{
	"name":"gtm03000",
	"children":[
	{
		"name":"Eukaryotic type",
		"children":[
		{
			"name":"Basic leucine zipper (bZIP)",
			"children":[
			{
				"name":"AP-1(-like) components, Jun"
			},
			{
				"name":"AP-1(-like) components, Fos"
			},
			{
				"name":"AP-1(-like) components, Maf"
			},
			{
				"name":"AP-1(-like) components, NF-E2"
			},
			{
				"name":"AP-1(-like) components, Fungal regulators"
			},
			{
				"name":"AP-1(-like) components, CRE-BP\/ATF"
			},
			{
				"name":"CREB"
			},
			{
				"name":"C\/EBP-like factors"
			},
			{
				"name":"bZIP\/PAR"
			},
			{
				"name":"Plant bZIP factors"
			},
			{
				"name":"ZIP only"
			}
			]
		},
		{
			"name":"Basic helix-loop-helix (bHLH)",
			"children":[
			{
				"name":"Ubiquitous (class A) factors"
			},
			{
				"name":"Myogenic transcription factors"
			},
			{
				"name":"Achaete-Scute"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, Lymphoid factors"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, Mesodermal Twist-like factors"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, HEN"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, Mesp"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, Atonal"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, Pancreatic factors"
			},
			{
				"name":"Hairy, Hairy\/E(SPL)"
			},
			{
				"name":"Hairy, Fungal regulators"
			},
			{
				"name":"Factors with PAS domain"
			},
			{
				"name":"Yabby"
			},
			{
				"name":"INO"
			},
			{
				"name":"HLH domain only"
			}
			]
		},
		{
			"name":"Basic helix-loop-helix\/leucine zipper (bHLH-ZIP)",
			"children":[
			{
				"name":"Ubiquitous bHLH-ZIP factors"
			},
			{
				"name":"Cell cycle controlling factors, Myc"
			},
			{
				"name":"Cell cycle controlling factors, Mad\/Max"
			},
			{
				"name":"Other bHLH-ZIP factors"
			}
			]
		},
		{
			"name":"Other basic domains",
			"children":[
			{
				"name":"NF-1"
			},
			{
				"name":"RF-X"
			},
			{
				"name":"AP-2 (bHSH)"
			}
			]
		},
		{
			"name":"Zinc finger",
			"children":[
			{
				"name":"Cys4 thyroid hormone receptor-like"
			},
			{
				"name":"Cys4 hepatocyte nuclear factor 4-like"
			},
			{
				"name":"Cys4 estrogen receptor-like"
			},
			{
				"name":"Cys4 nerve growth factor IB-like"
			},
			{
				"name":"Cys4 Fushi tarazu-F1-like"
			},
			{
				"name":"Cys4 germ cell nuclear factor"
			},
			{
				"name":"Cys4 Knirps\/DAX1-like"
			},
			{
				"name":"Cys4 GATA-factors"
			},
			{
				"name":"Cys2His2 SP\/KLF family and related proteins"
			},
			{
				"name":"Cys2His2 GLI-like"
			},
			{
				"name":"Cys2His2 Snail"
			},
			{
				"name":"Cys2His2 BTB-ZF factors"
			},
			{
				"name":"Cys2His2 BED"
			},
			{
				"name":"Cys2His2 PRDM"
			},
			{
				"name":"Cys2His2 metabolic regulators in fungi"
			},
			{
				"name":"Cys2His2 others"
			},
			{
				"name":"Cys2HisCys zinc factors"
			},
			{
				"name":"Cys3His zinc factors"
			},
			{
				"name":"Cys2CysHis zinc factors"
			},
			{
				"name":"CXXC CpG-binding proteins"
			},
			{
				"name":"Cys6 metabolic regulators in fungi"
			},
			{
				"name":"Other zinc fingers"
			}
			]
		},
		{
			"name":"Helix-turn-helix",
			"children":[
			{
				"name":"Homeo domain ANTP: HOXL"
			},
			{
				"name":"Homeo domain ANTP: NKL"
			},
			{
				"name":"Homeo domain Paired-related"
			},
			{
				"name":"Homeo domain LIM"
			},
			{
				"name":"Homeo domain POU"
			},
			{
				"name":"Homeo domain SINE"
			},
			{
				"name":"Homeo domain ZF"
			},
			{
				"name":"Homeo domain CUT"
			},
			{
				"name":"Homeo domain PROS"
			},
			{
				"name":"Homeo domain TALE"
			},
			{
				"name":"Homeo domain other"
			},
			{
				"name":"Fork head\/winged helix developmental regulators"
			},
			{
				"name":"Fork head\/winged helix tissue-specific regulators"
			},
			{
				"name":"Fork head\/winged helix cell cycle-controlling factors, E2F"
			},
			{
				"name":"Fork head\/winged helix cell cycle-controlling factors, DP"
			},
			{
				"name":"Fork head\/winged helix other regulators"
			},
