinase\tK08290 FASTK; Fas-activated serine\/threonine kinase [EC:2.7.11.8]" }, { "name":"115544238 protein LSM14 homolog B-like isoform X1\tK18749 LSM14; protein LSM14" }, { "name":"115550251 protein LSM14 homolog A-like isoform X1\tK18749 LSM14; protein LSM14" }, { "name":"115557167 protein LSM14 homolog B-like isoform X1\tK18749 LSM14; protein LSM14" }, { "name":"115558995 protein LSM14 homolog A-like isoform X1\tK18749 LSM14; protein LSM14" }, { "name":"115546328 poly(rC)-binding protein 2 isoform X1\tK13162 PCBP2; poly(rC)-binding protein 2" }, { "name":"115557155 poly(rC)-binding protein 2-like\tK13162 PCBP2; poly(rC)-binding protein 2" }, { "name":"115554244 LOW QUALITY PROTEIN: nuclease-sensitive element-binding protein 1-like\tK09276 YBX1; Y-box-binding protein 1" }, { "name":"115529681 LIM domain-containing protein ajuba-like\tK16682 AJUBA; LIM domain-containing protein" }, { "name":"115545398 limd1; (RefSeq) LIM domain-containing protein 1\tK16682 AJUBA; LIM domain-containing protein" }, { "name":"115558424 Wilms tumor protein 1-interacting protein homolog\tK16682 AJUBA; LIM domain-containing protein" }, { "name":"115553646 mov10; (RefSeq) helicase MOV-10\tK18422 MOV10; helicase MOV-10 [EC:5.6.2.5]" }, { "name":"115553654 putative helicase mov-10-B.1\tK18422 MOV10; helicase MOV-10 [EC:5.6.2.5]" }, { "name":"115545578 proline-rich nuclear receptor coactivator 2-like\tK18751 PNRC2; proline-rich nuclear receptor coactivator 2" }, { "name":"115542810 tnpo1; (RefSeq) transportin-1 isoform X1\tK18752 TNPO1; transportin-1" }, { "name":"115561411 smg1; (RefSeq) serine\/threonine-protein kinase SMG1 isoform X1\tK08873 SMG1; serine\/threonine-protein kinase SMG1 [EC:2.7.11.1]" }, { "name":"115554048 smg5; (RefSeq) protein SMG5\tK11125 SMG5; protein SMG5" }, { "name":"115546916 smg6; (RefSeq) telomerase-binding protein EST1A\tK11124 SMG6; protein SMG6 [EC:3.1.-.-]" }, { "name":"115548902 smg7; (RefSeq) protein SMG7 isoform X1\tK14409 SMG7; protein SMG7" }, { "name":"115534463 zfp36l1; (RefSeq) mRNA decay activator protein ZFP36L1\tK18753 ZFP36L; butyrate response factor" }, { "name":"115559628 LOW QUALITY PROTEIN: mRNA decay activator protein ZFP36L2-like\tK18753 ZFP36L; butyrate response factor" }, { "name":"115561683 mRNA decay activator protein ZFP36-like\tK18753 ZFP36L; butyrate response factor" }, { "name":"115561731 mRNA decay activator protein ZFP36L1-like\tK18753 ZFP36L; butyrate response factor" }, { "name":"115534700 protein lin-28 homolog A-like\tK18754 LIN28; protein lin-28" }, { "name":"115536384 protein lin-28 homolog A-like\tK18754 LIN28; protein lin-28" }, { "name":"115554722 lin28a; (RefSeq) protein lin-28 homolog A isoform X1\tK18754 LIN28; protein lin-28" }, { "name":"115539773 htt; (RefSeq) huntingtin isoform X1\tK04533 HD; huntingtin" }, { "name":"115542448 ipo8; (RefSeq) importin-8 isoform X1\tK18755 IPO8; importin-8" }, { "name":"115552888 protein bicaudal C homolog 1-A-like\tK18756 BICC1; protein bicaudal C" }, { "name":"115559969 bicc1; (RefSeq) protein bicaudal C homolog 1\tK18756 BICC1; protein bicaudal C" }, { "name":"115532796 hnrnpa3; (RefSeq) heterogeneous nuclear ribonucleoprotein A3 isoform X1\tK12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1\/A3" }, { "name":"115540741 heterogeneous nuclear ribonucleoprotein A1-like isoform X1\tK12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1\/A3" }, { "name":"115530003 cAMP-dependent protein kinase catalytic subunit alpha isoform X1\tK04345 PKA; protein kinase A [EC:2.7.11.11]" }, { "name":"115540768 cAMP-dependent protein kinase catalytic subunit alpha-like isoform X1\tK04345 PKA; protein kinase A [EC:2.7.11.11]" }, { "name":"115548285 cAMP-dependent protein kinase catalytic subunit beta isoform X1\tK04345 PKA; protein kinase A [EC:2.7.11.11]" }, { "name":"115555588 prkacb; (RefSeq) cAMP-dependent protein kinase catalytic subunit beta isoform X1\tK04345 PKA; protein kinase A [EC:2.7.11.11]" }, { "name":"115544461 la-related protein 1B-like isoform X1\tK18757 LARP1; la-related protein 1" }, { "name":"115546613 larp1; (RefSeq) la-related protein 1 isoform X1\tK18757 LARP1; la-related protein 1" }, { "name":"115530696 ataxin-2-like protein isoform X1\tK23625 ATXN2; ataxin-2" }, { "name":"115535370 atxn2l; (RefSeq) ataxin-2-like protein isoform X1\tK23625 ATXN2; ataxin-2" }, { "name":"115545362 atxn2; (RefSeq) ataxin-2 isoform X1\tK23625 ATXN2; ataxin-2" } ] }, { "name":"P-body specific factors", "children":[ { "name":"115560809 dcp2; (RefSeq) m7GpppN-mRNA hydrolase\tK12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62]" }, { "name":"115546590 dcp1a; (RefSeq) mRNA-decapping enzyme 1A isoform X1\tK12610 DCP1A; mRNA-decapping enzyme 1A [EC:3.