{
	"name":"hmg03051",
	"children":[
	{
		"name":"Eukaryotic proteasome",
		"children":[
		{
			"name":"Core particles (20S proteasome)",
			"children":[
			{
				"name":"alpha type subunits",
				"children":[
				{
					"name":"100207675 LOC100207675; proteasome subunit alpha type-6 isoform X1\tK02730 PSMA6; 20S proteasome subunit alpha 1 [EC:3.4.25.1]"
				},
				{
					"name":"100209532 LOC100209532; proteasome subunit alpha type-2 isoform X1\tK02726 PSMA2; 20S proteasome subunit alpha 2 [EC:3.4.25.1]"
				},
				{
					"name":"100203275 LOC100203275; proteasome subunit alpha type-4\tK02728 PSMA4; 20S proteasome subunit alpha 3 [EC:3.4.25.1]"
				},
				{
					"name":"100210370 LOC100210370; proteasome subunit alpha type-7-like\tK02731 PSMA7; 20S proteasome subunit alpha 4 [EC:3.4.25.1]"
				},
				{
					"name":"100207195 LOC100207195; proteasome subunit alpha type-5 isoform X1\tK02729 PSMA5; 20S proteasome subunit alpha 5 [EC:3.4.25.1]"
				},
				{
					"name":"100211967 LOC100211967; proteasome subunit alpha type-1 isoform X1\tK02725 PSMA1; 20S proteasome subunit alpha 6 [EC:3.4.25.1]"
				},
				{
					"name":"100209384 LOC100209384; proteasome subunit alpha type-3\tK02727 PSMA3; 20S proteasome subunit alpha 7 [EC:3.4.25.1]"
				}
				]
			},
			{
				"name":"beta type subunits",
				"children":[
				{
					"name":"100197304 LOC100197304; proteasome subunit beta type-6\tK02738 PSMB6; 20S proteasome subunit beta 1 [EC:3.4.25.1]"
				},
				{
					"name":"100204701 LOC100204701; proteasome subunit beta type-7 isoform X1\tK02739 PSMB7; 20S proteasome subunit beta 2 [EC:3.4.25.1]"
				},
				{
					"name":"100209400 LOC100209400; proteasome subunit beta type-3 isoform X1\tK02735 PSMB3; 20S proteasome subunit beta 3 [EC:3.4.25.1]"
				},
				{
					"name":"100200751 LOC100200751; proteasome subunit beta type-5\tK02737 PSMB5; 20S proteasome subunit beta 5 [EC:3.4.25.1]"
				},
				{
					"name":"100198899 LOC100198899; proteasome subunit beta type-1-B\tK02732 PSMB1; 20S proteasome subunit beta 6 [EC:3.4.25.1]"
				},
				{
					"name":"100204898 LOC100204898; proteasome subunit beta type-4 isoform X1\tK02736 PSMB4; 20S proteasome subunit beta 7 [EC:3.4.25.1]"
				}
				]
			}
			]
		},
		{
			"name":"Regulatory particles",
			"children":[
			{
				"name":"PA700 (19S proteasome)",
				"children":[
				{
					"name":"ATPase subunits",
					"children":[
					{
						"name":"100208062 LOC100208062; 26S proteasome regulatory subunit 7 isoform X1\tK03061 PSMC2; 26S proteasome regulatory subunit T1"
					},
					{
						"name":"100209561 LOC100209561; 26S proteasome regulatory subunit 4 isoform X1\tK03062 PSMC1; 26S proteasome regulatory subunit T2"
					},
					{
						"name":"100212113 LOC100212113; 26S proteasome regulatory subunit 6B isoform X1\tK03063 PSMC4; 26S proteasome regulatory subunit T3"
					},
					{
						"name":"100210600 LOC100210600; 26S proteasome regulatory subunit 10B isoform X1\tK03064 PSMC6; 26S proteasome regulatory subunit T4"
					},
					{
						"name":"100210427 LOC100210427; 26S proteasome regulatory subunit 6A-B\tK03065 PSMC3; 26S proteasome regulatory subunit T5"
					},
					{
						"name":"100213117 LOC100213117; 26S proteasome regulatory subunit 8 isoform X1\tK03066 PSMC5; 26S proteasome regulatory subunit T6"
					}
					]
				},
				{
					"name":"non-ATPase subunits",
