{
	"name":"kmx04121",
	"children":[
	{
		"name":"Ubiquitins and ubiquitin-like proteins",
		"children":[
		{
			"name":"Ubiquitins",
			"children":[
			{
				"name":"KLMA_20442 UBI4; ubiquitin\tK08770 UBB_C; ubiquitin B\/C"
			},
			{
				"name":"KLMA_30712 RPL40B; ubiquitin-60S ribosomal protein L40\tK02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e"
			},
			{
				"name":"KLMA_50559 ubi3; ubiquitin-40S ribosomal protein S27a\tK02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae"
			}
			]
		},
		{
			"name":"Ubiquitin-like proteins (UBLs)",
			"children":[
			{
				"name":"KLMA_80372 ATG8; autophagy-related protein 8\tK08341 GABARAP; GABA(A) receptor-associated protein"
			},
			{
				"name":"KLMA_10251 ATG12; autophagy-related protein 12\tK08336 ATG12; ubiquitin-like protein ATG12"
			},
			{
				"name":"KLMA_50400 URM1; ubiquitin-related modifier 1\tK12161 URM1; ubiquitin related modifier 1"
			}
			]
		}
		]
	},
	{
		"name":"Ubiquitin-activating enzymes (E1)",
		"children":[
		{
			"name":"Ubiquitin activating enzyme",
			"children":[
			{
				"name":"KLMA_30033 UBA1; ubiquitin-activating enzyme E1 1\tK03178 UBE1; ubiquitin-activating enzyme E1 [EC:6.2.1.45]"
			}
			]
		},
		{
			"name":"UBL-activating enzymes",
			"children":[
			{
				"name":"KLMA_20499 AOS1; DNA damage tolerance protein RHC31\tK10684 UBLE1A; ubiquitin-like 1-activating enzyme E1 A [EC:6.2.1.45]"
			},
			{
				"name":"KLMA_20577 UBA2; ubiquitin-activating enzyme E1-like protein\tK10685 UBLE1B; ubiquitin-like 1-activating enzyme E1 B [EC:6.2.1.45]"
			},
			{
				"name":"KLMA_80286 UBA3; NEDD8-activating enzyme E1 catalytic subunit\tK10686 UBA3; NEDD8-activating enzyme E1 [EC:6.2.1.64]"
			},
			{
				"name":"KLMA_70450 ULA1; NEDD8-activating enzyme E1 regulatory subunit\tK04532 NAE1; NEDD8-activating enzyme E1 regulatory subunit"
			},
			{
				"name":"KLMA_20445 UBA4; adenylyltransferase and sulfurtransferase UBA4\tK11996 MOCS3; adenylyltransferase and sulfurtransferase [EC:2.7.7.80 2.8.1.11]"
			},
			{
				"name":"KLMA_40433 ATG7; autophagy-related protein 7\tK08337 ATG7; ubiquitin-like modifier-activating enzyme ATG7"
			}
			]
		}
		]
	},
	{
		"name":"Ubiquitin-conjugating enzymes (E2)",
		"children":[
		{
			"name":"Ubiquitin-conjugating enzymes",
			"children":[
			{
				"name":"KLMA_10247 UBC2; ubiquitin-conjugating enzyme E2 2\tK10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]"
			},
			{
				"name":"KLMA_70365 UBC4; ubiquitin-conjugating enzyme E2 4\tK06689 UBE2D; ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]"
			},
			{
				"name":"KLMA_40380 UBC7; ubiquitin-conjugating enzyme E2-18 kDa\tK04555 UBE2G2; ubiquitin-conjugating enzyme E2 G2 [EC:2.3.2.23]"
			},
			{
				"name":"KLMA_10550 UBC8; ubiquitin-conjugating enzyme E2-24 kDa\tK10576 UBE2H; ubiquitin-conjugating enzyme E2 H [EC:2.3.2.23]"
			},
			{
				"name":"KLMA_80362 UBC6; ubiquitin-conjugating enzyme E2 6\tK04554 UBE2J2; ubiquitin-conjugating enzyme E2 J2 [EC:2.3.2.23]"
			},
			{
