{ "name":"gvr03041", "children":[ { "name":"Common components", "children":[ { "name":"Common spliceosomal components", "children":[ { "name":"Cap binding complex", "children":[ { "name":"103608446 NCBP2; nuclear cap-binding protein subunit 2\tK12883 NCBP2; nuclear cap-binding protein subunit 2" } ] }, { "name":"hnRNP proteins", "children":[ { "name":"103583940 LOW QUALITY PROTEIN: heterogeneous nuclear ribonucleoprotein A1-like\tK12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1\/A3" }, { "name":"103584695 LOW QUALITY PROTEIN: heterogeneous nuclear ribonucleoprotein A3-like\tK12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1\/A3" }, { "name":"103591062 HNRNPA3; heterogeneous nuclear ribonucleoprotein A3 isoform X1\tK12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1\/A3" }, { "name":"103593247 HNRNPA1; heterogeneous nuclear ribonucleoprotein A1 isoform X1\tK12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1\/A3" }, { "name":"103599759 heterogeneous nuclear ribonucleoprotein A1-like\tK12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1\/A3" }, { "name":"103604000 heterogeneous nuclear ribonucleoprotein A1-like\tK12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1\/A3" }, { "name":"103604411 LOW QUALITY PROTEIN: heterogeneous nuclear ribonucleoprotein A1-like\tK12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1\/A3" }, { "name":"103606742 heterogeneous nuclear ribonucleoprotein A1-like\tK12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1\/A3" }, { "name":"103591594 HNRNPC; heterogeneous nuclear ribonucleoproteins C1\/C2\tK12884 HNRNPC; heterogeneous nuclear ribonucleoprotein C1\/C2" }, { "name":"103603442 heterogeneous nuclear ribonucleoprotein C\tK12884 HNRNPC; heterogeneous nuclear ribonucleoprotein C1\/C2" }, { "name":"103601066 RBMX; RNA-binding motif protein, X chromosome\tK12885 RBMX; heterogeneous nuclear ribonucleoprotein G" }, { "name":"103587550 HNRNPK; heterogeneous nuclear ribonucleoprotein K\tK12886 HNRNPK; heterogeneous nuclear ribonucleoprotein K" }, { "name":"103599765 HNRNPM; heterogeneous nuclear ribonucleoprotein M isoform X1\tK12887 HNRNPM; heterogeneous nuclear ribonucleoprotein M" }, { "name":"103605516 HNRNPU; heterogeneous nuclear ribonucleoprotein U isoform X1\tK12888 HNRNPU; heterogeneous nuclear ribonucleoprotein U" }, { "name":"103583217 poly(rC)-binding protein 1-like isoform X1\tK12889 PCBP1; poly(rC)-binding protein 1" }, { "name":"103593226 PCBP1; poly(rC)-binding protein 1\tK12889 PCBP1; poly(rC)-binding protein 1" }, { "name":"103600889 LOW QUALITY PROTEIN: poly(rC)-binding protein 1-like\tK12889 PCBP1; poly(rC)-binding protein 1" }, { "name":"103606271 poly(rC)-binding protein 1-like\tK12889 PCBP1; poly(rC)-binding protein 1" } ] }, { "name":"SR proteins", "children":[ { "name":"103604343 SRSF1; serine\/arginine-rich splicing factor 1\tK12890 SRSF1; serine\/arginine-rich splicing factor 1" }, { "name":"103584271 serine\/arginine-rich splicing factor 2-like\tK12891 SRSF2_8; serine\/arginine-rich splicing factor 2\/8" }, { "name":"103605220 SRSF2; serine\/arginine-rich splicing factor 2\tK12891 SRSF2_8; serine\/arginine-rich splicing factor 2\/8" }, { "name":"103607324 SRSF3; serine\/arginine-rich splicing factor 3\tK12892 SRSF3; serine\/arginine-rich splicing factor 3" }, { "name":"103587223 SRSF4; serine\/arginine-rich splicing factor 4\tK12893 SRSF4_5_6; serine\/arginine-rich splicing factor 4\/5\/6" }, { "name":"103601016 SRSF5; serine\/arginine-rich splicing factor 5 isoform X1\tK12893 SRSF4_5_6; serine\/arginine-rich splicing factor 4\/5\/6" }, { "name":"103607382 SRSF6; serine\/arginine-rich splicing factor 6\tK12893 SRSF4_5_6; serine\/arginine-rich splicing factor 4\/5\/6" }, { "name":"103592531 SRSF7; serine\/arginine-rich splicing factor 7 isoform X1\tK12896 SRSF7; serine\/arginine-rich splicing factor 7" }, { "name":"103587797 SRSF9; serine\/arginine-rich splicing factor 9\tK21123 SRSF9; serine\/arginine-rich splicing factor 9" }, { "name":"103590796 SRSF10; serine\/arginine-rich splicing factor 10 isoform X1\tK12900 SRSF10; serine\/arginine-rich splicing factor 10" }, { "name":"103585538 transformer-2 protein homolog alpha isoform X1\tK12897 TRA2; transformer-2 protein" }, { "name":"103594637 TRA2B; transformer-2 protein homolog beta isoform X1\tK12897 TRA2; transformer-2 protein" } ] }, { "name":"General mRNP proteins", "children":[ { "name":"103592301 BCLAF1; bcl-2-associated transcription factor 1 isoform X1\tK13087 BCLAF1; bcl2 associated transcription factor 1" }, { "name":"103581891 ELAV-like protein 1\tK13088 ELAVL1; ELAV-like protein 1" }, { "name":"103596398 ELAVL1; ELAV-like protein 1\tK13088 ELAVL1; ELAV-like protein 1" }, { "name":"103586357 ILF2; interleukin enhancer-binding factor 2\tK13089 ILF2; interleukin enhancer-binding factor 2" }, { "name":"103611051 ILF3; interleukin enhancer-binding factor 3 isoform X2\tK13090 ILF3; interleukin enhancer-binding factor 3" }, { "name":"103585557 RBM23; probable RNA-binding protein 23 isoform X1\tK13091 RBM23_39; RNA-binding protein 23\/39" }, { "name":"103587901 RBM39; LOW QUALITY PROTEIN: RNA-binding protein 39\tK13091 RBM23_39; RNA-binding protein 23\/39" }, { "name":"103590834 YBX1; nuclease-sensitive element-binding protein 1\tK09276 YBX1; Y-box-binding protein 1" }, { "name":"103585021 ZC3H18; zinc finger CCCH domain-containing protein 18\tK13092 ZC3H18; nuclear protein NHN1" } ] } ] } ] }, { "name":"Complex A", "children":[ { "name":"U1 snRNP components", "children":[ { "name":"Sm proteins", "children":[ { "name":"103610529 SNRPB; small nuclear ribonucleoprotein-associated proteins B and B' isoform X1\tK11086 SNRPB; small nuclear ribonucleoprotein B and B'" }, { "name":"103595028 LOW QUALITY PROTEIN: small nuclear ribonucleoprotein Sm D1-like\tK11087 SNRPD1; small nuclear ribonucleoprotein D1" }, { "name":"103603927 SNRPD1; small nuclear ribonucleoprotein Sm D1\tK11087 SNRPD1; small nuclear ribonucleoprotein D1" }, { "name":"103595246 SNRPD2; small nuclear ribonucleoprotein Sm D2\tK11096 SNRPD2; small nuclear ribonucleoprotein D2" }, { "name":"103609772 SNRPD3; small nuclear ribonucleoprotein Sm D3\tK11088 SNRPD3; small nuclear ribonucleoprotein D3" }, { "name":"103607790 SNRPE; small nuclear ribonucleoprotein E\tK11097 SNRPE; small nuclear ribonucleoprotein E" }, { "name":"103593289 small nuclear ribonucleoprotein F-like\tK11098 SNRPF; small nuclear ribonucleoprotein F" }, { "name":"103593751 SNRPF; small nuclear ribonucleoprotein F\tK11098 SNRPF; small nuclear ribonucleoprotein F" }, { "name":"103593229 SNRPG; small nuclear ribonucleoprotein G\tK11099 SNRPG; small nuclear ribonucleoprotein G" } ] }, { "name":"U1 snRNP specific factors", "children":[ { "name":"103587767 SNRNP70; U1 small nuclear ribonucleoprotein 70 kDa isoform X1\tK11093 SNRP70; U1 small nuclear ribonucleoprotein 70kDa" }, { "name":"103603549 SNRPA; U1 small nuclear ribonucleoprotein A\tK11091 SNRPA; U1 small nuclear ribonucleoprotein A" }, { "name":"103610479 LOW QUALITY PROTEIN: U1 small nuclear ribonucleoprotein C-like\tK11095 SNRPC; U1 small nuclear ribonucleoprotein C" } ] }, { "name":"U1 related factors", "children":[ { "name":"103593819 DDX5; probable ATP-dependent RNA helicase DDX5\tK12823 DDX5; ATP-dependent RNA helicase DDX5\/DBP2 [EC:5.6.2.7]" }, { "name":"103593263 PRPF40A; pre-mRNA-processing factor 40 homolog A isoform X1\tK12821 PRPF40; pre-mRNA-processing factor 40" }, { "name":"103598713 PRPF40B; pre-mRNA-processing factor 40 homolog B isoform X1\tK12821 PRPF40; pre-mRNA-processing factor 40" }, { "name":"103599713 RBM25; RNA-binding protein 25\tK12822 RBM25; RNA-binding protein 25" }, { "name":"103587572 TCERG1; transcription elongation regulator 1 isoform X1\tK12824 TCERG1; transcription elongation regulator 1" } ] } ] }, { "name":"U2 snRNP components", "children":[ { "name":"Sm proteins", "children":[ { "name":"103610529 SNRPB; small nuclear ribonucleoprotein-associated proteins B and B' isoform X1\tK11086 SNRPB; small nuclear ribonucleoprotein B and B'" }, { "name":"103595028 LOW QUALITY PROTEIN: small nuclear ribonucleoprotein Sm D1-like\tK11087 SNRPD1; small nuclear ribonucleoprotein D1" }, { "name":"103603927 SNRPD1; small nuclear ribonucleoprotein Sm D1\tK11087 SNRPD1; small nuclear ribonucleoprotein D1" }, { "name":"103595246 SNRPD2; small nuclear ribonucleoprotein Sm D2\tK11096 SNRPD2; small nuclear ribonucleoprotein D2" }, { "name":"103609772 SNRPD3; small nuclear ribonucleoprotein Sm D3\tK11088 SNRPD3; small nuclear ribonucleoprotein D3" }, { "name":"103607790 SNRPE; small nuclear ribonucleoprotein E\tK11097 SNRPE; small nuclear ribonucleoprotein E" }, { "name":"103593289 small nuclear ribonucleoprotein F-like\tK11098 SNRPF; small nuclear ribonucleoprotein F" }, { "name":"103593751 SNRPF; small nuclear ribonucleoprotein F\tK11098 SNRPF; small nuclear ribonucleoprotein F" }, { "name":"103593229 SNRPG; small nuclear ribonucleoprotein G\tK11099 SNRPG; small nuclear ribonucleoprotein G" } ] }, { "name":"U2 snRNP specific factors", "children":[ { "name":"103589157 SNRPA1; U2 small nuclear ribonucleoprotein A'\tK11092 SNRPA1; U2 small nuclear ribonucleoprotein A'" }, { "name":"103591996 SNRPB2; U2 small nuclear ribonucleoprotein B''\tK11094 SNRPB2; U2 small nuclear ribonucleoprotein B''" }, { "name":"103589400 SF3A1; splicing factor 3A subunit 1\tK12825 SF3A1; splicing factor 3A subunit 1" }, { "name":"103601163 SF3A2; splicing factor 3A subunit 2\tK12826 SF3A2; splicing factor 3A subunit 2" }, { "name":"103587874 SF3A3; splicing