{
	"name":"kpie01011",
	"children":[
	{
		"name":"Precursor biosynthesis",
		"children":[
		{
			"name":"Transferase\/Dehydrogenase",
			"children":[
			{
				"name":"N5580_16245 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase\tK00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7]"
			},
			{
				"name":"N5580_17145 murB; UDP-N-acetylmuramate dehydrogenase\tK00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98]"
			}
			]
		},
		{
			"name":"Amino acid ligase",
			"children":[
			{
				"name":"N5580_15215 murC; UDP-N-acetylmuramate--L-alanine ligase\tK01924 murC; UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8]"
			},
			{
				"name":"N5580_15230 murD; UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase\tK01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9]"
			},
			{
				"name":"N5580_15245 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase\tK01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13]"
			},
			{
				"name":"N5580_02345 ddlA; D-alanine--D-alanine ligase\tK01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]"
			},
			{
				"name":"N5580_15210 D-alanine--D-alanine ligase\tK01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]"
			}
			]
		},
		{
			"name":"Racemase",
			"children":[
			{
				"name":"N5580_07695 dadX; catabolic alanine racemase DadX\tK01775 alr; alanine racemase [EC:5.1.1.1]"
			},
			{
				"name":"N5580_21500 dadX; catabolic alanine racemase DadX\tK01775 alr; alanine racemase [EC:5.1.1.1]"
			},
			{
				"name":"N5580_00365 murI; glutamate racemase\tK01776 murI; glutamate racemase [EC:5.1.1.3]"
			}
			]
		},
		{
			"name":"Carboxypeptidase",
			"children":[
			{
				"name":"N5580_10375 ldcA; muramoyltetrapeptide carboxypeptidase\tK01297 ldcA; muramoyltetrapeptide carboxypeptidase [EC:3.4.17.13]"
			}
			]
		},
		{
			"name":"Glycosyltransferase",
			"children":[
			{
				"name":"N5580_15235 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase\tK01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13]"
			},
			{
				"name":"N5580_15220 murG; undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase\tK02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227]"
			}
			]
		},
		{
			"name":"Diphosphatase",
			"children":[
			{
				"name":"N5580_02570 bacA; undecaprenyl-diphosphate phosphatase\tK06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27]"
			},
			{
				"name":"N5580_09055 undecaprenyl-diphosphatase\tK19302 bcrC; undecaprenyl-diphosphatase [EC:3.6.1.27]"
			},
			{
				"name":"N5580_11780 ybjG; undecaprenyl-diphosphate phosphatase\tK19302 bcrC; undecaprenyl-diphosphatase [EC:3.6.1.27]"
			}
			]
		},
		{
			"name":"Flippase",
			"children":[
			{
				"name":"N5580_10970 murJ; murein biosynthesis integral membrane protein MurJ\tK03980 murJ; putative peptidoglycan lipid II flippase"
			}
			]
		}
		]
	},
	{
		"name":"Peptidoglycan biosynthesis and degradation",
		"children":[
		{
			"name":"Glycosyltransferase\/DD-Transpeptidase (Class A PBP)",
			"children":[
			{
				"name":"N5580_01205 mrcA; peptidoglycan glycosyltransferase\/peptidoglycan DD-transpeptidase MrcA\tK05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4]"
			},
			{
				"name":"N5580_14915 mrcB; bifunctional glycosyl transferase\/transpeptidase\tK05365 mrcB; penicillin-binding protein 1B [EC:2.4.99.28 3.4.16.4]"
			},
			{
				"name":"N5580_04390 pbpC; peptidoglycan glycosyltransferase PbpC\tK05367 pbpC; penicillin-binding protein 1C [EC:2.4.99.28]"
			}
			]
		},
		{
			"name":"DD-Transpeptidase (Class B PBP)",
			"children":[
			{
				"name":"N5580_02910 mrdA; penicillin-binding protein 2\tK05515 mrdA; penicillin-binding protein 2 [EC:3.4.16.4]"
			},
			{
				"name":"N5580_12735 mrdA; peptidoglycan DD-transpeptidase MrdA\tK05515 mrdA; penicillin-binding protein 2 [EC:3.4.16.4]"
			},
			{
				"name":"N5580_03500 penicillin-binding transpeptidase domain-containing protein\tK03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4]"
			},
			{
				"name":"N5580_15250 peptidoglycan glycosyltransferase FtsI\tK03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4]"
			}
			]
		},
		{
			"name":"DD-Carboxypeptidase\/DD-Endopeptidase (Low molecular weight PBP)",
			"children":[
			{
				"name":"N5580_06370 dacD; serine-type D-Ala-D-Ala carboxypeptidase DacD\tK07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5\/6) [EC:3.4.16.4]"
			},
			{
				"name":"N5580_11785 serine hydrolase\tK07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5\/6) [EC:3.4.16.4]"
			},
			{
				"name":"N5580_12750 dacA; D-alanyl-D-alanine carboxypeptidase DacA\tK07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5\/6) [EC:3.4.16.4]"
