{
	"name":"kpe01011",
	"children":[
	{
		"name":"Precursor biosynthesis",
		"children":[
		{
			"name":"Transferase\/Dehydrogenase",
			"children":[
			{
				"name":"KPK_0522 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase\tK00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7]"
			},
			{
				"name":"KPK_5323 murB; UDP-N-acetylenolpyruvoylglucosamine reductase\tK00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98]"
			}
			]
		},
		{
			"name":"Amino acid ligase",
			"children":[
			{
				"name":"KPK_4646 murC; UDP-N-acetylmuramate--alanine ligase\tK01924 murC; UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8]"
			},
			{
				"name":"KPK_4649 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase\tK01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9]"
			},
			{
				"name":"KPK_4652 murE; UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase\tK01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13]"
			},
			{
				"name":"KPK_4364 ddlA; D-alanine--D-alanine ligase A\tK01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]"
			},
			{
				"name":"KPK_4645 ddlB; D-alanine--D-alanine ligase B\tK01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]"
			}
			]
		},
		{
			"name":"Racemase",
			"children":[
			{
				"name":"KPK_1986 alr_1; alanine racemase\tK01775 alr; alanine racemase [EC:5.1.1.1]"
			},
			{
				"name":"KPK_5235 alr_2; alanine racemase\tK01775 alr; alanine racemase [EC:5.1.1.1]"
			},
			{
				"name":"KPK_5425 murI; glutamate racemase\tK01776 murI; glutamate racemase [EC:5.1.1.3]"
			}
			]
		},
		{
			"name":"Carboxypeptidase",
			"children":[
			{
				"name":"KPK_1988 ldcA; muramoyltetrapeptide carboxypeptidase\tK01297 ldcA; muramoyltetrapeptide carboxypeptidase [EC:3.4.17.13]"
			}
			]
		},
		{
			"name":"Glycosyltransferase",
			"children":[
			{
				"name":"KPK_4650 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase\tK01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13]"
			},
			{
				"name":"KPK_4647 murG; undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase\tK02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227]"
			}
			]
		},
		{
			"name":"Diphosphatase",
			"children":[
			{
				"name":"KPK_0659 uppP; undecaprenyl-diphosphatase\tK06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27]"
			},
			{
				"name":"KPK_1137 PAP2 family protein\tK19302 bcrC; undecaprenyl-diphosphatase [EC:3.6.1.27]"
			},
			{
				"name":"KPK_3691 undecaprenyl-diphosphatase\tK19302 bcrC; undecaprenyl-diphosphatase [EC:3.6.1.27]"
			}
			]
		},
		{
			"name":"Flippase",
			"children":[
			{
				"name":"KPK_3476 mviN; integral membrane protein MviN\tK03980 murJ; putative peptidoglycan lipid II flippase"
			}
			]
		}
		]
	},
	{
		"name":"Peptidoglycan biosynthesis and degradation",
		"children":[
		{
			"name":"Glycosyltransferase\/DD-Transpeptidase (Class A PBP)",
			"children":[
			{
				"name":"KPK_0349 mrcA; penicillin-binding protein 1A\tK05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4]"
			},
			{
				"name":"KPK_4569 mrcB; penicillin-binding protein 1B\tK05365 mrcB; penicillin-binding protein 1B [EC:2.4.99.28 3.4.16.4]"
			},
			{
				"name":"KPK_1270 pbpC; penicillin-binding protein 1C\tK05367 pbpC; penicillin-binding protein 1C [EC:2.4.99.28]"
			}
			]
		},
		{
			"name":"DD-Transpeptidase (Class B PBP)",
			"children":[
			{
				"name":"KPK_2538 penicillin-binding protein\tK05515 mrdA; penicillin-binding protein 2 [EC:3.4.16.4]"
			},
			{
				"name":"KPK_3906 mrdA; penicillin-binding protein 2\tK05515 mrdA; penicillin-binding protein 2 [EC:3.4.16.4]"
			},
			{
				"name":"KPK_1954 putative peptidoglycan synthetase FtsI\tK03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4]"
			},
			{
				"name":"KPK_4653 ftsI; peptidoglycan synthetase FtsI\tK03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4]"
			}
			]
		},
		{
			"name":"DD-Carboxypeptidase\/DD-Endopeptidase (Low molecular weight PBP)",
			"children":[
			{
				"name":"KPK_1719 dacD; serine-type D-Ala-D-Ala carboxypeptidase\tK07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5\/6) [EC:3.4.16.4]"
			},
			{
				"name":"KPK_3693 dacC; serine-type D-Ala-D-Ala carboxypeptidase\tK07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5\/6) [EC:3.4.16.4]"
			},
			{
				"name":"KPK_3909 dacA; serine-type D-Ala-D-Ala carboxypeptidase\tK07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5\/6) [EC:3.4.16.4]"
			},
			{
				"name":"KPK_0529 dacB; D-alanyl-D-alanine carboxypeptidase\/D-alanyl-D-alanine-endopeptidase\tK07259 dacB; serine-type D-Ala-D-Ala carboxypeptidase\/endopeptidase (penicillin-binding protein 4) [EC:3.4.16.4 3.4.21.-]"