				"name":"KLMA_40020 UBC1; ubiquitin-conjugating enzyme E2-24 kDa\tK04649 UBE2K; ubiquitin-conjugating enzyme (huntingtin interacting protein 2) [EC:2.3.2.23]"
			},
			{
				"name":"KLMA_30298 UBC13; ubiquitin-conjugating enzyme E2 13\tK10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]"
			},
			{
				"name":"KLMA_20706 CDC34; ubiquitin-conjugating enzyme E2-34 kDa\tK02207 UBE2R; ubiquitin-conjugating enzyme E2 R [EC:2.3.2.23]"
			},
			{
				"name":"KLMA_20535 ubiquitin-conjugating enzyme E2-21 kDa\tK10689 PEX4; peroxin-4 [EC:2.3.2.23]"
			}
			]
		},
		{
			"name":"UBL-conjugating enzymes",
			"children":[
			{
				"name":"KLMA_70064 UBC9; SUMO-conjugating enzyme UBC9\tK10577 UBE2I; ubiquitin-conjugating enzyme E2 I"
			},
			{
				"name":"KLMA_30316 UBC12; NEDD8-conjugating enzyme UBC12\tK10579 UBE2M; ubiquitin-conjugating enzyme E2 M [EC:2.3.2.34]"
			},
			{
				"name":"KLMA_60454 ATG3; autophagy-related protein 3\tK08343 ATG3; ubiquitin-like-conjugating enzyme ATG3"
			},
			{
				"name":"KLMA_80409 ATG10; autophagy-related protein 10\tK08338 ATG10; ubiquitin-like-conjugating enzyme ATG10"
			}
			]
		}
		]
	},
	{
		"name":"Ubiquitin ligases (E3)",
		"children":[
		{
			"name":"HECT type E3",
			"children":[
			{
				"name":"KLMA_60008 HUL5; probable E3 ubiquitin-protein ligase HUL5\tK10589 UBE3C; ubiquitin-protein ligase E3 C [EC:2.3.2.26]"
			},
			{
				"name":"KLMA_40489 uncharacterized protein\tK20803 UBE3D; ubiquitin-protein ligase E3 D [EC:2.3.2.26]"
			},
			{
				"name":"KLMA_30059 UFD4; ubiquitin fusion degradation protein 4\tK10590 TRIP12; E3 ubiquitin-protein ligase TRIP12 [EC:2.3.2.26]"
			},
			{
				"name":"KLMA_70412 RSP5; E3 ubiquitin-protein ligase RSP5\tK10591 NEDD4; E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26]"
			},
			{
				"name":"KLMA_40567 TOM1; probable E3 ubiquitin-protein ligase TOM1\tK10592 HUWE1; E3 ubiquitin-protein ligase HUWE1 [EC:2.3.2.26]"
			},
			{
				"name":"KLMA_10722 HUL4; probable E3 ubiquitin-protein ligase HUL4\tK12232 HECTD2; E3 ubiquitin-protein ligase HECTD2 [EC:2.3.2.26]"
			},
			{
				"name":"HECT type E3 associated proteins"
			}
			]
		},
		{
			"name":"U-box type E3",
			"children":[
			{
				"name":"KLMA_60503 UFD2; ubiquitin conjugation factor E4\tK10597 UBE4B; ubiquitin conjugation factor E4 B [EC:2.3.2.27]"
			},
			{
				"name":"KLMA_10672 PRP19; pre-mRNA-splicing factor 19\tK10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]"
			}
			]
		},
		{
			"name":"Single Ring-finger type E3",
			"children":[
			{
				"name":"BRE1 proteins",
				"children":[
				{
					"name":"KLMA_40454 BRE1; E3 ubiquitin-protein ligase BRE1\tK10696 BRE1; E3 ubiquitin-protein ligase BRE1 [EC:2.3.2.27]"
				}
				]
			},
			{
				"name":"CBL proteins"
			},
			{
				"name":"SINA (Seven in absentia) proteins"
			},
			{
				"name":"Ligand of Numb proteins"
			},
			{
				"name":"March proteins",
				"children":[
				{
					"name":"KLMA_40346 SSM4; protein SSM4\tK10661 MARCH6; E3 ubiquitin-protein ligase MARCH6 [EC:2.3.2.27]"