					"children":[
					{
						"name":"100214860 LOC100214860; 26S proteasome non-ATPase regulatory subunit 2\tK03028 PSMD2; 26S proteasome regulatory subunit N1"
					},
					{
						"name":"100199064 LOC100199064; 26S proteasome non-ATPase regulatory subunit 1 isoform X1\tK03032 PSMD1; 26S proteasome regulatory subunit N2"
					},
					{
						"name":"100205064 LOC100205064; 26S proteasome non-ATPase regulatory subunit 3 isoform X1\tK03033 PSMD3; 26S proteasome regulatory subunit N3"
					},
					{
						"name":"101234866 LOC101234866; 26S proteasome non-ATPase regulatory subunit 9 isoform X1\tK06693 PSMD9; 26S proteasome regulatory subunit N4"
					},
					{
						"name":"100211225 LOC100211225; 26S proteasome non-ATPase regulatory subunit 12 isoform X1\tK03035 PSMD12; 26S proteasome regulatory subunit N5"
					},
					{
						"name":"100212727 LOC100212727; 26S proteasome non-ATPase regulatory subunit 11 isoform X1\tK03036 PSMD11; 26S proteasome regulatory subunit N6"
					},
					{
						"name":"100199711 LOC100199711; 26S proteasome non-ATPase regulatory subunit 6 isoform X1\tK03037 PSMD6; 26S proteasome regulatory subunit N7"
					},
					{
						"name":"100202285 LOC100202285; 26S proteasome non-ATPase regulatory subunit 7\tK03038 PSMD7; 26S proteasome regulatory subunit N8"
					},
					{
						"name":"100211422 LOC100211422; 26S proteasome non-ATPase regulatory subunit 13 isoform X1\tK03039 PSMD13; 26S proteasome regulatory subunit N9"
					},
					{
						"name":"100214857 LOC100214857; 26S proteasome non-ATPase regulatory subunit 4\tK03029 PSMD4; 26S proteasome regulatory subunit N10"
					},
					{
						"name":"100205738 LOC100205738; 26S proteasome non-ATPase regulatory subunit 14 isoform X1\tK03030 PSMD14; 26S proteasome regulatory subunit N11"
					},
					{
						"name":"100207390 LOC100207390; 26S proteasome non-ATPase regulatory subunit 8 isoform X1\tK03031 PSMD8; 26S proteasome regulatory subunit N12"
					},
					{
						"name":"100210358 LOC100210358; proteasomal ubiquitin receptor ADRM1-B isoform X1\tK06691 RPN13; 26S proteasome regulatory subunit N13"
					},
					{
						"name":"100212313 LOC100212313; 26S proteasome complex subunit SEM1 isoform X1\tK10881 SHFM1; 26 proteasome complex subunit DSS1"
					},
					{
						"name":"100203771 LOC100203771; 26S proteasome non-ATPase regulatory subunit 5\tK06692 PSMD5; 26S proteasome non-ATPase regulatory subunit 5"
					},
					{
						"name":"100201316 LOC100201316; 26S proteasome non-ATPase regulatory subunit 10 isoform X1\tK06694 PSMD10; 26S proteasome non-ATPase regulatory subunit 10"
					}
					]
				}
				]
			},
			{
				"name":"PA28 (11S REG)"
			},
			{
				"name":"PA200",
				"children":[
				{
					"name":"101234870 LOC101234870; proteasome activator complex subunit 4A isoform X1\tK06699 PSME4; proteasome activator subunit 4"
				}
				]
			},
			{
				"name":"PI31"
			}
			]
		},
		{
			"name":"Assembling factors",
			"children":[
			{
				"name":"Assembling chaperones",
				"children":[
				{
					"name":"100202327 LOC100202327; proteasome maturation protein\tK11599 POMP; proteasome maturation protein"
				},
				{
					"name":"105844376 LOC105844376; proteasome assembly chaperone 1\tK11875 PSMG1; proteasome assembly chaperone 1"
				},
				{