factor 3A subunit 3\tK12827 SF3A3; splicing factor 3A subunit 3" }, { "name":"103587113 SF3B1; splicing factor 3B subunit 1 isoform X1\tK12828 SF3B1; splicing factor 3B subunit 1" }, { "name":"103608191 SF3B2; splicing factor 3B subunit 2\tK12829 SF3B2; splicing factor 3B subunit 2" }, { "name":"103598315 SF3B3; splicing factor 3B subunit 3\tK12830 SF3B3; splicing factor 3B subunit 3" }, { "name":"103601195 SF3B4; splicing factor 3B subunit 4\tK12831 SF3B4; splicing factor 3B subunit 4" }, { "name":"103600556 SF3B5; splicing factor 3B subunit 5\tK12832 SF3B5; splicing factor 3B subunit 5" }, { "name":"103604536 SF3B6; splicing factor 3B subunit 6\tK12833 SF3B14; pre-mRNA branch site protein p14" }, { "name":"103595640 DDX42; ATP-dependent RNA helicase DDX42 isoform X1\tK12835 DDX42; ATP-dependent RNA helicase DDX42 [EC:5.6.2.7]" }, { "name":"103591644 PHF5A; PHD finger-like domain-containing protein 5A\tK12834 PHF5A; PHD finger-like domain-containing protein 5A" } ] }, { "name":"U2 related factors", "children":[ { "name":"103581265 splicing factor U2AF 35 kDa subunit\tK12836 U2AF1; splicing factor U2AF 35 kDa subunit" }, { "name":"103592825 U2AF1L4; splicing factor U2AF 26 kDa subunit isoform X1\tK12836 U2AF1; splicing factor U2AF 35 kDa subunit" }, { "name":"103598233 U2AF2; splicing factor U2AF 65 kDa subunit isoform X1\tK12837 U2AF2; splicing factor U2AF 65 kDa subunit" }, { "name":"103598938 CHERP; calcium homeostasis endoplasmic reticulum protein isoform X1\tK12841 CHERP; calcium homeostasis endoplasmic reticulum protein" }, { "name":"103598229 DHX15; putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15\tK12820 DHX15; pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15\/PRP43 [EC:5.6.2.6]" }, { "name":"103591159 DDX46; probable ATP-dependent RNA helicase DDX46 isoform X1\tK12811 DDX46; ATP-dependent RNA helicase DDX46\/PRP5 [EC:5.6.2.7]" }, { "name":"103589640 PUF60; poly(U)-binding-splicing factor PUF60 isoform X1\tK12838 PUF60; poly(U)-binding-splicing factor PUF60" }, { "name":"103606506 RBM17; splicing factor 45\tK12840 RBM17; splicing factor 45" }, { "name":"103588289 SMNDC1; survival of motor neuron-related-splicing factor 30 isoform X1\tK12839 SMNDC1; survival of motor neuron-related-splicing factor 30" }, { "name":"103602528 U2SURP; U2 snRNP-associated SURP motif-containing protein isoform X1\tK12842 SR140; U2-associated protein SR140" }, { "name":"103582555 LOW QUALITY PROTEIN: retinitis pigmentosa 9 protein-like\tK19604 RP9; retinitis pigmentosa 9 protein" }, { "name":"103594678 LOW QUALITY PROTEIN: U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2-like\tK24273 ZRSR; U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein" }, { "name":"103599115 LOW QUALITY PROTEIN: U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2-like\tK24273 ZRSR; U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein" } ] } ] }, { "name":"Other components", "children":[ { "name":"Complex A specific factors", "children":[ { "name":"103595986 BUB3; mitotic checkpoint protein BUB3 isoform X1\tK02180 BUB3; cell cycle arrest protein BUB3" }, { "name":"103599718 cyclin-dependent kinase 11B isoform X1\tK08818 CDC2L; cell division cycle 2-like [EC:2.7.11.22]" }, { "name":"103584160 HIV Tat-specific factor 1-like\tK13093 HTATSF1; HIV Tat-specific factor 1" }, { "name":"103602342 HIV Tat-specific factor 1 homolog\tK13093 HTATSF1; HIV Tat-specific factor 1" }, { "name":"103584894 RBM5; RNA-binding protein 5\tK13094 RBM5_10; RNA-binding protein 5\/10" }, { "name":"103592333 RBM10; RNA-binding protein 10 isoform X1\tK13094 RBM5_10; RNA-binding protein 5\/10" }, { "name":"103590609 SF1; splicing factor 1 isoform X1\tK13095 SF1; splicing factor 1" }, { "name":"103588123 SUGP1; SURP and G-patch domain-containing protein 1\tK13096 SF4; splicing factor 4" }, { "name":"103585990 TET1; methylcytosine dioxygenase TET1\tK13097 TET1; methylcytosine dioxygenase [EC:1.14.11.80]" }, { "name":"103610076 FUS; RNA-binding protein FUS isoform X1\tK13098 TLS; RNA-binding protein FUS" }, { "name":"103587669 RBM20; RNA-binding protein 20\tK24052 RBM20; RNA-binding protein 20" } ] } ] } ] }, { "name":"Complex B", "children":[ { "name":"U1 snRNP components", "children":[ { "name":"Sm proteins", "children":[ { "name":"103610529 SNRPB; small nuclear ribonucleoprotein-associated proteins B and B' isoform X1\tK11086 SNRPB; small nuclear ribonucleoprotein B and B'" }, { "name":"103595028 LOW QUALITY PROTEIN: small nuclear ribonucleoprotein Sm D1-like\tK11087 SNRPD1; small nuclear ribonucleoprotein D1" }, { "name":"103603927 SNRPD1; small nuclear ribonucleoprotein Sm D1\tK11087 SNRPD1; small nuclear ribonucleoprotein D1" }, { "name":"103595246 SNRPD2; small nuclear ribonucleoprotein Sm D2\tK11096 SNRPD2; small nuclear ribonucleoprotein D2" }, { "name":"103609772 SNRPD3; small nuclear ribonucleoprotein Sm D3\tK11088 SNRPD3; small nuclear ribonucleoprotein D3" }, { "name":"103607790 SNRPE; small nuclear ribonucleoprotein E\tK11097 SNRPE; small nuclear ribonucleoprotein E" }, { "name":"103593289 small nuclear ribonucleoprotein F-like\tK11098 SNRPF; small nuclear ribonucleoprotein F" }, { "name":"103593751 SNRPF; small nuclear ribonucleoprotein F\tK11098 SNRPF; small nuclear ribonucleoprotein F" }, { "name":"103593229 SNRPG; small nuclear ribonucleoprotein G\tK11099 SNRPG; small nuclear ribonucleoprotein G" } ] }, { "name":"U1 snRNP specific factors", "children":[ { "name":"103587767 SNRNP70; U1 small nuclear ribonucleoprotein 70 kDa isoform X1\tK11093 SNRP70; U1 small nuclear ribonucleoprotein 70kDa" }, { "name":"103603549 SNRPA; U1 small nuclear ribonucleoprotein A\tK11091 SNRPA; U1 small nuclear ribonucleoprotein A" }, { "name":"103610479 LOW QUALITY PROTEIN: U1 small nuclear ribonucleoprotein C-like\tK11095 SNRPC; U1 small nuclear ribonucleoprotein C" } ] }, { "name":"U1 related factors", "children":[ { "name":"103593819 DDX5; probable ATP-dependent RNA helicase DDX5\tK12823 DDX5; ATP-dependent RNA helicase DDX5\/DBP2 [EC:5.6.2.7]" }, { "name":"103593263 PRPF40A; pre-mRNA-processing factor 40 homolog A isoform X1\tK12821 PRPF40; pre-mRNA-processing factor 40" }, { "name":"103598713 PRPF40B; pre-mRNA-processing factor 40 homolog B isoform X1\tK12821 PRPF40; pre-mRNA-processing factor 40" }, { "name":"103599713 RBM25; RNA-binding protein 25\tK12822 RBM25; RNA-binding protein 25" }, { "name":"103587572 TCERG1; transcription elongation regulator 1 isoform X1\tK12824 TCERG1; transcription elongation regulator 1" } ] } ] }, { "name":"U2 snRNP components", "children":[ { "name":"Sm proteins", "children":[ { "name":"103610529 SNRPB; small nuclear ribonucleoprotein-associated proteins B and B' isoform X1\tK11086 SNRPB; small nuclear ribonucleoprotein B and B'" }, { "name":"103595028 LOW QUALITY PROTEIN: small nuclear ribonucleoprotein Sm D1-like\tK11087 SNRPD1; small nuclear ribonucleoprotein D1" }, { "name":"103603927 SNRPD1; small nuclear ribonucleoprotein Sm D1\tK11087 SNRPD1; small nuclear ribonucleoprotein D1" }, { "name":"103595246 SNRPD2; small nuclear ribonucleoprotein Sm D2\tK11096 SNRPD2; small nuclear ribonucleoprotein D2" }, { "name":"103609772 SNRPD3; small nuclear ribonucleoprotein Sm D3\tK11088 SNRPD3; small nuclear ribonucleoprotein D3" }, { "name":"103607790 SNRPE; small nuclear ribonucleoprotein E\tK11097 SNRPE; small nuclear ribonucleoprotein E" }, { "name":"103593289 small nuclear ribonucleoprotein F-like\tK11098 SNRPF; small nuclear ribonucleoprotein F" }, { "name":"103593751 SNRPF; small nuclear ribonucleoprotein F\tK11098 SNRPF; small nuclear ribonucleoprotein F" }, { "name":"103593229 SNRPG; small nuclear ribonucleoprotein G\tK11099 SNRPG; small nuclear ribonucleoprotein G" } ] }, { "name":"U2 snRNP specific factors", "children":[ { "name":"103589157 SNRPA1; U2 small nuclear ribonucleoprotein A'\tK11092 SNRPA1; U2 small nuclear ribonucleoprotein A'" }, { "name":"103591996 SNRPB2; U2 small nuclear ribonucleoprotein B''\tK11094 SNRPB2; U2 small nuclear ribonucleoprotein B''" }, { "name":"103589400 SF3A1; splicing factor 3A subunit 1\tK12825 SF3A1; splicing factor 3A subunit 1" }, { "name":"103601163 SF3A2; splicing factor 3A subunit 2\tK12826 SF3A2; splicing factor 3A subunit 2" }, { "name":"103587874 SF3A3; splicing factor 3A subunit 3\tK12827 SF3A3; splicing factor 3A subunit 3" }, { "name":"103587113 SF3B1; splicing factor 3B subunit 1 isoform X1\tK12828 SF3B1; splicing factor 3B subunit 1" }, { "name":"103608191 SF3B2; splicing factor 3B subunit 2\tK12829 SF3B2; splicing factor 3B subunit 2" }, { "name":"103598315 SF3B3; splicing factor 3B subunit 3\tK12830 SF3B3; splicing factor 3B subunit 3" }, { "name":"103601195 SF3B4; splicing factor 3B subunit 4\tK12831 SF3B4; splicing factor 3B subunit 4" }, { "name":"103600556 SF3B5; splicing factor 3B subunit 5\tK12832 SF3B5; splicing factor 3B subunit 5" }, { "name":"103604536 SF3B6; splicing factor 3B subunit 6\tK12833 SF3B14; pre-mRNA branch site protein p14" }, { "name":"103595640 DDX42; ATP-dependent RNA helicase DDX42 isoform X1\tK12835 DDX42; ATP-dependent RNA helicase DDX42 [EC:5.6.2.7]" }, { "name":"103591644 PHF5A; PHD finger-like domain-containing protein 5A\tK12834 PHF5A; PHD finger-like domain-containing protein 5A" } ] }, { "name":"U2 related factors", "children":[ { "name":"103581265 splicing factor U2AF 35 kDa subunit\tK12836 U2AF1; splicing factor U2AF 35 kDa subunit" }, { "name":"103592825 U2AF1L4; splicing factor U2AF 26 kDa subunit isoform X1\tK12836 U2AF1; splicing factor U2AF 35 kDa subunit" }, { "name":"103598233 