				}
				]
			},
			{
				"name":"MDM2\/MDM4 proteins"
			},
			{
				"name":"NFX1 proteins",
				"children":[
				{
					"name":"KLMA_80129 FAP1; FKBP12-associated protein 1\tK12236 NFX1; transcriptional repressor NF-X1"
				}
				]
			},
			{
				"name":"Pellino proteins"
			},
			{
				"name":"Peripheral membrane proteins",
				"children":[
				{
					"name":"KLMA_60093 PEX10; peroxisome biogenesis factor 10\tK13346 PEX10; peroxin-10 [EC:2.3.2.27]"
				},
				{
					"name":"KLMA_40387 peroxisome assembly protein 12\tK13345 PEX12; peroxin-12"
				},
				{
					"name":"KLMA_80009 peroxisomal biogenesis factor 2\tK06664 PEX2; peroxin-2 [EC:2.3.2.27 2.3.2.36]"
				}
				]
			},
			{
				"name":"RBR proteins",
				"children":[
				{
					"name":"KLMA_10605 uncharacterized protein\tK11968 ARIH1; ariadne-1 [EC:2.3.2.31]"
				},
				{
					"name":"KLMA_50163 ITT1; translation termination inhibitor protein ITT1\tK11971 RNF14; E3 ubiquitin-protein ligase RNF14 [EC:2.3.2.31]"
				}
				]
			},
			{
				"name":"TRAF proteins"
			},
			{
				"name":"TRIM\/RBCC proteins"
			},
			{
				"name":"UBR box proteins",
				"children":[
				{
					"name":"KLMA_30209 UBR1; E3 ubiquitin-protein ligase UBR1\tK10625 UBR1; E3 ubiquitin-protein ligase UBR1 [EC:2.3.2.27]"
				},
				{
					"name":"KLMA_30137 mlo2; protein mlo2\tK11979 UBR7; E3 ubiquitin-protein ligase UBR7 [EC:2.3.2.27]"
				}
				]
			},
			{
				"name":"ATL proteins"
			},
			{
				"name":"Other single Ring-finger type E3",
				"children":[
				{
					"name":"KLMA_60321 ETP1; RING finger protein ETP1\tK10632 BRAP; BRCA1-associated protein [EC:2.3.2.27]"
				},
				{
					"name":"KLMA_70177 MOT2; general negative regulator of transcription subunit 4\tK10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]"
				},
				{
					"name":"KLMA_30560 RKR1; uncharacterized protein\tK22377 LTN1; E3 ubiquitin-protein ligase listerin [EC:2.3.2.27]"
				},
				{
					"name":"KLMA_30501 RAD18; postreplication repair E3 ubiquitin-protein ligase RAD18\tK10627 RAD18; E3 ubiquitin-protein ligase RAD18 [EC:2.3.2.27]"
				},
				{
					"name":"KLMA_10617 MAG2; RING-finger protein MAG2\tK26979 RNF10; E3 ubiquitin-protein ligase RNF10 [EC:2.3.2.27]"
				},
				{
					"name":"KLMA_20322 SNU66; U4\/U6.U5 small nuclear ribonucleoprotein\tK11984 SART1; U4\/U6.U5 tri-snRNP-associated protein 1"
				},
				{
					"name":"KLMA_20133 IRC20; hypothetical protein\tK15710 SHPRH; E3 ubiquitin-protein ligase SHPRH [EC:5.6.2.- 2.3.2.27]"
				},
				{
					"name":"KLMA_10257 HRD1; ERAD-associated E3 ubiquitin-protein ligase HRD1\tK10601 SYVN1; E3 ubiquitin-protein ligase synoviolin [EC:2.3.2.27]"
				},
				{
					"name":"KLMA_60092 uncharacterized protein\tK22381 ZNF598; E3 ubiquitin-protein ligase ZNF598 [EC:2.3.2.27]"
				},
				{
					"name":"KLMA_60330 hypothetical protein\tK16276 K16276; zinc finger protein-like protein"
				},
				{
					"name":"KLMA_60318 TUL1; transmembrane E3 ubiquitin-protein ligase 1\tK23788 TUL1; transmembrane E3 ubiquitin-protein ligase [EC:2.3.2.27]"
