{
	"name":"itr03032",
	"children":[
	{
		"name":"Eukaryotic type",
		"children":[
		{
			"name":"DNA Replication Initiation Factors",
			"children":[
			{
				"name":"pre-RC (pre-replication complex)",
				"children":[
				{
					"name":"116025884 origin of replication complex subunit 1A-like\tK02603 ORC1; origin recognition complex subunit 1"
				},
				{
					"name":"116023038 origin of replication complex subunit 2\tK02604 ORC2; origin recognition complex subunit 2"
				},
				{
					"name":"116012339 origin of replication complex subunit 3\tK02605 ORC3; origin recognition complex subunit 3"
				},
				{
					"name":"116005013 origin of replication complex subunit 4 isoform X1\tK02606 ORC4; origin recognition complex subunit 4"
				},
				{
					"name":"116012094 origin of replication complex subunit 5-like\tK02607 ORC5; origin recognition complex subunit 5"
				},
				{
					"name":"115997877 origin of replication complex subunit 6\tK02608 ORC6; origin recognition complex subunit 6"
				},
				{
					"name":"116000892 CDT1-like protein a, chloroplastic\tK10727 CDT1; chromatin licensing and DNA replication factor 1"
				},
				{
					"name":"116005282 CDT1-like protein a, chloroplastic\tK10727 CDT1; chromatin licensing and DNA replication factor 1"
				},
				{
					"name":"116017182 CDT1-like protein a, chloroplastic\tK10727 CDT1; chromatin licensing and DNA replication factor 1"
				},
				{
					"name":"116022571 CDT1-like protein a, chloroplastic\tK10727 CDT1; chromatin licensing and DNA replication factor 1"
				},
				{
					"name":"116025808 cell division control protein 6 homolog B\tK02213 CDC6; cell division control protein 6"
				},
				{
					"name":"116000889 DNA replication licensing factor MCM2\tK02540 MCM2; DNA replication licensing factor MCM2 [EC:5.6.2.3]"
				},
				{
					"name":"116031998 DNA replication licensing factor MCM3 homolog 2 isoform X1\tK02541 MCM3; DNA replication licensing factor MCM3 [EC:5.6.2.3]"
				},
				{
					"name":"116003580 DNA replication licensing factor MCM4\tK02212 MCM4; DNA replication licensing factor MCM4 [EC:5.6.2.3]"
				},
				{
					"name":"116024723 DNA replication licensing factor MCM5\tK02209 MCM5; DNA replication licensing factor MCM5 [EC:5.6.2.3]"
				},
				{
					"name":"115998152 DNA replication licensing factor MCM6\tK02542 MCM6; DNA replication licensing factor MCM6 [EC:5.6.2.3]"
				},
				{
					"name":"116005615 DNA replication licensing factor MCM7\tK02210 MCM7; DNA replication licensing factor MCM7 [EC:5.6.2.3]"
				}
				]
			},
			{
				"name":"CDK (cyclin dependent kinase)",
				"children":[
				{
					"name":"116006312 cyclin-A2-1-like\tK06627 CCNA; cyclin-A"
				},
				{
					"name":"116022479 putative cyclin-A3-1\tK06627 CCNA; cyclin-A"
				},
				{
					"name":"116022577 cyclin-A1-1-like\tK06627 CCNA; cyclin-A"
				},
				{
					"name":"116022804 cyclin-A2-2-like\tK06627 CCNA; cyclin-A"
				},
				{
					"name":"116022891 G2\/mitotic-specific cyclin C13-1-like isoform X1\tK06627 CCNA; cyclin-A"
				},
				{
					"name":"116029353 G2\/mitotic-specific cyclin C13-1-like\tK06627 CCNA; cyclin-A"
				},
				{
					"name":"116006966 cell division control protein 2 homolog A\tK02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]"
				},
				{
					"name":"116029364 cell division control protein 2 homolog A-like\tK02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]"
				}
				]
			},
			{
				"name":"DDK (Dbf-4 dependent kinase)",
