{
	"name":"hst03021",
	"children":[
	{
		"name":"Eukaryotic type",
		"children":[
		{
			"name":"RNA polymerase II system",
			"children":[
			{
				"name":"RNA polymerase II",
				"children":[
				{
					"name":"Core subunits",
					"children":[
					{
						"name":"105187653 DNA-directed RNA polymerase II subunit RPB1\tK03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]"
					},
					{
						"name":"105181898 DNA-directed RNA polymerase II subunit RPB2\tK03010 RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]"
					},
					{
						"name":"105185842 DNA-directed RNA polymerase II subunit RPB3\tK03011 RPB3; DNA-directed RNA polymerase II subunit RPB3"
					},
					{
						"name":"105182963 DNA-directed RNA polymerase II subunit RPB11\tK03008 RPB11; DNA-directed RNA polymerase II subunit RPB11"
					}
					]
				},
				{
					"name":"Pol II specific subunits",
					"children":[
					{
						"name":"105189103 DNA-directed RNA polymerase II subunit Rpb4 isoform X2\tK03012 RPB4; DNA-directed RNA polymerase II subunit RPB4"
					},
					{
						"name":"105186168 DNA-directed RNA polymerase II subunit RPB7\tK03015 RPB7; DNA-directed RNA polymerase II subunit RPB7"
					},
					{
						"name":"105192372 DNA-directed RNA polymerase II subunit RPB9\tK03017 RPB9; DNA-directed RNA polymerase II subunit RPB9"
					},
					{
						"name":"105182513 LOW QUALITY PROTEIN: uncharacterized protein LOC105182513\tK21987 POLR2M; DNA-directed RNA polymerase II subunit GRINL1A"
					}
					]
				},
				{
					"name":"Pol I, II, III common subunits",
					"children":[
					{
						"name":"105181521 DNA-directed RNA polymerases I, II, and III subunit RPABC1\tK03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1"
					},
					{
						"name":"105185542 DNA-directed RNA polymerases I, II, and III subunit RPABC2 isoform X2\tK03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2"
					},
					{
						"name":"105185973 DNA-directed RNA polymerases I, II, and III subunit RPABC2\tK03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2"
					},
					{
						"name":"105185593 DNA-directed RNA polymerases I, II, and III subunit RPABC3 isoform X3\tK03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3"
					},
					{
						"name":"105182879 DNA-directed RNA polymerases I, II, and III subunit RPABC4\tK03009 RPABC4; DNA-directed RNA polymerases I, II, and III subunit RPABC4"
					},
					{
						"name":"105189533 DNA-directed RNA polymerases I, II, and III subunit RPABC5\tK03007 RPABC5; DNA-directed RNA polymerases I, II, and III subunit RPABC5"
					}
					]
				},
				{
					"name":"Pol IV and V specific subunits"
				}
				]
			},
			{
				"name":"Basal transcription factors",
				"children":[
				{
					"name":"TFIIA",
					"children":[
					{
						"name":"105187257 transcription initiation factor IIA subunit 1 isoform X1\tK03122 TFIIA1; transcription initiation factor TFIIA large subunit"
					},
					{
						"name":"105182171 transcription initiation factor IIA subunit 2\tK03123 TFIIA2; transcription initiation factor TFIIA small subunit"
					}
					]
				},
				{
					"name":"TFIIB",
					"children":[
					{
						"name":"105188640 transcription initiation factor IIB isoform X1\tK03124 TFIIB; transcription initiation factor TFIIB"
					}
					]
				},
				{
					"name":"TFIID",
					"children":[
					{
						"name":"105183416 TATA-box-binding protein\tK03120 TBP; transcription initiation factor TFIID TATA-box-binding protein"
					},
					{
						"name":"105184205 TATA-box-binding protein\tK03120 TBP; transcription initiation factor TFIID TATA-box-binding protein"
					},
					{
						"name":"105191694 TATA box-binding protein-like protein 1\tK03120 TBP; transcription initiation factor TFIID TATA-box-binding protein"
					},
					{
						"name":"112588028 LOW QUALITY PROTEIN: TATA-box-binding protein-like\tK03120 TBP; transcription initiation factor TFIID TATA-box-binding protein"
					},
					{
						"name":"112589701 TATA-box-binding protein-like\tK03120 TBP; transcription initiation factor TFIID TATA-box-binding protein"
					},
					{
						"name":"105187652 transcription initiation factor TFIID subunit 1\tK03125 TAF1; transcription initiation factor TFIID subunit 1 [EC:2.3.1.48 2.7.11.1]"
					},
					{
						"name":"105183608 transcription initiation factor TFIID subunit 2\tK03128 TAF2; transcription initiation factor TFIID subunit 2"
					},
					{
						"name":"105186553 transcription initiation factor TFIID subunit 3 isoform X2\tK14650 TAF3; transcription initiation factor TFIID subunit 3"
					},
					{
						"name":"105188787 transcription initiation factor TFIID subunit 4 isoform X1\tK03129 TAF4; transcription initiation factor TFIID subunit 4"
					},
					{
						"name":"105187175 TAF5-like RNA polymerase II p300\/CBP-associated factor-associated factor 65 kDa subunit 5L isoform X1\tK03130 TAF5; transcription initiation factor TFIID subunit 5"
					},
					{
						"name":"105189876 transcription initiation factor TFIID subunit 5\tK03130 TAF5; transcription initiation factor TFIID subunit 5"
					},
					{
						"name":"105187816 transcription initiation factor TFIID subunit 6 isoform X1\tK03131 TAF6; transcription initiation factor TFIID subunit 6"
					},
					{
