{
	"name":"hhu02044",
	"children":[
	{
		"name":"Type I secretion system",
		"children":[
		{
			"name":"alpha-Hemolysin\/cyclolysin transporter",
			"children":[
			{
				"name":"AR456_13350 type I secretion protein TolC\tK12340 tolC; outer membrane protein"
			},
			{
				"name":"AR456_18310 type I secretion protein TolC\tK12340 tolC; outer membrane protein"
			}
			]
		},
		{
			"name":"RTX toxin transporter",
			"children":[
			{
				"name":"AR456_13350 type I secretion protein TolC\tK12340 tolC; outer membrane protein"
			},
			{
				"name":"AR456_18310 type I secretion protein TolC\tK12340 tolC; outer membrane protein"
			}
			]
		},
		{
			"name":"Multiple protein transporter",
			"children":[
			{
				"name":"AR456_11670 peptidase\tK12536 hasD; ATP-binding cassette, subfamily C, type I secretion system permease\/ATPase"
			},
			{
				"name":"AR456_12245 type I secretion protein\tK12536 hasD; ATP-binding cassette, subfamily C, type I secretion system permease\/ATPase"
			},
			{
				"name":"AR456_18320 peptidase\tK12536 hasD; ATP-binding cassette, subfamily C, type I secretion system permease\/ATPase"
			},
			{
				"name":"AR456_11675 secretion protein HlyD\tK12537 hasE; membrane fusion protein, type I secretion system"
			},
			{
				"name":"AR456_12235 hemolysin secretion protein D\tK12537 hasE; membrane fusion protein, type I secretion system"
			},
			{
				"name":"AR456_18315 secretion protein HlyD\tK12537 hasE; membrane fusion protein, type I secretion system"
			},
			{
				"name":"AR456_13350 type I secretion protein TolC\tK12340 tolC; outer membrane protein"
			},
			{
				"name":"AR456_18310 type I secretion protein TolC\tK12340 tolC; outer membrane protein"
			}
			]
		},
		{
			"name":"Adhesin protein transporter",
			"children":[
			{
				"name":"AR456_09420 ABC transporter\tK12541 lapB; ATP-binding cassette, subfamily C, bacterial LapB"
			},
			{
				"name":"AR456_09425 secretion protein HylD\tK12542 lapC; membrane fusion protein, adhesin transport system"
			},
			{
				"name":"AR456_14440 hemolysin D\tK12542 lapC; membrane fusion protein, adhesin transport system"
			},
			{
				"name":"AR456_14450 hypothetical protein\tK12543 lapE; outer membrane protein, adhesin transport system"
			}
			]
		},
		{
			"name":"RaxAB-RaxC type I secretion system protein",
			"children":[
			{
				"name":"AR456_13350 type I secretion protein TolC\tK12340 tolC; outer membrane protein"
			},
			{
				"name":"AR456_18310 type I secretion protein TolC\tK12340 tolC; outer membrane protein"
			}
			]
		}
		]
	},
	{
		"name":"Type II secretion system",
		"children":[
		{
			"name":"General secretion pathway protein",
			"children":[
			{
				"name":"AR456_11160 methyltransferase\tK02654 pilD; leader peptidase (prepilin peptidase) \/ N-methyltransferase [EC:3.4.23.43 2.1.1.-]"
			}
			]
		},
		{
			"name":"Pilin secretion\/fimbrial assembly protein",
			"children":[
			{
				"name":"AR456_11475 hypothetical protein\tK02650 pilA; type IV pilus assembly protein PilA"
			},
			{
				"name":"AR456_11480 type IV-A pilus assembly ATPase PilB\tK02652 pilB; type IV pilus assembly protein PilB"
			},
			{
				"name":"AR456_11485 type II secretion system protein F\tK02653 pilC; type IV pilus assembly protein PilC"
			},
			{
				"name":"AR456_11160 methyltransferase\tK02654 pilD; leader peptidase (prepilin peptidase) \/ N-methyltransferase [EC:3.4.23.43 2.1.1.-]"
			},
			{
				"name":"AR456_02395 hypothetical protein\tK02655 pilE; type IV pilus assembly protein PilE"
			},
			{
				"name":"AR456_16340 hypothetical protein\tK02656 pilF; type IV pilus assembly protein PilF"
			},
			{
				"name":"AR456_03135 hypothetical protein\tK02662 pilM; type IV pilus assembly protein PilM"
			},
			{
				"name":"AR456_03140 hypothetical protein\tK02663 pilN; type IV pilus assembly protein PilN"
			},
			{
				"name":"AR456_03145 hypothetical protein\tK02664 pilO; type IV pilus assembly protein PilO"
			},
