{ "name":"hsyr03400", "children":[ { "name":"Eukaryotic type", "children":[ { "name":"SSBR (single strand breaks repair)", "children":[ { "name":"Direct repair", "children":[ { "name":"120169350 DNA oxidative demethylase ALKBH2-like\tK10859 ALKBH2; DNA oxidative demethylase [EC:1.14.11.33]" }, { "name":"120174262 DNA oxidative demethylase ALKBH2-like\tK10859 ALKBH2; DNA oxidative demethylase [EC:1.14.11.33]" }, { "name":"120174885 DNA oxidative demethylase ALKBH2-like\tK10859 ALKBH2; DNA oxidative demethylase [EC:1.14.11.33]" }, { "name":"120215819 DNA oxidative demethylase ALKBH2-like\tK10859 ALKBH2; DNA oxidative demethylase [EC:1.14.11.33]" }, { "name":"120215957 DExH-box ATP-dependent RNA helicase DExH14 isoform X1\tK18663 ASCC3; activating signal cointegrator complex subunit 3 [EC:5.6.2.4]" }, { "name":"120158718 LOW QUALITY PROTEIN: deoxyribodipyrimidine photo-lyase-like\tK01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]" } ] }, { "name":"BER (base exicision repair)", "children":[ { "name":"DNA glycosylases", "children":[ { "name":"120187493 uracil-DNA glycosylase, mitochondrial\tK03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]" }, { "name":"120203817 uracil-DNA glycosylase, mitochondrial-like\tK03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]" }, { "name":"120169503 DNA-3-methyladenine glycosylase\tK03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]" }, { "name":"120114027 adenine DNA glycosylase-like\tK03575 mutY; A\/G-specific adenine glycosylase [EC:3.2.2.31]" }, { "name":"120121087 adenine DNA glycosylase-like\tK03575 mutY; A\/G-specific adenine glycosylase [EC:3.2.2.31]" }, { "name":"120209378 LOW QUALITY PROTEIN: methyl-CpG-binding domain protein 4-like protein\tK10801 MBD4; methyl-CpG-binding domain protein 4 [EC:3.2.2.-]" }, { "name":"120139664 endonuclease III homolog 1, chloroplastic\tK10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]" } ] }, { "name":"AP endonucleases", "children":[ { "name":"120166782 DNA-(apurinic or apyrimidinic site) endonuclease 2-like isoform X1\tK10772 APEX2; AP endonuclease 2 [EC:3.1.11.2]" } ] }, { "name":"Long Patch-BER factors", "children":[ { "name":"DNA polymerase delta complex", "children":[ { "name":"120123266 LOW QUALITY PROTEIN: DNA polymerase delta catalytic subunit-like\tK02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]" }, { "name":"120169661 DNA polymerase delta small subunit-like\tK02328 POLD2; DNA polymerase delta subunit 2" }, { "name":"120177759 DNA polymerase delta small subunit-like\tK02328 POLD2; DNA polymerase delta subunit 2" }, { "name":"120143972 uncharacterized protein LOC120143972\tK03504 POLD3; DNA polymerase delta subunit 3" }, { "name":"120219437 uncharacterized protein LOC120219437\tK03504 POLD3; DNA polymerase delta subunit 3" }, { "name":"120113702 DNA polymerase delta subunit 4-like\tK03505 POLD4; DNA polymerase delta subunit 4" }, { "name":"120121461 uncharacterized protein LOC120121461\tK03505 POLD4; DNA polymerase delta subunit 4" }, { "name":"120123442 DNA polymerase delta subunit 4-like isoform X1\tK03505 POLD4; DNA polymerase delta subunit 4" }, { "name":"120129146 uncharacterized protein LOC120129146 isoform X1\tK03505 POLD4; DNA polymerase delta subunit 4" }, { "name":"120153976 uncharacterized protein LOC120153976\tK03505 POLD4; DNA polymerase delta subunit 4" }, { "name":"120170122 DNA polymerase delta subunit 4-like\tK03505 POLD4; DNA polymerase delta subunit 4" }, { "name":"120170130 DNA polymerase delta subunit 4-like\tK03505 POLD4; DNA polymerase delta subunit 4" } ] }, { "name":"DNA polymerase epsilon complex", "children":[ { "name":"120148367 LOW QUALITY PROTEIN: DNA polymerase epsilon catalytic subunit A-like\tK02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]" }, { "name":"120156933 LOW QUALITY PROTEIN: DNA polymerase epsilon catalytic subunit A-like\tK02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]" }, { "name":"120219071 DNA polymerase epsilon subunit B-like\tK02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]" }, { "name":"120131929 DNA polymerase epsilon subunit 3-like\tK02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]" } ] }, { "name":"120141994 proliferating cell nuclear antigen-like\tK04802 PCNA; proliferating cell nuclear antigen" }, { "name":"120142191 proliferating cell nuclear antigen-like\tK04802 PCNA; proliferating cell nuclear antigen" }, { "name":"120143105 proliferating cell nuclear antigen-like\tK04802 PCNA; proliferating cell nuclear antigen" }, { "name":"120158512 proliferating cell nuclear antigen-like\tK04802 PCNA; proliferating cell nuclear antigen" }, { "name":"120160021 proliferating cell nuclear antigen-like\tK04802 PCNA; proliferating cell nuclear antigen" }, { "name":"120161675 proliferating cell nuclear antigen-like\tK04802 PCNA; proliferating cell nuclear antigen" }, { "name":"120167898 proliferating cell nuclear antigen\tK04802 PCNA; proliferating cell nuclear antigen" }, { "name":"120169677 proliferating cell nuclear antigen-like\tK04802 PCNA; proliferating cell nuclear antigen" }, { "name":"120170420 proliferating cell nuclear antigen-like\tK04802 PCNA; proliferating cell nuclear antigen" }, { "name":"120171552 proliferating cell nuclear antigen-like\tK04802 PCNA; proliferating cell nuclear antigen" }, { "name":"120171821 proliferating cell nuclear antigen-like\tK04802 PCNA; proliferating cell nuclear antigen" }, { "name":"120194275 proliferating cell nuclear antigen 2-like\tK04802 PCNA; proliferating cell nuclear antigen" }, { "name":"120199312 proliferating cell nuclear antigen-like\tK04802 PCNA; proliferating cell nuclear antigen" }, { "name":"120129034 flap endonuclease 1-like\tK04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]" }, { "name":"120181811 flap endonuclease 1-like\tK04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]" }, { "name":"120213108 flap endonuclease 1-like isoform X1\tK04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]" }, { "name":"120113512 DNA ligase 1-like\tK10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]" }, { "name":"120206322 DNA ligase 1-like\tK10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]" } ] }, { "name":"Short Patch-BER factors", "children":[ { "name":"120217898 DNA-repair protein XRCC1 isoform X1\tK10803 XRCC1; DNA-repair protein XRCC1" } ] }, { "name":"Other BER factors", "children":[ { "name":"120170593 tyrosyl-DNA phosphodiesterase 1-like\tK10862 TDP1; tyrosyl-DNA phosphodiesterase 1 [EC:3.1.4.-]" }, { "name":"120151012 transcription factor bHLH140 isoform X1\tK10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]" }, { "name":"120160502 polynucleotide 3'-phosphatase ZDP-like\tK08073 PNKP; bifunctional polynucleotide phosphatase\/kinase [EC:3.1.3.32 2.7.1.78]" }, { "name":"120149472 DNA polymerase lambda\tK03512 POLL; DNA polymerase lambda [EC:2.7.7.7 4.2.99.-]" }, { "name":"120143552 poly [ADP-ribose] polymerase 1 isoform X1\tK24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30]" }, { "name":"120158194 LOW QUALITY PROTEIN: poly [ADP-ribose] polymerase 1-like\tK24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30]" }, { "name":"120133058 poly [ADP-ribose] polymerase 2-like\tK28005 PARP2; poly [ADP-ribose] polymerase 2 [EC:2.4.2.30]" }, { "name":"120141153 poly [ADP-ribose] polymerase 2-like\tK28005 PARP2; poly [ADP-ribose] polymerase 2 [EC:2.4.2.30]" }, { "name":"120210611 LOW QUALITY PROTEIN: protein ADP-ribosyltransferase PARP3-like\tK10798 PARP3_4; protein mono-ADP-ribosyltransferase 3\/4 [EC:2.4.2.-]" } ] } ] }, { "name":"NER (nucleotide excision repair)", "children":[ { "name":"GGR (global genome repair) factors", "children":[ { "name":"XPC-HR23B-CETN2 complex", "children":[ { "name":"120161027 DNA repair protein RAD4 isoform X1\tK10838 XPC; xeroderma pigmentosum group C-complementing protein" }, { "name":"120162974 ubiquitin receptor RAD23c-like\tK10839 RAD23; UV excision repair protein RAD23" }, { "name":"120179714 ubiquitin receptor RAD23b-like isoform X1\tK10839 RAD23; UV excision repair protein RAD23" }, { "name":"120181184 ubiquitin receptor RAD23c-like isoform X1\tK10839 RAD23; UV excision repair protein RAD23" }, { "name":"120187549 ubiquitin receptor RAD23c-like isoform X1\tK10839 RAD23; UV excision repair protein RAD23" }, { "name":"120193352 ubiquitin receptor RAD23c-like isoform X1\tK10839 RAD23; UV excision repair protein RAD23" }, { "name":"120203789 ubiquitin receptor RAD23c-like isoform X1\tK10839 RAD23; UV excision repair protein RAD23" }, { "name":"120210307 ubiquitin receptor RAD23b-like isoform X1\tK10839 RAD23; UV excision repair protein RAD23" }, { "name":"120217760 ubiquitin receptor RAD23b-like\tK10839 RAD23; UV excision repair protein RAD23" }, { "name":"120217819 ubiquitin receptor RAD23b-like\tK10839 RAD23; UV excision repair protein RAD23" } ] }, { "name":"Cul4-DDB2 complex", "children":[ { "name":"120114829 RING-box protein 1a\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]" }, { "name":"120149883 RING-box protein 1a-like\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]" }, { "name":"120156633 RING-box protein 1a-like\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]" }, { "name":"120167838 RING-box protein 1a-like isoform X1\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]" }, { "name":"120179762 RING-box protein 1a-like\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]" }, { "name":"120193390 RING-box protein 1a-like\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]" }, { "name":"120211863 RING-box protein 1a-like\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]" }, { "name":"120218694 RING-box protein 1a-like\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]" }, { "name":"120119401 cullin-4-like\tK10609 CUL4; cullin 4" }, { "name":"120169965 cullin-4-like\tK10609 CUL4; cullin 4" }, { "name":"120170869 cullin-4-like\tK10609 CUL4; cullin 4" }, { "name":"120172955 cullin-4-like\tK10609 CUL4; cullin 4" }, { "name":"120210354 cullin-4-like\tK10609 CUL4; cullin 4" }, { "name":"120149435 LOW QUALITY PROTEIN: DNA damage-binding protein 1a-like\tK10610 DDB1; DNA damage-binding protein 1" }, { "name":"120143373 LOW QUALITY PROTEIN: protein DAMAGED DNA-BINDING 2\tK10140 DDB2; DNA damage-binding protein 2" } ] }, { "name":"NER4 complex", "children":[ { "name":"120114811 F-box\/LRR-repeat protein fbxl-1-like\tK15082 RAD7; DNA repair protein RAD7" }, { "name":"120148754 uncharacterized protein LOC120148754\tK15082 RAD7; DNA repair protein RAD7" }, { "name":"120167843 EIN3-binding F-box protein 1-like\tK15082 RAD7; DNA repair protein RAD7" }, { "name":"120192437 dynein regulatory complex subunit 6 isoform X1\tK15082 RAD7; DNA repair protein RAD7" }, { "name":"120168944 DNA repair protein RAD16-like\tK15083 RAD16; DNA repair protein RAD16" } ] } ] }, { "name":"TCR (transcription coupled repair) factors", "children":[ { "name":"DNA-directed RNA polymerase II complex", "children":[ { "name":"120141629 DNA-directed RNA polymerase II subunit RPB1-like\tK03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]" }, { "name":"120216257 LOW QUALITY PROTEIN: DNA-directed RNA polymerase II subunit RPB1-like\tK03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]" }, { "name":"120119357 DNA-directed RNA polymerase II subunit RPB2-like\tK03010 RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]" }, { "name":"120217215 DNA-directed RNA polymerase II subunit RPB2\tK03010 RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]" }, { "name":"120117027 DNA-directed RNA polymerases II, IV and V subunit 3-like\tK03011 RPB3; DNA-directed RNA polymerase II subunit RPB3" }, { "name":"120142709 DNA-directed RNA polymerases II, IV and V subunit 3\tK03011 RPB3; DNA-directed RNA polymerase II subunit RPB3" }, { "name":"120119155 DNA-directed RNA polymerases IV and V subunit 4-like isoform X1\tK03012 RPB4; DNA-directed RNA polymerase II subunit RPB4" }, { "name":"120146967 DNA-directed RNA polymerases IV and V subunit 4-like isoform X1\tK03012 RPB4; DNA-directed RNA polymerase II subunit RPB4" }, { "name":"120159744 DNA-directed RNA polymerase II subunit 4\tK03012 RPB4; DNA-directed RNA polymerase II subunit RPB4" }, { "name":"120185624 DNA-directed RNA polymerase II subunit 4-like\tK03012 RPB4; DNA-directed RNA polymerase II subunit RPB4" }, { "name":"120212598 DNA-directed RNA polymerase II subunit 4-like\tK03012 RPB4; DNA-directed RNA polymerase II subunit RPB4" }, { "name":"120134000 DNA-directed RNA polymerases II and IV subunit 5A-like\tK03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1" }, { "name":"120144513 DNA-directed RNA polymerases II and IV subunit 5A\tK03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1" }, { "name":"120146602 DNA-directed RNA polymerase V subunit 5A-like isoform X1\tK03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1" }, { "name":"120189876 DNA-directed RNA polymerases II and IV subunit 5A-like\tK03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1" }, { "name":"120208919 DNA-directed RNA polymerase V subunit 5A-like\tK03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1" }, { "name":"120210607 DNA-directed RNA polymerases II and IV subunit 5A-like\tK03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1" }, { "name":"120118684 DNA-directed RNA polymerases II, IV and V subunit 6A-like\tK03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2" }, { "name":"120139916 DNA-directed RNA polymerases II, IV and V subunit 