-.-.-]" }, { "name":"115532663 LOW QUALITY PROTEIN: mRNA-decapping enzyme 1B-like\tK12611 DCP1B; mRNA-decapping enzyme 1B [EC:3.-.-.-]" }, { "name":"115553733 lsm1; (RefSeq) U6 snRNA-associated Sm-like protein LSm1\tK12620 LSM1; U6 snRNA-associated Sm-like protein LSm1" }, { "name":"115555401 lsm2; (RefSeq) U6 snRNA-associated Sm-like protein LSm2\tK12621 LSM2; U6 snRNA-associated Sm-like protein LSm2" }, { "name":"115557534 lsm3; (RefSeq) U6 snRNA-associated Sm-like protein LSm3\tK12622 LSM3; U6 snRNA-associated Sm-like protein LSm3" }, { "name":"115556274 lsm4; (RefSeq) U6 snRNA-associated Sm-like protein LSm4\tK12623 LSM4; U6 snRNA-associated Sm-like protein LSm4" }, { "name":"115537407 lsm5; (RefSeq) U6 snRNA-associated Sm-like protein LSm5\tK12624 LSM5; U6 snRNA-associated Sm-like protein LSm5" }, { "name":"115540926 lsm6; (RefSeq) U6 snRNA-associated Sm-like protein LSm6\tK12625 LSM6; U6 snRNA-associated Sm-like protein LSm6" }, { "name":"115555571 lsm7; (RefSeq) U6 snRNA-associated Sm-like protein LSm7\tK12626 LSM7; U6 snRNA-associated Sm-like protein LSm7" }, { "name":"115542482 lsm8; (RefSeq) LSM8 homolog, U6 small nuclear RNA associated\tK12627 LSM8; U6 snRNA-associated Sm-like protein LSm8" }, { "name":"115529782 klc2; (RefSeq) LOW QUALITY PROTEIN: kinesin light chain 2\tK10407 KLC; kinesin light chain" }, { "name":"115543639 klc1; (RefSeq) kinesin light chain 1 isoform X1\tK10407 KLC; kinesin light chain" }, { "name":"115560307 kinesin light chain 1-like isoform X1\tK10407 KLC; kinesin light chain" }, { "name":"115561490 kinesin light chain 1-like isoform X1\tK10407 KLC; kinesin light chain" }, { "name":"115542147 myo5b; (RefSeq) unconventional myosin-Vb isoform X1\tK10357 MYO5; myosin V" }, { "name":"115550650 unconventional myosin-Va-like isoform X1\tK10357 MYO5; myosin V" }, { "name":"115550651 myo5c; (RefSeq) unconventional myosin-Vc\tK10357 MYO5; myosin V" }, { "name":"115558901 myo5a; (RefSeq) unconventional myosin-Va isoform X1\tK10357 MYO5; myosin V" }, { "name":"115533128 tubulin alpha chain-like isoform X1\tK07374 TUBA; tubulin alpha" }, { "name":"115533159 tubulin alpha chain\tK07374 TUBA; tubulin alpha" }, { "name":"115533160 tubulin alpha chain-like\tK07374 TUBA; tubulin alpha" }, { "name":"115537591 tubulin alpha chain, testis-specific-like\tK07374 TUBA; tubulin alpha" }, { "name":"115541220 tubulin alpha chain-like\tK07374 TUBA; tubulin alpha" }, { "name":"115541644 tubulin alpha-1C chain-like\tK07374 TUBA; tubulin alpha" }, { "name":"115547025 tubulin alpha chain isoform X1\tK07374 TUBA; tubulin alpha" }, { "name":"115549883 tubulin alpha-8 chain-like\tK07374 TUBA; tubulin alpha" }, { "name":"115558849 tubulin alpha chain isoform X1\tK07374 TUBA; tubulin alpha" }, { "name":"115559022 tubulin alpha chain-like\tK07374 TUBA; tubulin alpha" }, { "name":"115546862 cpeb4; (RefSeq) cytoplasmic polyadenylation element-binding protein 4 isoform X1\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein" }, { "name":"115552438 cytoplasmic polyadenylation element-binding protein 4-like isoform X1\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein" }, { "name":"115559004 cpeb1; (RefSeq) cytoplasmic polyadenylation element-binding protein 1 isoform X1\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein" }, { "name":"115559931 cpeb3; (RefSeq) LOW QUALITY PROTEIN: cytoplasmic polyadenylation element-binding protein 3\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein" }, { "name":"115547471 gemin5; (RefSeq) gem-associated protein 5 isoform X1\tK13133 GEMIN5; gem associated protein 5" }, { "name":"115543950 tacc3; (RefSeq) transforming acidic coiled-coil-containing protein 3 isoform X1\tK14283 TACC3; transforming acidic coiled-coil-containing protein 3" }, { "name":"115531481 LOW QUALITY PROTEIN: trinucleotide repeat-containing