				"children":[
				{
					"name":"116002255 uncharacterized protein LOC116002255\tK02214 CDC7; cell division control protein 7 [EC:2.7.11.1]"
				}
				]
			},
			{
				"name":"GINS complex",
				"children":[
				{
					"name":"116007556 DNA replication complex GINS protein PSF1 isoform X1\tK10732 GINS1; GINS complex subunit 1"
				},
				{
					"name":"116021207 DNA replication complex GINS protein PSF2 isoform X1\tK10733 GINS2; GINS complex subunit 2"
				},
				{
					"name":"116000109 probable DNA replication complex GINS protein PSF3\tK10734 GINS3; GINS complex subunit 3"
				},
				{
					"name":"116016350 probable DNA replication complex GINS protein PSF3\tK10734 GINS3; GINS complex subunit 3"
				},
				{
					"name":"115999049 DNA replication complex GINS protein SLD5\tK10735 GINS4; GINS complex subunit 4"
				}
				]
			},
			{
				"name":"Other initiation factors",
				"children":[
				{
					"name":"115997100 DNA topoisomerase 2-binding protein 1-A isoform X1\tK10728 TOPBP1; topoisomerase (DNA) II binding protein 1"
				},
				{
					"name":"116015062 BRCT domain-containing protein At4g02110\tK10728 TOPBP1; topoisomerase (DNA) II binding protein 1"
				},
				{
					"name":"116024926 ATP-dependent DNA helicase Q-like 5\tK10730 RECQL4; ATP-dependent DNA helicase Q4 [EC:5.6.2.4]"
				},
				{
					"name":"116004235 cell division control protein 45 homolog\tK06628 CDC45; cell division control protein 45"
				},
				{
					"name":"116016437 probable DNA helicase MCM8\tK10737 MCM8; DNA helicase MCM8 [EC:5.6.2.4]"
				},
				{
					"name":"116029973 probable DNA helicase MCM9 isoform X1\tK10738 MCM9; DNA helicase MCM9 [EC:5.6.2.4]"
				},
				{
					"name":"115999366 protein MCM10 homolog isoform X1\tK10736 MCM10; minichromosome maintenance protein 10"
				},
				{
					"name":"115999202 mini-chromosome maintenance complex-binding protein\tK28390 MCMBP; minichromosome maintenance complex-binding protein"
				}
				]
			}
			]
		},
		{
			"name":"DNA Replication Elongation Factors",
			"children":[
			{
				"name":"DNA polymerase alpha \/ primase complex",
				"children":[
				{
					"name":"116018769 DNA polymerase alpha catalytic subunit\tK02320 POLA1; DNA polymerase alpha subunit A [EC:2.7.7.7]"
				},
				{
					"name":"116027637 DNA polymerase alpha subunit B\tK02321 POLA2; DNA polymerase alpha subunit B"
				},
				{
					"name":"115999914 DNA primase small subunit-like\tK02684 PRI1; DNA primase small subunit [EC:2.7.7.102]"
				},
				{
					"name":"115999943 DNA primase small subunit-like\tK02684 PRI1; DNA primase small subunit [EC:2.7.7.102]"
				},
				{
					"name":"116025711 probable DNA primase large subunit\tK02685 PRI2; DNA primase large subunit"
				}
				]
			},
			{
				"name":"DNA polymerase epsilon complex",
				"children":[
				{
					"name":"116004969 DNA polymerase epsilon catalytic subunit A-like\tK02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]"
				},
				{
					"name":"115997504 DNA polymerase epsilon subunit B\tK02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]"
				},
				{
					"name":"116024781 DNA polymerase epsilon subunit 3\tK02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]"
				}
				]
			},
			{
				"name":"DNA polymerase delta complex",
				"children":[
				{
					"name":"116031032 DNA polymerase delta catalytic subunit\tK02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]"
				},
				{