U2AF2; splicing factor U2AF 65 kDa subunit isoform X1\tK12837 U2AF2; splicing factor U2AF 65 kDa subunit" }, { "name":"103598938 CHERP; calcium homeostasis endoplasmic reticulum protein isoform X1\tK12841 CHERP; calcium homeostasis endoplasmic reticulum protein" }, { "name":"103598229 DHX15; putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15\tK12820 DHX15; pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15\/PRP43 [EC:5.6.2.6]" }, { "name":"103591159 DDX46; probable ATP-dependent RNA helicase DDX46 isoform X1\tK12811 DDX46; ATP-dependent RNA helicase DDX46\/PRP5 [EC:5.6.2.7]" }, { "name":"103589640 PUF60; poly(U)-binding-splicing factor PUF60 isoform X1\tK12838 PUF60; poly(U)-binding-splicing factor PUF60" }, { "name":"103606506 RBM17; splicing factor 45\tK12840 RBM17; splicing factor 45" }, { "name":"103588289 SMNDC1; survival of motor neuron-related-splicing factor 30 isoform X1\tK12839 SMNDC1; survival of motor neuron-related-splicing factor 30" }, { "name":"103602528 U2SURP; U2 snRNP-associated SURP motif-containing protein isoform X1\tK12842 SR140; U2-associated protein SR140" }, { "name":"103582555 LOW QUALITY PROTEIN: retinitis pigmentosa 9 protein-like\tK19604 RP9; retinitis pigmentosa 9 protein" }, { "name":"103594678 LOW QUALITY PROTEIN: U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2-like\tK24273 ZRSR; U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein" }, { "name":"103599115 LOW QUALITY PROTEIN: U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2-like\tK24273 ZRSR; U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein" } ] } ] }, { "name":"U4\/U6.U5 tri-snRNP components", "children":[ { "name":"Sm proteins", "children":[ { "name":"103610529 SNRPB; small nuclear ribonucleoprotein-associated proteins B and B' isoform X1\tK11086 SNRPB; small nuclear ribonucleoprotein B and B'" }, { "name":"103595028 LOW QUALITY PROTEIN: small nuclear ribonucleoprotein Sm D1-like\tK11087 SNRPD1; small nuclear ribonucleoprotein D1" }, { "name":"103603927 SNRPD1; small nuclear ribonucleoprotein Sm D1\tK11087 SNRPD1; small nuclear ribonucleoprotein D1" }, { "name":"103595246 SNRPD2; small nuclear ribonucleoprotein Sm D2\tK11096 SNRPD2; small nuclear ribonucleoprotein D2" }, { "name":"103609772 SNRPD3; small nuclear ribonucleoprotein Sm D3\tK11088 SNRPD3; small nuclear ribonucleoprotein D3" }, { "name":"103607790 SNRPE; small nuclear ribonucleoprotein E\tK11097 SNRPE; small nuclear ribonucleoprotein E" }, { "name":"103593289 small nuclear ribonucleoprotein F-like\tK11098 SNRPF; small nuclear ribonucleoprotein F" }, { "name":"103593751 SNRPF; small nuclear ribonucleoprotein F\tK11098 SNRPF; small nuclear ribonucleoprotein F" }, { "name":"103593229 SNRPG; small nuclear ribonucleoprotein G\tK11099 SNRPG; small nuclear ribonucleoprotein G" } ] }, { "name":"LSm proteins", "children":[ { "name":"103592386 LSM2; U6 snRNA-associated Sm-like protein LSm2\tK12621 LSM2; U6 snRNA-associated Sm-like protein LSm2" }, { "name":"103604629 LSM3; U6 snRNA-associated Sm-like protein LSm3\tK12622 LSM3; U6 snRNA-associated Sm-like protein LSm3" }, { "name":"103608690 LSM4; U6 snRNA-associated Sm-like protein LSm4 isoform X1\tK12623 LSM4; U6 snRNA-associated Sm-like protein LSm4" }, { "name":"103590244 LSM5; U6 snRNA-associated Sm-like protein LSm5 isoform X1\tK12624 LSM5; U6 snRNA-associated Sm-like protein LSm5" }, { "name":"103604676 LSM6; U6 snRNA-associated Sm-like protein LSm6 isoform X1\tK12625 LSM6; U6 snRNA-associated Sm-like protein LSm6" }, { "name":"103586886 LSM8; LSM8 homolog, U6 small nuclear RNA associated\tK12627 LSM8; U6 snRNA-associated Sm-like protein LSm8" } ] }, { "name":"U4\/U6 snRNP specific factors", "children":[ { "name":"103600430 PRPF3; U4\/U6 small nuclear ribonucleoprotein Prp3\tK12843 PRPF3; U4\/U6 small nuclear ribonucleoprotein PRP3" }, { "name":"103587276 PRPF4; U4\/U6 small nuclear ribonucleoprotein Prp4\tK12662 PRPF4; U4\/U6 small nuclear ribonucleoprotein PRP4" }, { "name":"103590830 PPIH; peptidyl-prolyl cis-trans isomerase H\tK09567 PPIH; peptidyl-prolyl isomerase H (cyclophilin H) [EC:5.2.1.8]" }, { "name":"103606872 PRPF31; U4\/U6 small nuclear ribonucleoprotein Prp31\tK12844 PRPF31; U4\/U6 small nuclear ribonucleoprotein PRP31" }, { "name":"103584091 NHP2L1; NHP2-like protein 1\tK12845 SNU13; U4\/U6 small nuclear ribonucleoprotein SNU13" }, { "name":"103597278 SART3; squamous cell carcinoma antigen recognized by T-cells 3\tK22611 SART3; spliceosome associated factor 3, U4\/U6 recycling protein" } ] }, { "name":"U5 snRNP specific factors", "children":[ { "name":"103595006 EFTUD2; 116 kDa U5 small nuclear ribonucleoprotein component\tK12852 EFTUD2; 116 kDa U5 small nuclear ribonucleoprotein component" }, { "name":"103593792 PRPF6; pre-mRNA-processing factor 6 isoform X1\tK12855 PRPF6; pre-mRNA-processing factor 6" }, { "name":"103584891 PRPF8; pre-mRNA-processing-splicing factor 8\tK12856 PRPF8; pre-mRNA-processing factor 8" }, { "name":"103597089 SNRNP40; U5 small nuclear ribonucleoprotein 40 kDa protein\tK12857 SNRNP40; Prp8 binding protein" }, { "name":"103586607 SNRNP200; U5 small nuclear ribonucleoprotein 200 kDa helicase\tK12854 SNRNP200; pre-mRNA-splicing helicase BRR2 [EC:5.6.2.6]" }, { "name":"103588861 DDX23; probable ATP-dependent RNA helicase DDX23\tK12858 DDX23; ATP-dependent RNA helicase DDX23\/PRP28 [EC:5.6.2.7]" }, { "name":"103599486 TXNL4A; thioredoxin-like protein 4A\tK12859 TXNL4A; U5 snRNP protein, DIM1 family" }, { "name":"103609529 CD2BP2; CD2 antigen cytoplasmic tail-binding protein 2\tK13099 CD2BP2; CD2 antigen cytoplasmic tail-binding protein 2" } ] }, { "name":"U4\/U6.U5 tri-snRNP specific factors", "children":[ { "name":"103605624 SART1; U4\/U6.U5 tri-snRNP-associated protein 1\tK11984 SART1; U4\/U6.U5 tri-snRNP-associated protein 1" }, { "name":"103594520 USP39; U4\/U6.U5 tri-snRNP-associated protein 2\tK12847 USP39; U4\/U6.U5 tri-snRNP-associated protein 2" }, { "name":"103593221 SNRNP27; U4\/U6.U5 small nuclear ribonucleoprotein 27 kDa protein\tK12846 SNRNP27; U4\/U6.U5 tri-snRNP-associated protein 3" } ] }, { "name":"U4\/U6.U5 tri-snRNP related factors", "children":[ { "name":"103601360 ZMAT2; zinc finger matrin-type protein 2\tK12848 SNU23; U4\/U6.U5 tri-snRNP component SNU23" }, { "name":"103594887 PRPF38A; pre-mRNA-splicing factor 38A\tK12849 PRPF38A; pre-mRNA-splicing factor 38A" }, { "name":"103585330 PRPF38B; pre-mRNA-splicing factor 38B\tK12850 PRPF38B; pre-mRNA-splicing factor 38B" }, { "name":"103589119 CWC22; pre-mRNA-splicing factor CWC22 homolog\tK13100 CWC22; pre-mRNA-splicing factor CWC22" }, { "name":"103590787 SKIV2L2; superkiller viralicidic activity 2-like 2\tK12598 MTR4; ATP-dependent RNA helicase DOB1 [EC:5.6.2.6]" }, { "name":"103592546 DHX16; putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16\tK12813 DHX16; pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 [EC:5.6.2.6]" }, { "name":"103602705 GPKOW; G patch domain and KOW motifs-containing protein\tK13101 GPKOW; G patch domain and KOW motifs-containing protein" }, { "name":"103610401 HSPB1; LOW QUALITY PROTEIN: heat shock protein beta-1\tK04455 HSPB1; heat shock protein beta-1" }, { "name":"103592201 PPIL2; LOW QUALITY PROTEIN: peptidyl-prolyl cis-trans isomerase-like 2\tK10598 PPIL2; peptidyl-prolyl cis-trans isomerase-like 2 [EC:5.2.1.8]" }, { "name":"103586197 zinc finger protein 830-like\tK13104 ZNF830; zinc finger protein 830" }, { "name":"103590397 ZNF830; zinc finger protein 830\tK13104 ZNF830; zinc finger protein 830" }, { "name":"103582555 LOW QUALITY PROTEIN: retinitis pigmentosa 9 protein-like\tK19604 RP9; retinitis pigmentosa 9 protein" } ] } ] }, { "name":"Other components", "children":[ { "name":"Prp19 complex", "children":[ { "name":"103601223 PRPF19; pre-mRNA-processing factor 19\tK10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]" }, { "name":"103590421 CDC5L; cell division cycle 5-like protein\tK12860 CDC5L; pre-mRNA-splicing factor CDC5\/CEF1" }, { "name":"103589333 BCAS2; pre-mRNA-splicing factor SPF27\tK12861 BCAS2; pre-mRNA-splicing factor SPF27" }, { "name":"103592059 PLRG1; pleiotropic regulator 1 isoform X1\tK12862 PLRG1; pleiotropic regulator 1" }, { "name":"103592757 CWC15; spliceosome-associated protein CWC15 homolog\tK12863 CWC15; protein CWC15" }, { "name":"103592710 CTNNBL1; beta-catenin-like protein 1\tK12864 CTNNBL1; beta-catenin-like protein 1" }, { "name":"103582623 LOW QUALITY PROTEIN: heat shock 70 kDa protein 6-like\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8" }, { "name":"103587696 HSPA8; heat shock cognate 71 kDa protein\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8" }, { "name":"103592355 HSPA1A; heat shock 70 kDa protein 1A\/1B isoform X1\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8" }, { "name":"103592356 HSPA1L; heat shock 70 kDa protein 1-like\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8" }, { "name":"103589444 PQBP1; polyglutamine-binding protein 1 isoform X1\tK12865 PQBP1; polyglutamine-binding protein 1" }, { "name":"103598379 WBP11; WW domain-binding protein 11 isoform X1\tK12866 WBP11; WW domain-binding protein 11" } ] }, { "name":"Prp19-related factors", "children":[ { "name":"103589475 SNW domain-containing protein 1-like\tK06063 SNW1; SNW domain-containing protein 1" }, { "name":"103589478 LOW QUALITY PROTEIN: SNW domain-containing protein 1-like\tK06063 SNW1; SNW domain-containing protein 1" }, { "name":"103605611 SNW1; SNW domain-containing protein 1\tK06063 SNW1; SNW domain-containing protein 1" }, { "name":"103596857 