{
	"name":"isc03051",
	"children":[
	{
		"name":"Eukaryotic proteasome",
		"children":[
		{
			"name":"Core particles (20S proteasome)",
			"children":[
			{
				"name":"alpha type subunits",
				"children":[
				{
					"name":"8036174 proteasome subunit alpha type-6\tK02730 PSMA6; 20S proteasome subunit alpha 1 [EC:3.4.25.1]"
				},
				{
					"name":"8033547 proteasome subunit alpha type-2\tK02726 PSMA2; 20S proteasome subunit alpha 2 [EC:3.4.25.1]"
				},
				{
					"name":"115309468 proteasome subunit alpha type-4\tK02728 PSMA4; 20S proteasome subunit alpha 3 [EC:3.4.25.1]"
				},
				{
					"name":"8030720 proteasome subunit alpha type-7\tK02731 PSMA7; 20S proteasome subunit alpha 4 [EC:3.4.25.1]"
				},
				{
					"name":"115314718 proteasome subunit alpha type-5\tK02729 PSMA5; 20S proteasome subunit alpha 5 [EC:3.4.25.1]"
				},
				{
					"name":"115320943 proteasome subunit alpha type-1\tK02725 PSMA1; 20S proteasome subunit alpha 6 [EC:3.4.25.1]"
				},
				{
					"name":"8053959 proteasome subunit alpha type-3\tK02727 PSMA3; 20S proteasome subunit alpha 7 [EC:3.4.25.1]"
				}
				]
			},
			{
				"name":"beta type subunits",
				"children":[
				{
					"name":"8050668 proteasome subunit beta type-7\tK02739 PSMB7; 20S proteasome subunit beta 2 [EC:3.4.25.1]"
				},
				{
					"name":"8031644 proteasome subunit beta type-3\tK02735 PSMB3; 20S proteasome subunit beta 3 [EC:3.4.25.1]"
				},
				{
					"name":"8031393 proteasome subunit beta type-2\tK02734 PSMB2; 20S proteasome subunit beta 4 [EC:3.4.25.1]"
				},
				{
					"name":"115322038 proteasome subunit beta type-5\tK02737 PSMB5; 20S proteasome subunit beta 5 [EC:3.4.25.1]"
				},
				{
					"name":"115325462 proteasome subunit beta type-1\tK02732 PSMB1; 20S proteasome subunit beta 6 [EC:3.4.25.1]"
				}
				]
			}
			]
		},
		{
			"name":"Regulatory particles",
			"children":[
			{
				"name":"PA700 (19S proteasome)",
				"children":[
				{
					"name":"ATPase subunits",
					"children":[
					{
						"name":"115315567 26S proteasome regulatory subunit 7\tK03061 PSMC2; 26S proteasome regulatory subunit T1"
					},
					{
						"name":"8029023 26S proteasome regulatory subunit 4\tK03062 PSMC1; 26S proteasome regulatory subunit T2"
					},
					{
						"name":"8035919 26S proteasome regulatory subunit 6B\tK03063 PSMC4; 26S proteasome regulatory subunit T3"
					},
					{
						"name":"115314997 26S proteasome regulatory subunit 10B\tK03064 PSMC6; 26S proteasome regulatory subunit T4"
					},
					{
						"name":"115328623 26S proteasome regulatory subunit 6A-B\tK03065 PSMC3; 26S proteasome regulatory subunit T5"
					},
					{
						"name":"8035113 26S proteasome regulatory subunit 8 isoform X2\tK03066 PSMC5; 26S proteasome regulatory subunit T6"
					}
					]
				},
				{
					"name":"non-ATPase subunits",
					"children":[
					{
						"name":"8035556 26S proteasome non-ATPase regulatory subunit 2\tK03028 PSMD2; 26S proteasome regulatory subunit N1"
					},
					{
						"name":"115330545 LOW QUALITY PROTEIN: 26S proteasome non-ATPase regulatory subunit 1\tK03032 PSMD1; 26S proteasome regulatory subunit N2"
					},
					{
						"name":"8050626 26S proteasome non-ATPase regulatory subunit 3\tK03033 PSMD3; 26S proteasome regulatory subunit N3"
					},
					{
						"name":"8026740 26S proteasome non-ATPase regulatory subunit 12\tK03035 PSMD12; 26S proteasome regulatory subunit N5"
					},
					{
						"name":"120839185 26S proteasome non-ATPase regulatory subunit 11\tK03036 PSMD11; 26S proteasome regulatory subunit N6"
					},
					{
						"name":"8032705 26S proteasome non-ATPase regulatory subunit 6\tK03037 PSMD6; 26S proteasome regulatory subunit N7"