					"name":"116030198 DNA polymerase delta small subunit\tK02328 POLD2; DNA polymerase delta subunit 2"
				},
				{
					"name":"116011305 uncharacterized protein LOC116011305\tK03504 POLD3; DNA polymerase delta subunit 3"
				},
				{
					"name":"116021792 uncharacterized protein LOC116021792\tK03504 POLD3; DNA polymerase delta subunit 3"
				},
				{
					"name":"116016999 uncharacterized protein LOC116016999\tK03505 POLD4; DNA polymerase delta subunit 4"
				}
				]
			},
			{
				"name":"DNA polymerase gamma complex (mitochondrial)"
			},
			{
				"name":"RPA (replication protein A)",
				"children":[
				{
					"name":"115998866 replication protein A 70 kDa DNA-binding subunit A\tK07466 RFA1; replication factor A1"
				},
				{
					"name":"116009334 replication protein A 70 kDa DNA-binding subunit B-like\tK07466 RFA1; replication factor A1"
				},
				{
					"name":"116022945 replication protein A 70 kDa DNA-binding subunit B\tK07466 RFA1; replication factor A1"
				},
				{
					"name":"116023268 replication protein A 70 kDa DNA-binding subunit A\tK07466 RFA1; replication factor A1"
				},
				{
					"name":"116012768 replication protein A 32 kDa subunit A-like isoform X1\tK10739 RFA2; replication factor A2"
				},
				{
					"name":"116012770 replication protein A 32 kDa subunit B-like isoform X1\tK10739 RFA2; replication factor A2"
				},
				{
					"name":"116013178 replication protein A 32 kDa subunit A-like\tK10739 RFA2; replication factor A2"
				},
				{
					"name":"116030370 replication protein A 32 kDa subunit B isoform X1\tK10739 RFA2; replication factor A2"
				},
				{
					"name":"116007115 replication protein A 14 kDa subunit B-like\tK10740 RPA3; replication factor A3"
				}
				]
			},
			{
				"name":"RFC (replication factor C)",
				"children":[
				{
					"name":"116025503 replication factor C subunit 1\tK10754 RFC1; replication factor C subunit 1"
				},
				{
					"name":"116001632 replication factor C subunit 2\tK10755 RFC2_4; replication factor C subunit 2\/4"
				},
				{
					"name":"116020797 replication factor C subunit 2 isoform X1\tK10755 RFC2_4; replication factor C subunit 2\/4"
				},
				{
					"name":"115998677 uncharacterized protein LOC115998677 isoform X1\tK10756 RFC3_5; replication factor C subunit 3\/5"
				},
				{
					"name":"116006883 replication factor C subunit 3\tK10756 RFC3_5; replication factor C subunit 3\/5"
				},
				{
					"name":"116022592 replication factor C subunit 3\tK10756 RFC3_5; replication factor C subunit 3\/5"
				},
				{
					"name":"116033970 uncharacterized protein LOC116033970\tK10756 RFC3_5; replication factor C subunit 3\/5"
				}
				]
			},
			{
				"name":"RNase H",
				"children":[
				{
					"name":"115999827 ribonuclease H2 subunit A\tK10743 RNASEH2A; ribonuclease H2 subunit A [EC:3.1.26.4]"
				},
				{
					"name":"116021744 ribonuclease H2 subunit B\tK10744 RNASEH2B; ribonuclease H2 subunit B"
				},
				{
					"name":"116032944 uncharacterized protein C12B10.15c\tK10745 RNASEH2C; ribonuclease H2 subunit C"
				}
				]
			},
			{
				"name":"Other elongation factors",
				"children":[
				{
					"name":"116025371 proliferating cell nuclear antigen\tK04802 PCNA; proliferating cell nuclear antigen"
				},
				{
					"name":"115996814 DNA replication ATP-dependent helicase\/nuclease JHS1 isoform X1\tK10742 DNA2; DNA replication ATP-dependent helicase\/nuclease Dna2 [EC:5.6.2.3 3.1.-.-]"
				},
				{
					"name":"116031715 flap endonuclease 1 isoform X1\tK04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]"