6A-like\tK03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2" }, { "name":"120140403 DNA-directed RNA polymerases II, IV and V subunit 6A-like\tK03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2" }, { "name":"120167004 DNA-directed RNA polymerases II, IV and V subunit 6A-like\tK03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2" }, { "name":"120172177 DNA-directed RNA polymerases II, IV and V subunit 6A-like\tK03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2" }, { "name":"120136628 DNA-directed RNA polymerase II subunit RPB7-like\tK03015 RPB7; DNA-directed RNA polymerase II subunit RPB7" }, { "name":"120165777 DNA-directed RNA polymerase II subunit RPB7-like\tK03015 RPB7; DNA-directed RNA polymerase II subunit RPB7" }, { "name":"120170266 DNA-directed RNA polymerase II subunit RPB7-like\tK03015 RPB7; DNA-directed RNA polymerase II subunit RPB7" }, { "name":"120189261 DNA-directed RNA polymerase II subunit RPB7\tK03015 RPB7; DNA-directed RNA polymerase II subunit RPB7" }, { "name":"120127893 DNA-directed RNA polymerases II, IV and V subunit 8B-like\tK03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3" }, { "name":"120143465 DNA-directed RNA polymerases II, IV and V subunit 8B-like\tK03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3" }, { "name":"120176070 DNA-directed RNA polymerases II, IV and V subunit 8B-like\tK03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3" }, { "name":"120219412 DNA-directed RNA polymerases II, IV and V subunit 8B-like\tK03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3" }, { "name":"120119968 DNA-directed RNA polymerases II, IV and V subunit 9A-like\tK03017 RPB9; DNA-directed RNA polymerase II subunit RPB9" }, { "name":"120123833 DNA-directed RNA polymerases II, IV and V subunit 9A\tK03017 RPB9; DNA-directed RNA polymerase II subunit RPB9" }, { "name":"120127792 DNA-directed RNA polymerases II, IV and V subunit 9A-like\tK03017 RPB9; DNA-directed RNA polymerase II subunit RPB9" }, { "name":"120176066 DNA-directed RNA polymerases II, IV and V subunit 9A\tK03017 RPB9; DNA-directed RNA polymerase II subunit RPB9" }, { "name":"120167111 DNA-directed RNA polymerase subunit 10-like protein\tK03007 RPABC5; DNA-directed RNA polymerases I, II, and III subunit RPABC5" }, { "name":"120202000 DNA-directed RNA polymerases I, II, and III subunit RPABC5\tK03007 RPABC5; DNA-directed RNA polymerases I, II, and III subunit RPABC5" }, { "name":"120216094 DNA-directed RNA polymerases I, II, and III subunit RPABC5\tK03007 RPABC5; DNA-directed RNA polymerases I, II, and III subunit RPABC5" }, { "name":"120136704 DNA-directed RNA polymerases II, IV and V subunit 11\tK03008 RPB11; DNA-directed RNA polymerase II subunit RPB11" }, { "name":"120165318 DNA-directed RNA polymerases II, IV and V subunit 11\tK03008 RPB11; DNA-directed RNA polymerase II subunit RPB11" }, { "name":"120188609 DNA-directed RNA polymerases II, IV and V subunit 11\tK03008 RPB11; DNA-directed RNA polymerase II subunit RPB11" }, { "name":"120146915 DNA-directed RNA polymerases II, IV and V subunit 12-like\tK03009 RPABC4; DNA-directed RNA polymerases I, II, and III subunit RPABC4" }, { "name":"120204096 DNA-directed RNA polymerases II, IV and V subunit 12-like\tK03009 RPABC4; DNA-directed RNA polymerases I, II, and III subunit RPABC4" }, { "name":"120217173 DNA-directed RNA polymerases II, IV and V subunit 12\tK03009 RPABC4; DNA-directed RNA polymerases I, II, and III subunit RPABC4" } ] }, { "name":"Cul4-CSA complex", "children":[ { "name":"120114829 RING-box protein 1a\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]" }, { "name":"120149883 RING-box protein 1a-like\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]" }, { "name":"120156633 RING-box protein 1a-like\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]" }, { "name":"120167838 RING-box protein 1a-like isoform X1\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]" }, { "name":"120179762 RING-box protein 1a-like\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]" }, { "name":"120193390 RING-box protein 1a-like\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]" }, { "name":"120211863 RING-box protein 1a-like\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]" }, { "name":"120218694 RING-box protein 1a-like\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]" }, { "name":"120119401 cullin-4-like\tK10609 CUL4; cullin 4" }, { "name":"120169965 cullin-4-like\tK10609 CUL4; cullin 4" }, { "name":"120170869 cullin-4-like\tK10609 CUL4; cullin 4" }, { "name":"120172955 cullin-4-like\tK10609 CUL4; cullin 4" }, { "name":"120210354 cullin-4-like\tK10609 CUL4; cullin 4" }, { "name":"120149435 LOW QUALITY PROTEIN: DNA damage-binding protein 1a-like\tK10610 DDB1; DNA damage-binding protein 1" }, { "name":"120190963 WD repeat-containing protein ATCSA-1-like\tK10570 ERCC8; DNA excision repair protein ERCC-8" }, { "name":"120191384 WD repeat-containing protein ATCSA-1-like\tK10570 ERCC8; DNA excision repair protein ERCC-8" } ] }, { "name":"Other TCR factor", "children":[ { "name":"120121004 LOW QUALITY PROTEIN: protein CHROMATIN REMODELING 8-like\tK10841 ERCC6; DNA excision repair protein ERCC-6" }, { "name":"120153587 LOW QUALITY PROTEIN: protein CHROMATIN REMODELING 8-like\tK10841 ERCC6; DNA excision repair protein ERCC-6" }, { "name":"120121154 UV-stimulated scaffold protein A homolog\tK23720 UVSSA; UV-stimulated scaffold protein A" }, { "name":"120153501 UV-stimulated scaffold protein A homolog\tK23720 UVSSA; UV-stimulated scaffold protein A" }, { "name":"120200540 UV-stimulated scaffold protein A homolog\tK23720 UVSSA; UV-stimulated scaffold protein A" }, { "name":"120119848 transcription elongation factor 1 homolog\tK25829 ELOF1; transcription elongation factor 1" }, { "name":"120147369 transcription elongation factor 1 homolog\tK25829 ELOF1; transcription elongation factor 1" }, { "name":"120160523 transcription elongation factor 1 homolog\tK25829 ELOF1; transcription elongation factor 1" }, { "name":"120189218 transcription elongation factor 1 homolog\tK25829 ELOF1; transcription elongation factor 1" }, { "name":"120195968 transcription elongation factor 1 homolog\tK25829 ELOF1; transcription elongation factor 1" } ] } ] }, { "name":"TFIIH complex", "children":[ { "name":"120163573 general transcription and DNA repair factor IIH helicase subunit XPB1\tK10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]" }, { "name":"120185942 general transcription and DNA repair factor IIH helicase subunit XPB1-like\tK10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]" }, { "name":"120116393 general transcription and DNA repair factor IIH subunit TFB1-1-like isoform X1\tK03141 TFIIH1; transcription initiation factor TFIIH subunit 1" }, { "name":"120129694 general transcription and DNA repair factor IIH subunit TFB1-1-like isoform X1\tK03141 TFIIH1; transcription initiation factor TFIIH subunit 1" }, { "name":"120155535 general transcription factor IIH subunit 2-like\tK03142 TFIIH2; transcription initiation factor TFIIH subunit 2" }, { "name":"120168015 general transcription factor IIH subunit 2-like\tK03142 TFIIH2; transcription initiation factor TFIIH subunit 2" }, { "name":"120130042 general transcription and DNA repair factor IIH subunit TFB4-like isoform X1\tK03143 TFIIH3; transcription initiation factor TFIIH subunit 3" }, { "name":"120216939 LOW QUALITY PROTEIN: general transcription and DNA repair factor IIH subunit TFB4-like\tK03143 TFIIH3; transcription initiation factor TFIIH subunit 3" }, { "name":"120206052 general transcription and DNA repair factor IIH subunit TFB2-like\tK03144 TFIIH4; transcription initiation factor TFIIH subunit 4" }, { "name":"120214669 general transcription and DNA repair factor IIH subunit TFB2-like\tK03144 TFIIH4; transcription initiation factor TFIIH subunit 4" }, { "name":"120155132 general transcription and DNA repair factor IIH subunit TFB5\tK10845 TTDA; TFIIH basal transcription factor complex TTD-A subunit" }, { "name":"120135063 cyclin-dependent kinase D-3-like\tK02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]" }, { "name":"120178790 cyclin-dependent kinase D-1-like isoform X1\tK02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]" }, { "name":"120199799 cyclin-dependent kinase D-1-like\tK02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]" }, { "name":"120204594 cyclin-dependent kinase D-3-like isoform X1\tK02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]" }, { "name":"120210668 cyclin-dependent kinase D-3-like isoform X1\tK02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]" }, { "name":"120163315 cyclin-H1-1-like\tK06634 CCNH; cyclin H" }, { "name":"120167193 LOW QUALITY PROTEIN: cyclin-H1-1-like\tK06634 CCNH; cyclin H" }, { "name":"120120861 uncharacterized protein LOC120120861\tK10842 MNAT1; CDK-activating kinase assembly factor MAT1" }, { "name":"120130748 uncharacterized protein LOC120130748\tK10842 MNAT1; CDK-activating kinase assembly factor MAT1" }, { "name":"120160078 uncharacterized protein LOC120160078\tK10842 MNAT1; CDK-activating kinase assembly factor MAT1" } ] }, { "name":"RPA (replication factor A)", "children":[ { "name":"120115803 replication protein A 70 kDa DNA-binding subunit B-like\tK07466 RFA1; replication factor A1" }, { "name":"120158646 replication protein A 70 kDa DNA-binding subunit B-like\tK07466 RFA1; replication factor A1" }, { "name":"120162325 replication protein A 70 kDa DNA-binding subunit A-like\tK07466 RFA1; replication factor A1" }, { "name":"120164764 replication protein A 70 kDa DNA-binding subunit A-like\tK07466 RFA1; replication factor A1" }, { "name":"120166293 replication protein A 70 kDa DNA-binding subunit A-like\tK07466 RFA1; replication factor A1" }, { "name":"120174322 replication protein A 70 kDa DNA-binding subunit A-like\tK07466 RFA1; replication factor A1" }, { "name":"120192582 replication protein A 70 kDa DNA-binding subunit A-like isoform X1\tK07466 RFA1; replication factor A1" }, { "name":"120132079 replication protein A 32 kDa subunit A-like\tK10739 RFA2; replication factor A2" }, { "name":"120132289 replication protein A 32 kDa subunit B-like isoform X1\tK10739 RFA2; replication factor A2" }, { "name":"120132308 replication protein A 32 kDa subunit B-like isoform X1\tK10739 RFA2; replication factor A2" }, { "name":"120157040 replication protein A 32 kDa subunit B-like\tK10739 RFA2; replication factor A2" }, { "name":"120179086 replication protein A 32 kDa subunit B-like\tK10739 RFA2; replication factor A2" }, { "name":"120182152 replication protein A 32 kDa subunit B-like\tK10739 RFA2; replication factor A2" }, { "name":"120158111 replication protein A 14 kDa subunit B-like\tK10740 RPA3; replication factor A3" }, { "name":"120173191 replication protein A 14 kDa subunit B-like\tK10740 RPA3; replication factor A3" }, { "name":"120183892 replication protein A 14 kDa subunit B-like\tK10740 RPA3; replication factor A3" }, { "name":"120202702 replication protein A 14 kDa subunit B-like\tK10740 RPA3; replication factor A3" } ] }, { "name":"Other NER factors", "children":[ { "name":"120124689 DNA excision repair protein ERCC-1 isoform X1\tK10849 ERCC1; DNA excision repair protein ERCC-1" }, { "name":"120128832 DNA repair endonuclease UVH1-like\tK10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]" }, { "name":"120164381 DNA repair endonuclease UVH1-like\tK10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]" }, { "name":"120121740 LOW QUALITY PROTEIN: DNA repair protein UVH3-like\tK10846 ERCC5; DNA excision repair protein ERCC-5" }, { "name":"120147502 DNA repair protein UVH3-like\tK10846 ERCC5; DNA excision repair protein ERCC-5" }, { "name":"120113512 DNA ligase 1-like\tK10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]" }, { "name":"120206322 DNA ligase 1-like\tK10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]" }, { "name":"120171234 protein CIA1-like\tK24730 CIAO1; cytosolic iron-sulfur protein assembly protein CIAO1" }, { "name":"120180870 protein CIA1-like\tK24730 CIAO1; cytosolic iron-sulfur protein assembly protein CIAO1" }, { "name":"120181032 protein CIA1-like isoform X1\tK24730 CIAO1; cytosolic iron-sulfur protein assembly protein CIAO1" }, { "name":"120118917 protein AE7-like 1\tK26403 CIAO2; cytosolic iron-sulfur assembly component 2" }, { "name":"120121654 protein AE7-like 1\tK26403 CIAO2; cytosolic iron-sulfur assembly component 2" }, { "name":"120122415 protein AE7-like 1\tK26403 CIAO2; cytosolic iron-sulfur assembly component 2" }, { "name":"120129811 protein AE7-like\tK26403 CIAO2; cytosolic iron-sulfur assembly component 2" }, { "name":"120131175 cullin-3A-like\tK03869 CUL3; cullin 3" }, { "name":"120156451 cullin-3A-like\tK03869 CUL3; cullin 3" }, { "name":"120170975 cullin-3A\tK03869 CUL3; cullin 3" }, { "name":"120174684 cullin-3A-like\tK03869 CUL3; cullin 3" }, { "name":"120185207 cullin-3A-like\tK03869 CUL3; cullin 3" }, { "name":"120203318 cullin-3A-like\tK03869 CUL3; cullin 3" }, { "name":"120143310 elongin-C-like\tK03872 ELOC; elongin-C" }, { "name":"120161861 elongin-C-like\tK03872 ELOC; elongin-C" }, { "name":"120167988 elongin-C-like\tK03872 ELOC; elongin-C" }, { "name":"120144606 uncharacterized protein LOC120144606\tK03873 ELOB; elongin-B" }, { "name":"120159279 uncharacterized protein LOC120159279\tK03873 ELOB; elongin-B" }, { "name":"120140396 transcription elongation factor B polypeptide 3 isoform X1\tK15077 ELA1; elongin-A" } ] } ] }, { "name":"MMR (mismatch excision repair)", "children":[ { "name":"Mismatch and loop recognition factors", "children":[ { "name":"120210654 DNA mismatch repair protein MSH2-like\tK08735 MSH2; DNA mismatch repair protein MSH2" }, { "name":"120117989 LOW QUALITY PROTEIN: DNA mismatch repair protein MSH3-like\tK08736 MSH3; DNA mismatch repair protein MSH3" }, { "name":"120186672 LOW QUALITY PROTEIN: DNA mismatch repair protein MSH3-like\tK08736 MSH3; DNA mismatch repair protein MSH3" }, { "name":"120186242 LOW QUALITY PROTEIN: DNA mismatch repair protein MSH6-like\tK08737 MSH6; DNA mismatch repair protein MSH6" }, { "name":"120189105 LOW QUALITY PROTEIN: DNA mismatch repair protein MSH6-like\tK08737 MSH6; DNA mismatch repair protein MSH6" }, { "name":"120201737 DNA mismatch repair protein MSH7-like\tK08737 MSH6; DNA mismatch repair protein MSH6" } ] }, { "name":"MutL homologs", "children":[ { "name":"120120984 DNA mismatch repair protein MLH1-like\tK08734 MLH1; DNA mismatch repair protein MLH1" }, { "name":"120141448 DNA mismatch repair protein MLH1-like\tK08734 MLH1; DNA mismatch repair protein MLH1" }, { "name":"120152059 LOW QUALITY PROTEIN: DNA mismatch repair protein PMS1-like\tK10858 PMS2; DNA mismatch repair protein PMS2" }, { "name":"120173775 LOW QUALITY PROTEIN: DNA mismatch repair protein PMS1-like\tK10858 PMS2; DNA mismatch repair protein PMS2" }, { "name":"120118377 LOW QUALITY PROTEIN: DNA mismatch repair protein MLH3-like\tK08739 MLH3; DNA mismatch repair protein MLH3" } ] }, { "name":"DNA polymerase delta complex", "children":[ { "name":"120123266 LOW QUALITY PROTEIN: DNA polymerase delta catalytic subunit-like\tK02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]" }, { "name":"120169661 DNA polymerase delta small subunit-like\tK02328 POLD2; DNA polymerase delta subunit 2" }, { "name":"120177759 DNA polymerase delta small subunit-like\tK02328 POLD2; DNA polymerase delta subunit 2" }, { "name":"120143972 uncharacterized protein LOC120143972\tK03504 POLD3; DNA polymerase delta subunit 3" }, { "name":"120219437 uncharacterized protein LOC120219437\tK03504 POLD3; DNA polymerase delta subunit 3" }, { "name":"120113702 DNA polymerase delta subunit 4-like\tK03505 POLD4; DNA polymerase delta subunit 4" }, { "name":"120121461 uncharacterized protein LOC120121461\tK03505 POLD4; DNA polymerase delta subunit 4" }, { "name":"120123442 DNA polymerase delta subunit 4-like isoform X1\tK03505 POLD4; DNA polymerase delta subunit 4" }, { "name":"120129146 uncharacterized protein LOC120129146 isoform X1\tK03505 POLD4; DNA polymerase delta subunit 4" }, { "name":"120153976 uncharacterized protein LOC120153976\tK03505 POLD4; DNA polymerase delta subunit 4" }, { "name":"120170122 DNA polymerase delta subunit 4-like\tK03505 POLD4; DNA polymerase delta subunit 4" }, { "name":"120170130 DNA polymerase delta subunit 4-like\tK03505 POLD4; DNA polymerase delta subunit 4" } ] }, { "name":"RPA (replication factor A)", "children":[ { "name":"120115803 replication protein A 70 kDa DNA-binding subunit B-like\tK07466 RFA1; replication factor A1" }, { "name":"120158646 replication protein A 70 kDa DNA-binding subunit B-like\tK07466 RFA1; replication factor A1" }, { "name":"120162325 replication protein A 70 kDa DNA-binding subunit A-like\tK07466 RFA1; replication factor A1" }, { "name":"120164764 replication protein A 70 kDa DNA-binding subunit A-like\tK07466 RFA1; replication factor A1" }, { "name":"120166293 replication protein A 70 kDa DNA-binding subunit A-like\tK07466 RFA1; replication factor A1" }, { "name":"120174322 replication protein A 70 kDa DNA-binding subunit A-like\tK07466 RFA1; replication factor A1" }, { "name":"120192582 replication protein A 70 kDa DNA-binding subunit A-like isoform X1\tK07466 RFA1; replication factor A1" }, { "name":"120132079 replication protein A 32 kDa subunit A-like\tK10739 RFA2; replication factor A2" }, { "name":"120132289 replication protein A 32 kDa subunit B-like isoform X1\tK10739 RFA2; replication factor A2" }, { "name":"120132308 replication protein A 32 kDa subunit B-like isoform X1\tK10739 RFA2; replication factor A2" }, { "name":"120157040 replication protein A 32 kDa subunit B-like\tK10739 RFA2; replication factor A2" }, { "name":"120179086 replication protein A 32 kDa subunit B-like\tK10739 RFA2; replication factor A2" }, { "name":"120182152 replication protein A 32 kDa subunit B-like\tK10739 RFA2; replication factor A2" }, { "name":"120158111 replication protein A 14 kDa subunit B-like\tK10740 RPA3; replication factor A3" }, { "name":"120173191 replication protein A 14 kDa subunit B-like\tK10740 RPA3; replication factor A3" }, { "name":"120183892 replication protein A 14 kDa subunit B-like\tK10740 RPA3; replication factor A3" }, { "name":"120202702 replication protein A 14 kDa subunit B-like\tK10740 RPA3; replication factor A3" } ] }, { "name":"RFC (replication factor C)", "children":[ { "name":"120195781 LOW QUALITY PROTEIN: replication factor C subunit 1-like\tK10754 RFC1; replication factor C subunit 1" }, { "name":"120204352 LOW QUALITY PROTEIN: replication factor C subunit 1-like\tK10754 RFC1; replication factor C subunit 1" }, { "name":"120117412 replication factor C subunit 2\tK10755 RFC2_4; replication factor C subunit 2\/4" }, { "name":"120143126 replication factor C subunit 2-like isoform X1\tK10755 RFC2_4; replication factor C subunit 2\/4" }, { "name":"120169112 replication factor C subunit 4-like\tK10755 RFC2_4; replication factor C subunit 2\/4" }, { "name":"120181561 replication factor C subunit 4-like\tK10755 RFC2_4; replication factor C subunit 2\/4" }, { "name":"120199325 replication factor C subunit 2-like\tK10755 RFC2_4; replication factor C subunit 2\/4" }, { "name":"120121399 replication factor C subunit 3-like\tK10756 RFC3_5; replication factor C subunit 3\/5" }, { "name":"120123631 replication factor C subunit 3-like\tK10756 RFC3_5; replication factor C subunit 3\/5" }, { "name":"120129117 replication factor C subunit 3 isoform X1\tK10756 RFC3_5; replication factor C subunit 3\/5" }, { "name":"120130054 replication factor C subunit 3-like\tK10756 RFC3_5; replication factor C subunit 3\/5" }, { "name":"120141786 uncharacterized protein LOC120141786\tK10756 RFC3_5; replication factor C subunit 3\/5" }, { "name":"120153033 uncharacterized protein LOC120153033\tK10756 RFC3_5; replication factor C subunit 3\/5" }, { "name":"120154352 replication factor C subunit 5-like\tK10756 RFC3_5; replication factor C subunit 3\/5" }, { "name":"120163246 replication factor C subunit 3-like\tK10756 RFC3_5; replication factor C subunit 3\/5" }, { "name":"120180390 replication factor C subunit 5-like\tK10756 RFC3_5; replication factor C subunit 3\/5" }, { "name":"120183776 uncharacterized protein LOC120183776\tK10756 RFC3_5; replication factor C subunit 3\/5" }, { "name":"120195002 replication factor C subunit 3-like\tK10756 RFC3_5; replication factor C subunit 3\/5" }, { "name":"120200748 replication factor C subunit 3-like\tK10756 RFC3_5; replication factor C subunit 3\/5" } ] }, { "name":"Other MMR factors", "children":[ { "name":"120141994 proliferating cell nuclear antigen-like\tK04802 PCNA; proliferating cell nuclear antigen" }, { "name":"120142191 proliferating cell nuclear antigen-like\tK04802 PCNA; proliferating cell nuclear antigen" }, { "name":"120143105 proliferating cell nuclear antigen-like\tK04802 PCNA; proliferating cell nuclear antigen" }, { "name":"120158512 proliferating cell nuclear antigen-like\tK04802 PCNA; proliferating cell nuclear antigen" }, { "name":"120160021 proliferating cell nuclear antigen-like\tK04802 PCNA; proliferating cell nuclear antigen" }, { "name":"120161675 proliferating cell nuclear antigen-like\tK04802 PCNA; proliferating cell nuclear antigen" }, { "name":"120167898 proliferating cell nuclear antigen\tK04802 PCNA; proliferating cell nuclear antigen" }, { "name":"120169677 proliferating cell nuclear antigen-like\tK04802 PCNA; proliferating cell nuclear antigen" }, { "name":"120170420 proliferating cell nuclear antigen-like\tK04802 PCNA; proliferating cell nuclear antigen" }, { "name":"120171552 proliferating cell nuclear antigen-like\tK04802 PCNA; proliferating cell nuclear antigen" }, { "name":"120171821 proliferating cell nuclear antigen-like\tK04802 PCNA; proliferating cell nuclear antigen" }, { "name":"120194275 proliferating cell nuclear antigen 2-like\tK04802 PCNA; proliferating cell nuclear antigen" }, { "name":"120199312 proliferating cell nuclear antigen-like\tK04802 PCNA; proliferating cell nuclear antigen" }, { "name":"120166109 exonuclease 1-like\tK10746 EXO1; exonuclease 1 [EC:3.1.-.-]" }, { "name":"120170806 exonuclease 1-like\tK10746 EXO1; exonuclease 1 [EC:3.1.-.-]" }, { "name":"120172912 LOW QUALITY PROTEIN: exonuclease 1-like\tK10746 EXO1; exonuclease 1 [EC:3.1.-.-]" }, { "name":"120113512 DNA ligase 1-like\tK10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]" }, { "name":"120206322 DNA ligase 1-like\tK10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]" }, { "name":"120200652 LOW QUALITY PROTEIN: WD repeat-containing protein 76-like\tK24755 WDR76; WD repeat-containing protein 76" } ] } ] } ] }, { "name":"DSBR (double strand breaks repair)", "children":[ { "name":"HR (homologous recombination)", "children":[ { "name":"MRN(MRX) complex", "children":[ { "name":"120142210 double-strand break repair protein MRE11-like isoform X1\tK10865 MRE11; double-strand break repair protein MRE11" }, { "name":"120114162 DNA repair protein RAD50\tK10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]" }, { "name":"120128356 LOW QUALITY PROTEIN: DNA repair protein RAD50-like\tK10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]" }, { "name":"120186390 nijmegen breakage syndrome 1 protein-like\tK10867 NBN; nibrin" }, { "name":"120190131 nijmegen breakage syndrome 1 protein-like\tK10867 NBN; nibrin" } ] }, { "name":"BRCA1-core complex", "children":[ { "name":"120130567 BRCA1-associated RING domain protein 1-like\tK10683 BARD1; BRCA1-associated RING domain protein 1" }, { "name":"120134172 protein BREAST CANCER SUSCEPTIBILITY 1 homolog isoform X1\tK10683 BARD1; BRCA1-associated RING domain protein 1" }, { "name":"120149496 protein BREAST CANCER SUSCEPTIBILITY 1 homolog\tK10683 BARD1; BRCA1-associated RING domain protein 1" }, { "name":"120152982 BRCA1-associated RING domain protein 1-like\tK10683 BARD1; BRCA1-associated RING domain protein 1" }, { "name":"120153166 BRCA1-associated RING domain protein 1-like isoform X1\tK10683 BARD1; BRCA1-associated RING domain protein 1" }, { "name":"120165459 BRCA1-associated RING domain protein 1-like isoform X1\tK10683 BARD1; BRCA1-associated RING domain protein 1" } ] }, { "name":"BRCA1-A complex", "children":[ { "name":"120131967 uncharacterized protein LOC120131967\tK20776 BABAM; BRISC and BRCA1-A complex member 1" }, { "name":"120156834 uncharacterized protein LOC120156834\tK20776 BABAM; BRISC and BRCA1-A complex member 1" }, { "name":"120166657 uncharacterized protein LOC120166657\tK20776 BABAM; BRISC and BRCA1-A complex member 1" }, { "name":"120218716 uncharacterized protein LOC120218716\tK20776 BABAM; BRISC and BRCA1-A complex member 1" }, { "name":"120145828 BRISC and BRCA1-A complex member 2-like\tK12173 BRE; BRCA1-A complex subunit BRE" }, { "name":"120160186 BRISC and BRCA1-A complex member 2-like\tK12173 BRE; BRCA1-A complex subunit BRE" }, { "name":"120195279 BRISC and BRCA1-A complex member 2-like\tK12173 BRE; BRCA1-A complex subunit BRE" }, { "name":"120195798 lys-63-specific deubiquitinase BRCC36-like isoform X1\tK11864 BRCC3; BRCA1\/BRCA2-containing complex subunit 3 [EC:3.4.19.-]" }, { "name":"120217895 lys-63-specific deubiquitinase BRCC36-like isoform X1\tK11864 BRCC3; BRCA1\/BRCA2-containing complex subunit 3 [EC:3.4.19.