{
	"name":"hpyd03016",
	"children":[
	{
		"name":"Eukaryotic type",
		"children":[
		{
			"name":"5'processing factors",
			"children":[
			{
				"name":"Ribonucrease P"
			}
			]
		},
		{
			"name":"3'processing and CCA adding factors",
			"children":[
			{
				"name":"3'processing factors"
			},
			{
				"name":"CCA adding factors"
			}
			]
		},
		{
			"name":"tRNA spricing factors",
			"children":[
			{
				"name":"tRNA splicing endonuclease complex"
			},
			{
				"name":"tRNA splicing ligase complex"
			},
			{
				"name":"Other tRNA splicing factors"
			}
			]
		},
		{
			"name":"tRNA transport factors",
			"children":[
			{
				"name":"tRNA export factors"
			},
			{
				"name":"tRNA import factors"
			}
			]
		},
		{
			"name":"Aminoacyl-tRNA synthetases (AARSs)",
			"children":[
			{
				"name":"Multi-aminoacyl-tRNA synthetase complex (MSC)",
				"children":[
				{
					"name":"HPOKI128_02365 glutamyl-tRNA synthetase\tK01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]"
				},
				{
					"name":"HPOKI128_01310 prolyl-tRNA synthetase\tK01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]"
				},
				{
					"name":"HPOKI128_06905 isoleucyl-tRNA synthase\tK01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]"
				},
				{
					"name":"HPOKI128_00230 leucyl-tRNA synthetase\tK01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]"
				},
				{
					"name":"HPOKI128_04850 methionyl-tRNA synthetase\tK01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]"
				},
				{
					"name":"HPOKI128_01700 arginyl-tRNA synthetase\tK01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]"
				},
				{
					"name":"HPOKI128_01005 lysyl-tRNA synthetase\tK04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]"
				},
				{
					"name":"HPOKI128_02940 aspartyl-tRNA synthetase\tK01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]"
				}
				]
			},
			{
				"name":"Other AARSs",
				"children":[
				{
					"name":"HPOKI128_05975 alanyl-tRNA synthetase\tK01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]"
				},
				{
					"name":"HPOKI128_00690 threonyl-tRNA synthetase\tK01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]"
				},
				{
					"name":"HPOKI128_06595 seryl-tRNA synthetase\tK01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]"
				},
				{
					"name":"HPOKI128_04240 cysteinyl-tRNA synthetase\tK01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]"
				},
				{
					"name":"HPOKI128_05470 valyl-tRNA synthetase\tK01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]"
				},
				{
					"name":"HPOKI128_05690 histidyl-tRNA synthase\tK01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]"
				},
				{
					"name":"HPOKI128_04940 phenylalanyl-tRNA synthetase subunit alpha\tK01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]"
				},
				{
					"name":"HPOKI128_04945 phenylalanyl-tRNA synthetase subunit beta\tK01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]"
				},
				{
					"name":"HPOKI128_03695 tyrosyl-tRNA synthetase\tK01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]"
				},
				{
					"name":"HPOKI128_07650 tryptophanyl-tRNA synthetase\tK01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]"
				}
				]
			},
			{
				"name":"Trans-editing factors"
			},
			{
				"name":"AARS associated factors",
				"children":[
				{
					"name":"HPOKI128_04930 hypothetical protein\tK02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]"
				}
				]
			}
			]
		},
		{
			"name":"tRNA modification factors",
			"children":[
			{
				"name":"Deaminases"
			},
			{
				"name":"Dihydorouridine synthases"
			},
			{
				"name":"Methylthiotransferase",
				"children":[
				{
					"name":"HPOKI128_01470 (dimethylallyl)adenosine tRNA methylthiotransferase\tK06168 CDK5RAP1; tRNA-2-methylthio-N6-dimethylallyladenosine synthase [EC:2.8.4.3]"
				},
				{
					"name":"HPOKI128_01550 radical SAM protein\tK15865 CDKAL1; threonylcarbamoyladenosine tRNA methylthiotransferase [EC:2.8.4.5]"
				}
				]
			},
			{
				"name":"Methyltransferases",
				"children":[
				{
					"name":"HPOKI128_03555 tRNA (guanine-N(7)-)-methyltransferase\tK03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33]"
				}
				]
			},
			{
				"name":"Psudouridine synthases",
				"children":[
				{
					"name":"HPOKI128_05150 tRNA pseudouridine synthase A\tK06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]"
				},
				{
					"name":"HPOKI128_04435 tRNA pseudouridine synthase D\tK06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]"
				}
				]
			},
			{
				"name":"Thiolation factors",
				"children":[
				{
					"name":"HPOKI128_01200 cysteine desulfarase\tK04487 iscS; cysteine desulfurase [EC:2.8.1.7]"
				}
				]
			},