						"name":"105191514 uncharacterized protein LOC105191514\tK03131 TAF6; transcription initiation factor TFIID subunit 6"
					},
					{
						"name":"105187526 transcription initiation factor TFIID subunit 7\tK03132 TAF7; transcription initiation factor TFIID subunit 7"
					},
					{
						"name":"105186424 transcription initiation factor TFIID subunit 8\tK14649 TAF8; transcription initiation factor TFIID subunit 8"
					},
					{
						"name":"105192410 transcription initiation factor TFIID subunit 9 isoform X1\tK03133 TAF9B; transcription initiation factor TFIID subunit 9B"
					},
					{
						"name":"105181964 transcription initiation factor TFIID subunit 10\tK03134 TAF10; transcription initiation factor TFIID subunit 10"
					},
					{
						"name":"105184234 transcription initiation factor TFIID subunit 11\tK03135 TAF11; transcription initiation factor TFIID subunit 11"
					},
					{
						"name":"105185152 transcription initiation factor TFIID subunit 12\tK03126 TAF12; transcription initiation factor TFIID subunit 12"
					},
					{
						"name":"105189895 transcription initiation factor TFIID subunit 13 isoform X2\tK03127 TAF13; transcription initiation factor TFIID subunit 13"
					}
					]
				},
				{
					"name":"TFIIE",
					"children":[
					{
						"name":"105180658 general transcription factor IIE subunit 1\tK03136 TFIIE1; transcription initiation factor TFIIE subunit alpha"
					},
					{
						"name":"105182096 transcription initiation factor IIE subunit beta\tK03137 TFIIE2; transcription initiation factor TFIIE subunit beta"
					}
					]
				},
				{
					"name":"TFIIF",
					"children":[
					{
						"name":"105187629 general transcription factor IIF subunit 1\tK03138 TFIIF1; transcription initiation factor TFIIF subunit alpha"
					},
					{
						"name":"105185140 general transcription factor IIF subunit 2 isoform X1\tK03139 TFIIF2; transcription initiation factor TFIIF subunit beta [EC:5.6.2.-]"
					}
					]
				},
				{
					"name":"TFIIH",
					"children":[
					{
						"name":"105191402 general transcription factor IIH subunit 1\tK03141 TFIIH1; transcription initiation factor TFIIH subunit 1"
					},
					{
						"name":"105187846 general transcription factor IIH subunit 2\tK03142 TFIIH2; transcription initiation factor TFIIH subunit 2"
					},
					{
						"name":"105185170 general transcription factor IIH subunit 3\tK03143 TFIIH3; transcription initiation factor TFIIH subunit 3"
					},
					{
						"name":"105192296 general transcription factor IIH subunit 4\tK03144 TFIIH4; transcription initiation factor TFIIH subunit 4"
					},
					{
						"name":"105186413 general transcription and DNA repair factor IIH helicase subunit XPB\tK10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]"
					},
					{
						"name":"105181017 general transcription and DNA repair factor IIH helicase subunit XPD\tK10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]"
					},
					{
						"name":"105181385 general transcription factor IIH subunit 5\tK10845 TTDA; TFIIH basal transcription factor complex TTD-A subunit"
					},
					{
						"name":"105189821 cyclin-dependent kinase 7\tK02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]"
					},
					{
						"name":"105188248 CDK-activating kinase assembly factor MAT1\tK10842 MNAT1; CDK-activating kinase assembly factor MAT1"
					},
					{
						"name":"105187826 cyclin-H\tK06634 CCNH; cyclin H"
					}
					]
				}
				]
			},
			{
				"name":"Mediator complex",
				"children":[
				{
					"name":"Head",
					"children":[
					{
						"name":"105184707 mediator of RNA polymerase II transcription subunit 6\tK15128 MED6; mediator of RNA polymerase II transcription subunit 6"
					},
					{
						"name":"105189546 mediator of RNA polymerase II transcription subunit 8 isoform X2\tK15129 MED8; mediator of RNA polymerase II transcription subunit 8"
					},
					{
						"name":"105187948 mediator of RNA polymerase II transcription subunit 11\tK15131 MED11; mediator of RNA polymerase II transcription subunit 11"
					},
					{
						"name":"105192140 mediator of RNA polymerase II transcription subunit 17\tK15133 MED17; mediator of RNA polymerase II transcription subunit 17"
					},
					{
						"name":"105191846 mediator of RNA polymerase II transcription subunit 18\tK15135 MED18; mediator of RNA polymerase II transcription subunit 18"
					},
					{
						"name":"105192382 mediator of RNA polymerase II transcription subunit 19\tK15137 MED19; mediator of RNA polymerase II transcription subunit 19"
					},
					{
						"name":"105181231 mediator of RNA polymerase II transcription subunit 20 isoform X1\tK13528 MED20; mediator of RNA polymerase II transcription subunit 20"
					},
					{
						"name":"105184424 mediator of RNA polymerase II transcription subunit 22\tK15139 MED22; mediator of RNA polymerase II transcription subunit 22"
					},
					{
						"name":"105184013 mediator of RNA polymerase II transcription subunit 28 isoform X1\tK15141 MED28; mediator of RNA polymerase II transcription subunit 28"
					},
					{
						"name":"105190728 mediator of RNA polymerase II transcription subunit 29 isoform X2\tK15142 MED29; mediator of RNA polymerase II transcription subunit 29"
					},
					{
						"name":"105187740 mediator of RNA polymerase II transcription subunit 30 isoform X1\tK15143 MED30; mediator of RNA polymerase II transcription subunit 30"