					"name":"100211450 LOC100211450; proteasome assembly chaperone 2\tK11876 PSMG2; proteasome assembly chaperone 2"
				}
				]
			},
			{
				"name":"Other assembling factors",
				"children":[
				{
					"name":"100200892 LOC100200892; eukaryotic translation initiation factor 3 subunit E\tK03250 EIF3E; translation initiation factor 3 subunit E"
				},
				{
					"name":"100202286 LOC100202286; heat shock 70 kDa protein-like\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
				},
				{
					"name":"100203304 LOC100203304; heat shock 70 kDa protein\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
				},
				{
					"name":"105844776 LOC105844776; heat shock 70 kDa protein-like\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
				},
				{
					"name":"124807918 LOC124807918; heat shock 70 kDa protein-like isoform X1\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
				},
				{
					"name":"124807919 LOC124807919; heat shock 70 kDa protein-like isoform X1\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
				},
				{
					"name":"124807971 LOC124807971; heat shock 70 kDa protein-like\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
				},
				{
					"name":"124807972 LOC124807972; heat shock 70 kDa protein-like\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
				},
				{
					"name":"124816626 LOC124816626; heat shock 70 kDa protein-like\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
				},
				{
					"name":"124816818 LOC124816818; heat shock 70 kDa protein-like\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
				},
				{
					"name":"100199389 LOC100199389; heat shock protein HSP 90-alpha\tK04079 HSP90A; molecular chaperone HtpG"
				},
				{
					"name":"101235897 LOC101235897; heat shock protein HSP 90-alpha\tK04079 HSP90A; molecular chaperone HtpG"
				},
				{
					"name":"100211542 LOC100211542; RNA-binding protein NOB1\tK11883 NOB1; RNA-binding protein NOB1"
				},
				{
					"name":"105847006 LOC105847006; RNA-binding protein pno1 isoform X1\tK11884 PNO1; RNA-binding protein PNO1"
				}
				]
			}
			]
		},
		{
			"name":"Proteasome interacting proteins (PIPs)",
			"children":[
			{
				"name":"UBL-UBA shuttle proteins",
				"children":[
				{
					"name":"100201209 LOC100201209; UV excision repair protein RAD23 homolog B isoform X1\tK10839 RAD23; UV excision repair protein RAD23"
				},
				{
					"name":"100211830 LOC100211830; ubiquilin-1 isoform X1\tK04523 UBQLN; ubiquilin"
				},
				{
					"name":"100203870 LOC100203870; protein DDI1 homolog 2\tK11885 DDI; DNA damage-inducible protein [EC:3.4.23.-]"
				}
				]
			},
			{
				"name":"Other PIPs",
				"children":[
				{
					"name":"101239838 LOC101239838; proteasome adapter and scaffold protein ECM29 isoform X1\tK11886 ECM29; proteasome component ECM29"
				},
				{
					"name":"101238741 LOC101238741; proteasomal ATPase-associated factor 1 isoform X2\tK11887 PAAF1; proteasomal ATPase-associated factor 1"
				},
				{
					"name":"100197364 LOC100197364; homologous-pairing protein 2 homolog\tK06695 PSMC3IP; 26S proteasome regulatory subunit, ATPase 3, interacting protein"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic proteasome",
		"children":[
		{
			"name":"Core particles (20S proteasome)"
		},
		{
			"name":"Bacterial regulatory particles"
		},
		{
			"name":"Archaeal regulatory particles"
		}
		]
	}
	]
}