			{
				"name":"Stork head\/winged helix factors"
			},
			{
				"name":"Heat shock factors"
			},
			{
				"name":"Tryptophan clusters Myb, Myb-factors"
			},
			{
				"name":"Tryptophan clusters Myb, Myb-like factors"
			},
			{
				"name":"Tryptophan clusters Ets-type"
			},
			{
				"name":"Tryptophan clusters interferon-regulating factors"
			},
			{
				"name":"TEA domain"
			},
			{
				"name":"ARID"
			}
			]
		},
		{
			"name":"beta-Scaffold factors with minor groove contacts",
			"children":[
			{
				"name":"RHR (Rel homology region) Rel\/Ankyrin"
			},
			{
				"name":"RHR (Rel homology region) Ankyrin only"
			},
			{
				"name":"RHR (Rel homology region) NF-AT"
			},
			{
				"name":"STAT"
			},
			{
				"name":"p53"
			},
			{
				"name":"MADS-box regulators of differentiation, MEF-2"
			},
			{
				"name":"MADS-box regulators of differentiation, Homeotic genes"
			},
			{
				"name":"MADS-box regulators of differentiation, Yeast regulators"
			},
			{
				"name":"MADS-box responders to external signals"
			},
			{
				"name":"SAND domain-containing proteins"
			},
			{
				"name":"TATA-binding proteins"
			},
			{
				"name":"HMG SOX"
			},
			{
				"name":"HMG TCF-1"
			},
			{
				"name":"HMG TOX"
			},
			{
				"name":"HMG2-related"
			},
			{
				"name":"UBF"
			},
			{
				"name":"Other HMG box factors"
			},
			{
				"name":"Heteromeric CCAAT factors"
			},
			{
				"name":"Grainyhead"
			},
			{
				"name":"Cold-shock domain factors, DbpA-like"
			},
			{
				"name":"Cold-shock domain factors, YB-1\/DbpB-like"
			},
			{
				"name":"Cold-shock domain factors, FRG Y2-like"
			},
			{
				"name":"Runt"
			},
			{
				"name":"MYRF"
			}
			]
		},
		{
			"name":"Other transcription factors",
			"children":[
			{
				"name":"HMGI(Y)"
			},
			{
				"name":"NUPR"
			},
			{
				"name":"Pocket domain Rb"
			},
			{
				"name":"Pocket domain CBP"
			},
			{
				"name":"T-box"
			},
			{
				"name":"DMRT"
			},
			{
				"name":"LRRFIP"
			},
			{
				"name":"TCP"
			},
			{
				"name":"AP2\/ERF"
			},
			{
				"name":"WRKY"
			},
			{
				"name":"LOB"
			},
			{
				"name":"GRAS"
			},
			{
				"name":"NAC"
			},
			{
				"name":"Copper-fist proteins fungal regulators"
			},
			{
				"name":"Others"
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic type",
		"children":[
		{
			"name":"Helix-turn-helix",
			"children":[
			{
				"name":"AraC family"
			},
			{
				"name":"LysR family",
				"children":[
				{
					"name":"GT3921_12160 LysR family transcriptional regulator\tK09681 gltC; LysR family transcriptional regulator, transcription activator of glutamate synthase operon"
				},
				{
					"name":"GT3921_03950 LysR family transcriptional regulator\tK21755 bsdA; LysR family transcriptional regulator, salicylic acid-responsive activator of bsdBCD"
				},
				{
					"name":"GT3921_12310 LysR family transcriptional regulator\tK21900 cysL; LysR family transcriptional regulator, transcriptional activator of the cysJI operon"
				},
				{
					"name":"GT3921_15020 LysR family transcriptional regulator\tK21900 cysL; LysR family transcriptional regulator, transcriptional activator of the cysJI operon"
				},
				{
					"name":"GT3921_02915 LysR family transcriptional regulator\tK21960 ytlI; LysR family transcriptional regulator, regulator of the ytmI operon"
				}
				]
			},
			{
				"name":"DeoR family",
				"children":[
				{
					"name":"GT3921_10300 DeoR family transcriptional regulator\tK03436 fruR2; DeoR family transcriptional regulator, fructose operon transcriptional repressor"
				},
				{
					"name":"GT3921_02270 sporulation transcriptional regulator SpoIIID\tK06283 spoIIID; putative DeoR family transcriptional regulator, stage III sporulation protein D"
				},
				{
					"name":"GT3921_07050 transcriptional repressor CcpN\tK23774 ccpN; DeoR family transcriptional regulator, catabolite repression regulator"
				}
				]
			},
			{
				"name":"LacI family",
				"children":[
				{
					"name":"GT3921_02440 LacI family transcriptional regulator\tK02529 galR; LacI family transcriptional regulator, galactose operon repressor"