					}
					]
				},
				{
					"name":"Middle",
					"children":[
					{
						"name":"105189310 mediator of RNA polymerase II transcription subunit 1\tK15144 MED1; mediator of RNA polymerase II transcription subunit 1"
					},
					{
						"name":"105182595 mediator of RNA polymerase II transcription subunit 4\tK15146 MED4; mediator of RNA polymerase II transcription subunit 4"
					},
					{
						"name":"105183445 mediator of RNA polymerase II transcription subunit 7\tK15148 MED7; mediator of RNA polymerase II transcription subunit 7"
					},
					{
						"name":"105180476 mediator of RNA polymerase II transcription subunit 9\tK15149 MED9; mediator of RNA polymerase II transcription subunit 9"
					},
					{
						"name":"105184377 mediator of RNA polymerase II transcription subunit 10\tK15151 MED10; mediator of RNA polymerase II transcription subunit 10"
					},
					{
						"name":"105189710 mediator of RNA polymerase II transcription subunit 21\tK15152 MED21; mediator of RNA polymerase II transcription subunit 21"
					},
					{
						"name":"105184081 mediator of RNA polymerase II transcription subunit 31-A\tK15153 MED31; mediator of RNA polymerase II transcription subunit 31"
					}
					]
				},
				{
					"name":"Tail",
					"children":[
					{
						"name":"105185527 mediator of RNA polymerase II transcription subunit 14 isoform X1\tK15156 MED14; mediator of RNA polymerase II transcription subunit 14"
					},
					{
						"name":"105191676 mediator of RNA polymerase II transcription subunit 15 isoform X1\tK15157 MED15; mediator of RNA polymerase II transcription subunit 15"
					},
					{
						"name":"105181461 mediator of RNA polymerase II transcription subunit 16 isoform X1\tK15159 MED16; mediator of RNA polymerase II transcription subunit 16"
					}
					]
				},
				{
					"name":"CDK-module",
					"children":[
					{
						"name":"105191089 cyclin-dependent kinase 8\tK02208 CDK8_11; cyclin-dependent kinase 8\/11 [EC:2.7.11.22 2.7.11.23]"
					},
					{
						"name":"105192297 cyclin-C\tK15161 CCNC; cyclin-C"
					},
					{
						"name":"105190745 mediator of RNA polymerase II transcription subunit 12\tK15162 MED12; mediator of RNA polymerase II transcription subunit 12"
					},
					{
						"name":"105181553 mediator of RNA polymerase II transcription subunit 13 isoform X1\tK15164 MED13; mediator of RNA polymerase II transcription subunit 13"
					}
					]
				},
				{
					"name":"Other mediators",
					"children":[
					{
						"name":"105182026 mediator of RNA polymerase II transcription subunit 23\tK15166 MED23; mediator of RNA polymerase II transcription subunit 23"
					},
					{
						"name":"105184160 mediator of RNA polymerase II transcription subunit 24 isoform X1\tK15167 MED24; mediator of RNA polymerase II transcription subunit 24"
					},
					{
						"name":"105182254 mediator of RNA polymerase II transcription subunit 25 isoform X1\tK15168 MED25; mediator of RNA polymerase II transcription subunit 25"
					},
					{
						"name":"105183398 mediator of RNA polymerase II transcription subunit 25\tK15168 MED25; mediator of RNA polymerase II transcription subunit 25"
					},
					{
						"name":"105188382 mediator of RNA polymerase II transcription subunit 26 isoform X1\tK15169 MED26; mediator of RNA polymerase II transcription subunit 26"
					},
					{
						"name":"105189263 mediator of RNA polymerase II transcription subunit 27\tK15170 MED27; mediator of RNA polymerase II transcription subunit 27"
					}
					]
				}
				]
			},
			{
				"name":"Coactivators",
				"children":[
				{
					"name":"SAGA\/TFTC\/STAGA complex",
					"children":[
					{
						"name":"105189672 histone acetyltransferase KAT2A\tK06062 PCAF; histone acetyltransferase [EC:2.3.1.48]"
					},
					{
						"name":"105189674 histone acetyltransferase KAT2A\tK06062 PCAF; histone acetyltransferase [EC:2.3.1.48]"
					},
					{
						"name":"105184157 transformation\/transcription domain-associated protein\tK08874 TRRAP; transformation\/transcription domain-associated protein"
					},
					{
						"name":"105184872 transcription initiation protein SPT3 homolog\tK11313 SUPT3H; transcription initiation protein SPT3"
					},
					{
						"name":"105191685 transcriptional adapter 2B\tK15127 TADA2B; transcriptional adapter 2-beta"
					},
					{
						"name":"105186886 transcriptional adapter 3-A\tK11315 TADA3; transcriptional adapter 3"
					},
					{
						"name":"105180552 transcriptional adapter 1\tK11317 TADA1; transcriptional adapter 1"
					},
					{
						"name":"105183608 transcription initiation factor TFIID subunit 2\tK03128 TAF2; transcription initiation factor TFIID subunit 2"
					},
					{
						"name":"105188787 transcription initiation factor TFIID subunit 4 isoform X1\tK03129 TAF4; transcription initiation factor TFIID subunit 4"
					},
					{
						"name":"105187175 TAF5-like RNA polymerase II p300\/CBP-associated factor-associated factor 65 kDa subunit 5L isoform X1\tK03130 TAF5; transcription initiation factor TFIID subunit 5"
					},
					{
						"name":"105189876 transcription initiation factor TFIID subunit 5\tK03130 TAF5; transcription initiation factor TFIID subunit 5"
					},
					{