XAB2; pre-mRNA-splicing factor SYF1 isoform X1\tK12867 SYF1; pre-mRNA-splicing factor SYF1" }, { "name":"103608482 SYF2; pre-mRNA-splicing factor SYF2\tK12868 SYF2; pre-mRNA-splicing factor SYF2" }, { "name":"103599464 crooked neck-like protein 1\tK12869 CRN; crooked neck" }, { "name":"103603684 CRNKL1; LOW QUALITY PROTEIN: crooked neck-like protein 1\tK12869 CRN; crooked neck" }, { "name":"103589393 AQR; intron-binding protein aquarius\tK12874 AQR; intron-binding protein aquarius" }, { "name":"103602066 BUD31; protein BUD31 homolog\tK12873 BUD31; bud site selection protein 31" }, { "name":"103591232 CCDC12; coiled-coil domain-containing protein 12 isoform X1\tK12871 CCDC12; coiled-coil domain-containing protein 12" }, { "name":"103584093 pre-mRNA-splicing factor ISY1 homolog\tK12870 ISY1; pre-mRNA-splicing factor ISY1" }, { "name":"103610017 PPIE; peptidyl-prolyl cis-trans isomerase E isoform X1\tK09564 PPIE; peptidyl-prolyl isomerase E (cyclophilin E) [EC:5.2.1.8]" }, { "name":"103604585 peptidyl-prolyl cis-trans isomerase-like 1\tK12733 PPIL1; peptidyl-prolyl cis-trans isomerase-like 1 [EC:5.2.1.8]" }, { "name":"103588587 PRCC; proline-rich protein PRCC isoform X1\tK13105 PRCC; proline-rich protein PRCC" }, { "name":"103602777 RBM22; pre-mRNA-splicing factor RBM22\tK12872 RBM22; pre-mRNA-splicing factor RBM22\/SLT11" }, { "name":"103588931 UPF0469 protein KIAA0907 homolog isoform X1\tK25780 KHDC4; kelch domain-containing protein 4" } ] }, { "name":"RES complex", "children":[ { "name":"103607444 BUD13; BUD13 homolog isoform X1\tK13106 BUD13; pre-mRNA-splicing factor CWC26" }, { "name":"103593737 RBMX2; RNA-binding motif protein, X-linked 2\tK13107 RBMX2; RNA-binding motif protein, X-linked 2" }, { "name":"103601485 LOW QUALITY PROTEIN: RNA-binding motif protein, X-linked 2-like\tK13107 RBMX2; RNA-binding motif protein, X-linked 2" }, { "name":"103589467 smad nuclear-interacting protein 1-like\tK13108 SNIP1; smad nuclear-interacting protein 1" }, { "name":"103596748 SNIP1; smad nuclear-interacting protein 1\tK13108 SNIP1; smad nuclear-interacting protein 1" } ] }, { "name":"Complex B specific factors", "children":[ { "name":"103601412 IK; protein Red\tK13109 IK; IK cytokine" }, { "name":"103605597 MFAP1; microfibrillar-associated protein 1\tK13110 MFAP1; pre-mRNA-splicing factor MFAP1\/SPP381" }, { "name":"103593739 LOW QUALITY PROTEIN: WD40 repeat-containing protein SMU1-like\tK13111 SMU1; WD40 repeat-containing protein SMU1" }, { "name":"103606419 SMU1; LOW QUALITY PROTEIN: WD40 repeat-containing protein SMU1\tK13111 SMU1; WD40 repeat-containing protein SMU1" }, { "name":"103601181 THRAP3; thyroid hormone receptor-associated protein 3\tK13112 THRAP3; thyroid hormone receptor-associated protein 3" }, { "name":"103609114 UBL5; ubiquitin-like protein 5\tK13113 UBL5; ubiquitin-like protein 5" } ] } ] } ] }, { "name":"Complex C", "children":[ { "name":"U2 snRNP components", "children":[ { "name":"Sm proteins", "children":[ { "name":"103610529 SNRPB; small nuclear ribonucleoprotein-associated proteins B and B' isoform X1\tK11086 SNRPB; small nuclear ribonucleoprotein B and B'" }, { "name":"103595028 LOW QUALITY PROTEIN: small nuclear ribonucleoprotein Sm D1-like\tK11087 SNRPD1; small nuclear ribonucleoprotein D1" }, { "name":"103603927 SNRPD1; small nuclear ribonucleoprotein Sm D1\tK11087 SNRPD1; small nuclear ribonucleoprotein D1" }, { "name":"103595246 SNRPD2; small nuclear ribonucleoprotein Sm D2\tK11096 SNRPD2; small nuclear ribonucleoprotein D2" }, { "name":"103609772 SNRPD3; small nuclear ribonucleoprotein Sm D3\tK11088 SNRPD3; small nuclear ribonucleoprotein D3" }, { "name":"103607790 SNRPE; small nuclear ribonucleoprotein E\tK11097 SNRPE; small nuclear ribonucleoprotein E" }, { "name":"103593289 small nuclear ribonucleoprotein F-like\tK11098 SNRPF; small nuclear ribonucleoprotein F" }, { "name":"103593751 SNRPF; small nuclear ribonucleoprotein F\tK11098 SNRPF; small nuclear ribonucleoprotein F" }, { "name":"103593229 SNRPG; small nuclear ribonucleoprotein G\tK11099 SNRPG; small nuclear ribonucleoprotein G" } ] }, { "name":"LSm proteins", "children":[ { "name":"103592386 LSM2; U6 snRNA-associated Sm-like protein LSm2\tK12621 LSM2; U6 snRNA-associated Sm-like protein LSm2" }, { "name":"103604629 LSM3; U6 snRNA-associated Sm-like protein LSm3\tK12622 LSM3; U6 snRNA-associated Sm-like protein LSm3" } ] }, { "name":"U2 SnRNP specific factors", "children":[ { "name":"103589157 SNRPA1; U2 small nuclear ribonucleoprotein A'\tK11092 SNRPA1; U2 small nuclear ribonucleoprotein A'" }, { "name":"103591996 SNRPB2; U2 small nuclear ribonucleoprotein B''\tK11094 SNRPB2; U2 small nuclear ribonucleoprotein B''" }, { "name":"103589400 SF3A1; splicing factor 3A subunit 1\tK12825 SF3A1; splicing factor 3A subunit 1" }, { "name":"103601163 SF3A2; splicing factor 3A subunit 2\tK12826 SF3A2; splicing factor 3A subunit 2" }, { "name":"103587874 SF3A3; splicing factor 3A subunit 3\tK12827 SF3A3; splicing factor 3A subunit 3" }, { "name":"103587113 SF3B1; splicing factor 3B subunit 1 isoform X1\tK12828 SF3B1; splicing factor 3B subunit 1" }, { "name":"103608191 SF3B2; splicing factor 3B subunit 2\tK12829 SF3B2; splicing factor 3B subunit 2" }, { "name":"103598315 SF3B3; splicing factor 3B subunit 3\tK12830 SF3B3; splicing factor 3B subunit 3" }, { "name":"103601195 SF3B4; splicing factor 3B subunit 4\tK12831 SF3B4; splicing factor 3B subunit 4" }, { "name":"103600556 SF3B5; splicing factor 3B subunit 5\tK12832 SF3B5; splicing factor 3B subunit 5" }, { "name":"103604536 SF3B6; splicing factor 3B subunit 6\tK12833 SF3B14; pre-mRNA branch site protein p14" }, { "name":"103595640 DDX42; ATP-dependent RNA helicase DDX42 isoform X1\tK12835 DDX42; ATP-dependent RNA helicase DDX42 [EC:5.6.2.7]" }, { "name":"103591644 PHF5A; PHD finger-like domain-containing protein 5A\tK12834 PHF5A; PHD finger-like domain-containing protein 5A" } ] } ] }, { "name":"U4\/U6.U5 tri-snRNP components", "children":[ { "name":"Sm proteins", "children":[ { "name":"103610529 SNRPB; small nuclear ribonucleoprotein-associated proteins B and B' isoform X1\tK11086 SNRPB; small nuclear ribonucleoprotein B and B'" }, { "name":"103595028 LOW QUALITY PROTEIN: small nuclear ribonucleoprotein Sm D1-like\tK11087 SNRPD1; small nuclear ribonucleoprotein D1" }, { "name":"103603927 SNRPD1; small nuclear ribonucleoprotein Sm D1\tK11087 SNRPD1; small nuclear ribonucleoprotein D1" }, { "name":"103595246 SNRPD2; small nuclear ribonucleoprotein Sm D2\tK11096 SNRPD2; small nuclear ribonucleoprotein D2" }, { "name":"103609772 SNRPD3; small nuclear ribonucleoprotein Sm D3\tK11088 SNRPD3; small nuclear ribonucleoprotein D3" }, { "name":"103607790 SNRPE; small nuclear ribonucleoprotein E\tK11097 SNRPE; small nuclear ribonucleoprotein E" }, { "name":"103593289 small nuclear ribonucleoprotein F-like\tK11098 SNRPF; small nuclear ribonucleoprotein F" }, { "name":"103593751 SNRPF; small nuclear ribonucleoprotein F\tK11098 SNRPF; small nuclear ribonucleoprotein F" }, { "name":"103593229 SNRPG; small nuclear ribonucleoprotein G\tK11099 SNRPG; small nuclear ribonucleoprotein G" } ] }, { "name":"U5 SnRNP specific factors", "children":[ { "name":"103595006 EFTUD2; 116 kDa U5 small nuclear ribonucleoprotein component\tK12852 EFTUD2; 116 kDa U5 small nuclear ribonucleoprotein component" }, { "name":"103586607 SNRNP200; U5 small nuclear ribonucleoprotein 200 kDa helicase\tK12854 SNRNP200; pre-mRNA-splicing helicase BRR2 [EC:5.6.2.6]" }, { "name":"103593792 PRPF6; pre-mRNA-processing factor 6 isoform X1\tK12855 PRPF6; pre-mRNA-processing factor 6" }, { "name":"103584891 PRPF8; pre-mRNA-processing-splicing factor 8\tK12856 PRPF8; pre-mRNA-processing factor 8" }, { "name":"103597089 SNRNP40; U5 small nuclear ribonucleoprotein 40 kDa protein\tK12857 SNRNP40; Prp8 binding protein" }, { "name":"103588861 DDX23; probable ATP-dependent RNA helicase DDX23\tK12858 DDX23; ATP-dependent RNA helicase DDX23\/PRP28 [EC:5.6.2.7]" } ] }, { "name":"U4\/U6.U5 tri-SnRNP related factors", "children":[ { "name":"103589119 CWC22; pre-mRNA-splicing factor CWC22 homolog\tK13100 CWC22; pre-mRNA-splicing factor CWC22" }, { "name":"103590787 SKIV2L2; superkiller viralicidic activity 2-like 2\tK12598 MTR4; ATP-dependent RNA helicase DOB1 [EC:5.6.2.6]" }, { "name":"103598229 DHX15; putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15\tK12820 DHX15; pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15\/PRP43 [EC:5.6.2.6]" }, { "name":"103610401 HSPB1; LOW QUALITY PROTEIN: heat shock protein beta-1\tK04455 HSPB1; heat shock protein beta-1" }, { "name":"103592201 PPIL2; LOW QUALITY PROTEIN: peptidyl-prolyl cis-trans isomerase-like 2\tK10598 PPIL2; peptidyl-prolyl cis-trans isomerase-like 2 [EC:5.2.1.8]" }, { "name":"103586197 zinc finger protein 830-like\tK13104 ZNF830; zinc finger protein 830" }, { "name":"103590397 ZNF830; zinc finger protein 830\tK13104 ZNF830; zinc finger protein 830" }, { "name":"103594986 TFIP11; tuftelin-interacting protein 11\tK13103 TFIP11; tuftelin-interacting protein 11" }, { "name":"103606153 LOW QUALITY PROTEIN: tuftelin-interacting protein 11-like\tK13103 TFIP11; tuftelin-interacting protein 11" }, { "name":"103582555 LOW QUALITY PROTEIN: retinitis pigmentosa 9 protein-like\tK19604 RP9; retinitis pigmentosa 9 protein" } ] } ] }, { "name":"Other components", "children":[ { "name":"Prp19-CDC5 complex", "children":[ { "name":"103601223 PRPF19; pre-mRNA-processing factor 19\tK10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]" }, { "name":"103590421 