			},
			{
				"name":"N5580_16135 dacB; serine-type D-Ala-D-Ala carboxypeptidase\tK07259 dacB; serine-type D-Ala-D-Ala carboxypeptidase\/endopeptidase (penicillin-binding protein 4) [EC:3.4.16.4 3.4.21.-]"
			},
			{
				"name":"N5580_04705 ampH; D-alanyl-D-alanine-carboxypeptidase\/endopeptidase AmpH\tK18988 ampH; serine-type D-Ala-D-Ala carboxypeptidase\/endopeptidase [EC:3.4.16.4 3.4.21.-]"
			},
			{
				"name":"N5580_12095 pbpG; D-alanyl-D-alanine endopeptidase\tK07262 pbpG; serine-type D-Ala-D-Ala endopeptidase (penicillin-binding protein 7) [EC:3.4.21.-]"
			}
			]
		},
		{
			"name":"Glycosyltransferase",
			"children":[
			{
				"name":"N5580_16335 mtgA; monofunctional biosynthetic peptidoglycan transglycosylase\tK03814 mtgA; peptidoglycan glycosyltransferase [EC:2.4.99.28]"
			},
			{
				"name":"N5580_15225 ftsW; cell division protein FtsW\tK03588 ftsW; peptidoglycan glycosyltransferase [EC:2.4.99.28]"
			},
			{
				"name":"N5580_12740 mrdB; peptidoglycan glycosyltransferase MrdB\tK05837 rodA; peptidoglycan glycosyltransferase [EC:2.4.99.28]"
			}
			]
		},
		{
			"name":"Transpeptidase",
			"children":[
			{
				"name":"N5580_09770 L,D-transpeptidase family protein\tK19236 ldtA_B_C_E; L,D-transpeptidase"
			},
			{
				"name":"N5580_12120 L,D-transpeptidase family protein\tK19236 ldtA_B_C_E; L,D-transpeptidase"
			},
			{
				"name":"N5580_11475 ldtD; L,D-transpeptidase\tK21470 ldtD; L,D-transpeptidase"
			},
			{
				"name":"N5580_14450 dpaA; peptidoglycan meso-diaminopimelic acid protein amidase\tK28919 dpaA; peptidoglycan meso-diaminopimelic acid protein amidase A [EC:3.4.-.-]"
			}
			]
		},
		{
			"name":"Carboxypeptidase"
		},
		{
			"name":"Endopeptidase",
			"children":[
			{
				"name":"N5580_05265 mepA; penicillin-insensitive murein endopeptidase\tK07261 mepA; penicillin-insensitive murein DD-endopeptidase [EC:3.4.24.-]"
			},
			{
				"name":"N5580_09705 C40 family peptidase\tK19303 mepH; murein DD-endopeptidase [EC:3.4.-.-]"
			},
			{
				"name":"N5580_05720 mepS; bifunctional murein DD-endopeptidase\/murein LD-carboxypeptidase\tK13694 mepS; murein DD-endopeptidase \/ murein LD-carboxypeptidase [EC:3.4.-.- 3.4.17.13]"
			},
			{
				"name":"N5580_07380 mepM; murein DD-endopeptidase MepM\tK19304 mepM; murein DD-endopeptidase [EC:3.4.24.-]"
			}
			]
		},
		{
			"name":"Sortase"
		},
		{
			"name":"Lytic transglycosylase",
			"children":[
			{
				"name":"N5580_15550 sltY; murein transglycosylase\tK08309 slt; peptidoglycan lytic transglycosylase [EC:4.2.2.29]"
			},
			{
				"name":"N5580_14330 mltA; murein transglycosylase A\tK08304 mltA; peptidoglycan lytic transglycosylase A [EC:4.2.2.29]"
			},
			{
				"name":"N5580_03700 mltB; lytic murein transglycosylase B\tK08305 mltB; peptidoglycan lytic transglycosylase B [EC:4.2.2.29]"
			},
			{
				"name":"N5580_03105 mltC; membrane-bound lytic murein transglycosylase MltC\tK08306 mltC; peptidoglycan lytic transglycosylase C [EC:4.2.2.29]"
			},
			{
				"name":"N5580_14630 mltD; murein transglycosylase D\tK08307 mltD; peptidoglycan lytic transglycosylase D [EC:4.2.2.29]"
			},
			{
				"name":"N5580_10370 emtA; membrane-bound lytic murein transglycosylase EmtA\tK08308 mltE; peptidoglycan lytic transglycosylase E [EC:4.2.2.29]"
			},
			{
				"name":"N5580_04285 mltF; membrane-bound lytic murein transglycosylase MltF\tK18691 mltF; peptidoglycan lytic transglycosylase F [EC:4.2.2.29]"
			},
			{
				"name":"N5580_10835 mltG; endolytic transglycosylase MltG\tK07082 mltG; peptidoglycan lytic transglycosylase G [EC:4.2.2.29]"
			},
			{
				"name":"N5580_12745 rlpA; endolytic peptidoglycan transglycosylase RlpA\tK03642 rlpA; peptidoglycan lytic transglycosylase [EC:4.2.2.29]"
			}
			]
		},
		{
			"name":"Amidase",
			"children":[
			{
				"name":"N5580_01925 amiB; N-acetylmuramoyl-L-alanine amidase AmiB\tK01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]"
			},
			{
				"name":"N5580_04730 amiA; N-acetylmuramoyl-L-alanine amidase AmiA\tK01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]"
			},
			{
				"name":"N5580_14355 amiC; N-acetylmuramoyl-L-alanine amidase AmiC\tK01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]"
			},
			{
				"name":"N5580_11675 N-acetylmuramoyl-L-alanine amidase\tK11066 amiD; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]"
			},
			{
				"name":"N5580_15130 ampD; 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD\tK03806 ampD; N-acetyl-anhydromuramoyl-L-alanine amidase [EC:3.5.1.28]"
			}
			]
		},
		{
			"name":"Structural protein",
			"children":[
			{
				"name":"N5580_09765 major outer membrane lipoprotein\tK06078 lpp; murein lipoprotein"
			}
			]
		}
		]
	}
	]
}