gene 6B protein-like\tK18412 TNRC6; trinucleotide repeat-containing gene 6 protein" }, { "name":"115541023 LOW QUALITY PROTEIN: trinucleotide repeat-containing gene 6C protein-like\tK18412 TNRC6; trinucleotide repeat-containing gene 6 protein" }, { "name":"115559536 tnrc6a; (RefSeq) trinucleotide repeat-containing gene 6A protein isoform X1\tK18412 TNRC6; trinucleotide repeat-containing gene 6 protein" }, { "name":"115560677 trinucleotide repeat-containing gene 6C protein-like isoform X1\tK18412 TNRC6; trinucleotide repeat-containing gene 6 protein" }, { "name":"115561241 tnrc6b; (RefSeq) trinucleotide repeat-containing gene 6B protein isoform X1\tK18412 TNRC6; trinucleotide repeat-containing gene 6 protein" }, { "name":"115551284 cnot1; (RefSeq) CCR4-NOT transcription complex subunit 1 isoform X1\tK12604 CNOT1; CCR4-NOT transcription complex subunit 1" }, { "name":"115551247 cnot2; (RefSeq) CCR4-NOT transcription complex subunit 2 isoform X1\tK12605 CNOT2; CCR4-NOT transcription complex subunit 2" }, { "name":"115535829 CCR4-NOT transcription complex subunit 3-like isoform X1\tK12580 CNOT3; CCR4-NOT transcription complex subunit 3" }, { "name":"115553926 cnot3; (RefSeq) CCR4-NOT transcription complex subunit 3 isoform X1\tK12580 CNOT3; CCR4-NOT transcription complex subunit 3" }, { "name":"115541420 CCR4-NOT transcription complex subunit 4-like\tK10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]" }, { "name":"115550906 cnot4; (RefSeq) CCR4-NOT transcription complex subunit 4 isoform X1\tK10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]" }, { "name":"115541259 CCR4-NOT transcription complex subunit 6-like isoform X1\tK12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]" }, { "name":"115545074 cnot6l; (RefSeq) CCR4-NOT transcription complex subunit 6-like isoform X1\tK12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]" }, { "name":"115552557 CCR4-NOT transcription complex subunit 6-like\tK12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]" }, { "name":"115547832 cnot8; (RefSeq) CCR4-NOT transcription complex subunit 8\tK12581 CNOT7_8; CCR4-NOT transcription complex subunit 7\/8" }, { "name":"115552026 CCR4-NOT transcription complex subunit 7 isoform X1\tK12581 CNOT7_8; CCR4-NOT transcription complex subunit 7\/8" }, { "name":"115558992 uncharacterized protein KIAA0355 homolog\tK26671 GARRE1; granule associated Rac and RHOG effector protein 1" }, { "name":"115548892 dis3l2; (RefSeq) LOW QUALITY PROTEIN: DIS3-like exonuclease 2\tK18758 DIS3L2; DIS3-like exonuclease 2 [EC:3.1.13.-]" }, { "name":"115540449 pan2; (RefSeq) PAN2-PAN3 deadenylation complex catalytic subunit PAN2 isoform X1\tK12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4]" }, { "name":"115537635 pan3; (RefSeq) PAN2-PAN3 deadenylation complex subunit PAN3\tK12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3" }, { "name":"115529497 tob2; (RefSeq) protein Tob2\tK14443 TOB; protein Tob\/BTG" }, { "name":"115530725 tob1; (RefSeq) protein Tob1\tK14443 TOB; protein Tob\/BTG" }, { "name":"115531974 btg1; (RefSeq) protein BTG1\tK14443 TOB; protein Tob\/BTG" }, { "name":"115535558 protein Tob1-like\tK14443 TOB; protein Tob\/BTG" }, { "name":"115547030 maternal B9.10 protein-like\tK14443 TOB; protein Tob\/BTG" }, { "name":"115547772 protein BTG3-like\tK14443 TOB; protein Tob\/BTG" }, { "name":"115554487 protein BTG4-like\tK14443 TOB; protein Tob\/BTG" }, { "name":"115543960 eif4enif1; (RefSeq) eukaryotic translation initiation factor 4E transporter isoform X1\tK18728 EIF4ENIF1; eukaryotic translation initiation factor 4E transporter" }, { "name":"115540491 protein PAT1 homolog 1-like\tK12617 PATL1; DNA topoisomerase 2-associated protein PAT1" }, { "name":"115550988 edc3; (RefSeq) enhancer of mRNA-decapping protein 3 isoform X1\tK12615 EDC3; enhancer of mRNA-decapping protein 3" }, { "name":"115550478 edc4; (RefSeq) enhancer of mRNA-decapping protein 4 isoform X1\tK12616 EDC4; enhancer of mRNA-decapping protein 4" }, { "name":"115540103 nanos3; (RefSeq) nanos homolog 3\tK18761 NANOS3; protein nanos 3" }, { "name":"115531935 upf2; (RefSeq) regulator of nonsense transcripts 2 isoform X1\tK14327 UPF2; regulator of nonsense transcripts 2" }, { "name":"115533679 upf3a; (RefSeq) regulator of nonsense