CDC5L; cell division cycle 5-like protein\tK12860 CDC5L; pre-mRNA-splicing factor CDC5\/CEF1" }, { "name":"103589333 BCAS2; pre-mRNA-splicing factor SPF27\tK12861 BCAS2; pre-mRNA-splicing factor SPF27" }, { "name":"103592710 CTNNBL1; beta-catenin-like protein 1\tK12864 CTNNBL1; beta-catenin-like protein 1" }, { "name":"103592757 CWC15; spliceosome-associated protein CWC15 homolog\tK12863 CWC15; protein CWC15" }, { "name":"103592059 PLRG1; pleiotropic regulator 1 isoform X1\tK12862 PLRG1; pleiotropic regulator 1" }, { "name":"103582623 LOW QUALITY PROTEIN: heat shock 70 kDa protein 6-like\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8" }, { "name":"103587696 HSPA8; heat shock cognate 71 kDa protein\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8" }, { "name":"103592355 HSPA1A; heat shock 70 kDa protein 1A\/1B isoform X1\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8" }, { "name":"103592356 HSPA1L; heat shock 70 kDa protein 1-like\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8" } ] }, { "name":"Prp19-related factors", "children":[ { "name":"103589475 SNW domain-containing protein 1-like\tK06063 SNW1; SNW domain-containing protein 1" }, { "name":"103589478 LOW QUALITY PROTEIN: SNW domain-containing protein 1-like\tK06063 SNW1; SNW domain-containing protein 1" }, { "name":"103605611 SNW1; SNW domain-containing protein 1\tK06063 SNW1; SNW domain-containing protein 1" }, { "name":"103596857 XAB2; pre-mRNA-splicing factor SYF1 isoform X1\tK12867 SYF1; pre-mRNA-splicing factor SYF1" }, { "name":"103608482 SYF2; pre-mRNA-splicing factor SYF2\tK12868 SYF2; pre-mRNA-splicing factor SYF2" }, { "name":"103599464 crooked neck-like protein 1\tK12869 CRN; crooked neck" }, { "name":"103603684 CRNKL1; LOW QUALITY PROTEIN: crooked neck-like protein 1\tK12869 CRN; crooked neck" }, { "name":"103589393 AQR; intron-binding protein aquarius\tK12874 AQR; intron-binding protein aquarius" }, { "name":"103602066 BUD31; protein BUD31 homolog\tK12873 BUD31; bud site selection protein 31" }, { "name":"103591232 CCDC12; coiled-coil domain-containing protein 12 isoform X1\tK12871 CCDC12; coiled-coil domain-containing protein 12" }, { "name":"103584093 pre-mRNA-splicing factor ISY1 homolog\tK12870 ISY1; pre-mRNA-splicing factor ISY1" }, { "name":"103604585 peptidyl-prolyl cis-trans isomerase-like 1\tK12733 PPIL1; peptidyl-prolyl cis-trans isomerase-like 1 [EC:5.2.1.8]" }, { "name":"103610017 PPIE; peptidyl-prolyl cis-trans isomerase E isoform X1\tK09564 PPIE; peptidyl-prolyl isomerase E (cyclophilin E) [EC:5.2.1.8]" }, { "name":"103602777 RBM22; pre-mRNA-splicing factor RBM22\tK12872 RBM22; pre-mRNA-splicing factor RBM22\/SLT11" } ] }, { "name":"RES complex", "children":[ { "name":"103607444 BUD13; BUD13 homolog isoform X1\tK13106 BUD13; pre-mRNA-splicing factor CWC26" }, { "name":"103593737 RBMX2; RNA-binding motif protein, X-linked 2\tK13107 RBMX2; RNA-binding motif protein, X-linked 2" }, { "name":"103601485 LOW QUALITY PROTEIN: RNA-binding motif protein, X-linked 2-like\tK13107 RBMX2; RNA-binding motif protein, X-linked 2" }, { "name":"103589467 smad nuclear-interacting protein 1-like\tK13108 SNIP1; smad nuclear-interacting protein 1" }, { "name":"103596748 SNIP1; smad nuclear-interacting protein 1\tK13108 SNIP1; smad nuclear-interacting protein 1" } ] }, { "name":"EJC\/TREX", "children":[ { "name":"103585567 ACIN1; LOW QUALITY PROTEIN: apoptotic chromatin condensation inducer in the nucleus\tK12875 ACIN1; apoptotic chromatin condensation inducer in the nucleus" }, { "name":"103606062 DDX39B; spliceosome RNA helicase DDX39B\tK12812 DDX39B; ATP-dependent RNA helicase UAP56\/SUB2 [EC:5.6.2.7]" }, { "name":"103595228 EIF4A3; eukaryotic initiation factor 4A-III isoform X1\tK13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7]" }, { "name":"103582913 CCDC174; coiled-coil domain-containing protein 174\tK25178 CCDC174; coiled-coil domain-containing protein 174" }, { "name":"103602732 MAGOH; protein mago nashi homolog\tK12877 MAGOH; protein mago nashi" }, { "name":"103603396 protein mago nashi homolog 2 isoform X1\tK12877 MAGOH; protein mago nashi" }, { "name":"103583512 pinin-like\tK13114 PNN; pinin" }, { "name":"103606410 pinin isoform X1\tK13114 PNN; pinin" }, { "name":"103595865 RBM8A; RNA-binding protein 8A isoform X1\tK12876 RBM8A; RNA-binding protein 8A" }, { "name":"103592849 THOC1; THO complex subunit 1\tK12878 THOC1; THO complex subunit 1" }, { "name":"103602048 THOC2; THO complex subunit 2 isoform X1\tK12879 THOC2; THO complex subunit 2" }, { "name":"103593473 THOC3; THO complex subunit 3\tK12880 THOC3; THO complex subunit 3" }, { "name":"103593346 ALYREF; THO complex subunit 4\tK12881 THOC4; THO complex subunit 4" } ] }, { "name":"Step II factors", "children":[ { "name":"103589522 CDC40; pre-mRNA-processing factor 17\tK12816 CDC40; pre-mRNA-processing factor 17" }, { "name":"103582437 PRPF18; LOW QUALITY PROTEIN: pre-mRNA-splicing factor 18\tK12817 PRPF18; pre-mRNA-splicing factor 18" }, { "name":"103602649 SLU7; pre-mRNA-splicing factor SLU7 isoform X1\tK12819 SLU7; pre-mRNA-processing factor SLU7" }, { "name":"103604404 DHX8; ATP-dependent RNA helicase DHX8\tK12818 DHX8; ATP-dependent RNA helicase DHX8\/PRP22 [EC:5.6.2.6]" }, { "name":"103603462 DHX38; pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 isoform X1\tK12815 DHX38; pre-mRNA-splicing factor ATP-dependent RNA helicase DHX38\/PRP16 [EC:5.6.2.6]" }, { "name":"103587938 RSRC1; serine\/Arginine-related protein 53\tK24594 RSRC1; arginine\/serine-rich coiled-coil protein 1" } ] }, { "name":"PPlases", "children":[ { "name":"103598156 PPIL3; peptidyl-prolyl cis-trans isomerase-like 3\tK12734 PPIL3; peptidyl-prolyl cis-trans isomerase-like 3 [EC:5.2.1.8]" }, { "name":"103593059 PPIL4; peptidyl-prolyl cis-trans isomerase-like 4\tK12735 PPIL4; peptidyl-prolyl cis-trans isomerase-like 4 [EC:5.2.1.8]" }, { "name":"103606366 PPIG; peptidyl-prolyl cis-trans isomerase G isoform X1\tK09566 PPIG; peptidyl-prolyl isomerase G (cyclophilin G) [EC:5.2.1.8]" }, { "name":"103586475 PPWD1; peptidylprolyl isomerase domain and WD repeat-containing protein 1 isoform X1\tK12736 PPWD1; peptidylprolyl isomerase domain and WD repeat-containing protein 1 [EC:5.2.1.8]" }, { "name":"103595019 CWC27; peptidyl-prolyl cis-trans isomerase CWC27 homolog isoform X1\tK12737 SDCCAG10; peptidyl-prolyl cis-trans isomerase SDCCAG10 [EC:5.2.1.8]" } ] }, { "name":"hnRNP proteins", "children":[ { "name":"103581330 HNRNPF; heterogeneous nuclear ribonucleoprotein F\tK12898 HNRNPF_H; heterogeneous nuclear ribonucleoprotein F\/H" }, { "name":"103585980 HNRNPH3; heterogeneous nuclear ribonucleoprotein H3 isoform X1\tK12898 HNRNPF_H; heterogeneous nuclear ribonucleoprotein F\/H" }, { "name":"103597475 HNRNPH1; heterogeneous nuclear ribonucleoprotein H isoform X1\tK12898 HNRNPF_H; heterogeneous nuclear ribonucleoprotein F\/H" }, { "name":"103600398 HNRNPH2; heterogeneous nuclear ribonucleoprotein H2\tK12898 HNRNPF_H; heterogeneous nuclear ribonucleoprotein F\/H" }, { "name":"103590571 HNRNPR; heterogeneous nuclear ribonucleoprotein R isoform X1\tK13161 HNRNPR; heterogeneous nuclear ribonucleoprotein R" }, { "name":"103586850 RALY; RNA-binding protein Raly\tK12895 RALY; RNA-binding protein Raly" } ] }, { "name":"Complex C specific factors", "children":[ { "name":"103585125 CCDC130; coiled-coil domain-containing protein 130 isoform X1\tK13115 CCDC130; coiled-coil domain-containing protein 130" }, { "name":"103589027 DDX41; probable ATP-dependent RNA helicase DDX41 isoform X1\tK13116 DDX41; ATP-dependent RNA helicase DDX41 [EC:5.6.2.7]" }, { "name":"103598013 DHX35; probable ATP-dependent RNA helicase DHX35 isoform X1\tK13117 DHX35; ATP-dependent RNA helicase DDX35 [EC:5.6.2.6]" }, { "name":"103606974 protein DGCR14 isoform X1\tK13118 DGCR14; protein DGCR14" }, { "name":"103603894 FAM50B; protein FAM50B\tK13119 FAM50; protein FAM50" }, { "name":"103604376 FAM50A; protein FAM50A isoform X1\tK13119 FAM50; protein FAM50" }, { "name":"103582255 FAM32A; protein FAM32A\tK13120 FAM32A; protein FAM32A" }, { "name":"103604264 FRA10AC1; protein FRA10AC1\tK13121 FRA10AC1; protein FRA10AC1" }, { "name":"103590193 FRG1; protein FRG1 isoform X1\tK13122 FRG1; protein FRG1" }, { "name":"103601144 GPATCH1; G patch domain-containing protein 1\tK13123 GPATCH1; G patch domain-containing protein 1" }, { "name":"103600663 WDR83; WD repeat domain-containing protein 83\tK13124 MORG1; mitogen-activated protein kinase organizer 1" }, { "name":"103592603 NOSIP; nitric oxide synthase-interacting protein isoform X1\tK13125 NOSIP; nitric oxide synthase-interacting protein" }, { "name":"103585000 PABPC4; polyadenylate-binding protein 4 isoform X1\tK13126 PABPC; polyadenylate-binding protein" }, { "name":"103586684 PABPC5; polyadenylate-binding protein 5\tK13126 PABPC; polyadenylate-binding protein" }, { "name":"103594475 PABPC1; polyadenylate-binding protein 1\tK13126 PABPC; polyadenylate-binding protein" }, { "name":"103597173 PABPC4L; polyadenylate-binding protein 4-like\tK13126 PABPC; polyadenylate-binding protein" }, { "name":"103604428 PABPC1L; polyadenylate-binding protein 1-like isoform X1\tK13126 PABPC; polyadenylate-binding protein" }, { "name":"103606920 polyadenylate-binding protein 1-like 2\tK13126 PABPC; polyadenylate-binding protein" }, { "name":"103601779 RING finger protein 113A-like\tK13127 RNF113A; RING finger protein 113A" }, { "name":"103604788 RING finger protein 113A-like\tK13127 RNF113A; RING finger protein 113A" }, { "name":"103605454 RNF113A; RING