			{
				"name":"KEOPS\/EKC complex"
			},
			{
				"name":"Elongator complex"
			},
			{
				"name":"Elongator related proteins"
			},
			{
				"name":"Other tRNA modification factors",
				"children":[
				{
					"name":"HPOKI128_06945 tRNA delta(2)-isopentenylpyrophosphate transferase\tK00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]"
				},
				{
					"name":"HPOKI128_06740 tRNA modification GTPase TrmE\tK03650 mnmE; tRNA modification GTPase [EC:3.6.-.-]"
				},
				{
					"name":"HPOKI128_01165 tRNA uridine 5-carboxymethylaminomethyl modification protein\tK03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme"
				}
				]
			}
			]
		},
		{
			"name":"tRNA degradation factors",
			"children":[
			{
				"name":"TRAMP complex"
			},
			{
				"name":"Rapid tRNA decay (RTD) pathway factors"
			},
			{
				"name":"Other tRNA degradation factors"
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic type",
		"children":[
		{
			"name":"5'processing factors",
			"children":[
			{
				"name":"Ribonucrease P",
				"children":[
				{
					"name":"HPOKI128_06760 ribonuclease P\tK03536 rnpA; ribonuclease P protein component [EC:3.1.26.5]"
				},
				{
					"name":"HPOKI128_02840 bacterial RNase P\tK01978 rnpB; RNase P catalytic RNA component"
				}
				]
			}
			]
		},
		{
			"name":"3'processing and CCA adding factors",
			"children":[
			{
				"name":"3'processing factors"
			},
			{
				"name":"CCA adding factors"
			}
			]
		},
		{
			"name":"tRNA spricing factors",
			"children":[
			{
				"name":"tRNA splicing endonucleases"
			},
			{
				"name":"tRNA splicing ligases"
			},
			{
				"name":"Other tRNA splicing factors"
			}
			]
		},
		{
			"name":"tRNA transport factors",
			"children":[
			{
				"name":"tRNA export factors"
			}
			]
		},
		{
			"name":"Aminoacyl-tRNA synthetases (AARSs)",
			"children":[
			{
				"name":"Multi-aminoacyl-tRNA synthetase complex (MSC)",
				"children":[
				{
					"name":"HPOKI128_00230 leucyl-tRNA synthetase\tK01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]"
				},
				{
					"name":"HPOKI128_01310 prolyl-tRNA synthetase\tK01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]"
				}
				]
			},
			{
				"name":"Other AARSs",
				"children":[
				{
					"name":"HPOKI128_03695 tyrosyl-tRNA synthetase\tK01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]"
				},
				{
					"name":"HPOKI128_07650 tryptophanyl-tRNA synthetase\tK01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]"
				},
				{
					"name":"HPOKI128_00690 threonyl-tRNA synthetase\tK01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]"
				},
				{
					"name":"HPOKI128_06905 isoleucyl-tRNA synthase\tK01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]"
				},
				{
					"name":"HPOKI128_01005 lysyl-tRNA synthetase\tK04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]"
				},
				{
					"name":"HPOKI128_05975 alanyl-tRNA synthetase\tK01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]"
				},
				{
					"name":"HPOKI128_05470 valyl-tRNA synthetase\tK01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]"
				},
				{
					"name":"HPOKI128_04850 methionyl-tRNA synthetase\tK01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]"
				},
				{
					"name":"HPOKI128_06595 seryl-tRNA synthetase\tK01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]"
				},
				{
					"name":"HPOKI128_02940 aspartyl-tRNA synthetase\tK01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]"
				},
				{
					"name":"HPOKI128_04620 glycyl-tRNA synthetase\tK01878 glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14]"
				},
				{
					"name":"HPOKI128_04665 glycyl-tRNA synthetase subunit beta\tK01879 glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14]"
				},
				{
					"name":"HPOKI128_04240 cysteinyl-tRNA synthetase\tK01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]"
				},
				{
					"name":"HPOKI128_02365 glutamyl-tRNA synthetase\tK01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]"
				},
				{
					"name":"HPOKI128_01700 arginyl-tRNA synthetase\tK01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]"
				},
				{
					"name":"HPOKI128_04940 phenylalanyl-tRNA synthetase subunit alpha\tK01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]"
				},
				{
					"name":"HPOKI128_04945 phenylalanyl-tRNA synthetase subunit beta\tK01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]"
				},
				{
					"name":"HPOKI128_05690 histidyl-tRNA synthase\tK01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]"
				},
				{
					"name":"HPOKI128_03065 glutamyl-tRNA synthetase\tK09698 gltX; nondiscriminating glutamyl-tRNA synthetase [EC:6.1.1.24]"
				}
				]
			},
			{
				"name":"Trans-editing factors"