				},
				{
					"name":"KLMA_60242 DMA2; E3 ubiquitin-protein ligase DMA2\tK23787 DMA1_2; E3 ubiquitin-protein ligase DMA1\/2 [EC:2.3.2.27]"
				}
				]
			}
			]
		},
		{
			"name":"Atypical E3",
			"children":[
			{
				"name":"KLMA_80079 NSE1; non-structural maintenance of chromosomes element 1\tK22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27]"
			}
			]
		},
		{
			"name":"UBL E3 ligases",
			"children":[
			{
				"name":"KLMA_70161 HRT1; RING-box protein HRT1\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
			},
			{
				"name":"KLMA_30651 SIZ1; E3 SUMO-protein ligase SIZ1\tK04706 PIAS1; E3 SUMO-protein ligase PIAS1 [EC:2.3.2.-]"
			},
			{
				"name":"KLMA_10563 MMS21; E3 SUMO-protein ligase MMS21\tK22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]"
			},
			{
				"name":"KLMA_40469 CST9; hypothetical protein\tK25662 RNF212; E3 SUMO-protein ligase RNF212 [EC:2.3.2.-]"
			},
			{
				"name":"KLMA_50485 DCN1; defective in cullin neddylation protein 1\tK17822 DCUN1D1_2; DCN1-like protein 1\/2"
			}
			]
		},
		{
			"name":"Multi subunit type E3",
			"children":[
			{
				"name":"SCF complex",
				"children":[
				{
					"name":"Ring finger protein",
					"children":[
					{
						"name":"KLMA_70161 HRT1; RING-box protein HRT1\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
					}
					]
				},
				{
					"name":"Cullin",
					"children":[
					{
						"name":"KLMA_60494 CDC53; cell division control protein 53\tK03347 CUL1; cullin 1"
					}
					]
				},
				{
					"name":"Adaptor protein",
					"children":[
					{
						"name":"KLMA_60103 SKP1; suppressor of kinetochore protein 1\tK03094 SKP1; S-phase kinase-associated protein 1"
					}
					]
				},
				{
					"name":"Target recognizing subunit (F-box)",
					"children":[
					{
						"name":"KLMA_40339 MET30; F-box protein MET30\tK10259 MET30; F-box and WD-40 domain protein MET30"
					},
					{
						"name":"KLMA_20775 CDC4; WD40 domain-containing protein\tK03361 CDC4; F-box and WD-40 domain protein CDC4"
					},
					{
						"name":"KLMA_40439 Fbxl7; hypothetical protein\tK10273 FBXL7; F-box and leucine-rich repeat protein 7"
					},
					{
						"name":"KLMA_40344 JHD1; JmjC domain-containing histone demethylation protein 1\tK10276 FBXL10_11; F-box and leucine-rich repeat protein 10\/11 [EC:1.14.11.27]"
					},
					{
						"name":"KLMA_70111 GRR1; SCF E3 ubiquitin ligase complex F-box protein GRR1\tK03360 GRR1; F-box and leucine-rich repeat protein GRR1"
					},
					{
						"name":"KLMA_10403 DIA2; protein DIA2\tK15068 DIA2; protein DIA2"
					},
					{
						"name":"KLMA_40157 HRT3; F-box protein HRT3\tK10295 FBXO9; F-box protein 9"
					},
					{
						"name":"KLMA_50275 F-box-like family protein\tK15070 MDM30; mitochondrial distribution and morphology protein 30"
					},
					{
						"name":"KLMA_10149 RCY1; recyclin-1\tK15071 RCY1; recyclin-1"
					},
					{
						"name":"KLMA_50083 SAF1; SCF-associated factor 1\tK15072 SAF1; SCF-associated factor 1"