			},
			{
				"name":"KPK_4370 ampH; penicillin-binding protein AmpH\tK18988 ampH; serine-type D-Ala-D-Ala carboxypeptidase\/endopeptidase [EC:3.4.16.4 3.4.21.-]"
			},
			{
				"name":"KPK_1596 pbpG; penicillin-binding protein 7\tK07262 pbpG; serine-type D-Ala-D-Ala endopeptidase (penicillin-binding protein 7) [EC:3.4.21.-]"
			}
			]
		},
		{
			"name":"Glycosyltransferase",
			"children":[
			{
				"name":"KPK_0504 mtgA; monofunctional biosynthetic peptidoglycan transglycosylase\tK03814 mtgA; peptidoglycan glycosyltransferase [EC:2.4.99.28]"
			},
			{
				"name":"KPK_4648 ftsW; cell division protein FtsW\tK03588 ftsW; peptidoglycan glycosyltransferase [EC:2.4.99.28]"
			},
			{
				"name":"KPK_3907 mrdB; rod shape-determining protein RodA\tK05837 rodA; peptidoglycan glycosyltransferase [EC:2.4.99.28]"
			}
			]
		},
		{
			"name":"Transpeptidase",
			"children":[
			{
				"name":"KPK_1815 ErfK\/YbiS\/YcfS\/YnhG family protein\tK19236 ldtA_B_C_E; L,D-transpeptidase"
			},
			{
				"name":"KPK_2186 LysM domain\/ErfK\/YbiS\/YcfS\/YnhG family protein\tK19236 ldtA_B_C_E; L,D-transpeptidase"
			},
			{
				"name":"KPK_3443 LysM domain\/ErfK\/YbiS\/YcfS\/YnhG family protein\tK19236 ldtA_B_C_E; L,D-transpeptidase"
			},
			{
				"name":"KPK_3717 ybiS; YbiS protein\tK19236 ldtA_B_C_E; L,D-transpeptidase"
			},
			{
				"name":"KPK_3607 putative peptidoglycan binding protein\tK21470 ldtD; L,D-transpeptidase"
			},
			{
				"name":"KPK_4495 conserved hypothetical protein\tK28919 dpaA; peptidoglycan meso-diaminopimelic acid protein amidase A [EC:3.4.-.-]"
			}
			]
		},
		{
			"name":"Carboxypeptidase"
		},
		{
			"name":"Endopeptidase",
			"children":[
			{
				"name":"KPK_1421 mepA; penicillin-insensitive murein endopeptidase\tK07261 mepA; penicillin-insensitive murein DD-endopeptidase [EC:3.4.24.-]"
			},
			{
				"name":"KPK_2354 NlpC\/P60 family protein\tK19303 mepH; murein DD-endopeptidase [EC:3.4.-.-]"
			},
			{
				"name":"KPK_1553 spr; lipoprotein Spr\tK13694 mepS; murein DD-endopeptidase \/ murein LD-carboxypeptidase [EC:3.4.-.- 3.4.17.13]"
			},
			{
				"name":"KPK_1913 metalloprotease, opacity-associated protein A family\tK19304 mepM; murein DD-endopeptidase [EC:3.4.24.-]"
			}
			]
		},
		{
			"name":"Sortase"
		},
		{
			"name":"Lytic transglycosylase",
			"children":[
			{
				"name":"KPK_4767 transglycosylase SLT domain protein\tK08309 slt; peptidoglycan lytic transglycosylase [EC:4.2.2.29]"
			},
			{
				"name":"KPK_0953 mltA; membrane-bound lytic murein transglycosylase A\tK08304 mltA; peptidoglycan lytic transglycosylase A [EC:4.2.2.29]"
			},
			{
				"name":"KPK_1090 mltB; lytic murein transglycosylase B\tK08305 mltB; peptidoglycan lytic transglycosylase B [EC:4.2.2.29]"
			},
			{
				"name":"KPK_0714 mltC; membrane-bound lytic murein transglycosylase C\tK08306 mltC; peptidoglycan lytic transglycosylase C [EC:4.2.2.29]"
			},
			{
				"name":"KPK_4508 mltD; membrane-bound lytic murein transglycosylase D\tK08307 mltD; peptidoglycan lytic transglycosylase D [EC:4.2.2.29]"
			},
			{
				"name":"KPK_1989 mltE; membrane-bound lytic murein transglycosylase E\tK08308 mltE; peptidoglycan lytic transglycosylase E [EC:4.2.2.29]"
			},
			{
				"name":"KPK_1238 bacterial extracellular solute-binding, family 3\/transglycosylase SLT domain protein\tK18691 mltF; peptidoglycan lytic transglycosylase F [EC:4.2.2.29]"
			},
			{
				"name":"KPK_3461 conserved hypothetical protein\tK07082 mltG; peptidoglycan lytic transglycosylase G [EC:4.2.2.29]"
			},
			{
				"name":"KPK_3908 rlpA; rare lipoprotein A\tK03642 rlpA; peptidoglycan lytic transglycosylase [EC:4.2.2.29]"
			}
			]
		},
		{
			"name":"Amidase",
			"children":[
			{
				"name":"KPK_0890 amiC; N-acetylmuramoyl-L-alanine amidase AmiC\tK01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]"
			},
			{
				"name":"KPK_1359 amiA; N-acetylmuramoyl-L-alanine amidase\tK01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]"
			},
			{
				"name":"KPK_5101 amiB; N-acetylmuramoyl-L-alanine amidase\tK01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]"
			},
			{
				"name":"KPK_3661 amiD; N-acetylmuramoyl-L-alanine amidase amiD\tK11066 amiD; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]"
			},
			{
				"name":"KPK_4628 ampD; N-acetylmuramoyl-L-alanine amidase\tK03806 ampD; N-acetyl-anhydromuramoyl-L-alanine amidase [EC:3.5.1.28]"
			}
			]
		},
		{
			"name":"Structural protein",
			"children":[
			{
				"name":"KPK_2187 lpp; major outer membrane lipoprotein\tK06078 lpp; murein lipoprotein"
			}
			]
		}
		]
	}
	]
}