			}
			]
		},
		{
			"name":"tRNA modification factors",
			"children":[
			{
				"name":"Deaminases"
			},
			{
				"name":"Dihydorouridine synthases",
				"children":[
				{
					"name":"HPOKI128_03455 tRNA-dihydrouridine synthase\tK05540 dusB; tRNA-dihydrouridine synthase B [EC:1.-.-.-]"
				}
				]
			},
			{
				"name":"Methylthiotransferases",
				"children":[
				{
					"name":"HPOKI128_01470 (dimethylallyl)adenosine tRNA methylthiotransferase\tK06168 CDK5RAP1; tRNA-2-methylthio-N6-dimethylallyladenosine synthase [EC:2.8.4.3]"
				},
				{
					"name":"HPOKI128_01550 radical SAM protein\tK15865 CDKAL1; threonylcarbamoyladenosine tRNA methylthiotransferase [EC:2.8.4.5]"
				}
				]
			},
			{
				"name":"Methyltransferases",
				"children":[
				{
					"name":"HPOKI128_05015 tRNA methyltransferase\tK15256 cmoA; tRNA (cmo5U34)-methyltransferase [EC:2.1.1.-]"
				},
				{
					"name":"HPOKI128_04840 tRNA methyltransferase\tK15257 cmoB; tRNA (mo5U34)-methyltransferase [EC:2.1.1.-]"
				},
				{
					"name":"HPOKI128_03555 tRNA (guanine-N(7)-)-methyltransferase\tK03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33]"
				},
				{
					"name":"HPOKI128_05445 tRNA (guanine-N1)-methyltransferase\tK00554 trmD; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228]"
				},
				{
					"name":"HPOKI128_06740 tRNA modification GTPase TrmE\tK03650 mnmE; tRNA modification GTPase [EC:3.6.-.-]"
				}
				]
			},
			{
				"name":"Psudouridine synthases",
				"children":[
				{
					"name":"HPOKI128_05150 tRNA pseudouridine synthase A\tK06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]"
				},
				{
					"name":"HPOKI128_04435 tRNA pseudouridine synthase D\tK06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]"
				}
				]
			},
			{
				"name":"Thiolation factors",
				"children":[
				{
					"name":"HPOKI128_06015 ATP-binding protein\tK00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13]"
				},
				{
					"name":"HPOKI128_07225 thiouridylase\tK00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13]"
				},
				{
					"name":"HPOKI128_05650 PP-loop family protein\tK14058 ttcA; tRNA 2-thiocytidine biosynthesis protein TtcA"
				},
				{
					"name":"HPOKI128_01200 cysteine desulfarase\tK04487 iscS; cysteine desulfurase [EC:2.8.1.7]"
				}
				]
			},
			{
				"name":"KEOPS\/EKC complex"
			},
			{
				"name":"Other tRNA modification factors",
				"children":[
				{
					"name":"HPOKI128_01165 tRNA uridine 5-carboxymethylaminomethyl modification protein\tK03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme"
				},
				{
					"name":"HPOKI128_06945 tRNA delta(2)-isopentenylpyrophosphate transferase\tK00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]"
				},
				{
					"name":"HPOKI128_02025 S-adenosylmethionine tRNA ribosyltransferase\tK07568 queA; S-adenosylmethionine:tRNA ribosyltransferase-isomerase [EC:2.4.99.17]"
				},
				{
					"name":"HPOKI128_03050 7-cyano-7-deazaguanine synthase\tK06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20]"
				},
				{
					"name":"HPOKI128_04465 6-carboxy-5,6,7,8-tetrahydropterin synthase\tK01737 queD; 6-pyruvoyltetrahydropterin\/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50]"
				},
				{
					"name":"HPOKI128_04470 6-pyruvoyl tetrahydropterin synthase\tK10026 queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3]"
				},
				{
					"name":"HPOKI128_06955 7-cyano-7-deazaguanine reductase\tK09457 queF; 7-cyano-7-deazaguanine reductase [EC:1.7.1.13]"
				},
				{
					"name":"HPOKI128_00585 hypothetical protein\tK09765 queH; epoxyqueuosine reductase [EC:1.17.99.6]"
				},
				{
					"name":"HPOKI128_01530 queuine tRNA-ribosyltransferase\tK00773 tgt; queuine tRNA-ribosyltransferase [EC:2.4.2.29]"
				},
				{
					"name":"HPOKI128_03460 tRNA(Ile)-lysidine synthetase\tK04075 tilS; tRNA(Ile)-lysidine synthase [EC:6.3.4.19]"
				},
				{
					"name":"HPOKI128_02080 hypothetical protein\tK14742 tsaB; tRNA threonylcarbamoyladenosine biosynthesis protein TsaB"
				},
				{
					"name":"HPOKI128_00030 protein kinase\tK25706 tsaD; tRNA N6-adenosine threonylcarbamoyltransferase [EC:2.3.1.234]"
				},
				{
					"name":"HPOKI128_03405 P-loop hydrolase\tK06925 tsaE; tRNA threonylcarbamoyladenosine biosynthesis protein TsaE"
				},
				{
					"name":"HPOKI128_03595 MoeB\/ThiF family protein\tK22132 tcdA; tRNA threonylcarbamoyladenosine dehydratase"
				}
				]
			}
			]
		},
		{
			"name":"tRNA degradation factors",
			"children":[
			{
				"name":"HPOKI128_07675 ribonuclease R\tK12573 rnr; ribonuclease R [EC:3.1.13.1]"
			},
			{
				"name":"HPOKI128_05835 polynucleotide phosphorylase\tK00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]"
			}
			]
		}
		]
	}
	]
}