				},
				{
					"name":"GT3921_02700 transcriptional regulator\tK02529 galR; LacI family transcriptional regulator, galactose operon repressor"
				},
				{
					"name":"GT3921_05370 catabolite control protein A\tK02529 galR; LacI family transcriptional regulator, galactose operon repressor"
				},
				{
					"name":"GT3921_08760 LacI family transcriptional regulator\tK02529 galR; LacI family transcriptional regulator, galactose operon repressor"
				},
				{
					"name":"GT3921_09300 LacI family transcriptional regulator\tK02529 galR; LacI family transcriptional regulator, galactose operon repressor"
				},
				{
					"name":"GT3921_14770 LacI family transcriptional regulator\tK02529 galR; LacI family transcriptional regulator, galactose operon repressor"
				},
				{
					"name":"GT3921_09875 LacI family transcriptional regulator\tK02525 kdgR; LacI family transcriptional regulator, kdg operon repressor"
				},
				{
					"name":"GT3921_09000 LacI family transcriptional regulator\tK05499 cytR; LacI family transcriptional regulator, repressor for deo operon, udp, cdd, tsx, nupC, and nupG"
				}
				]
			},
			{
				"name":"GntR family",
				"children":[
				{
					"name":"GT3921_10830 trehalose operon repressor\tK03486 treR2; GntR family transcriptional regulator, trehalose operon transcriptional repressor"
				},
				{
					"name":"GT3921_08145 phosphonate metabolism transcriptional regulator PhnF\tK24967 nagR; GntR family transcriptional regulator, N-acetylglucosamine utilization regulator"
				},
				{
					"name":"GT3921_13110 GntR family transcriptional regulator\tK03710 K03710; GntR family transcriptional regulator"
				},
				{
					"name":"GT3921_17230 GntR family transcriptional regulator\tK05799 pdhR; GntR family transcriptional regulator, transcriptional repressor for pyruvate dehydrogenase complex"
				},
				{
					"name":"GT3921_15755 GntR family transcriptional regulator\tK00375 K00375; GntR family transcriptional regulator \/ MocR family aminotransferase"
				}
				]
			},
			{
				"name":"TetR\/AcrR family",
				"children":[
				{
					"name":"GT3921_05975 TetR family transcriptional regulator\tK13770 ysiA; TetR\/AcrR family transcriptional regulator, fatty acid metabolism regulator protein"
				}
				]
			},
			{
				"name":"Lrp\/AsnC family"
			},
			{
				"name":"LuxR family",
				"children":[
				{
					"name":"GT3921_06095 helix-turn-helix transcriptional regulator\tK01994 gerE; LuxR family transcriptional regulator, transcriptional regulator of spore coat protein"
				}
				]
			},
			{
				"name":"MarR family",
				"children":[
				{
					"name":"GT3921_16315 transcriptional regulator Hpr\tK09682 hpr; MarR family transcriptional regulator, protease production regulatory protein HPr"
				},
				{
					"name":"GT3921_14670 MarR family transcriptional regulator\tK15973 mhqR; MarR family transcriptional regulator, 2-MHQ and catechol-resistance regulon repressor"
				},
				{
					"name":"GT3921_10200 MarR family transcriptional regulator\tK23775 ohrR; MarR family transcriptional regulator, organic hydroperoxide resistance regulator"
				},
				{
					"name":"GT3921_11395 MarR family transcriptional regulator\tK23775 ohrR; MarR family transcriptional regulator, organic hydroperoxide resistance regulator"
				}
				]
			},
			{
				"name":"MerR family",
				"children":[
				{
					"name":"GT3921_12890 MerR family transcriptional regulator\tK03713 glnR; MerR family transcriptional regulator, glutamine synthetase repressor"
				},
				{
					"name":"GT3921_03615 Hg(II)-responsive transcriptional regulator\tK08365 merR; MerR family transcriptional regulator, mercuric resistance operon regulatory protein"
				},
				{
					"name":"GT3921_10815 MerR family transcriptional regulator\tK22491 litR; MerR family transcriptional regulator, light-induced transcriptional regulator"
				},
				{
					"name":"GT3921_10215 MerR family transcriptional regulator\tK23776 tnrA; MerR family transcriptional regulator, global nitrogen regulator"