						"name":"105187816 transcription initiation factor TFIID subunit 6 isoform X1\tK03131 TAF6; transcription initiation factor TFIID subunit 6"
					},
					{
						"name":"105191514 uncharacterized protein LOC105191514\tK03131 TAF6; transcription initiation factor TFIID subunit 6"
					},
					{
						"name":"105187526 transcription initiation factor TFIID subunit 7\tK03132 TAF7; transcription initiation factor TFIID subunit 7"
					},
					{
						"name":"105192410 transcription initiation factor TFIID subunit 9 isoform X1\tK03133 TAF9B; transcription initiation factor TFIID subunit 9B"
					},
					{
						"name":"105181964 transcription initiation factor TFIID subunit 10\tK03134 TAF10; transcription initiation factor TFIID subunit 10"
					},
					{
						"name":"105185152 transcription initiation factor TFIID subunit 12\tK03126 TAF12; transcription initiation factor TFIID subunit 12"
					},
					{
						"name":"105191111 ataxin-7-like protein 3\tK11363 ATXN7L; SAGA-associated factor 11"
					},
					{
						"name":"105190551 SAGA-associated factor 29\tK11364 SGF29; SAGA-associated factor 29"
					},
					{
						"name":"105182228 uncharacterized protein LOC105182228 isoform X1\tK11316 SUPT7L; STAGA complex 65 subunit gamma"
					},
					{
						"name":"105181142 ataxin-7-like protein 1 isoform X1\tK11318 ATXN7; ataxin-7"
					},
					{
						"name":"105181023 chromodomain-helicase-DNA-binding protein 1 isoform X1\tK11367 CHD1; chromodomain-helicase-DNA-binding protein 1 [EC:5.6.2.-]"
					},
					{
						"name":"105186890 transcription and mRNA export factor ENY2\tK11368 ENY2; enhancer of yellow 2 transcription factor"
					},
					{
						"name":"105182860 ubiquitin carboxyl-terminal hydrolase 22\tK11366 USP22_27_51; ubiquitin carboxyl-terminal hydrolase 22\/27\/51 [EC:3.4.19.12]"
					},
					{
						"name":"105183557 splicing factor 3B subunit 3\tK12830 SF3B3; splicing factor 3B subunit 3"
					}
					]
				},
				{
					"name":"BAF\/PBAF complex",
					"children":[
					{
						"name":"105181112 ATP-dependent helicase brm\tK11647 SMARCA2_4; SWI\/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2\/4 [EC:5.6.2.-]"
					},
					{
						"name":"105183156 SWI\/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1\tK11648 SMARCB1; SWI\/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1"
					},
					{
						"name":"105184838 SWI\/SNF complex subunit SMARCC2\tK11649 SMARCC; SWI\/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C"
					},
					{
						"name":"105183399 brahma-associated protein of 60 kDa isoform X1\tK11650 SMARCD; SWI\/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D"
					},
					{
						"name":"105189764 transcription factor SPT20 homolog isoform X1\tK11651 SMARCE1; SWI\/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1"
					},
					{
						"name":"105183366 actin-5C\tK05692 ACTB_G1; actin beta\/gamma 1"
					},
					{
						"name":"105188751 actin-5, muscle-specific\tK05692 ACTB_G1; actin beta\/gamma 1"
					},
					{
						"name":"105188753 actin, muscle\tK05692 ACTB_G1; actin beta\/gamma 1"
					},
					{
						"name":"105188754 actin-5, muscle-specific\tK05692 ACTB_G1; actin beta\/gamma 1"
					},
					{
						"name":"105189671 actin-5C\tK05692 ACTB_G1; actin beta\/gamma 1"
					},
					{
						"name":"105185182 actin-like protein 6B\tK11652 ACTL6B; actin-like protein 6B"
					},
					{
						"name":"105185541 actin-like protein 6B\tK11652 ACTL6B; actin-like protein 6B"
					},
					{
						"name":"105181059 trithorax group protein osa isoform X1\tK11653 ARID1; AT-rich interactive domain-containing protein 1"
					},
					{
						"name":"105182077 AT-rich interactive domain-containing protein 2 isoform X1\tK11765 ARID2; AT-rich interactive domain-containing protein 2"
					},
					{
						"name":"105182221 protein polybromo-1 isoform X1\tK11757 PBRM1; protein polybromo-1"
					}
					]
				},
				{
					"name":"SWI\/SNF complex",
					"children":[
					{
						"name":"105183156 SWI\/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1\tK11648 SMARCB1; SWI\/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1"
					}
					]
				},
				{
					"name":"RSC complex"
				},
				{
					"name":"Others",
					"children":[
					{
						"name":"105180735 activated RNA polymerase II transcriptional coactivator p15 isoform X1\tK25815 SUB1; activated RNA polymerase II transcriptional coactivator p15"
					},
					{
						"name":"105187684 cell division cycle and apoptosis regulator protein 1 isoform X1\tK25827 CCAR1; cell division cycle and apoptosis regulator protein 1"
					}
					]
				}
				]
			},
			{
				"name":"Other transcription-related factors",
				"children":[
				{
					"name":"Transcription elongation factors",
					"children":[
					{
						"name":"105191047 transcription elongation factor S-II isoform X1\tK03145 TFIIS; transcription elongation factor S-II"
					},
					{
						"name":"105192571 transcription elongation factor SPT4-A\tK15171 SUPT4H1; transcription elongation factor SPT4"
					},
					{
						"name":"105186419 transcription elongation factor SPT5\tK15172 SUPT5H; transcription elongation factor SPT5"
					},
					{
						"name":"105186731 transcription elongation factor SPT6 isoform X2\tK11292 SUPT6H; transcription elongation factor SPT6"
					}
					]
				},
				{
					"name":"Transcription termination factor",