transcripts 3A isoform X1\tK14328 UPF3; regulator of nonsense transcripts 3" }, { "name":"115552005 upf3b; (RefSeq) regulator of nonsense transcripts 3B\tK14328 UPF3; regulator of nonsense transcripts 3" }, { "name":"115535781 trim71; (RefSeq) E3 ubiquitin-protein ligase TRIM71\tK12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]" }, { "name":"115551979 polr2g; (RefSeq) DNA-directed RNA polymerase II subunit RPB7\tK03015 RPB7; DNA-directed RNA polymerase II subunit RPB7" }, { "name":"115560248 interferon-induced, double-stranded RNA-activated protein kinase-like isoform X1\tK16195 EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1]" }, { "name":"115560249 interferon-induced, double-stranded RNA-activated protein kinase-like\tK16195 EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1]" }, { "name":"115560250 interferon-induced, double-stranded RNA-activated protein kinase-like\tK16195 EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1]" }, { "name":"115560251 interferon-induced, double-stranded RNA-activated protein kinase-like\tK16195 EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1]" }, { "name":"115547278 zar1l; (RefSeq) ZAR1-like protein\tK18762 ZAR1; zygote arrest protein 1" }, { "name":"115555490 zar1; (RefSeq) zygote arrest protein 1\tK18762 ZAR1; zygote arrest protein 1" }, { "name":"115536962 ythdf3; (RefSeq) YTH domain-containing family protein 3 isoform X1\tK20102 YTHDF; YTH domain-containing family protein" }, { "name":"115542744 YTH domain-containing family protein 1-like isoform X1\tK20102 YTHDF; YTH domain-containing family protein" }, { "name":"115543775 LOW QUALITY PROTEIN: YTH domain-containing family protein 2-like\tK20102 YTHDF; YTH domain-containing family protein" }, { "name":"115550241 YTH domain-containing family protein 1-like\tK20102 YTHDF; YTH domain-containing family protein" } ] }, { "name":"Stress granule specific factors", "children":[ { "name":"115541980 nucleolysin TIA-1-like isoform X1\tK13201 TIA1; nucleolysin TIA-1\/TIAR" }, { "name":"115554737 nucleolysin TIA-1-like isoform X1\tK13201 TIA1; nucleolysin TIA-1\/TIAR" }, { "name":"115560140 tial1; (RefSeq) nucleolysin TIAR isoform X1\tK13201 TIA1; nucleolysin TIA-1\/TIAR" }, { "name":"115536203 polyadenylate-binding protein 1-like\tK13126 PABPC; polyadenylate-binding protein" }, { "name":"115543580 pabpc4; (RefSeq) polyadenylate-binding protein 4\tK13126 PABPC; polyadenylate-binding protein" }, { "name":"115553399 embryonic polyadenylate-binding protein-like isoform X1\tK13126 PABPC; polyadenylate-binding protein" }, { "name":"115553815 pabpc1; (RefSeq) polyadenylate-binding protein 1\tK13126 PABPC; polyadenylate-binding protein" }, { "name":"115536891 double-stranded RNA-binding protein Staufen homolog 2-like isoform X1\tK17597 STAU; double-stranded RNA-binding protein Staufen" }, { "name":"115556899 stau1; (RefSeq) LOW QUALITY PROTEIN: double-stranded RNA-binding protein Staufen homolog 1\tK17597 STAU; double-stranded RNA-binding protein Staufen" }, { "name":"115529992 fragile X mental retardation syndrome-related protein 1-like isoform X1\tK15516 FMR; fragile X mental retardation protein" }, { "name":"115552254 fmr1; (RefSeq) synaptic functional regulator FMR1 isoform X1\tK15516 FMR; fragile X mental retardation protein" }, { "name":"115555449 fxr1; (RefSeq) fragile X mental retardation syndrome-related protein 1 isoform X1\tK15516 FMR; fragile X mental retardation protein" }, { "name":"115543902 ELAV-like protein 1 isoform X1\tK13088 ELAVL1; ELAV-like protein 1" }, { "name":"115555728 ELAV-like protein 1 isoform X1\tK13088 ELAVL1; ELAV-like protein 1" }, { "name":"115552467 g3bp1; (RefSeq) ras GTPase-activating protein-binding protein 1\tK17265 G3BP1; Ras GTPase-activating protein-binding protein 1 [EC:5.6.2.5 5.6.2.3]" }, { "name":"115540229 g3bp2; (RefSeq) ras GTPase-activating protein-binding protein 2 isoform X1\tK24983 G3BP2; Ras GTPase-activating protein-binding protein 2" }, { "name":"115561471 eif2a; (RefSeq) eukaryotic translation initiation factor 2A isoform X1\tK15026 EIF2A; translation initiation factor 2A" }, { "name":"115540384 eif3b; (RefSeq) eukaryotic translation initiation factor 3 subunit B\tK03253 EIF3B; translation initiation factor 3 subunit B" }, { "name":"115529437 