					},
					{
						"name":"KLMA_70263 UFO1; ubiquitin ligase complex F-box protein UFO1\tK15073 UFO1; ubiquitin ligase complex F-box protein UFO1"
					}
					]
				}
				]
			},
			{
				"name":"Cul2 complex",
				"children":[
				{
					"name":"Ring finger protein",
					"children":[
					{
						"name":"KLMA_70161 HRT1; RING-box protein HRT1\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
					}
					]
				},
				{
					"name":"Cullin"
				},
				{
					"name":"Adoptor protein",
					"children":[
					{
						"name":"KLMA_60398 elongin-C\tK03872 ELOC; elongin-C"
					}
					]
				},
				{
					"name":"Target recognizing subunit"
				}
				]
			},
			{
				"name":"Cul3 complex",
				"children":[
				{
					"name":"Ring finger protein",
					"children":[
					{
						"name":"KLMA_70161 HRT1; RING-box protein HRT1\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
					}
					]
				},
				{
					"name":"Cullin",
					"children":[
					{
						"name":"KLMA_40036 CUL3; cullin-3\tK03869 CUL3; cullin 3"
					}
					]
				},
				{
					"name":"Adoptor and target recognizing subunit (BTB)",
					"children":[
					{
						"name":"KLMA_50388 uncharacterized protein\tK10520 ABTB1; ankyrin repeat and BTB\/POZ domain-containing protein 1"
					}
					]
				}
				]
			},
			{
				"name":"Cul4 complex",
				"children":[
				{
					"name":"Ring finger protein",
					"children":[
					{
						"name":"KLMA_70161 HRT1; RING-box protein HRT1\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
					}
					]
				},
				{
					"name":"Cullin"
				},
				{
					"name":"Adoptor protein"
				},
				{
					"name":"Target recognizing subunit (DCAF)",
					"children":[
					{
						"name":"KLMA_50334 uncharacterized protein\tK11805 DCAF7; DDB1- and CUL4-associated factor 7"
					},
					{
						"name":"KLMA_30222 DCAF13; protein SOF1\tK11806 DCAF13; DDB1- and CUL4-associated factor 13"
					},
					{
						"name":"KLMA_10052 GID7; glucose-induced degradation protein 7\tK22382 WDR26; WD repeat-containing protein 26"
					},
					{
						"name":"KLMA_70244 uncharacterized protein\tK24755 WDR76; WD repeat-containing protein 76"
					}
					]
				}
				]
			},
			{
				"name":"Cul5 complex",
				"children":[
				{
					"name":"Ring finger protein"
				},
				{
					"name":"Cullin"
				},
				{
					"name":"Adoptor protein",
					"children":[
					{
						"name":"KLMA_60398 elongin-C\tK03872 ELOC; elongin-C"
					}
					]
				},
				{
					"name":"Target recognizing subunit"
				}
				]
			},
			{
				"name":"Cul7 complex",
				"children":[
				{
					"name":"Ring finger protein",
					"children":[
					{
						"name":"KLMA_70161 HRT1; RING-box protein HRT1\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
					}
					]
				},
				{
					"name":"Cullin"
				},
				{
					"name":"Adaptor protein",
					"children":[
					{
						"name":"KLMA_60103 SKP1; suppressor of kinetochore protein 1\tK03094 SKP1; S-phase kinase-associated protein 1"
					}
					]
				},