					},
					{
						"name":"8039108 26S proteasome non-ATPase regulatory subunit 7\tK03038 PSMD7; 26S proteasome regulatory subunit N8"
					},
					{
						"name":"8028252 26S proteasome non-ATPase regulatory subunit 14\tK03030 PSMD14; 26S proteasome regulatory subunit N11"
					},
					{
						"name":"115314998 26S proteasome non-ATPase regulatory subunit 8\tK03031 PSMD8; 26S proteasome regulatory subunit N12"
					},
					{
						"name":"8042785 26S proteasome complex subunit SEM1\tK10881 SHFM1; 26 proteasome complex subunit DSS1"
					}
					]
				}
				]
			},
			{
				"name":"PA28 (11S REG)",
				"children":[
				{
					"name":"8035330 proteasome activator complex subunit 3 isoform X1\tK06698 PSME3; proteasome activator subunit 3 (PA28 gamma)"
				}
				]
			},
			{
				"name":"PA200"
			},
			{
				"name":"PI31"
			}
			]
		},
		{
			"name":"Assembling factors",
			"children":[
			{
				"name":"Assembling chaperones",
				"children":[
				{
					"name":"8024479 proteasome assembly chaperone 2\tK11876 PSMG2; proteasome assembly chaperone 2"
				}
				]
			},
			{
				"name":"Other assembling factors",
				"children":[
				{
					"name":"115312539 heat shock protein 68-like\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
				},
				{
					"name":"115312541 heat shock protein 68-like\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
				},
				{
					"name":"115321088 heat shock protein 68-like\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
				},
				{
					"name":"115323617 heat shock protein 68-like\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
				},
				{
					"name":"115323629 heat shock protein 68-like\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
				},
				{
					"name":"115323694 heat shock protein 68\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
				},
				{
					"name":"121835372 heat shock protein 68-like\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
				},
				{
					"name":"8024675 heat shock protein 68-like\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
				},
				{
					"name":"8027107 heat shock 70 kDa protein cognate 4\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
				},
				{
					"name":"8033225 heat shock protein 68-like\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
				},
				{
					"name":"8037153 heat shock protein 70 B2\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
				},
				{
					"name":"8042924 heat shock protein 68-like\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
				},
				{
					"name":"8043999 heat shock protein 68\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
				},
				{
					"name":"8041558 heat shock protein HSP 90-alpha\tK04079 HSP90A; molecular chaperone HtpG"
				},
				{
					"name":"8041518 RNA-binding protein pno1 isoform X1\tK11884 PNO1; RNA-binding protein PNO1"
				}
				]
			}
			]
		},
		{
			"name":"Proteasome interacting proteins (PIPs)",
			"children":[
			{
				"name":"UBL-UBA shuttle proteins",
				"children":[
				{
					"name":"8030156 NEDD8 ultimate buster 1 isoform X1\tK29014 NUB1; NEDD8 ultimate buster 1"
				}
				]
			},
			{
				"name":"Other PIPs",
				"children":[
				{
					"name":"8025119 JNK1\/MAPK8-associated membrane protein\tK28966 JKAMP; JNK1\/MAPK8-associated membrane protein"
				},
				{
					"name":"120846341 midnolin isoform X1\tK29091 MIDN; midnolin"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic proteasome",
		"children":[
		{
			"name":"Core particles (20S proteasome)"
		},
		{
			"name":"Bacterial regulatory particles"
		},
		{
			"name":"Archaeal regulatory particles"
		}
		]
	}
	]
}