-]" } ] }, { "name":"BRCA1-B complex", "children":[ { "name":"120128510 Fanconi anemia group J protein homolog\tK15362 BRIP1; fanconi anemia group J protein [EC:5.6.2.3]" }, { "name":"120216721 LOW QUALITY PROTEIN: regulator of telomere elongation helicase 1 homolog\tK15362 BRIP1; fanconi anemia group J protein [EC:5.6.2.3]" }, { "name":"120127436 BRCT domain-containing protein At4g02110-like isoform X1\tK10728 TOPBP1; topoisomerase (DNA) II binding protein 1" }, { "name":"120176311 BRCT domain-containing protein At4g02110-like\tK10728 TOPBP1; topoisomerase (DNA) II binding protein 1" }, { "name":"120201458 DNA topoisomerase 2-binding protein 1-like\tK10728 TOPBP1; topoisomerase (DNA) II binding protein 1" }, { "name":"120212230 LOW QUALITY PROTEIN: DNA topoisomerase 2-binding protein 1-A-like\tK10728 TOPBP1; topoisomerase (DNA) II binding protein 1" } ] }, { "name":"BRCA1-C complex", "children":[ { "name":"120142210 double-strand break repair protein MRE11-like isoform X1\tK10865 MRE11; double-strand break repair protein MRE11" }, { "name":"120114162 DNA repair protein RAD50\tK10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]" }, { "name":"120128356 LOW QUALITY PROTEIN: DNA repair protein RAD50-like\tK10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]" }, { "name":"120186390 nijmegen breakage syndrome 1 protein-like\tK10867 NBN; nibrin" }, { "name":"120190131 nijmegen breakage syndrome 1 protein-like\tK10867 NBN; nibrin" } ] }, { "name":"BRCA complex", "children":[ { "name":"120137337 protein BREAST CANCER SUSCEPTIBILITY 2 homolog B-like isoform X1\tK08775 BRCA2; breast cancer 2 susceptibility protein" }, { "name":"120166434 DNA repair protein RAD51 homolog\tK04482 RAD51; DNA repair protein RAD51" } ] }, { "name":"RecA family proteins", "children":[ { "name":"120166434 DNA repair protein RAD51 homolog\tK04482 RAD51; DNA repair protein RAD51" }, { "name":"120145495 DNA repair protein RAD51 homolog 2 isoform X1\tK10869 RAD51L1; RAD51-like protein 1" }, { "name":"120161151 DNA repair protein RAD51 homolog 3 isoform X1\tK10870 RAD51L2; RAD51-like protein 2" }, { "name":"120116672 DNA repair protein RAD51 homolog 4-like isoform X1\tK10871 RAD51L3; RAD51-like protein 3" }, { "name":"120134319 DNA repair protein XRCC2 homolog\tK10879 XRCC2; DNA-repair protein XRCC2" }, { "name":"120211476 DNA repair protein XRCC2 homolog\tK10879 XRCC2; DNA-repair protein XRCC2" }, { "name":"120157015 DNA repair protein XRCC3 homolog\tK10880 XRCC3; DNA-repair protein XRCC3" }, { "name":"120182166 DNA repair protein XRCC3 homolog\tK10880 XRCC3; DNA-repair protein XRCC3" } ] }, { "name":"Rad52 family proteins", "children":[ { "name":"120205402 LOW QUALITY PROTEIN: DNA repair RAD52-like protein 1, mitochondrial\tK26556 RAD52-1; DNA repair RAD52-like protein 1, mitochondrial" }, { "name":"120140198 DNA repair RAD52-like protein 2, chloroplastic\tK26558 RAD52-2; DNA repair RAD52-like protein 2, chloroplastic" }, { "name":"120144404 DNA repair RAD52-like protein 2, chloroplastic\tK26558 RAD52-2; DNA repair RAD52-like protein 2, chloroplastic" }, { "name":"120147619 DNA repair RAD52-like protein 2, chloroplastic\tK26558 RAD52-2; DNA repair RAD52-like protein 2, chloroplastic" }, { "name":"120166706 DNA repair RAD52-like protein 2, chloroplastic\tK26558 RAD52-2; DNA repair RAD52-like protein 2, chloroplastic" }, { "name":"120169337 DNA repair RAD52-like protein 2, chloroplastic\tK26558 RAD52-2; DNA repair RAD52-like protein 2, chloroplastic" } ] }, { "name":"Rad54 family proteins", "children":[ { "name":"120119670 protein CHROMATIN REMODELING 35-like isoform X1\tK10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]" }, { "name":"120123515 SNF2 domain-containing protein CLASSY 3-like\tK10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]" }, { "name":"120134504 protein CHROMATIN REMODELING 25-like\tK10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]" }, { "name":"120145526 LOW QUALITY PROTEIN: protein CHROMATIN REMODELING 25-like\tK10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]" }, { "name":"120151773 SNF2 domain-containing protein CLASSY 1-like\tK10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]" }, { "name":"120162082 SNF2 domain-containing protein CLASSY 3-like\tK10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]" }, { "name":"120179322 protein CHROMATIN REMODELING 35-like isoform X1\tK10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]" }, { "name":"120180626 SNF2 domain-containing protein CLASSY 3-like\tK10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]" }, { "name":"120190494 protein CHROMATIN REMODELING 35-like isoform X1\tK10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]" }, { "name":"120203409 protein CHROMATIN REMODELING 35-like\tK10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]" }, { "name":"120204177 SNF2 domain-containing protein CLASSY 1-like\tK10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]" }, { "name":"120217554 SNF2 domain-containing protein CLASSY 1-like\tK10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]" } ] }, { "name":"RecQ family DNA helicases", "children":[ { "name":"120133805 ATP-dependent DNA helicase Q-like 2 isoform X1\tK10899 RECQL; ATP-dependent DNA helicase Q1 [EC:5.6.2.4]" }, { "name":"120208795 ATP-dependent DNA helicase Q-like 1\tK10899 RECQL; ATP-dependent DNA helicase Q1 [EC:5.6.2.4]" }, { "name":"120163323 LOW QUALITY PROTEIN: ATP-dependent DNA helicase Q-like SIM\tK10900 WRN; werner syndrome ATP-dependent helicase [EC:5.6.2.4]" }, { "name":"120139034 ATP-dependent DNA helicase Q-like 3\tK10901 BLM; bloom syndrome protein [EC:5.6.2.4]" }, { "name":"120145031 LOW QUALITY PROTEIN: ATP-dependent DNA helicase Q-like 4A\tK10901 BLM; bloom syndrome protein [EC:5.6.2.4]" }, { "name":"120134391 ATP-dependent DNA helicase Q-like 5\tK10730 RECQL4; ATP-dependent DNA helicase Q4 [EC:5.6.2.4]" } ] }, { "name":"Bloom's syndrome complex (BTR)", "children":[ { "name":"120139034 ATP-dependent DNA helicase Q-like 3\tK10901 BLM; bloom syndrome protein [EC:5.6.2.4]" }, { "name":"120145031 LOW QUALITY PROTEIN: ATP-dependent DNA helicase Q-like 4A\tK10901 BLM; bloom syndrome protein [EC:5.6.2.4]" }, { "name":"120140968 LOW QUALITY PROTEIN: DNA topoisomerase 3-alpha\tK03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]" }, { "name":"120178316 DNA topoisomerase 3-beta-like isoform X1\tK03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]" }, { "name":"120117245 recQ-mediated genome instability protein 1-like\tK10990 RMI1; RecQ-mediated genome instability protein 1" }, { "name":"120161752 uncharacterized protein LOC120161752\tK15365 RMI2; RecQ-mediated genome instability protein 2" }, { "name":"120210015 uncharacterized protein LOC120210015\tK15365 RMI2; RecQ-mediated genome instability protein 2" } ] }, { "name":"RPA (replication factor A)", "children":[ { "name":"120115803 replication protein A 70 kDa DNA-binding subunit B-like\tK07466 RFA1; replication factor A1" }, { "name":"120158646 replication protein A 70 kDa DNA-binding subunit B-like\tK07466 RFA1; replication factor A1" }, { "name":"120162325 replication protein A 70 kDa DNA-binding subunit A-like\tK07466 RFA1; replication factor A1" }, { "name":"120164764 replication protein A 70 kDa DNA-binding subunit A-like\tK07466 RFA1; replication factor A1" }, { "name":"120166293 replication protein A 70 kDa DNA-binding subunit A-like\tK07466 RFA1; replication factor A1" }, { "name":"120174322 replication protein A 70 kDa DNA-binding subunit A-like\tK07466 RFA1; replication factor A1" }, { "name":"120192582 replication protein A 70 kDa DNA-binding subunit A-like isoform X1\tK07466 RFA1; replication factor A1" }, { "name":"120132079 replication protein A 32 kDa subunit A-like\tK10739 RFA2; replication factor A2" }, { "name":"120132289 replication protein A 32 kDa subunit B-like isoform X1\tK10739 RFA2; replication factor A2" }, { "name":"120132308 replication protein A 32 kDa subunit B-like isoform X1\tK10739 RFA2; replication factor A2" }, { "name":"120157040 replication protein A 32 kDa subunit B-like\tK10739 RFA2; replication factor A2" }, { "name":"120179086 replication protein A 32 kDa subunit B-like\tK10739 RFA2; replication factor A2" }, { "name":"120182152 replication protein A 32 kDa subunit B-like\tK10739 RFA2; replication factor A2" }, { "name":"120158111 replication protein A 14 kDa subunit B-like\tK10740 RPA3; replication factor A3" }, { "name":"120173191 replication protein A 14 kDa subunit B-like\tK10740 RPA3; replication factor A3" }, { "name":"120183892 replication protein A 14 kDa subunit B-like\tK10740 RPA3; replication factor A3" }, { "name":"120202702 replication protein A 14 kDa subunit B-like\tK10740 RPA3; replication factor A3" } ] }, { "name":"Protein phosphatase 4", "children":[ { "name":"120141627 serine\/threonine-protein phosphatase PP-X isozyme 2\tK15423 PPP4C; serine\/threonine-protein phosphatase 4 catalytic subunit [EC:3.1.3.16]" }, { "name":"120127040 serine\/threonine-protein phosphatase 4 regulatory subunit 2-like isoform X1\tK15425 PPP4R2; serine\/threonine-protein phosphatase 4 regulatory subunit 2" }, { "name":"120163864 uncharacterized protein LOC120163864 isoform X1\tK15425 PPP4R2; serine\/threonine-protein phosphatase 4 regulatory subunit 2" }, { "name":"120114834 serine\/threonine-protein phosphatase 4 regulatory subunit 3B-like isoform X1\tK17491 SMEK; protein phosphatase 4 regulatory subunit 3" }, { "name":"120114949 serine\/threonine-protein phosphatase 4 regulatory subunit 3B-like\tK17491 SMEK; protein phosphatase 4 regulatory subunit 3" }, { "name":"120134969 serine\/threonine-protein phosphatase 4 regulatory subunit 3-like\tK17491 SMEK; protein phosphatase 4 regulatory subunit 3" }, { "name":"120178534 serine\/threonine-protein phosphatase 4 regulatory subunit 3-like isoform X1\tK17491 SMEK; protein phosphatase 4 regulatory subunit 3" }, { "name":"120213886 serine\/threonine-protein phosphatase 4 regulatory subunit 3-like isoform X1\tK17491 SMEK; protein phosphatase 4 regulatory subunit 3" } ] }, { "name":"AP-5 complex", "children":[ { "name":"120150409 uncharacterized protein LOC120150409\tK19022 AP5B1; AP-5 complex subunit beta-1" }, { "name":"120169897 uncharacterized protein LOC120169897 isoform X1\tK19022 AP5B1; AP-5 complex subunit beta-1" }, { "name":"120183282 uncharacterized protein LOC120183282\tK19022 AP5B1; AP-5 complex subunit beta-1" }, { "name":"120136977 LOW QUALITY PROTEIN: AP-5 complex subunit mu-like\tK19023 AP5M1; AP-5 complex subunit mu-1" }, { "name":"120208320 AP-5 complex subunit mu-like\tK19023 AP5M1; AP-5 complex subunit mu-1" }, { "name":"120219491 AP-5 complex subunit zeta-1-like isoform X1\tK19025 AP5Z1; AP-5 complex subunit zeta-1" } ] }, { "name":"SMC5-SMC6 complex", "children":[ { "name":"120162121 structural maintenance of chromosomes protein 5-like\tK22803 SMC5; structural maintenance of chromosomes protein 5" }, { "name":"120164587 structural maintenance of chromosomes protein 5-like\tK22803 SMC5; structural maintenance of chromosomes protein 5" }, { "name":"120210052 structural maintenance of chromosomes protein 6B-like\tK22804 SMC6; structural maintenance of chromosomes protein 6" }, { "name":"120119411 non-structural maintenance of chromosomes element 1 homolog\tK22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27]" }, { "name":"120174960 non-structural maintenance of chromosomes element 1 homolog\tK22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27]" }, { "name":"120182686 non-structural maintenance of chromosomes element 1 homolog isoform X1\tK22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27]" }, { "name":"120127708 E3 SUMO-protein ligase MMS21\tK22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]" }, { "name":"120164883 E3 SUMO-protein ligase MMS21-like\tK22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]" }, { "name":"120150243 non-structural maintenance of chromosomes element 4 homolog A\tK22825 NSMCE4; non-structural maintenance of chromosomes element 4" }, { "name":"120211054 non-structural maintenance of chromosomes element 4 homolog A-like\tK22825 NSMCE4; non-structural maintenance of chromosomes element 4" } ] }, { "name":"Other HR factors", "children":[ { "name":"120159733 crossover junction endonuclease EME1B-like isoform X1\tK10882 EME1; crossover junction endonuclease EME1 [EC:3.1.22.-]" }, { "name":"120151303 crossover junction endonuclease MUS81-like isoform X1\tK08991 MUS81; crossover junction endonuclease MUS81 [EC:3.1.22.-]" }, { "name":"120161883 LOW QUALITY PROTEIN: crossover junction endonuclease MUS81-like\tK08991 MUS81; crossover junction endonuclease MUS81 [EC:3.1.22.-]" }, { "name":"120117104 protein DSS1 HOMOLOG ON CHROMOSOME V-like\tK10881 SHFM1; 26 proteasome complex subunit DSS1" }, { "name":"120135719 protein DSS1 HOMOLOG ON CHROMOSOME V-like\tK10881 SHFM1; 26 proteasome complex subunit DSS1" }, { "name":"120140072 protein DSS1 HOMOLOG ON CHROMOSOME V-like\tK10881 SHFM1; 26 proteasome complex subunit DSS1" }, { "name":"120192078 protein DSS1 HOMOLOG ON CHROMOSOME V-like\tK10881 SHFM1; 26 proteasome complex subunit DSS1" }, { "name":"120204562 protein DELETION OF SUV3 SUPPRESSOR 1(I)-like\tK10881 SHFM1; 26 proteasome complex subunit DSS1" }, { "name":"120214044 protein DSS1 HOMOLOG ON CHROMOSOME V-like\tK10881 SHFM1; 26 proteasome complex subunit DSS1" }, { "name":"120157329 uncharacterized protein LOC120157329\tK15078 SLX1; structure-specific endonuclease subunit SLX1 [EC:3.6.1.-]" }, { "name":"120179913 structure-specific endonuclease subunit slx1-like\tK15078 SLX1; structure-specific endonuclease subunit SLX1 [EC:3.6.1.-]" }, { "name":"120188694 structure-specific endonuclease subunit slx1-like\tK15078 SLX1; structure-specific endonuclease subunit SLX1 [EC:3.6.1.-]" }, { "name":"120212918 uncharacterized protein LOC120212918\tK15078 SLX1; structure-specific endonuclease subunit SLX1 [EC:3.6.1.-]" }, { "name":"120125121 single-strand DNA endonuclease 1\tK15338 GEN1; holliday junction resolvase GEN1\/YEN1 [EC:3.1.-.-]" }, { "name":"120122919 uncharacterized protein LOC120122919\tK19026 SPG11; spatacsin" }, { "name":"120125556 uncharacterized protein LOC120125556 isoform X1\tK19026 SPG11; spatacsin" }, { "name":"120130459 uncharacterized protein LOC120130459\tK19026 SPG11; spatacsin" }, { "name":"120166661 LOW QUALITY PROTEIN: uncharacterized protein LOC120166661\tK19027 ZFYVE26; zinc finger FYVE domain-containing protein 26" }, { "name":"120218883 LOW QUALITY PROTEIN: uncharacterized protein LOC120218883\tK19027 ZFYVE26; zinc finger FYVE domain-containing protein 26" }, { "name":"120136081 protein MRG1-like\tK11339 MORF4L1; mortality factor 4-like protein 1" }, { "name":"120159660 protein MRG1-like\tK11339 MORF4L1; mortality factor 4-like protein 1" }, { "name":"120168307 protein MRG2-like isoform X1\tK11339 MORF4L1; mortality factor 4-like protein 1" }, { "name":"120181444 protein MRG1-like\tK11339 MORF4L1; mortality factor 4-like protein 1" }, { "name":"120191432 protein MRG1-like\tK11339 MORF4L1; mortality factor 4-like protein 1" }, { "name":"120194141 protein MRG1-like\tK11339 MORF4L1; mortality factor 4-like protein 1" }, { "name":"120125274 deoxynucleoside triphosphate triphosphohydrolase SAMHD1 homolog\tK22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-]" }, { "name":"120136170 deoxynucleoside triphosphate triphosphohydrolase SAMHD1 homolog\tK22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-]" }, { "name":"120181629 deoxynucleoside triphosphate triphosphohydrolase SAMHD1 homolog\tK22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-]" }, { "name":"120215261 LOW QUALITY PROTEIN: deoxynucleoside triphosphate triphosphohydrolase SAMHD1 homolog\tK22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-]" }, { "name":"120140368 ATPase family AAA domain-containing protein FIGL1-like\tK22766 FIGNL1; fidgetin-like protein 1 [EC:5.6.2.