				{
					"name":"Target recognizing subunit"
				}
				]
			},
			{
				"name":"Cul8 complex",
				"children":[
				{
					"name":"Ring finger protein",
					"children":[
					{
						"name":"KLMA_70161 HRT1; RING-box protein HRT1\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
					}
					]
				},
				{
					"name":"Cullin",
					"children":[
					{
						"name":"KLMA_50091 cullin\tK26124 RTT101; cullin 8"
					}
					]
				},
				{
					"name":"Adaptor protein"
				},
				{
					"name":"Target recognizing subunit",
					"children":[
					{
						"name":"KLMA_40034 MMS22; methyl methanesulfonate-sensitivity protein 22\tK26122 MMS22; E3 ubiquitin-protein ligase substrate receptor MMS22"
					}
					]
				}
				]
			},
			{
				"name":"Cul9 complex",
				"children":[
				{
					"name":"Ring finger protein",
					"children":[
					{
						"name":"KLMA_70161 HRT1; RING-box protein HRT1\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
					}
					]
				},
				{
					"name":"Cullin"
				}
				]
			},
			{
				"name":"APC\/C",
				"children":[
				{
					"name":"Ring finger protein",
					"children":[
					{
						"name":"KLMA_60132 APC11; anaphase-promoting complex subunit 11\tK03358 APC11; anaphase-promoting complex subunit 11"
					}
					]
				},
				{
					"name":"Cullin",
					"children":[
					{
						"name":"KLMA_50484 APC2; anaphase-promoting complex subunit 2\tK03349 APC2; anaphase-promoting complex subunit 2"
					}
					]
				},
				{
					"name":"Target recognizing subunit",
					"children":[
					{
						"name":"KLMA_20224 CDC20; APC\/C activator protein CDC20\tK03363 CDC20; cell division cycle 20, cofactor of APC complex"
					},
					{
						"name":"KLMA_10450 CDH1; APC\/C activator protein CDH1\tK03364 CDH1; cell division cycle 20-like protein 1, cofactor of APC complex"
					},
					{
						"name":"KLMA_60058 AMA1; meiosis-specific APC\/C activator protein AMA1\tK12782 AMA1; meiosis-specific APC\/C activator protein AMA1"
					}
					]
				},
				{
					"name":"Other subunits",
					"children":[
					{
						"name":"KLMA_20750 APC1; anaphase-promoting complex subunit 1\tK03348 APC1; anaphase-promoting complex subunit 1"
					},
					{
						"name":"KLMA_80384 CDC27; anaphase-promoting complex subunit CDC27\tK03350 APC3; anaphase-promoting complex subunit 3"
					},
					{
						"name":"KLMA_40146 hypothetical protein\tK03351 APC4; anaphase-promoting complex subunit 4"
					},
					{
						"name":"KLMA_30447 anaphase-promoting complex subunit 5\tK03352 APC5; anaphase-promoting complex subunit 5"
					},
					{
						"name":"KLMA_40367 CDC16; hypothetical protein\tK03353 APC6; anaphase-promoting complex subunit 6"
					},
					{
						"name":"KLMA_10325 CDC23; anaphase-promoting complex subunit CDC23\tK03355 APC8; anaphase-promoting complex subunit 8"
					},
					{
						"name":"KLMA_30701 DOC1; anaphase-promoting complex subunit DOC1\tK03357 APC10; anaphase-promoting complex subunit 10"
					},
					{