eukaryotic initiation factor 4A-I-like\tK03257 EIF4A; translation initiation factor 4A" }, { "name":"115548466 eif4a2; (RefSeq) eukaryotic initiation factor 4A-II\tK03257 EIF4A; translation initiation factor 4A" }, { "name":"115539941 eif4a3; (RefSeq) eukaryotic initiation factor 4A-III\tK13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7]" }, { "name":"115556838 eif4b; (RefSeq) eukaryotic translation initiation factor 4B isoform X1\tK03258 EIF4B; translation initiation factor 4B" }, { "name":"115548395 eukaryotic translation initiation factor 4 gamma 1-like isoform X1\tK03260 EIF4G; translation initiation factor 4G" }, { "name":"115550580 eukaryotic translation initiation factor 4 gamma 2-like isoform X1\tK03260 EIF4G; translation initiation factor 4G" }, { "name":"115557217 eif4g3; (RefSeq) eukaryotic translation initiation factor 4 gamma 3 isoform X1\tK03260 EIF4G; translation initiation factor 4G" }, { "name":"115558235 eif4g2; (RefSeq) eukaryotic translation initiation factor 4 gamma 2 isoform X1\tK03260 EIF4G; translation initiation factor 4G" }, { "name":"115560968 LOW QUALITY PROTEIN: eukaryotic translation initiation factor 4 gamma 1-like\tK03260 EIF4G; translation initiation factor 4G" }, { "name":"115537617 ribosomal protein S6 kinase alpha-3 isoform X1\tK04373 RPS6KA; ribosomal protein S6 kinase alpha-1\/2\/3\/6 [EC:2.7.11.1]" }, { "name":"115543516 ribosomal protein S6 kinase alpha-1 isoform X1\tK04373 RPS6KA; ribosomal protein S6 kinase alpha-1\/2\/3\/6 [EC:2.7.11.1]" }, { "name":"115552339 ribosomal protein S6 kinase alpha-6 isoform X1\tK04373 RPS6KA; ribosomal protein S6 kinase alpha-1\/2\/3\/6 [EC:2.7.11.1]" }, { "name":"115559079 ribosomal protein S6 kinase alpha-2-like isoform X1\tK04373 RPS6KA; ribosomal protein S6 kinase alpha-1\/2\/3\/6 [EC:2.7.11.1]" }, { "name":"115552571 rack1; (RefSeq) receptor of activated protein C kinase 1\tK14753 RACK1; guanine nucleotide-binding protein subunit beta-2-like 1 protein" }, { "name":"115542489 TNF receptor-associated factor 2-like\tK03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]" }, { "name":"115543025 TNF receptor-associated factor 2-like\tK03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]" }, { "name":"115554517 TNF receptor-associated factor 2-like\tK03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]" }, { "name":"115552821 nxf1; (RefSeq) nuclear RNA export factor 1 isoform X1\tK14284 NXF; nuclear RNA export factor" }, { "name":"115541856 hdac6; (RefSeq) histone deacetylase 6\tK11407 HDAC6; histone deacetylase 6 [EC:3.5.1.98]" }, { "name":"115558810 tdrd3; (RefSeq) tudor domain-containing protein 3 isoform X1\tK18404 TDRD3; tudor domain-containing protein 3" }, { "name":"115540552 larp4; (RefSeq) la-related protein 4 isoform X1\tK18763 LARP4; la-related protein 4" }, { "name":"115548613 larp4b; (RefSeq) la-related protein 4B\tK18763 LARP4; la-related protein 4" }, { "name":"115557252 la-related protein 4-like isoform X1\tK18763 LARP4; la-related protein 4" } ] } ] } ] }, { "name":"mRNA degradation factors", "children":[ { "name":"5'-3' decay", "children":[ { "name":"Decapping complex", "children":[ { "name":"115546590 dcp1a; (RefSeq) mRNA-decapping enzyme 1A isoform X1\tK12610 DCP1A; mRNA-decapping enzyme 1A [EC:3.-.-.-]" }, { "name":"115532663 LOW QUALITY PROTEIN: mRNA-decapping enzyme 1B-like\tK12611 DCP1B; mRNA-decapping enzyme 1B [EC:3.-.-.-]" }, { "name":"115560809 dcp2; (RefSeq) m7GpppN-mRNA hydrolase\tK12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62]" }, { "name":"115535668 probable ATP-dependent RNA helicase ddx6\tK12614 DDX6; ATP-dependent RNA helicase DDX6\/DHH1 [EC:5.6.2.7]" }, { "name":"115553416 probable ATP-dependent RNA helicase ddx6\tK12614 DDX6; ATP-dependent RNA helicase DDX6\/DHH1 [EC:5.6.2.7]" }, { "name":"115560807 ddx6; (RefSeq) probable ATP-dependent RNA helicase DDX6\tK12614 DDX6; ATP-dependent RNA helicase DDX6\/DHH1 [EC:5.6.2.7]" }, { "name":"115550988 edc3; (RefSeq) enhancer of mRNA-decapping protein 3 isoform X1\tK12615 EDC3; enhancer of mRNA-decapping protein 3" }, { "name":"115550478 edc4; (RefSeq) enhancer of mRNA-decapping protein 4 isoform X1\tK12616 EDC4; enhancer of mRNA-decapping protein 4" }, { "name":"115540491 protein PAT1 homolog 1-like\tK12617 