-]" }, { "name":"120178254 zinc finger SWIM domain-containing protein 7-like\tK25770 ZSWIM7; zinc finger SWIM domain-containing protein 7" }, { "name":"120117169 homologous recombination OB-fold protein\tK27803 HROB; homologous recombination OB-fold protein" }, { "name":"120146059 LOW QUALITY PROTEIN: probable DNA helicase MCM8\tK10737 MCM8; DNA helicase MCM8 [EC:5.6.2.4]" }, { "name":"120114212 probable DNA helicase MCM9\tK10738 MCM9; DNA helicase MCM9 [EC:5.6.2.4]" }, { "name":"120120323 probable DNA helicase MCM9\tK10738 MCM9; DNA helicase MCM9 [EC:5.6.2.4]" }, { "name":"120191244 MRN complex-interacting protein-like\tK28623 MRNIP; MRN complex-interacting protein" }, { "name":"120218654 MRN complex-interacting protein-like\tK28623 MRNIP; MRN complex-interacting protein" }, { "name":"120121909 uncharacterized protein LOC120121909 isoform X1\tK22685 WSS1; DNA-dependent metalloprotease WSS1 [EC:3.4.24.-]" }, { "name":"120123321 LOW QUALITY PROTEIN: DNA-dependent metalloprotease WSS1-like\tK22685 WSS1; DNA-dependent metalloprotease WSS1 [EC:3.4.24.-]" }, { "name":"120141527 uncharacterized protein LOC120141527\tK22685 WSS1; DNA-dependent metalloprotease WSS1 [EC:3.4.24.-]" }, { "name":"120161559 DNA-dependent metalloprotease WSS1-like\tK22685 WSS1; DNA-dependent metalloprotease WSS1 [EC:3.4.24.-]" }, { "name":"120174673 single-stranded DNA-binding protein WHY1, chloroplastic-like\tK26559 WHY1; single-stranded DNA-binding protein WHY1" }, { "name":"120175298 single-stranded DNA-binding protein WHY1, chloroplastic-like\tK26559 WHY1; single-stranded DNA-binding protein WHY1" }, { "name":"120185203 single-stranded DNA-binding protein WHY1, chloroplastic-like isoform X1\tK26559 WHY1; single-stranded DNA-binding protein WHY1" }, { "name":"120144652 LOW QUALITY PROTEIN: single-stranded DNA-binding protein WHY2, mitochondrial-like\tK26561 WHY2; single-stranded DNA-binding protein WHY2" }, { "name":"120174125 single-stranded DNA-binding protein WHY2, mitochondrial-like\tK26561 WHY2; single-stranded DNA-binding protein WHY2" } ] } ] }, { "name":"NHEJ (non-homologous end-joining)", "children":[ { "name":"DNA-PK complex", "children":[ { "name":"120114143 ATP-dependent DNA helicase 2 subunit KU70\tK10884 XRCC6; ATP-dependent DNA helicase 2 subunit 1" }, { "name":"120136110 ATP-dependent DNA helicase 2 subunit KU80\tK10885 XRCC5; ATP-dependent DNA helicase 2 subunit 2" } ] }, { "name":"MRX complex", "children":[ { "name":"120142210 double-strand break repair protein MRE11-like isoform X1\tK10865 MRE11; double-strand break repair protein MRE11" }, { "name":"120114162 DNA repair protein RAD50\tK10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]" }, { "name":"120128356 LOW QUALITY PROTEIN: DNA repair protein RAD50-like\tK10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]" } ] }, { "name":"DNA Ligase 4 complex", "children":[ { "name":"120165384 DNA ligase 4-like isoform X1\tK10777 LIG4; DNA ligase 4 [EC:6.5.1.1]" }, { "name":"120145744 DNA repair protein XRCC4-like\tK10886 XRCC4; DNA-repair protein XRCC4" }, { "name":"120183320 DNA repair protein XRCC4-like\tK10886 XRCC4; DNA-repair protein XRCC4" }, { "name":"120189648 DNA repair protein XRCC4-like\tK10886 XRCC4; DNA-repair protein XRCC4" } ] }, { "name":"X-family DNA polymerases", "children":[ { "name":"120149472 DNA polymerase lambda\tK03512 POLL; DNA polymerase lambda [EC:2.7.7.7 4.2.99.-]" } ] }, { "name":"Other NHEJ factors", "children":[ { "name":"120151012 transcription factor bHLH140 isoform X1\tK10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]" }, { "name":"120146867 structural maintenance of chromosomes flexible hinge domain-containing protein GMI1-like\tK23113 SMCHD1; structural maintenance of chromosomes flexible hinge domain-containing protein 1" }, { "name":"120200116 structural maintenance of chromosomes flexible hinge domain-containing protein GMI1-like isoform X1\tK23113 SMCHD1; structural maintenance of chromosomes flexible hinge domain-containing protein 1" }, { "name":"120207015 LOW QUALITY PROTEIN: structural maintenance of chromosomes flexible hinge domain-containing protein GMI1-like\tK23113 SMCHD1; structural maintenance of chromosomes flexible hinge domain-containing protein 1" } ] } ] }, { "name":"FA (Fanconi anemia) pathway", "children":[ { "name":"FA core complex", "children":[ { "name":"120216326 E3 ubiquitin-protein ligase FANCL-like isoform X1\tK10606 FANCL; E3 ubiquitin-protein ligase FANCL [EC:2.3.2.27]" }, { "name":"120121088 DEAD-box ATP-dependent RNA helicase FANCM-like isoform X1\tK10896 FANCM; fanconi anemia group M protein" }, { "name":"120141414 DEAD-box ATP-dependent RNA helicase FANCM-like\tK10896 FANCM; fanconi anemia group M protein" } ] }, { "name":"FA core complex binding factors", "children":[ { "name":"120117254 protein MHF1 homolog isoform X1\tK11511 APITD1; centromere protein S" }, { "name":"120122152 protein MHF1 homolog\tK11511 APITD1; centromere protein S" }, { "name":"120149289 protein MHF1 homolog\tK11511 APITD1; centromere protein S" }, { "name":"120170423 protein MHF1 homolog\tK11511 APITD1; centromere protein S" }, { "name":"120177307 protein MHF1 homolog\tK11511 APITD1; centromere protein S" }, { "name":"120155026 protein MHF2 homolog\tK15360 STRA13; centromere protein X" }, { "name":"120178383 protein MHF2 homolog isoform X1\tK15360 STRA13; centromere protein X" }, { "name":"120184836 protein MHF2 homolog isoform X1\tK15360 STRA13; centromere protein X" }, { "name":"120187265 protein MHF2 homolog isoform X1\tK15360 STRA13; centromere protein X" }, { "name":"120191975 protein MHF2 homolog\tK15360 STRA13; centromere protein X" }, { "name":"120156724 probable ubiquitin-conjugating enzyme E2 37\tK13960 UBE2T; ubiquitin-conjugating enzyme E2 T [EC:2.3.2.23]" }, { "name":"120201960 probable ubiquitin-conjugating enzyme E2 37\tK13960 UBE2T; ubiquitin-conjugating enzyme E2 T [EC:2.3.2.23]" } ] }, { "name":"Bloom's syndrome complex (BTR)", "children":[ { "name":"120139034 ATP-dependent DNA helicase Q-like 3\tK10901 BLM; bloom syndrome protein [EC:5.6.2.4]" }, { "name":"120145031 LOW QUALITY PROTEIN: ATP-dependent DNA helicase Q-like 4A\tK10901 BLM; bloom syndrome protein [EC:5.6.2.4]" }, { "name":"120140968 LOW QUALITY PROTEIN: DNA topoisomerase 3-alpha\tK03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]" }, { "name":"120178316 DNA topoisomerase 3-beta-like isoform X1\tK03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]" }, { "name":"120117245 recQ-mediated genome instability protein 1-like\tK10990 RMI1; RecQ-mediated genome instability protein 1" }, { "name":"120161752 uncharacterized protein LOC120161752\tK15365 RMI2; RecQ-mediated genome instability protein 2" }, { "name":"120210015 uncharacterized protein LOC120210015\tK15365 RMI2; RecQ-mediated genome instability protein 2" } ] }, { "name":"FANCD2-I complex", "children":[ { "name":"120152345 LOW QUALITY PROTEIN: Fanconi anemia group D2 protein homolog\tK10891 FANCD2; fanconi anemia group D2 protein" }, { "name":"120152599 Fanconi anemia group I protein\tK10895 FANCI; fanconi anemia group I protein" } ] }, { "name":"Downstream FA components", "children":[ { "name":"120137337 protein BREAST CANCER SUSCEPTIBILITY 2 homolog B-like isoform X1\tK08775 BRCA2; breast cancer 2 susceptibility protein" }, { "name":"120128510 Fanconi anemia group J protein homolog\tK15362 BRIP1; fanconi anemia group J protein [EC:5.6.2.3]" }, { "name":"120216721 LOW QUALITY PROTEIN: regulator of telomere elongation helicase 1 homolog\tK15362 BRIP1; fanconi anemia group J protein [EC:5.6.2.3]" } ] }, { "name":"Other FA pathway factors", "children":[ { "name":"120166434 DNA repair protein RAD51 homolog\tK04482 RAD51; DNA repair protein RAD51" }, { "name":"120161151 DNA repair protein RAD51 homolog 3 isoform X1\tK10870 RAD51L2; RAD51-like protein 2" }, { "name":"120148074 telomere length regulation protein TEL2 homolog\tK11137 TELO2; telomere length regulation protein" }, { "name":"120116179 WD repeat-containing protein 48-like\tK15361 WDR48; WD repeat-containing protein 48" }, { "name":"120117840 WD repeat-containing protein 48-like\tK15361 WDR48; WD repeat-containing protein 48" }, { "name":"120138868 WD repeat-containing protein 48-like\tK15361 WDR48; WD repeat-containing protein 48" }, { "name":"120163255 WD repeat-containing protein 48-like isoform X1\tK15361 WDR48; WD repeat-containing protein 48" }, { "name":"120193873 WD repeat-containing protein 48-like\tK15361 WDR48; WD repeat-containing protein 48" } ] } ] }, { "name":"Other DSBR factors", "children":[ { "name":"Protein phosphatase 6", "children":[ { "name":"120127988 phytochrome-associated serine\/threonine-protein phosphatase\tK15498 PPP6C; serine\/threonine-protein phosphatase 6 catalytic subunit [EC:3.1.3.16]" }, { "name":"120142719 phytochrome-associated serine\/threonine-protein phosphatase-like\tK15498 PPP6C; serine\/threonine-protein phosphatase 6 catalytic subunit [EC:3.1.3.16]" }, { "name":"120150908 phytochrome-associated serine\/threonine-protein phosphatase-like\tK15498 PPP6C; serine\/threonine-protein phosphatase 6 catalytic subunit [EC:3.1.3.16]" }, { "name":"120167881 phytochrome-associated serine\/threonine-protein phosphatase-like\tK15498 PPP6C; serine\/threonine-protein phosphatase 6 catalytic subunit [EC:3.1.3.16]" }, { "name":"120175523 phytochrome-associated serine\/threonine-protein phosphatase 3-like\tK15498 PPP6C; serine\/threonine-protein phosphatase 6 catalytic subunit [EC:3.1.3.16]" }, { "name":"120188413 phytochrome-associated serine\/threonine-protein phosphatase-like\tK15498 PPP6C; serine\/threonine-protein phosphatase 6 catalytic subunit [EC:3.1.3.16]" }, { "name":"120214988 phytochrome-associated serine\/threonine-protein phosphatase-like\tK15498 PPP6C; serine\/threonine-protein phosphatase 6 catalytic subunit [EC:3.1.3.16]" }, { "name":"120115345 serine\/threonine-protein phosphatase 6 regulatory subunit 3-like\tK15501 PPP6R3; serine\/threonine-protein phosphatase 6 regulatory subunit 3" }, { "name":"120131305 serine\/threonine-protein phosphatase 6 regulatory subunit 3-like isoform X1\tK15501 PPP6R3; serine\/threonine-protein phosphatase 6 regulatory subunit 3" }, { "name":"120148342 serine\/threonine-protein phosphatase 6 regulatory subunit 3-like\tK15501 PPP6R3; serine\/threonine-protein phosphatase 6 regulatory subunit 3" }, { "name":"120156244 serine\/threonine-protein phosphatase 6 regulatory subunit 3-like isoform X1\tK15501 PPP6R3; serine\/threonine-protein phosphatase 6 regulatory subunit 3" }, { "name":"120162406 serine\/threonine-protein phosphatase 6 regulatory subunit 3-like isoform X1\tK15501 PPP6R3; serine\/threonine-protein phosphatase 6 regulatory subunit 3" }, { "name":"120174837 serine\/threonine-protein phosphatase 6 regulatory subunit 2-like\tK15501 PPP6R3; serine\/threonine-protein phosphatase 6 regulatory subunit 3" }, { "name":"120191865 serine\/threonine-protein phosphatase 6 regulatory subunit 2-like isoform X1\tK15501 PPP6R3; serine\/threonine-protein phosphatase 6 regulatory subunit 3" }, { "name":"120194024 serine\/threonine-protein phosphatase 6 regulatory subunit 2-like isoform X1\tK15501 PPP6R3; serine\/threonine-protein phosphatase 6 regulatory subunit 3" }, { "name":"120203255 serine\/threonine-protein phosphatase 6 regulatory subunit 3-like isoform X1\tK15501 PPP6R3; serine\/threonine-protein phosphatase 6 regulatory subunit 3" } ] }, { "name":"Ubiquitin ligases" }, { "name":"Others", "children":[ { "name":"120190512 telomerase Cajal body protein 1-like\tK23314 WRAP53; telomerase Cajal body protein 1" }, { "name":"120194636 telomerase Cajal body protein 1-like\tK23314 WRAP53; telomerase Cajal body protein 1" }, { "name":"120127116 WD repeat-containing protein 70-like\tK24752 WDR70; WD repeat-containing protein 70" }, { "name":"120200652 LOW QUALITY PROTEIN: WD repeat-containing protein 76-like\tK24755 WDR76; WD repeat-containing protein 76" }, { "name":"120186395 abasic site processing protein YoqW-like isoform X1\tK28434 HMCES; abasic site processing protein HMCES" } ] } ] } ] }, { "name":"TLS (translesion DNA synthesis) factors", "children":[ { "name":"Y-family DNA polymerases", "children":[ { "name":"120217051 DNA polymerase eta\tK03509 POLH; DNA polymerase eta [EC:2.7.7.7]" }, { "name":"120173086 DNA polymerase kappa-like isoform X1\tK03511 POLK; DNA polymerase kappa [EC:2.7.7.7]" }, { "name":"120134674 DNA repair protein REV1 isoform X1\tK03515 REV1; DNA repair protein REV1 [EC:2.7.7.