				},
				{
					"name":"115996816 exonuclease 1\tK10746 EXO1; exonuclease 1 [EC:3.1.-.-]"
				},
				{
					"name":"116032040 exonuclease 1\tK10746 EXO1; exonuclease 1 [EC:3.1.-.-]"
				},
				{
					"name":"116011337 DNA annealing helicase and endonuclease ZRANB3 isoform X1\tK25861 ZRANB3; DNA annealing helicase and endonuclease ZRANB3 [EC:5.6.2.- 3.1.-.-]"
				},
				{
					"name":"116017009 DNA ligase 1\tK10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]"
				},
				{
					"name":"116000896 uncharacterized protein LOC116000896 isoform X1\tK26118 ATAD5; ATPase family AAA domain-containing protein 5"
				}
				]
			}
			]
		},
		{
			"name":"DNA Replication Termination Factors",
			"children":[
			{
				"name":"DNA methylation enzymes",
				"children":[
				{
					"name":"115995602 DNA (cytosine-5)-methyltransferase CMT3-like\tK00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]"
				},
				{
					"name":"116002081 DNA (cytosine-5)-methyltransferase CMT2-like\tK00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]"
				},
				{
					"name":"116013494 DNA (cytosine-5)-methyltransferase 1B-like\tK00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]"
				},
				{
					"name":"116016885 DNA (cytosine-5)-methyltransferase CMT1-like\tK00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]"
				},
				{
					"name":"116029082 DNA (cytosine-5)-methyltransferase 1A-like\tK00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]"
				},
				{
					"name":"116029365 DNA (cytosine-5)-methyltransferase 1B-like isoform X1\tK00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]"
				},
				{
					"name":"116006465 uncharacterized protein LOC116006465\tK17398 DNMT3A; DNA (cytosine-5)-methyltransferase 3A [EC:2.1.1.37]"
				}
				]
			},
			{
				"name":"Prevention of re-replication factors",
				"children":[
				{
					"name":"115999091 G2\/mitotic-specific cyclin-2-like\tK21777 CCNB; G2\/mitotic-specific cyclin-B, other"
				},
				{
					"name":"116007153 G2\/mitotic-specific cyclin-2-like isoform X1\tK21777 CCNB; G2\/mitotic-specific cyclin-B, other"
				},
				{
					"name":"116012417 G2\/mitotic-specific cyclin-2-like\tK21777 CCNB; G2\/mitotic-specific cyclin-B, other"
				},
				{
					"name":"116017717 G2\/mitotic-specific cyclin S13-7-like\tK21777 CCNB; G2\/mitotic-specific cyclin-B, other"
				},
				{
					"name":"116019116 putative cyclin-B3-1 isoform X1\tK21777 CCNB; G2\/mitotic-specific cyclin-B, other"
				},
				{
					"name":"116020534 G2\/mitotic-specific cyclin-2-like\tK21777 CCNB; G2\/mitotic-specific cyclin-B, other"
				},
				{
					"name":"116024899 cyclin-SDS\tK21777 CCNB; G2\/mitotic-specific cyclin-B, other"
				},
				{
					"name":"116025846 G2\/mitotic-specific cyclin S13-7-like\tK21777 CCNB; G2\/mitotic-specific cyclin-B, other"
				},
				{
					"name":"116032248 LOW QUALITY PROTEIN: cyclin-B2-3\tK21777 CCNB; G2\/mitotic-specific cyclin-B, other"
				},
				{
					"name":"116032630 G2\/mitotic-specific cyclin-2-like\tK21777 CCNB; G2\/mitotic-specific cyclin-B, other"
				},
				{
					"name":"116033248 G2\/mitotic-specific cyclin S13-7-like\tK21777 CCNB; G2\/mitotic-specific cyclin-B, other"
				}
				]
			},
			{
				"name":"Telomere proteins",
				"children":[
				{
					"name":"Shelterin complex",
					"children":[
					{
						"name":"116025316 uncharacterized protein LOC116025316\tK11111 TERF2; telomeric repeat-binding factor 2"