PATL1; DNA topoisomerase 2-associated protein PAT1" } ] }, { "name":"Lsm complex", "children":[ { "name":"115553733 lsm1; (RefSeq) U6 snRNA-associated Sm-like protein LSm1\tK12620 LSM1; U6 snRNA-associated Sm-like protein LSm1" }, { "name":"115555401 lsm2; (RefSeq) U6 snRNA-associated Sm-like protein LSm2\tK12621 LSM2; U6 snRNA-associated Sm-like protein LSm2" }, { "name":"115557534 lsm3; (RefSeq) U6 snRNA-associated Sm-like protein LSm3\tK12622 LSM3; U6 snRNA-associated Sm-like protein LSm3" }, { "name":"115556274 lsm4; (RefSeq) U6 snRNA-associated Sm-like protein LSm4\tK12623 LSM4; U6 snRNA-associated Sm-like protein LSm4" }, { "name":"115537407 lsm5; (RefSeq) U6 snRNA-associated Sm-like protein LSm5\tK12624 LSM5; U6 snRNA-associated Sm-like protein LSm5" }, { "name":"115540926 lsm6; (RefSeq) U6 snRNA-associated Sm-like protein LSm6\tK12625 LSM6; U6 snRNA-associated Sm-like protein LSm6" }, { "name":"115555571 lsm7; (RefSeq) U6 snRNA-associated Sm-like protein LSm7\tK12626 LSM7; U6 snRNA-associated Sm-like protein LSm7" }, { "name":"115542482 lsm8; (RefSeq) LSM8 homolog, U6 small nuclear RNA associated\tK12627 LSM8; U6 snRNA-associated Sm-like protein LSm8" } ] }, { "name":"5' exonucleases", "children":[ { "name":"115548581 xrn1; (RefSeq) 5'-3' exoribonuclease 1 isoform X1\tK12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]" }, { "name":"115534263 xrn2; (RefSeq) 5'-3' exoribonuclease 2 isoform X1\tK12619 XRN2; 5'-3' exoribonuclease 2 [EC:3.1.13.-]" }, { "name":"115541557 U8 snoRNA-decapping enzyme-like\tK16855 NUDT16; U8 snoRNA-decapping enzyme [EC:3.6.1.62 3.6.1.64]" } ] }, { "name":"Other 5'-3' decay factors", "children":[ { "name":"115552709 dcps; (RefSeq) m7GpppX diphosphatase\tK12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59]" }, { "name":"115540749 helz; (RefSeq) probable helicase with zinc finger domain isoform X1\tK25168 HELZ; helicase with zinc finger domain [EC:5.6.2.-]" } ] } ] }, { "name":"3'-5' decay", "children":[ { "name":"Core exosome factors", "children":[ { "name":"115540619 exosc1; (RefSeq) exosome complex component CSL4\tK07573 CSL4; exosome complex component CSL4" }, { "name":"115541410 exosc2; (RefSeq) exosome complex component RRP4\tK03679 RRP4; exosome complex component RRP4" }, { "name":"115552239 exosc3; (RefSeq) exosome complex component RRP40\tK03681 RRP40; exosome complex component RRP40" }, { "name":"115548293 exosc4; (RefSeq) exosome complex component RRP41\tK11600 RRP41; exosome complex component RRP41" }, { "name":"115560720 exosc5; (RefSeq) exosome complex component RRP46\tK12590 RRP46; exosome complex component RRP46" }, { "name":"115551081 exosc6; (RefSeq) exosome complex component MTR3\tK12587 MTR3; exosome complex component MTR3" }, { "name":"115535692 exosc7; (RefSeq) exosome complex component RRP42\tK12589 RRP42; exosome complex component RRP42" }, { "name":"115547342 exosc8; (RefSeq) exosome complex component RRP43\tK12586 RRP43; exosome complex component RRP43" }, { "name":"115540542 exosc9; (RefSeq) exosome complex component RRP45\tK03678 RRP45; exosome complex component RRP45" } ] }, { "name":"Exosome cofactors", "children":[ { "name":"115560008 dis3; (RefSeq) exosome complex exonuclease RRP44\tK12585 DIS3; exosome complex exonuclease DIS3\/RRP44 [EC:3.1.13.-]" }, { "name":"115558652 dis3l; (RefSeq) DIS3-like exonuclease 1 isoform X1\tK18681 DIS3L; DIS3-like exonuclease 1 [EC:3.1.13.-]" }, { "name":"115545533 exosc10; (RefSeq) exosome component 10\tK12591 RRP6; exosome complex exonuclease RRP6 [EC:3.1.13.-]" }, { "name":"115559721 c1d; (RefSeq) nuclear nucleic acid-binding protein C1D\tK12592 C1D; exosome complex protein LRP1" }, { "name":"115550675 mphosph6; (RefSeq) M-phase phosphoprotein 6\tK12593 MPHOSPH6; M-phase phosphoprotein 6, animal type" } ] }, { "name":"TRAMP complex", "children":[ { "name":"115535676 tent4a; (RefSeq) terminal nucleotidyltransferase 4A\tK03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5\/7 [EC:2.7.7.19]" }, { "name":"115553710 terminal nucleotidyltransferase 4A-like\tK03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5\/7 [EC:2.7.7.19]" }, { "name":"115559119 tent4b; (RefSeq) terminal nucleotidyltransferase 4B\tK03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5\/7 [EC:2.7.7.19]" }, { "name":"115540485 