						"name":"KLMA_60100 hypothetical protein\tK12416 SWM1; anaphase-promoting complex subunit SWM1"
					}
					]
				}
				]
			},
			{
				"name":"BRCC complex",
				"children":[
				{
					"name":"KLMA_80356 RAD51; DNA repair protein RAD51\tK04482 RAD51; DNA repair protein RAD51"
				}
				]
			},
			{
				"name":"KPC complex"
			},
			{
				"name":"LUBAC complex"
			},
			{
				"name":"CTLH complex",
				"children":[
				{
					"name":"KLMA_60399 RMD5; sporulation protein RMD5\tK23333 RMND5; E3 ubiquitin-protein transferase RMND5 [EC:2.3.2.27]"
				},
				{
					"name":"KLMA_30686 VID30; vacuolar import and degradation protein 30\tK23334 RANBP9_10; Ran-binding protein 9\/10"
				},
				{
					"name":"KLMA_80138 FYV10; protein FYV10\tK18624 MAEA; macrophage erythroblast attacher"
				},
				{
					"name":"KLMA_80284 VID24; vacuolar import and degradation protein 24\tK23335 GID4; glucose-induced degradation protein 4"
				},
				{
					"name":"KLMA_40059 GID8; glucose-induced degradation protein 8\tK23338 GID8; glucose-induced degradation protein 8"
				},
				{
					"name":"KLMA_10052 GID7; glucose-induced degradation protein 7\tK22382 WDR26; WD repeat-containing protein 26"
				}
				]
			},
			{
				"name":"ERAD complex"
			},
			{
				"name":"LMBR1L-GP78-UBAC2 complex"
			},
			{
				"name":"STUB1-CHIC2  complex"
			},
			{
				"name":"SLX5-SLX8 complex",
				"children":[
				{
					"name":"KLMA_10201 SLX5; E3 ubiquitin-protein ligase complex SLX5-SLX8 subunit SLX5\tK22645 SLX5; E3 ubiquitin-protein ligase complex SLX5-SLX8 subunit SLX5 [EC:2.3.2.27]"
				}
				]
			},
			{
				"name":"Multi subunit type E3 associated proteins",
				"children":[
				{
					"name":"KLMA_60107 UBX5; UBX domain-containing protein 5\tK24350 UBXN7; UBX domain-containing protein 7"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Deubiquitinating enzyme (DUB)",
		"children":[
		{
			"name":"Ubiquitin-specific proteases (UBPs)",
			"children":[
			{
				"name":"UCH",
				"children":[
				{
					"name":"KLMA_20015 YUH1; ubiquitin carboxyl-terminal hydrolase YUH1\tK05609 UCHL3; ubiquitin carboxyl-terminal hydrolase L3 [EC:3.4.19.12]"
				},
				{
					"name":"KLMA_20017 uch2; ubiquitin carboxyl-terminal hydrolase isozyme L5\tK05610 UCHL5; ubiquitin carboxyl-terminal hydrolase L5 [EC:3.4.19.12]"
				}
				]
			},
			{
				"name":"UBP\/USP",
				"children":[
				{
					"name":"KLMA_40109 UBP14; ubiquitin carboxyl-terminal hydrolase 14\tK11836 USP5_13; ubiquitin carboxyl-terminal hydrolase 5\/13 [EC:3.4.19.12]"
				},
				{
					"name":"KLMA_80201 UBP15; ubiquitin carboxyl-terminal hydrolase 15\tK11838 USP7; ubiquitin carboxyl-terminal hydrolase 7 [EC:3.4.19.12]"
				},
				{
					"name":"KLMA_20028 DOA4; ubiquitin carboxyl-terminal hydrolase 4\tK11839 USP8; ubiquitin carboxyl-terminal hydrolase 8 [EC:3.4.19.12]"
				},
				{
					"name":"KLMA_20429 UBP3; ubiquitin carboxyl-terminal hydrolase 3\tK11841 USP10; ubiquitin carboxyl-terminal hydrolase 10 [EC:3.4.19.12]"
				},
				{