					"children":[
					{
						"name":"105188497 transcription termination factor 2\tK15173 TTF2; transcription termination factor 2 [EC:5.6.2.-]"
					},
					{
						"name":"105188277 uncharacterized protein LOC105188277 isoform X1\tK14400 PCF11; pre-mRNA cleavage complex 2 protein Pcf11"
					},
					{
						"name":"105191528 cleavage and polyadenylation specificity factor subunit 1\tK14401 CPSF1; cleavage and polyadenylation specificity factor subunit 1"
					},
					{
						"name":"105187255 cleavage and polyadenylation specificity factor 73\tK14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]"
					},
					{
						"name":"105186593 cleavage and polyadenylation specificity factor subunit 4\tK14404 CPSF4; cleavage and polyadenylation specificity factor subunit 4"
					},
					{
						"name":"105181250 serine\/threonine-protein phosphatase alpha-2 isoform\tK06269 PPP1C; serine\/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"105190124 serine\/threonine-protein phosphatase PP1-beta catalytic subunit isoform X1\tK06269 PPP1C; serine\/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"105189956 symplekin\tK06100 SYMPK; symplekin"
					},
					{
						"name":"105190776 RNA polymerase II subunit A C-terminal domain phosphatase SSU72\tK15544 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 [EC:3.1.3.16]"
					},
					{
						"name":"105184218 5'-3' exoribonuclease 2 homolog\tK12619 XRN2; 5'-3' exoribonuclease 2 [EC:3.1.13.-]"
					},
					{
						"name":"105188691 regulation of nuclear pre-mRNA domain-containing protein 1B isoform X1\tK15559 RTT103; regulator of Ty1 transposition protein 103"
					},
					{
						"name":"105186771 hrp65 protein isoform X1\tK13219 SFPQ; splicing factor, proline- and glutamine-rich"
					},
					{
						"name":"105187990 splicing factor, arginine\/serine-rich 15\tK13191 RBM16; RNA-binding protein 16"
					},
					{
						"name":"105186779 putative peptidyl-prolyl cis-trans isomerase dodo isoform X1\tK09578 PIN1; peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 [EC:5.2.1.8]"
					}
					]
				},
				{
					"name":"PAF1 complex",
					"children":[
					{
						"name":"105186984 RNA polymerase II-associated factor 1 homolog\tK15174 PAF1; RNA polymerase II-associated factor 1"
					},
					{
						"name":"105187168 RNA polymerase II-associated factor 1 homolog\tK15174 PAF1; RNA polymerase II-associated factor 1"
					},
					{
						"name":"105189082 parafibromin\tK15175 CDC73; parafibromin"
					},
					{
						"name":"105188293 RNA polymerase-associated protein CTR9 homolog\tK15176 CTR9; RNA polymerase-associated protein CTR9"
					},
					{
						"name":"105187444 another transcription unit protein isoform X3\tK15177 LEO1; RNA polymerase-associated protein LEO1"
					},
					{
						"name":"105184033 RNA polymerase-associated protein RTF1 homolog isoform X1\tK15178 RTF1; RNA polymerase-associated protein RTF1"
					}
					]
				},
				{
					"name":"NELF complex",
					"children":[
					{
						"name":"105191975 negative elongation factor A\tK15179 WHSC2; negative elongation factor A"
					},
					{
						"name":"105192006 negative elongation factor B\tK15180 COBRA1; negative elongation factor B"
					},
					{
						"name":"105182086 negative elongation factor D\tK15181 TH1L; negative elongation factor C\/D"
					},
					{
						"name":"105185762 negative elongation factor E isoform X1\tK15182 RDBP; negative elongation factor E"
					}
					]
				},
				{
					"name":"Super elongation complex (SEC)",
					"children":[
					{
						"name":"105181242 RNA polymerase II elongation factor Ell\tK15183 ELL; RNA polymerase II elongation factor ELL"
					},
					{
						"name":"105190763 ell-associated factor Eaf\tK15186 EAF; ELL-associated factor"
					},
					{
						"name":"105188800 protein AF-9\tK15187 MLLT1_3; YEATS domain-containing protein 1\/3"
					},
					{
						"name":"105189408 cyclin-T isoform X1\tK15188 CCNT; cyclin T"
					},
					{
						"name":"105185420 cyclin-dependent kinase 9 isoform X1\tK02211 CDK9; cyclin-dependent kinase 9 [EC:2.7.11.22 2.7.11.23]"
					}
					]
				},
				{
					"name":"Little elongation complex (LEC)",
					"children":[
					{
						"name":"105181242 RNA polymerase II elongation factor Ell\tK15183 ELL; RNA polymerase II elongation factor ELL"
					},
					{
						"name":"105183237 uncharacterized protein LOC105183237 isoform X1\tK26144 ICE2; little elongation complex subunit 2"
					}
					]
				},
				{
					"name":"Brd4\/P-TEFb complex",
					"children":[
					{
						"name":"105190044 homeotic protein female sterile isoform X1\tK11722 BRD4; bromodomain-containing protein 4"
					},
					{
						"name":"105189408 cyclin-T isoform X1\tK15188 CCNT; cyclin T"
					},
					{
						"name":"105185420 cyclin-dependent kinase 9 isoform X1\tK02211 CDK9; cyclin-dependent kinase 9 [EC:2.7.11.22 2.7.11.23]"
					}
					]
				},
				{
					"name":"BUR kinase complex"
				},
				{
					"name":"CTDK-I complex"
				},
				{
					"name":"7SK RNP complex",
					"children":[
					{
						"name":"105183658 protein HEXIM\tK15189 HEXIM1_2; protein HEXIM1\/2"
					},
					{
						"name":"105187226 7SK snRNA methylphosphate capping enzyme isoform X1\tK15190 MEPCE; 7SK snRNA methylphosphate capping enzyme [EC:2.1.1.-]"
					},
					{