				},
				{
					"name":"GT3921_17320 MerR family transcriptional regulator\tK21902 yfmP; MerR family transcriptional regulator, repressor of the yfmOP operon"
				}
				]
			},
			{
				"name":"Fur family",
				"children":[
				{
					"name":"GT3921_07910 transcriptional repressor\tK03711 fur; Fur family transcriptional regulator, ferric uptake regulator"
				},
				{
					"name":"GT3921_07130 transcriptional repressor\tK02076 zurR; Fur family transcriptional regulator, zinc uptake regulator"
				},
				{
					"name":"GT3921_16825 transcriptional repressor\tK09825 perR; Fur family transcriptional regulator, peroxide stress response regulator"
				}
				]
			},
			{
				"name":"IclR family",
				"children":[
				{
					"name":"GT3921_09710 IclR family transcriptional regulator\tK19333 kdgR; IclR family transcriptional regulator, KDG regulon repressor"
				},
				{
					"name":"GT3921_11720 IclR family transcriptional regulator\tK19333 kdgR; IclR family transcriptional regulator, KDG regulon repressor"
				}
				]
			},
			{
				"name":"CRP\/FNR family"
			},
			{
				"name":"Rrf2 family",
				"children":[
				{
					"name":"GT3921_10865 Rrf2 family transcriptional regulator\tK13771 nsrR; Rrf2 family transcriptional regulator, nitric oxide-sensitive transcriptional repressor"
				},
				{
					"name":"GT3921_06625 transcriptional regulator\tK17472 cymR; Rrf2 family transcriptional regulator, cysteine metabolism repressor"
				}
				]
			},
			{
				"name":"ArsR family",
				"children":[
				{
					"name":"GT3921_02740 transcriptional regulator\tK03892 arsR; ArsR family transcriptional regulator, arsenate\/arsenite\/antimonite-responsive transcriptional repressor"
				},
				{
					"name":"GT3921_08000 transcriptional regulator\tK21903 cadC; ArsR family transcriptional regulator, lead\/cadmium\/zinc\/bismuth-responsive transcriptional repressor"
				},
				{
					"name":"GT3921_15705 transcriptional regulator\tK21903 cadC; ArsR family transcriptional regulator, lead\/cadmium\/zinc\/bismuth-responsive transcriptional repressor"
				},
				{
					"name":"GT3921_12320 transcriptional regulator\tK22043 czrA; ArsR family transcriptional regulator, zinc-responsive transcriptional repressor"
				},
				{
					"name":"GT3921_08905 transcriptional regulator\tK26993 sdpR; ArsR family transcriptional regulator, repressor of sdpIR and other operons"
				}
				]
			},
			{
				"name":"XRE family"
			},
			{
				"name":"PadR family"
			},
			{
				"name":"Other families",
				"children":[
				{
					"name":"GT3921_07395 manganese transport transcriptional regulator\tK11924 mntR; DtxR family transcriptional regulator, manganese transport regulator"
				},
				{
					"name":"GT3921_08605 bifunctional biotin--[acetyl-CoA-carboxylase] synthetase\/biotin operon repressor\tK03524 birA; BirA family transcriptional regulator, biotin operon repressor \/ biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]"
				},
				{
					"name":"GT3921_05225 XRE family transcriptional regulator\tK20480 nprR; HTH-type transcriptional regulator, quorum sensing regulator NprR"
				},
				{
					"name":"GT3921_01200 pur operon repressor\tK09685 purR; HTH-type transcriptional regulator, purine operon repressor"
				},
				{
					"name":"GT3921_00480 sigma-54-dependent Fis family transcriptional regulator\tK06714 rocR; arginine utilization regulatory protein"
				},
				{
					"name":"GT3921_00105 redox-sensing transcriptional repressor Rex\tK01926 rex; redox-sensing transcriptional repressor"
				},
				{
					"name":"GT3921_18265 redox-sensing transcriptional repressor Rex\tK01926 rex; redox-sensing transcriptional repressor"
				},
				{
					"name":"GT3921_13445 transcriptional repressor CodY\tK03706 codY; transcriptional pleiotropic repressor"
				},
				{
					"name":"GT3921_00500 transcriptional regulator\tK07727 K07727; putative transcriptional regulator"
				},
				{
					"name":"GT3921_15850 transcriptional regulator\tK07729 K07729; putative transcriptional regulator"
				}
				]
			}
			]
		},
		{
			"name":"Ribbon-helix-helix",