-]" } ] }, { "name":"B-family DNA polymerases", "children":[ { "name":"120192423 LOW QUALITY PROTEIN: DNA polymerase zeta catalytic subunit-like\tK02350 REV3L; DNA polymerase zeta [EC:2.7.7.7]" } ] }, { "name":"A-family DNA polymerase" }, { "name":"Rad6 epistasis group", "children":[ { "name":"120121985 ubiquitin-conjugating enzyme E2 2-like isoform X1\tK10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]" }, { "name":"120125141 ubiquitin-conjugating enzyme E2 2-like isoform X1\tK10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]" }, { "name":"120133642 ubiquitin-conjugating enzyme E2 2-like\tK10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]" }, { "name":"120156527 ubiquitin-conjugating enzyme E2 2-like isoform X1\tK10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]" }, { "name":"120158880 ubiquitin-conjugating enzyme E2 2 isoform X1\tK10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]" }, { "name":"120163070 ubiquitin-conjugating enzyme E2 2-like\tK10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]" }, { "name":"120163221 ubiquitin-conjugating enzyme E2 2-like\tK10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]" }, { "name":"120181140 ubiquitin-conjugating enzyme E2 2-like isoform X1\tK10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]" }, { "name":"120187326 ubiquitin-conjugating enzyme E2 2-like isoform X1\tK10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]" }, { "name":"120193336 ubiquitin-conjugating enzyme E2 2-like isoform X1\tK10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]" }, { "name":"120208589 ubiquitin-conjugating enzyme E2 2-like\tK10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]" }, { "name":"120216015 ubiquitin-conjugating enzyme E2 2-like isoform X1\tK10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]" }, { "name":"120151467 DNA repair protein RAD5B-like\tK15505 RAD5; DNA repair protein RAD5 [EC:5.6.2.-]" }, { "name":"120162422 DNA repair protein RAD5A isoform X1\tK15505 RAD5; DNA repair protein RAD5 [EC:5.6.2.-]" }, { "name":"120113832 LOW QUALITY PROTEIN: putative SWI\/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3-like 1\tK15711 SMARCA3; SWI\/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A3 [EC:5.6.2. 2.3.2.27]" }, { "name":"120113767 ubiquitin-conjugating enzyme E2 variant 1D isoform X1\tK10704 UBE2V; ubiquitin-conjugating enzyme E2 variant" }, { "name":"120116774 ubiquitin-conjugating enzyme E2 variant 1D-like\tK10704 UBE2V; ubiquitin-conjugating enzyme E2 variant" }, { "name":"120118045 ubiquitin-conjugating enzyme E2 variant 1A-like isoform X1\tK10704 UBE2V; ubiquitin-conjugating enzyme E2 variant" }, { "name":"120124763 ubiquitin-conjugating enzyme E2 variant 1A-like\tK10704 UBE2V; ubiquitin-conjugating enzyme E2 variant" }, { "name":"120124932 ubiquitin-conjugating enzyme E2 variant 1A-like\tK10704 UBE2V; ubiquitin-conjugating enzyme E2 variant" }, { "name":"120126082 ubiquitin-conjugating enzyme E2 variant 1C-like\tK10704 UBE2V; ubiquitin-conjugating enzyme E2 variant" }, { "name":"120128745 ubiquitin-conjugating enzyme E2 variant 1D\tK10704 UBE2V; ubiquitin-conjugating enzyme E2 variant" }, { "name":"120146159 ubiquitin-conjugating enzyme E2 variant 1D-like\tK10704 UBE2V; ubiquitin-conjugating enzyme E2 variant" }, { "name":"120146566 ubiquitin-conjugating enzyme E2 variant 1D-like\tK10704 UBE2V; ubiquitin-conjugating enzyme E2 variant" }, { "name":"120149129 ubiquitin-conjugating enzyme E2 variant 1A-like\tK10704 UBE2V; ubiquitin-conjugating enzyme E2 variant" }, { "name":"120161750 ubiquitin-conjugating enzyme E2 variant 1D-like\tK10704 UBE2V; ubiquitin-conjugating enzyme E2 variant" }, { "name":"120165682 ubiquitin-conjugating enzyme E2 variant 1D-like isoform X1\tK10704 UBE2V; ubiquitin-conjugating enzyme E2 variant" }, { "name":"120169995 ubiquitin-conjugating enzyme E2 variant 1A-like\tK10704 UBE2V; ubiquitin-conjugating enzyme E2 variant" }, { "name":"120178916 ubiquitin-conjugating enzyme E2 variant 1A-like\tK10704 UBE2V; ubiquitin-conjugating enzyme E2 variant" }, { "name":"120181698 ubiquitin-conjugating enzyme E2 variant 1D-like\tK10704 UBE2V; ubiquitin-conjugating enzyme E2 variant" }, { "name":"120197186 ubiquitin-conjugating enzyme E2 variant 1A-like\tK10704 UBE2V; ubiquitin-conjugating enzyme E2 variant" }, { "name":"120200831 ubiquitin-conjugating enzyme E2 variant 1D-like\tK10704 UBE2V; ubiquitin-conjugating enzyme E2 variant" }, { "name":"120211496 ubiquitin-conjugating enzyme E2 variant 1A-like\tK10704 UBE2V; ubiquitin-conjugating enzyme E2 variant" }, { "name":"120143971 ubiquitin-conjugating enzyme E2 36-like\tK10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]" }, { "name":"120154696 ubiquitin-conjugating enzyme E2 36-like\tK10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]" }, { "name":"120163432 ubiquitin-conjugating enzyme E2 35\tK10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]" }, { "name":"120163817 ubiquitin-conjugating enzyme E2 36-like\tK10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]" }, { "name":"120169210 ubiquitin-conjugating enzyme E2 36-like\tK10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]" }, { "name":"120178724 ubiquitin-conjugating enzyme E2 35\tK10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]" }, { "name":"120201133 ubiquitin-conjugating enzyme E2 36-like isoform X1\tK10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]" }, { "name":"120219445 ubiquitin-conjugating enzyme E2 35-like\tK10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]" } ] }, { "name":"Other TLS factors", "children":[ { "name":"120141994 proliferating cell nuclear antigen-like\tK04802 PCNA; proliferating cell nuclear antigen" }, { "name":"120142191 proliferating cell nuclear antigen-like\tK04802 PCNA; proliferating cell nuclear antigen" }, { "name":"120143105 proliferating cell nuclear antigen-like\tK04802 PCNA; proliferating cell nuclear antigen" }, { "name":"120158512 proliferating cell nuclear antigen-like\tK04802 PCNA; proliferating cell nuclear antigen" }, { "name":"120160021 proliferating cell nuclear antigen-like\tK04802 PCNA; proliferating cell nuclear antigen" }, { "name":"120161675 proliferating cell nuclear antigen-like\tK04802 PCNA; proliferating cell nuclear antigen" }, { "name":"120167898 proliferating cell nuclear antigen\tK04802 PCNA; proliferating cell nuclear antigen" }, { "name":"120169677 proliferating cell nuclear antigen-like\tK04802 PCNA; proliferating cell nuclear antigen" }, { "name":"120170420 proliferating cell nuclear antigen-like\tK04802 PCNA; proliferating cell nuclear antigen" }, { "name":"120171552 proliferating cell nuclear antigen-like\tK04802 PCNA; proliferating cell nuclear antigen" }, { "name":"120171821 proliferating cell nuclear antigen-like\tK04802 PCNA; proliferating cell nuclear antigen" }, { "name":"120194275 proliferating cell nuclear antigen 2-like\tK04802 PCNA; proliferating cell nuclear antigen" }, { "name":"120199312 proliferating cell nuclear antigen-like\tK04802 PCNA; proliferating cell nuclear antigen" } ] } ] }, { "name":"Check point factors", "children":[ { "name":"Rad9-Hus1-Rad1 complex", "children":[ { "name":"120154765 cell cycle checkpoint control protein RAD9A-like\tK10994 RAD9A; cell cycle checkpoint control protein RAD9A [EC:3.1.11.2]" }, { "name":"120167246 cell cycle checkpoint control protein RAD9A-like\tK10994 RAD9A; cell cycle checkpoint control protein RAD9A [EC:3.1.11.2]" }, { "name":"120119852 uncharacterized protein LOC120119852\tK10903 HUS1; HUS1 checkpoint protein" }, { "name":"120195810 uncharacterized protein LOC120195810\tK10903 HUS1; HUS1 checkpoint protein" }, { "name":"120199138 uncharacterized protein LOC120199138 isoform X1\tK02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]" } ] }, { "name":"HRAD17(Rad24)-RFC complex", "children":[ { "name":"120125400 cell cycle checkpoint protein RAD17\tK06662 HRAD17; cell cycle checkpoint protein" }, { "name":"120117412 replication factor C subunit 2\tK10755 RFC2_4; replication factor C subunit 2\/4" }, { "name":"120143126 replication factor C subunit 2-like isoform X1\tK10755 RFC2_4; replication factor C subunit 2\/4" }, { "name":"120169112 replication factor C subunit 4-like\tK10755 RFC2_4; replication factor C subunit 2\/4" }, { "name":"120181561 replication factor C subunit 4-like\tK10755 RFC2_4; replication factor C subunit 2\/4" }, { "name":"120199325 replication factor C subunit 2-like\tK10755 RFC2_4; replication factor C subunit 2\/4" }, { "name":"120121399 replication factor C subunit 3-like\tK10756 RFC3_5; replication factor C subunit 3\/5" }, { "name":"120123631 replication factor C subunit 3-like\tK10756 RFC3_5; replication factor C subunit 3\/5" }, { "name":"120129117 replication factor C subunit 3 isoform X1\tK10756 RFC3_5; replication factor C subunit 3\/5" }, { "name":"120130054 replication factor C subunit 3-like\tK10756 RFC3_5; replication factor C subunit 3\/5" }, { "name":"120141786 uncharacterized protein LOC120141786\tK10756 RFC3_5; replication factor C subunit 3\/5" }, { "name":"120153033 uncharacterized protein LOC120153033\tK10756 RFC3_5; replication factor C subunit 3\/5" }, { "name":"120154352 replication factor C subunit 5-like\tK10756 RFC3_5; replication factor C subunit 3\/5" }, { "name":"120163246 replication factor C subunit 3-like\tK10756 RFC3_5; replication factor C subunit 3\/5" }, { "name":"120180390 replication factor C subunit 5-like\tK10756 RFC3_5; replication factor C subunit 3\/5" }, { "name":"120183776 uncharacterized protein LOC120183776\tK10756 RFC3_5; replication factor C subunit 3\/5" }, { "name":"120195002 replication factor C subunit 3-like\tK10756 RFC3_5; replication factor C subunit 3\/5" }, { "name":"120200748 replication factor C subunit 3-like\tK10756 RFC3_5; replication factor C subunit 3\/5" } ] }, { "name":"Rad17-Mec3-Ddc1 complex", "children":[ { "name":"120199138 uncharacterized protein LOC120199138 isoform X1\tK02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]" } ] }, { "name":"FPC (fork protection complex)", "children":[ { "name":"120206437 protein timeless homolog\tK10997 TIMELESS; replication fork protection complex subunit TIMELESS\/Tof1\/Swi1" }, { "name":"120169634 TIMELESS-interacting protein-like isoform X1\tK10998 TIPIN; replication fork protection complex subunit TIPIN\/Csm3\/Swi3" }, { "name":"120178971 chromosome segregation in meiosis protein 3-like\tK10998 TIPIN; replication fork protection complex subunit TIPIN\/Csm3\/Swi3" }, { "name":"120210722 TIMELESS-interacting protein-like\tK10998 TIPIN; replication fork protection complex subunit TIPIN\/Csm3\/Swi3" } ] }, { "name":"Triple T complex", "children":[ { "name":"120148074 telomere length regulation protein TEL2 homolog\tK11137 TELO2; telomere length regulation protein" }, { "name":"120133796 uncharacterized protein LOC120133796\tK20403 TTI1; TELO2-interacting protein 1" }, { "name":"120119482 uncharacterized protein At2g39910-like\tK23115 TTI2; TELO2-interacting protein 2" }, { "name":"120151818 uncharacterized protein At2g39910-like\tK23115 TTI2; TELO2-interacting protein 2" }, { "name":"120196168 uncharacterized protein At2g39910-like\tK23115 TTI2; TELO2-interacting protein 2" }, { "name":"120204000 uncharacterized protein At2g39910-like\tK23115 TTI2; TELO2-interacting protein 2" } ] }, { "name":"BAG6-UBL4A-GET4 complex", "children":[ { "name":"120117597 ubiquitin-like domain-containing protein CIP73\tK23390 BAG6; large proline-rich protein BAG6" }, { "name":"120169379 ubiquitin-like domain-containing protein CIP73 isoform X1\tK23390 BAG6; large proline-rich protein BAG6" }, { "name":"120179408 ubiquitin-like domain-containing protein CIP73\tK23390 BAG6; large proline-rich protein BAG6" }, { "name":"120175753 Golgi to ER traffic protein 4 homolog isoform X1\tK23387 GET4; golgi to ER traffic protein 4" } ] }, { "name":"SOSS complex", "children":[ { "name":"120131942 integrator complex subunit 3 homolog\tK13140 INTS3; integrator complex subunit 3 (SOSS complex subunit A)" }, { "name":"120157119 LOW QUALITY PROTEIN: integrator complex subunit 3-like\tK13140 INTS3; integrator complex subunit 3 (SOSS complex subunit A)" }, { "name":"120127261 SOSS complex subunit B homolog\tK28889 NABP; SOSS complex subunit B" } ] }, { "name":"Other check point factors", "children":[ { "name":"120173574 serine\/threonine-protein kinase ATR\tK06640 ATR; serine\/threonine-protein kinase ATR [EC:2.7.11.1]" }, { "name":"120208213 LOW QUALITY PROTEIN: serine\/threonine-protein kinase ATR-like\tK06640 ATR; serine\/threonine-protein kinase ATR [EC:2.7.11.1]" }, { "name":"120204566 LOW QUALITY PROTEIN: serine\/threonine-protein kinase ATM-like\tK04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]" }, { "name":"120113916 14-3-3-like protein A\tK06630 YWHAE; 14-3-3 protein epsilon" }, { "name":"120118240 14-3-3-like protein GF14 iota\tK06630 YWHAE; 14-3-3 protein epsilon" }, { "name":"120120948 14-3-3-like protein\tK06630 YWHAE; 14-3-3 protein epsilon" }, { "name":"120121878 14-3-3-like protein D\tK06630 YWHAE; 14-3-3 protein epsilon" }, { "name":"120126250 14-3-3-like protein GF14 chi\tK06630 YWHAE; 14-3-3 protein epsilon" }, { "name":"120126308 14-3-3-like protein\tK06630 YWHAE; 14-3-3 protein epsilon" }, { "name":"120126860 14-3-3 protein 4-like\tK06630 YWHAE; 14-3-3 protein epsilon" }, { "name":"120126936 14-3-3-like protein A\tK06630 YWHAE; 14-3-3 protein epsilon" }, { "name":"120127977 14-3-3-like protein\tK06630 YWHAE; 14-3-3 protein epsilon" }, { "name":"120129390 14-3-3-like protein\tK06630 YWHAE; 14-3-3 protein epsilon" }, { "name":"120131054 14-3-3-like