					}
					]
				},
				{
					"name":"TERB1-TERB2-MAJIN complex"
				},
				{
					"name":"CST complex (animals)",
					"children":[
					{
						"name":"116016608 CST complex subunit STN1 isoform X1\tK23312 STN1; CST complex subunit STN1"
					},
					{
						"name":"116017390 CST complex subunit TEN1\tK23313 TEN1; CST complex subunit TEN1"
					}
					]
				},
				{
					"name":"CST complex (yeast)"
				},
				{
					"name":"RIF proteins"
				},
				{
					"name":"SIR proteins"
				}
				]
			},
			{
				"name":"Telomerase complex (animals)",
				"children":[
				{
					"name":"116009808 telomerase reverse transcriptase isoform X1\tK11126 TERT; telomerase reverse transcriptase [EC:2.7.7.49]"
				},
				{
					"name":"Dyskerin complex",
					"children":[
					{
						"name":"116032905 putative H\/ACA ribonucleoprotein complex subunit 1-like protein 1\tK11128 GAR1; H\/ACA ribonucleoprotein complex subunit 1"
					},
					{
						"name":"115996585 H\/ACA ribonucleoprotein complex subunit 2-like protein\tK11129 NHP2; H\/ACA ribonucleoprotein complex subunit 2"
					},
					{
						"name":"116026859 H\/ACA ribonucleoprotein complex subunit 2-like protein\tK11129 NHP2; H\/ACA ribonucleoprotein complex subunit 2"
					},
					{
						"name":"116004838 H\/ACA ribonucleoprotein complex subunit 4-like\tK11131 DKC1; H\/ACA ribonucleoprotein complex subunit 4 [EC:5.4.99.-]"
					},
					{
						"name":"116016310 H\/ACA ribonucleoprotein complex subunit 4-like\tK11131 DKC1; H\/ACA ribonucleoprotein complex subunit 4 [EC:5.4.99.-]"
					},
					{
						"name":"116016528 H\/ACA ribonucleoprotein complex subunit 4-like\tK11131 DKC1; H\/ACA ribonucleoprotein complex subunit 4 [EC:5.4.99.-]"
					}
					]
				}
				]
			},
			{
				"name":"Telomerase complex (fungi)",
				"children":[
				{
					"name":"116009808 telomerase reverse transcriptase isoform X1\tK11126 TERT; telomerase reverse transcriptase [EC:2.7.7.49]"
				},
				{
					"name":"Sm core complex",
					"children":[
					{
						"name":"115995664 small nuclear ribonucleoprotein-associated protein B'-like\tK11086 SNRPB; small nuclear ribonucleoprotein B and B'"
					},
					{
						"name":"116028568 small nuclear ribonucleoprotein-associated protein B-like\tK11086 SNRPB; small nuclear ribonucleoprotein B and B'"
					},
					{
						"name":"116004877 small nuclear ribonucleoprotein SmD1a-like\tK11087 SNRPD1; small nuclear ribonucleoprotein D1"
					},
					{
						"name":"116017117 small nuclear ribonucleoprotein SmD1a\tK11087 SNRPD1; small nuclear ribonucleoprotein D1"
					},
					{
						"name":"116016935 small nuclear ribonucleoprotein Sm D2-like isoform X1\tK11096 SNRPD2; small nuclear ribonucleoprotein D2"
					},
					{
						"name":"116025705 small nuclear ribonucleoprotein Sm D2\tK11096 SNRPD2; small nuclear ribonucleoprotein D2"
					},
					{
						"name":"115999923 small nuclear ribonucleoprotein SmD3b-like\tK11088 SNRPD3; small nuclear ribonucleoprotein D3"
					},
					{
						"name":"116012308 small nuclear ribonucleoprotein SmD3b-like\tK11088 SNRPD3; small nuclear ribonucleoprotein D3"
					},
					{
						"name":"116019388 small nuclear ribonucleoprotein SmD3a-like\tK11088 SNRPD3; small nuclear ribonucleoprotein D3"
					},
					{
						"name":"116010338 small nuclear ribonucleoprotein E-like\tK11097 SNRPE; small nuclear ribonucleoprotein E"
					},
					{
						"name":"115997118 probable small nuclear ribonucleoprotein F\tK11098 SNRPF; small nuclear ribonucleoprotein F"