zcchc7; (RefSeq) zinc finger CCHC domain-containing protein 7\tK12597 AIR1_2; protein AIR1\/2" }, { "name":"115552251 zinc finger CCHC domain-containing protein 7-like\tK12597 AIR1_2; protein AIR1\/2" }, { "name":"115542591 mtrex; (RefSeq) exosome RNA helicase MTR4\tK12598 MTR4; ATP-dependent RNA helicase DOB1 [EC:5.6.2.6]" } ] }, { "name":"Ski complex", "children":[ { "name":"115535591 skiv2l; (RefSeq) helicase SKI2W\tK12599 SKI2; antiviral helicase SKI2 [EC:5.6.2.6]" }, { "name":"115544989 ttc37; (RefSeq) tetratricopeptide repeat protein 37 isoform X1\tK12600 SKI3; superkiller protein 3" }, { "name":"115550791 wdr61; (RefSeq) WD repeat-containing protein 61\tK12602 WDR61; WD repeat-containing protein 61" } ] }, { "name":"Ccr4-NOT complex", "children":[ { "name":"115541259 CCR4-NOT transcription complex subunit 6-like isoform X1\tK12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]" }, { "name":"115545074 cnot6l; (RefSeq) CCR4-NOT transcription complex subunit 6-like isoform X1\tK12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]" }, { "name":"115552557 CCR4-NOT transcription complex subunit 6-like\tK12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]" }, { "name":"115551284 cnot1; (RefSeq) CCR4-NOT transcription complex subunit 1 isoform X1\tK12604 CNOT1; CCR4-NOT transcription complex subunit 1" }, { "name":"115551247 cnot2; (RefSeq) CCR4-NOT transcription complex subunit 2 isoform X1\tK12605 CNOT2; CCR4-NOT transcription complex subunit 2" }, { "name":"115535829 CCR4-NOT transcription complex subunit 3-like isoform X1\tK12580 CNOT3; CCR4-NOT transcription complex subunit 3" }, { "name":"115553926 cnot3; (RefSeq) CCR4-NOT transcription complex subunit 3 isoform X1\tK12580 CNOT3; CCR4-NOT transcription complex subunit 3" }, { "name":"115541420 CCR4-NOT transcription complex subunit 4-like\tK10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]" }, { "name":"115550906 cnot4; (RefSeq) CCR4-NOT transcription complex subunit 4 isoform X1\tK10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]" }, { "name":"115547832 cnot8; (RefSeq) CCR4-NOT transcription complex subunit 8\tK12581 CNOT7_8; CCR4-NOT transcription complex subunit 7\/8" }, { "name":"115552026 CCR4-NOT transcription complex subunit 7 isoform X1\tK12581 CNOT7_8; CCR4-NOT transcription complex subunit 7\/8" }, { "name":"115532932 cnot9; (RefSeq) CCR4-NOT transcription complex subunit 9\tK12606 RCD1; CCR4-NOT transcription complex subunit 9" } ] }, { "name":"Pan complex", "children":[ { "name":"115540449 pan2; (RefSeq) PAN2-PAN3 deadenylation complex catalytic subunit PAN2 isoform X1\tK12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4]" }, { "name":"115537635 pan3; (RefSeq) PAN2-PAN3 deadenylation complex subunit PAN3\tK12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3" } ] }, { "name":"Other 3'-5' decay factors", "children":[ { "name":"115539882 parn; (RefSeq) poly(A)-specific ribonuclease PARN isoform X1\tK01148 PARN; poly(A)-specific ribonuclease [EC:3.1.13.4]" }, { "name":"115561021 dhx36; (RefSeq) ATP-dependent DNA\/RNA helicase DHX36\tK14442 DHX36; ATP-dependent RNA helicase DHX36 [EC:5.6.2.6]" }, { "name":"115529497 tob2; (RefSeq) protein Tob2\tK14443 TOB; protein Tob\/BTG" }, { "name":"115530725 tob1; (RefSeq) protein Tob1\tK14443 TOB; protein Tob\/BTG" }, { "name":"115531974 btg1; (RefSeq) protein BTG1\tK14443 TOB; protein Tob\/BTG" }, { "name":"115535558 protein Tob1-like\tK14443 TOB; protein Tob\/BTG" }, { "name":"115547030 maternal B9.10 protein-like\tK14443 TOB; protein Tob\/BTG" }, { "name":"115547772 protein BTG3-like\tK14443 TOB; protein Tob\/BTG" }, { "name":"115554487 protein BTG4-like\tK14443 TOB; protein Tob\/BTG" }, { "name":"115540540 noct; (RefSeq) nocturnin isoform X1\tK18764 NOCT; nocturnin [EC:3.1.3.108]" }, { "name":"115552643 nocturnin-like isoform X1\tK18764 NOCT; nocturnin [EC:3.1.3.108]" }, { "name":"115542698 eri1; (RefSeq) 3'-5' exoribonuclease 1\tK18416 THEX1; 3'-5' exoribonuclease 1 [EC:3.1.-.-]" }, { "name":"115539877 eri2; (RefSeq) ERI1 exoribonuclease 2 isoform X1\tK18417 ERI2; ERI1 exoribonuclease 2 [EC:3.1.-.-]" }, { "name":"115552709 dcps; (RefSeq) m7GpppX diphosphatase\tK12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59]" }, { "name":"115557008 pde12; (RefSeq) 2',5'-phosphodiesterase 12\tK19612 PDE12; 2',5'-phosphodiesterase [EC:3.1.13.4 3.1.4.