						"name":"105191972 la-related protein 7\tK15191 LARP7; La-related protein 7"
					},
					{
						"name":"105189408 cyclin-T isoform X1\tK15188 CCNT; cyclin T"
					},
					{
						"name":"105185420 cyclin-dependent kinase 9 isoform X1\tK02211 CDK9; cyclin-dependent kinase 9 [EC:2.7.11.22 2.7.11.23]"
					}
					]
				},
				{
					"name":"DBIRD complex"
				},
				{
					"name":"Others",
					"children":[
					{
						"name":"105183129 TATA-binding protein-associated factor 172\tK15192 BTAF1; TATA-binding protein-associated factor [EC:5.6.2.-]"
					},
					{
						"name":"112589145 TATA-binding protein-associated factor 172-like\tK15192 BTAF1; TATA-binding protein-associated factor [EC:5.6.2.-]"
					},
					{
						"name":"105191557 protein Dr1 isoform X2\tK21751 DR1; down-regulator of transcription 1"
					},
					{
						"name":"105186638 dr1-associated corepressor\tK21752 DRAP1; Dr1-associated corepressor"
					},
					{
						"name":"105185806 protein SPT2 homolog\tK15193 SPTY2D1; protein SPT2"
					},
					{
						"name":"105192318 RNA polymerase II subunit A C-terminal domain phosphatase\tK15732 CTDP1; RNA polymerase II subunit A C-terminal domain phosphatase [EC:3.1.3.16]"
					},
					{
						"name":"105180816 carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 isoform X1\tK15731 CTDSP; carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase [EC:3.1.3.16]"
					},
					{
						"name":"105184735 IWS1-like protein isoform X1\tK17498 SPN1; transcription factor SPN1"
					},
					{
						"name":"105190991 uncharacterized protein LOC105190991\tK17494 CSRNP; cysteine\/serine-rich nuclear protein"
					},
					{
						"name":"105181857 RNA polymerase II-associated protein 1\tK20826 RPAP1; RNA polymerase II-associated protein 1"
					},
					{
						"name":"105190914 RNA polymerase II subunit B1 CTD phosphatase Rpap2 isoform X1\tK20827 RPAP2; RNA polymerase II-associated protein 2 [EC:3.1.3.16]"
					},
					{
						"name":"105182919 RNA polymerase II-associated protein 3 isoform X1\tK23002 RPAP3; RNA polymerase II-associated protein 3"
					},
					{
						"name":"105182866 cyclin-K\tK23326 CCNK; cyclin K"
					},
					{
						"name":"105182199 GPN-loop GTPase 3\tK24104 GPN; GPN-loop GTPase"
					},
					{
						"name":"105184309 GPN-loop GTPase 1\tK24104 GPN; GPN-loop GTPase"
					},
					{
						"name":"105187901 GPN-loop GTPase 2 isoform X1\tK24104 GPN; GPN-loop GTPase"
					},
					{
						"name":"105189057 probable RNA polymerase II nuclear localization protein SLC7A6OS\tK28237 SLC7A6OS; RNA polymerase II nuclear localization protein"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"RNA polymerase III system",
			"children":[
			{
				"name":"RNA polymerase III",
				"children":[
				{
					"name":"Core subunits",
					"children":[
					{
						"name":"105189020 DNA-directed RNA polymerase III subunit RPC1\tK03018 RPC1; DNA-directed RNA polymerase III subunit RPC1 [EC:2.7.7.6]"
					},
					{
						"name":"105183243 DNA-directed RNA polymerases I and III subunit RPAC1\tK03027 RPAC1; DNA-directed RNA polymerases I and III subunit RPAC1"
					},
					{
						"name":"105189738 probable DNA-directed RNA polymerases I and III subunit RPAC2\tK03020 RPAC2; DNA-directed RNA polymerases I and III subunit RPAC2"
					}
					]
				},
				{
					"name":"Pol III specific subunits",
					"children":[
					{
						"name":"105185309 DNA-directed RNA polymerase III subunit RPC3\tK03023 RPC3; DNA-directed RNA polymerase III subunit RPC3"
					},
					{
						"name":"105190772 DNA-directed RNA polymerase III subunit RPC4 isoform X1\tK03026 RPC4; DNA-directed RNA polymerase III subunit RPC4"
					},
					{
						"name":"112590021 DNA-directed RNA polymerase III subunit RPC4-like isoform X1\tK03026 RPC4; DNA-directed RNA polymerase III subunit RPC4"
					},
					{
						"name":"105185468 DNA-directed RNA polymerase III subunit RPC5\tK14721 RPC5; DNA-directed RNA polymerase III subunit RPC5"
					},
					{
						"name":"105182459 probable DNA-directed RNA polymerase III subunit RPC6\tK03025 RPC6; DNA-directed RNA polymerase III subunit RPC6"
					},
					{
						"name":"105190231 DNA-directed RNA polymerase III subunit RPC7-like\tK03024 RPC7; DNA-directed RNA polymerase III subunit RPC7"
					},
					{
						"name":"105185866 DNA-directed RNA polymerase III subunit RPC8\tK03022 RPC8; DNA-directed RNA polymerase III subunit RPC8"
					},
					{
						"name":"105188446 DNA-directed RNA polymerase III subunit RPC9\tK25304 RPC9; DNA-directed RNA polymerase III subunit RPC9"
					},
					{
						"name":"112588535 DNA-directed RNA polymerase III subunit RPC10\tK03019 RPC11; DNA-directed RNA polymerase III subunit RPC11"
					}
					]
				},
				{
					"name":"Pol I, II, III common subunits",
					"children":[
					{
						"name":"105181521 DNA-directed RNA polymerases I, II, and III subunit RPABC1\tK03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1"
					},
					{
						"name":"105185542 DNA-directed RNA polymerases I, II, and III subunit RPABC2 isoform X2\tK03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2"
					},
					{
						"name":"105185973 DNA-directed RNA polymerases I, II, and III subunit RPABC2\tK03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2"
					},
					{