			"children":[
			{
				"name":"CopG family",
				"children":[
				{
					"name":"GT3921_00255 antitoxin endoai\tK07723 ndoAI; CopG family transcriptional regulator \/ antitoxin EndoAI"
				}
				]
			},
			{
				"name":"Other families"
			}
			]
		},
		{
			"name":"Other transcription factors",
			"children":[
			{
				"name":"BglG family",
				"children":[
				{
					"name":"GT3921_09820 PTS sugar transporter\tK03483 mtlR; mannitol operon transcriptional activator"
				},
				{
					"name":"GT3921_01750 PTS sugar transporter\tK03491 licR; probable licABCH operon transcriptional regulator"
				}
				]
			},
			{
				"name":"Others",
				"children":[
				{
					"name":"GT3921_14965 transcriptional regulator\tK21600 csoR; CsoR family transcriptional regulator, copper-sensing transcriptional repressor"
				},
				{
					"name":"GT3921_12185 PucR family transcriptional regulator\tK09684 pucR; PucR family transcriptional regulator, purine catabolism regulatory protein"
				},
				{
					"name":"GT3921_01250 transition state regulator Abh\tK06284 abrB; AbrB family transcriptional regulator, transcriptional pleiotropic regulator of transition state genes"
				},
				{
					"name":"GT3921_04565 transition state regulator Abh\tK06284 abrB; AbrB family transcriptional regulator, transcriptional pleiotropic regulator of transition state genes"
				},
				{
					"name":"GT3921_01155 stage V sporulation protein T\tK04769 spoVT; AbrB family transcriptional regulator, stage V sporulation protein T"
				},
				{
					"name":"GT3921_01500 nucleoid occlusion protein\tK03497 parB; ParB family transcriptional regulator, chromosome partitioning protein"
				},
				{
					"name":"GT3921_01515 chromosome partitioning protein ParB\tK03497 parB; ParB family transcriptional regulator, chromosome partitioning protein"
				},
				{
					"name":"GT3921_08725 glycerol-3-phosphate responsive antiterminator GlpP\tK02443 glpP; glycerol uptake operon antiterminator"
				},
				{
					"name":"GT3921_07525 arginine repressor\tK03402 argR; transcriptional regulator of arginine metabolism"
				},
				{
					"name":"GT3921_06945 heat-inducible transcriptional repressor HrcA\tK03705 hrcA; heat-inducible transcriptional repressor"
				},
				{
					"name":"GT3921_16505 thiaminase II\tK03707 tenA; thiaminase (transcriptional activator TenA) [EC:3.5.99.2]"
				},
				{
					"name":"GT3921_16485 thiamine phosphate synthase\tK10810 tenI; thiazole tautomerase (transcriptional regulator TenI) [EC:5.3.99.10]"
				},
				{
					"name":"GT3921_00955 CtsR family transcriptional regulator\tK03708 ctsR; transcriptional regulator of stress and heat shock response"
				},
				{
					"name":"GT3921_09405 phenylacetic acid degradation operon negative regulatory protein PaaX\tK02616 paaX; phenylacetic acid degradation operon negative regulatory protein"
				},
				{
					"name":"GT3921_03815 hypothetical protein\tK05311 cggR; central glycolytic genes regulator"
				},
				{
					"name":"GT3921_08440 transcription attenuation protein MtrB\tK06285 mtrB; transcription attenuation protein (tryptophan RNA-binding attenuator protein)"
				},
				{
					"name":"GT3921_13765 bifunctional pyr operon transcriptional regulator\/uracil phosphoribosyltransferase\tK02825 pyrR; pyrimidine operon attenuation protein \/ uracil phosphoribosyltransferase [EC:2.4.2.9]"
				},
				{
					"name":"GT3921_01900 transcriptional regulator\tK06314 rsfA; prespore-specific regulator"
				},
				{
					"name":"GT3921_06600 transcriptional regulator\tK06314 rsfA; prespore-specific regulator"
				},
				{
					"name":"GT3921_15750 transcriptional regulator\tK07734 paiB; transcriptional regulator"
				},
				{
					"name":"GT3921_05810 transcriptional regulator NrdR\tK07738 nrdR; transcriptional repressor NrdR"
				},
				{
					"name":"GT3921_17280 transcriptional regulator\tK09683 hutP; hut operon positive regulatory protein"
				},
				{
					"name":"GT3921_16185 competence protein ComK\tK02250 comK; competence protein ComK"
				}
				]
			}
			]
		}
		]
	}
	]
}