finger protein 113A\tK13127 RNF113A; RING finger protein 113A" }, { "name":"103594986 TFIP11; tuftelin-interacting protein 11\tK13103 TFIP11; tuftelin-interacting protein 11" }, { "name":"103606153 LOW QUALITY PROTEIN: tuftelin-interacting protein 11-like\tK13103 TFIP11; tuftelin-interacting protein 11" }, { "name":"103594490 ZCCHC8; zinc finger CCHC domain-containing protein 8 isoform X1\tK13128 ZCCHC8; zinc finger CCHC domain-containing protein 8" }, { "name":"103598842 CACTIN; cactin\tK25058 CACTIN; cactin" }, { "name":"103600119 SDE2; protein SDE2 homolog\tK25059 SDE2; replication stress response regulator SDE2" }, { "name":"103610283 PRKRIP1; PRKR-interacting protein 1\tK26159 PRKRIP1; PRKR-interacting protein 1" }, { "name":"103609442 uncharacterized protein C9orf78-like\tK28609 C9ORF78; splicing factor C9orf78" }, { "name":"103606871 LENG1; leukocyte receptor cluster member 1 isoform X1\tK28610 LENG1; leukocyte receptor cluster member 1" } ] } ] } ] }, { "name":"Other splicing related proteins", "children":[ { "name":"Proteins involved in snRNP biogenesis", "children":[ { "name":"SMN complex factors", "children":[ { "name":"103592790 survival motor neuron protein isoform X1\tK13129 SMN; survival motor neuron protein" }, { "name":"103606412 GEMIN2; LOW QUALITY PROTEIN: gem-associated protein 2\tK13130 GEMIN2; gem associated protein 2" }, { "name":"103589923 DDX20; probable ATP-dependent RNA helicase DDX20\tK13131 DDX20; ATP-dependent RNA helicase DDX20 [EC:5.6.2.7]" }, { "name":"103608673 GEMIN4; gem-associated protein 4\tK13132 GEMIN4; gem associated protein 4" }, { "name":"103590845 GEMIN5; gem-associated protein 5\tK13133 GEMIN5; gem associated protein 5" }, { "name":"103610270 GEMIN6; gem-associated protein 6\tK13134 GEMIN6; gem associated protein 6" }, { "name":"103602186 GEMIN7; gem-associated protein 7\tK13135 GEMIN7; gem associated protein 7" }, { "name":"103605141 GEMIN8; gem-associated protein 8 isoform X1\tK13136 GEMIN8; gem associated protein 8" }, { "name":"103605198 STRAP; serine-threonine kinase receptor-associated protein\tK13137 STRAP; serine-threonine kinase receptor-associated protein" } ] }, { "name":"Integrator complex", "children":[ { "name":"103591732 INTS1; integrator complex subunit 1\tK13138 INTS1; integrator complex subunit 1" }, { "name":"103593175 INTS2; integrator complex subunit 2\tK13139 INTS2; integrator complex subunit 2" }, { "name":"103586355 INTS3; integrator complex subunit 3 isoform X1\tK13140 INTS3; integrator complex subunit 3 (SOSS complex subunit A)" }, { "name":"103585113 INTS4; integrator complex subunit 4\tK13141 INTS4; integrator complex subunit 4" }, { "name":"103591108 INTS5; integrator complex subunit 5\tK13142 INTS5; integrator complex subunit 5" }, { "name":"103584977 INTS6; integrator complex subunit 6 isoform X1\tK13143 INTS6; integrator complex subunit 6" }, { "name":"103598300 INTS7; integrator complex subunit 7\tK13144 INTS7; integrator complex subunit 7" }, { "name":"103599681 INTS9; integrator complex subunit 9\tK13146 INTS9; integrator complex subunit 9" }, { "name":"103601180 INTS10; integrator complex subunit 10\tK13147 INTS10; integrator complex subunit 10" }, { "name":"103594866 CPSF3L; integrator complex subunit 11 isoform X1\tK13148 CPSF3L; integrator complex subunit 11 [EC:3.1.27.-]" }, { "name":"103599737 INTS12; integrator complex subunit 12 isoform X1\tK13149 INTS12; integrator complex subunit 12" }, { "name":"103605664 ASUN; protein asunder homolog\tK28447 INTS13; integrator complex subunit 13" }, { "name":"103592586 VWA9; von Willebrand factor A domain-containing protein 9\tK28448 INTS14; integrator complex subunit 14" }, { "name":"103601694 uncharacterized protein C7orf26 homolog\tK28449 INTS15; integrator complex subunit 15" } ] }, { "name":"Other proteins involved in snRNP biogenesis", "children":[ { "name":"103610695 COIL; coilin\tK13150 COIL; coilin" }, { "name":"103588289 SMNDC1; survival of motor neuron-related-splicing factor 30 isoform X1\tK12839 SMNDC1; survival of motor neuron-related-splicing factor 30" }, { "name":"103596426 SNUPN; snurportin-1\tK13151 SNUPN; snurportin-1" }, { "name":"103592430 USB1; U6 snRNA phosphodiesterase\tK23093 USB1; U6 snRNA phosphodiesterase [EC:3.1.4.-]" }, { "name":"103607733 THUMP domain-containing protein 2-like\tK28400 THUMPD2; U6 snRNA (guanine-N(2))-methyltransferase THUMPD2 [EC:2.1.1.-]" }, { "name":"103586200 TRMT112; tRNA methyltransferase 112 homolog\tK15448 TRM112; multifunctional methyltransferase subunit TRM112" }, { "name":"103585055 CLNS1A; methylosome subunit pICln\tK05019 CLNS1A; chloride channel, nucleotide-sensitive, 1A" }, { "name":"103597003 TGS1; trimethylguanosine synthase isoform X1\tK14292 TGS1; trimethylguanosine synthase [EC:2.1.1.-]" }, { "name":"103595743 DDX26B; protein DDX26B isoform X1\tK13180 INTS6L; integrator complex subunit 6-like" }, { "name":"103607445 ZPR1; zinc finger protein ZPR1\tK06874 ZPR1; zinc finger protein ZPR1" } ] } ] }, { "name":"Minor spliceosome components", "children":[ { "name":"Minor spliceosome specific factors", "children":[ { "name":"103592712 ZMAT5; zinc finger matrin-type protein 5\tK13152 ZMAT5; U11\/U12 small nuclear ribonucleoprotein 20 kDa protein" }, { "name":"103602854 SNRNP25; U11\/U12 small nuclear ribonucleoprotein 25 kDa protein\tK13153 SNRNP25; U11\/U12 small nuclear ribonucleoprotein 25 kDa protein" }, { "name":"103588736 ZCRB1; zinc finger CCHC-type and RNA-binding motif-containing protein 1\tK13154 ZCRB1; U11\/U12 small nuclear ribonucleoprotein 31 kDa protein" }, { "name":"103606838 SNRNP35; U11\/U12 small nuclear ribonucleoprotein 35 kDa protein\tK13155 SNRNP35; U11\/U12 small nuclear ribonucleoprotein 35 kDa protein" }, { "name":"103596457 SNRNP48; U11\/U12 small nuclear ribonucleoprotein 48 kDa protein\tK13156 SNRNP48; U11\/U12 small nuclear ribonucleoprotein 48 kDa protein" }, { "name":"103593881 RNPC3; RNA-binding protein 40 isoform X1\tK13157 RNPC3; U11\/U12 small nuclear ribonucleoprotein 65 kDa protein" } ] }, { "name":"Minor spliceosome associated proteins", "children":[ { "name":"103590108 RBM48; RNA-binding protein 48 isoform X1\tK24824 RBM48; RNA-binding protein 48" }, { "name":"103585164 ARMC7; armadillo repeat-containing protein 7\tK24825 ARMC7; armadillo repeat-containing protein 7" }, { "name":"103592567 CRIPT; cysteine-rich PDZ-binding protein\tK24826 CRIPT; cysteine-rich PDZ-binding protein" }, { "name":"103600059 SCNM1; sodium channel modifier 1\tK24827 SCNM1; sodium channel modifier 1" }, { "name":"103592201 PPIL2; LOW QUALITY PROTEIN: peptidyl-prolyl cis-trans isomerase-like 2\tK10598 PPIL2; peptidyl-prolyl cis-trans isomerase-like 2 [EC:5.2.1.8]" }, { "name":"103594654 CCDC84; coiled-coil domain-containing protein 84\tK26160 CENATAC; centrosomal AT-AC splicing factor" } ] } ] }, { "name":"Spliceosome associated proteins (SAPs)", "children":[ { "name":"hnRNP proteins", "children":[ { "name":"103592624 HNRNPA0; heterogeneous nuclear ribonucleoprotein A0\tK12894 HNRNPA0; heterogeneous nuclear ribonucleoprotein A0" }, { "name":"103603907 HNRNPA2B1; heterogeneous nuclear ribonucleoproteins A2\/B1 isoform X1\tK13158 HNRNPA2B1; heterogeneous nuclear ribonucleoprotein A2\/B1" }, { "name":"103589039 HNRNPAB; heterogeneous nuclear ribonucleoprotein A\/B isoform X1\tK13044 HNRNPABD; heterogeneous nuclear ribonucleoprotein A\/B\/D" }, { "name":"103607340 HNRNPD; heterogeneous nuclear ribonucleoprotein D0 isoform X1\tK13044 HNRNPABD; heterogeneous nuclear ribonucleoprotein A\/B\/D" }, { "name":"103607342 HNRNPDL; heterogeneous nuclear ribonucleoprotein D-like\tK13044 HNRNPABD; heterogeneous nuclear ribonucleoprotein A\/B\/D" }, { "name":"103591467 HNRNPL; heterogeneous nuclear ribonucleoprotein L isoform X1\tK13159 HNRNPL; heterogeneous nuclear ribonucleoprotein L" }, { "name":"103592535 HNRNPLL; heterogeneous nuclear ribonucleoprotein L-like\tK13159 HNRNPL; heterogeneous nuclear ribonucleoprotein L" }, { "name":"103596231 SYNCRIP; heterogeneous nuclear ribonucleoprotein Q isoform X1\tK13160 SYNCRIP; heterogeneous nuclear ribonucleoprotein Q" }, { "name":"103599187 HNRNPUL1; heterogeneous nuclear ribonucleoprotein U-like protein 1 isoform X1\tK15047 HNRNPUL1; heterogeneous nuclear ribonucleoprotein U-like protein 1" }, { "name":"103591109 HNRNPUL2; heterogeneous nuclear ribonucleoprotein U-like protein 2\tK28611 HNRNPUL2; heterogeneous nuclear ribonucleoprotein U-like protein 2" }, { "name":"103592875 PCBP2; poly(rC)-binding protein 2 isoform X1\tK13162 PCBP2; poly(rC)-binding protein 2" }, { "name":"103598102 MSL1; male-specific lethal 1 homolog\tK13163 MSL1; male-specific lethal 1" }, { "name":"103599914 MSL2; E3 ubiquitin-protein ligase MSL2\tK13164 MSL2; male-specific lethal 2" } ] }, { "name":"SR proteins", "children":[ { "name":"103605648 SRSF11; serine\/arginine-rich splicing factor 11 isoform X1\tK12899 SRSF11; serine\/arginine-rich splicing factor 11" }, { "name":"103610968 SREK1; splicing regulatory glutamine\/lysine-rich protein 1 isoform X1\tK13165 SREK1; splicing regulatory glutamine\/lysine-rich protein 1" }, { "name":"103588133 SUGP2; SURP and G-patch domain-containing protein 2\tK13166 SUGP2; SURP and G-patch domain-containing protein 2" }, { "name":"103585521 SCAF4; splicing factor, arginine\/serine-rich 15 isoform X1\tK13167 SCAF4; SR-related and CTD-associated factor 4" }, { "name":"103602184 CLASRP; CLK4-associating serine\/arginine rich protein\tK13168 CLASRP; CLK4-associating serine\/arginine rich protein" }, { "name":"103586752 AKAP17A; A-kinase