						"name":"105185593 DNA-directed RNA polymerases I, II, and III subunit RPABC3 isoform X3\tK03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3"
					},
					{
						"name":"105182879 DNA-directed RNA polymerases I, II, and III subunit RPABC4\tK03009 RPABC4; DNA-directed RNA polymerases I, II, and III subunit RPABC4"
					},
					{
						"name":"105189533 DNA-directed RNA polymerases I, II, and III subunit RPABC5\tK03007 RPABC5; DNA-directed RNA polymerases I, II, and III subunit RPABC5"
					}
					]
				}
				]
			},
			{
				"name":"Basal transcription factors",
				"children":[
				{
					"name":"TFIIIA",
					"children":[
					{
						"name":"105183333 zinc finger protein 708\tK09191 GTF3A; general transcription factor IIIA"
					},
					{
						"name":"105190748 zinc finger protein 501-like\tK09191 GTF3A; general transcription factor IIIA"
					}
					]
				},
				{
					"name":"TFIIIB",
					"children":[
					{
						"name":"105183416 TATA-box-binding protein\tK03120 TBP; transcription initiation factor TFIID TATA-box-binding protein"
					},
					{
						"name":"105184205 TATA-box-binding protein\tK03120 TBP; transcription initiation factor TFIID TATA-box-binding protein"
					},
					{
						"name":"105191694 TATA box-binding protein-like protein 1\tK03120 TBP; transcription initiation factor TFIID TATA-box-binding protein"
					},
					{
						"name":"112588028 LOW QUALITY PROTEIN: TATA-box-binding protein-like\tK03120 TBP; transcription initiation factor TFIID TATA-box-binding protein"
					},
					{
						"name":"112589701 TATA-box-binding protein-like\tK03120 TBP; transcription initiation factor TFIID TATA-box-binding protein"
					},
					{
						"name":"105190966 transcription factor IIIB 90 kDa subunit\tK15196 BRF1; transcription factor IIIB 90 kDa subunit"
					},
					{
						"name":"105192623 transcription factor TFIIIB component B'' homolog isoform X1\tK15198 BDP1; transcription factor TFIIIB component B''"
					}
					]
				},
				{
					"name":"TFIIIC",
					"children":[
					{
						"name":"105185757 general transcription factor 3C polypeptide 1\tK15199 GTF3C1; general transcription factor 3C polypeptide 1"
					},
					{
						"name":"105187155 general transcription factor 3C polypeptide 2 isoform X1\tK15200 GTF3C2; general transcription factor 3C polypeptide 2"
					},
					{
						"name":"105184453 general transcription factor 3C polypeptide 3 isoform X1\tK15201 GTP3C3; general transcription factor 3C polypeptide 3 (transcription factor C subunit 4)"
					},
					{
						"name":"105184042 uncharacterized protein LOC105184042\tK11310 GTF3C4; general transcription factor 3C polypeptide 4 [EC:2.3.1.48]"
					},
					{
						"name":"105182958 general transcription factor 3C polypeptide 5 isoform X1\tK15202 GTF3C5; general transcription factor 3C polypeptide 5 (transcription factor C subunit 1)"
					},
					{
						"name":"105184392 general transcription factor 3C polypeptide 6\tK15203 GTF3C6; general transcription factor 3C polypeptide 6"
					}
					]
				},
				{
					"name":"TFIIIC, fungi type",
					"children":[
					{
						"name":"105182958 general transcription factor 3C polypeptide 5 isoform X1\tK15202 GTF3C5; general transcription factor 3C polypeptide 5 (transcription factor C subunit 1)"
					},
					{
						"name":"105184453 general transcription factor 3C polypeptide 3 isoform X1\tK15201 GTP3C3; general transcription factor 3C polypeptide 3 (transcription factor C subunit 4)"
					}
					]
				}
				]
			},
			{
				"name":"Other transcription-related factors",
				"children":[
				{
					"name":"snRNA-activating protein complex (SNAPc)",
					"children":[
					{
						"name":"105186111 uncharacterized protein LOC105186111\tK15208 SNAPC1; snRNA-activating protein complex subunit 1"
					},
					{
						"name":"105191554 snRNA-activating protein complex subunit 3 isoform X1\tK15210 SNAPC3; snRNA-activating protein complex subunit 3"
					}
					]
				},
				{
					"name":"Octamer transcription factors",
					"children":[
					{
						"name":"105185228 POU domain protein 2 isoform X1\tK09364 POU2F; POU domain transcription factor, class 2"
					}
					]
				},
				{
					"name":"Others",
					"children":[
					{
						"name":"105183148 zinc finger protein 143-like\tK20828 ZNF143_76; zinc finger protein 143\/76"
					},
					{
						"name":"105183210 repressor of RNA polymerase III transcription MAF1 homolog\tK25817 MAF1; repressor of RNA polymerase III transcription MAF1"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"RNA polymerase I system",
			"children":[
			{
				"name":"RNA polymerase I",
				"children":[
				{
					"name":"Core subunits",
					"children":[
					{
						"name":"105185827 DNA-directed RNA polymerase I subunit RPA1 isoform X1\tK02999 RPA1; DNA-directed RNA polymerase I subunit RPA1 [EC:2.7.7.6]"
					},
					{
						"name":"105189935 DNA-directed RNA polymerase I subunit RPA2\tK03002 RPA2; DNA-directed RNA polymerase I subunit RPA2 [EC:2.7.7.6]"
					},
					{
						"name":"105183243 DNA-directed RNA polymerases I and III subunit RPAC1\tK03027 RPAC1; DNA-directed RNA polymerases I and III subunit RPAC1"
					},
					{
						"name":"105189738 probable DNA-directed RNA polymerases I and III subunit RPAC2\tK03020 RPAC2; DNA-directed RNA polymerases I and III subunit RPAC2"
					}
					]
				},
				{
