{
	"name":"hpyb03009",
	"children":[
	{
		"name":"Eukaryotic type",
		"children":[
		{
			"name":"Sno RNPs",
			"children":[
			{
				"name":"Box C\/D snoRNPs"
			},
			{
				"name":"Box H\/ACA snoRNPs"
			}
			]
		},
		{
			"name":"90S particles",
			"children":[
			{
				"name":"U3 small nucleolar RNA-associated proteins"
			},
			{
				"name":"Helicases"
			},
			{
				"name":"GTPase"
			},
			{
				"name":"RNase",
				"children":[
				{
					"name":"HPOKI102_03700 ribonuclease III\tK03685 rnc; ribonuclease III [EC:3.1.26.3]"
				}
				]
			},
			{
				"name":"Kinase"
			},
			{
				"name":"Other 90S particles"
			}
			]
		},
		{
			"name":"Pre-40S particles",
			"children":[
			{
				"name":"Kinases"
			},
			{
				"name":"Export and cytoplasmic maturation factors"
			},
			{
				"name":"Other pre-40S particles"
			}
			]
		},
		{
			"name":"Pre-60S particles",
			"children":[
			{
				"name":"Helicases"
			},
			{
				"name":"GTPases"
			},
			{
				"name":"RNases",
				"children":[
				{
					"name":"RNase MRP"
				}
				]
			},
			{
				"name":"Kinases"
			},
			{
				"name":"Export and cytoplasmic maturation factors"
			},
			{
				"name":"55LCC heterohexameric ATPase complex"
			},
			{
				"name":"5-FMC complex"
			},
			{
				"name":"Ribosome quality control proteins"
			},
			{
				"name":"Other pre-60S particles"
			}
			]
		},
		{
			"name":"Other ribosome biogenesis factors",
			"children":[
			{
				"name":"HPOKI102_04440 GTPase Era\tK03595 era; GTPase"
			},
			{
				"name":"HPOKI102_01820 GTPase CgtA\tK03979 obgE; GTPase [EC:3.6.5.-]"
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic type",
		"children":[
		{
			"name":"Sno RNPs",
			"children":[
			{
				"name":"Box C\/D snoRNPs"
			},
			{
				"name":"Box H\/ACA snoRNPs"
			}
			]
		},
		{
			"name":"rRNA transcription factors",
			"children":[
			{
				"name":"HPOKI102_07655 transcription elongation factor NusA\tK02600 nusA; transcription termination\/antitermination protein NusA"
			},
			{
				"name":"HPOKI102_00005 transcription antitermination protein NusB\tK03625 nusB; transcription antitermination protein NusB"
			},
			{
				"name":"HPOKI102_06345 nusG; transcription antitermination protein NusG\tK02601 nusG; transcription termination\/antitermination protein NusG"
			}
			]
		},
		{
			"name":"rRNA modification factors",
			"children":[
			{
				"name":"16S rRNA modification factors",
				"children":[
				{
					"name":"HPOKI102_07205 16S rRNA methyltransferase\tK02528 ksgA; 16S rRNA (adenine1518-N6\/adenine1519-N6)-dimethyltransferase [EC:2.1.1.182]"
				},
				{
					"name":"HPOKI102_05665 16S rRNA methyltransferase\tK09761 rsmE; 16S rRNA (uracil1498-N3)-methyltransferase [EC:2.1.1.193]"
				},
				{
					"name":"HPOKI102_02225 16S rRNA methyltransferase\tK03501 gidB; 16S rRNA (guanine527-N7)-methyltransferase [EC:2.1.1.170]"
				},
				{
					"name":"HPOKI102_03495 16S rRNA methyltransferase\tK03438 mraW; 16S rRNA (cytosine1402-N4)-methyltransferase [EC:2.1.1.199]"
				},
				{
					"name":"HPOKI102_04255 16S rRNA methyltransferase\tK07056 rsmI; 16S rRNA (cytidine1402-2'-O)-methyltransferase [EC:2.1.1.198]"
				},
				{
					"name":"HPOKI102_02105 hemolysin\tK06442 tlyA; 23S rRNA (cytidine1920-2'-O)\/16S rRNA (cytidine1409-2'-O)-methyltransferase [EC:2.1.1.226 2.1.1.227]"
				}
				]
			},
			{
				"name":"23S rRNA modification factors",
				"children":[
				{
					"name":"HPOKI102_04250 RNA methyltransferase\tK03218 rlmB; 23S rRNA (guanosine2251-2'-O)-methyltransferase [EC:2.1.1.185]"
				},
				{