anchor protein 17A\tK13169 AKAP17; A-kinase anchor protein 17" }, { "name":"103589289 A-kinase anchor protein 17B-like\tK13169 AKAP17; A-kinase anchor protein 17" }, { "name":"103591944 PNISR; arginine\/serine-rich protein PNISR isoform X1\tK13170 PNISR; arginine\/serine-rich protein PNISR" }, { "name":"103597406 SRSF12; serine\/arginine-rich splicing factor 12\tK25101 SRSF12; serine\/arginine-rich splicing factor 12" }, { "name":"103603292 ARL6IP4; ADP-ribosylation factor-like protein 6-interacting protein 4\tK28949 ARL6IP4; ADP-ribosylation factor-like protein 6-interacting protein 4" } ] }, { "name":"SR-related proteins", "children":[ { "name":"103592317 SRRM1; serine\/arginine repetitive matrix protein 1 isoform X1\tK13171 SRRM1; serine\/arginine repetitive matrix protein 1" }, { "name":"103585349 SRRM2; serine\/arginine repetitive matrix protein 2 isoform X1\tK13172 SRRM2; serine\/arginine repetitive matrix protein 2" }, { "name":"103589678 ARGLU1; arginine and glutamate-rich protein 1 isoform X1\tK13173 ARGLU1; arginine and glutamate-rich protein 1" }, { "name":"103585992 SON; protein SON isoform X1\tK23718 SON; protein SON" }, { "name":"103601201 PSIP1; PC4 and SFRS1-interacting protein isoform X1\tK25057 PSIP1; PC4 and SFRS1-interacting protein" }, { "name":"103583531 ILDR1; immunoglobulin-like domain-containing receptor 1\tK25781 ILDR1; immunoglobulin-like domain-containing receptor 1" }, { "name":"103605501 ILDR2; immunoglobulin-like domain-containing receptor 2\tK25782 ILDR2; immunoglobulin-like domain-containing receptor 2" }, { "name":"103589784 ZRANB2; zinc finger Ran-binding domain-containing protein 2 isoform X1\tK26076 ZRANB2; zinc finger Ran-binding domain-containing protein 2" } ] }, { "name":"TREX complex", "children":[ { "name":"103592849 THOC1; THO complex subunit 1\tK12878 THOC1; THO complex subunit 1" }, { "name":"103602048 THOC2; THO complex subunit 2 isoform X1\tK12879 THOC2; THO complex subunit 2" }, { "name":"103593473 THOC3; THO complex subunit 3\tK12880 THOC3; THO complex subunit 3" }, { "name":"103593346 ALYREF; THO complex subunit 4\tK12881 THOC4; THO complex subunit 4" }, { "name":"103592719 THOC5; THO complex subunit 5 homolog\tK13174 THOC5; THO complex subunit 5" }, { "name":"103585360 THOC6; THO complex subunit 6 homolog\tK13175 THOC6; THO complex subunit 6" }, { "name":"103582382 THOC7; THO complex subunit 7 homolog\tK13176 THOC7; THO complex subunit 7" }, { "name":"103606062 DDX39B; spliceosome RNA helicase DDX39B\tK12812 DDX39B; ATP-dependent RNA helicase UAP56\/SUB2 [EC:5.6.2.7]" } ] }, { "name":"RNA helicase-like proteins", "children":[ { "name":"103597685 DDX1; ATP-dependent RNA helicase DDX1\tK13177 DDX1; ATP-dependent RNA helicase DDX1 [EC:5.6.2.7]" }, { "name":"103593945 ATP-dependent RNA helicase DDX3X-like\tK11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]" }, { "name":"103600792 DDX3X; ATP-dependent RNA helicase DDX3X isoform X1\tK11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]" }, { "name":"103585806 DDX17; probable ATP-dependent RNA helicase DDX17 isoform X1\tK13178 DDX17; ATP-dependent RNA helicase DDX17 [EC:5.6.2.7]" }, { "name":"103587994 LOW QUALITY PROTEIN: ATP-dependent RNA helicase DDX18-like\tK13179 DDX18; ATP-dependent RNA helicase DDX18\/HAS1 [EC:5.6.2.7]" }, { "name":"103602425 DDX18; ATP-dependent RNA helicase DDX18\tK13179 DDX18; ATP-dependent RNA helicase DDX18\/HAS1 [EC:5.6.2.7]" }, { "name":"103597959 DDX27; probable ATP-dependent RNA helicase DDX27 isoform X1\tK13181 DDX27; ATP-dependent RNA helicase DDX27 [EC:5.6.2.7]" }, { "name":"103585140 DDX39A; ATP-dependent RNA helicase DDX39A\tK13182 DDX39; ATP-dependent RNA helicase DDX39 [EC:5.6.2.7]" }, { "name":"103595482 DDX43; probable ATP-dependent RNA helicase DDX43 isoform X1\tK17043 DDX43; ATP-dependent RNA helicase DDX43 [EC:5.6.2.7]" }, { "name":"103595142 DDX50; ATP-dependent RNA helicase DDX50 isoform X1\tK13183 DDX50; ATP-dependent RNA helicase DDX50 [EC:5.6.2.7]" }, { "name":"103610982 DHX9; ATP-dependent RNA helicase A\tK13184 DHX9; ATP-dependent RNA\/DNA helicase DHX9 [EC:5.6.2.6 5.6.2.4]" }, { "name":"103596872 DHX30; putative ATP-dependent RNA helicase DHX30 isoform X1\tK13185 DHX30; ATP-dependent RNA helicase DHX30 [EC:5.6.2.6]" }, { "name":"103597167 DHX32; putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX32\tK18994 DHX32; pre-mRNA-splicing factor ATP-dependent RNA helicase DHX32 [EC:5.6.2.6]" }, { "name":"103606309 YTHDC2; probable ATP-dependent RNA helicase YTHDC2\tK20099 YTHDC2; ATP-dependent RNA helicase YTHDC2 [EC:5.6.2.6]" }, { "name":"103593849 DQX1; ATP-dependent RNA helicase DQX1\tK14433 DQX1; ATP-dependent helicase [EC:5.6.2.-]" } ] }, { "name":"RNA binding proteins (RBPs)", "children":[ { "name":"103589455 RBM3; putative RNA-binding protein 3 isoform X1\tK13186 RBM3; RNA-binding protein 3" }, { "name":"103595564 RBM4B; RNA-binding protein 4B\tK13187 RBM4; RNA-binding protein 4" }, { "name":"103594591 RBM7; RNA-binding protein 7 isoform X1\tK13188 RBM7; RNA-binding protein 7" }, { "name":"103597515 RBM11; splicing regulator RBM11\tK25005 RBM11; splicing regulator RBM11" }, { "name":"103588075 RNA-binding protein 12 isoform X1\tK24526 RBM12; RNA-binding protein 12" }, { "name":"103589415 LOW QUALITY PROTEIN: RNA-binding protein 12-like\tK24526 RBM12; RNA-binding protein 12" }, { "name":"103593439 RBM12B; RNA-binding protein 12B\tK24526 RBM12; RNA-binding protein 12" }, { "name":"103582983 RNA-binding protein 14 isoform X1\tK13189 RBM14; RNA-binding protein 14" }, { "name":"103595576 RBM14; RNA-binding protein 14\tK13189 RBM14; RNA-binding protein 14" }, { "name":"103586788 RBM15B; putative RNA-binding protein 15B\tK13190 RBM15; RNA-binding protein 15" }, { "name":"103590909 RBM15; putative RNA-binding protein 15 isoform X1\tK13190 RBM15; RNA-binding protein 15" }, { "name":"103592485 SCAF8; protein SCAF8\tK13191 RBM16; RNA-binding protein 16" }, { "name":"103606262 protein SCAF8 isoform X1\tK13191 RBM16; RNA-binding protein 16" }, { "name":"103589938 RBM18; probable RNA-binding protein 18 isoform X1\tK24527 RBM18; RNA-binding protein 18" }, { "name":"103605311 RBM38; RNA-binding protein 38\tK25006 RBM24_38; RNA-binding protein 24\/38" }, { "name":"103606813 RBM24; RNA-binding protein 24\tK25006 RBM24_38; RNA-binding protein 24\/38" }, { "name":"103603345 RBM26; RNA-binding protein 26 isoform X1\tK13192 RBM26; RNA-binding protein 26" }, { "name":"103587575 RBM27; RNA-binding protein 27 isoform X1\tK13193 RBM27; RNA-binding protein 27" }, { "name":"103601392 RNA-binding motif protein, X chromosome-like\tK28612 RBMXL; RNA binding motif protein, X-linked-like" }, { "name":"103586676 RBPMS2; RNA-binding protein with multiple splicing 2\tK25091 RBPMS; RNA-binding protein with multiple splicing" }, { "name":"103591181 RBPMS; RNA-binding protein with multiple splicing\tK25091 RBPMS; RNA-binding protein with multiple splicing" }, { "name":"103608124 ADAR; double-stranded RNA-specific adenosine deaminase isoform X1\tK12968 ADAR; double-stranded RNA-specific adenosine deaminase [EC:3.5.4.37]" }, { "name":"103599418 ADARB2; LOW QUALITY PROTEIN: double-stranded RNA-specific editase B2\tK13194 ADARB; double stranded RNA-specific editase B [EC:3.5.-.-]" }, { "name":"103608103 ADARB1; double-stranded RNA-specific editase 1\tK13194 ADARB; double stranded RNA-specific editase B [EC:3.5.-.-]" }, { "name":"103586323 chromobox protein homolog 3-like\tK11586 CBX3; chromobox protein 3" }, { "name":"103603906 CBX3; chromobox protein homolog 3 isoform X1\tK11586 CBX3; chromobox protein 3" }, { "name":"103586715 CIRBP; cold-inducible RNA-binding protein\tK13195 CIRBP; cold-inducible RNA-binding protein" }, { "name":"103609031 YBX3; Y-box-binding protein 3\tK06099 CSDA; cold shock domain protein A" }, { "name":"103599232 DPF2; zinc finger protein ubi-d4 isoform X1\tK13196 DPF2; zinc finger protein ubi-d4" }, { "name":"103587447 IGF2BP1; insulin-like growth factor 2 mRNA-binding protein 1 isoform X1\tK17391 IGF2BP1; insulin-like growth factor 2 mRNA-binding protein 1" }, { "name":"103585537 IGF2BP3; insulin-like growth factor 2 mRNA-binding protein 3 isoform X1\tK13197 IGF2BP3; insulin-like growth factor 2 mRNA-binding protein 3" }, { "name":"103582396 KH domain-containing, RNA-binding, signal transduction-associated protein 1\tK13198 KHDRBS1; KH domain-containing, RNA-binding, signal transduction-associated protein 1" }, { "name":"103606526 KHDRBS1; KH domain-containing, RNA-binding, signal transduction-associated protein 1\tK13198 KHDRBS1; KH domain-containing, RNA-binding, signal transduction-associated protein 1" }, { "name":"103607220 KH domain-containing, RNA-binding, signal transduction-associated protein 2-like\tK17843 KHDRBS2; KH domain-containing, RNA-binding, signal transduction-associated protein 2" }, { "name":"103598758 KHDRBS3; KH domain-containing, RNA-binding, signal transduction-associated protein 3\tK14942 KHDRBS3; KH domain-containing, RNA-binding, signal transduction-associated protein 3" }, { "name":"103586194 MBNL2; muscleblind-like protein 2 isoform X1\tK14943 MBNL; muscleblind" }, { "name":"103590627 MBNL1; muscleblind-like protein 1 isoform X1\tK14943 MBNL; muscleblind" }, { "name":"103592083 MBNL3; muscleblind-like protein 3 isoform X1\tK14943 MBNL; muscleblind" }, { "name":"103595250 NOVA2; RNA-binding protein Nova-2\tK14944 NOVA; RNA-binding protein Nova" }, { "name":"103601273 NOVA1; RNA-binding protein Nova-1\tK14944 NOVA; RNA-binding protein Nova" }, { "name":"103591970 QKI; protein quaking isoform