					"name":"Pol I specific subunits",
					"children":[
					{
						"name":"105183234 uncharacterized protein LOC105183234\tK03005 RPA49; DNA-directed RNA polymerase I subunit RPA49"
					},
					{
						"name":"105191945 probable DNA-directed RNA polymerase I subunit RPA43\tK03004 RPA43; DNA-directed RNA polymerase I subunit RPA43"
					},
					{
						"name":"105190271 DNA-directed RNA polymerase I subunit RPA12\tK03000 RPA12; DNA-directed RNA polymerase I subunit RPA12"
					}
					]
				},
				{
					"name":"Pol I, II, III common subunits",
					"children":[
					{
						"name":"105181521 DNA-directed RNA polymerases I, II, and III subunit RPABC1\tK03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1"
					},
					{
						"name":"105185542 DNA-directed RNA polymerases I, II, and III subunit RPABC2 isoform X2\tK03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2"
					},
					{
						"name":"105185973 DNA-directed RNA polymerases I, II, and III subunit RPABC2\tK03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2"
					},
					{
						"name":"105185593 DNA-directed RNA polymerases I, II, and III subunit RPABC3 isoform X3\tK03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3"
					},
					{
						"name":"105182879 DNA-directed RNA polymerases I, II, and III subunit RPABC4\tK03009 RPABC4; DNA-directed RNA polymerases I, II, and III subunit RPABC4"
					},
					{
						"name":"105189533 DNA-directed RNA polymerases I, II, and III subunit RPABC5\tK03007 RPABC5; DNA-directed RNA polymerases I, II, and III subunit RPABC5"
					}
					]
				}
				]
			},
			{
				"name":"Basal transcription factors",
				"children":[
				{
					"name":"SL1\/TIF-1B",
					"children":[
					{
						"name":"105183416 TATA-box-binding protein\tK03120 TBP; transcription initiation factor TFIID TATA-box-binding protein"
					},
					{
						"name":"105184205 TATA-box-binding protein\tK03120 TBP; transcription initiation factor TFIID TATA-box-binding protein"
					},
					{
						"name":"105191694 TATA box-binding protein-like protein 1\tK03120 TBP; transcription initiation factor TFIID TATA-box-binding protein"
					},
					{
						"name":"112588028 LOW QUALITY PROTEIN: TATA-box-binding protein-like\tK03120 TBP; transcription initiation factor TFIID TATA-box-binding protein"
					},
					{
						"name":"112589701 TATA-box-binding protein-like\tK03120 TBP; transcription initiation factor TFIID TATA-box-binding protein"
					},
					{
						"name":"105180877 TATA box-binding protein-associated factor RNA polymerase I subunit B\tK15213 TAF1B; TATA box-binding protein-associated factor RNA polymerase I subunit B"
					}
					]
				}
				]
			},
			{
				"name":"Other transcription-related factors",
				"children":[
				{
					"name":"UBF"
				},
				{
					"name":"Transcription initiation factors",
					"children":[
					{
						"name":"105188341 RNA polymerase I-specific transcription initiation factor RRN3\tK15216 RRN3; RNA polymerase I-specific transcription initiation factor RRN3"
					},
					{
						"name":"105183681 upstream activation factor subunit spp27\tK15223 UAF30; upstream activation factor subunit UAF30"
					}
					]
				},
				{
					"name":"Transcription elongation factors",
					"children":[
					{
						"name":"105192571 transcription elongation factor SPT4-A\tK15171 SUPT4H1; transcription elongation factor SPT4"
					},
					{
						"name":"105186419 transcription elongation factor SPT5\tK15172 SUPT5H; transcription elongation factor SPT5"
					}
					]
				},
				{
					"name":"NoRC (nucleolar remodeling complex)",
					"children":[
					{
						"name":"105192586 chromatin-remodeling complex ATPase chain Iswi\tK11654 SMARCA5; SWI\/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 [EC:5.6.2.-]"
					}
					]
				},
				{
					"name":"CTDK-I complex"
				},
				{
					"name":"Transcription termination factors"
				},
				{
					"name":"Others",
					"children":[
					{
						"name":"105180780 nucleolar and coiled-body phosphoprotein 1 isoform X1\tK25818 NOLC1; nucleolar and coiled-body phosphoprotein 1"
					}
					]
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic type",
		"children":[
		{
			"name":"Bacterial type",
			"children":[
			{
				"name":"RNA polymerase",
				"children":[
				{
					"name":"Core subunits"
				},
				{
					"name":"Sigma factors"
				}
				]
			},
			{
				"name":"Other transcription-related factors",
				"children":[
				{
					"name":"RNA polymerase-associated proteins"
				},
				{
					"name":"Transcription elongation factors"
				},
				{
					"name":"Transcription termination factor"
				}
				]
			}
			]
		},
		{
			"name":"Archaeal type",
			"children":[
			{
				"name":"RNA polymerase",
				"children":[
				{
					"name":"Core subunits"
				}
				]
			},
			{
				"name":"Basal transcription factors",
				"children":[
				{
					"name":"TFB",
					"children":[
					{
						"name":"105188640 transcription initiation factor IIB isoform X1\tK03124 TFIIB; transcription initiation factor TFIIB"
					}
					]
				},
				{
					"name":"TFE",
					"children":[
					{
						"name":"105180658 general transcription factor IIE subunit 1\tK03136 TFIIE1; transcription initiation factor TFIIE subunit alpha"
					}
					]
				},
				{
					"name":"TFS"
				}
				]
			}
			]
		}
		]
	}
	]
}