					"name":"KLMA_10531 UBP6; ubiquitin carboxyl-terminal hydrolase 6\tK11843 USP14; ubiquitin carboxyl-terminal hydrolase 14 [EC:3.4.19.12]"
				},
				{
					"name":"KLMA_10308 UBP8; ubiquitin carboxyl-terminal hydrolase 8\tK11366 USP22_27_51; ubiquitin carboxyl-terminal hydrolase 22\/27\/51 [EC:3.4.19.12]"
				},
				{
					"name":"KLMA_20610 UBP2; ubiquitin carboxyl-terminal hydrolase 2\tK11849 USP25; ubiquitin carboxyl-terminal hydrolase 25 [EC:3.4.19.12]"
				},
				{
					"name":"KLMA_80111 UBP1; ubiquitin carboxyl-terminal hydrolase 1\tK11870 UBP1; ubiquitin carboxyl-terminal hydrolase 1 [EC:3.4.19.12]"
				},
				{
					"name":"KLMA_30723 UBP11; ubiquitin carboxyl-terminal hydrolase 7\tK11871 UBP7_11; ubiquitin carboxyl-terminal hydrolase 7\/11 [EC:3.4.19.12]"
				},
				{
					"name":"KLMA_80360 UBP13; ubiquitin carboxyl-terminal hydrolase 13\tK11872 UBP9_13; ubiquitin carboxyl-terminal hydrolase 9\/13 [EC:3.4.19.12]"
				},
				{
					"name":"KLMA_20735 UBP10; ubiquitin carboxyl-terminal hydrolase 10\tK11873 UBP10; ubiquitin carboxyl-terminal hydrolase 10 [EC:3.4.19.12]"
				},
				{
					"name":"KLMA_10756 UBP16; hypothetical protein\tK11874 UBP16; ubiquitin carboxyl-terminal hydrolase 16 [EC:3.4.19.12]"
				}
				]
			},
			{
				"name":"OTU",
				"children":[
				{
					"name":"KLMA_60315 OTU2; OTU domain-containing protein 2\tK18342 OTUD6; OTU domain-containing protein 6 [EC:3.4.19.12]"
				}
				]
			},
			{
				"name":"MJD"
			},
			{
				"name":"MINDY",
				"children":[
				{
					"name":"KLMA_60366 uncharacterized protein\tK01309 MINDY1_2; ubiquitin carboxyl-terminal hydrolase MINDY-1\/2 [EC:3.4.19.12]"
				}
				]
			},
			{
				"name":"JAMM",
				"children":[
				{
					"name":"KLMA_70440 RPN11; 26S proteasome regulatory subunit RPN11\tK03030 PSMD14; 26S proteasome regulatory subunit N11"
				}
				]
			},
			{
				"name":"PPPDE"
			},
			{
				"name":"ZUFSP"
			},
			{
				"name":"BRISC complex"
			}
			]
		},
		{
			"name":"UBL-specific proteases (ULPs)",
			"children":[
			{
				"name":"KLMA_20214 ULP1; SUMO protease ULP1\tK08592 SENP1; sentrin-specific protease 1 [EC:3.4.22.68]"
			},
			{
				"name":"KLMA_40345 ulp2; ubiquitin-like-specific protease 2\tK08596 SENP7; sentrin-specific protease 7 [EC:3.4.22.68]"
			},
			{
				"name":"KLMA_20015 YUH1; ubiquitin carboxyl-terminal hydrolase YUH1\tK05609 UCHL3; ubiquitin carboxyl-terminal hydrolase L3 [EC:3.4.19.12]"
			},
			{
				"name":"COP9 signalosome (CSN) complex",
				"children":[
				{
					"name":"KLMA_20733 RRI1; COP9 signalosome complex subunit 5\tK09613 COPS5; COP9 signalosome complex subunit 5 [EC:3.4.-.-]"
				},
				{
					"name":"KLMA_50551 CSN9; COP9 signalosome complex subunit 9\tK24365 CSN9; COP9 signalosome complex subunit 9"
				},
				{
					"name":"KLMA_40409 PCI8; COP9 signalosome complex subunit 11\tK24367 PCI8; COP9 signalosome complex subunit 11"
				},
				{
					"name":"KLMA_70120 CSN12; COP9 signalosome complex subunit 12\tK24364 CSN12; COP9 signalosome complex subunit 12"
				}
				]
			}
			]
		}
		]
	}
	]
}