X1\tK14945 QKI; protein quaking" }, { "name":"103585428 RBFOX1; RNA binding protein fox-1 homolog 1 isoform X1\tK14946 RBFOX; RNA binding protein fox-1" }, { "name":"103593215 RBFOX3; RNA binding protein fox-1 homolog 3 isoform X1\tK14946 RBFOX; RNA binding protein fox-1" }, { "name":"103605386 RBFOX2; RNA binding protein fox-1 homolog 2 isoform X1\tK14946 RBFOX; RNA binding protein fox-1" }, { "name":"103592007 SERBP1; plasminogen activator inhibitor 1 RNA-binding protein\tK13199 SERBP1; plasminogen activator inhibitor 1 RNA-binding protein" }, { "name":"103607910 STRBP; spermatid perinuclear RNA-binding protein\tK13200 STRBP; spermatid perinuclear RNA-binding protein" }, { "name":"103593228 TIA1; nucleolysin TIA-1 isoform p40 isoform X1\tK13201 TIA1; nucleolysin TIA-1\/TIAR" }, { "name":"103601681 TIAL1; nucleolysin TIAR isoform X1\tK13201 TIA1; nucleolysin TIA-1\/TIAR" }, { "name":"103592240 TOE1; target of EGR1 protein 1\tK13202 TOE1; target of EGR1 protein 1" }, { "name":"103590514 ZFR; zinc finger RNA-binding protein isoform X1\tK13203 ZFR; zinc finger RNA-binding protein" }, { "name":"103593744 ZNF326; DBIRD complex subunit ZNF326 isoform X1\tK13204 ZNF326; zinc finger protein 326" }, { "name":"103598522 YTHDC1; YTH domain-containing protein 1 isoform X1\tK20100 YTHDC1; YTH domain-containing protein 1" }, { "name":"103582286 NF-kappa-B-activating protein\tK25931 NKAP; NF-kappa-B-activating protein" }, { "name":"103599306 NKAPL; NKAP-like protein\tK25931 NKAP; NF-kappa-B-activating protein" }, { "name":"103605458 NKAP; NF-kappa-B-activating protein\tK25931 NKAP; NF-kappa-B-activating protein" } ] }, { "name":"Other SAPs", "children":[ { "name":"103587363 AAR2; protein AAR2 homolog\tK13205 AAR2; A1 cistron-splicing factor AAR2" }, { "name":"103599963 NSRP1; nuclear speckle splicing regulatory protein 1 isoform X1\tK13206 CCDC55; coiled-coil domain-containing protein 55" }, { "name":"103598155 CLK1; dual specificity protein kinase CLK1\tK23561 CLK1_4; dual specificity protein kinase CLK1\/4 [EC:2.7.12.1]" }, { "name":"103606394 CLK4; dual specificity protein kinase CLK4 isoform X1\tK23561 CLK1_4; dual specificity protein kinase CLK1\/4 [EC:2.7.12.1]" }, { "name":"103588059 CLK3; LOW QUALITY PROTEIN: dual specificity protein kinase CLK3\tK08823 CLK2_3; dual specificity protein kinase CLK2\/3 [EC:2.7.12.1]" }, { "name":"103596186 CLK2; dual specificity protein kinase CLK2 isoform X1\tK08823 CLK2_3; dual specificity protein kinase CLK2\/3 [EC:2.7.12.1]" }, { "name":"103589161 CELF6; CUGBP Elav-like family member 6\tK13207 CUGBP; CUG-BP- and ETR3-like factor" }, { "name":"103592431 CELF3; CUGBP Elav-like family member 3 isoform X1\tK13207 CUGBP; CUG-BP- and ETR3-like factor" }, { "name":"103599452 CUGBP Elav-like family member 4 isoform X1\tK13207 CUGBP; CUG-BP- and ETR3-like factor" }, { "name":"103600920 CELF1; CUGBP Elav-like family member 1 isoform X1\tK13207 CUGBP; CUG-BP- and ETR3-like factor" }, { "name":"103601376 CUGBP Elav-like family member 5\tK13207 CUGBP; CUG-BP- and ETR3-like factor" }, { "name":"103605902 CELF2; CUGBP Elav-like family member 2 isoform X1\tK13207 CUGBP; CUG-BP- and ETR3-like factor" }, { "name":"103591502 DNAJC6; putative tyrosine-protein phosphatase auxilin isoform X1\tK09526 DNAJC6; DnaJ homolog subfamily C member 6" }, { "name":"103603033 DNAJC8; dnaJ homolog subfamily C member 8\tK09528 DNAJC8; DnaJ homolog subfamily C member 8" }, { "name":"103600359 DNAJC13; dnaJ homolog subfamily C member 13\tK09533 DNAJC13; DnaJ homolog subfamily C member 13" }, { "name":"103583684 ELAV-like protein 3\tK13208 ELAVL2_3_4; ELAV like protein 2\/3\/4" }, { "name":"103586188 ELAVL2; ELAV-like protein 2 isoform X1\tK13208 ELAVL2_3_4; ELAV like protein 2\/3\/4" }, { "name":"103592467 ELAVL4; ELAV-like protein 4 isoform X1\tK13208 ELAVL2_3_4; ELAV like protein 2\/3\/4" }, { "name":"103602097 ELAVL3; ELAV-like protein 3 isoform X1\tK13208 ELAVL2_3_4; ELAV like protein 2\/3\/4" }, { "name":"103586043 ESRP2; epithelial splicing regulatory protein 2\tK14947 ESRP1_2; epithelial splicing regulatory protein 1\/2" }, { "name":"103598476 ESRP1; epithelial splicing regulatory protein 1\tK14947 ESRP1_2; epithelial splicing regulatory protein 1\/2" }, { "name":"103588200 EWSR1; LOW QUALITY PROTEIN: RNA-binding protein EWS\tK13209 EWSR1; RNA-binding protein EWS" }, { "name":"103586990 FUBP1; far upstream element-binding protein 1 isoform X1\tK13210 FUBP; far upstream element-binding protein" }, { "name":"103592942 KHSRP; far upstream element-binding protein 2\tK13210 FUBP; far upstream element-binding protein" }, { "name":"103597825 FUBP3; far upstream element-binding protein 3\tK13210 FUBP; far upstream element-binding protein" }, { "name":"103599898 PAXBP1; PAX3- and PAX7-binding protein 1\tK13211 GCFC; GC-rich sequence DNA-binding factor" }, { "name":"103588978 LUC7L3; luc7-like protein 3 isoform X1\tK13212 LUC7L; RNA-binding protein Luc7-like" }, { "name":"103604803 LUC7L; putative RNA-binding protein Luc7-like 1 isoform X1\tK13212 LUC7L; RNA-binding protein Luc7-like" }, { "name":"103605849 putative RNA-binding protein Luc7-like 2 isoform X1\tK13212 LUC7L; RNA-binding protein Luc7-like" }, { "name":"103587177 MATR3; matrin-3 isoform X1\tK13213 MATR3; matrin 3" }, { "name":"103586312 NONO; non-POU domain-containing octamer-binding protein isoform X1\tK13214 NONO; non-POU domain-containing octamer-binding protein" }, { "name":"103587591 PSPC1; paraspeckle component 1\tK24993 PSPC1; paraspeckle component 1" }, { "name":"103601276 SFPQ; splicing factor, proline- and glutamine-rich\tK13219 SFPQ; splicing factor, proline- and glutamine-rich" }, { "name":"103594614 NRIP2; nuclear receptor-interacting protein 2\tK13215 NRIP2; nuclear receptor-interacting protein 2" }, { "name":"103582032 LOW QUALITY PROTEIN: serine\/threonine-protein phosphatase PP1-beta catalytic subunit-like\tK06269 PPP1C; serine\/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]" }, { "name":"103585436 PPP1CB; serine\/threonine-protein phosphatase PP1-beta catalytic subunit\tK06269 PPP1C; serine\/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]" }, { "name":"103589995 PPP1CA; LOW QUALITY PROTEIN: serine\/threonine-protein phosphatase PP1-alpha catalytic subunit\tK06269 PPP1C; serine\/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]" }, { "name":"103598453 PPP1CC; serine\/threonine-protein phosphatase PP1-gamma catalytic subunit isoform X1\tK06269 PPP1C; serine\/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]" }, { "name":"103607967 LOW QUALITY PROTEIN: serine\/threonine-protein phosphatase PP1-beta catalytic subunit-like\tK06269 PPP1C; serine\/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]" }, { "name":"103592730 PPP1R8; nuclear inhibitor of protein phosphatase 1\tK13216 PPP1R8; nuclear inhibitor of protein phosphatase 1 [EC:3.1.4.-]" }, { "name":"103585558 PRMT5; protein arginine N-methyltransferase 5 isoform X1\tK02516 PRMT5; type II protein arginine methyltransferase [EC:2.1.1.320]" }, { "name":"103593450 PRPF4B; serine\/threonine-protein kinase PRP4 homolog isoform X1\tK08827 PRPF4B; serine\/threonine-protein kinase PRP4 [EC:2.7.11.1]" }, { "name":"103587244 PRPF39; pre-mRNA-processing factor 39 isoform X1\tK13217 PRPF39; pre-mRNA-processing factor 39" }, { "name":"103594752 RAVER1; ribonucleoprotein PTB-binding 1\tK24999 RAVER1; ribonucleoprotein PTB-binding 1" }, { "name":"103607665 PTBP1; polypyrimidine tract-binding protein 1 isoform X1\tK13218 PTBP1; polypyrimidine tract-binding protein 1" }, { "name":"103592251 PTBP2; polypyrimidine tract-binding protein 2 isoform X1\tK14948 PTBP2; polypyrimidine tract-binding protein 2" }, { "name":"103601092 PTBP3; polypyrimidine tract-binding protein 3 isoform X1\tK17844 PTBP3; polypyrimidine tract-binding protein 3" }, { "name":"103607470 SRPK1; SRSF protein kinase 1 isoform X1\tK15409 SRPK1; serine\/threonine-protein kinase SRPK1 [EC:2.7.11.1]" }, { "name":"103586680 SRPK2; SRSF protein kinase 2\tK08831 SRPK2; serine\/threonine-protein kinase SRPK2 [EC:2.7.11.1]" }, { "name":"103591713 XRCC6; X-ray repair cross-complementing protein 6\tK10884 XRCC6; ATP-dependent DNA helicase 2 subunit 1" }, { "name":"103601532 WBP4; WW domain-binding protein 4\tK13220 WBP4; WW domain-binding protein 4" }, { "name":"103589875 WDR77; methylosome protein 50\tK13221 WDR77; methylosome protein 50" }, { "name":"103593405 CCNL1; cyclin-L1 isoform X1\tK23966 CCNL; cyclin L" }, { "name":"103594877 CCNL2; cyclin-L2\tK23966 CCNL; cyclin L" }, { "name":"103605346 DBR1; lariat debranching enzyme\tK18328 DBR1; lariat debranching enzyme [EC:3.1.-.-]" }, { "name":"103588799 CWF19L1; CWF19-like protein 1\tK24939 CWF19L1; CWF19-like protein 1" }, { "name":"103604581 CWF19-like protein 2\tK24940 CWF19L2; CWF19-like protein 2" }, { "name":"103606599 LOW QUALITY PROTEIN: CWF19-like protein 2\tK24940 CWF19L2; CWF19-like protein 2" }, { "name":"103590752 SAFB2; scaffold attachment factor B2 isoform X1\tK25092 SAFB; scaffold attachment factor B" }, { "name":"103590763 scaffold attachment factor B1-like\tK25092 SAFB; scaffold attachment factor B" }, { "name":"103600302 ARVCF; armadillo repeat protein deleted in velo-cardio-facial syndrome isoform X1\tK28154 ARVCF; splicing regulator ARVCF" }, { "name":"103602312 pre-mRNA-splicing factor CWC25 homolog\tK28450 CWC25; pre-mRNA-splicing factor CWC25" }, { "name":"103600174 CCDC94; coiled-coil domain-containing protein 94 isoform X1\tK28527 YJU2; splicing factor YJU2" } ] } ] } ] }, { "name":"Splicing related RNAs" } ] }