					"name":"HPOKI102_04970 50S rRNA methyltransferase\tK00783 rlmH; 23S rRNA (pseudouridine1915-N3)-methyltransferase [EC:2.1.1.177]"
				},
				{
					"name":"HPOKI102_07190 50S rRNA methyltransferase\tK06941 rlmN; 23S rRNA (adenine2503-C2)-methyltransferase [EC:2.1.1.192]"
				},
				{
					"name":"HPOKI102_02105 hemolysin\tK06442 tlyA; 23S rRNA (cytidine1920-2'-O)\/16S rRNA (cytidine1409-2'-O)-methyltransferase [EC:2.1.1.226 2.1.1.227]"
				},
				{
					"name":"HPOKI102_07375 RNA pseudouridine synthase\tK06178 rluB; 23S rRNA pseudouridine2605 synthase [EC:5.4.99.22]"
				},
				{
					"name":"HPOKI102_05005 RNA pseudouridine synthase\tK06179 rluC; 23S rRNA pseudouridine955\/2504\/2580 synthase [EC:5.4.99.24]"
				},
				{
					"name":"HPOKI102_02015 RNA pseudouridine synthase\tK06180 rluD; 23S rRNA pseudouridine1911\/1915\/1917 synthase [EC:5.4.99.23]"
				},
				{
					"name":"HPOKI102_03320 ribose 1,5-bisphosphokinase\tK06180 rluD; 23S rRNA pseudouridine1911\/1915\/1917 synthase [EC:5.4.99.23]"
				}
				]
			}
			]
		},
		{
			"name":"ribosomal protein modification factors",
			"children":[
			{
				"name":"HPOKI102_06060 rimM; 16S rRNA-processing protein RimM\tK02860 rimM; 16S rRNA processing protein RimM"
			},
			{
				"name":"HPOKI102_03385 ribosomal protein S12 methylthiotransferase\tK14441 rimO; ribosomal protein S12 methylthiotransferase [EC:2.8.4.4]"
			},
			{
				"name":"HPOKI102_02195 ribosomal protein L11 methyltransferase\tK02687 prmA; ribosomal protein L11 methyltransferase [EC:2.1.1.-]"
			}
			]
		},
		{
			"name":"rRNA processing factors",
			"children":[
			{
				"name":"HPOKI102_03700 ribonuclease III\tK03685 rnc; ribonuclease III [EC:3.1.26.3]"
			},
			{
				"name":"HPOKI102_01990 Holliday junction resolvase\tK07447 ruvX; putative pre-16S rRNA nuclease [EC:3.1.-.-]"
			}
			]
		},
		{
			"name":"rRNA helicases",
			"children":[
			{
				"name":"HPOKI102_01540 DEAD\/DEAH box helicase\tK05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7]"
			}
			]
		},
		{
			"name":"GTPases",
			"children":[
			{
				"name":"HPOKI102_04440 GTPase Era\tK03595 era; GTPase"
			},
			{
				"name":"HPOKI102_02860 GTPase Der\tK03977 engA; GTPase"
			},
			{
				"name":"HPOKI102_01820 GTPase CgtA\tK03979 obgE; GTPase [EC:3.6.5.-]"
			}
			]
		},
		{
			"name":"Other maturation factors",
			"children":[
			{
				"name":"HPOKI102_03165 penta-phosphate guanosine-3'-pyrophosphohydrolase\tK01139 spoT; GTP diphosphokinase \/ guanosine-3',5'-bis(diphosphate) 3'-diphosphatase [EC:2.7.6.5 3.1.7.2]"
			},
			{
				"name":"HPOKI102_02305 ribosome-binding factor A\tK02834 rbfA; ribosome-binding factor A"
			},
			{
				"name":"HPOKI102_02310 ribosome maturation protein RimP\tK09748 rimP; ribosome maturation factor RimP"
			},
			{
				"name":"HPOKI102_00290 hypothetical protein\tK09710 ybeB; ribosome-associated protein"
			},
			{
				"name":"HPOKI102_06125 heat-shock protein\tK07042 ybeY; probable rRNA maturation factor"
			},
			{
				"name":"HPOKI102_04170 ychF; GTP-binding protein YchF\tK06942 ychF; ribosome-binding ATPase"
			}
			]
		}
		]
	},
	{
		"name":"Related small nucleolar RNAs",
		"children":[
		{
			"name":"Box C\/D snoRNAs",
			"children":[
			{
				"name":"SnoRNAs involved in processing reactions"
			},
			{
				"name":"SnoRNAs act as guides for 2'-O-ribose methylation"
			}
			]
		},
		{
			"name":"Box H\/ACA snoRNAs",
			"children":[
			{
				"name":"SnoRNAs involved in processing reactions"
			},
			{
				"name":"SnoRNAs act as guides for pseudouridynation"
			}
			]
		},
		{
			"name":"Other snoRNA"
		}
		]
	}
	]
}