					},
					{
						"name":"116009922 probable small nuclear ribonucleoprotein F\tK11098 SNRPF; small nuclear ribonucleoprotein F"
					},
					{
						"name":"116014124 probable small nuclear ribonucleoprotein G\tK11099 SNRPG; small nuclear ribonucleoprotein G"
					},
					{
						"name":"116030170 probable small nuclear ribonucleoprotein G\tK11099 SNRPG; small nuclear ribonucleoprotein G"
					}
					]
				}
				]
			},
			{
				"name":"ELG1-RFC complex",
				"children":[
				{
					"name":"116001632 replication factor C subunit 2\tK10755 RFC2_4; replication factor C subunit 2\/4"
				},
				{
					"name":"116020797 replication factor C subunit 2 isoform X1\tK10755 RFC2_4; replication factor C subunit 2\/4"
				},
				{
					"name":"115998677 uncharacterized protein LOC115998677 isoform X1\tK10756 RFC3_5; replication factor C subunit 3\/5"
				},
				{
					"name":"116006883 replication factor C subunit 3\tK10756 RFC3_5; replication factor C subunit 3\/5"
				},
				{
					"name":"116022592 replication factor C subunit 3\tK10756 RFC3_5; replication factor C subunit 3\/5"
				},
				{
					"name":"116033970 uncharacterized protein LOC116033970\tK10756 RFC3_5; replication factor C subunit 3\/5"
				}
				]
			},
			{
				"name":"MRN complex",
				"children":[
				{
					"name":"116019084 double-strand break repair protein MRE11 isoform X1\tK10865 MRE11; double-strand break repair protein MRE11"
				},
				{
					"name":"116023040 DNA repair protein RAD50\tK10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]"
				},
				{
					"name":"116011817 nijmegen breakage syndrome 1 protein\tK10867 NBN; nibrin"
				}
				]
			},
			{
				"name":"Other termination factors",
				"children":[
				{
					"name":"116010243 serine\/threonine-protein kinase ATM\tK04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]"
				},
				{
					"name":"116031596 ATP-dependent DNA helicase Q-like SIM isoform X1\tK10900 WRN; werner syndrome ATP-dependent helicase [EC:5.6.2.4]"
				},
				{
					"name":"115998179 ATP-dependent DNA helicase Q-like 3 isoform X1\tK10901 BLM; bloom syndrome protein [EC:5.6.2.4]"
				},
				{
					"name":"116028489 ATP-dependent DNA helicase Q-like 4A\tK10901 BLM; bloom syndrome protein [EC:5.6.2.4]"
				},
				{
					"name":"116027659 DNA repair endonuclease UVH1\tK10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]"
				},
				{
					"name":"116003552 poly [ADP-ribose] polymerase 1 isoform X1\tK24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30]"
				},
				{
					"name":"116028709 poly [ADP-ribose] polymerase 2\tK28005 PARP2; poly [ADP-ribose] polymerase 2 [EC:2.4.2.30]"
				},
				{
					"name":"115999884 uncharacterized protein LOC115999884\tK11135 PINX1; Pin2-interacting protein X1"
				},
				{
					"name":"116009733 regulator of telomere elongation helicase 1 homolog\tK11136 RTEL1; regulator of telomere elongation helicase 1 [EC:5.6.2.3]"
				},
				{
					"name":"116009923 telomere length regulation protein TEL2 homolog isoform X1\tK11137 TELO2; telomere length regulation protein"
				},
				{
					"name":"116001831 uncharacterized protein LOC116001831 isoform X1\tK11138 RIF1; telomere-associated protein RIF1"
				},
				{
					"name":"116011676 ATP-dependent DNA helicase PIF1-like\tK15255 PIF1; ATP-dependent DNA helicase PIF1 [EC:5.6.2.3]"
				},
				{
					"name":"116003812 transcription factor Pur-alpha 1-like\tK21772 PURA; transcriptional activator protein Pur-alpha"