			{
				"name":"AR456_03150 hypothetical protein\tK02665 pilP; type IV pilus assembly protein PilP"
			},
			{
				"name":"AR456_03155 pilus assembly protein PilQ\tK02666 pilQ; type IV pilus assembly protein PilQ"
			},
			{
				"name":"AR456_02400 hypothetical protein\tK02671 pilV; type IV pilus assembly protein PilV"
			},
			{
				"name":"AR456_02415 hypothetical protein\tK08084 fimT; type IV fimbrial biogenesis protein FimT"
			}
			]
		},
		{
			"name":"Tight adherence (Tad) export apparatus",
			"children":[
			{
				"name":"AR456_17220 type II and III secretion system protein RhcC2\tK02280 cpaC; pilus assembly protein CpaC"
			},
			{
				"name":"AR456_17225 hypothetical protein\tK02281 cpaD; pilus assembly protein CpaD"
			}
			]
		},
		{
			"name":"Toxin co-regulated pilus biosynthesis protein"
		},
		{
			"name":"MSHA pilus biogenesis protein"
		},
		{
			"name":"Type IVa pilus homolog protein",
			"children":[
			{
				"name":"AR456_11160 methyltransferase\tK02654 pilD; leader peptidase (prepilin peptidase) \/ N-methyltransferase [EC:3.4.23.43 2.1.1.-]"
			},
			{
				"name":"AR456_19175 hypothetical protein\tK02221 yggT; YggT family protein"
			}
			]
		},
		{
			"name":"Archaeal flagellar protein"
		},
		{
			"name":"Competence-related DNA transformation transporter (DNA-T) core components",
			"children":[
			{
				"name":"AR456_11540 hypothetical protein\tK02237 comEA; competence protein ComEA"
			},
			{
				"name":"AR456_07575 hypothetical protein\tK02238 comEC; competence protein ComEC"
			}
			]
		},
		{
			"name":"Competence-related DNA transformation transporter (DNA-T) related proteins"
		}
		]
	},
	{
		"name":"Type III secretion system",
		"children":[
		{
			"name":"Type III secretion core apparatus",
			"children":[
			{
				"name":"AR456_17250 type III secretion protein\tK03222 yscJ; type III secretion protein J"
			},
			{
				"name":"AR456_17255 hypothetical protein\tK04054 yscK; type III secretion protein K"
			},
			{
				"name":"AR456_17260 hypothetical protein\tK03223 yscL; type III secretion protein L"
			},
			{
				"name":"AR456_17265 fliI; type III secretion apparatus H+-transporting two-sector ATPase\tK03224 yscN; ATP synthase in type III secretion protein N [EC:7.4.2.8]"
			},
			{
				"name":"AR456_17270 hypothetical protein\tK04056 yscO; type III secretion protein O"
			},
			{
				"name":"AR456_17275 hypothetical protein\tK03225 yscQ; type III secretion protein Q"
			},
			{
				"name":"AR456_17280 ssaR; type III secretion system protein SsaR\tK03226 yscR; type III secretion protein R"
			},
			{
				"name":"AR456_17285 type III secretion protein\tK03227 yscS; type III secretion protein S"
			},
			{
				"name":"AR456_17290 type III secretion protein\tK03228 yscT; type III secretion protein T"
			},
			{
				"name":"AR456_17295 translocation protein in type III secretion system, RhcU\tK03229 yscU; type III secretion protein U"
			},
			{
				"name":"AR456_17215 type III secretion protein\tK03230 yscV; type III secretion protein V"
			}
			]
		},
		{
			"name":"Type III secretion related proteins",
			"children":[
			{
				"name":"AR456_17210 hypothetical protein\tK04060 yscY; type III secretion protein Y"
			}
			]
		},
		{
			"name":"Flagellar export apparatus",
			"children":[
			{
				"name":"AR456_19940 flagellar biosynthesis protein FlhA\tK02400 flhA; flagellar biosynthesis protein FlhA"
			},
			{
				"name":"AR456_19935 flagellar biosynthetic protein FlhB\tK02401 flhB; flagellar biosynthesis protein FlhB"
			},
			{
				"name":"AR456_19875 flagellar protein FhlB\tK04061 flhB2; flagellar biosynthesis protein"
			},
			{
				"name":"AR456_19645 flagellar M-ring protein FliF\tK02409 fliF; flagellar M-ring protein FliF"
			},
			{
				"name":"AR456_19655 hypothetical protein\tK02411 fliH; flagellar assembly protein FliH"
			},
			{
				"name":"AR456_19660 flagellar protein export ATPase FliI\tK02412 fliI; flagellum-specific ATP synthase [EC:7.4.2.8]"