-]" }, { "name":"115550933 ireb2; (RefSeq) iron-responsive element-binding protein 2 isoform X1\tK22416 IREB2; iron-responsive element-binding protein 2" }, { "name":"115540749 helz; (RefSeq) probable helicase with zinc finger domain isoform X1\tK25168 HELZ; helicase with zinc finger domain [EC:5.6.2.-]" }, { "name":"115530896 helz2; (RefSeq) helicase with zinc finger domain 2 isoform X1\tK25165 HELZ2; 3'-5' exoribonuclease HELZ2 [EC:3.1.13.1 5.6.2.6]" }, { "name":"115544166 nrde2; (RefSeq) protein NRDE2 homolog\tK26109 NRDE2; nuclear exosome regulator NRDE2" }, { "name":"115559317 samd4a; (RefSeq) protein Smaug homolog 1 isoform X1\tK27396 SMG; protein Smaug" }, { "name":"115561686 samd4b; (RefSeq) protein Smaug homolog 2\tK27396 SMG; protein Smaug" }, { "name":"115529364 focad; (RefSeq) focadhesin isoform X1\tK27498 FOCAD; focadhesin" } ] } ] }, { "name":"Other degradation factors", "children":[ { "name":"RNases", "children":[ { "name":"115535858 zc3h12a; (RefSeq) endoribonuclease ZC3H12A\tK18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]" }, { "name":"115542090 probable ribonuclease ZC3H12C\tK18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]" }, { "name":"115547192 zc3h12b; (RefSeq) probable ribonuclease ZC3H12B\tK18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]" }, { "name":"115554255 ribonuclease ZC3H12A-like\tK18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]" } ] } ] } ] } ] }, { "name":"Prokaryotic type", "children":[ { "name":"Bacterial mRNA degradation factors", "children":[ { "name":"RNA degradosome components", "children":[ { "name":"Ribonucreases", "children":[ { "name":"115537034 drosha; (RefSeq) ribonuclease 3\tK03685 rnc; ribonuclease III [EC:3.1.26.3]" }, { "name":"115547841 rexo2; (RefSeq) oligoribonuclease, mitochondrial\tK13288 orn; oligoribonuclease [EC:3.1.-.-]" } ] }, { "name":"Helicases" }, { "name":"Other RNA degradosome components", "children":[ { "name":"115529554 eno3; (RefSeq) beta-enolase\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]" }, { "name":"115553474 eno1; (RefSeq) alpha-enolase isoform X1\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]" }, { "name":"115553962 eno2; (RefSeq) gamma-enolase\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]" }, { "name":"115560510 pnpt1; (RefSeq) polyribonucleotide nucleotidyltransferase 1, mitochondrial isoform X1\tK00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]" }, { "name":"115533035 pfkl; (RefSeq) ATP-dependent 6-phosphofructokinase, liver type\tK00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]" }, { "name":"115537609 ATP-dependent 6-phosphofructokinase, platelet type-like isoform X1\tK00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]" }, { "name":"115540575 pfkm; (RefSeq) ATP-dependent 6-phosphofructokinase, muscle type\tK00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]" }, { "name":"115548889 pfkp; (RefSeq) ATP-dependent 6-phosphofructokinase, platelet type isoform X1\tK00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]" } ] } ] }, { "name":"Other RNA degradation factors", "children":[ { "name":"Chaperones", "children":[ { "name":"115552288 hspa9; (RefSeq) stress-70 protein, mitochondrial\tK04043 dnaK; molecular chaperone DnaK" }, { "name":"115533187 hspd1; (RefSeq) 60 kDa heat shock protein, mitochondrial\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]" } ] }, { "name":"Others" }, { "name":"Bacterial Small RNA Regulators" } ] } ] }, { "name":"Archeal mRNA degradation factors", "children":[ { "name":"Exosome components", "children":[ { "name":"Core exosome", "children":[ { "name":"115541410 exosc2; (RefSeq) exosome complex component RRP4\tK03679 RRP4; exosome complex component RRP4" }, { "name":"115540619 exosc1; (RefSeq) exosome complex component CSL4\tK07573 CSL4; exosome complex component CSL4" } ] }, { "name":"Cofactors", "children":[ { "name":"115548293 exosc4; (RefSeq) exosome complex component RRP41\tK11600 RRP41; exosome complex component RRP41" }, { "name":"115535692 exosc7; (RefSeq) exosome complex component RRP42\tK12589 RRP42; exosome complex component RRP42" } ] }, { "name":"Others" } ] } ] } ] } ] }