				},
				{
					"name":"116024689 transcription factor Pur-alpha 1-like isoform X1\tK21772 PURA; transcriptional activator protein Pur-alpha"
				},
				{
					"name":"116028755 telomerase Cajal body protein 1\tK23314 WRAP53; telomerase Cajal body protein 1"
				},
				{
					"name":"116030292 replication stress response regulator SDE2 isoform X1\tK25059 SDE2; replication stress response regulator SDE2"
				},
				{
					"name":"116026194 replication termination factor 2\tK25186 RTF2; replication termination factor 2"
				}
				]
			}
			]
		},
		{
			"name":"DNA Topoisomerases",
			"children":[
			{
				"name":"116029321 DNA topoisomerase 1 alpha-like isoform X1\tK03163 TOP1; DNA topoisomerase I [EC:5.6.2.1]"
			},
			{
				"name":"116030419 DNA topoisomerase 2\tK03164 TOP2; DNA topoisomerase II [EC:5.6.2.2]"
			},
			{
				"name":"115998059 DNA topoisomerase 3-alpha isoform X1\tK03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]"
			},
			{
				"name":"116016675 DNA topoisomerase 3-beta isoform X1\tK03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]"
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic type",
		"children":[
		{
			"name":"DNA Replication Initiation Factors",
			"children":[
			{
				"name":"Initiation factors (bacterial)",
				"children":[
				{
					"name":"116009768 single-stranded DNA-binding protein, mitochondrial isoform X1\tK03111 ssb; single-strand DNA-binding protein"
				}
				]
			},
			{
				"name":"Initiation factors (archaeal)"
			}
			]
		},
		{
			"name":"DNA Replication Elongation Factors",
			"children":[
			{
				"name":"Elongation factors (bacterial)",
				"children":[
				{
					"name":"DNA polymerase III holoenzyme"
				},
				{
					"name":"RNase H"
				},
				{
					"name":"Other elongation factors",
					"children":[
					{
						"name":"116001174 DNA polymerase I A, chloroplastic\/mitochondrial-like\tK02335 polA; DNA polymerase I [EC:2.7.7.7]"
					}
					]
				}
				]
			},
			{
				"name":"Elongation factors (archaeal)",
				"children":[
				{
					"name":"B-family DNA polymerases"
				},
				{
					"name":"D-family DNA polymerases"
				},
				{
					"name":"RNase H"
				},
				{
					"name":"RFC (replication factor C)"
				},
				{
					"name":"Other elongation factors",
					"children":[
					{
						"name":"115996814 DNA replication ATP-dependent helicase\/nuclease JHS1 isoform X1\tK10742 DNA2; DNA replication ATP-dependent helicase\/nuclease Dna2 [EC:5.6.2.3 3.1.-.-]"
					},
					{
						"name":"116031715 flap endonuclease 1 isoform X1\tK04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]"
					},
					{
						"name":"116017009 DNA ligase 1\tK10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"DNA Replication Termination Factors",
			"children":[
			{
				"name":"Terminus site-binding protein"
			},
			{
				"name":"DNA methylation enzymes"
			},
			{
				"name":"Prevention of re-replication factors"
			}
			]
		},
		{
			"name":"DNA Topoisomerases",
			"children":[
			{
				"name":"116006953 DNA gyrase subunit A, chloroplastic\/mitochondrial\tK02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]"
			},
			{
				"name":"116007274 DNA gyrase subunit B, chloroplastic\/mitochondrial-like\tK02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]"
			},
			{
				"name":"116003796 DNA topoisomerase 6 subunit B isoform X1\tK03167 top6B; DNA topoisomerase VI subunit B [EC:5.6.2.2]"
			}
			]
		}
		]
	}
	]
}