			},
			{
				"name":"AR456_19685 flagellar motor switch protein FliN\tK02417 fliN; flagellar motor switch protein FliN"
			},
			{
				"name":"AR456_19690 hypothetical protein\tK02418 fliO; flagellar protein FliO\/FliZ"
			},
			{
				"name":"AR456_19695 fliP; flagellar biosynthesis protein flip\tK02419 fliP; flagellar biosynthesis protein FliP"
			},
			{
				"name":"AR456_19700 flagellar biosynthetic protein FliQ\tK02420 fliQ; flagellar biosynthesis protein FliQ"
			},
			{
				"name":"AR456_19705 flagellar biosynthetic protein FliR\tK02421 fliR; flagellar biosynthesis protein FliR"
			}
			]
		}
		]
	},
	{
		"name":"Type IV secretion system",
		"children":[
		{
			"name":"Conjugal DNA-protein transfer (VirB\/D) protein"
		},
		{
			"name":"DNA uptake competence system protein"
		},
		{
			"name":"Conjugal transfer pilus assembly protein",
			"children":[
			{
				"name":"AR456_18995 hypothetical protein\tK12055 K12055; chromosome partitioning related protein ParA"
			},
			{
				"name":"AR456_18565 hypothetical protein\tK12070 traI; conjugal transfer pilus assembly protein TraI"
			},
			{
				"name":"AR456_17390 protein-disulfide isomerase\tK03981 dsbC; thiol:disulfide interchange protein DsbC [EC:5.3.4.1]"
			},
			{
				"name":"AR456_18770 hypothetical protein\tK03981 dsbC; thiol:disulfide interchange protein DsbC [EC:5.3.4.1]"
			}
			]
		},
		{
			"name":"Pertussis toxin exporter"
		},
		{
			"name":"Cag pathogenicity island (PAI) protein"
		},
		{
			"name":"Icm\/Dot secretion system protein"
		},
		{
			"name":"Trb secretion system protein",
			"children":[
			{
				"name":"AR456_14745 conjugal transfer protein TrbJ\tK20266 trbJ; type IV secretion system protein TrbJ"
			},
			{
				"name":"AR456_14735 conjugal transfer protein TrbL\tK07344 trbL; type IV secretion system protein TrbL"
			}
			]
		}
		]
	},
	{
		"name":"Type V secretion system",
		"children":[
		{
			"name":"Autotransporter-1 (AT-1) family"
		},
		{
			"name":"Autotransporter-2 (AT-2) family"
		},
		{
			"name":"Two-partner secretion (TPS) family"
		}
		]
	},
	{
		"name":"Type VI secretion system",
		"children":[
		{
			"name":"Imp\/Vas secretion system core components",
			"children":[
			{
				"name":"AR456_18170 hypothetical protein\tK11891 impL; type VI secretion system protein ImpL"
			},
			{
				"name":"AR456_18180 hypothetical protein\tK11891 impL; type VI secretion system protein ImpL"
			},
			{
				"name":"AR456_18185 type VI secretion system protein ImpK\tK11892 impK; type VI secretion system protein ImpK"
			},
			{
				"name":"AR456_18190 type VI secretion protein\tK11893 impJ; type VI secretion system protein ImpJ"
			},
			{
				"name":"AR456_18205 type VI secretion system protein\tK11895 impH; type VI secretion system protein ImpH"
			},
			{
				"name":"AR456_18210 type VI secretion system protein\tK11896 impG; type VI secretion system protein ImpG"
			},
			{
				"name":"AR456_18215 type VI secretion protein\tK11897 impF; type VI secretion system protein ImpF"
			},
			{
				"name":"AR456_18220 EvpB family type VI secretion protein\tK11900 impC; type VI secretion system protein ImpC"
			},
			{
				"name":"AR456_18225 type VI secretion protein\tK11901 impB; type VI secretion system protein ImpB"
			},
			{
				"name":"AR456_18160 ImpA-like protein\tK11902 impA; type VI secretion system protein ImpA"
			},
			{
				"name":"AR456_18165 fimbrial protein\tK11903 hcp; type VI secretion system secreted protein Hcp"
			},
			{
				"name":"AR456_06740 type IV secretion protein Rhs\tK11904 vgrG; type VI secretion system secreted protein VgrG"
			},
			{
				"name":"AR456_09185 type IV secretion protein Rhs\tK11904 vgrG; type VI secretion system secreted protein VgrG"
			},
			{
				"name":"AR456_18150 type IV secretion protein Rhs\tK11904 vgrG; type VI secretion system secreted protein VgrG"
			},
			{
				"name":"AR456_18195 hypothetical protein\tK11906 vasD; type VI secretion system protein VasD"