protein A\tK06630 YWHAE; 14-3-3 protein epsilon" }, { "name":"120131373 14-3-3-like protein D\tK06630 YWHAE; 14-3-3 protein epsilon" }, { "name":"120134503 14-3-3-like protein\tK06630 YWHAE; 14-3-3 protein epsilon" }, { "name":"120135271 14-3-3-like protein GF14 kappa\tK06630 YWHAE; 14-3-3 protein epsilon" }, { "name":"120145973 14-3-3-like protein\tK06630 YWHAE; 14-3-3 protein epsilon" }, { "name":"120147512 14-3-3-like protein\tK06630 YWHAE; 14-3-3 protein epsilon" }, { "name":"120151042 14-3-3 protein 6-like\tK06630 YWHAE; 14-3-3 protein epsilon" }, { "name":"120152413 14-3-3 protein 4\tK06630 YWHAE; 14-3-3 protein epsilon" }, { "name":"120154185 14-3-3-like protein A\tK06630 YWHAE; 14-3-3 protein epsilon" }, { "name":"120154471 14-3-3-like protein\tK06630 YWHAE; 14-3-3 protein epsilon" }, { "name":"120155643 14-3-3 protein 10-like\tK06630 YWHAE; 14-3-3 protein epsilon" }, { "name":"120155986 14-3-3-like protein B\tK06630 YWHAE; 14-3-3 protein epsilon" }, { "name":"120156422 14-3-3-like protein GF14 iota\tK06630 YWHAE; 14-3-3 protein epsilon" }, { "name":"120160702 14-3-3 protein 2-like\tK06630 YWHAE; 14-3-3 protein epsilon" }, { "name":"120160949 14-3-3-like protein\tK06630 YWHAE; 14-3-3 protein epsilon" }, { "name":"120161299 14-3-3-like protein A\tK06630 YWHAE; 14-3-3 protein epsilon" }, { "name":"120169028 14-3-3 protein 7-like\tK06630 YWHAE; 14-3-3 protein epsilon" }, { "name":"120170894 14-3-3-like protein GF14 iota\tK06630 YWHAE; 14-3-3 protein epsilon" }, { "name":"120171011 14-3-3-like protein A\tK06630 YWHAE; 14-3-3 protein epsilon" }, { "name":"120171676 14-3-3-like protein C\tK06630 YWHAE; 14-3-3 protein epsilon" }, { "name":"120173818 14-3-3 protein 6-like\tK06630 YWHAE; 14-3-3 protein epsilon" }, { "name":"120175379 14-3-3-like protein GF14 omega\tK06630 YWHAE; 14-3-3 protein epsilon" }, { "name":"120176335 14-3-3-like protein B\tK06630 YWHAE; 14-3-3 protein epsilon" }, { "name":"120176420 14-3-3-like protein\tK06630 YWHAE; 14-3-3 protein epsilon" }, { "name":"120178011 14-3-3 protein 6-like\tK06630 YWHAE; 14-3-3 protein epsilon" }, { "name":"120180132 14-3-3-like protein B\tK06630 YWHAE; 14-3-3 protein epsilon" }, { "name":"120180340 LOW QUALITY PROTEIN: 14-3-3-like protein\tK06630 YWHAE; 14-3-3 protein epsilon" }, { "name":"120180553 14-3-3-like protein\tK06630 YWHAE; 14-3-3 protein epsilon" }, { "name":"120182173 14-3-3 protein 7-like\tK06630 YWHAE; 14-3-3 protein epsilon" }, { "name":"120182917 14-3-3-like protein B\tK06630 YWHAE; 14-3-3 protein epsilon" }, { "name":"120188355 14-3-3 protein 6-like\tK06630 YWHAE; 14-3-3 protein epsilon" }, { "name":"120191072 14-3-3-like protein\tK06630 YWHAE; 14-3-3 protein epsilon" }, { "name":"120191084 14-3-3 protein 7\tK06630 YWHAE; 14-3-3 protein epsilon" }, { "name":"120191320 14-3-3-like protein B\tK06630 YWHAE; 14-3-3 protein epsilon" }, { "name":"120193791 14-3-3-like protein B\tK06630 YWHAE; 14-3-3 protein epsilon" }, { "name":"120194818 14-3-3 protein 8-like\tK06630 YWHAE; 14-3-3 protein epsilon" }, { "name":"120194874 14-3-3 protein 7-like\tK06630 YWHAE; 14-3-3 protein epsilon" }, { "name":"120195097 14-3-3-like protein\tK06630 YWHAE; 14-3-3 protein epsilon" }, { "name":"120195647 14-3-3 protein 7-like\tK06630 YWHAE; 14-3-3 protein epsilon" }, { "name":"120197903 14-3-3-like protein GF14 kappa\tK06630 YWHAE; 14-3-3 protein epsilon" }, { "name":"120198030 14-3-3 protein 7-like isoform X1\tK06630 YWHAE; 14-3-3 protein epsilon" }, { "name":"120198192 14-3-3-like protein\tK06630 YWHAE; 14-3-3 protein epsilon" }, { "name":"120207669 14-3-3 protein 6-like\tK06630 YWHAE; 14-3-3 protein epsilon" }, { "name":"120211142 14-3-3-like protein GF14 iota\tK06630 YWHAE; 14-3-3 protein epsilon" }, { "name":"120214935 14-3-3-like protein\tK06630 YWHAE; 14-3-3 protein epsilon" }, { "name":"120218601 14-3-3-like protein B\tK06630 YWHAE; 14-3-3 protein epsilon" }, { "name":"120143747 LOW QUALITY PROTEIN: wee1-like protein kinase\tK06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]" }, { "name":"120115709 LOW QUALITY PROTEIN: uncharacterized protein LOC120115709\tK20780 MDC1; mediator of DNA damage checkpoint protein 1" }, { "name":"120164084 uncharacterized protein LOC120164084 isoform X1\tK20780 MDC1; mediator of DNA damage checkpoint protein 1" }, { "name":"120201214 uncharacterized protein LOC120201214 isoform X1\tK20780 MDC1; mediator of DNA damage checkpoint protein 1" }, { "name":"120115277 serine\/threonine-protein kinase Nek5-like isoform X1\tK08857 NEK1_4_5; serine\/threonine-protein kinase Nek1\/4\/5 [EC:2.7.11.1]" }, { "name":"120117751 serine\/threonine-protein kinase Nek2-like isoform X1\tK08857 NEK1_4_5; serine\/threonine-protein kinase Nek1\/4\/5 [EC:2.7.11.1]" }, { "name":"120124662 serine\/threonine-protein kinase Nek2-like\tK08857 NEK1_4_5; serine\/threonine-protein kinase Nek1\/4\/5 [EC:2.7.11.1]" }, { "name":"120126771 serine\/threonine-protein kinase Nek4-like\tK08857 NEK1_4_5; serine\/threonine-protein kinase Nek1\/4\/5 [EC:2.7.11.1]" }, { "name":"120132178 serine\/threonine-protein kinase Nek5-like isoform X1\tK08857 NEK1_4_5; serine\/threonine-protein kinase Nek1\/4\/5 [EC:2.7.11.1]" }, { "name":"120136617 serine\/threonine-protein kinase Nek6-like\tK08857 NEK1_4_5; serine\/threonine-protein kinase Nek1\/4\/5 [EC:2.7.11.1]" }, { "name":"120138888 serine\/threonine-protein kinase Nek2-like\tK08857 NEK1_4_5; serine\/threonine-protein kinase Nek1\/4\/5 [EC:2.7.11.1]" }, { "name":"120142402 serine\/threonine-protein kinase Nek6-like\tK08857 NEK1_4_5; serine\/threonine-protein kinase Nek1\/4\/5 [EC:2.7.11.1]" }, { "name":"120144188 serine\/threonine-protein kinase Nek5-like\tK08857 NEK1_4_5; serine\/threonine-protein kinase Nek1\/4\/5 [EC:2.7.11.1]" }, { "name":"120146545 serine\/threonine-protein kinase Nek6-like\tK08857 NEK1_4_5; serine\/threonine-protein kinase Nek1\/4\/5 [EC:2.7.11.1]" }, { "name":"120154816 serine\/threonine-protein kinase Nek2-like\tK08857 NEK1_4_5; serine\/threonine-protein kinase Nek1\/4\/5 [EC:2.7.11.1]" }, { "name":"120155531 serine\/threonine-protein kinase Nek5-like\tK08857 NEK1_4_5; serine\/threonine-protein kinase Nek1\/4\/5 [EC:2.7.11.1]" }, { "name":"120155635 serine\/threonine-protein kinase Nek6-like\tK08857 NEK1_4_5; serine\/threonine-protein kinase Nek1\/4\/5 [EC:2.7.11.1]" }, { "name":"120157177 serine\/threonine-protein kinase Nek5-like\tK08857 NEK1_4_5; serine\/threonine-protein kinase Nek1\/4\/5 [EC:2.7.11.1]" }, { "name":"120162105 serine\/threonine-protein kinase Nek2-like\tK08857 NEK1_4_5; serine\/threonine-protein kinase Nek1\/4\/5 [EC:2.7.11.1]" }, { "name":"120177346 serine\/threonine-protein kinase Nek1-like\tK08857 NEK1_4_5; serine\/threonine-protein kinase Nek1\/4\/5 [EC:2.7.11.1]" }, { "name":"120185224 serine\/threonine-protein kinase Nek1-like\tK08857 NEK1_4_5; serine\/threonine-protein kinase Nek1\/4\/5 [EC:2.7.11.1]" }, { "name":"120188517 serine\/threonine-protein kinase Nek2-like\tK08857 NEK1_4_5; serine\/threonine-protein kinase Nek1\/4\/5 [EC:2.7.11.1]" }, { "name":"120189851 serine\/threonine-protein kinase Nek2-like\tK08857 NEK1_4_5; serine\/threonine-protein kinase Nek1\/4\/5 [EC:2.7.11.1]" }, { "name":"120194253 serine\/threonine-protein kinase Nek5-like\tK08857 NEK1_4_5; serine\/threonine-protein kinase Nek1\/4\/5 [EC:2.7.11.1]" }, { "name":"120202037 serine\/threonine-protein kinase Nek6-like\tK08857 NEK1_4_5; serine\/threonine-protein kinase Nek1\/4\/5 [EC:2.7.11.1]" }, { "name":"120209688 serine\/threonine-protein kinase Nek2-like\tK08857 NEK1_4_5; serine\/threonine-protein kinase Nek1\/4\/5 [EC:2.7.11.1]" }, { "name":"120213288 serine\/threonine-protein kinase Nek2-like\tK08857 NEK1_4_5; serine\/threonine-protein kinase Nek1\/4\/5 [EC:2.7.11.1]" }, { "name":"120216913 serine\/threonine-protein kinase Nek6-like\tK08857 NEK1_4_5; serine\/threonine-protein kinase Nek1\/4\/5 [EC:2.7.11.1]" }, { "name":"120155176 protein downstream neighbor of son homolog isoform X1\tK22422 DONSON; protein downstream neighbor of Son" }, { "name":"120177777 LOW QUALITY PROTEIN: protein downstream neighbor of Son-like\tK22422 DONSON; protein downstream neighbor of Son" }, { "name":"120200813 protein downstream neighbor of Son-like isoform X1\tK22422 DONSON; protein downstream neighbor of Son" }, { "name":"120214577 uncharacterized protein LOC120214577\tK22422 DONSON; protein downstream neighbor of Son" }, { "name":"120217097 protein downstream neighbor of Son-like\tK22422 DONSON; protein downstream neighbor of Son" }, { "name":"120142253 protein SUPPRESSOR OF K(+) TRANSPORT GROWTH DEFECT 1-like\tK12196 VPS4; vacuolar protein-sorting-associated protein 4" }, { "name":"120150425 protein SUPPRESSOR OF K(+) TRANSPORT GROWTH DEFECT 1-like\tK12196 VPS4; vacuolar protein-sorting-associated protein 4" }, { "name":"120159921 protein SUPPRESSOR OF K(+) TRANSPORT GROWTH DEFECT 1\tK12196 VPS4; vacuolar protein-sorting-associated protein 4" }, { "name":"120194392 protein SUPPRESSOR OF K(+) TRANSPORT GROWTH DEFECT 1-like\tK12196 VPS4; vacuolar protein-sorting-associated protein 4" }, { "name":"120211958 protein SUPPRESSOR OF K(+) TRANSPORT GROWTH DEFECT 1-like\tK12196 VPS4; vacuolar protein-sorting-associated protein 4" }, { "name":"120121146 replication stress response regulator SDE2-like\tK25059 SDE2; replication stress response regulator SDE2" }, { "name":"120161371 replication stress response regulator SDE2-like\tK25059 SDE2; replication stress response regulator SDE2" }, { "name":"120182788 replication stress response regulator SDE2-like\tK25059 SDE2; replication stress response regulator SDE2" }, { "name":"120200541 replication stress response regulator SDE2-like\tK25059 SDE2; replication stress response regulator SDE2" }, { "name":"120148797 LOW QUALITY PROTEIN: protein DECREASED SIZE EXCLUSION LIMIT 1-like\tK24770 DSE1; protein decreased size exclusion limit 1" }, { "name":"120185401 protein DECREASED SIZE EXCLUSION LIMIT 1-like\tK24770 DSE1; protein decreased size exclusion limit 1" } ] } ] }, { "name":"Other factors with a suspected DNA repair function", "children":[ { "name":"DNA polymerases", "children":[ { "name":"120161631 helicase and polymerase-containing protein TEBICHI isoform X1\tK02349 POLQ; DNA polymerase theta [EC:2.7.7.7]" }, { "name":"120149815 LOW QUALITY PROTEIN: myb-binding protein 1A-like protein\tK02331 POL5; DNA polymerase phi [EC:2.7.7.7]" }, { "name":"120178872 myb-binding protein 1A-like protein\tK02331 POL5; DNA polymerase phi [EC:2.7.7.7]" }, { "name":"120202219 LOW QUALITY PROTEIN: myb-binding protein 1A-like protein\tK02331 POL5; DNA polymerase phi [EC:2.7.7.7]" }, { "name":"120158425 LOW QUALITY PROTEIN: DNA-directed primase\/polymerase protein\tK22761 PRIMPOL; DNA-directed primase\/polymerase protein [EC:2.7.7.102 2.7.7.7]" } ] }, { "name":"Nucleases", "children":[ { "name":"120147596 DNA cross-link repair 1A protein-like\tK15340 DCLRE1A; DNA cross-link repair 1A protein" }, { "name":"120184616 protein artemis-like\tK15340 DCLRE1A; DNA cross-link repair 1A protein" }, { "name":"120168361 5' exonuclease Apollo\tK15341 DCLRE1B; DNA cross-link repair 1B protein [EC:3.1.-.-]" }, { "name":"120211549 exonuclease V, chloroplastic\tK17815 EXO5; exonuclease V [EC:3.1.-.-]" }, { "name":"120194421 endonuclease V-like\tK21813 ENDOV; endonuclease V [EC:3.1.26.-]" }, { "name":"120211003 endonuclease V-like isoform X1\tK21813 ENDOV; endonuclease V [EC:3.1.26.-]" }, { "name":"120126070 endonuclease 4-like\tK05986 NUCS; nuclease S1 [EC:3.1.30.1]" }, { "name":"120127712 endonuclease 1-like isoform X1\tK05986 NUCS; nuclease S1 [EC:3.1.30.1]" }, { "name":"120170792 endonuclease 1-like\tK05986 NUCS; nuclease S1 [EC:3.1.30.1]" }, { "name":"120184753 endonuclease 2-like\tK05986 NUCS; nuclease S1 [EC:3.1.30.1]" }, { "name":"120194626 endonuclease 4-like\tK05986 NUCS; nuclease S1 [EC:3.1.30.1]" }, { "name":"120209224 endonuclease 2-like\tK05986 NUCS; nuclease S1 [EC:3.1.30.1]" } ] }, { "name":"Helicases", "children":[ { "name":"120205572 switch 2\tK20098 ERCC6L2; DNA excision repair protein ERCC-6-like 2 [EC:5.6.2.-]" }, { "name":"120216119 switch 2-like\tK20098 ERCC6L2; DNA excision repair protein ERCC-6-like 2 [EC:5.6.2.