			},
			{
				"name":"AR456_18200 ClpV1 family T6SS ATPase\tK11907 vasG; type VI secretion system protein VasG"
			}
			]
		},
		{
			"name":"Imp\/Vas secretion system related proteins",
			"children":[
			{
				"name":"AR456_18175 hypothetical protein\tK11890 impM; type VI secretion system protein ImpM"
			}
			]
		}
		]
	},
	{
		"name":"Type VII secretion system",
		"children":[
		{
			"name":"ESX secretion system protein"
		}
		]
	},
	{
		"name":"Chaperone-usher system",
		"children":[
		{
			"name":"Type 1 pilus assembly protein",
			"children":[
			{
				"name":"AR456_08980 hypothetical protein\tK07345 fimA; major type 1 subunit fimbrin (pilin)"
			},
			{
				"name":"AR456_08995 hypothetical protein\tK07345 fimA; major type 1 subunit fimbrin (pilin)"
			},
			{
				"name":"AR456_09095 pilus assembly protein\tK07346 fimC; fimbrial chaperone protein"
			},
			{
				"name":"AR456_02765 hypothetical protein\tK07347 fimD; outer membrane usher protein"
			},
			{
				"name":"AR456_08990 hypothetical protein\tK07347 fimD; outer membrane usher protein"
			},
			{
				"name":"AR456_09100 fimbrial assembly protein\tK07347 fimD; outer membrane usher protein"
			},
			{
				"name":"AR456_09090 spore coat protein U\tK27078 cupE; spore coat protein U domain-containing protein, fimbrial subunit CupE1\/2\/3\/6"
			},
			{
				"name":"AR456_09105 hypothetical protein\tK27078 cupE; spore coat protein U domain-containing protein, fimbrial subunit CupE1\/2\/3\/6"
			}
			]
		},
		{
			"name":"P pilus assembly protein"
		},
		{
			"name":"Mat\/Ecp fimbriae assembly protein"
		}
		]
	},
	{
		"name":"Extracellular nucleation-precipitation pathway",
		"children":[
		{
			"name":"Curli assembly protein"
		}
		]
	},
	{
		"name":"Sec (secretion) system",
		"children":[
		{
			"name":"Prokaryotic Sec-SRP core components",
			"children":[
			{
				"name":"AR456_07535 secA; preprotein translocase subunit SecA\tK03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]"
			},
			{
				"name":"AR456_00175 preprotein translocase subunit SecB\tK03071 secB; preprotein translocase subunit SecB"
			},
			{
				"name":"AR456_16280 secD; preprotein translocase subunit SecD\tK03072 secD; preprotein translocase subunit SecD"
			},
			{
				"name":"AR456_01630 preprotein translocase subunit SecE\tK03073 secE; preprotein translocase subunit SecE"
			},
			{
				"name":"AR456_16285 preprotein translocase subunit SecF\tK03074 secF; preprotein translocase subunit SecF"
			},
			{
				"name":"AR456_01250 preprotein translocase subunit SecG\tK03075 secG; preprotein translocase subunit SecG"
			},
			{
				"name":"AR456_01795 secY; preprotein translocase subunit SecY\tK03076 secY; preprotein translocase subunit SecY"
			},
			{
				"name":"AR456_17420 RNA-binding protein\tK03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]"
			},
			{
				"name":"AR456_02590 signal recognition particle-docking protein FtsY\tK03110 ftsY; fused signal recognition particle receptor"
			},
			{
				"name":"AR456_16275 preprotein translocase subunit YajC\tK03210 yajC; preprotein translocase subunit YajC"
			},
			{
				"name":"AR456_20725 insertase\tK03217 yidC; YidC\/Oxa1 family membrane protein insertase"
			}
			]
		},
		{
			"name":"Prokaryotic Sec-SRP related proteins"
		},
		{
			"name":"Eukaryotic Sec-SRP protein",
			"children":[
			{
				"name":"AR456_17420 RNA-binding protein\tK03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]"
			}
			]
		}
		]
	},
	{
		"name":"Twin-arginine translocation (Tat) system",
		"children":[
		{
			"name":"Twin-arginine translocation (Tat) pathway protein",
			"children":[
			{
				"name":"AR456_02980 preprotein translocase subunit TatA\tK03116 tatA; sec-independent protein translocase protein TatA"
			},
			{
				"name":"AR456_02970 twin-arginine protein translocation system subunit TatC\tK03118 tatC; sec-independent protein translocase protein TatC"
			}
			]
		}
		]
	}
	]
}