-]" } ] }, { "name":"PSO4 complex", "children":[ { "name":"120134922 pre-mRNA-processing factor 19 homolog 1-like isoform X1\tK10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]" }, { "name":"120164052 pre-mRNA-processing factor 19 homolog 1-like isoform X1\tK10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]" }, { "name":"120164943 cell division cycle 5-like protein\tK12860 CDC5L; pre-mRNA-splicing factor CDC5\/CEF1" }, { "name":"120208946 cell division cycle 5-like protein\tK12860 CDC5L; pre-mRNA-splicing factor CDC5\/CEF1" }, { "name":"120195796 pre-mRNA-splicing factor SPF27 homolog\tK12861 BCAS2; pre-mRNA-splicing factor SPF27" }, { "name":"120203967 pre-mRNA-splicing factor SPF27 homolog\tK12861 BCAS2; pre-mRNA-splicing factor SPF27" }, { "name":"120158249 protein pleiotropic regulatory locus 1-like\tK12862 PLRG1; pleiotropic regulator 1" }, { "name":"120178490 protein pleiotropic regulatory locus 1-like\tK12862 PLRG1; pleiotropic regulator 1" }, { "name":"120201229 protein pleiotropic regulatory locus 1-like\tK12862 PLRG1; pleiotropic regulator 1" } ] }, { "name":"Modulation of nucleotide pools", "children":[ { "name":"120197271 LOW QUALITY PROTEIN: geranyl diphosphate phosphohydrolase\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]" }, { "name":"120120432 deoxyuridine 5'-triphosphate nucleotidohydrolase-like\tK01520 dut; dUTP diphosphatase [EC:3.6.1.23]" }, { "name":"120144922 deoxyuridine 5'-triphosphate nucleotidohydrolase-like\tK01520 dut; dUTP diphosphatase [EC:3.6.1.23]" }, { "name":"120159100 deoxyuridine 5'-triphosphate nucleotidohydrolase-like\tK01520 dut; dUTP diphosphatase [EC:3.6.1.23]" }, { "name":"120167510 deoxyuridine 5'-triphosphate nucleotidohydrolase-like\tK01520 dut; dUTP diphosphatase [EC:3.6.1.23]" }, { "name":"120168218 LOW QUALITY PROTEIN: deoxyuridine 5'-triphosphate nucleotidohydrolase-like\tK01520 dut; dUTP diphosphatase [EC:3.6.1.23]" }, { "name":"120179186 deoxyuridine 5'-triphosphate nucleotidohydrolase-like\tK01520 dut; dUTP diphosphatase [EC:3.6.1.23]" }, { "name":"120163530 ribonucleoside-diphosphate reductase large subunit-like\tK10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]" }, { "name":"120174400 ribonucleoside-diphosphate reductase large subunit\tK10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]" }, { "name":"120184586 ribonucleoside-diphosphate reductase large subunit-like\tK10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]" }, { "name":"120114370 ribonucleoside-diphosphate reductase small chain A-like\tK10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]" }, { "name":"120128440 ribonucleoside-diphosphate reductase small chain A-like isoform X1\tK10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]" }, { "name":"120159456 ribonucleoside-diphosphate reductase small chain-like\tK10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]" }, { "name":"120169996 ribonucleoside-diphosphate reductase small chain\tK10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]" }, { "name":"120185610 ribonucleoside-diphosphate reductase small chain-like\tK10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]" }, { "name":"120212511 ribonucleoside-diphosphate reductase small chain-like\tK10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]" } ] } ] } ] }, { "name":"Prokaryotic type", "children":[ { "name":"SSBR (single strand breaks repair)", "children":[ { "name":"Direct repair", "children":[ { "name":"120158718 LOW QUALITY PROTEIN: deoxyribodipyrimidine photo-lyase-like\tK01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]" } ] }, { "name":"BER (base exicision repair)", "children":[ { "name":"DNA glycosylases", "children":[ { "name":"120187493 uracil-DNA glycosylase, mitochondrial\tK03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]" }, { "name":"120203817 uracil-DNA glycosylase, mitochondrial-like\tK03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]" }, { "name":"120167588 probable DNA-3-methyladenine glycosylase 2\tK01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]" }, { "name":"120168246 probable DNA-3-methyladenine glycosylase 2\tK01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]" }, { "name":"120194189 uncharacterized protein LOC120194189\tK01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]" }, { "name":"120216672 probable DNA-3-methyladenine glycosylase 2\tK01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]" }, { "name":"120169503 DNA-3-methyladenine glycosylase\tK03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]" }, { "name":"120114027 adenine DNA glycosylase-like\tK03575 mutY; A\/G-specific adenine glycosylase [EC:3.2.2.31]" }, { "name":"120121087 adenine DNA glycosylase-like\tK03575 mutY; A\/G-specific adenine glycosylase [EC:3.2.2.31]" }, { "name":"120117065 LOW QUALITY PROTEIN: DNA-3-methyladenine glycosylase 1-like\tK01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]" }, { "name":"120130315 uncharacterized protein LOC120130315\tK01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]" }, { "name":"120132228 probable GMP synthase [glutamine-hydrolyzing]\tK01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]" }, { "name":"120141363 probable GMP synthase [glutamine-hydrolyzing]\tK01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]" }, { "name":"120145449 uncharacterized protein LOC120145449 isoform X1\tK01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]" }, { "name":"120147945 probable GMP synthase [glutamine-hydrolyzing]\tK01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]" }, { "name":"120150086 probable GMP synthase [glutamine-hydrolyzing]\tK01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]" }, { "name":"120157365 uncharacterized protein LOC120157365\tK01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]" }, { "name":"120161445 probable GMP synthase [glutamine-hydrolyzing]\tK01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]" }, { "name":"120183691 DNA-3-methyladenine glycosylase 1-like\tK01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]" }, { "name":"120187586 DNA-3-methyladenine glycosylase-like\tK01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]" }, { "name":"120192579 probable GMP synthase [glutamine-hydrolyzing]\tK01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]" }, { "name":"120194211 probable GMP synthase [glutamine-hydrolyzing] isoform X1\tK01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]" }, { "name":"120194554 probable GMP synthase [glutamine-hydrolyzing]\tK01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]" }, { "name":"120197447 DNA-3-methyladenine glycosylase-like\tK01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]" }, { "name":"120197973 uncharacterized protein LOC120197973\tK01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]" }, { "name":"120125431 formamidopyrimidine-DNA glycosylase-like isoform X1\tK10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]" }, { "name":"120185814 formamidopyrimidine-DNA glycosylase isoform X1\tK10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]" }, { "name":"120139664 endonuclease III homolog 1, chloroplastic\tK10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]" } ] }, { "name":"AP endonucleases", "children":[ { "name":"120116914 DNA-(apurinic or apyrimidinic site) endonuclease, chloroplastic-like isoform X1\tK01142 xthA; exodeoxyribonuclease III [EC:3.1.11.2]" }, { "name":"120214591 DNA-(apurinic or apyrimidinic site) endonuclease, chloroplastic-like\tK01142 xthA; exodeoxyribonuclease III [EC:3.1.11.2]" } ] }, { "name":"RecJ" }, { "name":"DNA ligase" }, { "name":"DNA polymerase I", "children":[ { "name":"120160446 DNA polymerase I A, chloroplastic\/mitochondrial-like\tK02335 polA; DNA polymerase I [EC:2.7.7.7]" }, { "name":"120198424 DNA polymerase I A, chloroplastic\/mitochondrial-like\tK02335 polA; DNA polymerase I [EC:2.7.7.7]" } ] } ] }, { "name":"NER (nucleotide excision repair)", "children":[ { "name":"GGR (global genome repair) factors", "children":[ { "name":"120160446 DNA polymerase I A, chloroplastic\/mitochondrial-like\tK02335 polA; DNA polymerase I [EC:2.7.7.7]" }, { "name":"120198424 DNA polymerase I A, chloroplastic\/mitochondrial-like\tK02335 polA; DNA polymerase I [EC:2.7.7.7]" } ] }, { "name":"TCR (transcription coupled repair) factors", "children":[ { "name":"DNA-directed RNA polymerase complex (RNAP)", "children":[ { "name":"24143698 rpoB; RNA polymerase beta subunit\tK03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]" }, { "name":"120185727 DNA-directed RNA polymerase subunit beta'-like\tK03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]" }, { "name":"24143696 rpoC2; RNA polymerase beta' subunit\tK03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]" }, { "name":"24143697 rpoC1; RNA polymerase beta' subunit\tK03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]" }, { "name":"24143737 rpoA; RNA polymerase alpha subunit\tK03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]" } ] }, { "name":"TRCF (transcription-repair coupling factor)" } ] } ] }, { "name":"MMR (mismatch excision repair)", "children":[ { "name":"Mismatch and loop recognition factors", "children":[ { "name":"120210502 LOW QUALITY PROTEIN: endonuclease MutS2-like\tK07456 mutS2; DNA mismatch repair protein MutS2" } ] }, { "name":"Molecular matchmaker" }, { "name":"Strand discrimination factor" }, { "name":"DNA exonucleases" }, { "name":"DNA polymerase III holoenzyme" }, { "name":"DNA ligase" }, { "name":"Other MMR factors", "children":[ { "name":"120139924 single-stranded DNA-binding protein, mitochondrial-like\tK03111 ssb; single-strand DNA-binding protein" }, { "name":"120207808 single-stranded DNA-binding protein, mitochondrial-like\tK03111 ssb; single-strand DNA-binding protein" }, { "name":"120207883 single-stranded DNA-binding protein, mitochondrial\tK03111 ssb; single-strand DNA-binding protein" } ] } ] } ] }, { "name":"DSBR (double strand breaks repair)", "children":[ { "name":"HR (homologous recombination)", "children":[ { "name":"RecBC pathway proteins", "children":[ { "name":"120117630 DNA repair protein recA homolog 3, mitochondrial-like isoform X1\tK03553 recA; recombination protein RecA" }, { "name":"120127900 LOW QUALITY PROTEIN: DNA repair protein recA homolog 1, chloroplastic-like\tK03553 recA; recombination protein RecA" }, { "name":"120169303 DNA repair protein recA homolog 3, mitochondrial-like isoform X1\tK03553 recA; recombination protein RecA" }, { "name":"120201331 DNA repair protein recA homolog 3, mitochondrial-like\tK03553 recA; recombination protein RecA" } ] }, { "name":"RecFOR pathway proteins", "children":[ { "name":"120117630 DNA repair protein recA homolog 3, mitochondrial-like isoform X1\tK03553 recA; recombination protein RecA" }, { "name":"120127900 LOW QUALITY PROTEIN: DNA repair protein recA homolog 1, chloroplastic-like\tK03553 recA; recombination protein RecA" }, { "name":"120169303 DNA repair protein recA homolog 3, mitochondrial-like isoform X1\tK03553 recA; recombination protein RecA" }, { "name":"120201331 DNA repair protein recA homolog 3, mitochondrial-like\tK03553 recA; recombination protein RecA" }, { "name":"120159428 DNA repair protein RadA-like\tK04485 radA; DNA repair protein RadA\/Sms" }, { "name":"120210828 ATP-dependent DNA helicase homolog RECG, chloroplastic-like isoform X1\tK03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]" } ] }, { "name":"AddAB pathway proteins" }, { "name":"Other HR factor" }, { "name":"Archaeal homologous recombinant proteins" } ] }, { "name":"NHEJ (non-homologous end-joining)", "children":[ { "name":"Two-component NHEJ DNA repair complex" }, { "name":"SHIIR (short-homology-independent illegitimate recombination)", "children":[ { "name":"Facilitator", "children":[ { "name":"120120062 LOW QUALITY PROTEIN: DNA gyrase subunit A, chloroplastic\/mitochondrial-like\tK02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]" }, { "name":"120200024 DNA gyrase subunit A, chloroplastic\/mitochondrial\tK02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]" }, { "name":"120143041 LOW QUALITY PROTEIN: DNA gyrase subunit B, chloroplastic\/mitochondrial-like\tK02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]" }, { "name":"120188058 DNA gyrase subunit B, chloroplastic\/mitochondrial-like\tK02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]" } ] }, { "name":"Supressor" } ] }, { "name":"SHDIR (short-homology-dependent illegitimate recombination)", "children":[ { "name":"RecET pathway" }, { "name":"Facilitator" }, { "name":"Supressor" } ] } ] } ] }, { "name":"TLS (translesion DNA synthesis) factors", "children":[ { "name":"Y-family DNA polymerases" }, { "name":"Other SOS response factors", "children":[ { "name":"120117630 DNA repair protein recA homolog 3, mitochondrial-like isoform X1\tK03553 recA; recombination protein RecA" }, { "name":"120127900 LOW QUALITY PROTEIN: DNA repair protein recA homolog 1, chloroplastic-like\tK03553 recA; recombination protein RecA" }, { "name":"120169303 DNA repair protein recA homolog 3, mitochondrial-like isoform X1\tK03553 recA; recombination protein RecA" }, { "name":"120201331 DNA repair protein recA homolog 3, mitochondrial-like\tK03553 recA; recombination protein RecA" }, { "name":"120139924 single-stranded DNA-binding protein, mitochondrial-like\tK03111 ssb; single-strand DNA-binding protein" }, { "name":"120207808 single-stranded DNA-binding protein, mitochondrial-like\tK03111 ssb; single-strand DNA-binding protein" }, { "name":"120207883 single-stranded DNA-binding protein, mitochondrial\tK03111 ssb; single-strand DNA-binding protein" } ] } ] }, { "name":"Other factors with a suspected DNA repair function", "children":[ { "name":"DNA polymerase" }, { "name":"DNA helicases" }, { "name":"Modulation of nucleotide pools", "children":[ { "name":"120197271 LOW QUALITY PROTEIN: geranyl diphosphate phosphohydrolase\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]" }, { "name":"120120432 deoxyuridine 5'-triphosphate nucleotidohydrolase-like\tK01520 dut; dUTP diphosphatase [EC:3.6.1.23]" }, { "name":"120144922 deoxyuridine 5'-triphosphate nucleotidohydrolase-like\tK01520 dut; dUTP diphosphatase [EC:3.6.1.23]" }, { "name":"120159100 deoxyuridine 5'-triphosphate nucleotidohydrolase-like\tK01520 dut; dUTP diphosphatase [EC:3.6.1.23]" }, { "name":"120167510 deoxyuridine 5'-triphosphate nucleotidohydrolase-like\tK01520 dut; dUTP diphosphatase [EC:3.6.1.23]" }, { "name":"120168218 LOW QUALITY PROTEIN: deoxyuridine 5'-triphosphate nucleotidohydrolase-like\tK01520 dut; dUTP diphosphatase [EC:3.6.1.23]" }, { "name":"120179186 deoxyuridine 5'-triphosphate nucleotidohydrolase-like\tK01520 dut; dUTP diphosphatase [EC:3.6.1.23]" } ] }, { "name":"Others" } ] } ] } ] }